aspartic acid has been researched along with Cell Transformation, Neoplastic in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (26.19) | 18.7374 |
| 1990's | 15 (35.71) | 18.2507 |
| 2000's | 10 (23.81) | 29.6817 |
| 2010's | 5 (11.90) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Cravatt, BF; Firestone, AJ; Haigis, KM; Huang, BJ; Inguva, A; Kogan, SC; Long, AM; Predovic, M; Remsberg, JR; Shannon, K; Suciu, RM; Wong, JC; Zambetti, NA | 1 |
| Cormier, F; Dondi, E; Gardano, L; Guittat, L; Katzav, S; Laurienté, V; Razanadrakoto, L; Varin-Blank, N | 1 |
| Blyth, K; Bulusu, V; Cardaci, S; Fleming, S; Gottlieb, E; Kalna, G; Kamphorst, JJ; MacKay, G; MacKenzie, ED; Nixon, C; Schiavi, F; Stevenson, D; Strathdee, D; Tumanov, S; van den Broek, NJ; Vazquez, A; Zheng, L | 1 |
| Cai, S; Du, J; Jiang, J; Liu, L; Liu, Q; Sung, KL; Yan, X; Yang, L; Yang, Y; Yu, S; Zhang, H | 1 |
| Bell, KM; Chung, CH; Gu, G; Means, AL; Ray, KC; Washington, MK; Yan, J | 1 |
| Chang, Q; Du, J; Li, Z; Liu, Y; Meline, B; Ranheim, E; Ryu, MJ; Tan, LX; Wang, J; Wang, Z; Young, KH; Zhang, J | 1 |
| Del Rosso, M; Dini, G; Fanti, E; Funghini, S; Magnelli, L; Rifkin, DB; Witort, E | 1 |
| Cerione, RA; Hahn, K; Nolbant, P; Tu, SS; Wu, WJ; Yang, W | 1 |
| Kaberlein, JJ; Luo, RT; Polak, PE; Simone, F; Thirman, MJ | 1 |
| Ali, RC; Hansen, LA; Tennant, RW; Trempus, CS; Wei, SJ | 1 |
| Ishiyama, N; Lin, T; Lipkowitz, S; Park, M; Peschard, P | 1 |
| Meyer, RD; Mohammadi, M; Rahimi, N | 1 |
| Furitsu, T; Ikeda, H; Kanakura, Y; Kanayama, Y; Kitamura, Y; Kitayama, H; Mitsui, H; Oritani, K; Sugahara, H; Tsujimura, T | 1 |
| Abbondandolo, A; Bonatti, S; Bozzo, S; Miele, M; Moro, F; Ottaggio, L; Simili, M | 1 |
| Caligo, MA; Mariani, T; Piras, A; Rainaldi, G; Vatteroni, L | 1 |
| Stambrook, PJ; Wani, MA; Xu, X | 1 |
| Barrett, JC; Jonczyk, P; Lum, K; Tlsty, TD; White, A | 1 |
| Asano, K; Kakizoe, T; Machida, T; Ochiya, T; Ohishi, Y; Sakamoto, H; Sasaki, H; Sugimura, T; Terada, M; Yoshida, T | 1 |
| Gallyas, F; Konishi, Y; Kunishita, T; Satoh, J; Tabira, T; Takeuchi, AM | 1 |
| Alger, JR; Bonavita, S; Di Chiro, G; Duyn, JH; Lundbom, N; Raman, R; Tedeschi, G | 1 |
| Heinzlmann, M; Lang, SM; Loeschke, K; Stratakis, DF; Teschauer, W | 1 |
| Agnès, F; Chen, C; Gélinas, C | 1 |
| Beeche, M; Bodnar, AG; Chang, E; Chiu, CP; Frolkis, M; Jiang, XR; Jimenez, G; Kusler, B; Sage, M; Tlsty, TD; Wahl, GM | 1 |
| Basnakian, AG; James, SJ; Melnyk, S; Miller, BJ; Pogribna, M; Pogribny, IP | 1 |
| Hei, TK; Piao, CQ | 1 |
| Akiyama, H; Asou, N; Kiyoi, H; Kodera, Y; Kuriyama, K; Miyawaki, S; Motoji, T; Nakano, Y; Naoe, T; Nishimura, M; Ohno, R; Saito, H; Saito, K; Shimazaki, C; Shinagawa, K; Suzuki, R; Takeshita, A; Ueda, R; Yagasaki, F; Yamamoto, Y | 1 |
| Hall, EJ; Hei, TK; Piao, CQ; Willey, JC; Wu, LJ | 1 |
| Al-Mulla, F; MacKenzie, EM | 1 |
| Danielsen, AJ; Maihle, NJ | 1 |
| Katze, JR | 2 |
| Jackson, RC; Morris, HP; Weber, G | 1 |
| Sanchez, J; Tlsty, TD; White, A | 1 |
| Haran, MS; Kinsella, AR | 1 |
| Cerutti, I; Chany, C; Chany-Fournier, F | 1 |
| Baikie, AG; Dartnall, JA | 1 |
| Michl, J; Rezácová, D; Svobodová, J; Vonka, V | 1 |
| Oda, KI; Sekiya, T | 1 |
| Briscoe, WT; Duff, R; Griffin, AC; Rapp, F; Taylor, W | 1 |
| Gallagher, RE; Gallo, RC; Ting, RC | 1 |
| Seaver, SS; Stark, GR; Swyryd, EA | 1 |
| Hung, PP; Kothari, RM; Taylor, MW; Wang, S | 1 |
42 other study(ies) available for aspartic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Glycine; Hematologic Neoplasms; Hematopoiesis; Hematopoietic Stem Cells; Lipoylation; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Monomeric GTP-Binding Proteins; Palmitic Acid | 2020 |
Mutation of Vav1 adaptor region reveals a new oncogenic activation.
