Page last updated: 2024-11-08

aspartic acid and Demyelinating Diseases

aspartic acid has been researched along with Demyelinating Diseases in 42 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.

Research Excerpts

ExcerptRelevanceReference
"Citrulline was more frequently identified in the brains of patients with early-onset MS than in healthy subjects by (1)H-MR spectroscopy, suggesting an association of increased citrullination of myelin proteins with demyelinating diseases."5.14Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis. ( Aksu, AO; Anlar, B; Haspolat, S; Karabulut, E; Kurne, A; Kurul, S; Oguz, KK; Senbil, N; Serdaroglu, A; Teber, S, 2009)
"The inherited leukodystrophy Canavan disease arises due to a loss of the ability to catabolize N-acetylaspartic acid (NAA) in the brain and constitutes a major point of focus for efforts to define NAA function."3.78Aspartoacylase supports oxidative energy metabolism during myelination. ( Francis, JS; Leone, P; Markov, V; Strande, L, 2012)
" Strongly elevated concentrations of myo-inositol in conjunction with normal or increased choline-containing compounds in all regions investigated point to astrocytosis and demyelination."3.72Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease. ( Brockmann, K; Dechent, P; Frahm, J; Hanefeld, F; Haupt, M; Meins, M; Sperner, J; Stephani, U, 2003)
"Eight patients with advanced breast cancer were entered into a prospective, longitudinal trial that included examination by MR imaging and proton MR spectroscopy before chemotherapy and through 12 months after treatment with carmustine, cyclophosphamide, and cisplatin, combined with autologous hematopoietic progenitor cell support (AHPCS)."3.70White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. ( Brown, MS; Cagnoni, PJ; Jones, RB; Sheeder, JL; Simon, JH; Stears, JC; Stemmer, SM, 1998)
"Epilepsy is too complex to be considered as a disease; it is more of a syndrome, characterized by seizures, which can be caused by a diverse array of afflictions."2.55Control of seizures by ketogenic diet-induced modulation of metabolic pathways. ( Akabani, G; Aramayo, R; Clanton, RM; Wu, G, 2017)
"Our results suggest that demyelination plays an important role in WM disruption post-injury in a subgroup of msTBI children and indicate the utility of multi-modal imaging."1.48Magnetic resonance spectroscopy of fiber tracts in children with traumatic brain injury: A combined MRS - Diffusion MRI study. ( Alger, J; Asarnow, RF; Babbitt, C; Babikian, T; Dennis, EL; Giza, CC; Jin, Y; Johnson, J; Mink, R; Olsen, A; Rashid, F; Thompson, PM; Villalon-Reina, JE, 2018)
"Ovarian teratoma was detected and resected in only one case of initial episode."1.42[Clinical analysis of relapsing anti-N-methyl-D-aspartate receptor encephalitis]. ( Bin, P; Dawei, S; Haitao, R; Hang, S; Hongzhi, G; Liying, C; Qiang, L; Qing, L; Weize, K; Yan, H; Yicheng, Z; Yuan, J, 2015)
"Tumefactive demyelination (TD) is a relatively uncommon entity which mimics other focal intracranial lesions."1.37Conventional and advanced magnetic resonance imaging in tumefactive demyelination. ( Chatterjee, S; Kesavadas, C; Saini, J; Thomas, B, 2011)
