aspartic acid has been researched along with Dementia Praecox in 226 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.33) | 18.7374 |
| 1990's | 40 (17.70) | 18.2507 |
| 2000's | 88 (38.94) | 29.6817 |
| 2010's | 77 (34.07) | 24.3611 |
| 2020's | 18 (7.96) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; He, Y; Ma, X; Ouyang, L; Yuan, L; Zheng, W | 1 |
| Carter, CS; Maddock, RJ; Smucny, J | 1 |
| Javitt, DC; Kantrowitz, JT | 1 |
| Chen, X; Dai, L; Dong, M; He, J; He, Y; Li, C; Li, H; Li, J; Li, Z; Liao, Y; Liu, T; O'Neill, J; Ren, H; Tang, J; Wang, Q; Zhou, J | 1 |
| Chen, YY; Chou, YH; Liu, MN; Yang, BH; Yang, KC | 1 |
| Altynbekov, KS; Asadullin, AR; Gayduk, AJ; Khasanova, AK; Markina, EA; Nasyrova, RF; Petrova, MM; Shipulin, GA; Shnayder, NA | 1 |
| Chen, X; Dai, L; Dong, M; He, J; He, Y; Li, C; Li, J; Li, Z; Liao, Y; Ren, H; Tang, J; Wang, Q; Zhou, J | 1 |
| Maddock, RJ; Smucny, J; Yang, YS; Zhang, H | 1 |
| Dechent, P; Ertl-Wagner, B; Falkai, P; Ghaseminejad, F; Hasan, A; Helms, G; Karali, T; Keeser, D; Keller-Varady, K; Malchow, B; Maurus, I; Rauchmann, BS; Schmitt, A; Schneider-Axmann, T; Takahashi, S; Wobrock, T | 1 |
| Benyamina, A; Martelli, C; Petillion, A; Romeo, B | 1 |
| Bustillo, JR; Gasparovic, C; Jones, T; Lenroot, R; Maudsley, AA; Mayer, EG; Tohen, M; Upston, J | 1 |
| Horita, N; Kubota, M; Moriguchi, S; Nakajima, S; Takahata, K | 1 |
| Haring, L; Kangro, R; Koch, K; Leppik, L; Parksepp, M; Uppin, K; Vasar, E; Zilmer, M | 1 |
| Bryll, A; Karcz, P; Kozicz, T; Krzyściak, W; Pilecki, M; Popiela, TJ; Skrzypek, J; Śmierciak, N; Szwajca, M | 1 |
| Howes, O; Onwordi, EC; Osugo, M; Shatalina, E; Townsend, L; Vava, R; Whitehurst, TS | 1 |
| Gonen, O; Kranz, TM; Lotan, E; Malaspina, D; Perez, SA; Rusinek, H; Walsh-Messinger, J | 1 |
| Geissah, S; Intson, K; McCullumsmith, RE; Ramsey, AJ | 1 |
| Alon, A; Kruse, AC; Martin, SF; Sahn, JJ; Schmidt, HR; Wood, MD | 1 |
| Denney, TS; Gawne, TJ; Lahti, AC; Reid, MA; Salibi, N; White, DM | 1 |
| Alshehri, Y; Caravaggio, F; Chakravarty, MM; Chavez, S; Chung, JK; De Luca, V; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Kim, J; Nakajima, S; Plitman, E; Remington, G | 1 |
| Bation, R; Brunelin, J; Fonteneau, C; Haesebaert, F; Mondino, M; Psomiades, M; Suaud-Chagny, MF | 1 |
| Caravaggio, F; Chung, JK; Gerretsen, P; Graff-Guerrero, A; Iwata, Y; Kim, J; Mihashi, Y; Mimura, M; Nakajima, S; Plitman, E; Remington, G | 1 |
| Brookes, MJ; Christodoulou, NG; Fernandes, CC; Fiesal, J; Hall, EL; Katshu, MZ; Kumar, J; Liddle, EB; Liddle, PF; Morris, PG; Palaniyappan, L; Qureshi, A; Robson, SE; Simmonite, M; Skelton, M | 1 |
| Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E | 1 |
| Gonzales, SS; Kraguljac, NV; Lahti, AC; Morgan, CJ; Sivaraman, S; White, DM | 1 |
| Dwyer, GE; Grüner, R; Hugdahl, K; Specht, K | 1 |
| Bustillo, JR; Chavez, L; Gasparovic, C; Jones, T; Lenroot, RK; Lin, D; Qualls, C | 1 |
| Chen, X; Du, F; Fan, X; Huynh, P; Lewandowski, KE; Öngür, D | 1 |
| Avsar, KB; den Hollander, JA; Kraguljac, NV; Lahti, AC; Reid, MA; White, DM | 1 |
| Bracken, BK; Olson, DP; Renshaw, PF; Rouse, ED | 1 |
| Bolo, NR; Francis, AN; Keshavan, MS; Mathew, IT; Sanghavi, K; Stanley, JA; Tandon, N | 1 |
| Bertolino, A; Blasi, G; D'Aniello, A; de Bartolomeis, A; Errico, F; Napolitano, F; Squillace, M; Usiello, A; Vitucci, D | 1 |
| Alafaci, C; Granata, F; Longo, M; Morabito, R; Pandolfo, G; Pitrone, A; Settineri, N; Vinci, S | 1 |
| Demjaha, A; Egerton, A; Howes, OD; Kapur, S; McGuire, PK; Murray, RM; Stone, JM | 1 |
| Abe, O; Aoki, Y; Gonoi, W; Inoue, H; Iwashiro, N; Kasai, K; Katsura, M; Koike, S; Natsubori, T; Sasaki, H; Takano, Y; Takao, H; Yahata, N; Yamasue, H | 1 |
| Falkai, P; Gruber, O; Hasan, A; Jatzko, A; Malchow, B; Schmitt, A; Schneider-Axmann, T; Wobrock, T | 1 |
| Kraguljac, NV; Lahti, AC; Reid, MA; White, DM | 2 |
| Boesch, C; Dierks, T; Federspiel, A; Homan, P; Hubl, D; Kreis, R; Strik, W; Van Swam, C; Vermathen, P | 1 |
| Cheng, ZX; Duan, HF; Gan, JL; Gao, CY; Yang, JM; Zhu, XQ | 1 |
| Bernier, DC; Crocker, CE; Hanstock, CC; Lakusta, B; Purdon, SE; Seres, P; Tibbo, PG | 1 |
| Bartko, JJ; Choi, C; Ghose, S; Hulsey, K; Mihalakos, P; Morris, SU; Stan, AD; Tamminga, CA; Yanagi, M; Zhao, C | 1 |
| Aguilar, EJ; Celda, B; Marti-Bonmati, L; Martinez-Bisbal, MC; Martinez-Granados, B; Molla, E; Sanjuan, J | 1 |
| Andreychenko, A; Boer, VO; Bohlken, MM; Cahn, W; Hulshoff Pol, HE; Kahn, RS; Klomp, DW; Luijten, PR; Mandl, RC; Marsman, A | 1 |
| Algın, O; Atagün, MI; Can, SS; Çayköylü, A; Karakaş-Uğurlu, G; Moore, CM; Öngür, D; Phillips, ML; Şıkoğlu, EM; Ulusoy-Kaymak, S | 1 |
| Barker, PB; Bonekamp, S; Coughlin, JM; Edden, RA; Higgs, C; Kim, PK; Marsman, A; Pomper, M; Sawa, A; Schretlen, D; Tanaka, T; Varvaris, M; Wang, H | 1 |
| Cao, H; Chen, X; He, Y; Hu, M; Li, Z; Liao, Y; Lv, L; Sang, D; Tang, J; Zhao, H; Zhou, J; Zong, X | 1 |
| Akhadov, TA; Lebedeva, IS; Lukovkina, OV; Semenova, NA; Sidorin, SV; Ublinskii, MV | 1 |
| Abbott, C; Bustillo, JR; Canive, J; Caprihan, A; Chen, H; Gasparovic, C; Jones, T; Lemke, N; Qualls, C | 1 |
| Goetz, R; Gonen, O; Lazar, M; Malaspina, D; Mazgaj, R; Messinger, JW; Rothman, K; Tal, A | 1 |
| Chiappelli, J; Du, X; Gaston, F; Hong, LE; Kochunov, P; Rowland, LM; Wijtenburg, SA | 1 |
| Amminger, GP; Basu, S; Dietzek, M; Gaser, C; Gussew, A; Lorenz, C; Maitra, R; McGorry, P; Nenadic, I; Reichenbach, JR; Sauer, H; Schönfeld, N; Smesny, S | 1 |
| Jiang, B; Li, H; Liu, W; Pan, B; Yu, H; Yu, S; Zheng, L | 1 |
| Amminger, P; Biesel, NJ; Gaser, C; Gussew, A; Hipler, UC; Milleit, B; Reichenbach, JR; Rzanny, R; Sauer, H; Schack, S; Schultz, CC; Smesny, S; Sobanski, T; Walther, M | 1 |
| Gawlik-Kotelnicka, O; Gmitrowicz, A; Grzelak, P; Kałużyńska, O; Kotlicka-Antczak, M; Podgórski, M; Stefańczyk, L; Strzelecki, D | 1 |
| Chavez, S; de la Fuente-Sandoval, C; Gómez-Cruz, G; Graff-Guerrero, A; León-Ortiz, P; Plitman, E; Reyes-Madrigal, F | 1 |
| Barker, PB; Brandt, AS; Churchill, G; Edden, RA; Harris, AD; Hua, J; Lim, IA; Margolis, RL; Pradhan, S; Ross, CA; Unschuld, PG; van Zijl, PC | 1 |
| Antonius, D; Berns, A; Chao, MV; Goetz, R; Gonen, O; Harroch, S; Hasan, S; Heguy, A; Kranz, TM; Lazar, M; Malaspina, D; Mazgaj, R; Rothman, K | 1 |
| Babb, JS; Davitz, MS; Gonen, O; Kirov, II; Lazar, M; Malaspina, D; Meyer, EJ; Tal, A | 1 |
| Abbott, C; Bustillo, JR; Canive, J; Chen, H; Gasparovic, C; Jones, T; Lemke, N; Qualls, C; Stromberg, S | 1 |
| Cheng, ZX; Duan, HF; Gan, JL; Gao, CY; Liang, XJ; Yang, JM; Zhao, LM; Zhu, XQ | 1 |
| Browne, A; Deicken, RF; Fu, Y; Jakary, A; Vinogradov, S | 1 |
| Gilat, Y; Gross-Isseroff, R; Hermesh, H; Kushnir, T; Manor, D; Munitz, H; Shiloh, R; Stryjer, R; Weizman, A | 1 |
| Cohen, BM; Jensen, JE; Lundy, M; Öngür, D; Prescot, AP; Renshaw, PF; Stork, C | 1 |
| Cannon, TD; Huttunen, MO; Kaprio, J; Lönnqvist, J; Lutkenhoff, ES; Manninen, M; O'Neill, J; Therman, S; Thomas, MA; van Erp, TG | 1 |
| Aguilar, EJ; Brotons, O; Celda, B; González, JC; Martí-Bonmati, L; Martínez-Bisbal, MC; Martínez-Granados, B; Sanjuán, J | 1 |
| Backens, M; Bondy, B; Falkai, P; Gruber, O; Möller, HJ; Reith, W; Scherk, H; Schneider-Axmann, T; Usher, J; Wobrock, T; Zill, P | 1 |
| Arolt, V; Bauer, J; Kölkebeck, K; Kugel, H; Ohrmann, P; Pedersen, A; Rothermundt, M; Siegmund, A; Suslow, T; Wiedl, KH | 1 |
| Harada, M; Iga, J; Nakataki, M; Numata, S; Ohmori, T; Shibuya-Tayoshi, S; Sumitani, S; Taniguchi, K; Tayoshi, S; Ueno, S | 1 |
| Araújo, D; Crippa, JA; de Sousa, JP; Hallak, JE; Sanches, RF; Santos, AC; Zuardi, AW | 1 |
| Choi, CH; Choi, JS; Jang, DP; Jung, WH; Kang, DH; Kwon, JS; Lee, JM; Shin, NY; Yeon, S; Yoo, SY | 1 |
| Chang, HM; Guo, ZW; Qi, ST; Wang, H; Wang, KW; Yang, KJ | 1 |
| Ende, G; Hoerst, M; Meyer-Lindenberg, A; Tunc-Skarka, N; Weber-Fahr, W; Zink, M | 1 |
