aspartic acid has been researched along with Cerebral Ischemia in 222 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (14.41) | 18.7374 |
| 1990's | 99 (44.59) | 18.2507 |
| 2000's | 67 (30.18) | 29.6817 |
| 2010's | 23 (10.36) | 24.3611 |
| 2020's | 1 (0.45) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Guo, D; He, J; Jia, Y; Peng, H; Shi, M; Sun, L; Wang, A; Wang, Y; Xu, Q; Xu, T; Yang, P; Zhang, Y; Zhong, C; Zhu, Z | 1 |
| Choi, CG; Choi, Y; Ha, HK; Ham, SJ; Jeon, SB; Jung, SC; Kim, J; Kim, JK; Kim, KW; Kim, ST; Kwon, JI; Shim, WH; Sung, YS; Woo, CW; Woo, DC | 1 |
| Cao, L; Cao, ZY; Hu, HF; Luo, YP; Wang, ZZ; Xiao, W; Zhang, H; Zhang, XZ | 1 |
| Adair, JC; Gasparovic, C; Huisa, B; Prestopnik, J; Rosenberg, GA; Schrader, R; Taheri, S; Thompson, J | 1 |
| Akatsu, H; Datta, A; Heese, K; Sze, SK | 1 |
| Lei, RY; Liu, YR; Lu, H; Wang, CE; Zhang, BA; Zhang, GB; Zhu, HC | 1 |
| Guan, YM; Huang, HL; Liu, B; Liu, XC; Wang, QS; Wang, ZW; Zhu, Y; Zhu, YZ | 1 |
| Bie, XD; Ge, LJ; Han, J; Wan, HT; Yang, JH; Zhang, YY | 1 |
| Dumez, JN; Frydman, L; Grant, SC; Rosenberg, JT; Shemesh, N | 1 |
| Huber, VJ; Ida, M; Igarashi, H; Nakada, T; Suzuki, Y | 1 |
| Aguilar-Sosa, E; Alvarado-Moreno, A; Esparza-García, JC; Guadalupe Valades-Mejía, M; Hernández-Juárez, J; Isordia-Salas, I; Leaños-Miranda, A; Majluf-Cruz, A; Santiago-Germán, D | 1 |
| Keep, RF; Lawrence, DA; Li, C; Su, EJ; Tang, Y; Xiang, J | 1 |
| Chen, K; Duan, F; Li, S; Liu, Y; Sun, W; Tian, P; Yan, Z; Yang, R; Zhao, Y | 1 |
| Armitage, PA; Bastin, ME; Chappell, FM; Cvoro, V; Marshall, I; Muñoz Maniega, S; Wardlaw, JM | 1 |
| Armitage, PA; Bastin, ME; Carpenter, TK; Cvoro, V; Dennis, MS; Farrall, AJ; Marshall, I; Rivers, CS; Wardlaw, JM; Wartolowska, K | 1 |
| Oja, SS; Saransaari, P | 2 |
| Armitage, PA; Bastin, ME; Carpenter, T; Cvoro, V; Dennis, MS; Marshall, I; Rivers, CS; Wardlaw, JM | 1 |
| Kim, KS; Kim, ST; Lee, BS; Woo, CW | 1 |
| Bar-Shir, A; Cohen, Y; Nossin-Manor, R; Shemesh, N | 1 |
| Lou, HY; Xu, SL; Zhang, JF; Zhang, L; Zhang, MM | 1 |
| Feng, W; Li, J; Li, SX; Wang, H; Yang, ZZ | 1 |
| Alf, MF; Berthet, C; Gruetter, R; Hirt, L; Lei, H; Mlynarik, V | 1 |
| Reismann, P | 1 |
| Mullins, ME | 1 |
| Fang, J; Liu, ZH; Wang, XY; Zhang, J; Zheng, DD | 1 |
| Igarashi, H | 1 |
| Shen, H; Shen, X; Wang, R; Wu, M | 1 |
| Hu, M; Jing, Z; Li, G; Li, T; Liu, J; Meng, F; Wang, Z; Xiong, L; Yu, Y; Zhang, X | 1 |
| Andrews, PJ; Easton, VJ; Macmillan, CS; Marshall, I; Wardlaw, JM; Wild, JM | 1 |
| Du, GY; Fu, JH | 1 |
| Alperin, N; Chu, Y; Emborg, ME; Khan, N; Kompoliti, K; Kordower, JH; Roitberg, B; Tuccar, E | 1 |
| Hainsworth, AH; Lambert, DG; Nelson, RM; Richard Green, A | 1 |
| Budd, SL; Gillessen, T; Lipton, SA | 1 |
| Zheng, S; Zuo, Z | 1 |
| Beley, A; Bertrand, N; Demougeot, C; Garnier, P; Giroud, M; Marie, C; Mossiat, C; Prigent-Tessier, A | 1 |
| Crawshaw, S; Moody, A; Rubin, PC; Rutherford, JM | 1 |
| Boretius, S; Frahm, J; Michaelis, T; Natt, O; Schwarcz, A; Watanabe, T | 1 |
| Li, YF; Peng, H; Sun, SG | 1 |
| Chen, W; Lei, H; Zhang, Y; Zhu, XH | 1 |
| Ali, Z; Baker, G; Guterman, LR; Hopkins, LN; Qureshi, AI; Shuaib, A; Suri, MF; Todd, K | 1 |
| Confort-Gouny, S; Cozzone, PJ; Denis, B; Lefur, Y; Nicoli, F; Ranjeva, JP | 1 |
| Blobner, M; Engelhard, K; Hoffman, WE; Kochs, E; Matthes, B; Werner, C | 1 |
| Chen, CY; Chin, SC; Chung, HW; Huang, IJ; Lee, CS; Liou, M; Liu, YJ | 1 |
| Fan, M; Li, LY; Liao, WJ; Liu, ML; Yang, WT; Yang, YH | 1 |
| Feustel, PJ; Jin, Y; Kimelberg, HK | 1 |
| Gröhn, OH; Kauppinen, RA; Kettunen, MI | 1 |
| Ben Salem, D; Brunotte, F; Giroud, M; Lalande, A; Walker, PM | 1 |
| Castagnetta, M; Cervetto, C; Marcoli, M; Maura, G; Sbaffi, P | 1 |
| Beley, A; Demougeot, C; Giroud, M; Marie, C | 1 |
| Bonfanti, A; Chiaramonte, G; Marcoli, M; Maura, G; Ongini, E; Raiteri, M; Roccatagliata, P | 1 |
| Gianfriddo, M; Melani, A; Pedata, F; Turchi, D | 1 |
| Hur, NW; Jee, SH; Kang, DR; Kim, HC; Nam, CM; Shim, JS; Suh, I | 1 |
| Jellish, WS; Kindel, G; Murdoch, J; White, FA; Zhang, X | 1 |
| Bhardwaj, A; Harukuni, I | 1 |
| Aygok, GA; Bullock, R; Fatouros, P; Marmarou, A; Signoretti, S | 1 |
| Had-Aissouni, L; Kerkerian-Le Goff, L; Melon, C; Nafia, I; Re, DB; Shimamoto, K | 1 |
| Molchanova, SM; Oja, SS; Saransaari, P | 1 |
| Ahmad, AS; Ahmad, M; Ansari, MA; Ishrat, T; Islam, F; Khan, MB; Saleem, S; Yousuf, S | 1 |
| Camacho, A; Massieu, L; Montiel, T | 1 |
| de Leon, MJ; Glodzik-Sobanska, L; Li, J; Mosconi, L; Slowik, A; Sobiecka, B; Szczudlik, A; Walecki, J | 1 |
| Atochin, DN; Ayata, C; Critchlow, JD; Dantas, AP; Huang, PL; Liu, VW; Looft-Wilson, R; Michel, T; Moskowitz, MA; Murata, T; Salomone, S; Sessa, WC; Shin, HK; Wang, A | 1 |
| Benner, T; Gonzalez, RG; Koroshetz, WJ; Lee, V; Ratai, E; Schaefer, PW; Singhal, AB; Sorensen, AG; Vangel, M | 1 |
| Barrick, TR; Charlton, RA; Howe, FA; Markus, HS; McIntyre, DJ; Nitkunan, A | 1 |
| Balázs, R; Bosley, TM; Gordon, RD; Woodhams, PL | 1 |
| Akopian, VP; Balian, LS | 1 |
| Erecińska, M; Hauptman, M; Nelson, D; Wilson, DF | 1 |
| Erecińska, M; Nelson, D; Silver, IA; Wilson, DF | 1 |
| Walker, JB; Woznicki, DT | 1 |
| Constans, JM; Fein, G; Gerson, J; MacKay, S; Meyerhoff, DJ; Norman, D; Weiner, MW | 1 |
| Boulu, RG; Callebert, J; Ghribi, O; Plotkine, M | 1 |
| Hsu, YI; Lai, ML; Ma, S; Yu, CY | 1 |
| Frahm, J; Nagatomo, Y; Prielmeier, F; Wick, M | 1 |
| Boulu, RG; Callebert, J; Ghribi, O; Plotkine, M; Verrecchia, C | 1 |
| Berg-Johnsen, J; Grøndahl, TO; Haugstad, TS; Hegstad, E; Langmoen, IA | 1 |
| Héron, A; Lasbennes, F; Seylaz, J; Springhetti, V | 1 |
| Domańska-Janik, K; Zabøocka, B | 1 |
| Charniga, C; Goderie, S; Kimelberg, HK; Rutledge, E | 1 |
| O'Regan, MH; Perkins, LM; Phillis, JW; Smith-Barbour, M | 3 |
| Berkelbach van der Sprenkel, JW; Nicolay, K; Tulleken, CA; van der Toorn, A; Verheul, HB | 1 |
| Conte, C; Federico, F; Ferrari, E; Giannini, P; Liguori, M; Picciola, E; Simone, IL; Tortorella, C | 1 |
| de Koster, A; Heerschap, A; Horstink, MW; Thijssen, HO; van 't Hof, MA; Zijlmans, JC | 1 |
| Berger, R; Djuricic, B; Paschen, W | 1 |
| Chen, J; Graham, SH; Swanson, RA | 1 |
| Blennow, M; Hagberg, H; Hamberger, A; Kjellmer, I; Lagercrantz, H; Sandberg, M; Thiringer, K; Thornberg, E | 1 |
| Blennow, M; Hagberg, H; Ingvar, M; Lagercrantz, H; Wang, YS; Zeman, J | 1 |
| Feuerstein, G; Gu, JL; Lysko, PG; Webb, CL; Yue, TL | 1 |
| Chou, YC; Lin, WJ; Sapolsky, RM | 1 |
| Abe, H; Hida, K; Houkin, K; Iwasaki, Y; Kamada, K; Matsuzawa, H; Nakada, T | 1 |
| Moonen, CT; van Zijl, PC | 1 |
| Fujimori, K; Miyake, K; Okada, M; Taguchi, T; Takagi, N; Takeo, S; Tanonaka, K | 1 |
| Bayne, L; Graham, SH; Meyerhoff, DJ; Sharp, FR; Weiner, MW | 1 |
| Felber, SR | 1 |
| Olney, JW | 1 |
| Bourgeois, D; Kozlowski, P | 1 |
| Kuo, JS; Lin, NN; Liu, L; Tsai, PJ; Yang, CS | 1 |
| Nakashima, K; Todd, MM | 2 |
| Constans, JM; Fein, G; MacKay, S; Meyerhoff, DJ; Norman, D; Weiner, MW | 1 |
| Castillo, J; Dávalos, A; Naveiro, J; Noya, M | 1 |
| Back, T; Busch, E; Gyngell, ML; Hoehn-Berlage, M; Hossmann, KA; Kohno, K; Schmitz, B | 1 |
| Bullock, R; Harms, JF; Tsuchida, E; Woodward, JJ | 1 |
| During, MJ; Gluckman, PD; Gunn, AJ; Gunning, MI; Mallard, CE; Tan, WK; Williams, CE | 1 |
| Barker, PB; Bryan, RN; Gillard, JH; Oppenheimer, SM; van Zijl, PC | 1 |
| Boris-Möller, F; Brandt, L; Nilsson, OG; Säveland, H; Wieloch, T | 1 |
| Fernandez, EJ; Higuchi, T; Maudsley, AA; Shimizu, H; Weiner, MW; Weinstein, PR | 1 |
