aspartic acid has been researched along with Central Nervous System Diseases in 18 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A slowly progressive sensory ataxia and tremor manifested at the age of 3 to 16 years and distal spasticity in adolescence." | 1.32 | Five new cases of a recently described leukoencephalopathy with high brain lactate. ( Aärimaa, T; Autti, T; Häkkinen, AM; Koillinen, H; Kuusi, T; Linnankivi, T; Lönnqvist, T; Lundbom, N; Pihko, H; Sainio, K; Valanne, L, 2004) |
| "Future studies on the effects of cocaine abuse should control for the effects of gender-specific neurotoxicity." | 1.30 | Gender effects on persistent cerebral metabolite changes in the frontal lobes of abstinent cocaine users. ( Chang, L; Ernst, T; Mehringer, CM; Strickland, T, 1999) |
| " Since toxicity is a prominent impediment, the possibility of therapeutic synergy may perhaps be explored at drastically reduced doses of PALA, combined with other modulating measures." | 1.27 | Weekly 5-fluorouracil combined with PALA: toxic and therapeutic effects in colorectal cancer. ( Camacho, FJ; Engstrom, PF; Green, MD; Greenwald, ES; Kaplan, BH; Muggia, FM; Wernz, JC, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, WE | 2 |
| Tal, A | 2 |
| Zhang, K | 1 |
| Babb, JS | 2 |
| Ratai, EM | 2 |
| González, RG | 2 |
| Gonen, O | 2 |
| Kirov, II | 1 |
| George, AE | 1 |
| Sadakane, Y | 1 |
| Konoha, K | 1 |
| Kawahara, M | 1 |
| Nakagomi, K | 1 |
| Hammarström, P | 1 |
| Sekijima, Y | 1 |
| White, JT | 1 |
| Wiseman, RL | 1 |
| Lim, A | 1 |
| Costello, CE | 1 |
| Altland, K | 1 |
| Garzuly, F | 1 |
| Budka, H | 1 |
| Kelly, JW | 1 |
| Linnankivi, T | 1 |
| Lundbom, N | 1 |
| Autti, T | 1 |
| Häkkinen, AM | 1 |
| Koillinen, H | 1 |
| Kuusi, T | 1 |
| Lönnqvist, T | 1 |
| Sainio, K | 1 |
| Valanne, L | 1 |
| Aärimaa, T | 1 |
| Pihko, H | 1 |
| Gujar, SK | 1 |
| Maheshwari, S | 1 |
| Björkman-Burtscher, I | 1 |
| Sundgren, PC | 1 |
| Davie, CA | 1 |
| Wenning, GK | 1 |
| Barker, GJ | 1 |
| Brennan, A | 1 |
| Quinn, N | 1 |
| Miller, DH | 1 |
| Stover, JF | 1 |
| Pleines, UE | 1 |
| Morganti-Kossmann, MC | 1 |
| Kossmann, T | 1 |
| Lowitzsch, K | 1 |
| Kempski, OS | 1 |
| Chang, L | 1 |
| Ernst, T | 1 |
| Strickland, T | 1 |
| Mehringer, CM | 1 |
| Jakobs, C | 1 |
| ten Brink, HJ | 1 |
| Divry, P | 2 |
| Rolland, MO | 1 |
| Kelley, RI | 1 |
| Stamas, JN | 1 |
| Olney, JW | 1 |
| Millan, MH | 1 |
| Wardley-Smith, B | 2 |
| Halsey, MJ | 2 |
| Meldrum, BS | 2 |
| Ransom, BR | 1 |
| Waxman, SG | 1 |
| Davis, PK | 1 |
| Mathieu, M | 1 |
| Gilman, SC | 1 |
| Colton, JS | 1 |
| Dutka, AJ | 1 |
| Boogaard, JS | 1 |
| Muggia, FM | 1 |
| Camacho, FJ | 1 |
| Kaplan, BH | 1 |
| Green, MD | 1 |
| Greenwald, ES | 1 |
| Wernz, JC | 1 |
| Engstrom, PF | 1 |
2 reviews available for aspartic acid and Central Nervous System Diseases
| Article | Year |
|---|---|
Magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Central Nervous System Diseases; Choline; Creatine; Humans; Lactic Acid; Magne | 2005 |
Excitotoxin-mediated neuron death in youth and old age.