| Dick, RM; Diwadkar, VA; Keshavan, MS; Montrose, DM; Prasad, KM; Stanley, JA | 1 |
| Baker, GB; Barger, SW; Labrie, V; Roder, JC; Wang, W | 1 |
| Brooks, WM; Bustillo, JR; Chen, H; Hammond, R; Jung, R; Lauriello, J; Mullins, P; Qualls, C; Rowland, LM | 1 |
| Cohen, BM; Jensen, JE; Olson, DP; Ongür, D; Prescot, AP; Renshaw, PF; Rouse, ED | 1 |
| Blau, C; Fagan, AJ; Harte, M; Harvey, RP; Kerskens, C; Lai, D; O'Leary, C; O'Sullivan, GJ; O'Tuathaigh, CM; Reynolds, GP; Tighe, O; Waddington, JL | 1 |
| Backens, M; Berner, D; Falkai, P; Gruber, O; Honer, WG; Kaizl, I; Kierer, A; Meyer, T; Müller, S; Oest, M; Pajonk, FG; Scherk, H; Schneider-Axmann, T; Thornton, AE; Wobrock, T | 1 |
| Desai, S; Gangadhar, BN; Jayakumar, PN; Keshavan, MS; Subbakrishna, D; Velayudhan, L; Venkatasubramanian, G | 1 |
| Goto, N; Hayashi, K; Hori, H; Ikenouchi-Sugita, A; Kakeda, S; Korogi, Y; Moriya, J; Nakamura, J; Ueda, N; Umene-Nakano, W; Yoshimura, R | 1 |
| Fannon, D; Kuipers, E; Kumari, V; Lythgoe, D; Parbhakar, VA; Premkumar, P; Williams, SC | 1 |
| Arida, RM; Cavalheiro, EA; Cysneiros, RM; Gattaz, WF; Schmitt, A; Scorza, FA | 1 |
| Ballmaier, M; Brühl, R; Gallinat, J; Häke, I; Klär, AA; Leopold, K; Schaefer, M; Schubert, F | 1 |
| Akella, NS; Avsar, KB; Bolding, MS; den Hollander, JA; Knowlton, RC; Lahti, AC; Reid, MA; Stoeckel, LE; White, DM | 1 |
| Cohen, BM; McCarthy, J; Ongür, D; Prescot, AP; Renshaw, PF | 1 |
| Bramon, E; McGuire, PK; Pauls, A; Stone, JM; Sumich, A | 1 |
| Reynolds, GP; Reynolds, LM | 1 |
| Apfeldorf, W; Bustillo, JR; Caprihan, A; Chen, H; Gasparovic, C; Lauriello, J; Mullins, P; Posse, S; Qualls, C | 1 |
| Brugger, S; Davis, JM; Leucht, S; Stone, JM | 1 |
| Akhadov, TA; Barkhatova, AN; Kaleda, VG; Kupriianov, DA; Lebedeva, IS; Mitrofanov, AA; Petriaĭkin, AV; Petriaĭkin, FA; Semenova, NA | 1 |
| Bohner, G; Forstreuter, F; Gallinat, J; Gudlowski, Y; Heinz, A; Juckel, G; Klingebiel, R; Mavrogiorgou, P; Norra, C; Ozgürdal, S; Scheel, M; Uhl, I; Witthaus, H | 1 |
| Calvin, S; Janish, A; Kanigere, M; Menon, J; Radhakrishnan, R; Srinivasan, K | 1 |
| Backens, M; Ekawardhani, S; Falkai, P; Gruber, O; Hasan, A; Meyer, J; Reith, W; Scherk, H; Schmitt, A; Schneider-Axmann, T; Wobrock, T | 1 |
| Aoyama, N; Densmore, M; Drost, DJ; Manchanda, R; Menon, RS; Neufeld, RW; Northcott, S; Pavlosky, WF; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, PC | 1 |
| Capizzano, AA; Ho, BC; Toscano, JL | 1 |
| Bibulowicz, D; Galinska, B; Konarzewska, B; Poplawska, R; Simonienko, K; Szulc, A; Tarasow, E; Walecki, J; Waszkiewicz, N | 1 |
| Antonius, D; Babb, JS; Gonen, O; Hardy, CJ; Malaspina, D; Messinger, JW; Perry, NN; Tal, A | 1 |
| Block, W; Fingerhut, N; Jessen, F; Kühn, KU; Maier, W; Petrovsky, N; Schild, HH; Sprinkart, AM; Träber, F; Wagner, M | 1 |
| Cuenod, M; das Neves Duarte, JM; Do, KQ; Gholam-Razaee, MM; Gruetter, R; Kulak, A | 1 |
| Chen, ZF; Collier, DA; Deng, W; He, ZL; Li, ML; Li, T; Ma, X | 1 |
| Agarwal, N; Port, JD | 1 |
| Cohen, BM; Cooper, A; Du, F; Öngür, D; Renshaw, PF | 1 |
| Huang, L; Jia, YB; Ling, XY; Wang, Y; Zhong, SM | 1 |
| den Hollander, J; Kraguljac, NV; Lahti, AC; Reid, MA; White, DM | 1 |
| Avsar, KB; Bolding, MS; den Hollander, JA; Hutcheson, NL; Knowlton, RC; Kraguljac, NV; Lahti, AC; Reid, MA; White, DM | 1 |
| Barch, DM; Buchanan, RW; Colibazzi, T; Csernansky, JG; Dong, Z; Girgis, RR; Goff, DC; Harms, MP; Jarskog, LF; Javitt, DC; Kangarlu, A; Keefe, RS; Kegeles, LS; Lieberman, JA; Marder, SR; McEvoy, JP; McMahon, RP; Peterson, BS | 1 |
| Ando, K; Isoda, H; Iyo, M; Matsumoto, H; Mori, N; Takei, N | 1 |
| Abe, O; Aoki, S; Fukuda, R; Fukui, T; Iwanami, A; Kasai, K; Kato, N; Kato, T; Kuroki, N; Ohtomo, K; Tsujii, K; Yamada, H; Yamasaki, S; Yamasue, H | 1 |
| Dezortová, M; Hájek, M; Hájek, T; Harantová, P; Spaniel, F; Tintera, J | 1 |
| Marx, J | 1 |
| Braus, DF; Ende, G; Henn, FA; Walter, S; Weber-Fahr, W | 1 |
| Nudmamud, S; Reynolds, GP; Reynolds, LM | 1 |
| Baeza, I; Bernardo, M; Giménez, M; Junqué, C; Mercader, JM; Pérez, M; Salamero, M; Vendrell, P | 1 |
| Doku, V; Fannon, D; O'Céallaigh, S; Sharma, T; Shew, C; Simmons, A; Sumich, A; Tennakoon, L | 1 |
| HOPKINS, GW; SIMON, W | 1 |
| Greenwood, K; Maier, M; Ron, MA; Sigmundsson, T; Simmons, A; Toone, BK; Williams, SC | 1 |
| Fukuda, R; Fukui, T; Iwanami, A; Kasai, K; Kato, N; Kato, T; Yamasue, H | 1 |
| Al-Semaan, Y; Densmore, M; Drost, DJ; Menon, RS; Neufeld, RW; Rajakumar, N; Schaefer, B; Théberge, J; Williamson, PC | 1 |
| Berger, G; Desmond, P; McGorry, PD; Pantelis, C; Phillips, LJ; Velakoulis, D; Wood, SJ; Yung, AR | 1 |
| Alger, JR; Asarnow, R; Caplan, R; Levitt, J; McCracken, JT; O'Neill, J; Toga, AW | 1 |
| Araújo, D; Crippa, JA; Hallak, JE; Sanches, RF; Zuardi, AW | 1 |
| Al-Semaan, Y; Bartha, R; Densmore, M; Drost, DJ; Malla, AK; Manchanda, R; Menon, R; Neufeld, RW; Schaefer, B; Théberge, J; Williamson, PC | 1 |
| Brazo, P; Constans, JM; Delamillieure, P; Dollfus, S; Fernandez, J | 1 |
| Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pfleiderer, B; Siegmund, A; Spitzberg, K; Suslow, T | 1 |
| Benito, C; Desco, M; Gispert, JD; Misiego, JM; Molina, V; Palomo, T; Pascau, J; Reig, S; Sánchez, J; Santamarta, C; Sanz, J; Sarramea, F | 1 |
| Braus, DF; Ende, G; Henn, FA; Hubrich, P; Kämmerer, N; Walter, S; Weber-Fahr, W | 1 |
| Deicken, RF; Feiwell, R; Jakary, A; Vinogradov, S | 1 |
| Hamer, RM; Lieberman, JA; Steen, RG | 1 |
| Tsai, SJ | 1 |
| Alathiaki, AS; Czernikiewicz, A; Dzienis, W; Galinska, B; Konarzewska, B; Kubas, B; Szulc, A; Tarasow, E; Walecki, J | 1 |
| Jakary, A; Théberge, J | 1 |
| Horiguchi, J; Inagaki, T; Kitagaki, H; Miyaoka, T; Mizuno, S; Oda, K; Yasukawa, R | 1 |
| Egan, MF; Goldberg, TE; Marenco, S; Sharrief, AZ; Steele, SU; Straub, RE; Weinberger, DR | 1 |
| Abbott, C; Bustillo, J | 1 |
| Keramat Ali, SM; Morshed, NM; Nahar, JS; Shams, M; Sobhan, MA | 1 |
| Asai, Y; Ikehira, H; Nishikawa, T; Obata, T; Okubo, Y; Sassa, T; Suhara, T; Tanaka, Y; Yoshitome, E | 1 |
| Başoğlu, C; Cetin, M; Ebrinç, S; Kandilcioğlu, H; Kizilkaya, E; Oner, O; Semiz, UB; Silit, E | 1 |
| Bertolino, A; Marenco, S; Weinberger, DR | 1 |
| Bhattacharya, P; Harris, K; Lin, A; Ross, B; Tran, T; Wong, W | 1 |
| Berning, J; Block, W; Falkai, P; Jessen, F; Maier, W; Scherk, H; Schild, HH; Tepest, R; Theyson, S; Träber, F; Wagner, M | 1 |
| Arolt, V; Heindel, W; Kersting, A; Ohrmann, P; Pedersen, A; Pfleiderer, B; Rothermundt, M; Siegmund, A; Spitzberg, K; Suslow, T | 1 |
| Jensen, JE; Rowland, LM; Théberge, J | 1 |
| Berger, GE; Conus, P; Desmond, P; Lambert, M; McGorry, PD; Pantelis, C; Stuart, GW; Velakoulis, D; Wood, SJ | 1 |
| Falkai, P; Maier, W | 1 |
| Benito, C; Luque, R; Molina, V; Palomo, T; Sanz, J; Sarramea, F | 1 |
| Kim, YK; Leonard, BE; Myint, AM; Park, SH; Scharpé, S; Steinbusch, HW; Verkerk, R | 1 |
| Bahn, S; Huffaker, SJ; Mimmack, ML; Ryan, M; Tkachev, D | 1 |
| Harte, MK; Reynolds, GP | 1 |
| Albalushi, T; Arinami, T; Horiuchi, Y; Inada, T; Ishiguro, H; Iwata, N; Koga, M; Muratake, T; Ozaki, N; Someya, T; Ujike, H | 1 |
| Keshavan, MS; MacMaster, FP; Montrose, DM; Nutche, J; Pettegrew, JW; Stanley, JA; Sweeney, JA; Vemulapalli, M | 1 |
| Czernikiewicz, A; Dzienis, W; Galińska, B; Kubas, B; Siergiejczyk, L; Szulc, A; Tarasów, E; Walecki, J | 1 |
| Czernikiewicz, A; Dzienis, W; Galińska, B; Konarzewska, B; Kubas, B; Poplawska, R; Szulc, A; Tarasów, E; Tomczak, AA; Walecki, J | 1 |
| Hong, CJ; Hou, SJ; Liao, DL; Liou, YJ; Tsai, SJ; Yen, FC | 1 |
| Benito, C; Desco, M; Leal, I; Molina, V; Palomo, T; Rebolledo, R; Reig, S; Sánchez, J; Sanz, J; Sarramea, F | 1 |
| Ertugrul, A; Uluğ, B | 1 |
| Brooks, WM; Bustillo, JR; Hammond, R; Hart, B; Jung, R; Lauriello, J; Qualls, C; Rowland, LM | 1 |
| Gross, KW; Hallas, BH; Horowitz, JM; Spernyak, JA; Torres, G | 1 |
