Page last updated: 2024-08-17

aspartic acid and Drug Withdrawal Symptoms

aspartic acid has been researched along with Drug Withdrawal Symptoms in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's9 (36.00)18.2507
2000's7 (28.00)29.6817
2010's4 (16.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baandrup, L; Ebdrup, BH; Glenthøj, BY; Gluud, C; Lindschou, J; Rasmussen, JØ1
Fischer, KD; Houston, AC; Rebec, GV1
Morgenstern, R; Netzhammer, N; Seidemann, T; Spies, C; Wernecke, KD1
Demirakca, T; Dieter, S; Ende, G; Falfan-Melgoza, C; Frischknecht, U; Hermann, D; Kiefer, F; Krumm, B; Mann, KF; Sack, M; Sommer, WH; Spanagel, R; Tunc-Skarka, N; van Eijk, J; Wang, GY; Weber-Fahr, W1
Adalsteinsson, E; Flynn, N; Galloway, GP; Gibson, DR; Leamon, M; Nordahl, TE; Pfefferbaum, A; Possin, K; Salo, R; Spielman, DM; Sullivan, EV1
Minami, M; Nakagawa, T; Ozawa, T; Satoh, M; Sekiya, Y1
Kendig, JJ; Peters, MC; Sweitzer, SM; Wong, SME1
Buonocore, MH; Galloway, GP; Kile, S; Moore, CD; Natsuaki, Y; Nordahl, TE; Salo, R; Waters, C1
Aghajanian, GK; Kogan, JH; Moghaddam, B1
Feng, Y; Ho, IK; Rockhold, RW; Zhang, T1
Ho, IK; Hoshi, K; Ma, T1
Contreras, E; Hernandez, L; Rada, P; Sepulveda, MJ; Tucci, S1
Chang, R; Chen, S; Coyle, JT; Linnoila, VM; Ragan, P; Tsai, GE1
Hanin, I; Kindel, G; Wülfert, E; Zhang, X1
Chen, JC; Chiang, YC; Huang, YK; Liang, CS; Liang, KW1
Nakagawa, T1
Favalli, L; Frattini, P; Govoni, S; Masoero, E; Pascale, A; Rozza, A; Scelsi, R1
Eroğlu, L; Güngör, M; Koyuncuoğlu, H; Sağduyu, H1
Ariciŏglu, F; Dizdar, Y; Esin, Y; Koyuncuŏglu, H; Uresin, Y1
Little, HJ1
Aricioğlu, F; Güngör, M; Koyuncuoğlu, H; Sağduyu, H1
McCaslin, PP; Morgan, WW2
Ceylan, ME; Koyuncuoğlu, H; Sener, AI1
Harris, RL; Hawkins, RA; Miller, AL; Veech, RL1

Reviews

3 review(s) available for aspartic acid and Drug Withdrawal Symptoms

ArticleYear
Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users.
    The Cochrane database of systematic reviews, 2018, Mar-15, Volume: 3

    Topics: Adult; Antidepressive Agents; Aspartic Acid; Benzodiazepines; Buspirone; Carbamazepine; Ethylamines; Flumazenil; Homeopathy; Humans; Imidazoles; Lithium Compounds; Melatonin; Paroxetine; Pregabalin; Progesterone; Pyridines; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Sulfides; Withholding Treatment

2018
[Involvement of glial glutamate transporters in morphine dependence and naloxone-precipitated withdrawal].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2001, Volume: 121, Issue:9

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Brain; Cells, Cultured; Excitatory Amino Acid Transporter 2; Gene Expression; Humans; Morphine Dependence; Naloxone; RNA, Messenger; Substance Withdrawal Syndrome

2001
Mechanisms that may underlie the behavioural effects of ethanol.
    Progress in neurobiology, 1991, Volume: 36, Issue:3

    Topics: Alcoholic Intoxication; Animals; Aspartic Acid; Behavior; Behavior, Animal; Calcium; Calcium Channels; Cell Membrane; Dihydropyridines; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Ion Channel Gating; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synaptic Transmission

