aspartic acid has been researched along with Cerebrovascular Disorders in 35 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using high-performance liquid chromatography, we determined the glutamate, aspartate, taurine, and glycine concentrations in the plasma and cerebrospinal fluid (CSF) of 128 patients with ischemic cerebral infarction confirmed by CT and 43 control subjects." | 3.69 | Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke. ( Castillo, J; Dávalos, A; Naveiro, J; Noya, M, 1996) |
| "Diabetes and hypertension are potent risk factors for cerebrovascular disease." | 1.33 | Diabetic brain damage in hypertension: role of renin-angiotensin system. ( Eguchi, K; Hoshide, S; Ishikawa, J; Ishikawa, S; Kario, K; Matsui, Y; Morinari, M; Shimada, K, 2005) |
| "Choline levels were unchanged in the lesions." | 1.29 | Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions. ( Barker, PB; Bryan, RN; Conturo, TE; Oppenheimer, SM; Preziosi, TJ; Soher, BJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.29) | 18.7374 |
| 1990's | 22 (62.86) | 18.2507 |
| 2000's | 5 (14.29) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wagner, M | 1 |
| Jurcoane, A | 1 |
| Hildebrand, C | 1 |
| Güresir, E | 1 |
| Vatter, H | 1 |
| Zanella, FE | 1 |
| Berkefeld, J | 1 |
| Pilatus, U | 1 |
| Hattingen, E | 1 |
| Niu, XQ | 1 |
| Zhao, XX | 1 |
| Li, BC | 1 |
| Gao, YJ | 1 |
| Xu, W | 1 |
| Fan, YD | 1 |
| Fu, GP | 1 |
| Wang, K | 1 |
| Pu, J | 1 |
| Nitkunan, A | 1 |
| Charlton, RA | 1 |
| Barrick, TR | 1 |
| McIntyre, DJ | 1 |
| Howe, FA | 1 |
| Markus, HS | 1 |
| Kantarci, K | 2 |
| Petersen, RC | 2 |
| Przybelski, SA | 2 |
| Weigand, SD | 2 |
| Shiung, MM | 2 |
| Whitwell, JL | 2 |
| Negash, S | 2 |
| Ivnik, RJ | 1 |
| Boeve, BF | 2 |
| Knopman, DS | 2 |
| Smith, GE | 1 |
| Jack, CR | 2 |
| O'Brien, PC | 1 |
| Lundin, F | 1 |
| Tisell, A | 1 |
| Dahlqvist Leinhard, O | 1 |
| Tullberg, M | 1 |
| Wikkelsö, C | 1 |
| Lundberg, P | 1 |
| Leijon, G | 1 |
| Kario, K | 1 |
| Ishikawa, J | 1 |
| Hoshide, S | 1 |
| Matsui, Y | 1 |
| Morinari, M | 1 |
| Eguchi, K | 1 |
| Ishikawa, S | 1 |
| Shimada, K | 1 |
| Bullock, R | 1 |
| Zauner, A | 1 |
| Woodward, J | 1 |
| Young, HF | 1 |
| Kamada, K | 2 |
| Houkin, K | 2 |
| Iwasaki, Y | 2 |
| Abe, H | 2 |
| Kashiwaba, T | 1 |
| Mathews, VP | 1 |
| Barker, PB | 3 |
| Blackband, SJ | 1 |
| Chatham, JC | 1 |
| Bryan, RN | 3 |
| Blamire, AM | 2 |
| Graham, GD | 2 |
| Rothman, DL | 2 |
| Prichard, JW | 2 |
| Oppenheimer, SM | 2 |
| Conturo, TE | 1 |
| Soher, BJ | 1 |
| Preziosi, TJ | 1 |
| Hida, K | 1 |
| Matsuzawa, H | 1 |
| Nakada, T | 1 |
| Adalsteinsson, E | 1 |
| Spielman, DM | 1 |
| Wright, GA | 1 |
| Pauly, JM | 1 |
| Meyer, CH | 1 |
| Macovski, A | 1 |
| Castillo, J | 1 |
| Dávalos, A | 1 |
| Naveiro, J | 1 |
| Noya, M | 1 |
| Marshall, I | 3 |
| Wardlaw, J | 1 |
| Cannon, J | 2 |
| Slattery, J | 1 |
| Sellar, RJ | 1 |
| Gillard, JH | 1 |
| van Zijl, PC | 1 |
| Wild, JM | 1 |
| Ema, M | 1 |
| Gebrewold, A | 2 |
| Altura, BT | 2 |
| Zhang, A | 1 |
| Altura, BM | 2 |
| Wardlaw, JM | 1 |
| Wild, J | 1 |
| Dennis, MS | 1 |
| Lewis, SC | 1 |
| Cai, H | 1 |
| Wang, X | 1 |
| Colagiuri, S | 1 |
| Wilcken, DE | 1 |
| Stevens, H | 1 |
| Jakobs, C | 1 |
| de Jager, AE | 1 |
| Cunningham, RT | 1 |
| Korf, J | 1 |