| Berger, GE; McConchie, M; McGorry, PD; Pantelis, C; Proffitt, T; Velakoulis, D; Wellard, RM; Wood, SJ | 1 |
| Aydin, K; Guler, J; Ucok, A | 1 |
| Isaki, K; Ishii, Y; Itoh, S; Kimura, H; Koshino, Y; Murata, I; Murata, T; Nishio, M; Sakamoto, K | 1 |
| Collier, D; Gill, M; Hodgkinson, S; Pilowsky, L; Shaikh, S; Vallada, H; Van Os, J | 1 |
| Nasrallah, HA; Robitaille, PM; Schmalbrock, P; Skinner, TE | 1 |
| Beal, MF; Coyle, JT; Goff, DC; Tsai, G | 1 |
| Fujimoto, T; Fukuzako, H; Fukuzako, T; Hashiguchi, T; Hokazono, Y; Obo, Y; Takeuchi, K; Takigawa, M; Ueyama, K; Yamada, K | 1 |
| Akimoto, H; Fujimoto, T; Fukuzako, T; Nakano, T; Takano, T; Takeuchi, K; Yamada, K | 1 |
| Maier, M; Ron, MA | 1 |
| Fujii, K; Hamakawa, H; Inubushi, T; Kato, T; Murashita, J; Shioiri, T; Takahashi, S | 1 |
| Carr, TJ; Drost, DJ; Malla, A; Rylett, RJ; Stanley, JA; Thompson, RT; Williamson, PC | 1 |
| Barnett, AS; Bertolino, A; Duyn, JH; Frank, JA; Mattay, VS; Moonen, CT; Nawroz, S; Tedeschi, G; Weinberger, DR | 1 |
| Barron, YD; McMurray, CT; Mikesell, MJ; Nimgaonkar, VL; Sobell, JL; Sommer, SS | 1 |
| Corwin, F; Deicken, RF; Vinogradov, S; Weiner, MW; Zhou, L | 1 |
| Weinberger, DR | 1 |
| Griffin, WS; Husain, MM; Karson, CN; Komoroski, RA; Mrak, RE; Omori, M; Pearce, J | 1 |
| Aparicio-Legarza, MI; Cutts, AJ; Davis, B; Reynolds, GP | 1 |
| Campion, D; Lafargue, C; Laurent, C; Mallet, J; Martinez, M; Petit, M; Ravassard, P; Samolyk, D; Thibaut, F | 1 |
| Bigelow, LB; Herman, MM; Hyde, TM; Kleinman, JE; Noga, JT; Spurney, CF; Weinberger, DR | 1 |
| Bartha, R; Canaran, G; Carr, TJ; Cortese, L; Drost, DJ; Malla, A; Neufeld, RW; Rylett, RJ; Williamson, PC | 1 |
| Deicken, RF; Schuff, N; Weiner, MW; Zhou, L | 1 |
| Amico, ET; Evins, AE; Goff, DC; Shih, V | 1 |
| Deicken, RF; Fein, G; Schuff, N; Weiner, MW; Zhou, L | 1 |
| Adalsteinsson, E; Lim, KO; Pfefferbaum, A; Rosenbloom, MJ; Spielman, D; Sullivan, EV | 1 |
| Bertolino, A; Breier, A; Callicott, JH; Elman, I; Frank, JA; Mattay, VS; Tedeschi, G; Weinberger, DR | 1 |
| Crow, TJ; Deakin, JF; Gottfries, CG; Grenfeldt, B; Karlsson, I; Simpson, MD; Slater, P | 1 |
| Baer, L; Chang, RW; Coyle, JT; Flood, J; Goff, DC; Tsai, G | 1 |
| Barnett, IS; Bertolino, A; Callicott, JH; Duyn, JH; Frank, JA; Jacobsen, L; Kumra, S; Lestz, RM; Mattay, VS; Rapoport, JL; Weinberger, DR | 1 |
| Deakin, JF; Simpson, MD; Slater, P | 1 |
| Cardwell, D; Heimberg, C; Karson, CN; Komoroski, RA; Lawson, WB | 1 |
| Bertolino, A; Callicott, JH; Egan, MF; Frank, JA; Langheim, FJ; Mattay, VS; Weinberger, DR | 1 |
| Byne, W; Davis, KL | 1 |
| Bachevalier, J; Bertolino, A; Callicott, JH; Egan, M; Frank, JA; Knable, MB; Kolachana, B; Mattay, VS; Saunders, RC; Weinberger, DR | 1 |
| al-Semaan, YM; Bartha, R; Canaran, G; Carr, TJ; Densmore, M; Drost, DJ; Malla, AK; Neufeld, RW; Williamson, PC | 1 |
| Amend, D; Deicken, RF; Pegues, M | 1 |
| Innis, RB; Soares, JC | 1 |
| Lewis, DA | 1 |
| Berman, KF; Bertolino, A; Callicott, JH; Esposito, G; Frank, JA; Mattay, VS; Van Horn, JD; Weinberger, DR | 1 |
| Adler, C; Bertolino, A; Breier, A; Callicott, JH; Frank, JA; Mattay, VS; Pickar, D; Shapiro, M; Weinberger, DR | 1 |
| Fukuzako, H | 1 |
| Doi, W; Fukuzako, H; Fukuzako, T; Kodama, S; Sato, D; Takigawa, M; Yamada, K | 1 |
| Deicken, RF; Johnson, C; Pegues, M | 1 |
| Braus, DF; Ende, G; Henn, FA; Maudsley, AA; Soher, B; Walter, S; Weber-Fahr, W | 1 |
| Abadie, P; Benali, K; Brazo, P; Constans, JM; Courthéoux, P; Delamillieure, P; Dollfus, S; Fernandez, J; Petit, M; Thibaut, F; Vasse, T | 1 |
| Deicken, RF; Eliaz, Y; Johnson, C; Schuff, N | 1 |
| Ishimori, Y; Ito, H; Kado, H; Kimura, H; Koshimoto, Y; Murata, T; Omori, M; Wada, Y | 1 |
| Anjilvel, S; Chan, S; Ellis, SP; Gorman, JM; Kaufmann, CA; Kegeles, LS; Laruelle, M; Malaspina, D; Mann, JJ; Shungu, DC; Xanthopoulos, E | 1 |
| Maier, M; Mellers, J; Ron, MA; Toone, B; Trimble, M | 1 |
| Bayer, TA; Block, W; Falkai, P; Honer, WG; Maier, W; Müller, DJ; Rietschel, M; Schild, HH; Schulze, TG; Tepest, R; Träber, F | 1 |
| Bertolino, A; Callicott, JH; Egan, MF; Langheim, FJ; Mattay, VS; Weinberger, DR | 1 |
| Bertolino, A; Callicott, JH; Coppola, R; Duyn, J; Goldberg, TE; Langheim, FJ; Mattay, VS; Weinberger, DR | 1 |
| Allen, PS; Asghar, S; Hanstock, CC; Silverstone, P; Tibbo, P | 1 |
| Bertolino, A; Callicott, JH; Egan, MF; Mattay, VS; Rakow, R; Weidenhammer, KM; Weinberger, DR | 1 |
| Bustillo, JR; Lauriello, J; Rowland, L | 1 |
| Bastin, ME; Best, JJ; Cunningham-Owens, DG; Johnstone, EC; Lawrie, SM; Marshall, I; McConnell, S; Steel, RM | 1 |
| Braus, DF; Ende, G; Henn, FA; Walter, S | 1 |
| Auer, DP; Bronisch, T; Grabner, A; Heidenreich, JO; Wetter, TC; Wilke, M | 1 |
| Brooks, WM; Bustillo, JR; Hammond, R; Hart, B; Lauriello, J; Petropoulos, H; Rowland, LM | 1 |
| Braus, DF; Demirakca, T; Ende, G; Henn, FA; Tost, H; Weber-Fahr, W | 1 |
| Levitt, P; Lewis, DA; Middleton, FA; Mirnics, K; Pierri, JN | 1 |
| Bachert, P; Braus, DF; Büchel, C; Ende, G; Henn, FA; Soher, BJ; Weber-Fahr, W | 1 |
| Bárány, M; Davis, JM; Sharma, R; Venkatasubramanian, PN | 1 |
| Deakin, JF; Royston, MC; Simpson, MD; Slater, P | 1 |
| Baruah, S; Davidson, AT; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Carlsson, A; Carlsson, M | 1 |
| Swahn, CG | 1 |
| Cross, AJ; Deakin, JF; Gilchrist, AC; Reynolds, GP; Royston, MC; Simpson, MD; Skan, WJ; Slater, P | 1 |
| Abuchowski, A; Davis, FF; Hansen, S; Perry, TL; Wright, JM | 1 |
26 review(s) available for aspartic acid and Dementia Praecox
| Article | Year |
|---|---|
The Role of D-Serine and D-Aspartate in the Pathogenesis and Therapy of Treatment-Resistant Schizophrenia.
Topics: Aspartic Acid; D-Aspartic Acid; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenia, Treatment-Resistant; Serine | 2022 |
Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status.
Topics: Aspartic Acid; Brain Diseases; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy; Schizophrenia | 2023 |
Magnetic resonance spectroscopy studies in subjects with high risk for psychosis: A meta-analysis and review.
Topics: Aspartic Acid; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2020 |
Treatment effects on neurometabolite levels in schizophrenia: A systematic review and meta-analysis of proton magnetic resonance spectroscopy studies.
Topics: Aspartic Acid; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Thalamus | 2020 |
Proton Magnetic Resonance Spectroscopy of N-acetyl Aspartate in Chronic Schizophrenia, First Episode of Psychosis and High-Risk of Psychosis: A Systematic Review and Meta-Analysis.
Topics: Aspartic Acid; Choline; Humans; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2020 |
A role for endothelial NMDA receptors in the pathophysiology of schizophrenia.
Topics: Aspartic Acid; Brain; Glutamic Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2022 |
Neurometabolite levels in antipsychotic-naïve/free patients with schizophrenia: A systematic review and meta-analysis of
Topics: Aspartic Acid; Brain; Humans; Proton Magnetic Resonance Spectroscopy; Schizophrenia | 2018 |
Metabolomics in patients with psychosis: A systematic review.
Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan | 2018 |
Current Practice and New Developments in the Use of In Vivo Magnetic Resonance Spectroscopy for the Assessment of Key Metabolites Implicated in the Pathophysiology of Schizophrenia.
Topics: Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Humans; Magnetic Resonance Spectroscopy; Schizophrenia | 2018 |
T2 relaxation effects on apparent N-acetylaspartate concentration in proton magnetic resonance studies of schizophrenia.
Topics: Aspartic Acid; Brain; Humans; Magnetic Resonance Spectroscopy; Reproducibility of Results; Schizophrenia | 2013 |
Thalamic nuclear abnormalities as a contributory factor in sudden cardiac deaths among patients with schizophrenia.