"Active demyelination or increased myelin turnover might contribute to the hitherto unexplained WMD of this rare disorder."1.33White-matter disease in 18q deletion (18q-) syndrome: magnetic resonance spectroscopy indicates demyelination or increased myelin turnover rather than dysmyelination. ( Anhuf, D; Häusler, M; Möller-Hartmann, W; Ramaekers, VT; Schüler, H; Thron, A; Zerres, K, 2005)
"A Cho elevation may precede visible demyelination on T2-weighted images."1.30The value of new MRI techniques in adrenoleukodystrophy. ( Engelbrecht, V; Gärtner, J; Kahn, T; Mödder, U; Rassek, M, 1997)
"MR studies of these infants showed obstructive hydrocephalus caused by mass effect produced by an enlarged cerebellum."1.30Imaging studies in a unique familial dysmyelinating disorder. ( Duhaime, AC; Gripp, KW; Molloy, PT; Muenke, M; Rorke, LB; Schut, L; Tucker, SH; Wang, ZJ; Zackai, EH; Zimmerman, RA, 1998)
"The mechanisms behind the demyelination that is characteristic of multiple sclerosis (MS) are still poorly understood."1.30Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy. ( Bitsch, A; Brück, W; Bruhn, H; Frahm, J; Lassmann, H; Stringaris, A; Vougioukas, V, 1999)
"The two patients with MELAS syndrome had large decreases of NAA signal (50% and 20% of normal values, respectively) from their occipital lobe lesions during the acute stroke-like episodes."1.29Reversible decreases in N-acetylaspartate after acute brain injury. ( Arnold, DL; De Stefano, N; Matthews, PM, 1995)
"Despite regional variability of demyelination, proton magnetic resonance spectroscopy revealed a specific metabolic pattern in all patients, with only moderate reduction of N-acetylaspartate, normal or reduced choline-containing compounds, normal or enhanced myo-inositol and no detectable lactate, which differs from findings in progressive cerebral adrenoleukodystrophy which usually exhibits a severe reduction of N-acetylaspartate and marked increases of choline-containing compounds, myo-inositol, and lactate."1.29Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients. ( Frahm, J; Hanefeld, F; Hunneman, DH; Jost, W; Korenke, GC; Krasemann, E; Pouwels, PJ; Stoeckler, S, 1996)
"Four grades of demyelination and three grades of cerebral atrophy were distinguished by magnetic resonance imaging criteria."1.281H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders. ( den Hollander, JA; Luyten, PR; Nauta, JJ; Valk, J; van der Grond, J; van der Knaap, MS, 1992)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.76)18.7374
1990's16 (38.10)18.2507
2000's11 (26.19)29.6817
2010's13 (30.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dennis, EL1
Babikian, T1
Alger, J1
Rashid, F1
Villalon-Reina, JE1
Jin, Y1
Olsen, A1
Mink, R1
Babbitt, C1
Johnson, J1
Giza, CC1
Thompson, PM1
Asarnow, RF1
Lu, SS1
Kim, SJ1
Kim, HS2
Choi, CG1
Lim, YM1
Kim, EJ1
Kim, DY1
Cho, SH1
Nave, KA1
Werner, HB1
Praet, J1
Orije, J1
Kara, F1
Guglielmetti, C1
Santermans, E1
Daans, J1
Hens, N1
Verhoye, M1
Berneman, Z1
Ponsaerts, P1
Van der Linden, A1