Topics: Aging; Alzheimer Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases, Metabolic; Brain Inju | 1990 |
16 other studies available for aspartic acid and Central Nervous System Diseases
| Article | Year |
|---|---|
Structure-specific glial response in a macaque model of neuroAIDS: multivoxel proton magnetic resonance spectroscopic imaging at 3 Tesla.
Topics: Animals; Aspartic Acid; Brain Chemistry; Central Nervous System Diseases; Cerebrospinal Fluid; Choli | 2013 |
Early glial activation precedes neurodegeneration in the cerebral cortex after SIV infection: a 3D, multivoxel proton magnetic resonance spectroscopy study.
Topics: Animals; Aspartic Acid; Biomarkers; Central Nervous System Diseases; Cerebral Cortex; Choline; Creat | 2015 |
Quantification of structural alterations of L-Asp and L-Asn residues in peptides related to neuronal diseases by reversed-phase high-performance liquid chromatography.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Asparagine; Aspartic Acid; Central Nervous System Diseas | 2010 |
D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?
Topics: Amino Acid Sequence; Amyloid Neuropathies, Familial; Aspartic Acid; Blood-Brain Barrier; Central Ner | 2003 |
Five new cases of a recently described leukoencephalopathy with high brain lactate.
Topics: Adolescent; Aspartic Acid; Ataxia; Brain Chemistry; Brain Diseases, Metabolic; Brain Stem; Central N | 2004 |
MRS to differentiate multiple system atrophy from idiopathic Parkinson's disease.
Topics: Adult; Aged; Aspartic Acid; Basal Ganglia; Central Nervous System Diseases; Creatine; Humans; Magnet | 1993 |
Neurotransmitters in cerebrospinal fluid reflect pathological activity.
Topics: Adult; Aged; Asparagine; Aspartic Acid; Blood-Brain Barrier; Central Nervous System Diseases; Female | 1997 |
Gender effects on persistent cerebral metabolite changes in the frontal lobes of abstinent cocaine users.
Topics: Adult; Analysis of Variance; Aspartic Acid; Central Nervous System Diseases; Choline; Cocaine-Relate | 1999 |
Prenatal diagnosis of Canavan disease.
Topics: Aspartic Acid; Central Nervous System Diseases; Female; Fetal Diseases; Humans; Pregnancy; Prenatal | 1992 |
Quantification of N-acetyl-L-aspartic acid in urine by isotope dilution gas chromatography-mass spectrometry.
Topics: Aspartic Acid; Central Nervous System Diseases; Child; Child, Preschool; Gas Chromatography-Mass Spe | 1992 |
Effect of NMDA and 2-amino-7-phosphonoheptanoate focal injection into the ventrolateral thalamic nucleus on the high pressure neurological syndrome in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Central Nervous System Diseases; H | 1990 |
Anoxic injury of CNS white matter: protective effect of ketamine.
Topics: Action Potentials; Animals; Aspartic Acid; Central Nervous System Diseases; Glutamates; Hypoxia; Ket | 1990 |
Aspartoacylase deficiency and N-acetylaspartic aciduria in patients with Canavan disease.
Topics: Amidohydrolases; Aspartic Acid; Central Nervous System Diseases; Genes, Recessive; Humans; Metabolis | 1989 |
Effects of high pressure on the release of excitatory amino acids by brain synaptosomes.
Topics: Animals; Aspartic Acid; Central Nervous System Diseases; Cerebral Cortex; Decompression; Glutamates; | 1986 |
The effect of two novel dipeptide antagonists of excitatory amino acid neurotransmission on the high pressure neurological syndrome in the rat.
Topics: Animals; Aspartic Acid; Central Nervous System Diseases; Glutamates; Glutamine; High Pressure Neurol | 1987 |
Weekly 5-fluorouracil combined with PALA: toxic and therapeutic effects in colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Central Nervous System D | 1987 |