Topics: Antipsychotic Agents; Aspartic Acid; Death, Sudden, Cardiac; Epilepsy; Glutamine; Humans; Prefrontal Cortex; Schizophrenia; Thalamic Nuclei | 2010 |
Proton magnetic resonance spectroscopy and illness stage in schizophrenia--a systematic review and meta-analysis.
Topics: Aspartic Acid; Data Interpretation, Statistical; Disease Progression; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Publication Bias; Regression Analysis; Risk; Schizophrenia; Schizophrenic Psychology; Temporal Lobe; Thalamus | 2011 |
MR spectroscopy in schizophrenia.
Topics: Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Magnetic Resonance Spectroscopy; Neurotransmitter Agents; Schizophrenia | 2011 |
Proton magnetic resonance spectroscopy of the frontal lobe in schizophrenics: a critical review of the methodology.
Topics: Aspartic Acid; Brain Chemistry; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia | 2004 |
N-acetyl-aspartate levels in the dorsolateral prefrontal cortex in the early years of schizophrenia are inversely related to disease duration.
Topics: Adult; Age Factors; Antipsychotic Agents; Aspartic Acid; Choline; Chronic Disease; Creatine; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Risperidone; Schizophrenia; Time Factors | 2005 |
Measurement of brain metabolites by 1H magnetic resonance spectroscopy in patients with schizophrenia: a systematic review and meta-analysis.
Topics: Aspartic Acid; Brain Chemistry; Humans; Magnetic Resonance Spectroscopy; Schizophrenia; Tritium | 2005 |
Central N-acetyl aspartylglutamate deficit: a possible pathogenesis of schizophrenia.
Topics: Animals; Aspartic Acid; Brain; Dipeptides; Glutamic Acid; Humans; Models, Neurological; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2005 |
What have we learned from proton magnetic resonance spectroscopy about schizophrenia? A critical update.
Topics: Aspartic Acid; Biomarkers; Brain; Choline; Creatine; Cross-Over Studies; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; N-Methylaspartate; Neurons; Protons; Schizophrenia; Temporal Lobe | 2006 |
In vivo NMR measures of NAA and the neurobiology of schizophrenia.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Brain-Derived Neurotrophic Factor; Cerebrovascular Circulation; Humans; Magnetic Resonance Spectroscopy; Regional Blood Flow; Schizophrenia; Statistics as Topic | 2006 |
[Advances in neurobiological understanding of schizophrenia. Perspectives for new therapeutic concepts].
Topics: Animals; Aspartic Acid; Brain; Carrier Proteins; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Neuregulin-1; Neurons; Neuropil; Risk Factors; Schizophrenia; Synaptic Transmission | 2006 |
The biological basis of schizophrenia: new directions.
Topics: Animals; Aspartic Acid; Brain; Cholecystokinin; Disease Models, Animal; Dopamine; Entorhinal Cortex; gamma-Aminobutyric Acid; Genetic Linkage; Genetic Markers; Glutamic Acid; Humans; RNA, Messenger; Rodentia; Schizophrenia | 1997 |
Neurochemical brain imaging investigations of schizophrenia.
Topics: Aspartic Acid; Brain; Corpus Striatum; Dopamine; Glutamic Acid; Homovanillic Acid; Humans; Magnetic Resonance Imaging; Receptors, Dopamine D2; Receptors, GABA; Schizophrenia; Serotonin; Synaptic Transmission; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1999 |
Specific relationship between prefrontal neuronal N-acetylaspartate and activation of the working memory cortical network in schizophrenia.
Topics: Adult; Aspartic Acid; Brain; Female; Humans; Magnetic Resonance Spectroscopy; Male; Memory; Models, Neurological; Neural Pathways; Neuropsychological Tests; Oxygen Radioisotopes; Prefrontal Cortex; Regional Blood Flow; Schizophrenia; Tomography, Emission-Computed; Water | 2000 |
Proton magnetic resonance spectroscopy of the human brain in schizophrenia.
Topics: Aspartic Acid; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Protons; Schizophrenia | 2000 |
Proton magnetic resonance spectroscopy (H-MRS) studies of schizophrenia.
Topics: Aspartic Acid; Brain Chemistry; Chronic Disease; Frontal Lobe; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe | 2001 |
Interactions between glutamatergic and monoaminergic systems within the basal ganglia--implications for schizophrenia and Parkinson's disease.
Topics: Animals; Anticonvulsants; Aspartic Acid; Basal Ganglia; Biogenic Amines; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Humans; N-Methylaspartate; Parkinson Disease; Schizophrenia | 1990 |
15 trial(s) available for aspartic acid and Dementia Praecox
| Article | Year |
|---|---|
N-Acetyl-Aspartate in the dorsolateral prefrontal cortex in men with schizophrenia and auditory verbal hallucinations: A 1.5 T Magnetic Resonance Spectroscopy Study.
Topics: Adult; Aspartic Acid; Hallucinations; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Speech Perception; Temporal Lobe | 2018 |
Supplementation of antipsychotic treatment with sarcosine – GlyT1 inhibitor – causes changes of glutamatergic (1)NMR spectroscopy parameters in the left hippocampus in patients with stable schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Double-Blind Method; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine Plasma Membrane Transport Proteins; Hippocampus; Humans; Inositol; Male; Middle Aged; Sarcosine; Schizophrenia; Young Adult | 2015 |
In vivo occipital-frontal temperature-gradient in schizophrenia patients and its possible association with psychopathology: a magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Temperature; Water | 2008 |
Hippocampal plasticity in response to exercise in schizophrenia.
Topics: Adult; Aspartic Acid; Chronic Disease; Cognition Disorders; Exercise; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuronal Plasticity; Neuropsychological Tests; Schizophrenia | 2010 |
High energy phosphate abnormalities normalize after antipsychotic treatment in schizophrenia: a longitudinal 31P MRS study of basal ganglia.
Topics: Adenosine Triphosphate; Adult; Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Basal Ganglia; Female; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorus Isotopes; Psychiatric Status Rating Scales; Radionuclide Imaging; Schizophrenia; Young Adult | 2010 |
Proton magnetic resonance spectroscopy study of brain metabolite changes after antipsychotic treatment.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain; Brain Chemistry; Diagnostic and Statistical Manual of Mental Disorders; Female; Follow-Up Studies; Fourier Analysis; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Psychiatric Status Rating Scales; Schizophrenia; Thalamus; Young Adult | 2011 |
Effects of davunetide on N-acetylaspartate and choline in dorsolateral prefrontal cortex in patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Choline; Cognition; Creatine; Female; Functional Neuroimaging; Humans; Male; Middle Aged; Oligopeptides; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology | 2013 |
The effect of risperidone on metabolite measures in the frontal lobe, temporal lobe, and thalamus in schizophrenic patients. A proton magnetic resonance spectroscopy (1H MRS).
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Energy Metabolism; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Statistics as Topic; Temporal Lobe; Thalamus | 2005 |
[Comparison of right thalamus and temporal cortex metabolite levels of drug-naive first-episode psychotic and chronic schizophrenia in patients].
Topics: Aspartic Acid; Case-Control Studies; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Severity of Illness Index; Temporal Lobe; Thalamus | 2006 |
Proton magnetic resonance spectroscopy during initial treatment with antipsychotic medication in schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Brain; Brain Chemistry; Brain Mapping; Choline; Cognition; Dibenzothiazepines; Double-Blind Method; Female; Haloperidol; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Quetiapine Fumarate; Schizophrenia; Time | 2008 |
Hippocampal neuronal dysfunction in schizophrenia as measured by proton magnetic resonance spectroscopy.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Pilot Projects; Schizophrenia | 1998 |
Regionally specific neuronal pathology in untreated patients with schizophrenia: a proton magnetic resonance spectroscopic imaging study.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Neurons; Prefrontal Cortex; Schizophrenia | 1998 |
Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype.
Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Family; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Phenotype; Phosphocreatine; Prefrontal Cortex; Risk; Schizophrenia | 1998 |
The effect of treatment with antipsychotic drugs on brain N-acetylaspartate measures in patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain; Brain Chemistry; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Schizophrenia | 2001 |
A fully automated method for tissue segmentation and CSF-correction of proton MRSI metabolites corroborates abnormal hippocampal NAA in schizophrenia.
Topics: Adult; Algorithms; Aspartic Acid; Choline; Creatine; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Phosphocreatine; Schizophrenia | 2002 |
185 other study(ies) available for aspartic acid and Dementia Praecox
| Article | Year |
|---|---|
Abnormal neurobiochemical metabolites in the first
Topics: Aspartic Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Schizophrenia | 2021 |
Magnetic resonance spectroscopic evidence of increased choline in the dorsolateral prefrontal and visual cortices in recent onset schizophrenia.
Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Humans; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Schizophrenia; Visual Cortex | 2022 |
The glutamate/N-methyl-d-aspartate receptor (NMDAR) model of schizophrenia at 35: On the path from syndrome to disease.
Topics: Aspartic Acid; Glutamic Acid; Humans; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2022 |
Metabolite differences in the medial prefrontal cortex in schizophrenia patients with and without persistent auditory verbal hallucinations: a
Topics: Aspartic Acid; Hallucinations; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia | 2022 |
Interactions between dopamine transporter and N-methyl-d-aspartate receptor-related amino acids on cognitive impairments in schizophrenia.
Topics: Amino Acids; Arginine; Aspartic Acid; Cognitive Dysfunction; Corpus Striatum; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamates; Humans; Methionine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Tropanes | 2022 |
Correlation between abnormal N-acetyl-aspartate levels in posterior cingulate cortex and persistent auditory verbal hallucinations in Chinese patients with chronic schizophrenia.
Topics: Aspartic Acid; East Asian People; Gyrus Cinguli; Hallucinations; Humans; Magnetic Resonance Imaging; Schizophrenia | 2023 |
The impact of endurance training and table soccer on brain metabolites in schizophrenia.
Topics: Adult; Aspartic Acid; Brain; Cognition; Creatine; Endurance Training; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Inpatients; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Schizophrenia; Thalamus | 2020 |
Glutamatergic hypo-function in the left superior and middle temporal gyri in early schizophrenia: a data-driven three-dimensional proton spectroscopic imaging study.
Topics: Aspartic Acid; Creatine; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy; Protons; Schizophrenia | 2020 |
Metabolomics approach revealed robust changes in amino acid and biogenic amine signatures in patients with schizophrenia in the early course of the disease.
Topics: Adult; Amino Acids; Antipsychotic Agents; Asparagine; Aspartic Acid; Biogenic Amines; Chromatography, Liquid; Early Diagnosis; Female; Glutamic Acid; Glutamine; Humans; Male; Metabolome; Metabolomics; Proline; Schizophrenia; Tandem Mass Spectrometry; Taurine; Young Adult | 2020 |
The Relationship between the Level of Anterior Cingulate Cortex Metabolites, Brain-Periphery Redox Imbalance, and the Clinical State of Patients with Schizophrenia and Personality Disorders.
Topics: Adult; Antioxidants; Aspartic Acid; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Malondialdehyde; Oxidants; Oxidation-Reduction; Oxidative Stress; Personality Disorders; Prognosis; Psychotic Disorders; Schizophrenia; Young Adult | 2020 |
Preliminary Findings Associate Hippocampal
Topics: Adult; Aspartic Acid; Choline; Female; Hippocampus; Humans; Male; Mania; Middle Aged; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2021 |
Identification of the gene that codes for the σ
Topics: Alzheimer Disease; Animals; Aspartic Acid; Carrier Proteins; Cattle; Cholesterol; Endoplasmic Reticulum; Gene Expression Regulation; Humans; Insecta; Intracellular Signaling Peptides and Proteins; Ligands; Liver; MCF-7 Cells; Membrane Glycoproteins; Membrane Proteins; Niemann-Pick C1 Protein; PC12 Cells; Protein Binding; Rats; Receptors, sigma; Recombinant Proteins; RNA, Small Interfering; Schizophrenia | 2017 |
7T Proton Magnetic Resonance Spectroscopy of the Anterior Cingulate Cortex in First-Episode Schizophrenia.