| Chileuitt, L; Faden, AI; Sappey-Marinier, D; Weiner, MW; Weinstein, PR | 1 |
| Conte, C; d'Addabbo, A; Federico, F; Inchingolo, V; Lauriero, F; Rubini, G; Simone, I | 1 |
| Domańska-Janik, K; Zabłocka, B | 1 |
| O'Regan, MH; Phillis, JW | 1 |
| Dijkhuizen, RM; Nicolay, K; Tulleken, CA; van der Toorn, A | 1 |
| Boiadzhian, VG; Danielian, RK; Karagezian, KG; Manucharian, GG; Ordukhanian, AA; Sekoian, AE; Sekoian, ES | 1 |
| Fink-Jensen, A; Hansen, AJ; Sager, TN | 1 |
| Handa, Y; Kaneko, M; Kobayashi, H; Kubota, T; Matuda, T | 1 |
| Kahn, RA; Panah, M; Weinberger, J | 1 |
| Kahn, RA; Kiffel, S; Panah, M; Weinberger, J | 1 |
| Chang, LH; Litt, L; Shimizu, H; Weinstein, PR; Zarow, G | 1 |
| Fernandez, EJ; Gaspary, HL; Graham, SH; Higuchi, T; Maudsley, AA; Rooney, WD; Weiner, MW | 1 |
| O'Regan, MH; Phillis, JW; Song, D | 1 |
| Furuya, S; Maeda, T; Morishita, H; Naruse, S | 1 |
| Amess, P; Cady, EB; Penrice, J; Sams, V; Wyatt, JS; Wylezinska, M | 1 |
| Harada, M; Miyoshi, H; Nishitani, H; Ootsuka, H; Tanouchi, M; Taoka, Y | 1 |
| Brooks, WM; Friedman, SD; Griffey, RR; Haseler, LJ; Sibbitt, WL | 1 |
| Das, K; Dhanuka, AK; Gupta, RK; Roy, R; Sengar, AR | 1 |
| Cheng, J; Zhao, P | 1 |
| Nicholls, DG; Pocock, JM | 1 |
| Barrier, L; Chalon, S; Guerraoui, A; Guilloteau, D; Huguet, F; Tallineau, C | 1 |
| Frahm, J; Fujimori, H; Michaelis, T; Wick, M | 1 |
| Chou, YC | 1 |
| Hayakawa, T; Kohmura, E; Nonaka, M; Wakayama, A; Yamashita, T; Yoshimine, T | 1 |
| Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Cannon, J; Dennis, MS; Lewis, SC; Marshall, I; Wardlaw, JM; Wild, J | 1 |
| Fujishima, M; Goda, H; Ibayashi, S; Nakane, H; Ooboshi, H; Sadoshima, S | 1 |
| Hu, S; Li, J; Yang, Q | 1 |
| Kozlowski, P; Malisza, KL; Peeling, J | 1 |
| Lei, H; Peeling, J | 1 |
| Feustel, PJ; Keller, RW; Kimelberg, HK; Seki, Y; Tranmer, BI | 1 |
| Fink-Jensen, A; Hansen, AJ; Hedehus, M; Laursen, H; Rosenbaum, S; Sager, TN; Stensgaard, A; Topp, S; Valsborg, JS | 1 |
| Alekseev, AA; Gusev, EI; Kovalenko, AV; Kudrin, VS; Malikova, LA; Raevskiĭ, KS; Skvortsova, VI; Sokolov, MA | 1 |
| Cunningham, RT; de Jager, AE; Jakobs, C; Korf, J; Stevens, H | 1 |
| Bascaramurty, S; Kozlowski, P; Malisza, KL; Ning, G; Tuor, UI | 1 |
| Cumming, A; Dahiyat, MT; MacLeod, MJ; Meiklejohn, D; Shaw, D; St Clair, D | 1 |
| Hayakawa, T; Kohmura, E; Kumura, E; Nonaka, M; Wakayama, A; Yoshimine, T | 1 |
| Blamire, AM; Flitney, D; Matthews, PM; Pendlebury, ST; Pineiro, R; Smith, S; Styles, P | 1 |
| Gomi, S; Greenberg, JH; Karp, A | 1 |
| Diaz, FG; Guyot, LL; O'Regan, MH; Phillis, JW; Song, D | 2 |
| Cha, S; George, AE | 1 |
| Amend, DL; Capizzano, AA; Chui, HC; Fein, G; Jagust, W; Maudsley, AA; Norman, D; Schuff, N; Segal, MR; Tanabe, JL; Weiner, MW | 1 |
| Gähwiler, BH; Gerber, U; Jabaudon, D; Scanziani, M | 1 |
| O'Regan, MH; Phillis, JW; Ren, J | 1 |
| Akar, E; Akar, N; Deda, G; Sipahi, T | 1 |
| Favalli, L; Govoni, S; Lanza, E; Masoero, E; Montalbetti, L; Rizzo, V; Rozza, A | 1 |
| Fujishima, M; Ibayashi, S; Kondo, A; Ooboshi, H; Sadoshima, S; Takano, K; Uchimura, H | 1 |
| Algra, A; Kappelle, LJ; Klijn, CJ; Tulleken, CA; van der Grond, J; van Gijn, J | 1 |
| Marshall, I; Wardlaw, JM; Warlow, CP; Wild, JM | 1 |
| Fahrig, T; Horváth, E; Jork, R; Mauler, F | 1 |
| Adelson, PD; Bell, MJ; Clark, RS; Graham, SH; Kochanek, PM; Marion, DW; Rose, ME; Ruppel, RA; Wisniewski, SR | 1 |
| Favalli, L; Frattini, P; Govoni, S; Masoero, E; Rozza, A; Scelsi, R | 1 |
| Dawson, LA; Djali, S; Gonzales, C; Vinegra, MA; Zaleska, MM | 1 |
| Kohsaka, S; Kudo, Y; Mishina, M; Nakajima-Iijima, S; Nakamura, K; Nakamura, T; Uchino, S | 1 |
| Bito, Y; Ebisu, T; Hirata, S; Mineura, K; Naruse, S; Takegami, T; Tanaka, C; Yamamoto, Y | 1 |
| Beley, A; Bertrand, N; Demougeot, C; Garnier, P; Giroud, M; Marie, C; Mossiat, C | 1 |
| Cho, YP; Kim, GE; Kim, ST; Lee, JH | 1 |
| Igarashi, H; Katayama, Y; Kwee, IL; Nakada, T; Terashi, A | 1 |
| Choe, BY; Choi, BG; Kang, JK; Kim, EN; Kim, MC; Lee, KS; Park, CK; Son, BC | 1 |
| Harada, M; Nagahiro, S; Uno, M | 1 |
| Bains, S; Connelly, K; McLaughlin, DP; Michael-Titus, AT; Stamford, JA; Toner, CC; Whelpton, R | 1 |
| Li, JY; Matsumoto, M; Nakano, M; Ueda, H; Yanagihara, T | 1 |
| Bruhn, T; Christensen, T; Diemer, NH | 1 |
| Harada, M; Hisaoka, S; Hong, F; Matsuda, T; Nishitani, H; Uno, M | 1 |
| Bogdan, AR; Gusnard, DA; Leigh, JS; Ohene-Frempong, K; Wang, Z; Zimmerman, RA | 1 |
| O'Regan, MH; Perkins, LM; Phillis, JW; Simpson, RE | 1 |
| Fernandez, EJ; Higuchi, T; Maudsley, AA; Weiner, MW | 1 |
| Grabb, MC; Roche, FM; Sciotti, VM; Van Wylen, DG | 1 |
| Boulu, RG; Callebert, J; Lekieffre, D; Plotkine, M | 1 |
| Boulu, RG; Buisson, A; Callebert, J; Mathieu, E; Plotkine, M | 1 |
| Berkelbach van der Sprenkel, JW; den Hollander, JA; Knufman, NM; Luyten, PR; Tulleken, CA; van Rijen, PC | 1 |
| Gideon, P; Henriksen, O | 1 |
| Calabrese, G; Deicken, R; Fein, G; Fisher, SN; Hetherington, HP; Sappey-Marinier, D; Van Dyke, C; Weiner, MW | 1 |
| Abiko, H; Faden, AI; James, TL; Weinstein, PR; Widmer, H | 1 |
| Chiba, K; Kuwahara, O; Mitsumoto, Y; Mohri, T | 1 |
| Bullock, R; Butcher, SP; Chen, MH; Kendall, L; McCulloch, J | 1 |
| Phillis, JW; Simpson, RE; Walter, GA | 1 |
| Alesiani, M; Cherici, G; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Hertz, L; Juurlink, BH; Peng, LA | 1 |
| Lazdunski, M; Schaeffer, P | 1 |
| Bommarito, M; Johnston, MV; McDonald, JW; Silverstein, FS | 1 |
| Alesiani, M; Carla, V; Cherici, G; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Albers, GW | 1 |
| Kanazawa, I; Nakayama, H; Sano, K; Tamura, A | 1 |
| Hansen, AJ; Honoré, T; Jacobsen, P; Nielsen, EO; Sheardown, MJ | 1 |
| Meldrum, BS; Swan, JH | 1 |
| Barnes, DM | 1 |
| Bengtsson, F; Siesjö, BK | 1 |
| Bruhn, H; Frahm, J; Gyngell, ML; Hänicke, W; Merboldt, KD; Sauter, R | 1 |
| Choi, DW; Collins, RC; Dobkin, BH | 1 |
| Borosky, S; Ellenberger, SR; Ferkany, JW; Guzewska, ME; Jones, SM; Kyle, DJ; Rzeszotarski, WJ; Sacaan, AI; Snell, LD; Willets, J | 1 |
| Araki, T; Kogure, K; Onodera, H | 1 |
| Albers, GW; Choi, DW; Goldberg, MP | 1 |
| Ikonomidou, C; Labruyere, J; Mosinger, JL; Olney, JW; Salles, KS | 1 |
| McCulloch, J; Nehls, DG; Park, CK; Teasdale, GM | 1 |
| Alger, JR; Brunetti, A; Hossmann, KA; Nagashima, G | 1 |
| Arbilla, S; Benavides, J; Carter, C; Legendre, P; Lloyd, KG; MacKenzie, ET; Noel, F; Thuret, F; Vincent, JD; Zivkovic, B | 1 |
| Bertin, J; Carter, C; Dupont, R; Duverger, D; Frost, J; Gaudilliere, B; Gotti, B; MacKenzie, ET; Rousseau, J; Scatton, B | 1 |
| Meldrum, B | 1 |
| Meldrum, B; Schwarcz, R | 1 |
| Engelsen, BA; Fonnum, F; Fosse, VM; Myrseth, E | 1 |
| Wieloch, T | 2 |
| Cheng, J; Simon, RP; Stout, S; Young, RS | 1 |
| Nakayama, H | 1 |
| Andersson, P; Hagberg, H; Kjellmer, I; Thiringer, K; Thordstein, M | 1 |
| Graham, DI; McCulloch, J; Nehls, DG; Park, CK; Teasdale, GM | 1 |
| Arcavi, LJ; Ferriero, DM; McIntosh, TK; Sagar, SM; Simon, RP | 1 |
| Valli, M | 1 |
| Bowery, NG; Hudson, AL; Wong, EH | 1 |
| Kunis, D; Saleh, J; Steinberg, GK | 1 |
| Allen, K; Crockard, HA; Frackowiak, RS; Gadian, DG; Proctor, E; Russell, RW; Williams, SR | 1 |
| Hagberg, H; Hamberger, A; Jacobson, I; Lehmann, A; Nyström, B; Sandberg, M | 1 |
15 review(s) available for aspartic acid and Cerebral Ischemia
| Article | Year |
|---|---|
N-acetylaspartate decrease in acute stage of ischemic stroke: a perspective from experimental and clinical studies.
