aspartic acid has been researched along with Diabetes Mellitus, Adult-Onset in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.92) | 18.7374 |
| 1990's | 5 (9.80) | 18.2507 |
| 2000's | 16 (31.37) | 29.6817 |
| 2010's | 20 (39.22) | 24.3611 |
| 2020's | 8 (15.69) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, L; Li, C; Man, F; Pan, Q; Wang, W; Wang, X; Wu, MX; Xian, TZ; Zhang, J; Zhang, X | 1 |
| Cao, H; Li, J; Li, X; Luo, GH; Wang, JW; Wei, N; Wu, SS; Ye, XY; Zhang, ZH | 1 |
| Li, Z; Lv, Y; Wang, G; Zhao, X; Zheng, Y | 1 |
| Bain, J; Colón-Emeric, C; Ilkayeva, O; Lee, RH; Muehlbauer, M; Pieper, C; Wixted, D | 1 |
| Goda, K; Kenzaka, T; Mizutani, N | 1 |
| Feng, Y; Jie, Q; Liang, W; Qin, J; Wu, W; Yang, D; Zhi, X | 1 |
| Fukuda, M; Nagao, Y | 1 |
| Hong, Q; Li, S; Lian, X; Yin, C; Zhao, W | 1 |
| Fang, ZZ; Feng, XF; Hou, RQ; Luo, HH; Yang, XL | 1 |
| Jing, L; Qiu, TC; Tan, Y; Wu, GY; Wu, JL; Zhang, Q; Zhao, J | 1 |
| Hu, C; Jia, W; Jiang, F; Wang, J; Wang, S; Yan, D; Zhang, R; Zhao, A; Zheng, X | 1 |
| Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
| Bolo, NR; Fried, PJ; Pascual-Leone, A | 1 |
| An, Z; Chen, H; Li, Y; Lin, Y; Liu, L; Qu, X; Sha, L; Sun, C; Wang, Y; Zhou, J | 1 |
| Birkler, RI; Bøtker, HE; Dalgas, C; Johannsen, M; Løfgren, B; Povlsen, JA; Støttrup, NB | 1 |
| Chen, J; Geng, H; Ma, X; Meng, Q; Sun, L; Sun, X; Wang, Y; Zhang, M; Zhang, Z | 1 |
| Alda, M; Blagdon, R; Calkin, C; Hajek, T; Slaney, C | 1 |
| Ekka, M; Jagannathan, NR; P, R; Pandey, RM; Sharma, U; Sinha, S | 1 |
| Geng, H; Liang, Q; Meng, Q; Qian, R; Sun, L; Sun, X; Tong, J; Zhang, M; Zhang, Z; Zhu, X | 1 |
| Hu, AM; Liu, HL; Sun, QQ; Wang, Q; Yin, YW | 1 |
| Adriaenssens, AE; Andersson, LE; Bagge, A; Gribble, F; Mulder, H; Reimann, F; Sharoyko, VV; Spégel, P; Stamenkovic, JA; Wollheim, CB | 1 |
| Desmet, KJ; Gillard, P; Harteveld, CL; Kieffer, DM; Lee, DH; Schiemsky, T | 1 |
| Niu, H; Shen, J; Shi, X; Wang, R; Wang, S; Wu, J; Yang, H; Zhang, Y; Zhou, S | 1 |
| Achilles, EI; Fink, GR; Maintz, D; Maus, V; Mpotsaris, A; van Eimeren, T | 1 |
| Groop, PH; Heikkilä, O; Heikkinen, S; Lundbom, N; Mäkimattila, S; Timonen, M | 1 |
| Larsson, CA; Lindblad, U; Odeberg, J; Råstam, L | 1 |
| Abid, HK; Ben Maiz, H; Benammar-Elgaaied, A; Flores Martinez, SE; Ouederni, TB; Sanchez-Corona, J; Skhiri, HA | 1 |
| Biessels, GJ; Kappelle, J; Luijten, P; Mali, W; Pleizier, M; Tiehuis, A; van der Meer, F | 1 |
| Benie, AJ; Bouman, SD; Schousboe, A; Sickmann, HM; Waagepetersen, HS | 2 |
