Page last updated: 2024-08-17

aspartic acid and Cataract, Membranous

aspartic acid has been researched along with Cataract, Membranous in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199012 (28.57)18.7374
1990's7 (16.67)18.2507
2000's6 (14.29)29.6817
2010's14 (33.33)24.3611
2020's3 (7.14)2.80

Authors

AuthorsStudies
Fujii, N; Ha, S; Kinouchi, T1
Fujii, N; Hachiya, N; Magami, K; Morikawa, K; Takata, T1
He, WW; Lu, Y; Qi, J; Zhang, KK; Zhu, XJ1
Breck, O; Hevrøy, EM; Olsvik, PA; Remø, SC; Waagbø, R1
Du, Y; He, WW; Hooi, M; Lu, Y; Zhang, KK; Zhu, XJ1
Fujii, N; Ha, S; Isoyama, M; Kim, I; Kinouchi, T; Suzuki, M; Takata, T1
Fujii, N; Matsubara, T; Nakamura-Hirota, T; Takata, T1
Jin, H; Jin, J; Liu, X; Zhu, B; Zou, H1
Garringer, HJ; Ghetti, B; Gnezda, A; Murrell, J; Sammeta, N; Vidal, R1
Wang, H; Wu, D; Zhang, J; Zhang, T1
Fujii, N; Maeda, H; Nirasawa, S; Sakaue, H; Sasaki, H; Takahashi, S; Takata, T1
Aki, K; Fujii, N; Takata, T1
Fujii, N; Takata, T1
Fu, Y; Jia, X; Liu, G; Lu, X; Wang, X; Xing, B; Yang, G; Yu, H; Zhao, J1
Lu, Y; Luo, Y; Wang, L; Wen, W; Zhang, S1
Fujii, N; Sakaue, H; Sasaki, H1
Hooi, MY; Raftery, MJ; Truscott, RJ1
Fujii, N; Kamei, A; Kuge, K; Saito, T; Takata, T; Takeuchi, N; Tezuka, T1
Addison, PK; Berry, V; Bhattacharya, SS; Espinal, D; Holden, KR; Rivera, B; Srivastava, AK; Su, H1
Engel, W; Graw, J; Illig, T; Klopp, N; Pauli, S; Söker, T1
Fujii, S; Oishi, M; Takahashi, K1
Masters, PM1
Kodama, T; Mizobuchi, M; Ohashi, Y; Shinomiya, H; Takeda, R; Torikai, H1
Carter, DA; McFadden, PN1
Ala-Kokko, L; Haataja, L; Kääriäinen, H; Kivirikko, KI; Körkkö, J; Prockop, DJ; Ritvaniemi, P1
Cheng, CL; Lee, SM; Liang, RC; Lin, SY1
Akaboshi, M; Boyle, D; Fujii, N; Hiroki, K; Matsumoto, S; Takemoto, LJ1
Boyle, D; Fujii, N; Takemoto, L1
Fujii, N; Hiroki, K; Matsumoto, S; Takemoto, L1
Heinitz, M1
Bada, JL; Masters, PM; Zigler, JS2
Garner, WH; Spector, A1
Cupak, K; Kosanović, M1
Emmons, T; Granstrom, D; Takemoto, L1
D'Aniello, A; D'Onofrio, G; Pischetola, M1
Hoenders, HJ; van den Oetelaar, PJ1
Fujii, N; Harada, K; Joshima, H; Kashima, M; Tamanoi, I1
Baron, WS1
Andersen, AE; Guroff, G; Rowe, VD; Sidbury, JB; Zigler, S1
Gruber, L; Harris, JE1
Carta, F; Maraini, G; Pescatori, A; Prosperi, L1

Reviews

1 review(s) available for aspartic acid and Cataract, Membranous

ArticleYear
Isomerization of aspartyl residues in crystallins and its influence upon cataract.
    Biochimica et biophysica acta, 2016, Volume: 1860, Issue:1 Pt B

    Topics: Aging; Amino Acid Sequence; Animals; Aspartic Acid; Cataract; Crystallins; Humans; Isomerism; Lens, Crystalline; Molecular Sequence Data; Structure-Activity Relationship