Topics: Adult; Aspartic Acid; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult | 2019 |
Striatal neurometabolite levels in patients with schizophrenia undergoing long-term antipsychotic treatment: A proton magnetic resonance spectroscopy and reliability study.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Choline; Corpus Striatum; Creatine; Female; Glutamic Acid; Glutamine; Humans; Inositol; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Reproducibility of Results; Schizophrenia | 2018 |
Glutathione and glutamate in schizophrenia: a 7T MRS study.
Topics: Adult; Aspartic Acid; Brain; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Proton Magnetic Resonance Spectroscopy; Schizophrenia | 2020 |
Neurometabolic abnormalities in the associative striatum in antipsychotic-naïve first episode psychosis patients.
Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Case-Control Studies; Choline; Corpus Striatum; Disease Progression; Dopamine; Female; Glutamic Acid; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia; Young Adult | 2018 |
Proton magnetic resonance spectroscopic imaging of gray and white matter in bipolar-I and schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Female; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult | 2019 |
Role of glia in prefrontal white matter abnormalities in first episode psychosis or mania detected by diffusion tensor spectroscopy.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Myelin Sheath; Neuroglia; Neurons; Prefrontal Cortex; Psychotic Disorders; Schizophrenia; White Matter; Young Adult | 2019 |
Proton magnetic resonance spectroscopy of the substantia nigra in schizophrenia.
Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Protons; Schizophrenia; Substantia Nigra; Young Adult | 2013 |
Brain metabolite alterations in young adults at familial high risk for schizophrenia using proton magnetic resonance spectroscopy.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Brain; Cognition Disorders; Family Health; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Young Adult | 2013 |
Decreased levels of D-aspartate and NMDA in the prefrontal cortex and striatum of patients with schizophrenia.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Chromatography, High Pressure Liquid; Corpus Striatum; Female; Humans; Male; Middle Aged; N-Methylaspartate; Postmortem Changes; Prefrontal Cortex; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2013 |
Proton magnetic resonance spectroscopy (H-MRS) in chronic schizophrenia. A single-voxel study in three regions involved in a pathogenetic theory.
Topics: Adult; Analysis of Variance; Aspartic Acid; Cerebellum; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Psychiatric Status Rating Scales; Schizophrenia; Thalamus | 2013 |
Antipsychotic treatment resistance in schizophrenia associated with elevated glutamate levels but normal dopamine function.
Topics: Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Dihydroxyphenylalanine; Dopamine; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Positron-Emission Tomography; Protons; Schizophrenia | 2014 |
Reduced frontal glutamate + glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical high risk for psychosis or with first-episode schizophrenia.
Topics: Adolescent; Adult; Aspartic Acid; Chronic Disease; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prodromal Symptoms; Psychotic Disorders; Risk; Schizophrenia; Young Adult | 2014 |
Effects of cannabis and familial loading on subcortical brain volumes in first-episode schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain; Brain Chemistry; Caudate Nucleus; Choline; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Marijuana Abuse; Psychiatric Status Rating Scales; Putamen; Schizophrenia; Schizophrenic Psychology; Sex Characteristics; Socioeconomic Factors | 2013 |
Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia.
Topics: Adult; Aspartic Acid; Biomarkers; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multimodal Imaging; Schizophrenia; Young Adult | 2013 |
Magnetic resonance spectroscopy investigations of functionally defined language areas in schizophrenia patients with and without auditory hallucinations.
Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Broca Area; Female; Hallucinations; Humans; Language; Magnetic Resonance Imaging; Male; Middle Aged; Molecular Imaging; Nerve Net; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Wernicke Area | 2014 |
Atypical antipsychotic drug treatment for 6 months restores N-acetylaspartate in left prefrontal cortex and left thalamus of first-episode patients with early onset schizophrenia: A magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Schizophrenia; Thalamus; Treatment Outcome; Young Adult | 2014 |
Prefrontal glutamate levels differentiate early phase schizophrenia and methamphetamine addiction: a (1)H MRS study at 3Tesla.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Glutamic Acid; Humans; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Young Adult | 2014 |
Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia.
Topics: Adolescent; Adult; Animals; Aspartic Acid; Dentate Gyrus; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Middle Aged; Nerve Tissue Proteins; Postmortem Changes; Protons; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction; Young Adult | 2015 |
Study of the inferior colliculus in patients with schizophrenia by magnetic resonance spectroscopy.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chlorpromazine; Choline; Creatine; Female; Hallucinations; Humans; Inferior Colliculi; Male; Middle Aged; Nuclear Magnetic Resonance, Biomolecular; Schizophrenia | 2014 |
GABA and glutamate in schizophrenia: a 7 T ¹H-MRS study.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Intelligence; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Young Adult | 2014 |
Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: a proton magnetic resonance spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Auditory Cortex; Bipolar Disorder; Creatine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe; Young Adult | 2015 |
Decoupling of N-acetyl-aspartate and glutamate within the dorsolateral prefrontal cortex in schizophrenia.
Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Neuropsychological Tests; Oxidative Stress; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia | 2015 |
N-acetylaspartate reduction in the medial prefrontal cortex following 8 weeks of risperidone treatment in first-episode drug-naïve schizophrenia patients.
Topics: Adult; Age of Onset; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Female; Follow-Up Studies; Humans; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Risperidone; Schizophrenia; Young Adult | 2015 |
Diffusion in the corpus callosum in patients with early schizophrenia.
Topics: Adolescent; Adult; Aspartic Acid; Corpus Callosum; Diffusion Magnetic Resonance Imaging; Female; Humans; Male; Schizophrenia; Young Adult | 2015 |
The Paradoxical Relationship between White Matter, Psychopathology and Cognition in Schizophrenia: A Diffusion Tensor and Proton Spectroscopic Imaging Study.
Topics: Adult; Aged; Aspartic Acid; Cognition Disorders; Diffusion Tensor Imaging; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Neuropsychological Tests; Protons; Psychiatric Status Rating Scales; Psychopathology; Schizophrenia; Schizophrenic Psychology; Spectroscopy, Near-Infrared; Statistics as Topic; White Matter; Young Adult | 2015 |
Hypo-metabolism of the rostral anterior cingulate cortex associated with working memory impairment in 18 cases of schizophrenia.
Topics: Adult; Aging; Aspartic Acid; Creatine; Female; Gliosis; Gyrus Cinguli; Humans; Inositol; Intelligence Tests; Male; Memory Disorders; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Retrospective Studies; Schizophrenia; Schizophrenic Psychology; Sex Characteristics; Young Adult | 2016 |
Alterations in frontal white matter neurochemistry and microstructure in schizophrenia: implications for neuroinflammation.
Topics: Adult; Age Factors; Anisotropy; Aspartic Acid; Case-Control Studies; Choline; Creatine; Diffusion Tensor Imaging; Female; Frontal Lobe; Glutamic Acid; Humans; Inflammation; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Schizophrenia; White Matter; Young Adult | 2015 |
Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia.
Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Female; Frontal Lobe; Glutamic Acid; Gray Matter; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Prodromal Symptoms; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Risk; Schizophrenia; Young Adult | 2015 |
The predictive value of baseline NAA/Cr for treatment response of first-episode schizophrenia: A ¹H MRS study.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain; Case-Control Studies; Creatine; Female; Hallucinations; Humans; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Young Adult | 2015 |
Glutamatergic dysfunction linked to energy and membrane lipid metabolism in frontal and anterior cingulate cortices of never treated first-episode schizophrenia patients.
Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Membrane Lipids; Phospholipids; Phosphorus Isotopes; Protons; Psychiatric Status Rating Scales; Schizophrenia; Young Adult | 2015 |
Elevated Myo-Inositol, Choline, and Glutamate Levels in the Associative Striatum of Antipsychotic-Naive Patients With First-Episode Psychosis: A Proton Magnetic Resonance Spectroscopy Study With Implications for Glial Dysfunction.
Topics: Adult; Aspartic Acid; Choline; Corpus Striatum; Glutamic Acid; Glutamine; Humans; Inositol; Neuroglia; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2016 |
A combined diffusion tensor imaging and magnetic resonance spectroscopy study of patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Creatine; Diffusion Tensor Imaging; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Multimodal Imaging; Myelin Sheath; Psychotic Disorders; Schizophrenia; White Matter | 2016 |
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glutathione; Gyrus Cinguli; Humans; Inositol; Male; Proton Magnetic Resonance Spectroscopy; Psychotic Disorders; Schizophrenia | 2016 |
Prefrontal neuronal integrity predicts symptoms and cognition in schizophrenia and is sensitive to genetic heterogeneity.
Topics: Adult; Aspartic Acid; Cognition; Female; Humans; Intelligence Tests; Magnetic Resonance Imaging; Male; Membrane Proteins; Mutation, Missense; Nerve Tissue Proteins; Polymorphism, Genetic; Prefrontal Cortex; Psychiatric Status Rating Scales; Psychotic Disorders; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Schizophrenia; Schizophrenic Psychology | 2016 |
Metabolic Abnormalities in the Hippocampus of Patients with Schizophrenia: A 3D Multivoxel MR Spectroscopic Imaging Study at 3T.
Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Hippocampus; Humans; Imaging, Three-Dimensional; Male; Middle Aged; Neuroimaging; Proton Magnetic Resonance Spectroscopy; Schizophrenia | 2016 |
Glutamatergic and Neuronal Dysfunction in Gray and White Matter: A Spectroscopic Imaging Study in a Large Schizophrenia Sample.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Choline; Creatine; Female; Glutamic Acid; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult | 2017 |
Neuroprotective Effect of Modified Electroconvulsive Therapy for Schizophrenia: A Proton Magnetic Resonance Spectroscopy Study.
Topics: Adult; Aspartic Acid; Creatine; Electroconvulsive Therapy; Female; Humans; Male; Neuroprotection; Outcome Assessment, Health Care; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Thalamus; Young Adult | 2017 |
Automatic relevance determination for identifying thalamic regions implicated in schizophrenia.
Topics: Aspartic Acid; Brain Mapping; Choline; Humans; Image Processing, Computer-Assisted; Linear Models; Magnetic Resonance Spectroscopy; Male; Nerve Net; Protons; Schizophrenia; Thalamus | 2008 |
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania.
Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Neuroglia; Neurons; Neurotransmitter Agents; Occipital Lobe; Parietal Lobe; Pilot Projects; Reference Values; Schizophrenia; Synaptic Transmission; Young Adult | 2008 |
Proton MRS in twin pairs discordant for schizophrenia.
Topics: Aspartic Acid; Creatine; Female; Glutamic Acid; Glycerylphosphorylcholine; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Phosphocreatine; Phosphorylcholine; Prefrontal Cortex; Protons; Schizophrenia; Twins, Dizygotic; Twins, Monozygotic | 2010 |
Spectroscopic metabolomic abnormalities in the thalamus related to auditory hallucinations in patients with schizophrenia.
Topics: Adult; Aspartic Acid; Brief Psychiatric Rating Scale; Choline; Creatine; Diagnostic and Statistical Manual of Mental Disorders; Functional Laterality; Hallucinations; Humans; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Thalamus | 2008 |
SNAP-25 genotype influences NAA/Cho in left hippocampus.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; DNA; Female; Genotype; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Obsessive-Compulsive Disorder; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Synaptosomal-Associated Protein 25 | 2008 |
Learning potential on the WCST in schizophrenia is related to the neuronal integrity of the anterior cingulate cortex as measured by proton magnetic resonance spectroscopy.
Topics: Adult; Aptitude; Aspartic Acid; Brain; Cognition Disorders; Female; Functional Laterality; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Neuropsychological Tests; Prefrontal Cortex; Radionuclide Imaging; Schizophrenia; Schizophrenic Psychology | 2008 |
Metabolite changes and gender differences in schizophrenia using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS).