| Han, W; Lee, P; Leong, W; Lim, M; Radda, GK; Tan, T | 1 |
| D'Alfonso, R; Federici, M; Frittitta, L; Frontoni, S; Gambardella, S; Lauro, D; Lauro, R; Mariani, LM; Marini, MA; Porzio, O; Sesti, G; Sorge, R; Trischitta, V | 1 |
| Baier, LJ; Bogardus, C; Hanson, RL; Kovacs, P; Lehn-Stefan, A; Permana, PA; Silver, K; Stefan, N; Stumvoll, M; Tataranni, PA | 1 |
| Feuerbach, S; Fründ, R; Geissler, A; Schölmerich, J; Zietz, B | 1 |
| Bierhaus, A; Chavakis, T; Hamann, A; Humpert, PM; Isermann, B; Nawroth, P; Nosikov, VV; Reismann, P; Rudofsky, G; Tafel, J; Witte, S | 1 |
| Chen, MW; Liu, SQ; Sun, HY; Wang, CJ; Wang, YM; Xu, XP; Yang, MG; Zhang, Q | 1 |
| Elbein, SC; Karim, MA | 1 |
| Beck, SR; Bowden, DW; Burdon, KP; Freedman, BI; Langefeld, CD; Liu, Y; Rich, SS; Wagenknecht, LE | 1 |
| Kazahari, M; Kikuchi, N; Koike, A; Matsuura, N; Nomoto, K; Ohtsu, S; Takubo, N; Yokota, F | 1 |
| Ajilore, O; Binesh, N; Darwin, C; Haroon, E; Kumar, A; Kumaran, S; Miller, J; Mintz, J; Thomas, MA | 1 |
| Aslanidis, C; Buechler, C; Herfarth, H; Schäffler, A; Wobser, H; Zeitoun, M | 1 |
| Bhattacharya, M; Khushu, S; Modi, S; Rana, P; Sekhri, T; Tripathi, RP | 1 |
| Babaya, N; Fujisawa, T; Hamada, Y; Ikegami, H; Kawabata, Y; Kawaguchi, Y; Nojima, K; Ogihara, T; Shen, GQ; Shintani, M; Ueda, H; Yamada, K | 1 |
| Bach, JF; Boitard, C; Caillat-Zucman, S; Djilali-Saiah, I; Dubois-Laforgue, D; Larger, E; Mercadier, A; Timsit, J | 1 |
| Bissé, E; Eigel, A; Huaman-Guillen, P; Lizama, M; März, W; Van Dorsselaer, A; Wieland, H; Zorn, N | 1 |
| Cai, H; Colagiuri, S; Wang, X; Wilcken, DE | 1 |
| Egawa, K; Haneda, M; Hidaka, H; Iwai, N; Kashiwagi, A; Kikkawa, R; Kinoshita, M; Kojima, H; Maegawa, H; Nakamura, Y; Nishio, Y; Shi, K; Yasuda, H | 1 |
| Ahn, YH; Bae, JH; Earm, YE; Ho, WK; Hong, YS; Park, WK; Song, DK | 1 |
| Boitard, C; Caillat-Zucman, S; Dubois-Laforgue, D; Timsit, J | 1 |
| Filer, LJ; Stegink, LD | 1 |
| Berdanier, CD; Deaver, OE; McCusker, RH; Wander, RC | 1 |
2 review(s) available for aspartic acid and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Changes in cerebral metabolites in type 2 diabetes mellitus: A meta-analysis of proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Diabetes Mellitus, Type 2; Humans; Inositol; Proton Magnetic Resonance Spectroscopy | 2017 |
Toll-like receptor 4 gene Asp299Gly and Thr399Ile polymorphisms in type 2 diabetes mellitus: a meta-analysis of 15,059 subjects.
