Compounds > aspartic acid
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aspartic acid and Chemical and Drug Induced Liver Injury

aspartic acid has been researched along with Chemical and Drug Induced Liver Injury in 25 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
"Liver necrosis was produced in rats by administering 3 doses of a mixture of carbon tetrachloride + olive oil, 2 ml/kg, ip."3.68Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats. ( Garg, KN; Mehrotra, GC; Singh, J, 1990)
"majus) methyl alcohol extract and vitamin E in the case of toxic effect induced by diethyl maleate was evaluated."1.36The protective role of Tropaeolum majus on blood and liver toxicity induced by diethyl maleate in rats. ( Arbid, MS; El-Gendy, NF; Koriem, KM, 2010)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199018 (72.00)18.7374
1990's4 (16.00)18.2507
2000's0 (0.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Reznik, EV1
Yudin, DV1
Gudilova, YY1
Baikova, IE1
Karmanova, SE1
Nikitin, IG1
Farooq, A2
Hoque, R1
Ouyang, X1
Ghani, A1
Ahsan, K1
Guerra, M1
Mehal, WZ1
Koriem, KM1
Arbid, MS1
El-Gendy, NF1
MASUDA, M1
KUZUDANI, A1
MORI, K1
OGASAWARA, K1
IRINO, J1
TABUCHI, K1
TOMIKAWA, J1
INOUE, H1
NAKANO, K1
ADACHI, H1
KANETSUNA, H1
RATSIMAMANGA, AR1
HALLER, PH1
SHIOYA, A1
KURAISHI, K1
KAKIMOTO, M1
TAMAMA, Y1
SALVATORE, F1
CIMINO, F1
DAYELLO CARACCIOLO, M1
CITTADINI, D1
Strolin Benedetti, M1
Rumigny, JF1
Dostert, P1
Dudley, RE1
Klaassen, CD1
Ohta, Y1
Sasaki, E1
Nishida, K1
Kobayashi, T1
Nagata, M1
Ishiguro, I1
Schieber, A1
Brückner, H1
Rupp-Classen, M1
Specht, W1
Nowitzki-Grimm, S1
Classen, HG1
Fodor, O5
Schvartz, M1
Suciu, A1
Barbarino, F4
Duca, S1
Lezeu, R1
Kurysheva, NG1
Ekshtat, BIa1
Kazanina, SS1
Stenram, U1
Singh, J1
Garg, KN1
Mehrotra, GC1
Cooney, DA1
Yavelow, J1
Zlotoff, R1
Bergenstal, R1
Burg, A1
Morrison, R1
Fleischman, R1
Tăpălagă, D3
Cotuţiu, C2
Streja, D1
Nicoara, A1
Gajdos, A1
Ripamonti, C1
Record, CO1
Alberti, KG1
Williamson, DH1
Raab, WP1
Parau, N2
Calu, C2
Ban, A2

Reviews

1 review available for aspartic acid and Chemical and Drug Induced Liver Injury

ArticleYear
[Mechanisms of action and biochemical toxicology of valproic acid].
    L'Encephale, 1984, Volume: 10, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Ammonia; Animals; Anticonvulsants; Aspartic

1984

Trials

1 trial available for aspartic acid and Chemical and Drug Induced Liver Injury

ArticleYear
[Controlled clinical trial of a new substance with hepatotropic activity, carried out with an experimental cross-over plan in double-blind conditions].
    La Clinica terapeutica, 1972, Jul-15, Volume: 62, Issue:1

    Topics: Adult; Aged; Alcoholism; Amino Acids; Aspartic Acid; Chemical and Drug Induced Liver Injury; Chronic

1972

Other Studies

23 other studies available for aspartic acid and Chemical and Drug Induced Liver Injury

ArticleYear
[A medicinal liver injury with an immunomodulatory drug of natural origin. Case report].
    Terapevticheskii arkhiv, 2021, Aug-15, Volume: 93, Issue:8

    Topics: Adjuvants, Immunologic; Adult; Alanine; Alkaline Phosphatase; Aspartic Acid; Bilirubin; Chemical and

2021
Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Oct-01, Volume: 307, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arrestins; Aspartic Acid; beta-Arrestin 2; beta-Arrestins; Carrie

2014
The protective role of Tropaeolum majus on blood and liver toxicity induced by diethyl maleate in rats.
    Toxicology mechanisms and methods, 2010, Volume: 20, Issue:9

    Topics: Alanine Transaminase; Animals; Aspartic Acid; Chemical and Drug Induced Liver Injury; Lethal Dose 50

2010
[STUDIES ON ASPARTIC ACID SALTS. II. BASIC STUDIES].
    [Sogo rinsho] Clinic all-round, 1964, Volume: 13

    Topics: Ammonia; Aspartic Acid; Biomedical Research; Carbon Tetrachloride Poisoning; Chemical and Drug Induc

1964
[PHARMACOLOGY OF A NEW ANTITOXIC PRINCIPLE].
    Gazette medicale de France, 1964, Apr-10, Volume: 71