Topics: Adult; Analysis of Variance; Aspartic Acid; Basal Ganglia; Choline; Creatine; Female; Glutamic Acid; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Schizophrenia; Sex Characteristics; Young Adult | 2009 |
Proton magnetic resonance spectroscopy of the frontal, cingulate and perirolandic cortices and its relationship to skin conductance in patients with schizophrenia.
Topics: Acoustic Stimulation; Adult; Aspartic Acid; Case-Control Studies; Cerebral Cortex; Choline; Creatine; Female; Galvanic Skin Response; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Socioeconomic Factors | 2008 |
Proton magnetic resonance spectroscopy in subjects with high genetic risk of schizophrenia: investigation of anterior cingulate, dorsolateral prefrontal cortex and thalamus.
Topics: Adolescent; Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Psychiatric Status Rating Scales; Schizophrenia; Thalamus; Young Adult | 2009 |
[Proton magnetic resonance spectroscopic imaging of the hippocampus in schizophrenia patients before and after surgery].
Topics: Adolescent; Adult; Aspartic Acid; Case-Control Studies; Choline; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Stereotaxic Techniques; Young Adult | 2009 |
MR spectroscopic evaluation of N-acetylaspartate's T2 relaxation time and concentration corroborates white matter abnormalities in schizophrenia.
Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Dipeptides; Female; Frontal Lobe; Glutamic Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Phosphocreatine; Protons; Schizophrenia; Water | 2009 |
Striatal metabolic alterations in non-psychotic adolescent offspring at risk for schizophrenia: a (1)H spectroscopy study.
Topics: Adolescent; Aspartic Acid; Chi-Square Distribution; Child; Cohort Studies; Corpus Striatum; Creatine; Energy Metabolism; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Psychiatric Status Rating Scales; Schizophrenia; Sex Factors; Siblings; Young Adult | 2009 |
Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Behavior, Animal; Binding Sites; Carrier Proteins; D-Amino-Acid Oxidase; Female; Glycine; Male; Mice; Mutation; Nerve Tissue Proteins; Nervous System; Phenotype; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Stereoisomerism | 2010 |
1H-MRS at 4 tesla in minimally treated early schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Female; Frontal Lobe; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Protons; Schizophrenia; Thalamus; Time Factors | 2010 |
T2 relaxation time abnormalities in bipolar disorder and schizophrenia.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Tissue Distribution | 2010 |
Schizophrenia-related endophenotypes in heterozygous neuregulin-1 'knockout' mice.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuregulin-1; Phencyclidine; Phenotype; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Sex Factors; Social Behavior | 2010 |
Comparison of brain N-acetylaspartate levels and serum brain-derived neurotrophic factor (BDNF) levels between patients with first-episode schizophrenia psychosis and healthy controls.
Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Brain Chemistry; Brain-Derived Neurotrophic Factor; Case-Control Studies; Female; Homovanillic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Methoxyhydroxyphenylglycol; Middle Aged; Occipital Lobe; Parietal Lobe; Schizophrenia; Young Adult | 2011 |
N-acetyl aspartate concentration in the anterior cingulate cortex in patients with schizophrenia: a study of clinical and neuropsychological correlates and preliminary exploration of cognitive behaviour therapy effects.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Child; Choline; Cognition Disorders; Cognitive Behavioral Therapy; Creatine; Cross-Sectional Studies; Female; Follow-Up Studies; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Regression Analysis; Schizophrenia; Young Adult | 2010 |
Interaction of hippocampal volume and N-acetylaspartate concentration deficits in schizophrenia: a combined MRI and 1H-MRS study.
Topics: Adult; Aspartic Acid; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Organ Size; Protons; Schizophrenia; Tissue Distribution | 2010 |
Assessments of function and biochemistry of the anterior cingulate cortex in schizophrenia.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain Chemistry; Brain Mapping; Creatine; Female; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Protons; Psychiatric Status Rating Scales; Radionuclide Imaging; Reaction Time; Schizophrenia; Young Adult | 2010 |
Elevated gamma-aminobutyric acid levels in chronic schizophrenia.
Topics: Adult; Analysis of Variance; Aspartic Acid; Case-Control Studies; Chronic Disease; Creatine; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Radionuclide Imaging; Schizophrenia | 2010 |
Thalamic neurochemical abnormalities in individuals with prodromal symptoms of schizophrenia - relationship to auditory event-related potentials.
Topics: Acoustic Stimulation; Adult; Aspartic Acid; Electroencephalography; Evoked Potentials, Auditory; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Neurochemistry; Protons; Radionuclide Imaging; Schizophrenia; Thalamus; Young Adult | 2010 |
Differential regional N-acetylaspartate deficits in postmortem brain in schizophrenia, bipolar disorder and major depressive disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Depressive Disorder, Major; Dipeptides; Female; Humans; Male; Middle Aged; Schizophrenia | 2011 |
Glutamate as a marker of cognitive function in schizophrenia: a proton spectroscopic imaging study at 4 Tesla.
Topics: Adult; Age Factors; Aspartic Acid; Biomarkers; Brain; Cognition Disorders; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuropsychological Tests; Protons; Schizophrenia; Schizophrenic Psychology | 2011 |
[Hemodynamic and biochemical characteristics of the prefrontal cortex after the first episode of juvenile schizophrenia].
Topics: Aspartic Acid; Biomarkers; Creatine; Female; Hemodynamics; Humans; Magnetic Resonance Imaging; Male; Phosphocreatine; Prefrontal Cortex; Schizophrenia; Young Adult | 2010 |
1 H-MR spectroscopy in ultra-high risk and first episode stages of schizophrenia.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Mapping; Chi-Square Distribution; Choline; Creatine; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Young Adult | 2011 |
Association between unconjugated bilirubin and schizophrenia.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bilirubin; Case-Control Studies; Female; Humans; Hyperbilirubinemia; Male; Middle Aged; Regression Analysis; Retrospective Studies; Schizophrenia; Young Adult | 2011 |
Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Creatine; Female; Genetic Association Studies; Genotype; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Methionine; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Protons; Schizophrenia; Valine; Verbal Learning | 2012 |
Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia.
Topics: Activities of Daily Living; Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Brain Mapping; Case-Control Studies; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Participation; Thalamus; Time Factors | 2011 |
Magnetic resonance spectroscopy of limbic structures displays metabolite differences in young unaffected relatives of schizophrenia probands.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Brain Mapping; Choline; Family; Female; Humans; Image Processing, Computer-Assisted; Limbic System; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Tritium; Young Adult | 2011 |
Multivoxel proton MR spectroscopy used to distinguish anterior cingulate metabolic abnormalities in patients with schizophrenia.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Creatine; Female; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Spectroscopy; Male; Protons; Schizophrenia; Sensitivity and Specificity | 2011 |
N-acetylaspartylglutamate (NAAG) and N-acetylaspartate (NAA) in patients with schizophrenia.
Topics: Adult; Aspartic Acid; Dipeptides; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex; Protons; Psychiatric Status Rating Scales; Schizophrenia | 2013 |
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia | 2012 |
Detection of metabolites in the white matter of frontal lobes and hippocampus with proton in first-episode treatment-naïve schizophrenia patients.
Topics: Adult; Aspartic Acid; Biomarkers; Case-Control Studies; Choline; Creatine; Dominance, Cerebral; Female; Frontal Lobe; Hippocampus; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Protons; Schizophrenia; Severity of Illness Index | 2012 |
Water and metabolite transverse T2 relaxation time abnormalities in the white matter in schizophrenia.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Mapping; Diffusion Magnetic Resonance Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Myelinated; Psychiatric Status Rating Scales; Relaxation; Schizophrenia; Sex Factors; Water; Young Adult | 2012 |
[Proton magnetic resonance spectroscopy and diffusion tensor imaging study of first-episode patients with positive symptoms of schizophrenia].
Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Diffusion Tensor Imaging; Female; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Young Adult | 2012 |
Regional decoupling of N-acetyl-aspartate and glutamate in schizophrenia.
Topics: Adult; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Female; Glutamic Acid; Hippocampus; Homeostasis; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 2012 |
Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging.
Topics: Adult; Analysis of Variance; Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oxygen; Protons; Schizophrenia; Young Adult | 2012 |
Neural damage in the lenticular nucleus linked with tardive dyskinesia in schizophrenia: a preliminary study using proton magnetic resonance spectroscopy.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Choline; Corpus Striatum; Creatine; Dyskinesia, Drug-Induced; Female; Humans; Linear Models; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Statistics, Nonparametric | 2002 |
1H-MR spectroscopy and gray matter volume of the anterior cingulate cortex in schizophrenia.
Topics: Adult; Aspartic Acid; Choline; Creatine; Emotions; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology | 2002 |
Differences in fMRI and MRS in a monozygotic twin pair discordant for schizophrenia (case report).
Topics: Adult; Aspartic Acid; Cerebral Cortex; Creatine; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Speech; Twins, Monozygotic | 2003 |
Neuroscience. Minor variation in growth-factor gene impairs human memory.
Topics: Amino Acid Substitution; Aspartic Acid; Brain Mapping; Brain-Derived Neurotrophic Factor; Genetic Variation; Hippocampus; Humans; Long-Term Potentiation; Magnetic Resonance Imaging; Memory; Nerve Endings; Neurons; Protein Transport; Schizophrenia | 2003 |
Multiregional 1H-MRSI of the hippocampus, thalamus, and basal ganglia in schizophrenia.
Topics: Adult; Aspartic Acid; Basal Ganglia; Case-Control Studies; Choline; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Putamen; Schizophrenia; Thalamus | 2003 |
N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: a postmortem study.
Topics: Aspartic Acid; Autopsy; Biomarkers; Bipolar Disorder; Case-Control Studies; Chromatography, High Pressure Liquid; Depressive Disorder; Dipeptides; Frontal Lobe; Humans; Schizophrenia; Temporal Lobe | 2003 |
Basal ganglia N-acetylaspartate correlates with the performance in the procedural task 'Tower of Hanoi' of neuroleptic-naive schizophrenic patients.
Topics: Adult; Aspartic Acid; Basal Ganglia; Humans; Learning; Learning Disabilities; Magnetic Resonance Spectroscopy; Male; Problem Solving; Schizophrenia; Schizophrenic Psychology | 2003 |
Selective deficit of hippocampal N-acetylaspartate in antipsychotic-naive patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Basal Ganglia; Case-Control Studies; Creatine; Female; Hippocampus; Humans; Male; Phosphocreatine; Prefrontal Cortex; Schizophrenia | 2003 |
Treatment of schizophrenia with potassium and magnesium aspartates (spartase).
Topics: Aspartic Acid; Humans; Magnesium; Potassium; Schizophrenia | 1963 |
Frontal lobe N-acetylaspartate correlates with psychopathology in schizophrenia: a proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Prefrontal Cortex; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Schizophrenic Psychology | 2003 |
Drug-induced parkinsonism in relation to choline-containing compounds measured by 1H-MR spectroscopy in putamen of chronically medicated patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Basal Ganglia Diseases; Choline; Chronic Disease; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurologic Examination; Parkinson Disease, Secondary; Phosphocreatine; Putamen; Reference Values; Schizophrenia; Schizophrenic Psychology | 2003 |
Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Dominance, Cerebral; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Thalamus | 2003 |
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Net; Prefrontal Cortex; Psychotic Disorders; Reference Values; Risk; Schizophrenia; Schizotypal Personality Disorder; Temporal Lobe | 2003 |
1H MRSI evidence of metabolic abnormalities in childhood-onset schizophrenia.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Mapping; Caudate Nucleus; Child; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Frontal Lobe; Gyrus Cinguli; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Phosphocreatine; Reference Values; Schizophrenia; Schizophrenic Psychology; Sex Factors; Thalamus | 2004 |
Duration of untreated psychosis vs. N-acetylaspartate and choline in first episode schizophrenia: a 1H magnetic resonance spectroscopy study at 4.0 Tesla.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Cell Death; Choline; Cohort Studies; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Schizophrenic Psychology; Schizotypal Personality Disorder; Statistics as Topic; Time Factors | 2004 |
Relationship between performance on the Stroop test and N-acetylaspartate in the medial prefrontal cortex in deficit and nondeficit schizophrenia: preliminary results.