Topics: Amino Acid Substitution; Aspartic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glycine; Humans; Isoleucine; Models, Genetic; Observational Studies as Topic; Polymorphism, Single Nucleotide; Threonine; Toll-Like Receptor 4 | 2015 |
1 trial(s) available for aspartic acid and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Comparing the effects of twice-daily exenatide and insulin on renal function in patients with type 2 diabetes mellitus: secondary analysis of a randomized controlled trial.
Topics: Aspartic Acid; Diabetes Mellitus, Type 2; Exenatide; Glucagon-Like Peptide-1 Receptor; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Kidney; Obesity; Overweight; Peptides; Venoms | 2022 |
48 other study(ies) available for aspartic acid and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Reactive Oxygen Species Contributes to Type 2 Diabetic Neuropathic Pain via the Thioredoxin-Interacting Protein-NOD-Like Receptor Protein 3- N -Methyl-D-Aspartic Acid Receptor 2B Pathway.
Topics: Animals; Aspartic Acid; Caspases; Cell Cycle Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Glucose; Inflammasomes; Interleukin-1beta; Male; Neuralgia; NLR Family, Pyrin Domain-Containing 3 Protein; NLR Proteins; Peptide Hydrolases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Amino Acid; RNA; Streptozocin; Thioredoxins | 2022 |
The relationship between islet β-cell function and metabolomics in overweight patients with Type 2 diabetes.
Topics: Adult; Aspartic Acid; Blood Glucose; Body Mass Index; Cross-Sectional Studies; Cysteine; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Metabolomics; Overweight | 2023 |
Metabolic factors associated with incident fracture among older adults with type 2 diabetes mellitus: a nested case-control study.
Topics: Aged; Amino Acids; Asparagine; Aspartic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Fatty Acids; Fractures, Bone; Glutamine; Humans; Middle Aged; Risk Factors | 2023 |
A Case of Milk-Alkali Syndrome Caused by Diuretic-Induced Alkalosis and Polypharmacy.
Topics: Aged; Aged, 80 and over; Alkalosis; Aspartic Acid; Calcium; Diabetes Mellitus, Type 2; Diuretics; Female; Humans; Hypercalcemia; Hypophosphatemia; Kidney Diseases; Polypharmacy | 2023 |
Oral probiotics increased the proportion of Treg, Tfr, and Breg cells to inhibit the inflammatory response and impede gestational diabetes mellitus.
Topics: Animals; Asparagine; Aspartic Acid; B-Lymphocytes, Regulatory; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dysbiosis; Female; Humans; Inflammation; Leptin; Mice; Pregnancy; T-Lymphocytes, Regulatory | 2023 |
Dynamic derangement in amino acid profile during and after a stroke-like episode in adult-onset mitochondrial disease: a case report.
Topics: Arginine; Aspartic Acid; Biomarkers; Deafness; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Growth Differentiation Factor 15; Humans; Male; MELAS Syndrome; Middle Aged; Mitochondrial Diseases; Mutation | 2019 |
Application of Hydrogen Proton Magnetic Resonance Technology Combined with Brain Neurometabolite Analysis in the Treatment of Cognitive Impairment Caused by Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Aspartic Acid; Cognitive Dysfunction; Diabetes Mellitus, Type 2; Female; Humans; Hydrogen; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Protons; Treatment Outcome | 2020 |
Interactive effects of asparagine and aspartate homeostasis with sex and age for the risk of type 2 diabetes risk.
Topics: Adolescent; Adult; Aging; Asian People; Asparagine; Aspartic Acid; China; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Sex Factors; Young Adult | 2020 |
Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach.
Topics: Adult; Aged; Aspartic Acid; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glutamic Acid; Haptoglobins; Humans; Male; Metabolomics; Middle Aged; Phosphatidylcholines | 2019 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex.
