aspartic acid has been researched along with Cataract, Membranous in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (28.57) | 18.7374 |
1990's | 7 (16.67) | 18.2507 |
2000's | 6 (14.29) | 29.6817 |
2010's | 14 (33.33) | 24.3611 |
2020's | 3 (7.14) | 2.80 |
Authors | Studies |
---|---|
Fujii, N; Ha, S; Kinouchi, T | 1 |
Fujii, N; Hachiya, N; Magami, K; Morikawa, K; Takata, T | 1 |
He, WW; Lu, Y; Qi, J; Zhang, KK; Zhu, XJ | 1 |
Breck, O; Hevrøy, EM; Olsvik, PA; Remø, SC; Waagbø, R | 1 |
Du, Y; He, WW; Hooi, M; Lu, Y; Zhang, KK; Zhu, XJ | 1 |
Fujii, N; Ha, S; Isoyama, M; Kim, I; Kinouchi, T; Suzuki, M; Takata, T | 1 |
Fujii, N; Matsubara, T; Nakamura-Hirota, T; Takata, T | 1 |
Jin, H; Jin, J; Liu, X; Zhu, B; Zou, H | 1 |
Garringer, HJ; Ghetti, B; Gnezda, A; Murrell, J; Sammeta, N; Vidal, R | 1 |
Wang, H; Wu, D; Zhang, J; Zhang, T | 1 |
Fujii, N; Maeda, H; Nirasawa, S; Sakaue, H; Sasaki, H; Takahashi, S; Takata, T | 1 |
Aki, K; Fujii, N; Takata, T | 1 |
Fujii, N; Takata, T | 1 |
Fu, Y; Jia, X; Liu, G; Lu, X; Wang, X; Xing, B; Yang, G; Yu, H; Zhao, J | 1 |
Lu, Y; Luo, Y; Wang, L; Wen, W; Zhang, S | 1 |
Fujii, N; Sakaue, H; Sasaki, H | 1 |
Hooi, MY; Raftery, MJ; Truscott, RJ | 1 |
Fujii, N; Kamei, A; Kuge, K; Saito, T; Takata, T; Takeuchi, N; Tezuka, T | 1 |
Addison, PK; Berry, V; Bhattacharya, SS; Espinal, D; Holden, KR; Rivera, B; Srivastava, AK; Su, H | 1 |
Engel, W; Graw, J; Illig, T; Klopp, N; Pauli, S; Söker, T | 1 |
Fujii, S; Oishi, M; Takahashi, K | 1 |
Masters, PM | 1 |
Kodama, T; Mizobuchi, M; Ohashi, Y; Shinomiya, H; Takeda, R; Torikai, H | 1 |
Carter, DA; McFadden, PN | 1 |
Ala-Kokko, L; Haataja, L; Kääriäinen, H; Kivirikko, KI; Körkkö, J; Prockop, DJ; Ritvaniemi, P | 1 |
Cheng, CL; Lee, SM; Liang, RC; Lin, SY | 1 |
Akaboshi, M; Boyle, D; Fujii, N; Hiroki, K; Matsumoto, S; Takemoto, LJ | 1 |
Boyle, D; Fujii, N; Takemoto, L | 1 |
Fujii, N; Hiroki, K; Matsumoto, S; Takemoto, L | 1 |
Heinitz, M | 1 |
Bada, JL; Masters, PM; Zigler, JS | 2 |
Garner, WH; Spector, A | 1 |
Cupak, K; Kosanović, M | 1 |
Emmons, T; Granstrom, D; Takemoto, L | 1 |
D'Aniello, A; D'Onofrio, G; Pischetola, M | 1 |
Hoenders, HJ; van den Oetelaar, PJ | 1 |
Fujii, N; Harada, K; Joshima, H; Kashima, M; Tamanoi, I | 1 |
Baron, WS | 1 |
Andersen, AE; Guroff, G; Rowe, VD; Sidbury, JB; Zigler, S | 1 |
Gruber, L; Harris, JE | 1 |
Carta, F; Maraini, G; Pescatori, A; Prosperi, L | 1 |
1 review(s) available for aspartic acid and Cataract, Membranous
Article | Year |
---|---|
Isomerization of aspartyl residues in crystallins and its influence upon cataract.
Topics: Aging; Amino Acid Sequence; Animals; Aspartic Acid; Cataract; Crystallins; Humans; Isomerism; Lens, Crystalline; Molecular Sequence Data; Structure-Activity Relationship | 2016 |
41 other study(ies) available for aspartic acid and Cataract, Membranous
Article | Year |
---|---|
Age-related isomerization of Asp in human immunoglobulin G kappa chain.
Topics: Adult; Aged; Aging; Aspartic Acid; Biomarkers; Cataract; Chromatography, Liquid; Humans; Immunoglobulin G; Immunoglobulin kappa-Chains; Immunologic Factors; Isomerism; Middle Aged; Models, Molecular; Peptides; Protein Processing, Post-Translational; Proteome; Serum; Stereoisomerism; Tandem Mass Spectrometry | 2020 |
Isomerization of Asp is essential for assembly of amyloid-like fibrils of αA-crystallin-derived peptide.
Topics: Aging; Alanine; alpha-Crystallin A Chain; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Aspartic Acid; Benzothiazoles; Cataract; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Isoaspartic Acid; Isomerism; Lens, Crystalline; Microscopy, Electron; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Processing, Post-Translational; Static Electricity | 2021 |
Racemization in cataractous lens from diabetic and aging individuals: analysis of Asp 58 residue in αA-crystallin.