Topics: Acute Disease; Animals; Aspartic Acid; Brain; Brain Ischemia; Humans; Magnetic Resonance Spectroscopy; Rats; Stroke | 2015 |
Mechanisms Underlying Astrocyte Endfeet Swelling in Stroke.
Topics: Animals; Aspartic Acid; Astrocytes; Blood-Brain Barrier; Brain Ischemia; Cell Size; Edema; Glutamic Acid; Humans; Potassium; Stroke | 2016 |
Excitatory amino acid neurotoxicity.
Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Calcium; Epilepsy; Glutamic Acid; Humans; Mitochondria; Nervous System Diseases; Neurodegenerative Diseases; Reactive Nitrogen Species; Reactive Oxygen Species; Receptors, Glutamate; Signal Transduction | 2002 |
N-acetylaspartate: a literature review of animal research on brain ischaemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Chromatography, High Pressure Liquid; Disease Models, Animal; Disease Progression; Magnetic Resonance Spectroscopy; Neurons | 2004 |
The protective effect of adenosine A2A receptor antagonism in cerebral ischemia.
Topics: Adenosine A2 Receptor Antagonists; Animals; Aspartic Acid; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Hypoxia, Brain; Neuroprotective Agents; Receptor, Adenosine A2A; Time Factors | 2005 |
Mechanisms of brain injury after global cerebral ischemia.
Topics: Apoptosis; Aspartic Acid; Body Temperature; Brain; Brain Ischemia; Calcium Channels; Cytokines; Dopamine; Extracellular Space; Homocysteine; Humans; Necrosis; Neurons; Nitric Oxide; Norepinephrine; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2006 |
Neurochemical and biophysical assessment of neonatal hypoxic-ischemic encephalopathy.
Topics: Animals; Aspartic Acid; Asphyxia Neonatorum; Brain; Brain Diseases; Brain Ischemia; Electrophysiology; Glutamates; Glutamic Acid; Humans; Infant, Newborn; Norepinephrine; Purines | 1994 |
Role of excitotoxins in developmental neuropathology.
Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain Diseases; Brain Ischemia; Cloning, Molecular; Cysteine; Glutamates; Glycine; Humans; Oxidoreductases Acting on Sulfur Group Donors; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
A review of in vivo 1H magnetic resonance spectroscopy of cerebral ischemia in rats.
Topics: Animals; Animals, Newborn; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Choline; Dichloroacetic Acid; Energy Metabolism; Hypothermia, Induced; Hypoxia, Brain; Lactates; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Prognosis; Protons; Rats; Reperfusion Injury | 1998 |
Potential therapeutic uses of N-methyl-D-aspartate antagonists in cerebral ischemia.
Topics: Aspartic Acid; Brain Ischemia; Glutamates; Glutamic Acid; Humans; Models, Biological; N-Methylaspartate; Nervous System; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis.
Topics: Aspartic Acid; Biological Transport, Active; Brain; Brain Ischemia; Calcium; Calcium Channels; Cell Membrane; Cell Survival; Glutamates; Homeostasis; Humans; Hypoglycemia; N-Methylaspartate; Neurons; Potassium; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Selective vulnerability of the brain: new insights into the pathophysiology of stroke.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Cell Survival; Glutamates; Humans; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission | 1989 |
N-methyl-D-aspartate antagonists: ready for clinical trial in brain ischemia?
Topics: Aspartic Acid; Brain; Brain Ischemia; Clinical Trials as Topic; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Models, Neurological; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1989 |
Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters.
Topics: Alzheimer Disease; Animals; Aspartic Acid; Basal Ganglia Diseases; Brain; Brain Ischemia; Epilepsy; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Huntington Disease; Mice; Movement Disorders; Nerve Degeneration; Neurotransmitter Agents; Parkinson Disease; Rats | 1985 |
Neurochemical correlates to selective neuronal vulnerability.
Topics: Adenosine; Afferent Pathways; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Calcium; Chlorides; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypoglycemia; Models, Biological; Neural Inhibition; Neurochemistry; Neurons; Neurotransmitter Agents; Norepinephrine; Parasympathomimetics; Quinolinic Acid; Quinolinic Acids; Rats | 1985 |
5 trial(s) available for aspartic acid and Cerebral Ischemia
| Article | Year |
|---|---|
Plasma Amino Acid Neurotransmitters and Ischemic Stroke Prognosis: A Multicenter Prospective Study.
Topics: Aspartic Acid; Biomarkers; Brain Ischemia; Cohort Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Ischemic Stroke; Prognosis; Prospective Studies; Risk Factors; Stroke | 2023 |
Metabolic counterpart of decreased apparent diffusion coefficient during hyperacute ischemic stroke: a brain proton magnetic resonance spectroscopic imaging study.
Topics: Acute Disease; Adult; Aged; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; Diffusion; Diffusion Magnetic Resonance Imaging; Disease Progression; Female; Gadolinium; Humans; Lactic Acid; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Protons; Stroke; Time Factors | 2003 |
Mitochondrial injury measured by proton magnetic resonance spectroscopy in severe head trauma patients.
Topics: Adult; Aspartic Acid; Biomarkers; Brain; Brain Ischemia; Choline; Craniocerebral Trauma; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mitochondria; Mitochondrial Diseases; Prognosis; Protons; Trauma Severity Indices | 2005 |
Magnetic resonance spectroscopy study of oxygen therapy in ischemic stroke.
Topics: Acute Disease; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Ischemia; Diffusion Magnetic Resonance Imaging; Energy Metabolism; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Middle Aged; Oxygen Inhalation Therapy; Stroke | 2007 |
N-methyl-D-aspartate antagonists: ready for clinical trial in brain ischemia?
Topics: Aspartic Acid; Brain; Brain Ischemia; Clinical Trials as Topic; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Models, Neurological; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1989 |
203 other study(ies) available for aspartic acid and Cerebral Ischemia
| Article | Year |
|---|---|
The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model.
Topics: Animals; Apoptosis; Aspartic Acid; Brain Ischemia; Disease Models, Animal; Glutamic Acid; Humans; Hydrogen Sulfide; Neuroprotective Agents; Rats; Reperfusion Injury; Stroke; Taurine | 2017 |
[Protective effects of Ginkgo Terpene Lactones Meglumine Injection on focal cerebral ischemia in rats].
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Creatine Kinase, BB Form; Ginkgo biloba; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Lactic Acid; Lactones; Male; Malondialdehyde; Meglumine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Terpenes | 2017 |
1H-MR spectroscopy metabolite levels correlate with executive function in vascular cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Biomarkers; Brain Ischemia; Choline; Cognition Disorders; Creatine; Data Interpretation, Statistical; Dementia, Vascular; Executive Function; Female; Humans; Leukoaraiosis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Middle Aged; Neuropsychological Tests; Regression Analysis | 2013 |
Quantitative clinical proteomic study of autopsied human infarcted brain specimens to elucidate the deregulated pathways in ischemic stroke pathology.
Topics: Aspartic Acid; Autopsy; Biomarkers; Brain; Brain Infarction; Brain Ischemia; Cluster Analysis; Cytosol; Female; Ferritins; Gliosis; Humans; Iron; Malates; Mitochondria; Neurons; Oxygen; Proteome; Proteomics; Static Electricity; Trypsin | 2013 |
Effects of catalpol on ATPase and amino acids in gerbils with cerebral ischemia/reperfusion injury.
Topics: Adenosine Triphosphatases; Animals; Aspartic Acid; Brain Chemistry; Brain Ischemia; Carotid Artery, Common; Cell Membrane; Constriction; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gerbillinae; Glutamic Acid; Iridoid Glucosides; Male; Models, Animal; Molecular Structure; Nerve Tissue Proteins; Neuroprotective Agents; Premedication; Reperfusion Injury; Single-Blind Method | 2014 |
Effect of human umbilical cord blood mesenchymal stem cell transplantation on neuronal metabolites in ischemic rabbits.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Cord Blood Stem Cell Transplantation; Creatine; Lactic Acid; Male; Neurons; Rabbits | 2014 |
Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Glutamic Acid; Infarction, Middle Cerebral Artery; Male; Microdialysis; Molecular Structure; Neurotransmitter Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Taurine; Time Factors | 2014 |
Metabolic T1 dynamics and longitudinal relaxation enhancement in vivo at ultrahigh magnetic fields on ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Angiography; Cerebrovascular Circulation; Choline; Creatine; Female; Lactic Acid; Magnetic Resonance Angiography; Male; Rats; Rats, Sprague-Dawley; Stroke | 2014 |
GLU298ASP and 4G/5G Polymorphisms and the Risk of Ischemic Stroke in Young Individuals.
Topics: Adult; Aspartic Acid; Brain Ischemia; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Male; Mexico; Nitric Oxide Synthase Type III; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Stroke | 2015 |
Analysis of Potential Amino Acid Biomarkers in Brain Tissue and the Effect of Galangin on Cerebral Ischemia.