| MacLeod, MJ | 1 |
| Dahiyat, MT | 1 |
| Cumming, A | 1 |
| Meiklejohn, D | 1 |
| Shaw, D | 1 |
| St Clair, D | 1 |
| Chan, YL | 1 |
| Roebuck, DJ | 1 |
| Yuen, MP | 1 |
| Yeung, KW | 1 |
| Lau, KY | 1 |
| Li, CK | 1 |
| Chik, KW | 1 |
| Garcia, JH | 1 |
| Lossinsky, AS | 1 |
| Kauffman, FC | 1 |
| Conger, KA | 1 |
| Wang, Z | 1 |
| Bogdan, AR | 1 |
| Zimmerman, RA | 1 |
| Gusnard, DA | 1 |
| Leigh, JS | 1 |
| Ohene-Frempong, K | 1 |
| Gideon, P | 1 |
| Henriksen, O | 1 |
| Sperling, B | 1 |
| Christiansen, P | 1 |
| Olsen, TS | 1 |
| Jørgensen, HS | 1 |
| Arlien-Søborg, P | 1 |
| Howseman, AM | 1 |
| Fayad, PB | 1 |
| Brass, LM | 1 |
| Petroff, OA | 1 |
| Shulman, RG | 1 |
| Marangos, PJ | 1 |
| Fenstermacher, MJ | 1 |
| Narayana, PA | 1 |
| Huang, QF | 1 |
| Barnes, DM | 1 |
| Bruhn, H | 1 |
| Frahm, J | 1 |
| Gyngell, ML | 1 |
| Merboldt, KD | 1 |
| Hänicke, W | 1 |
| Sauter, R | 1 |
| Savenko, SN | 1 |
| Vladkovskiĭ, IK | 1 |
| Maidanik, FE | 1 |
| Watanabe, S | 1 |
| Otsuki, S | 1 |
| Mitsunobu, K | 1 |
| Sannomiya, T | 1 |
| Okumura, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| MRI Biomarkers of Risk in Sedentary and Exercise Trained Humans[NCT02729428] | 71 participants (Actual) | Observational | 2016-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
35 other studies available for aspartic acid and Cerebrovascular Disorders
| Article | Year |
|---|---|
Metabolic changes in patients with aneurysmal subarachnoid hemorrhage apart from perfusion deficits: neuronal mitochondrial injury?
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Cerebrovascular Di | 2013 |
¹H-MRS before and after resuscitation following selective cerebral ultra-profound hypothermic blood flow occlusion in monkeys.
Topics: Animals; Aspartic Acid; Brain; Carotid Stenosis; Cerebrovascular Disorders; Choline; Circulatory Arr | 2015 |
Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease.
Topics: Aged; Aspartic Acid; Axons; Case-Control Studies; Cerebrovascular Disorders; Cognition; Female; Huma | 2009 |
Hippocampal volumes, proton magnetic resonance spectroscopy metabolites, and cerebrovascular disease in mild cognitive impairment subtypes.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cerebrovascular Disorders; Chi-Square | 2008 |
Risk of dementia in MCI: combined effect of cerebrovascular disease, volumetric MRI, and 1H MRS.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Atrophy; Biomarkers; Brain; Cerebrovascular Disorders; Cogni | 2009 |
Reduced thalamic N-acetylaspartate in idiopathic normal pressure hydrocephalus: a controlled 1H-magnetic resonance spectroscopy study of frontal deep white matter and the thalamus using absolute quantification.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Basal Ganglia; Cerebrovascular Disorders; Cognition; Female; | 2011 |
Diabetic brain damage in hypertension: role of renin-angiotensin system.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Aspartic Acid; Benzimidazoles; Biphenyl Compounds; Bl | 2005 |
Massive persistent release of excitatory amino acids following human occlusive stroke.
Topics: Aspartic Acid; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Disorders; Excitatory Ami | 1995 |
In vivo proton magnetic resonance spectroscopy for metabolic changes of human brain edema.