Topics: Animals; Anthracenes; Aspartic Acid; beta Catenin; Blotting, Western; Cell Line, Tumor; Cell Transformation, Neoplastic; Fibroblasts; HEK293 Cells; Humans; MAP Kinase Kinase 4; Mice; Mice, Nude; Mutation; NIH 3T3 Cells; Phosphorylation; Protein Binding; Proto-Oncogene Mas; Proto-Oncogene Proteins c-vav; RNA Interference; Signal Transduction; src Homology Domains | 2015 |
Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Topics: Animals; Aspartic Acid; Carboxylic Acids; Carcinoma, Renal Cell; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Immunoblotting; Kidney; Kidney Neoplasms; Male; Metabolomics; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Pyruvate Carboxylase; Pyruvic Acid; RNA Interference; Succinate Dehydrogenase | 2015 |
Targeting eradication of malignant cells derived from human bone marrow mesenchymal stromal cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; Antigens, CD; Antimetabolites; Aspartic Acid; Bone Marrow Cells; Cell Differentiation; Cell Survival; Cell Transformation, Neoplastic; Cytosine Deaminase; Escherichia coli Proteins; Flucytosine; Gene Expression; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Kruppel-Like Transcription Factors; Lentivirus; Luciferases; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Phosphonoacetic Acid; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Response Elements; Stromal Cells; Telomerase; Transduction, Genetic; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays; Young Adult | 2010 |
Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Susceptibility; Epithelium; Glycine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mouth Neoplasms; Mutation, Missense; Pancreatic Neoplasms; Papilloma; Proto-Oncogene Proteins p21(ras) | 2011 |
Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.
Topics: Amino Acid Substitution; Animals; Aspartic Acid; Bone Marrow Transplantation; Cell Transformation, Neoplastic; Female; Gene Dosage; Genes, ras; Glutamic Acid; Hematologic Neoplasms; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Oncogenes; Organ Specificity | 2011 |
Overexpression of the 18 kDa and 22/24 kDa FGF-2 isoforms results in differential drug resistance and amplification potential.
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Division; Cell Transformation, Neoplastic; Clone Cells; Diffusion Chambers, Culture; Dihydroorotase; Drug Resistance; Enzyme Inhibitors; Fibroblast Growth Factor 2; Fibroblasts; Gene Amplification; Gene Expression; Immunoblotting; Mice; Molecular Weight; Phosphonoacetic Acid; Protein Isoforms; Transfection | 2002 |
Antiapoptotic Cdc42 mutants are potent activators of cellular transformation.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Apoptosis; Asparagine; Aspartic Acid; cdc42 GTP-Binding Protein; Cell Division; Cell Transformation, Neoplastic; COS Cells; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Mice; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Binding; Trans-Activators; Transfection | 2002 |
ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blotting, Northern; Bone Marrow; Cell Nucleus; Cell Transformation, Neoplastic; Conserved Sequence; DNA-Binding Proteins; Glutamic Acid; HeLa Cells; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Immunosorbent Techniques; Leukemia, Myeloid, Acute; Mice; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Oncogene Proteins, Fusion; Peptide Fragments; Proto-Oncogenes; Recombinant Fusion Proteins; Retroviridae; Sequence Homology; Serine; Transcription Factors; Transcriptional Elongation Factors; Transfection | 2003 |
12-O-tetradecanoylphorbol-13-acetate and UV radiation-induced nucleoside diphosphate protein kinase B mediates neoplastic transformation of epidermal cells.