2016

Other Studies

41 other study(ies) available for aspartic acid and Cataract, Membranous

ArticleYear
Age-related isomerization of Asp in human immunoglobulin G kappa chain.
    Biochimica et biophysica acta. Proteins and proteomics, 2020, Volume: 1868, Issue:6

    Topics: Adult; Aged; Aging; Aspartic Acid; Biomarkers; Cataract; Chromatography, Liquid; Humans; Immunoglobulin G; Immunoglobulin kappa-Chains; Immunologic Factors; Isomerism; Middle Aged; Models, Molecular; Peptides; Protein Processing, Post-Translational; Proteome; Serum; Stereoisomerism; Tandem Mass Spectrometry

2020
Isomerization of Asp is essential for assembly of amyloid-like fibrils of αA-crystallin-derived peptide.
    PloS one, 2021, Volume: 16, Issue:4

    Topics: Aging; Alanine; alpha-Crystallin A Chain; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Aspartic Acid; Benzothiazoles; Cataract; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Isoaspartic Acid; Isomerism; Lens, Crystalline; Microscopy, Electron; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Processing, Post-Translational; Static Electricity

2021
Racemization in cataractous lens from diabetic and aging individuals: analysis of Asp 58 residue in αA-crystallin.
    Aging, 2021, 06-07, Volume: 13, Issue:11

    Topics: Aged; Aging; Aspartic Acid; Cataract; Cell Nucleus; Crystallins; Female; Humans; Isomerism; Lens, Crystalline; Male; Solubility

2021
Lens metabolomic profiling as a tool to understand cataractogenesis in Atlantic salmon and rainbow trout reared at optimum and high temperature.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Amino Acids; Animals; Aspartic Acid; Carbohydrate Metabolism; Cataract; Fish Diseases; Glutathione; Histidine; Homeostasis; Hot Temperature; Lens, Crystalline; Metabolomics; Oncorhynchus mykiss; Osmoregulation; Oxidation-Reduction; Salmo salar; Seawater; Severity of Illness Index; Species Specificity; Temperature

2017
Racemization at the Asp 58 residue in αA-crystallin from the lens of high myopic cataract patients.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:2

    Topics: Aged; Aspartic Acid; Cataract; Crystallins; Female; Humans; Lens, Crystalline; Male; Myopia; Stereoisomerism

2018
Identification of ᴅ-amino acid-containing peptides in human serum.
    PloS one, 2017, Volume: 12, Issue:12

    Topics: Adult; Alzheimer Disease; Amino Acids; Aspartic Acid; Biomarkers; Cataract; Chromatography, Liquid; Crystallins; Fibrinogen; Fibrinopeptide B; Humans; Middle Aged; Peptides; Proteomics; Tandem Mass Spectrometry; Young Adult

2017
Negative charge at aspartate 151 is important for human lens αA-crystallin stability and chaperone function.
    Experimental eye research, 2019, Volume: 182

    Topics: Aged; Aged, 80 and over; alpha-Crystallin A Chain; Aspartic Acid; Cataract; Chromatography, High Pressure Liquid; DNA; DNA Mutational Analysis; Humans; Lens, Crystalline; Middle Aged; Molecular Chaperones; Mutation; Protein Folding

2019
Metabolic characterization of diabetic retinopathy: An
    Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174

    Topics: Aged; Alanine; Antioxidants; Aqueous Humor; Area Under Curve; Aspartic Acid; Cataract; Diabetic Retinopathy; Female; Glutamic Acid; Humans; Male; Metabolomics; Middle Aged; Prospective Studies; Proton Magnetic Resonance Spectroscopy

2019
Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Cataract; Cerebellar Ataxia; Deafness; Dementia; Female; Gene Expression; Hippocampus; Humans; Immunohistochemistry; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neocortex; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Synaptophysin; tau Proteins

2013
A novel beaded filament structural protein 1 (BFSP1) gene mutation associated with autosomal dominant congenital cataract in a Chinese family.
    Molecular vision, 2013, Volume: 19

    Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Animals; Asian People; Asparagine; Aspartic Acid; Case-Control Studies; Cataract; Exons; Eye Proteins; Female; Genetic Linkage; Genotype; Humans; Intermediate Filament Proteins; Lens, Crystalline; Male; Molecular Sequence Data; Mutation, Missense; Pedigree; Sequence Alignment; Sequence Analysis, DNA

2013
Rapid survey of four Asp isomers in disease-related proteins by LC-MS combined with commercial enzymes.
    Analytical chemistry, 2015, Jan-06, Volume: 87, Issue:1

    Topics: Aged, 80 and over; Aspartic Acid; Cataract; Chromatography, Liquid; Crystallins; Humans; Lens, Crystalline; Stereoisomerism; Tandem Mass Spectrometry

2015
Isomerization of Asp residues plays an important role in αA-crystallin dissociation.
    The FEBS journal, 2016, Volume: 283, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; alpha-Crystallin A Chain; Aspartic Acid; Cataract; Chromatography; Chromatography, Liquid; Humans; Isomerism; Lens, Crystalline; Middle Aged; Polymers; Protein Binding; Protein Processing, Post-Translational; Tandem Mass Spectrometry; Trypsin

2016
A novel mutation in the GJA3 (connexin46) gene is associated with autosomal dominant congenital nuclear cataract in a Chinese family.
    Molecular vision, 2011, Apr-27, Volume: 17

    Topics: Amino Acid Sequence; Asian People; Asparagine; Aspartic Acid; Base Sequence; Cataract; Chromosomes, Human, Pair 13; Connexins; Female; Genes, Dominant; Genetic Linkage; Genotype; Haplotypes; Humans; Lens, Crystalline; Lod Score; Male; Microsatellite Repeats; Molecular Sequence Data; Mutation, Missense; Pedigree

2011
Another evidence for a D47N mutation in GJA8 associated with autosomal dominant congenital cataract.
    Molecular vision, 2011, Volume: 17

    Topics: Asian People; Asparagine; Aspartic Acid; Case-Control Studies; Cataract; Connexin 26; Connexins; DNA Mutational Analysis; Exons; Eye Proteins; Female; Genes, Dominant; Genetic Linkage; Humans; Male; Models, Molecular; Mutant Proteins; Mutation, Missense; Pedigree; Polymerase Chain Reaction; Thermodynamics

2011
A rapid, comprehensive liquid chromatography-mass spectrometry (LC-MS)-based survey of the Asp isomers in crystallins from human cataract lenses.
    The Journal of biological chemistry, 2012, Nov-16, Volume: 287, Issue:47

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Cataract; Chromatography, Liquid; Crystallins; Female; Humans; Lens, Crystalline; Male; Mass Spectrometry; Middle Aged; Protein Processing, Post-Translational; Solubility; Stereoisomerism

2012
Accelerated aging of Asp 58 in αA crystallin and human cataract formation.
    Experimental eye research, 2013, Volume: 106

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; alpha-Crystallin A Chain; Aspartic Acid; Cataract; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Infant, Newborn; Isoaspartic Acid; Lens, Crystalline; Middle Aged; Peptide Fragments; Racemases and Epimerases; Spectrometry, Mass, Electrospray Ionization; Young Adult

2013
Comparison of post-translational modifications of alpha A-crystallin from normal and hereditary cataract rats.
    Amino acids, 2004, Volume: 26, Issue:2

    Topics: Aging; alpha-Crystallin A Chain; Animals; Aspartic Acid; Cataract; Disease Models, Animal; Humans; Isomerism; Lens, Crystalline; Methionine; Molecular Structure; Oxidation-Reduction; Peptides; Protein Processing, Post-Translational; Rats; Rats, Mutant Strains; Rats, Wistar; Time Factors

2004
A novel mutation in the connexin 46 gene (GJA3) causes autosomal dominant zonular pulverulent cataract in a Hispanic family.
    Molecular vision, 2006, Jul-20, Volume: 12

    Topics: Aspartic Acid; Cataract; Chromosome Mapping; Connexins; Female; Genes, Dominant; Genetic Linkage; Guanine; Haplotypes; Heterozygote; Hispanic or Latino; Honduras; Humans; Lod Score; Male; Mutation, Missense; Pedigree; Thymine; Tyrosine