Topics: Adult; Aspartic Acid; Brain; Brain Edema; Cerebrovascular Disorders; Creatinine; Female; Humans; Lac | 1994 |
Cerebral metabolites in patients with acute and subacute strokes: concentrations determined by quantitative proton MR spectroscopy.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Cerebrovascular Dis | 1995 |
Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Cerebrovascular Disorders; Choline; Creatin | 1994 |
Proton magnetic resonance spectroscopy and gadolinium-DTPA perfusion imaging of asymptomatic MRI white matter lesions.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Diseases; Cerebrovascular Circulation; Cer | 1995 |
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr | 1994 |
Incorporating lactate/lipid discrimination into a spectroscopic imaging sequence.
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Cerebrovascular Disorders; Humans; Lactates; Lipids | 1993 |
Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Brain Ischemia; Cerebral Cortex | 1996 |
Reproducibility of metabolite peak areas in 1H MRS of brain.
Topics: Adult; Analysis of Variance; Artifacts; Aspartic Acid; Brain; Brain Neoplasms; Cerebrovascular Disor | 1996 |
Proton MR spectroscopy in acute middle cerebral artery stroke.
Topics: Acute Disease; Aged; Artifacts; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Cerebral Infarctio | 1996 |
Normalisation of metabolite images in 1H NMR spectroscopic imaging.
Topics: Algorithms; Artifacts; Aspartic Acid; Brain; Cerebrovascular Disorders; Choline; Creatine; Fourier A | 1997 |
Alcohol-induced vascular damage of brain is ameliorated by administration of magnesium.
Topics: Animals; Arterioles; Aspartic Acid; Barium Compounds; Brain; Carotid Arteries; Cells, Cultured; Cere | 1998 |
Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Edema; B | 1998 |
A common Glu298-->Asp (894G-->T) mutation at exon 7 of the endothelial nitric oxide synthase gene and vascular complications in type 2 diabetes.
Topics: Albuminuria; Amino Acid Substitution; Angina Pectoris; Aspartic Acid; Cerebrovascular Disorders; Dia | 1998 |
Neurone-specific enolase and N-acetyl-aspartate as potential peripheral markers of ischaemic stroke.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Disorders; Female; Hu | 1999 |
No association between Glu/Asp polymorphism of NOS3 gene and ischemic stroke.
Topics: Aged; Alleles; Aspartic Acid; Brain Ischemia; Cerebrovascular Disorders; Female; Genotype; Glutamic | 1999 |
Long-term cerebral metabolite changes on proton magnetic resonance spectroscopy in patients cured of acute lymphoblastic leukemia with previous intrathecal methotrexate and cranial irradiation prophylaxis.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Aspartic Acid; Brain; Brain Infarction; Cerebrov | 2001 |
Neuronal ischemic injury: light microscopy, ultrastructure and biochemistry.
Topics: Alanine; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Death; Cats; Cell Survival; Cerebrova | 1978 |
Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Aspartic Acid; Atrophy; Brain; Brain Ischemia; Cerebral Infa | 1992 |
Early time course of N-acetylaspartate, creatine and phosphocreatine, and compounds containing choline in the brain after acute stroke. A proton magnetic resonance spectroscopy study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Cerebrovascular Circu | 1992 |
Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients.
Topics: Aspartic Acid; Brain; Cerebrovascular Disorders; Humans; Lactates; Magnetic Resonance Spectroscopy; | 1992 |
Adenosinergic approaches to stroke therapeutics.
Topics: Adenosine; Aspartic Acid; Cerebrovascular Disorders; Glutamates; Glutamic Acid; Humans; Receptors, P | 1990 |
Serial proton magnetic resonance spectroscopy of ischemic brain injury in humans.
Topics: Aged; Aspartic Acid; Brain; Cerebrovascular Disorders; Choline; Creatine; Female; Humans; Magnetic R | 1990 |
Magnesium ions prevent phencyclidine-induced cerebrovasospasms and rupture of cerebral microvessels: direct in-vivo microcirculatory studies on the rat brain.
Topics: Animals; Aspartic Acid; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Ischemic Att | 1990 |
NMDA receptors trigger excitement.
Topics: Aspartic Acid; Brain; Brain Ischemia; Cell Survival; Cerebrovascular Disorders; Electrophysiology; G | 1988 |
Cerebral metabolism in man after acute stroke: new observations using localized proton NMR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; gamma-A | 1989 |
[The serum amino acid spectrum of hypertensive patients with cerebral circulatory disorders].
Topics: Adult; Aged; Alanine; Amino Acids; Arginine; Aspartic Acid; Cerebrovascular Disorders; Female; Human | 1971 |
[U-14C]glucose metabolism of the perfused cat brain with blood flow disturbances.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Blood Glucose; Brain; Carbon Isotopes; Cats; Cerebr | 1970 |