Topics: Alanine; Amino Acid Transport Systems, Neutral; Animals; Aspartic Acid; Biomarkers; Brain; Brain Ischemia; Excitatory Amino Acid Transporter 3; Flavonoids; Free Radical Scavengers; Glutamate Dehydrogenase; Glutamic Acid; Humans; Protein Interaction Maps; Rats; Transferases (Other Substituted Phosphate Groups) | 2016 |
Changes in NAA and lactate following ischemic stroke: a serial MR spectroscopic imaging study.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain; Brain Ischemia; Brain Mapping; Cell Death; Diffusion Magnetic Resonance Imaging; Disease Progression; Down-Regulation; Energy Metabolism; Female; Humans; Lactic Acid; Linear Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Stroke; Time Factors | 2008 |
Associations between diffusion and perfusion parameters, N-acetyl aspartate, and lactate in acute ischemic stroke.
Topics: Acute Disease; Aspartic Acid; Brain Ischemia; Cell Death; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Humans; Image Processing, Computer-Assisted; Lactic Acid; Linear Models; Prospective Studies; Stroke | 2009 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine | 2009 |
MR diffusion and perfusion parameters: relationship to metabolites in acute ischaemic stroke.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Female; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prospective Studies; Severity of Illness Index | 2010 |
Correlation between lactate and neuronal cell damage in the rat brain after focal ischemia: An in vivo 1H magnetic resonance spectroscopic (1H-MRS) study.
Topics: Analysis of Variance; Animals; Apoptosis; Aspartic Acid; Biomarkers; Brain; Brain Ischemia; Creatinine; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Follow-Up Studies; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Lactic Acid; Lipid Metabolism; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley | 2010 |
Late stimulation of the sphenopalatine-ganglion in ischemic rats: improvement in N-acetyl-aspartate levels and diffusion weighted imaging characteristics as seen by MR.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Diffusion Magnetic Resonance Imaging; Electric Stimulation Therapy; Electrodes; Ganglia; Infarction, Middle Cerebral Artery; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Time Factors | 2010 |
[Experimental study of hippocampal neuronic lesion in ischemic rat by magnetic resonance spectroscopy].
Topics: Animals; Aspartic Acid; Brain Ischemia; Female; Hippocampus; Magnetic Resonance Spectroscopy; Male; Neurons; Rats; Rats, Wistar | 2007 |
Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Ginkgo biloba; Ginkgolides; Glutamic Acid; Glycine; Infarction, Middle Cerebral Artery; Lactones; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2011 |
High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice.
Topics: Animals; Aspartic Acid; Brain Ischemia; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Models, Biological; Neostriatum; Neurochemistry; Taurine; Time Factors | 2012 |
[Study of the Toll-like receptor 4 gene polymorphisms in diseases presenting with subclinical and chronic inflammation].
Topics: Alleles; Aspartic Acid; Brain Ischemia; Chronic Disease; Cytokines; Diabetes Complications; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Glycine; Humans; Inflammation; Isoleucine; Periodontitis; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Stroke; Threonine; Toll-Like Receptor 4 | 2011 |
Daydreaming about our metaphorical tool belt.
Topics: Aging; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Female; Humans; Male | 2012 |
The effect of age and cerebral ischemia on diffusion-weighted proton MR spectroscopy of the human brain.
Topics: Adult; Aging; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Female; Humans; Male; Reproducibility of Results; Sensitivity and Specificity | 2012 |
[Proton magnetic resonance spectroscopy as a time clock measurement device in cerebral ischemia].
Topics: Animals; Aspartic Acid; Biomarkers; Brain Ischemia; Magnetic Resonance Spectroscopy; Time Factors | 2011 |
[Effects of theanine on cerebral ischemia-reperfusion injury in rats].
Topics: Animals; Aspartic Acid; Brain Ischemia; Brain-Derived Neurotrophic Factor; Glutamates; Male; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger | 2011 |
Association between Glu298Asp/677C-T single nucleotide polymorphism in the eNOS/MTHRF gene and blood stasis syndrome of ischemic stroke.
Topics: Aged; Aspartic Acid; Base Sequence; Brain Ischemia; DNA Primers; Female; Glutamic Acid; Hemostasis; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Stroke | 2012 |
Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Child; Choline; Creatine; Critical Care; Diffuse Axonal Injury; Energy Metabolism; Female; Follow-Up Studies; Glasgow Coma Scale; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Subarachnoid Hemorrhage; Tomography, X-Ray Computed | 2002 |
[Effect of tianma cuzhi keli (TMCZKL) on contents of transmitter amino acids of brain tissue in the mouse repetitious cerebral ischemia reperfusion].
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Drug Combinations; Drugs, Chinese Herbal; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Mice; Neuroprotective Agents; Orchidaceae; Plants, Medicinal; Random Allocation; Reperfusion Injury; Rubiaceae | 2001 |
Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Chronic Disease; Follow-Up Studies; Immunohistochemistry; Infarction, Middle Cerebral Artery; Macaca fascicularis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Models, Animal; Motor Skills; Radiography | 2003 |
Pharmacology of ischemia-induced glutamate efflux from rat cerebral cortex in vitro.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Brain Ischemia; Calcium Channel Blockers; Calcium Signaling; Cerebral Cortex; Chelating Agents; Chloride Channels; Female; Glutamic Acid; Ion Channels; Lanthanum; Magnesium; Neurons; Rats; Rats, Wistar; Sodium Channel Blockers | 2003 |
Isoflurane preconditioning reduces purkinje cell death in an in vitro model of rat cerebellar ischemia.
Topics: Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; Cell Death; Cell Survival; Cerebellar Diseases; Disease Models, Animal; Glyburide; Ischemic Preconditioning; Isoflurane; Male; Nerve Degeneration; Organ Culture Techniques; Organophosphonates; Potassium Channel Blockers; Purkinje Cells; Rats; Rats, Sprague-Dawley | 2003 |
Reversible loss of N-acetyl-aspartate in rats subjected to long-term focal cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Chromatography, High Pressure Liquid; Chronic Disease; Male; Neuroglia; Neurons; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Stroke | 2003 |
Magnetic resonance spectroscopy in pre-eclampsia: evidence of cerebral ischaemia.
Topics: Adolescent; Adult; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Constriction, Pathologic; Female; Humans; Magnetic Resonance Angiography; Magnetic Resonance Spectroscopy; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Prospective Studies | 2003 |
Localized proton MRS of cerebral metabolite profiles in different mouse strains.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protons | 2003 |
Effects of Ginkgo biloba extract on acute cerebral ischemia in rats analyzed by magnetic resonance spectroscopy.
Topics: Animals; Aspartic Acid; Brain Ischemia; Choline; Creatine; Drugs, Chinese Herbal; Ginkgo biloba; Hippocampus; Lactates; Magnetic Resonance Spectroscopy; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley | 2003 |
Changes in the proton T2 relaxation times of cerebral water and metabolites during forebrain ischemia in rat at 9.4 T.
Topics: Animals; Aspartic Acid; Brain Ischemia; Creatine; Linear Models; Magnetic Resonance Spectroscopy; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Water | 2003 |
Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study.
Topics: Analysis of Variance; Animals; Asparagine; Aspartic Acid; Brain Ischemia; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Disease Models, Animal; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Microdialysis; Prospective Studies; Rabbits; Single-Blind Method; Stroke; Taurine; Time Factors | 2003 |
The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Ischemia; Catecholamines; Chromatography, High Pressure Liquid; Electroencephalography; Epinephrine; Glutamic Acid; Hypotension; Male; Methyl Ethers; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Propofol; Rats; Rats, Sprague-Dawley; Reperfusion; Sevoflurane | 2003 |
Neuronal damage after ischemic injury in the middle cerebral arterial territory: deep watershed versus territorial infarction at MR perfusion and spectroscopic imaging.
Topics: Aspartic Acid; Blood Volume; Brain; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Contrast Media; Diagnosis, Differential; Disease Progression; Female; Humans; Infarction, Middle Cerebral Artery; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Time Factors | 2003 |
[The effects of Erigeron breviscapus preparation on the imaging and neuronal metabolites at the early time points after reperfusion following the ischemic cerebral injury in rats].
Topics: Animals; Aspartic Acid; Asteraceae; Brain; Brain Ischemia; Choline; Creatine; Drugs, Chinese Herbal; Infarction, Middle Cerebral Artery; Injections; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2003 |
Volume-regulated anion channels are the predominant contributors to release of excitatory amino acids in the ischemic cortical penumbra.
Topics: Amino Acid Transport System X-AG; Animals; Anion Transport Proteins; Aspartic Acid; Astrocytes; Brain Ischemia; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Infarction, Middle Cerebral Artery; Kainic Acid; Microdialysis; Neurons; Rats; Receptors, Glutamate; Tamoxifen; Taurine | 2004 |
Quantitative T1rho NMR spectroscopy of rat cerebral metabolites in vivo: effects of global ischemia.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatinine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Water | 2004 |
Time course of NAA T2 and ADC(w) in ischaemic stroke patients: 1H MRS imaging and diffusion-weighted MRI.
Topics: Aged; Analysis of Variance; Aspartic Acid; Brain Ischemia; Brain Mapping; Diffusion Magnetic Resonance Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Sensitivity and Specificity; Stroke; Tritium | 2004 |
5-HT control of ischemia-evoked glutamate efflux from human cerebrocortical slices.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glucose; Glutamic Acid; Humans; Hypoxia, Brain; In Vitro Techniques; Male; Middle Aged; Reperfusion Injury; Serotonin; Serotonin Receptor Agonists | 2004 |
Glutamate efflux from human cerebrocortical slices during ischemia: vesicular-like mode of glutamate release and sensitivity to A(2A) adenosine receptor blockade.
Topics: Adenosine A2 Receptor Antagonists; Adult; Aged; Anesthetics, Local; Aspartic Acid; Brain Ischemia; Calcium; Cerebral Cortex; Female; Glucose; Glutamic Acid; Humans; In Vitro Techniques; Male; Middle Aged; Neuroprotective Agents; Pyrimidines; Reperfusion Injury; Synaptic Vesicles; Tetrodotoxin; Triazoles | 2004 |
Elevated serum aminotransferase level as a predictor of intracerebral hemorrhage: Korea medical insurance corporation study.
Topics: Adult; Alanine Transaminase; Aspartic Acid; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Female; Follow-Up Studies; Glucose; Humans; Korea; Male; Middle Aged; Obesity; Proportional Hazards Models; Risk; Risk Factors; Stroke; Subarachnoid Hemorrhage; Time Factors; Transaminases | 2005 |
The effect of clonidine on cell survival, glutamate, and aspartate release in normo- and hyperglycemic rats after near complete forebrain ischemia.