Topics: Aged; Aged, 80 and over; Aging; Aspartic Acid; Creatine; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Glutamic Acid; Glutamine; Glutathione; Glycerylphosphorylcholine; Humans; Inositol; Insulin Resistance; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Neuronal Plasticity; Phosphocreatine; Phosphorylcholine; Prediabetic State; Theta Rhythm; Transcranial Magnetic Stimulation | 2019 |
Metabolite differences in the lenticular nucleus in type 2 diabetes mellitus shown by proton MR spectroscopy.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Choline; Corpus Striatum; Creatine; Diabetes Mellitus, Type 2; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Reproducibility of Results; Sensitivity and Specificity; Thalamus; Tissue Distribution | 2013 |
Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation.
Topics: Animals; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Glucose; Heart Function Tests; Hemodynamics; Malates; Male; Membrane Transport Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Rats; Rats, Zucker; Recovery of Function | 2013 |
Brain metabolite changes in patients with type 2 diabetes and cerebral infarction using proton magnetic resonance spectroscopy.
Topics: Aged; Aspartic Acid; Blood Glucose; Brain; Cerebral Infarction; Choline; Creatine; Diabetes Mellitus, Type 2; Female; Humans; Lactic Acid; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons | 2014 |
Type 2 diabetes mellitus: a potentially modifiable risk factor for neurochemical brain changes in bipolar disorders.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Risk Factors | 2015 |
Assessment of changes in brain metabolites in Indian patients with type-2 diabetes mellitus using proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain Chemistry; Choline; Creatinine; Diabetes Mellitus, Type 2; Glucose; Glutamic Acid; Glutamine; Humans; India; Inositol; Magnetic Resonance Spectroscopy; Pilot Projects; Prospective Studies; Protons; Tertiary Care Centers | 2014 |
Brain metabolite alterations demonstrated by proton magnetic resonance spectroscopy in diabetic patients with retinopathy.
Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Corpus Striatum; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diagnostic Techniques, Ophthalmological; Female; Humans; Inositol; Male; Neuroglia; Neurons; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Retina; White Matter | 2014 |
Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.
Topics: Animals; Aspartic Acid; Cell Line; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Glucose; Glycerophosphates; Glycolysis; In Vitro Techniques; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Kinetics; Malates; Male; Membrane Transport Proteins; Metabolome; Mice; Mice, Inbred C3H; Mice, Transgenic; Mitochondria | 2015 |
Hemoglobin A2-Leuven (α2δ2 143(H21) His>Asp): a novel delta-chain variant potentially interfering in hemoglobin A1c measurement using cation exchange HPLC.
Topics: Adult; Aspartic Acid; Cations; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Diabetes Mellitus, Type 2; Female; Genetic Variation; Glycated Hemoglobin; Hematologic Tests; Hemoglobin A2; Histidine; Humans | 2016 |
[Correlation between cognitive impairment and diabetic nephropathy in patients with Type 2 diabetes mellitus].
Topics: Adult; Aspartic Acid; Case-Control Studies; Cerebrum; Choline; Cognition; Cognition Disorders; Creatine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Humans; Neuropsychological Tests | 2016 |
[Hemichorea with Contralateral High Signal Intensity Putaminal Lesion on T1-Weighted Images in Non-Ketotic Hyperglycemia].
Topics: Aspartic Acid; Choline; Chorea; Creatine; Diabetes Complications; Diabetes Mellitus, Type 2; Diffusion Magnetic Resonance Imaging; Dominance, Cerebral; Female; Glycated Hemoglobin; Humans; Hyperglycinemia, Nonketotic; Magnetic Resonance Spectroscopy; Middle Aged; Putamen | 2016 |
Risk for metabolic syndrome predisposes to alterations in the thalamic metabolism.
Topics: Adult; Anthropometry; Aspartic Acid; Blood Glucose; Choline; Creatine; Diabetes Mellitus, Type 2; Humans; Inositol; Insulin; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolic Syndrome; Risk Factors; Thalamus | 2008 |
The Asp298 allele of endothelial nitric oxide synthase is a risk factor for myocardial infarction among patients with type 2 diabetes mellitus.
Topics: Alleles; Aspartic Acid; Data Collection; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nitric Oxide Synthase Type III; Risk Factors | 2008 |
The G1057D polymorphism of IRS-2 gene is not associated with type 2 diabetes and obese patients among ethnic groups in Tunisian population.