Takanashi, J1
Wootla, B1
Denic, A2
Watzlawik, JO1
Warrington, AE1
Rodriguez, M2
Hongzhi, G1
Weize, K1
Bin, P1
Yan, H1
Qiang, L1
Yuan, J1
Qing, L1
Hang, S1
Haitao, R1
Yicheng, Z1
Dawei, S1
Liying, C1
Clanton, RM1
Wu, G1
Akabani, G1
Aramayo, R1
Oguz, KK1
Kurne, A1
Aksu, AO1
Karabulut, E1
Serdaroglu, A1
Teber, S1
Haspolat, S1
Senbil, N1
Kurul, S1
Anlar, B1
Machado, A1
Soares-Fernandes, J1
Ribeiro, M1
Rodrigues, M1
Cerqueira, J1
Ferreira, C1
Bieber, A1
Warrington, A1
Mishra, PK1
Macura, S1
Sohn, SY1
Ko, YJ1
Hong, JM1
Kim, SH1
Kim, JH1
Chi, JG1
Moon, SY1
Saini, J1
Chatterjee, S1
Thomas, B1
Kesavadas, C1
Francis, JS1
Strande, L1
Markov, V1
Leone, P1
Khalil, M1
Enzinger, C1
Langkammer, C1
Ropele, S1
Mader, A1
Trentini, A1
Vane, ML1
Wallner-Blazek, M1
Bachmaier, G1
Archelos, JJ1
Koel-Simmelink, MJ1
Blankenstein, MA1
Fuchs, S1
Fazekas, F1
Teunissen, CE1
Tajima, Y1
Mito, Y1
Yanai, M1
Fukazawa, Y1
Saindane, AM1
Cha, S1
Law, M1
Xue, X1
Knopp, EA1
Zagzag, D1
Brockmann, K1
Dechent, P1
Meins, M1
Haupt, M1
Sperner, J1
Stephani, U1
Frahm, J3
Hanefeld, F2
Häusler, M1
Anhuf, D1
Schüler, H1
Ramaekers, VT1
Thron, A1
Zerres, K1
Möller-Hartmann, W1
Porto, L1
Hattingen, E1
Pilatus, U1
Kieslich, M1
Yan, B1
Schwabe, D1
Zanella, FE1
Lanfermann, H1
Cianfoni, A1
Niku, S1
Imbesi, SG1
Hiehle, JF1
Lenkinski, RE2
Grossman, RI2
Dousset, V1
Ramer, KN1
Schnall, MD1
Cohen, JA1
Gonzalez-Scarano, F2
Hájek, M1
Hejcmanová, L1
Prádný, J1
De Stefano, N2
Matthews, PM3
Antel, JP2
Preul, M1
Francis, G1
Arnold, DL3
Confort-Gouny, S1
Vion-Dury, J1
Chabrol, B1
Nicoli, F1
Cozzone, PJ1
Kimura, H1
Korenke, GC1
Pouwels, PJ2
Hunneman, DH1
Stoeckler, S1
Krasemann, E1
Jost, W1
Engelbrecht, V1
Rassek, M1
Gärtner, J1
Kahn, T1
Mödder, U1
Brown, MS1
Stemmer, SM1
Simon, JH1
Stears, JC1
Jones, RB1
Cagnoni, PJ1
Sheeder, JL1
Gripp, KW1
Zimmerman, RA2
Wang, ZJ1
Rorke, LB1
Duhaime, AC1
Schut, L1
Molloy, PT1
Tucker, SH1
Zackai, EH1
Muenke, M1
Bitsch, A1
Bruhn, H1
Vougioukas, V1
Stringaris, A1
Lassmann, H1
Brück, W1
Davie, CA1
Silver, NC1
Barker, GJ1
Tofts, PS1
Thompson, AJ1
McDonald, WI1
Miller, DH1
van der Knaap, MS2
Wevers, RA1
Struys, EA1
Verhoeven, NM1
Engelke, UF1
Feikema, W1
Valk, J2
Jakobs, C1
Blüml, S1
Hwang, JH1
Moreno, A1
Ross, BD1
Pozdniakov, AV1
Tiutin, LA1
Bisaga, GN1
Odinak, MM1
Espay, AJ1
Bodensteiner, JB1
Patel, H1
van der Grond, J1
Luyten, PR1
den Hollander, JA1
Nauta, JJ1
Francis, GS1
O'Connor, J1
Marks, HG1
Caro, PA1
Wang, ZY1
Detre, JA1
Bogdan, AR1
Gusnard, DA1
Elpeleg, ON1
Amir, N1
Glick, B1
Gross-Tzur, V1
Zelnik, N1
Tamiri, Z1
Gay, C1
Divry, P1
Macabeo, V1
Dumont, C1
Gilly, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Clinical Features of Combined Central and Peripheral Demyelination[NCT04664647]30 participants (Anticipated)Observational2020-12-31Not yet recruiting
Mapping the Natural History of Traumatic Spinal Cord Injury in the Sensorimotor Cortex Using Functional Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging[NCT00790361]20 participants (Actual)Observational2009-06-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for aspartic acid and Demyelinating Diseases