Topics: Adrenergic alpha-Agonists; Animals; Aspartic Acid; Blood Glucose; Blood Pressure; Brain Chemistry; Brain Ischemia; Cell Death; Cell Survival; Chromatography, High Pressure Liquid; Clonidine; Glutamic Acid; Heart Rate; Hyperglycemia; Lactic Acid; Male; Nerve Degeneration; Prosencephalon; Rats; Rats, Sprague-Dawley; Visual Fields | 2005 |
Glutamate leakage from a compartmentalized intracellular metabolic pool and activation of the lipoxygenase pathway mediate oxidative astrocyte death by reversed glutamate transport.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; Brain; Brain Ischemia; Cell Compartmentation; Cell Death; Cells, Cultured; Cytoprotection; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Transporter 1; Extracellular Fluid; Glutamic Acid; Intracellular Fluid; Lipoxygenase; Mice; Oxidative Stress; Rats | 2006 |
Taurine attenuates D-[3H]aspartate release evoked by depolarization in ischemic corticostriatal slices.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Female; Furocoumarins; Glucose; Hypoxia; In Vitro Techniques; Male; Mice; Neuroprotective Agents; Stimulation, Chemical; Taurine; Tritium; Veratridine | 2006 |
Effect of Saffron (Crocus sativus) on neurobehavioral and neurochemical changes in cerebral ischemia in rats.
Topics: Animals; Antioxidants; Aspartic Acid; Behavior; Brain; Brain Chemistry; Brain Ischemia; Catalase; Crocus; Disease Models, Animal; Flowers; Glutamic Acid; Glutathione; Hand Strength; Lipid Peroxidation; Male; Malondialdehyde; Motor Activity; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase | 2006 |
The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cell Death; Energy Metabolism; Excitatory Amino Acids; Exocytosis; Extracellular Fluid; Glycolysis; Hippocampus; Male; Microdialysis; Nerve Degeneration; Nitrobenzoates; Phloretin; Rats; Rats, Wistar; Riluzole; Stilbenes; Tamoxifen; Vesicular Glutamate Transport Proteins; Voltage-Dependent Anion Channels | 2006 |
Prefrontal N-acetylaspartate and poststroke recovery: a longitudinal proton spectroscopy study.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Creatine; Female; Follow-Up Studies; Functional Laterality; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Protons; Recovery of Function; Stroke | 2007 |
The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.
Topics: Alanine; Animals; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Transgenic; Mutation; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Regional Blood Flow; Serine; Stroke | 2007 |
Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease.
Topics: Aged; Aspartic Acid; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebrovascular Circulation; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Female; Humans; Hypertension; Image Processing, Computer-Assisted; Inositol; Leukoaraiosis; Magnetic Resonance Spectroscopy; Male | 2008 |
Effects of anoxia on the stimulated release of amino acid neurotransmitters in the cerebellum in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Cerebellum; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hypoxia; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin | 1983 |
[Motor activity and the content of neuroactive amino acids in brain tissues].
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Cats; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hypothalamus; Male; Physical Exertion; Rats | 1983 |
Neurotransmitter amino acids in the CNS. II. Some changes in amino acid levels in rat brain synaptosomes during and after in vitro anoxia and simulated ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Culture Techniques; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Hypoxia, Brain; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptosomes; Tetrodotoxin; Veratridine | 1984 |
Neurotransmitter amino acids in the CNS. I. Regional changes in amino acid levels in rat brain during ischemia and reperfusion.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Taurine | 1984 |
Utilization of cyclocreatine phosphate, and analogue of creatine phosphate, by mouse brain during ischemia and its sparing action on brain energy reserves.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain; Brain Ischemia; Creatine; Energy Metabolism; Glutamates; Mice; Phosphocreatine | 1980 |
H-1 MR spectroscopic imaging of white matter signal hyperintensities: Alzheimer disease and ischemic vascular dementia.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Brain Diseases; Brain Ischemia; Case-Control Studies; Cerebral Ventricles; Choline; Creatine; Dementia; Dementia, Vascular; Female; Humans; Hydrogen; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurologic Examination | 1995 |
L-NAME modulates glutamate accumulation induced by K(+)-depolarization but not by forebrain ischaemia in the rat striatum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aspartic Acid; Brain Ischemia; Glutamic Acid; Male; Microdialysis; Neostriatum; Neuromuscular Depolarizing Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium; Rats; Rats, Wistar | 1994 |
Magnetic resonance spectroscopic findings in patients with subcortical ischemic stroke.
Topics: Adult; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Choline; Female; Humans; Lactates; Magnetic Resonance Spectroscopy; Male; Middle Aged | 1995 |
Alteration of intracellular metabolite diffusion in rat brain in vivo during ischemia and reperfusion.
Topics: Animals; Aspartic Acid; Body Water; Brain; Brain Ischemia; Choline; Creatine; Diffusion; Inositol; Intracellular Fluid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuroglia; Neurons; Prosencephalon; Rats; Rats, Wistar; Reperfusion; Time Factors | 1995 |
Blockers of NMDA-operated channels decrease glutamate and aspartate extracellular accumulation in striatum during forebrain ischaemia in rats.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Corpus Striatum; Dizocilpine Maleate; Glutamic Acid; Magnesium; Male; Microdialysis; Prosencephalon; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
Changes in amino acid release and membrane potential during cerebral hypoxia and glucose deprivation.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Glucose; Glutamic Acid; Hippocampus; Hypoxia, Brain; Membrane Potentials; Rats; Rats, Wistar; Time Factors | 1995 |
Effects of a glutamate uptake inhibitor on glutamate release induced by veratridine and ischemia.
Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Brain Ischemia; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Microdialysis; Neurotransmitter Uptake Inhibitors; Rats; Rats, Wistar; Veratridine | 1995 |
PAF antagonist, BN52021, inhibits [3H]D-aspartate release after ischaemia in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aspartic Acid; Brain Ischemia; Diterpenes; Enzyme Activation; Ginkgolides; Hippocampus; In Vitro Techniques; Isoquinolines; Lactones; Phorbol 12,13-Dibutyrate; Piperazines; Platelet Activating Factor; Potassium; Protein Kinase C; Rats; Rats, Wistar; Tritium | 1994 |
Astrocytic swelling due to hypotonic or high K+ medium causes inhibition of glutamate and aspartate uptake and increases their release.
Topics: Animals; Aspartic Acid; Astrocytes; Brain; Brain Edema; Brain Ischemia; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypotonic Solutions; Potassium; Rats; Temperature | 1995 |
A possible role for phospholipases in the release of neurotransmitter amino acids from ischemic rat cerebral cortex.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Phospholipases; Rats; Rats, Sprague-Dawley | 1995 |
Changes in metabolites and tissue water status after focal ischemia in cat brain assessed with localized proton MR spectroscopy.
Topics: Animals; Aspartic Acid; Body Water; Brain; Brain Ischemia; Cats; Creatine; Diffusion; Female; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Time Factors | 1994 |
Proton magnetic resonance spectroscopy in patients with ischemic stroke.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Ischemia; Case-Control Studies; Choline; Creatine; Female; Humans; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine | 1994 |
Proton magnetic resonance spectroscopy in suspected vascular ischemic parkinsonism.
Topics: Aged; Aspartic Acid; Brain; Brain Ischemia; Brain Mapping; Energy Metabolism; Female; Humans; Intracranial Arteriosclerosis; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Parkinson Disease; Regional Blood Flow | 1994 |
Protein synthesis and energy metabolism in hippocampal slices during extended (24 hours) recovery following different periods of ischemia.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain Ischemia; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Nerve Tissue Proteins; Rats | 1994 |
Glucose can fuel glutamate uptake in ischemic brain.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Glucose; Glutamates; Glutamic Acid; Male; Microdialysis; Osmolar Concentration; Rats; Rats, Sprague-Dawley | 1994 |
Excitatory amino acids in the cerebrospinal fluid of asphyxiated infants: relationship to hypoxic-ischemic encephalopathy.
Topics: Amino Acids; Aspartic Acid; Asphyxia Neonatorum; Brain Ischemia; Child, Preschool; Chromatography, Liquid; Glutamates; Glutamic Acid; Humans; Hypoxia, Brain; Infant; Infant, Newborn; Infant, Premature; Neurotransmitter Agents; Severity of Illness Index; Taurine | 1993 |
Characterization of glutamate, aspartate, and GABA release from ischemic rat cerebral cortex.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Brain Ischemia; Cerebral Cortex; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycoproteins; L-Lactate Dehydrogenase; Male; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1994 |
Indomethacin modulates ischemia-evoked release of glutamate and adenosine from the rat cerebral cortex.
Topics: Adenosine; Animals; Aspartic Acid; Blood Pressure; Brain Ischemia; Cell Death; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Glutamic Acid; Indomethacin; Rats; Rats, Sprague-Dawley; Reperfusion | 1994 |
Neuroprotective effects of tetrodotoxin as a Na+ channel modulator and glutamate release inhibitor in cultured rat cerebellar neurons and in gerbil global brain ischemia.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gerbillinae; Glutamic Acid; Hippocampus; Ion Transport; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Sodium Channel Blockers; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin; Veratridine | 1994 |
Glucocorticoids increase extracellular [3H]D-aspartate overflow in hippocampal cultures during cyanide-induced ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cyanides; Extracellular Space; Glucocorticoids; Hippocampus; Kinetics; Organ Culture Techniques; Rats; Rats, Sprague-Dawley | 1994 |
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebrovascular Disorders; Choline; Creatine; Follow-Up Studies; Humans; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Meningioma; Middle Aged; Protons | 1994 |
In situ changes in purine nucleotide and N-acetyl concentrations upon inducing global ischemia in cat brain.
Topics: Acetylation; Adenosine; Animals; Aspartic Acid; Brain Ischemia; Cats; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Magnetic Resonance Spectroscopy; Male; Purine Nucleotides; Taurine | 1993 |
Sustained changes in acetylcholine and amino acid contents of brain regions following microsphere embolism in rats.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Intracranial Embolism and Thrombosis; Male; Microspheres; Rats; Rats, Wistar; Taurine; Tetrazolium Salts | 1993 |
Magnetic resonance spectroscopy of N-acetylaspartate in hypoxic-ischemic encephalopathy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Ischemia; Humans; Hypoxia, Brain; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male | 1994 |
[1H magnetic resonance spectroscopy in intracranial tumors and cerebral ischemia].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Child; Child, Preschool; Choline; Female; Glioma; Humans; Lactates; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Oligodendroglioma; Supratentorial Neoplasms | 1993 |
A highly sensitive lactate editing technique for surface coil spectroscopic imaging in vivo.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Electron Spin Resonance Spectroscopy; Image Enhancement; Lactates; Lipids; Magnetic Resonance Spectroscopy; Magnetics; Models, Structural; Models, Theoretical; Phosphocreatine; Rats; Signal Processing, Computer-Assisted; Water | 1993 |
Lowered brain glutathione by diethylmaleate decreased the glutamate release induced by cerebral ischemia in anesthetized rats.
Topics: Anesthetics; Animals; Aspartic Acid; Brain; Brain Ischemia; Glutamic Acid; Glutathione; In Vitro Techniques; Male; Maleates; Microdialysis; Rats; Rats, Sprague-Dawley | 1995 |
Effects of hypothermia on the rate of excitatory amino acid release after ischemic depolarization.