Topics: Animals; Antigens, CD34; Arginine; Aspartic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Cloning, Molecular; Culture Media, Serum-Free; DNA, Complementary; Epidermal Cells; Epidermis; Female; Gene Dosage; Glycine; Homozygote; Humans; Immunoblotting; In Situ Hybridization; Keratinocytes; Kinetics; Mice; Mutagenesis, Site-Directed; Mutation; Nucleoside-Diphosphate Kinase; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution; Transfection; Ultraviolet Rays; Up-Regulation | 2004 |
A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Animals; Asparagine; Aspartic Acid; Binding Sites; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-met; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Tyrosine; Ubiquitin; Ubiquitin-Protein Ligases | 2004 |
A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Blotting, Western; Cell Membrane; Cell Proliferation; Cell Transformation, Neoplastic; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Immunoprecipitation; Ligands; Mice; Molecular Sequence Data; Mutation; Neovascularization, Pathologic; NIH 3T3 Cells; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Thymidine; Time Factors; Tyrosine; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2006 |
Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transplantation; Female; Humans; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Mutagenesis, Site-Directed; Point Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Transfection; Valine | 1995 |
p53 expression in normal versus transformed mammalian cells.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Aspartic Acid; Burkitt Lymphoma; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; CHO Cells; Cholera Toxin; Cricetinae; Drug Resistance; Embryo, Mammalian; Gene Expression; Genes, p53; Humans; Immunohistochemistry; L Cells; Lymphocytes; Methotrexate; Mice; Phosphonoacetic Acid; Reference Values; Theophylline; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1995 |
Accumulation of anchorage independent cells showing amplified genes (CAD) during the in vitro propagation of CHEF18 Chinese hamster cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Dihydroorotase; Drug Resistance; Gene Amplification; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Phosphonoacetic Acid; Thioguanine | 1993 |
Increased methotrexate resistance and dhfr gene amplification as a consequence of induced Ha-ras expression in NIH 3T3 cells.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Aspartic Acid; Cell Transformation, Neoplastic; Drug Resistance; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, ras; Isopropyl Thiogalactoside; Methotrexate; Mice; Phosphonoacetic Acid; Tetrahydrofolate Dehydrogenase | 1994 |
Amplification potential in preneoplastic and neoplastic Syrian hamster embryo fibroblasts transformed by various carcinogens.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; DNA, Neoplasm; Drug Resistance; Embryo, Mammalian; Fibroblasts; Fibrosarcoma; Gene Amplification; In Situ Hybridization, Fluorescence; Mesocricetus; Mice; Mice, Inbred BALB C; Mice, Nude; Oncogenes; Phosphonoacetic Acid; Precancerous Conditions; Transfection; Tumor Cells, Cultured | 1993 |
Tumorigenicity and gene amplification potentials of cyclin D1-overexpressing NIH3T3 cells.
Topics: 3T3 Cells; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Adhesion; Cell Transformation, Neoplastic; Cyclin D1; Cyclins; Dihydroorotase; Gene Amplification; Humans; Mice; Multienzyme Complexes; Neoplasms, Experimental; Oncogene Proteins; Phosphonoacetic Acid; Transfection | 1995 |
Identifying monoaminergic, GABAergic, and cholinergic characteristics in immortalized neuronal cell lines.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cerebellum; Culture Media, Serum-Free; Dopamine; gamma-Aminobutyric Acid; Genes, myc; Glutamic Acid; Hippocampus; Hybrid Cells; Mice; Neuroblastoma; Neurons; Neurotransmitter Agents; Norepinephrine; PC12 Cells; Rats; Rhombencephalon; Serotonin | 1997 |
Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cell Transformation, Neoplastic; Choline; Creatine; Deoxyglucose; Disease Progression; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Follow-Up Studies; Glioma; Humans; Hydrogen; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Phosphocreatine; Prognosis; Protons; Radiopharmaceuticals; Tomography, Emission-Computed | 1997 |
Detection of Ki-ras mutations by PCR and differential hybridization and of p53 mutations by SSCP analysis in endoscopically obtained lavage solution from patients with long-standing ulcerative colitis.