ArticleYear
Myelination of the nervous system: mechanisms and functions.
    Annual review of cell and developmental biology, 2014, Volume: 30

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Axons; Central Nervous System; Charcot-Marie-Tooth D

2014
Neurochemistry of Hypomyelination Investigated with MR Spectroscopy.
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2015, Volume: 14, Issue:2

    Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Demyelinating Diseases; Disease Models,

2015
Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease.
    Molecular neurobiology, 2016, Volume: 53, Issue:8

    Topics: Animals; Antibodies; Aspartic Acid; Axons; Brain Stem; Cardiovirus Infections; Demyelinating Disease

2016
Control of seizures by ketogenic diet-induced modulation of metabolic pathways.
    Amino acids, 2017, Volume: 49, Issue:1

    Topics: Amino Acids, Essential; Aspartic Acid; Demyelinating Diseases; Diet, Ketogenic; Epilepsy; Fatty Acid

2017

Trials

1 trial available for aspartic acid and Demyelinating Diseases

ArticleYear
Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis.
    AJNR. American journal of neuroradiology, 2009, Volume: 30, Issue:4

    Topics: Adolescent; Age of Onset; Aspartic Acid; Child; Child, Preschool; Choline; Citrulline; Creatine; Dem

2009

Other Studies

37 other studies available for aspartic acid and Demyelinating Diseases

ArticleYear
Magnetic resonance spectroscopy of fiber tracts in children with traumatic brain injury: A combined MRS - Diffusion MRI study.
    Human brain mapping, 2018, Volume: 39, Issue:9

    Topics: Adolescent; Anisotropy; Aspartic Acid; Brain Damage, Chronic; Brain Injuries, Traumatic; Child; Chol

2018
Utility of proton MR spectroscopy for differentiating typical and atypical primary central nervous system lymphomas from tumefactive demyelinating lesions.
    AJNR. American journal of neuroradiology, 2014, Volume: 35, Issue:2

    Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Demyelinating Diseases; Diagnosis, Differential

2014
Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra.
    NMR in biomedicine, 2015, Volume: 28, Issue:4

    Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Cuprizone; Demyelinating Diseases; Dipep

2015
[Clinical analysis of relapsing anti-N-methyl-D-aspartate receptor encephalitis].
    Zhonghua yi xue za zhi, 2015, Apr-07, Volume: 95, Issue:13

    Topics: Adolescent; Adult; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Aspartic Acid; Autoantibodies; B

2015
Alcohol abuse and acute behavioural disturbances in a 24-year-old patient. Diagnosis: Marchiafava-Bignami disease (MBD).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009, Volume: 16, Issue:6

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Aspartic Acid; Choline; Corpus Callosum; Crea

2009
Brainstem 1H nuclear magnetic resonance (NMR) spectroscopy: marker of demyelination and repair in spinal cord.
    Annals of neurology, 2009, Volume: 66, Issue:4

    Topics: Animals; Aspartic Acid; Biomarkers; Brain Stem; Demyelinating Diseases; Friend murine leukemia virus

2009
A case of pigmentary orthochromatic leukodystrophy with findings of proton MR spectroscopy and serial brain MRIs.
    Journal of the neurological sciences, 2010, Aug-15, Volume: 295, Issue:1-2

    Topics: Adult; Antigens, CD; Aspartic Acid; Brain; Brain Diseases; Brain Mapping; Creatine; Demyelinating Di

2010
Conventional and advanced magnetic resonance imaging in tumefactive demyelination.
    Acta radiologica (Stockholm, Sweden : 1987), 2011, Dec-01, Volume: 52, Issue:10

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Contrast Media; Demyelinatin

2011
Aspartoacylase supports oxidative energy metabolism during myelination.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:9

    Topics: Amidohydrolases; Animals; Aspartic Acid; Biomarkers; Canavan Disease; Cells, Cultured; Chromatograph

2012
CSF neurofilament and N-acetylaspartate related brain changes in clinically isolated syndrome.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2013, Volume: 19, Issue:4

    Topics: Adult; Aspartic Acid; Biomarkers; Brain; Demyelinating Diseases; Female; Humans; Magnetic Resonance

2013
Unusual basal ganglia lesions in a diabetic uraemic patient proven to be demyelination: first pathological observation.
    BMJ case reports, 2012, Sep-03, Volume: 2012

    Topics: Aspartic Acid; Basal Ganglia; Basal Ganglia Diseases; Demyelinating Diseases; Diabetic Nephropathies

2012
Proton MR spectroscopy of tumefactive demyelinating lesions.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:8

    Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Demyelinating Diseases; Diagnosis, Different

2002
Cerebral proton magnetic resonance spectroscopy in infantile Alexander disease.
    Journal of neurology, 2003, Volume: 250, Issue:3

    Topics: Alexander Disease; Aspartic Acid; Brain; Child; Child, Preschool; Demyelinating Diseases; Disease Pr

2003
White-matter disease in 18q deletion (18q-) syndrome: magnetic resonance spectroscopy indicates demyelination or increased myelin turnover rather than dysmyelination.
    Neuroradiology, 2005, Volume: 47, Issue:1

    Topics: Aspartic Acid; Brain Diseases; Choline; Chromosome Deletion; Chromosomes, Human, Pair 18; Demyelinat

2005
Proton magnetic resonance spectroscopy in childhood brainstem lesions.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2007, Volume: 23, Issue:3

    Topics: Adolescent; Amino Acids; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Stem; Brain Stem Neop

2007
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases;

2007
Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis.
    Magnetic resonance in medicine, 1994, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Choline; Cohort Studies; Creatine; Demyelinating Dise