Topics: Analysis of Variance; Animals; Aspartic Acid; Body Temperature; Brain Ischemia; Cerebral Cortex; Electroencephalography; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Heart Arrest; Hypothermia, Induced; Male; Membrane Potentials; Microdialysis; Rats; Rats, Sprague-Dawley | 1996 |
Regional gray and white matter metabolite differences in subjects with AD, with subcortical ischemic vascular dementia, and elderly controls with 1H magnetic resonance spectroscopic imaging.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Aspartic Acid; Brain; Brain Ischemia; Cerebral Cortex; Choline; Creatine; Cross-Sectional Studies; Dementia, Vascular; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Tissue; Phosphocreatine; Protons | 1996 |
Neuroexcitatory amino acids and their relation to infarct size and neurological deficit in ischemic stroke.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Excitatory Amino Acids; Female; Glutamic Acid; Glycine; Humans; Logistic Models; Male; Middle Aged; Neurologic Examination; Severity of Illness Index; Taurine; Tomography, X-Ray Computed | 1996 |
Evolution of acute focal cerebral ischaemia in rats observed by localized 1H MRS, diffusion-weighted MRI, and electrophysiological monitoring.
Topics: Acute Disease; Animals; Aspartic Acid; Brain Ischemia; Electroencephalography; Electrophysiology; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic; Protons; Rats; Rats, Wistar | 1995 |
A use-dependent sodium channel antagonist, 619C89, in reduction of ischemic brain damage and glutamate release after acute subdural hematoma in the rat.
Topics: Animals; Aspartic Acid; Brain Ischemia; Dialysis; Disease Models, Animal; Glutamic Acid; Hematoma, Subdural; Male; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Threonine | 1996 |
Effects of hypothermia, pentobarbital, and isoflurane on postdepolarization amino acid release during complete global cerebral ischemia.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypnotics and Sedatives; Hypothermia, Induced; Isoflurane; Male; Pentobarbital; Rats; Rats, Sprague-Dawley | 1996 |
Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ischemic injury in late gestation fetal sheep.
Topics: Animals; Aspartic Acid; Brain Edema; Brain Ischemia; Cytotoxins; Electroencephalography; Extracellular Space; Female; Fetal Hypoxia; gamma-Aminobutyric Acid; Gestational Age; Glutamic Acid; Hypoxia, Brain; Nitric Oxide; Pregnancy; Reperfusion Injury; Seizures; Sheep; Time Factors | 1996 |
Proton MR spectroscopy in acute middle cerebral artery stroke.
Topics: Acute Disease; Aged; Artifacts; Aspartic Acid; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Cerebrovascular Disorders; Feasibility Studies; Female; Humans; Lactates; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons | 1996 |
Intracerebral microdialysis of glutamate and aspartate in two vascular territories after aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Aspartic Acid; Brain Ischemia; Female; Frontal Lobe; Glutamic Acid; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Postoperative Complications; Prognosis; Subarachnoid Hemorrhage; Synaptic Transmission; Temporal Lobe; Tomography, X-Ray Computed | 1996 |
Mapping of lactate and N-acetyl-L-aspartate predicts infarction during acute focal ischemia: in vivo 1H magnetic resonance spectroscopy in rats.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Ischemia; Cerebral Infarction; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Prognosis; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1996 |
Hypoglycemia prevents increase in lactic acidosis during reperfusion after temporary cerebral ischemia in rats.
Topics: Acidosis, Lactic; Animals; Aspartic Acid; Blood Glucose; Brain Ischemia; Energy Metabolism; Hydrogen-Ion Concentration; Hypoglycemia; Lactates; Magnetic Resonance Spectroscopy; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1995 |
99Tcm-HMPAO SPET and 1H-MRS (proton magnetic resonance spectroscopy) in patients with ischaemic cerebral infarction.
Topics: Adult; Aged; Aspartic Acid; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Choline; Creatine; Female; Humans; Lactates; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Organotechnetium Compounds; Oximes; Phosphocreatine; Protons; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon | 1996 |
Enhancement of 3[H]D-aspartate release during ischemia like conditions in rat hippocampal slices: source of excitatory amino acids.
Topics: Animals; Aspartic Acid; Brain Ischemia; Chelating Agents; Egtazic Acid; Hippocampus; In Vitro Techniques; Rats; Tetrodotoxin | 1996 |
Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamic Acid; Lipoxygenase Inhibitors; Male; Phospholipases; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley | 1996 |
Diffusion of metabolites in normal and ischemic rat brain measured by localized 1H MRS.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Diffusion; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Rats; Rats, Inbred F344; Water | 1996 |
[Low-energy He-Ne-laser-induced neurochemical changes during brain ischemia/reperfusion and their integral estimation using a factor analysis model].
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Brain; Brain Ischemia; Factor Analysis, Statistical; Glutamic Acid; Laser Therapy; Male; Phospholipids; Rats; Reperfusion Injury | 1996 |
Transient elevation of interstitial N-acetylaspartate in reversible global brain ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Extracellular Space; Male; Mannitol; Membrane Potentials; Microdialysis; Potassium; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Tritium | 1997 |
In vivo proton magnetic resonance spectroscopy for metabolic changes in brain during chronic cerebral vasospasm in primates.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebral Angiography; Cerebrovascular Circulation; Choline; Chronic Disease; Cognition Disorders; Creatinine; Energy Metabolism; Female; Ischemic Attack, Transient; Macaca fascicularis; Magnetic Resonance Imaging; Neurons; Phosphocreatine; Subarachnoid Hemorrhage | 1997 |
Modulation of ischemic excitatory neurotransmitter and gamma-aminobutyric acid release during global temporary cerebral ischemia by selective neuronal nitric oxide synthase inhibition.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Indazoles; Male; Microdialysis; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1997 |
Modulation of ischemic excitatory neurotransmitter and gamma-aminobutyric acid release during global temporary cerebral ischemia by local nitric oxide synthase inhibition.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion | 1997 |
Effect of brain, body, and magnet bore temperatures on energy metabolism during global cerebral ischemia and reperfusion monitored by magnetic resonance spectroscopy in rats.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Body Temperature; Brain; Brain Ischemia; Energy Metabolism; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reperfusion; Temperature | 1997 |
Effects of severe global ischemia on N-acetylaspartate and other metabolites in the rat brain.
Topics: Alanine; Animals; Aspartic Acid; Brain; Brain Ischemia; Creatine; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar | 1997 |
Inhibition by anion channel blockers of ischemia-evoked release of excitotoxic and other amino acids from rat cerebral cortex.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamic Acid; Ion Channels; Male; Nitrobenzoates; Rats; Rats, Sprague-Dawley | 1997 |
[Evaluation of cerebral ischemia with metabolic image by using 3D-CSI--comparing with SPECT and PET].
Topics: Amphetamines; Aspartic Acid; Brain; Brain Ischemia; Humans; Image Enhancement; Iodine Radioisotopes; Iofetamine; Magnetic Resonance Spectroscopy; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1997 |
Early cerebral-metabolite quantification in perinatal hypoxic-ischaemic encephalopathy by proton and phosphorus magnetic resonance spectroscopy.
Topics: Adenosine Triphosphate; Aspartic Acid; Brain Diseases, Metabolic; Brain Ischemia; Humans; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Thalamus | 1997 |
[Accuracy and clinical utility of quantitative proton magnetic resonance spectroscopy (MRS) on phantom and chronic cerebral ischemia].
Topics: Aspartic Acid; Brain; Brain Ischemia; Chronic Disease; Creatine; Humans; Magnetic Resonance Spectroscopy; Phantoms, Imaging; Phosphocreatine; Sensitivity and Specificity | 1997 |
Neurometabolism of active neuropsychiatric lupus determined with proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Damage, Chronic; Brain Ischemia; Brain Mapping; Choline; Creatine; Energy Metabolism; Female; Humans; Lactic Acid; Lipid Metabolism; Lupus Erythematosus, Systemic; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurocognitive Disorders; Neurons; Reference Values | 1997 |
MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Choline; Creatine; Eclampsia; Energy Metabolism; Female; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Obstetric Labor Complications; Pregnancy; Prognosis | 1997 |
Effects of electroacupuncture on extracellular contents of amino acid neurotransmitters in rat striatum following transient focal cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Infarction; Chromatography, High Pressure Liquid; Corpus Striatum; Electroacupuncture; Excitatory Amino Acids; Fluorescence; Glutamic Acid; Male; Microdialysis; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Taurine | 1997 |
Exocytotic and nonexocytotic modes of glutamate release from cultured cerebellar granule cells during chemical ischaemia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Aspartic Acid; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebellum; Cytoplasm; Deoxyglucose; Dizocilpine Maleate; Exocytosis; Fluorescent Dyes; Glutamic Acid; Macrolides; Neurons; omega-Conotoxins; Peptides; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Cyanide; Tetanus Toxin; Time Factors | 1998 |
Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Energy Metabolism; Excitatory Amino Acids; Glutamic Acid; Hypoxanthine; Hypoxia; Malondialdehyde; Rats; Rats, Wistar; Xanthine | 1998 |
Proton T2 relaxation of cerebral metabolites during transient global ischemia in rat brain.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Image Processing, Computer-Assisted; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Wistar | 1998 |
Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions.
Topics: Aging; Animals; Aspartic Acid; Brain Ischemia; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Potassium; Taurine | 1998 |
Corticosterone exacerbates cyanide-induced cell death in hippocampal cultures: role of astrocytes.
Topics: Animals; Aspartic Acid; Astrocytes; Brain Ischemia; Cell Death; Cells, Cultured; Corticosterone; Cyanides; Drug Synergism; Fetus; Hippocampus; Neurons; Rats; Rats, Sprague-Dawley; Tritium | 1998 |
Changes in brain organic osmolytes in experimental cerebral ischemia.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Brain Ischemia; Creatine; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Magnetic Resonance Spectroscopy; Male; Methylamines; Phosphocreatine; Rats; Rats, Sprague-Dawley; Taurine | 1998 |
Peroxynitrite causes aspartate release from dissociated rat cerebellar granule neurones.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Cerebellar Cortex; Dithiothreitol; Egtazic Acid; Glutamic Acid; Ion Transport; Kainic Acid; Membrane Proteins; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Oxidants; Oxidation-Reduction; Rats; Rats, Wistar; Sodium; Sulfhydryl Compounds; Superoxides; Tetrodotoxin | 1998 |
Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Edema; Brain Ischemia; Cerebral Arteries; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular Disorders; Choline; Follow-Up Studies; Humans; Lactates; Magnetic Resonance Imaging; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Protons; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 1998 |
Modulation of ischemia-evoked release of excitatory and inhibitory amino acids by adenosine A1 receptor agonist.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; gamma-Aminobutyric Acid; Glutamic Acid; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred SHR; Regional Blood Flow; Taurine | 1998 |
[The effect of wuto granules on the levels of excitatory amino acids in extracellullar fluid of rat hippocampus following cerebral ischemia].