Topics: Aspartic Acid; Biopsy; Case-Control Studies; Cell Transformation, Neoplastic; Codon; Colitis, Ulcerative; Colonic Neoplasms; Colonoscopy; Digoxigenin; DNA; Exons; Female; Genes, p53; Genes, ras; Genetic Testing; Glycine; Humans; Immunoblotting; Male; Mutation; Nucleic Acid Hybridization; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Therapeutic Irrigation; Valine | 1997 |
Mapping of a serine-rich domain essential for the transcriptional, antiapoptotic, and transforming activities of the v-Rel oncoprotein.
Topics: Amino Acid Sequence; Animals; Apoptosis; Aspartic Acid; Binding Sites; Cell Transformation, Neoplastic; Chickens; COS Cells; HeLa Cells; Humans; Molecular Sequence Data; Mutagenesis; Oncogene Proteins v-rel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Retroviridae Proteins, Oncogenic; Serine; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype.
Topics: Aspartic Acid; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Phenotype; Phosphonoacetic Acid; Phosphorylation; Protein Biosynthesis; Proteins; Retinoblastoma Protein; RNA; Telomerase; Tumor Cells, Cultured | 1999 |
Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells.
Topics: Animals; Aspartic Acid; Cell Death; Cell Division; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; DNA Damage; Folic Acid Deficiency; Gene Amplification; Mice; Mice, Inbred BALB C; Phosphonoacetic Acid; Thymine Nucleotides; Uracil | 1999 |
Gene amplification and microsatellite instability induced in tumorigenic human bronchial epithelial cells by alpha particles and heavy ions.
Topics: Alpha Particles; Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Bronchi; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Transformation, Neoplastic; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 3; Dihydroorotase; Drug Resistance, Neoplasm; Epithelial Cells; Gene Amplification; Heavy Ions; Humans; Iron; Lung Neoplasms; Mice; Mice, Nude; Microsatellite Repeats; Multienzyme Complexes; Neoplasm Proteins; Neoplasms, Radiation-Induced; Phosphonoacetic Acid; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.
Topics: Acute Disease; Amino Acid Substitution; Animals; Aspartic Acid; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chlorocebus aethiops; Codon; COS Cells; DNA, Complementary; fms-Like Tyrosine Kinase 3; Hematologic Neoplasms; Humans; Leukemia, Myeloid; Mutagenesis, Site-Directed; Mutation, Missense; Myelodysplastic Syndromes; Point Mutation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Tandem Repeat Sequences; Transfection | 2001 |
Genomic instability and tumorigenic induction in immortalized human bronchial epithelial cells by heavy ions.
Topics: Alpha Particles; Animals; Antineoplastic Agents; Aspartic Acid; Bronchi; Cell Fusion; Cell Line, Transformed; Cell Transformation, Neoplastic; Epithelial Cells; Gene Amplification; Genes, Tumor Suppressor; Heavy Ions; Humans; Iron; Linear Energy Transfer; Lung Neoplasms; Mercaptoethylamines; Mice; Mice, Nude; Phosphonoacetic Acid; Radiation-Protective Agents; Tumor Cells, Cultured | 1998 |
Differences in in vitro invasive capacity induced by differences in Ki-Ras protein mutations.
Topics: Aspartic Acid; Blotting, Western; Cell Transformation, Neoplastic; Endothelial Growth Factors; Fibroblasts; Humans; Lymphokines; Mutation; Neoplasm Invasiveness; Proto-Oncogene Proteins p21(ras); Transfection; Tumor Cells, Cultured; Valine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Ligand-independent oncogenic transformation by the EGF receptor requires kinase domain catalytic activity.
Topics: Alanine; Animals; Aspartic Acid; Catalysis; Cell Line, Transformed; Cell Nucleus; Cell Transformation, Neoplastic; Chick Embryo; ErbB Receptors; Fibroblasts; Gene Expression Regulation, Neoplastic; Ligands; Mutation; Oncogene Proteins v-erbB; Protein Kinases; Protein Structure, Tertiary; Signal Transduction; Tyrosine | 2002 |
Alterations in SVT2 cell transfer RNAs in response to cell density and serum type.