Topics: Aspartic Acid; Cognition Disorders; Humans; Neuropsychological Tests; Prefrontal Cortex; Schizophrenia; Severity of Illness Index | 2004 |
Evidence for glutamatergic neuronal dysfunction in the prefrontal cortex in chronic but not in first-episode patients with schizophrenia: a proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Chronic Disease; Diagnostic and Statistical Manual of Mental Disorders; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Protons; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Synaptic Transmission | 2005 |
Further evidence for altered cerebellar neuronal integrity in schizophrenia.
Topics: Adult; Aspartic Acid; Cerebellar Cortex; Cerebellum; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Neurons; Pons; Schizophrenia; Thalamus | 2005 |
N-acetylaspartate reductions in the mediodorsal and anterior thalamus in men with schizophrenia verified by tissue volume corrected proton MRSI.
Topics: Adult; Anterior Thalamic Nuclei; Aspartic Acid; Choline; Creatine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mediodorsal Thalamic Nucleus; Protons; Schizophrenia | 2005 |
Comment on "N-acetylaspartate reductions in the mediodorsal and anterior thalamus in men with schizophrenia verified by tissue volume corrected proton MRSI" (Schizophr Res 76, 173-185, 2005).
Topics: Anterior Thalamic Nuclei; Aspartic Acid; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Mediodorsal Thalamic Nucleus; Schizophrenia | 2006 |
Proton magnetic resonance spectroscopy of the anterior cingulate gyrus, insular cortex and thalamus in schizophrenia associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome).
Topics: Adult; Aspartic Acid; Cerebral Cortex; Choline; Female; Gilbert Disease; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Thalamus | 2005 |
Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate measures in the dorsolateral prefrontal cortex.
Topics: Aspartic Acid; Creatine; Female; Functional Laterality; Genetic Predisposition to Disease; Genotype; Heterozygote; Humans; Introns; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Polymorphism, Single Nucleotide; Prefrontal Cortex; Psychiatric Status Rating Scales; Receptors, Metabotropic Glutamate; Schizophrenia | 2006 |
Excitatory aminoacid neurotransmitters in schizophrenia.
Topics: Adolescent; Adult; Aspartic Acid; Bangladesh; Case-Control Studies; Disease Progression; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Male; Middle Aged; Schizophrenia | 2005 |
Quantitative magnetic resonance spectroscopy of schizophrenia: relationship between decreased N-acetylaspartate and frontal lobe dysfunction.
Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Schizophrenic Psychology | 2006 |
Regulation of NAA-synthesis in the human brain in vivo: Canavan's disease, Alzheimer's disease and schizophrenia.
Topics: Alzheimer Disease; Aspartic Acid; Brain; Canavan Disease; Child; Glutamic Acid; Humans; Magnetic Resonance Imaging; Molecular Structure; Schizophrenia | 2006 |
Proton magnetic resonance spectroscopy in subjects at risk for schizophrenia.
Topics: Adult; Aspartic Acid; Choline; Female; Frontal Lobe; Gyrus Cinguli; Humans; Interview, Psychological; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Risk Assessment; Schizophrenia; Temporal Lobe | 2006 |
Cognitive impairment and in vivo metabolites in first-episode neuroleptic-naive and chronic medicated schizophrenic patients: a proton magnetic resonance spectroscopy study.
Topics: Adult; Aged; Antipsychotic Agents; Aspartic Acid; Choline; Chronic Disease; Cognition Disorders; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Recall; Middle Aged; Neurons; Phosphocreatine; Prefrontal Cortex; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Verbal Learning | 2007 |
Regarding "Increased prefrontal and hippocampal glutamate concentration in schizophrenia: evidence from a magnetic resonance spectroscopy study".
Topics: Aspartic Acid; Choline; Creatine; Dominance, Cerebral; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Phosphocreatine; Prefrontal Cortex; Reference Values; Schizophrenia; Thalamus | 2007 |
Prediction of functional outcome 18 months after a first psychotic episode: a proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Follow-Up Studies; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Outcome Assessment, Health Care; Patient Readmission; Phosphocreatine; Predictive Value of Tests; Prefrontal Cortex; Prognosis; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Temporal Lobe | 2006 |
No association between dorsolateral prefrontal gray matter deficit and N-acetyl aspartate ratios in schizophrenia.
Topics: Adult; Aspartic Acid; Cerebrospinal Fluid; Extracellular Fluid; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Organ Size; Prefrontal Cortex; Schizophrenia; Statistics, Nonparametric | 2006 |
Tryptophan breakdown pathway in bipolar mania.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Brief Psychiatric Rating Scale; Female; Gyrus Cinguli; Humans; Kynurenic Acid; Kynurenine; Male; Schizophrenia; Severity of Illness Index; Tryptophan | 2007 |
Further evidence for altered myelin biosynthesis and glutamatergic dysfunction in schizophrenia.
Topics: Adult; Aged; Amidohydrolases; Aspartic Acid; Cadaver; Case-Control Studies; Fatty Acids; Female; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Male; Middle Aged; Myelin Sheath; Oligodendroglia; Prefrontal Cortex; Receptors, Metabotropic Glutamate; RNA, Messenger; Schizophrenia; Synaptic Transmission | 2007 |
The neuronal pathology of schizophrenia: molecules and mechanisms.
Topics: Animals; Aspartic Acid; Brain; Corpus Striatum; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; Neurons; Phencyclidine; Schizophrenia | 2007 |
Failure to confirm the association between the FEZ1 gene and schizophrenia in a Japanese population.
Topics: Adaptor Proteins, Signal Transducing; Adult; Amino Acid Substitution; Asian People; Aspartic Acid; Brain; Brain Chemistry; DNA Mutational Analysis; DNA-Binding Proteins; Female; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glutamic Acid; Humans; Japan; Male; Middle Aged; Mutation; Mutation, Missense; Nerve Tissue Proteins; Polymorphism, Genetic; Schizophrenia; Tumor Suppressor Proteins | 2007 |
Reduced N-acetyl-aspartate levels in schizophrenia patients with a younger onset age: a single-voxel 1H spectroscopy study.
Topics: Adult; Age of Onset; Aspartic Acid; Cell Division; Dendrites; Dominance, Cerebral; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Reference Values; Schizophrenia; Synapses | 2007 |
Relationship between frontal N-acetylaspartate and cognitive deficits in first-episode schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Cognition Disorders; Female; Frontal Lobe; Humans; Male; Neuropsychological Tests; Schizophrenia | 2007 |
N-acetylaspartate (NAA) levels in selected areas of the brain in patients with chronic schizophrenia treated with typical and atypical neuroleptics: a proton magnetic resonance spectroscopy (1H MRS) study.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain; Female; Humans; Magnetic Resonance Imaging; Male; Schizophrenia | 2007 |
Association study of polymorphisms in the mitochondrial aspartate/glutamate carrier SLC25A12 (aralar) gene with schizophrenia.
Topics: Adult; Aspartic Acid; Brain Chemistry; Case-Control Studies; Female; Genotype; Haplotypes; Humans; Linkage Disequilibrium; Magnetic Resonance Imaging; Male; Membrane Transport Proteins; Middle Aged; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Polymorphism, Genetic; Schizophrenia | 2007 |
Dorsolateral prefrontal N-acetyl-aspartate concentration in male patients with chronic schizophrenia and with chronic bipolar disorder.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Cerebrospinal Fluid; Choline; Chronic Disease; Creatine; Fourier Analysis; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Prefrontal Cortex; Reference Values; Schizophrenia | 2007 |
The effect of clozapine on neuroimaging findings in schizophrenia.
Topics: Aged, 80 and over; Antipsychotic Agents; Aspartic Acid; Brain; Choline; Clozapine; Creatine; Energy Metabolism; Humans; Magnetic Resonance Spectroscopy; Neuropsychological Tests; Prognosis; Psychiatric Status Rating Scales; Regional Blood Flow; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2007 |
Magnetic resonance imaging and spectroscopy in a mouse model of schizophrenia.
Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Disease Models, Animal; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Protons; Schizophrenia | 2008 |
A 1H-MRS investigation of the medial temporal lobe in antipsychotic-naïve and early-treated first episode psychosis.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Female; Frontal Lobe; Functional Laterality; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Psychotic Disorders; Schizophrenia; Temporal Lobe | 2008 |
Altered metabolic integrity of corpus callosum among individuals at ultra high risk of schizophrenia and first-episode patients.
Topics: Adult; Aspartic Acid; Case-Control Studies; Corpus Callosum; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Psychiatric Status Rating Scales; Risk; Schizophrenia; Young Adult | 2008 |
Serial proton magnetic resonance spectroscopy in a patient with acute carbon monoxide poisoning.
Topics: Adult; Aspartic Acid; Carbon Monoxide Poisoning; Carboxyhemoglobin; Choline; Creatine; Energy Metabolism; Female; Follow-Up Studies; Frontal Lobe; Humans; Hyperbaric Oxygenation; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Reference Values; Regional Blood Flow; Schizophrenia; Schizophrenic Psychology; Suicide, Attempted; Tomography, Emission-Computed, Single-Photon; Wechsler Scales | 1995 |
Analysis of the conserved Asp(114) residue of the dopamine D2 receptor in schizophrenic patients.
Topics: Aspartic Acid; Base Sequence; Binding Sites; Chlorpromazine; Drug Resistance; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Protein Binding; Protein Structure, Tertiary; Receptors, Dopamine D2; Schizophrenia | 1994 |
Proton magnetic resonance spectroscopy (1H MRS) of the hippocampal formation in schizophrenia: a pilot study.
Topics: Adult; Aspartic Acid; Female; Functional Laterality; Hippocampus; Humans; Hydrogen; Limbic System; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Schizophrenia | 1994 |
Tardive dyskinesia and substrates of energy metabolism in CSF.
Topics: Adult; Alanine; Antipsychotic Agents; Aspartic Acid; Citric Acid Cycle; Dyskinesia, Drug-Induced; Energy Metabolism; Female; Humans; Lactates; Male; Middle Aged; Mitochondria; Oxidative Phosphorylation; Pyruvates; Schizophrenia | 1995 |
Proton magnetic resonance spectroscopy of the left medial temporal and frontal lobes in chronic schizophrenia: preliminary report.
Topics: Adult; Arousal; Aspartic Acid; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurocognitive Disorders; Phosphocreatine; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Schizophrenic Psychology; Temporal Lobe | 1995 |
Proton magnetic resonance spectroscopy of basal ganglia in chronic schizophrenia.
Topics: Adult; Aspartic Acid; Basal Ganglia; Basal Ganglia Diseases; Brain Mapping; Choline; Chronic Disease; Creatine; Dominance, Cerebral; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurocognitive Disorders; Phosphocreatine; Protons; Psychiatric Status Rating Scales; Schizophrenia | 1996 |
Hippocampal age-related changes in schizophrenia: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Age Factors; Aging; Aspartic Acid; Choline; Creatine; Female; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Degeneration; Schizophrenia | 1996 |
Proton magnetic resonance spectroscopy of the basal ganglia in patients with schizophrenia: a preliminary report.
Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Choline; Creatine; Educational Status; Female; Functional Laterality; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Schizophrenia | 1996 |
An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients.
Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1996 |
Regionally specific pattern of neurochemical pathology in schizophrenia as assessed by multislice proton magnetic resonance spectroscopic imaging.
Topics: Adult; Aspartic Acid; Brain; Choline; Creatinine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Prefrontal Cortex; Protons; Schizophrenia | 1996 |
Gly(247)-->Asp proenkephalin A mutation is rare in schizophrenia populations.