Topics: Animals; Aspartic Acid; Blood-Brain Barrier; Brain Ischemia; Drugs, Chinese Herbal; Excitatory Amino Acids; Extracellular Space; Female; Glutamic Acid; Hippocampus; Male; Microdialysis; Rats; Rats, Wistar | 1997 |
Effect of temperature on the kinetics of lactate production and clearance in a rat model of forebrain ischemia.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Ischemia; Energy Metabolism; Hypothermia, Induced; Kinetics; Lactates; Magnetic Resonance Spectroscopy; Male; Metabolic Clearance Rate; Oxidative Phosphorylation; Prosencephalon; Protons; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Temperature | 1998 |
Inhibition of ischemia-induced glutamate release in rat striatum by dihydrokinate and an anion channel blocker.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Blood Flow Velocity; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Corpus Striatum; Drug Therapy, Combination; Glutamic Acid; Ion Pumps; Kainic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Stilbenes | 1999 |
N-Acetylaspartate distribution in rat brain striatum during acute brain ischemia.
Topics: Acute Disease; Animals; Aspartic Acid; Brain Ischemia; Cerebral Infarction; Corpus Striatum; Magnetic Resonance Spectroscopy; Male; Mannitol; Microdialysis; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1999 |
[Levels of neurotransmitter amino acids in the cerebrospinal fluid of patients with acute ischemic stroke].
Topics: Acute Disease; Aspartic Acid; Brain Ischemia; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurotransmitter Agents; Prognosis; Time Factors | 1999 |
Neurone-specific enolase and N-acetyl-aspartate as potential peripheral markers of ischaemic stroke.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Disorders; Female; Humans; Infarction; Male; Middle Aged; Neurons; Phosphopyruvate Hydratase; Time Factors; Tomography | 1999 |
Metabolite changes in neonatal rat brain during and after cerebral hypoxia-ischemia: a magnetic resonance spectroscopic imaging study.
Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Female; Hypoxia, Brain; Lactic Acid; Magnetic Resonance Imaging; Pregnancy; Protons; Rats; Rats, Wistar | 1999 |
No association between Glu/Asp polymorphism of NOS3 gene and ischemic stroke.
Topics: Aged; Alleles; Aspartic Acid; Brain Ischemia; Cerebrovascular Disorders; Female; Genotype; Glutamic Acid; Humans; Male; Middle Aged; Nitric Oxide Synthase; Odds Ratio; Polymorphism, Genetic | 1999 |
Decrease in N-acetylaspartate without commensurate accumulation of acetate in focal cerebral ischemia in rat.
Topics: Acetates; Animals; Aspartic Acid; Brain; Brain Ischemia; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Sprague-Dawley | 1999 |
Relating MRI changes to motor deficit after ischemic stroke by segmentation of functional motor pathways.
Topics: Adult; Aged; Aspartic Acid; Brain Ischemia; Disability Evaluation; Female; Humans; Internal Capsule; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Movement Disorders; Neural Pathways; Pyramidal Tracts; Stroke | 2000 |
Regional alterations in an excitatory amino-acid transporter, blood flow, and glucose metabolism after middle cerebral artery occlusion in the rat.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Autoradiography; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Deoxyglucose; Glucose; Iofetamine; Male; Middle Cerebral Artery; Radiopharmaceuticals; Rats; Rats, Wistar; Regional Blood Flow; Regression Analysis; Tritium | 2000 |
Topical glucose and accumulation of excitotoxic and other amino acids in ischemic cerebral cortex.
Topics: Animals; Aspartic Acid; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Cortex; Ethanolamines; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Hyperglycemia; Male; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Taurine | 2000 |
Applying functional MR imaging to brain-behavioral research: can we do better than simple clinical measures?
Topics: Aspartic Acid; Brain; Brain Ischemia; Creatine; Dementia, Vascular; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 2000 |
Subcortical ischemic vascular dementia: assessment with quantitative MR imaging and 1H MR spectroscopy.
Topics: Aged; Aspartic Acid; Brain Ischemia; Creatine; Dementia, Vascular; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male | 2000 |
Acute decrease in net glutamate uptake during energy deprivation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Biological Transport; Brain Ischemia; Dicarboxylic Acids; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Organ Culture Techniques; Patch-Clamp Techniques; Pyrrolidines; Quinoxalines; Rats | 2000 |
Transporter reversal as a mechanism of glutamate release from the ischemic rat cerebral cortex: studies with DL-threo-beta-benzyloxyaspartate.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain Ischemia; Cerebral Cortex; Glutamic Acid; Hydrogen-Ion Concentration; Lactic Acid; Male; Neurotoxins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Taurine | 2000 |
The effect of topical insulin on the release of excitotoxic and other amino acids from the rat cerebral cortex during streptozotocin-induced hyperglycemic ischemia.
Topics: Administration, Topical; Animals; Aspartic Acid; Blood Glucose; Brain Ischemia; Cerebral Cortex; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acids; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hyperglycemia; Insulin; Lactic Acid; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Taurine | 2000 |
No association between Glu/Asp polymorphism of NOS3 gene and ischemic stroke.
Topics: Adolescent; Aspartic Acid; Brain Ischemia; Child; Child, Preschool; Genetic Linkage; Glutamic Acid; Humans; Infant; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Polymorphism, Genetic; Stroke | 2000 |
Influence of different anaesthetics on extracellular aminoacids in rat brain.
Topics: Amino Acids; Anesthetics; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Extracellular Space; Glutamic Acid; Glycine; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Wistar | 2000 |
Hypothermia inhibits ischemia-induced efflux of amino acids and neuronal damage in the hippocampus of aged rats.
Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Excitatory Amino Acids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Hypothermia, Induced; Nerve Degeneration; Neural Inhibition; Neurons; Rats; Rats, Inbred SHR; Taurine | 2000 |
Magnetic resonance techniques for the identification of patients with symptomatic carotid artery occlusion at high risk of cerebral ischemic events.
Topics: Adult; Aged; Aspartic Acid; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Choline; Comorbidity; Female; Follow-Up Studies; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Outcome Assessment, Health Care; Prognosis; Radiography; Recurrence; Retinal Artery Occlusion; Risk Factors | 2000 |
N-acetylaspartate distribution in proton spectroscopic images of ischemic stroke: relationship to infarct appearance on T2-weighted magnetic resonance imaging.
Topics: Acute Disease; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Stroke | 2000 |
Inhibition of evoked glutamate release by the neuroprotective 5-HT(1A) receptor agonist BAY x 3702 in vitro and in vivo.
Topics: Animals; Aspartic Acid; Benzopyrans; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Hippocampus; Infarction, Middle Cerebral Artery; Male; Microdialysis; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Synaptic Transmission; Thiazoles | 2001 |
Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Brain Ischemia; Case-Control Studies; Cerebral Ventricles; Child; Child Abuse; Child, Preschool; Disabled Persons; Excitatory Amino Acids; Glasgow Coma Scale; Glasgow Outcome Scale; Glutamic Acid; Glycine; Humans; Infant; Prognosis; Survival Analysis; Time Factors; Tomography, X-Ray Computed | 2001 |
Effect of acute alcohol on ischemia-induced glutamate release and brain damage.
Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Brain Ischemia; Ethanol; Frontal Lobe; Glutamic Acid; Kinetics; Male; Necrosis; Rats; Rats, Wistar; Rose Bengal | 2000 |
Characterization of transient focal ischemia-induced increases in extracellular glutamate and aspartate in spontaneously hypertensive rats.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain; Brain Ischemia; Extracellular Space; Glutamic Acid; Infarction, Middle Cerebral Artery; Kainic Acid; Male; Rats; Rats, Inbred SHR; Reperfusion Injury; Tetrodotoxin; Time Factors | 2000 |
Real-time, two-dimensional visualization of ischaemia-induced glutamate release from hippocampal slices.
Topics: Alanine; Aspartic Acid; Brain Ischemia; Calcium Signaling; Cell Line; Computer Systems; Dentate Gyrus; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Hot Temperature; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Microscopy, Video; Potassium; Receptors, N-Methyl-D-Aspartate; Solutions; Taurine | 2001 |
Mismatch between lactate and the apparent diffusion coefficient of water in progressive focal ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Diffusion; Lactic Acid; Ligation; Magnetic Resonance Spectroscopy; Male; Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Spectrum Analysis; Water | 2001 |
N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury.
Topics: 2,2'-Dipyridyl; Acute Disease; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Edema; Brain Ischemia; Carotid Arteries; Cell Death; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Injections, Intra-Arterial; Iron Chelating Agents; Male; Malonates; Microspheres; Mitochondria; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Nitro Compounds; Oxidative Stress; Premedication; Propionates; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Succinate Dehydrogenase | 2001 |
Metabolic changes in the ischemic penumbra after carotid endarterectomy in stroke patients by localized in vivo proton magnetic resonance spectroscopy (1H-MRS).
Topics: Aged; Aspartic Acid; Brain Ischemia; Carotid Stenosis; Cerebral Infarction; Choline; Creatine; Endarterectomy, Carotid; Energy Metabolism; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Postoperative Complications; Regional Blood Flow; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2001 |
1H magnetic resonance spectroscopic imaging of permanent focal cerebral ischemia in rat: longitudinal metabolic changes in ischemic core and rim.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Ischemia; Caudate Nucleus; Circle of Willis; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Gyrus Cinguli; Ligation; Magnetic Resonance Imaging; Male; Necrosis; Putamen; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Time Factors | 2001 |
Metabolic changes in pericontusional oedematous areas in mild head injury evaluated by 1H MRS.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Concussion; Brain Edema; Brain Ischemia; Creatine; Energy Metabolism; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons | 2000 |
Quantitative evaluation of cerebral metabolites and cerebral blood flow in patients with carotid stenosis.
Topics: Adult; Aged; Aging; Aspartic Acid; Basal Ganglia; Brain Ischemia; Carotid Stenosis; Cerebral Cortex; Cerebrovascular Circulation; Choline; Creatine; Endarterectomy, Carotid; Energy Metabolism; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Recovery of Function; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2001 |
Effects of sevoflurane on dopamine, glutamate and aspartate release in an in vitro model of cerebral ischaemia.
Topics: Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; Corpus Striatum; Culture Techniques; Dopamine; Glutamic Acid; Male; Methyl Ethers; Neurotransmitter Agents; Rats; Rats, Wistar; Sevoflurane | 2001 |
A potent AMPA/kainate receptor antagonist, YM90K, attenuates the loss of N-acetylaspartate in the hippocampal CA1 area after transient unilateral forebrain ischemia in gerbils.
Topics: Animals; Aspartic Acid; Brain Ischemia; Chromatography, High Pressure Liquid; Excitatory Amino Acid Antagonists; Gerbillinae; Hippocampus; Male; Prosencephalon; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid | 2001 |
In vivo cellular uptake of glutamate is impaired in the rat hippocampus during and after transient cerebral ischemia: a microdialysis extraction study.