    Topics: Amino Acids; Aspartic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury;

1964
PHARMACOLOGICAL STUDY ON L-ORNITHINE L-ASPARTATE.
    Japanese journal of pharmacology, 1964, Volume: 14

    Topics: Alanine Transaminase; Ammonia; Ammonium Chloride; Aspartate Aminotransferases; Aspartic Acid; Blood;

1964
MECHANISM OF THE PROTECTION BY L-ORNITHINE-L-ASPARTATE MIXTURE AND BY L-ARGININE IN AMMONIA INTOXICATION.
    Archives of biochemistry and biophysics, 1964, Volume: 107

    Topics: Ammonia; Arginine; Aspartic Acid; Chemical and Drug Induced Liver Injury; Dipeptides; Hepatitis; Lig

1964
Changes in hepatic glutathione concentration modify cadmium-induced hepatotoxicity.
    Toxicology and applied pharmacology, 1984, Mar-15, Volume: 72, Issue:3

    Topics: Alanine; Animals; Aspartic Acid; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Cysteine

1984
Preventive effect of dai-saiko-to (da-chai-hu-tang) extract on disrupted hepatic active oxygen metabolism in rats with carbon tetrachloride-induced liver injury.
    The American journal of Chinese medicine, 1995, Volume: 23, Issue:1

    Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartic Acid; Carbon Tetrachloride; Chemical a

1995
Evaluation of D-amino acid levels in rat by gas chromatography-selected ion monitoring mass spectrometry: no evidence for subacute toxicity of orally fed D-proline and D-aspartic acid.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Mar-28, Volume: 691, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Chemical and Drug Induced Liver Injury; Female

1997
Protecting action of aspartate on the hepatic changes induced by D-galactosamine.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:5

    Topics: Adenosine Triphosphatases; Alanine Transaminase; Alcohol Oxidoreductases; Animals; Aspartate Aminotr

1976
[Mechanism of the hepatotropic action of 1,1,2,3-tetrachlorpropene].
    Gigiena i sanitariia, 1977, Issue:4

    Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Chemical and Dru

1977
Hepatotoxicity of fluorouracil with N-phosphonacetyl-L-aspartate.
    Annals of internal medicine, 1992, Jul-01, Volume: 117, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Chemical and Drug Induced Liver Injur

1992
Effect of aspartate and glutamate on carbon tetrachloride induced liver damage in rats.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:12

    Topics: Animals; Aspartic Acid; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Glutamates; Li

1990
Azotomycin--toxicologic, biochemical and pharmacologic studies in mice.
    Biochemical pharmacology, 1974, Dec-15, Volume: 23, Issue:24

    Topics: Animals; Antibiotics, Antineoplastic; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Ataxia

1974
[Histoenzymatic changes under the protective and therapeutic action of aspartic acid in experimental toxic hepatitis].
    Studii si cercetari de medicina interna, 1967, Volume: 8, Issue:6

    Topics: Acid Phosphatase; Adenosine Triphosphatases; Animals; Aspartic Acid; Carbon Tetrachloride Poisoning;

1967
[Study of B.S.P. metabolites and some histo-enzymologic modifications under the influence of aspartic acid].
    Revue internationale d'hepatologie, 1967, May-28, Volume: 17, Issue:6

    Topics: Acid Phosphatase; Adenosine Triphosphatases; Amino Acids; Animals; Asparagine; Aspartic Acid; Biliru

1967
Protective action of the aspartic acid on liver steroid dehydrogenases in experimental chronic intoxication with carbon tetrachloride.
    Acta gastro-enterologica Belgica, 1971, Volume: 34, Issue:6

    Topics: Adenosine Triphosphatases; Animals; Aspartic Acid; Carbon Tetrachloride Poisoning; Chemical and Drug

1971
[The metabolism of ethanol. I. Hepatic oxidation of ethanol. Its biochemical action on the liver].
    Annales de biologie clinique, 1974, Volume: 32, Issue:5

    Topics: Alcohol Oxidoreductases; Alcoholic Intoxication; Animals; Aspartic Acid; Carbohydrate Metabolism; Ca

1974
Metabolic studies in experimental liver disease resulting from D(+)-galactosamine administration.
    The Biochemical journal, 1972, Volume: 130, Issue:1

    Topics: Acetoacetates; Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; C

1972
Experimental liver damage in potassium depletion, inhibited by L-ornithine-L-aspartate.
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Chemical and Drug Induced

1971
[New data on the protective action of aspartic acid in experimental toxic hepatitis, assessed by the determination of blood and tissue enzymes of the liver].
    Revue internationale d'hepatologie, 1965, Volume: 15, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Blood; Carbon Tetrachlori

1965
[Further aspects of the protective action of aspartic acid in experimental toxic hepatitis studied by determination of serum and liver tissue enzymes].
    Medicina interna, 1965, Volume: 17, Issue:7

    Topics: Animals; Aspartic Acid; Chemical and Drug Induced Liver Injury; Liver; Rabbits; Transferases

1965