1994
Proton in vivo spectroscopy of patients with hyperphenylalaninaemia.
    Neuropediatrics, 1993, Volume: 24, Issue:2

    Topics: Adult; Aspartic Acid; Biopterins; Brain; Brain Chemistry; Brain Diseases; Child; Choline; Creatine;

1993
Chemical pathology of acute demyelinating lesions and its correlation with disability.
    Annals of neurology, 1995, Volume: 38, Issue:6

    Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Demyelinating Diseases; Disability Evaluation; Femal

1995
Reversible decreases in N-acetylaspartate after acute brain injury.
    Magnetic resonance in medicine, 1995, Volume: 34, Issue:5

    Topics: Acute Disease; Aspartic Acid; Brain; Demyelinating Diseases; Humans; Magnetic Resonance Spectroscopy

1995
Localised proton magnetic resonance spectroscopy in X-linked adrenoleukodystrophy.
    Neuroradiology, 1995, Volume: 37, Issue:7

    Topics: Adolescent; Adrenoleukodystrophy; Adult; Aspartic Acid; Brain; Child; Creatine; Demyelinating Diseas

1995
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:8

    Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel

1996
Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients.
    Pediatric neurology, 1996, Volume: 15, Issue:2

    Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic; Child; Choline; Demyelinating Diseases; Female; Hum

1996
The value of new MRI techniques in adrenoleukodystrophy.
    Pediatric radiology, 1997, Volume: 27, Issue:3

    Topics: Adolescent; Adrenoleukodystrophy; Aspartic Acid; Brain; Child; Child, Preschool; Choline; Demyelinat

1997
White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain; Brain Diseases; B

1998
Imaging studies in a unique familial dysmyelinating disorder.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:7

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Canavan Disease; Cerebellar Diseases; Cerebral Cortex; Chol

1998
Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy.
    AJNR. American journal of neuroradiology, 1999, Volume: 20, Issue:9

    Topics: Adult; Aspartic Acid; Axons; Biopsy, Needle; Blood-Brain Barrier; Brain; Cell Division; Choline; Dem

1999
Does the extent of axonal loss and demyelination from chronic lesions in multiple sclerosis correlate with the clinical subgroup?
    Journal of neurology, neurosurgery, and psychiatry, 1999, Volume: 67, Issue:6

    Topics: Aspartic Acid; Axons; Cerebral Cortex; Chronic Disease; Demyelinating Diseases; Disease Progression;

1999
Leukoencephalopathy associated with a disturbance in the metabolism of polyols.
    Annals of neurology, 1999, Volume: 46, Issue:6

    Topics: Adolescent; Aspartic Acid; Carbohydrate Metabolism, Inborn Errors; Choline; Creatine; Demyelinating

1999
Novel peak assignments of in vivo (13)C MRS in human brain at 1.5 T.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2000, Volume: 143, Issue:2

    Topics: Adult; Aspartic Acid; Bicarbonates; Brain; Carbon Isotopes; Child, Preschool; Creatine; Demyelinatin

2000
[Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Demyelinating Diseases; Female; gamma-Am

2001
Episodic coma in a new leukodystrophy.
    Pediatric neurology, 2002, Volume: 26, Issue:2

    Topics: Aspartic Acid; Ataxia; Brain; Child; Choline; Coma; Creatine; Demyelinating Diseases; Epilepsy, Post

2002
1H and 31P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders.
    Annals of neurology, 1992, Volume: 31, Issue:2

    Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Child; Creatine; Demyelinating Diseases; Human

1992
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques.
    Annals of neurology, 1992, Volume: 31, Issue:3

    Topics: Acute Disease; Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; De

1992
Use of computed tomography, magnetic resonance imaging, and localized 1H magnetic resonance spectroscopy in Canavan's disease: a case report.
    Annals of neurology, 1991, Volume: 30, Issue:1

    Topics: Amidohydrolases; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain Diseases, Metabolic; Chi

1991
[Organic aciduria in Canavan disease].
    Harefuah, 1989, Dec-01, Volume: 117, Issue:11

    Topics: Acids; Aspartic Acid; Demyelinating Diseases; Female; Humans; Infant; Lipidoses; Male

1989
[N-acetylaspartic aciduria: a new form of demyelinating encephalopathy].
    Presse medicale (Paris, France : 1983), 1988, Jan-30, Volume: 17, Issue:3

    Topics: Acids; Aspartic Acid; Consanguinity; Demyelinating Diseases; Encephalitis; Humans

1988