Topics: Animals; Aspartic Acid; Brain Ischemia; Carrier Proteins; Enzyme Inhibitors; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission; Tritium | 2001 |
Diffusion-weighted in vivo localized proton MR spectroscopy of human cerebral ischemia and tumor.
Topics: Adult; Aspartic Acid; Brain Ischemia; Brain Neoplasms; Cerebral Infarction; Creatine; Diffusion; Female; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Viscosity | 2002 |
Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Aspartic Acid; Atrophy; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; Child; Choline; Creatine; Female; Frontal Lobe; Humans; Hydrogen; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine | 1992 |
Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Purinergic Antagonists; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Triazoles; Xanthines | 1992 |
1H spectroscopic imaging of rat brain at 7 tesla.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Choline; Creatine; Glutamates; Glutamic Acid; Magnetic Resonance Spectroscopy; Phosphocreatine; Rats; Rats, Inbred F344 | 1992 |
Adenosine receptor blockade augments interstitial fluid levels of excitatory amino acids during cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Glutamates; Glutamic Acid; Hypoxanthine; Hypoxanthines; Male; Neurotoxins; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Xanthine; Xanthines | 1992 |
Concomitant increases in the extracellular concentrations of excitatory and inhibitory amino acids in the rat hippocampus during forebrain ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Cell Death; Consciousness; Ethanolamines; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hippocampus; Male; Neurotoxins; Prosencephalon; Rats; Rats, Inbred Strains; Taurine | 1992 |
Striatal protection induced by lesioning the substantia nigra of rats subjected to focal ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Infarction; Corpus Striatum; Dopamine; Extracellular Space; Glutamates; Glutamic Acid; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1992 |
Proton spectroscopic imaging in cerebral ischaemia. Where we stand and what can be expected.
Topics: Aspartic Acid; Brain; Brain Ischemia; Brain Mapping; Choline; Energy Metabolism; Humans; Image Interpretation, Computer-Assisted; Ischemic Attack, Transient; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurotransmitter Agents; Phosphocreatine; Phosphorus; Protons; Regional Blood Flow | 1992 |
In vivo relaxation of N-acetyl-aspartate, creatine plus phosphocreatine, and choline containing compounds during the course of brain infarction: a proton MRS study.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Phosphocreatine | 1992 |
Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cerebral Infarction; Choline; Chronic Disease; Creatine; Female; Humans; Hydrogen; Image Enhancement; Inositol; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged | 1992 |
Effects of hyperglycemia on the time course of changes in energy metabolism and pH during global cerebral ischemia and reperfusion in rats: correlation of 1H and 31P NMR spectroscopy with fatty acid and excitatory amino acid levels.
Topics: Acidosis, Lactic; Animals; Aspartic Acid; Brain Chemistry; Brain Ischemia; Energy Metabolism; Fatty Acids, Nonesterified; Hydrogen-Ion Concentration; Hyperglycemia; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Reperfusion | 1992 |
Characterization of D-aspartic acid uptake by rat hippocampal slices and effect of ischemic conditions.
Topics: Animals; Aspartic Acid; Biological Transport; Brain Ischemia; Cells, Cultured; Glutamates; Hippocampus; Male; Rats; Rats, Inbred Strains; Sodium; Time Factors; Tritium | 1992 |
Correlation of the extracellular glutamate concentration with extent of blood flow reduction after subdural hematoma in the rat.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Flow Velocity; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutamates; Glutamic Acid; Glutamine; Hematoma, Subdural; Male; Rats; Rats, Inbred Strains; Regression Analysis; Valine | 1991 |
The effects of hypothermia on amino acid neurotransmitter release from the cerebral cortex.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hypothermia, Induced; Male; Rats; Rats, Inbred Strains; Secretory Rate | 1991 |
Ischemia does not induce the release of excitotoxic amino acids from the hippocampus of newborn rats.
Topics: Aging; Allopurinol; Animals; Animals, Newborn; Aspartic Acid; Brain Ischemia; Free Radicals; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Rats; Rats, Inbred Strains | 1991 |
Differences in transmitter release, morphology, and ischemia-induced cell injury between cerebellar granule cell cultures developing in the presence and in the absence of a depolarizing potassium concentration.
Topics: Animals; Aspartic Acid; Brain Ischemia; Calcium; Cell Count; Cell Hypoxia; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Immunochemistry; Membrane Potentials; Mice; Microscopy, Electron; Neurons; Potassium; Synaptophysin | 1991 |
K+ efflux pathways and neurotransmitter release associated to hippocampal ischemia: effects of glucose and of K+ channel blockers.
Topics: 4-Aminopyridine; Animals; Apamin; Aspartic Acid; Barium; Barium Compounds; Brain Ischemia; Calcium Chloride; Charybdotoxin; Chlorides; Elapid Venoms; gamma-Aminobutyric Acid; Glipizide; Glucose; Glyburide; Hippocampus; In Vitro Techniques; Kinetics; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Rubidium; Scorpion Venoms; Tetraethylammonium; Tetraethylammonium Compounds | 1991 |
Effects of hypoxia-ischemia and MK-801 treatment on the binding of a phencyclidine analogue in the developing rat brain.
Topics: Animals; Animals, Newborn; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hypoxia; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Tritium | 1990 |
Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Free Radicals; Glutamates; Glutamic Acid; Male; Neurons; Oxygen; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Time-sequential change of amino acid neurotransmitters--GABA, aspartate and glutamate--in the rat basal ganglia following middle cerebral artery occlusion.
Topics: Animals; Aspartic Acid; Basal Ganglia; Brain Ischemia; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Substantia Nigra | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Pyramidal Tracts; Quinoxalines; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1990 |
Protection by NMDA antagonists against selective cell loss following transient ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Neurons; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
NMDA receptors trigger excitement.
Topics: Aspartic Acid; Brain; Brain Ischemia; Cell Survival; Cerebrovascular Disorders; Electrophysiology; Glutamates; Glutamic Acid; Glycine; Heart Diseases; Humans; Ion Channels; Learning; Memory; Neurons; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1988 |
Cerebral metabolism in man after acute stroke: new observations using localized proton NMR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; gamma-Aminobutyric Acid; Humans; Lactates; Magnetic Resonance Spectroscopy; Male; Protons | 1989 |
Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Brain; Brain Ischemia; Cerebral Ventricles; Corpus Striatum; Electric Conductivity; Female; Gerbillinae; In Vitro Techniques; Male; Membranes; N-Methylaspartate; Oocytes; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Xenopus | 1989 |
Excitatory amino acid binding sites in the rat hippocampus after transient forebrain ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Binding Sites; Brain Ischemia; Diencephalon; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Telencephalon | 1989 |
Sensitivity of the developing rat brain to hypobaric/ischemic damage parallels sensitivity to N-methyl-aspartate neurotoxicity.
Topics: Air Pressure; Animals; Animals, Newborn; Aspartic Acid; Atmospheric Pressure; Brain; Brain Ischemia; Disease Susceptibility; Microinjections; N-Methylaspartate; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains | 1989 |
Effect of the NMDA antagonist MK-801 on local cerebral blood flow in focal cerebral ischaemia in the rat.
Topics: Animals; Aspartic Acid; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Rats; Rats, Inbred Strains | 1989 |
Evaluation of a newly discovered water suppression pulse sequence for high-field in vivo 1H surface coil NMR spectroscopy.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cats; Fatty Acids; Female; Lactates; Magnetic Resonance Spectroscopy; Male | 1989 |
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cells, Cultured; Cerebellum; Corpus Striatum; Cyclic GMP; Dopamine; Harmaline; In Vitro Techniques; Mice; N-Methylaspartate; Phencyclidine; Piperazines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spinal Cord | 1988 |
Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cats; Female; Male; Models, Cardiovascular; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Vasoconstriction | 1988 |
Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders.
Topics: Adult; Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Glutamates; Humans; Hypoxia, Brain; Infant; N-Methylaspartate; Nerve Degeneration; Neurotransmitter Agents; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1985 |
Elevated concentrations of glutamate and aspartate in human ventricular cerebrospinal fluid (vCSF) during episodes of increased CSF pressure and clinical signs of impaired brain circulation.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Brain Ischemia; Female; Glutamates; Glutamic Acid; Humans; Hydrocephalus; Intracranial Pressure; Male; Middle Aged; Osmolar Concentration; Tomography, X-Ray Computed | 1985 |
Endogenous excitotoxins as possible mediators of ischemic and hypoglycemic brain damage.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Calcium; Corpus Striatum; Glutamates; Hypoglycemia; Neurotransmitter Agents; Potassium; Rats; Receptors, AMPA; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1986 |
Inhibition of excitatory neurotransmission with kynurenate reduces brain edema in neonatal anoxia.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Edema; Brain Ischemia; Glutamates; Glutamic Acid; Hypoxia, Brain; Kynurenic Acid; Rats | 1986 |
[Regional and time-sequential changes in amino acid neurotransmitters after focal cerebral ischemia in the rat].
Topics: Amino Acids; Animals; Aspartic Acid; Basal Ganglia; Brain; Brain Ischemia; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Substantia Nigra; Time Factors | 1986 |
Extracellular overflow of glutamate, aspartate, GABA and taurine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia.
Topics: Amino Acids; Animals; Aspartic Acid; Asphyxia; Brain Ischemia; Cerebrovascular Circulation; Evoked Potentials, Somatosensory; Fetus; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypoxia, Brain; Sheep; Taurine; Telencephalon | 1987 |
Focal cerebral ischaemia in the cat: treatment with the glutamate antagonist MK-801 after induction of ischaemia.
Topics: Animals; Anticonvulsants; Aspartic Acid; Brain Ischemia; Cats; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; N-Methylaspartate | 1988 |
Selective sparing of NADPH-diaphorase neurons in neonatal hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Hypoxia; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Neuropeptide Y; Rats; Rats, Inbred Strains; Somatostatin | 1988 |
[Influence of excitatory amino acids on the outcome of cerebral ischemia].
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Calcium; Cell Survival; Chlorides; Glutamates; Humans; Neurons; Receptors, Amino Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium | 1987 |
Quantitative autoradiography of [3H]-MK-801 binding sites in mammalian brain.
Topics: Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Ischemia; Densitometry; Dibenzocycloheptenes; Dizocilpine Maleate; Gerbillinae; Glutamates; In Vitro Techniques; Muscle, Smooth, Vascular; N-Methylaspartate; Rats; Rats, Inbred Strains; Synaptic Membranes | 1988 |
Delayed treatment with dextromethorphan and dextrorphan reduces cerebral damage after transient focal ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Dextromethorphan; Dextrorphan; Levorphanol; Male; Morphinans; N-Methylaspartate; Rabbits | 1988 |
Acute cerebral ischaemia: concurrent changes in cerebral blood flow, energy metabolites, pH, and lactate measured with hydrogen clearance and 31P and 1H nuclear magnetic resonance spectroscopy. II. Changes during ischaemia.
Topics: Animals; Aspartic Acid; Brain; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Gerbillinae; Hydrogen; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphocreatine; Phosphorus | 1987 |
Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Electroencephalography; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Rabbits; Taurine | 1985 |