2006
Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene.
    Molecular vision, 2007, Jun-19, Volume: 13

    Topics: Alleles; Amino Acid Sequence; Aspartic Acid; Base Sequence; beta-Crystallin B Chain; Cataract; Child, Preschool; DNA Mutational Analysis; Female; Germany; Humans; Infant, Newborn; Male; Molecular Biology; Molecular Sequence Data; Mutation; Pedigree; Proteomics; Valine

2007
[An eye-lotion of aspartate upon senile cataract].
    Nihon ganka kiyo, 1966, Volume: 17, Issue:8

    Topics: Adult; Aged; Aspartic Acid; Cataract; Female; Humans; Male; Middle Aged; Ophthalmic Solutions

1966
Senile cataracts and aging changes in human proteins.
    Journal of the American Geriatrics Society, 1983, Volume: 31, Issue:7

    Topics: Aged; Aging; Aspartic Acid; Cataract; Crystallins; Humans; In Vitro Techniques; Molecular Weight; Protein Conformation; Proteins

1983
Hampered expression of isoaspartyl protein carboxyl methyltransferase gene in the human cataractous lens.
    Biochimica et biophysica acta, 1995, Oct-19, Volume: 1245, Issue:2

    Topics: Aspartic Acid; Base Sequence; Blotting, Northern; Cataract; Epithelium; Gene Expression; Humans; Lens, Crystalline; Molecular Sequence Data; Polymerase Chain Reaction; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; RNA-Directed DNA Polymerase; RNA, Messenger

1995
Determination of beta-isomerized aspartic acid as the corresponding alcohol.
    Journal of protein chemistry, 1994, Volume: 13, Issue:1

    Topics: Aluminum Compounds; Amino Acids; Asparagine; Aspartic Acid; Boranes; Cataract; Chymotrypsin; Crystallins; Homoserine; Humans; Indicators and Reagents; Isomerism; Lithium Compounds; Ovalbumin; Proteins; Succinimides; Tetragastrin

1994
Mutation in type II procollagen (COL2A1) that substitutes aspartate for glycine alpha 1-67 and that causes cataracts and retinal detachment: evidence for molecular heterogeneity in the Wagner syndrome and the Stickler syndrome (arthro-ophthalmopathy)
    American journal of human genetics, 1993, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Amino Acid Sequence; Aspartic Acid; Base Sequence; Cataract; Child; Child, Preschool; DNA; DNA Mutational Analysis; Female; Glycine; Humans; Joint Diseases; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Procollagen; Retinal Detachment; Syndrome

1993
Possible changes in secondary structure and composition of human lens capsules in hereditary congenital cataract.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1996, Volume: 234, Issue:5

    Topics: Adult; Aspartic Acid; Cataract; Crystallins; Female; Fourier Analysis; Humans; Hydroxylysine; Lens Capsule, Crystalline; Protein Conformation; Protein Structure, Secondary; Spectrophotometry, Infrared

1996
Comparison of d-aspartic acid contents in alpha A-crystallin from normal and age-matched cataractous human lenses.
    Biochemical and biophysical research communications, 2000, Nov-19, Volume: 278, Issue:2

    Topics: Amino Acid Sequence; Aspartic Acid; Case-Control Studies; Cataract; Chromatography, High Pressure Liquid; Crystallins; Humans; Lens, Crystalline; Middle Aged

2000
Mechanism of asparagine deamidation during human senile cataractogenesis.
    Experimental eye research, 2001, Volume: 72, Issue:5

    Topics: Asparagine; Aspartic Acid; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Humans; Succinimides

2001
Inversion and isomerization of Asp-58 residue in human alphaA-crystallin from normal aged lenses and cataractous lenses.
    Biochimica et biophysica acta, 2001, Oct-18, Volume: 1549, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Cataract; Crystallins; Humans; Infant; Isomerism; Lens, Crystalline; Middle Aged; Models, Chemical; Protein Folding; Stereoisomerism

2001
[Clinical biochemical aspects of the prophylaxis and therapy of senile cataract with zinc aspartate (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1978, Volume: 172, Issue:5