1991

Trials

1 trial(s) available for aspartic acid and Drug Withdrawal Symptoms

ArticleYear
Comparison of the suppressive effects of L-aspartic acid and chlorpromazine + diazepam treatments on opiate abstinence syndrome signs in men.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:11

    Topics: Aspartic Acid; Chlorpromazine; Diazepam; Drug Therapy, Combination; Humans; Male; Opioid-Related Disorders; Substance Withdrawal Syndrome

1986

Other Studies

21 other study(ies) available for aspartic acid and Drug Withdrawal Symptoms

ArticleYear
Role of the major glutamate transporter GLT1 in nucleus accumbens core versus shell in cue-induced cocaine-seeking behavior.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, May-29, Volume: 33, Issue:22

    Topics: Analysis of Variance; Animals; Aspartic Acid; Behavior, Animal; Blotting, Western; Ceftriaxone; Cocaine-Related Disorders; Conditioning, Operant; Cues; Excitatory Amino Acid Transporter 2; Feeding Behavior; Kainic Acid; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Substance Withdrawal Syndrome

2013
Influence of Volatile Anesthesia on the Release of Glutamate and other Amino Acids in the Nucleus Accumbens in a Rat Model of Alcohol Withdrawal: A Pilot Study.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Amino Acids; Anesthesia, Inhalation; Animals; Arginine; Aspartic Acid; Desflurane; Disease Models, Animal; Feeding Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Isoflurane; Male; Microdialysis; Nucleus Accumbens; Pilot Projects; Rats, Wistar; Substance Withdrawal Syndrome; Time Factors; Volatilization

2017
Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats.
    Alcoholism, clinical and experimental research, 2017, Volume: 41, Issue:2

    Topics: Adult; Alcohol Abstinence; Alcoholism; Animals; Aspartic Acid; Biomarkers; Female; Glutamic Acid; Gray Matter; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Rats; Rats, Wistar; Species Specificity; Substance Withdrawal Syndrome; Translational Research, Biomedical

2017
Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine-dependent subjects: a preliminary proton MRS study. Magnetic resonance spectroscopy.
    Psychiatry research, 2002, Nov-30, Volume: 116, Issue:1-2

    Topics: Adult; Age Factors; Amphetamine-Related Disorders; Aspartic Acid; Choline; Creatine; Dopamine; Frontal Lobe; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Neurons; Serotonin; Substance Withdrawal Syndrome; Visual Cortex

2002
Facilitation of morphine withdrawal symptoms and morphine-induced conditioned place preference by a glutamate transporter inhibitor DL-threo-beta-benzyloxyaspartate in rats.
    European journal of pharmacology, 2004, Feb-06, Volume: 485, Issue:1-3

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Conditioning, Operant; Male; Morphine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

2004
Hyperresponsiveness on washout of volatile anesthetics from isolated spinal cord compared to withdrawal from ethanol.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Bronchial Hyperreactivity; Calcitonin Gene-Related Peptide; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Electric Stimulation; Enzyme Inhibitors; Ethanol; Excitatory Postsynaptic Potentials; Glutamic Acid; Indoles; Maleimides; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Substance Withdrawal Syndrome

2005
Methamphetamine users in sustained abstinence: a proton magnetic resonance spectroscopy study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:4

    Topics: Adult; Ambulatory Care; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dopamine; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Phosphocreatine; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Tissue Distribution; Visual Cortex

2005
Opiate withdrawal increases glutamate and aspartate efflux in the locus coeruleus: an in vivo microdialysis study.
    Brain research, 1994, Feb-04, Volume: 636, Issue:1

    Topics: Animals; Aspartic Acid; Drug Implants; Extracellular Space; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Microdialysis; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

1994
Naloxone-precipitated morphine withdrawal increases pontine glutamate levels in the rat.
    Life sciences, 1994, Volume: 55, Issue:2

    Topics: Animals; Aspartic Acid; Dialysis; Drug Interactions; Glutamates; Glutamic Acid; Locus Coeruleus; Male; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

1994
Precipitated kappa-opioid receptor agonist withdrawal increase glutamate in rat locus coeruleus.
    European journal of pharmacology, 1996, Oct-31, Volume: 314, Issue:3