Topics: Aspartic Acid; Black People; Diabetes Mellitus, Type 2; Ethnicity; Female; Genetic Predisposition to Disease; Glycine; Humans; Insulin Receptor Substrate Proteins; Male; Middle Aged; Obesity; Polymorphism, Single Nucleotide; Tunisia | 2009 |
MR spectroscopy of cerebral white matter in type 2 diabetes; no association with clinical variables and cognitive performance.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognition; Cognition Disorders; Creatine; Diabetes Mellitus, Type 2; Female; Humans; Magnetic Resonance Spectroscopy; Male; Memory; Middle Aged; Nerve Fibers, Myelinated; Neuropsychological Tests; Photons; Time Factors | 2010 |
Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Brain; Diabetes Mellitus, Type 2; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycogen; Male; Obesity; Rats; Rats, Sprague-Dawley; Rats, Zucker | 2010 |
Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model.
Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Diabetes Mellitus, Type 2; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glycogen; Glycogen Phosphorylase; Homeostasis; Indoles; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phenylbutyrates; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; Rats, Zucker; Synaptic Transmission | 2012 |
In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model.
Topics: Animals; Aspartic Acid; Carbon Isotopes; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucagon; Gluconeogenesis; Insulin Resistance; Liver; Magnetic Resonance Spectroscopy; Malates; Male; Mice; Mice, Inbred C57BL; Pyruvate Carboxylase; Pyruvic Acid | 2013 |
Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes.
Topics: Adult; Aged; Alleles; Aspartic Acid; Cohort Studies; Diabetes Mellitus, Type 2; Fibroblasts; Gene Frequency; Glycine; Heterozygote; Humans; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Leucine; Middle Aged; Phosphoproteins; Polymorphism, Genetic; Valine | 2003 |
Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.
Topics: Adult; Amino Acid Substitution; Animals; Arizona; Aspartic Acid; Base Sequence; Body Composition; Cohort Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; DNA Primers; Glucose Clamp Technique; Glycine; Histidine; Humans; Hyperinsulinism; Indians, North American; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Mice; Obesity; Phosphoproteins; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Regression Analysis | 2003 |
Alterations of cerebral metabolism in patients with diabetes mellitus studied by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Blood Glucose; Brain; Chlorides; Choline; Creatinine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Osmolar Concentration; Potassium; Sodium; Statistics, Nonparametric; Urea | 2003 |
Asp299Gly and Thr399Ile genotypes of the TLR4 gene are associated with a reduced prevalence of diabetic neuropathy in patients with type 2 diabetes.
Topics: Amino Acid Substitution; Aspartic Acid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Genotype; Glycine; Humans; Isoleucine; Membrane Glycoproteins; Mutation, Missense; Odds Ratio; Polymorphism, Single Nucleotide; Prevalence; Receptors, Cell Surface; Threonine; Toll-Like Receptor 4; Toll-Like Receptors; White People | 2004 |
[Study on the association of PPP1R3 gene polymorphism with type 2 diabetes in Han population of Anhui province].
Topics: Adult; Alleles; Aspartic Acid; China; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Obesity; Phosphoprotein Phosphatases; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Protein Phosphatase 1; Risk Factors; Tyrosine | 2004 |
Does the aspartic acid to asparagine substitution at position 76 in the pancreas duodenum homeobox gene (PDX1) cause late-onset type 2 diabetes?
Topics: Age of Onset; Amino Acid Substitution; Asparagine; Aspartic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Europe; Female; Homeodomain Proteins; Humans; Insulin; Male; Mutation, Missense; Pedigree; Trans-Activators; United States; White People | 2004 |
T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study.
Topics: Aged; Albuminuria; Aspartic Acid; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exons; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Homozygote; Humans; Linkage Disequilibrium; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Threonine | 2005 |
Slowly progressing form of type 1 diabetes mellitus in children: genetic analysis compared with other forms of diabetes mellitus in Japanese children.