    Topics: Age Factors; Aged; Aspartic Acid; Cataract; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehydrogenase; Glycolysis; Hexokinase; Humans; L-Lactate Dehydrogenase; Lens, Crystalline; Long-Term Care; Malate Dehydrogenase; Zinc

1978
Aspartic acid racemization in heavy molecular weight crystallins and water insoluble protein from normal human lenses and cataracts.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Cataract; Child; Child, Preschool; Crystallins; Humans; Infant; Infant, Newborn; Lens, Crystalline; Middle Aged; Molecular Weight; Protein Conformation; Solubility; Stereoisomerism

1978
Racemization in human lens: evidence of rapid insolubilization of specific polypeptides in cataract formation.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:8

    Topics: Age Factors; Aspartic Acid; Cataract; Crystallins; Humans; Isomerism; Lens, Crystalline; Peptides; Solubility

1978
Aspartic acid racemisation in the human lens during ageing and in cataract formation.
    Nature, 1977, Jul-07, Volume: 268, Issue:5615

    Topics: Aging; Aspartic Acid; Cataract; Humans; Lens, Crystalline; Stereoisomerism

1977
Contemporary possibilities of medicamentous prevention of cataract.
    Acta medica Iugoslavica, 1990, Volume: 44, Issue:4

    Topics: Adult; Aged; Aspartic Acid; Cataract; Drug Combinations; Female; Humans; Indazoles; Inosine Monophosphate; Male; Middle Aged; Niacinamide; Parabens; Thimerosal; Visual Acuity

1990
The sequences of two peptides from cataract lenses suggest they arise by deamidation.
    Current eye research, 1990, Volume: 9, Issue:8

    Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cataract; Cattle; Crystallins; Deamination; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptide Fragments; Peptides; Rabbits; Radioimmunoassay; Sequence Homology, Nucleic Acid; Trypsin

1990
Total hydrolysis of proteins with strongly reduced racemization of amino acids.
    Biochimica et biophysica acta, 1990, Feb-09, Volume: 1037, Issue:2

    Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Cataract; Female; Humans; Hydrolysis; Lens, Crystalline; Leucyl Aminopeptidase; Male; Middle Aged; Peptides; Pronase; Proteins; Spectrophotometry, Ultraviolet; Temperature

1990
Racemization of aspartyl residues in proteins from normal and cataractous human lenses: an aging process without involvement in cataract formation.
    Experimental eye research, 1989, Volume: 48, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Cataract; Crystallins; Humans; Isomerism; Lens, Crystalline; Middle Aged

1989
D-amino acid in irradiated and aged mouse.
    Journal of radiation research, 1986, Volume: 27, Issue:2

    Topics: Aging; Amino Acids; Animals; Aspartic Acid; Cataract; Crystallins; Male; Mice; Mice, Inbred Strains; Molecular Conformation; Skin; Whole-Body Irradiation

1986
Lenticular and fundus changes induced by the intraocular infusion of sodium aspartate.
    Investigative ophthalmology, 1974, Volume: 13, Issue:6

    Topics: Animals; Aspartic Acid; Cataract; Fundus Oculi; Haplorhini; Injections; Intraocular Pressure; Lens, Crystalline; Macaca; Ophthalmoscopy; Retina; Retinal Vessels; Sodium; Vitreous Body

1974
Some characteristics of the p-chlorophenylalanine-induced cataract.
    Experimental eye research, 1973, Nov-11, Volume: 17, Issue:3

    Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Cataract; Chromatography, Gas; Crystallins; Electrophoresis; Female; Fenclonine; Glutathione; Glycine; Lens, Crystalline; Male; Ornithine; Rats; Serine; Threonine

1973
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
    Investigative ophthalmology, 1973, Volume: 12, Issue:5

    Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine

1973
Protein metabolism in human senile cataract.
    Experimental eye research, 1971, Volume: 11, Issue:1

    Topics: Adenosine Triphosphate; Aged; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Cataract; Crystallins; Guanosine Triphosphate; Humans; Lens, Crystalline; Leucine; Rabbits; Tritium

1971