    Topics: Analgesics; Analysis of Variance; Animals; Aspartic Acid; Benzeneacetamides; Butorphanol; Glutamic Acid; Injections, Intraventricular; Locus Coeruleus; Male; Microdialysis; Naloxone; Narcotic Antagonists; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome

1996
Effect of precipitated withdrawal on extracellular glutamate and aspartate in the nucleus accumbens of chronically morphine-treated rats: an in vivo microdialysis study.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1

    Topics: Animals; Aspartic Acid; Calcium; Extracellular Space; Glutamic Acid; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome

1998
Increased glutamatergic neurotransmission and oxidative stress after alcohol withdrawal.
    The American journal of psychiatry, 1998, Volume: 155, Issue:6

    Topics: Adult; Alcoholism; Aspartic Acid; Dipeptides; Ethanol; Excitatory Amino Acids; Female; gamma-Aminobutyric Acid; Glutamates; Humans; Male; Middle Aged; Oxidative Stress; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Superoxide Dismutase; Synaptic Transmission; Up-Regulation

1998
Mivazerol inhibits intrathecal release of glutamate evoked by halothane withdrawal in rats.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:8

    Topics: Adrenergic alpha-Agonists; Anesthesia; Anesthetics, Inhalation; Animals; Aspartic Acid; Blood Pressure; Glutamic Acid; Halothane; Heart Rate; Imidazoles; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance Withdrawal Syndrome

1998
Significance of glutamate and dopamine neurons in the ventral pallidum in the expression of behavioral sensitization to amphetamine.
    Life sciences, 2001, Jan-19, Volume: 68, Issue:9

    Topics: Amphetamine; Animals; Aspartic Acid; Behavior, Animal; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Globus Pallidus; Glutamic Acid; Male; Motor Activity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome

2001
Ischemia-induced glutamate release in rat frontoparietal cortex after chronic alcohol and withdrawal.
    Neuroscience letters, 2002, Jul-05, Volume: 326, Issue:3

    Topics: Alcoholism; Animals; Aspartic Acid; Central Nervous System Depressants; Dialysis Solutions; Ethanol; Glutamic Acid; Ischemic Attack, Transient; Male; Microdialysis; Parietal Lobe; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2002
The antagonizing effect of aspartic acid on morphine withdrawal and levallorphan-precipitated abstinence syndrome signs and on associated changes in brain levels of free amino acids in the rat.
    Psychopharmacology, 1979, Mar-29, Volume: 62, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain Chemistry; Humans; Levallorphan; Motor Activity; Rats; Substance Withdrawal Syndrome; Time Factors

1979
Effects of tizanidine on morphine physical dependence: attenuation and intensification.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Aspartic Acid; Behavior, Animal; Clonidine; Glutamates; Glutamic Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1992
Intensification and attenuation of morphine dependence by D-aspartic acid and PLG.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:1

    Topics: Animals; Asparaginase; Aspartic Acid; Brain; Mice; Mice, Inbred BALB C; Morphine Dependence; MSH Release-Inhibiting Hormone; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1990
Increased response of cerebellar cGMP to kainate but not NMDA or quisqualate following barbital withdrawal from dependent rats.
    European journal of pharmacology, 1989, Dec-07, Volume: 173, Issue:2-3

    Topics: Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders

1989
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
    Neuropharmacology, 1987, Volume: 26, Issue:7A

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders

1987
The effects of acute and chronic morphine treatment and of morphine withdrawal on rat brain in vivo.
    The Biochemical journal, 1972, Volume: 129, Issue:2

    Topics: Acetazolamide; Adenosine Diphosphate; Adenosine Triphosphate; Ammonia; Animals; Arteries; Aspartic Acid; Brain; Carbon Dioxide; Citrates; Glucose; Glutarates; Humans; Hydrogen-Ion Concentration; Lactates; Malates; Male; Morphine; Morphine Dependence; Nalorphine; Phosphocreatine; Pyruvates; Rats; Substance Withdrawal Syndrome

1972