Topics: Age of Onset; Arginine; Asian People; Aspartic Acid; Autoantibodies; Case-Control Studies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Progression; Female; Gene Frequency; Genotype; Haplotypes; Humans; Japan; Male; Phenotype | 2005 |
Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Choline; Creatine; Depressive Disorder, Major; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales | 2007 |
Frequency and significance of the novel single nucleotide missense polymorphism Val109Asp in the human gene encoding omentin in Caucasian patients with type 2 diabetes mellitus or chronic inflammatory bowel diseases.
Topics: Amino Acid Substitution; Aspartic Acid; Chronic Disease; Cohort Studies; Cytokines; Diabetes Mellitus, Type 2; Female; Gene Frequency; GPI-Linked Proteins; Humans; Inflammatory Bowel Diseases; Lectins; Male; Mutation, Missense; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Reference Values; Valine; White People | 2007 |
Assessment of the metabolic profile in Type 2 diabetes mellitus and hypothyroidism through proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Diabetes Mellitus, Type 2; Female; Humans; Hypothyroidism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Signal Processing, Computer-Assisted | 2008 |
Asp905Tyr polymorphism of the gene for the skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in NIDDM.
Topics: Adult; Aged; Alleles; Amino Acid Substitution; Aspartic Acid; Body Mass Index; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genes; Genotype; Glycogen; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Muscle, Skeletal; Phosphoprotein Phosphatases; Polymorphism, Genetic; Protein Phosphatase 1; Tyrosine | 1998 |
Mutations in HFE, the hemochromatosis candidate gene, in patients with NIDDM.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Major Histocompatibility Complex; Membrane Proteins; Point Mutation; Reference Values; Tyrosine | 1998 |
Hemoglobin Rambam (beta69[E13]Gly-->Asp), a pitfall in the assessment of diabetic control: characterization by electrospray mass spectrometry and HPLC.
Topics: Amino Acid Sequence; Aspartic Acid; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; DNA; Female; Glycated Hemoglobin; Glycine; Humans; Lung Diseases, Obstructive; Mass Spectrometry; Middle Aged; Molecular Sequence Data; Oxygen; Point Mutation | 1998 |
A common Glu298-->Asp (894G-->T) mutation at exon 7 of the endothelial nitric oxide synthase gene and vascular complications in type 2 diabetes.
Topics: Albuminuria; Amino Acid Substitution; Angina Pectoris; Aspartic Acid; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Exons; Genotype; Glutamic Acid; Humans; Middle Aged; Myocardial Infarction; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peripheral Vascular Diseases; Point Mutation; Risk Factors | 1998 |
The 3'-untranslated region polymorphism of the gene for skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in the type 2 diabetic Japanese population.
Topics: 3' Untranslated Regions; Alleles; Aspartic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genotype; Humans; Japan; Male; Middle Aged; Phosphoprotein Phosphatases; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Protein Phosphatase 1 | 1999 |
Evidence of enhancement of malate-aspartate shuttle activity in beta cells of streptozotocin-induced non-insulin-dependent diabetic rats.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Insulin; Islets of Langerhans; Malates; Male; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley | 2000 |
Clinical characteristics of type 2 diabetes in patients with mutations of HFE.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Female; Ferritins; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Insulin Resistance; Iron; Major Histocompatibility Complex; Male; Membrane Proteins; Middle Aged; Point Mutation; Transferrin; Tyrosine | 2000 |
Aspartame metabolism in normal adults, phenylketonuric heterozygotes, and diabetic subjects.
Topics: Adult; Aspartame; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Erythrocytes; Female; Glucagon; Heterozygote; Humans; Insulin; Lipids; Male; Methanol; Phenylalanine; Phenylketonurias; Reference Values | 1989 |
Diet effects on membrane phospholipid fatty acids and mitochondrial function in BHE rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Aspartic Acid; Coconut Oil; Corn Oil; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Acids; Glycerophosphates; Malates; Male; Membrane Lipids; Mitochondria, Liver; NAD; Oils; Phospholipids; Plant Oils; Rats; Rats, Mutant Strains | 1986 |