Topics: Aspartic Acid; Enkephalins; Female; Glycine; Humans; Male; Mutation; Protein Precursors; Schizophrenia | 1997 |
Decreased left frontal lobe N-acetylaspartate in schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Biomarkers; Cell Count; Choline; Creatine; Female; Functional Laterality; Gliosis; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Pilot Projects; Schizophrenia; Temporal Lobe | 1997 |
In vitro 1H-magnetic resonance spectroscopy of postmortem brains with schizophrenia.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain Chemistry; Cerebellum; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Thalamus | 1997 |
Deficits of [3H]D-aspartate binding to glutamate uptake sites in striatal and accumbens tissue in patients with schizophrenia.
Topics: Aged; Animals; Aspartic Acid; Corpus Striatum; Female; Frontal Lobe; Glutamic Acid; Humans; Male; Middle Aged; Nucleus Accumbens; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glutamate; Schizophrenia; Synaptic Membranes; Tritium | 1997 |
Detection of two new polymorphic sites in the human interleukin-1 beta gene: lack of association with schizophrenia in a French population.
Topics: Adult; Alleles; Amino Acid Substitution; Asparagine; Aspartic Acid; Exons; Female; France; Gene Frequency; Genotype; Humans; Interleukin-1; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Restriction Mapping; Schizophrenia; Sequence Deletion | 1997 |
Glutamate receptors in the postmortem striatum of schizophrenic, suicide, and control brains.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Antipsychotic Agents; Aspartic Acid; Autoradiography; Basal Ganglia; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Humans; Kainic Acid; Male; Middle Aged; Neostriatum; Receptors, AMPA; Receptors, Glutamate; Schizophrenia; Suicide | 1997 |
Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Educational Status; Female; Functional Laterality; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Schizophrenia; Sex Factors; Tomography, Emission-Computed | 1997 |
Proton magnetic resonance spectroscopy of the anterior cingulate region in schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Brain Mapping; Choline; Creatine; Dominance, Cerebral; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1997 |
Clozapine treatment increases serum glutamate and aspartate compared to conventional neuroleptics.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Clozapine; Female; Glutamic Acid; Humans; Linear Models; Male; Middle Aged; Schizophrenia | 1997 |
Proton magnetic resonance spectroscopic imaging of cortical gray and white matter in schizophrenia.
Topics: Adult; Age of Onset; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Educational Status; Humans; Intelligence; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia | 1998 |
Absence of basal ganglia amino acid neuron deficits in schizophrenia in three collections of brains.
Topics: Aged; Amino Acid Transport System X-AG; Analysis of Variance; Aspartic Acid; ATP-Binding Cassette Transporters; Basal Ganglia; Binding Sites; Carrier Proteins; Case-Control Studies; GABA Plasma Membrane Transport Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Nipecotic Acids; Organic Anion Transporters; Phencyclidine; Proline; Radioligand Assay; Schizophrenia; Tritium | 1998 |
Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Biomarkers; Corpus Striatum; Dipeptides; Dopamine Antagonists; Dyskinesia, Drug-Induced; Female; Glutamates; Humans; Lipid Peroxides; Male; Middle Aged; Neuropeptides; Oxidative Stress; Psychiatric Status Rating Scales; Receptors, Dopamine; Schizophrenia; Superoxide Dismutase; Synaptic Transmission | 1998 |
Common pattern of cortical pathology in childhood-onset and adult-onset schizophrenia as identified by proton magnetic resonance spectroscopic imaging.
Topics: Adolescent; Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Prefrontal Cortex; Protons; Schizophrenia; Schizophrenia, Childhood | 1998 |
Comparison of glutamate and gamma-aminobutyric acid uptake binding sites in frontal and temporal lobes in schizophrenia.
Topics: Aged; Aspartic Acid; Chronic Disease; Female; Frontal Lobe; Humans; Male; Middle Aged; Nipecotic Acids; Proline; Receptors, GABA; Receptors, Glutamate; Schizophrenia; Temporal Lobe | 1998 |
Regional proton magnetic resonance spectroscopy in schizophrenia and exploration of drug effect.
Topics: Adult; Aged; Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Basal Ganglia; Brain; Case-Control Studies; Choline; Creatine; Frontal Lobe; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Temporal Lobe; Thalamus | 1998 |
The role of prefrontal cortex in the dopaminergic dysregulation of schizophrenia.
Topics: Aspartic Acid; Dopamine; Humans; Magnetic Resonance Spectroscopy; Prefrontal Cortex; Presynaptic Terminals; Schizophrenia; Stress, Psychological; Tomography, Emission-Computed, Single-Photon | 1999 |
The relationship between dorsolateral prefrontal N-acetylaspartate measures and striatal dopamine activity in schizophrenia.
Topics: Adult; Animals; Aspartic Acid; Choline; Chronic Disease; Corpus Striatum; Creatinine; Dopamine; Female; Humans; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1999 |
A short echo proton magnetic resonance spectroscopy study of the left mesial-temporal lobe in first-onset schizophrenic patients.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Case-Control Studies; Female; Fourier Analysis; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Protons; Schizophrenia; Temporal Lobe | 1999 |
Reduced hippocampal N-acetylaspartate without volume loss in schizophrenia.
Topics: Adult; Aspartic Acid; Cell Death; Chronic Disease; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Neuroglia; Neurons; Schizophrenia | 1999 |
Distributed disturbances in brain structure and function in schizophrenia.
Topics: Aspartic Acid; Brain; Humans; Magnetic Resonance Spectroscopy; Models, Neurological; Neural Pathways; Neurotransmitter Agents; Schizophrenia; Tomography, Emission-Computed | 2000 |
The relationship between dorsolateral prefrontal neuronal N-acetylaspartate and evoked release of striatal dopamine in schizophrenia.
Topics: Adult; Amphetamine; Aspartic Acid; Carbon Radioisotopes; Corpus Striatum; Dopamine; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Raclopride; Reference Values; Schizophrenia; Tomography, Emission-Computed | 2000 |
Heritability heightens brain metabolite differences in schizophrenia.
Topics: Adult; Aspartic Acid; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Genetic Predisposition to Disease; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Reference Values; Schizophrenia; Temporal Lobe | 2000 |
Subtype-associated metabolite differences in the temporal lobe in schizophrenia detected by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain Mapping; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Humans; Inositol; Magnetic Resonance Spectroscopy; Schizophrenia; Schizophrenia, Disorganized; Schizophrenia, Paranoid; Temporal Lobe | 1999 |
Effects of age, medication, and illness duration on the N-acetyl aspartate signal of the anterior cingulate region in schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Clozapine; Creatine; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Reference Values; Risperidone; Schizophrenia; Treatment Outcome | 2000 |
Proton magnetic resonance spectroscopy of the medial prefrontal cortex in patients with deficit schizophrenia: preliminary report.
Topics: Aspartic Acid; Cell Count; Creatine; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Neurons; Phosphocreatine; Prefrontal Cortex; Radionuclide Imaging; Schizophrenia; Schizophrenic Psychology | 2000 |
Reduced concentrations of thalamic N-acetylaspartate in male patients with schizophrenia.
Topics: Adult; Aspartic Acid; Cell Count; Choline; Creatine; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Schizophrenia; Sex Factors; Thalamus | 2000 |
Thalamic abnormalities in patients with schizophrenia revealed by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Creatine; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Thalamus | 2000 |
Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies.
Topics: Adult; Aspartic Acid; Case-Control Studies; Dominance, Cerebral; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Schizophrenia | 2000 |
Schizophrenia, temporal lobe epilepsy and psychosis: an in vivo magnetic resonance spectroscopy and imaging study of the hippocampus/amygdala complex.
Topics: Adult; Amygdala; Aspartic Acid; Case-Control Studies; Epilepsy, Temporal Lobe; Female; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychotic Disorders; Schizophrenia | 2000 |
Decreased frontal lobe ratio of N-acetyl aspartate to choline in familial schizophrenia: a proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Basal Ganglia; Choline; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Protons; Schizophrenia | 2000 |
Selective relationship between prefrontal N-acetylaspartate measures and negative symptoms in schizophrenia.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Female; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology | 2000 |
Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited.
Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Female; Humans; Magnetic Resonance Imaging; Male; Memory; Prefrontal Cortex; Schizophrenia | 2000 |
Proton magnetic resonance spectroscopy (1H-MRS) of the cerebellum in men with schizophrenia.
Topics: Adult; Aspartic Acid; Cerebellum; Choline; Creatine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Schizophrenia | 2000 |
Diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy (1H MRS) in schizophrenic subjects and normal controls.
Topics: Adult; Anisotropy; Aspartic Acid; Brain; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Prefrontal Cortex; Protons; Schizophrenia; Temporal Lobe | 2001 |
Lower concentration of thalamic n-acetylaspartate in patients with schizophrenia: a replication study.
Topics: Adult; Aspartic Acid; Choline; Female; Functional Laterality; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Schizophrenia; Thalamus | 2001 |
Reduced NAA in the thalamus and altered membrane and glial metabolism in schizophrenic patients detected by 1H-MRS and tissue segmentation.
Topics: Adult; Aspartic Acid; Atrophy; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuroglia; Parietal Lobe; Psychiatric Status Rating Scales; Reference Values; Schizophrenia; Synaptic Membranes; Thalamus | 2001 |
High choline concentrations in the caudate nucleus in antipsychotic-naive patients with schizophrenia.
Topics: Adult; Aspartic Acid; Caudate Nucleus; Choline; Creatine; Dominance, Cerebral; Female; Humans; Magnetic Resonance Spectroscopy; Male; Reference Values; Schizophrenia | 2002 |
Functioning and neuronal viability of the anterior cingulate neurons following antipsychotic treatment: MR-spectroscopic imaging in chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Cell Survival; Chronic Disease; Cross-Sectional Studies; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Neuropsychological Tests; Schizophrenia | 2002 |
Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia.
Topics: Adult; Aged; Alanine; Animals; Antipsychotic Agents; Aspartic Acid; Biogenic Polyamines; Female; Gene Expression; Gene Expression Profiling; Haloperidol; Humans; In Situ Hybridization; Logistic Models; Macaca fascicularis; Malates; Male; Middle Aged; Mitochondria; Oligonucleotide Array Sequence Analysis; Ornithine; Prefrontal Cortex; Schizophrenia; Ubiquitin | 2002 |
Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Phosphates; Phosphocreatine; Protons; Schizophrenia; Schizophrenic Psychology | 1992 |
Regionally selective deficits in uptake sites for glutamate and gamma-aminobutyric acid in the basal ganglia in schizophrenia.
Topics: Aspartic Acid; Brain; Caudate Nucleus; Dominance, Cerebral; gamma-Aminobutyric Acid; Globus Pallidus; Glutamates; Glutamic Acid; Humans; Nipecotic Acids; Nucleus Accumbens; Proline; Putamen; Radioligand Assay; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Schizophrenia; Schizophrenic Psychology | 1992 |
Evidence of glutamatergic deficiency in schizophrenia.
Topics: Aged; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Haloperidol; Humans; In Vitro Techniques; Male; Middle Aged; Schizophrenia; Synaptosomes; Veratridine | 1991 |
Determination of N-acetylaspartic acid in human cerebrospinal fluid by gas chromatography-mass spectrometry.
Topics: Adult; Aspartic Acid; Chromatography, Gas; Esters; Female; Humans; Male; Mass Spectrometry; Middle Aged; Osmolar Concentration; Reference Values; Schizophrenia; Subarachnoid Hemorrhage | 1990 |
Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia.
Topics: Aspartic Acid; Dopamine; Frontal Lobe; Glutamates; Glutamic Acid; Humans; Schizophrenia; Temporal Lobe | 1989 |
Use of the polyethylene glycol adduct of L-asparaginase for the treatment of hyperasparaginemia in a schizophrenic patient.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Asparaginase; Asparagine; Aspartic Acid; Brain; Humans; Male; Polyethylene Glycols; Schizophrenia | 1985 |