Topics: Animals; Asparagine; Aspartic Acid; Cattle; Cell Line; Cell Transformation, Neoplastic; Culture Media; Cyanogen Bromide; Histidine; Mice; Mice, Inbred BALB C; RNA, Transfer; RNA, Viral; Simian virus 40; Tyrosine | 1975 |
Neoplastic transformation-linked alterations in adenylosuccinate synthetase activity.
Topics: Aging; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Inosine Nucleotides; Kidney; Kidney Neoplasms; Ligases; Liver; Liver Neoplasms; Liver Regeneration; Male; Rats | 1975 |
Relation of cell type and cell density in tissue culture to the isoaccepting spectra of the nucleoside Q containing tRNAs: tRNATyr, tRNAHis, tRNAAsn and tRNAAsp.
Topics: Asparagine; Aspartic Acid; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; Cyanogen Bromide; Guanosine; Histidine; RNA, Transfer; Simian virus 40; Tyrosine | 1978 |
Suppression of gene amplification in human cell hybrids.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Cell Line; Cell Transformation, Neoplastic; Drug Resistance; Gene Amplification; Gene Expression Regulation, Enzymologic; Genes, Dominant; Genes, Recessive; Humans; Hybrid Cells; Mutation; Phenotype; Phosphonoacetic Acid; Suppression, Genetic; Tumor Cells, Cultured | 1992 |
Decreasing sensitivity to cytotoxic agents parallels increasing tumorigenicity in human fibroblasts.
Topics: Aspartic Acid; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Resistance; Fibroblasts; Gene Amplification; Humans; Methotrexate; Phenotype; Phosphonoacetic Acid | 1991 |
[Experimental biotherapy of malignant tumors. Trial therapeutic application].
Topics: Animals; Aspartic Acid; Butyrates; Cell Transformation, Neoplastic; Immunotherapy; Interferons; Mice; Neoplasms, Experimental | 1986 |
L-asparaginase and blastogenesis.
Topics: Asparaginase; Asparagine; Aspartic Acid; Cell Differentiation; Cell Transformation, Neoplastic; Culture Media; Culture Techniques; Humans; Lymphocytes; Mitosis | 1969 |
Transcarbamylase activity and Na2H32PO4 transport in mammalian cells in culture.
Topics: Animals; Aspartic Acid; Biological Transport; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; Cricetinae; Culture Techniques; Diploidy; HeLa Cells; Humans; L Cells; Mice; Neoplasms, Experimental; Phosphates; Phosphorus Isotopes; Simian virus 40; Transferases | 1969 |
The altered patterns of transfer RNA in SV40-infected and transformed cells.
Topics: Acylation; Amino Acids; Amino Acyl-tRNA Synthetases; Ammonium Sulfate; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; DNA, Viral; Electron Transport; Haplorhini; Histidine; Kidney; Nucleic Acid Hybridization; Ribosomes; RNA, Transfer; Simian virus 40; Tritium | 1972 |
Aspartyl transfer RNA profiles in normal and cancer cells.
Topics: Animals; Ascites; Aspartic Acid; Breast Neoplasms; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Transformation, Neoplastic; Chromatography; Chromatography, DEAE-Cellulose; Cricetinae; Humans; Liver; Liver Neoplasms; Methods; Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred Strains; RNA, Transfer; Simian virus 40; Tritium | 1972 |
A common change of aspartyl-tRNA in polyoma- and SV40 -transformed cells.
Topics: Amino Acyl-tRNA Synthetases; Animals; Aspartic Acid; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Chromatography; Chromatography, Gel; Embryo, Mammalian; Fibroblasts; Fibrosarcoma; Liver; Mice; Moloney murine leukemia virus; Neoplasms, Experimental; Phenylalanine; Polyomavirus; Rats; RNA, Transfer; RNA, Viral; Simian virus 40; Tritium | 1972 |
N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotopes; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Ion Exchange; Fibroblasts; Haplorhini; Kidney; Kinetics; Mice; Mice, Inbred Strains; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Simian virus 40; Species Specificity; Time Factors; Tritium; Uridine | 1974 |
Chromatographic analyses of isoaccepting tRNAs from avian tumor viruses.
Topics: Alpharetrovirus; Amino Acyl-tRNA Synthetases; Animals; Arginine; Aspartic Acid; Avian Sarcoma Viruses; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cell-Free System; Chick Embryo; Chickens; Chromatography; Culture Techniques; Fibroblasts; Liver; Lysine; Methionine; RNA, Neoplasm; RNA, Transfer; RNA, Viral; Satellite Viruses; Tritium | 1974 |