Topics: Aged; Aging; Aspartic Acid; Cataract; Cell Nucleus; Crystallins; Female; Humans; Isomerism; Lens, Crystalline; Male; Solubility | 2021 |
Lens metabolomic profiling as a tool to understand cataractogenesis in Atlantic salmon and rainbow trout reared at optimum and high temperature.
Topics: Amino Acids; Animals; Aspartic Acid; Carbohydrate Metabolism; Cataract; Fish Diseases; Glutathione; Histidine; Homeostasis; Hot Temperature; Lens, Crystalline; Metabolomics; Oncorhynchus mykiss; Osmoregulation; Oxidation-Reduction; Salmo salar; Seawater; Severity of Illness Index; Species Specificity; Temperature | 2017 |
Racemization at the Asp 58 residue in αA-crystallin from the lens of high myopic cataract patients.
Topics: Aged; Aspartic Acid; Cataract; Crystallins; Female; Humans; Lens, Crystalline; Male; Myopia; Stereoisomerism | 2018 |
Identification of ᴅ-amino acid-containing peptides in human serum.
Topics: Adult; Alzheimer Disease; Amino Acids; Aspartic Acid; Biomarkers; Cataract; Chromatography, Liquid; Crystallins; Fibrinogen; Fibrinopeptide B; Humans; Middle Aged; Peptides; Proteomics; Tandem Mass Spectrometry; Young Adult | 2017 |
Negative charge at aspartate 151 is important for human lens αA-crystallin stability and chaperone function.
Topics: Aged; Aged, 80 and over; alpha-Crystallin A Chain; Aspartic Acid; Cataract; Chromatography, High Pressure Liquid; DNA; DNA Mutational Analysis; Humans; Lens, Crystalline; Middle Aged; Molecular Chaperones; Mutation; Protein Folding | 2019 |
Metabolic characterization of diabetic retinopathy: An
Topics: Aged; Alanine; Antioxidants; Aqueous Humor; Area Under Curve; Aspartic Acid; Cataract; Diabetic Retinopathy; Female; Glutamic Acid; Humans; Male; Metabolomics; Middle Aged; Prospective Studies; Proton Magnetic Resonance Spectroscopy | 2019 |
Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Cataract; Cerebellar Ataxia; Deafness; Dementia; Female; Gene Expression; Hippocampus; Humans; Immunohistochemistry; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neocortex; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Synaptophysin; tau Proteins | 2013 |
A novel beaded filament structural protein 1 (BFSP1) gene mutation associated with autosomal dominant congenital cataract in a Chinese family.
Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Animals; Asian People; Asparagine; Aspartic Acid; Case-Control Studies; Cataract; Exons; Eye Proteins; Female; Genetic Linkage; Genotype; Humans; Intermediate Filament Proteins; Lens, Crystalline; Male; Molecular Sequence Data; Mutation, Missense; Pedigree; Sequence Alignment; Sequence Analysis, DNA | 2013 |
Rapid survey of four Asp isomers in disease-related proteins by LC-MS combined with commercial enzymes.
Topics: Aged, 80 and over; Aspartic Acid; Cataract; Chromatography, Liquid; Crystallins; Humans; Lens, Crystalline; Stereoisomerism; Tandem Mass Spectrometry | 2015 |
Isomerization of Asp residues plays an important role in αA-crystallin dissociation.
Topics: Adult; Aged; Aged, 80 and over; Aging; alpha-Crystallin A Chain; Aspartic Acid; Cataract; Chromatography; Chromatography, Liquid; Humans; Isomerism; Lens, Crystalline; Middle Aged; Polymers; Protein Binding; Protein Processing, Post-Translational; Tandem Mass Spectrometry; Trypsin | 2016 |
A novel mutation in the GJA3 (connexin46) gene is associated with autosomal dominant congenital nuclear cataract in a Chinese family.
Topics: Amino Acid Sequence; Asian People; Asparagine; Aspartic Acid; Base Sequence; Cataract; Chromosomes, Human, Pair 13; Connexins; Female; Genes, Dominant; Genetic Linkage; Genotype; Haplotypes; Humans; Lens, Crystalline; Lod Score; Male; Microsatellite Repeats; Molecular Sequence Data; Mutation, Missense; Pedigree | 2011 |
Another evidence for a D47N mutation in GJA8 associated with autosomal dominant congenital cataract.
Topics: Asian People; Asparagine; Aspartic Acid; Case-Control Studies; Cataract; Connexin 26; Connexins; DNA Mutational Analysis; Exons; Eye Proteins; Female; Genes, Dominant; Genetic Linkage; Humans; Male; Models, Molecular; Mutant Proteins; Mutation, Missense; Pedigree; Polymerase Chain Reaction; Thermodynamics | 2011 |
A rapid, comprehensive liquid chromatography-mass spectrometry (LC-MS)-based survey of the Asp isomers in crystallins from human cataract lenses.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Cataract; Chromatography, Liquid; Crystallins; Female; Humans; Lens, Crystalline; Male; Mass Spectrometry; Middle Aged; Protein Processing, Post-Translational; Solubility; Stereoisomerism | 2012 |
Accelerated aging of Asp 58 in αA crystallin and human cataract formation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; alpha-Crystallin A Chain; Aspartic Acid; Cataract; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Infant, Newborn; Isoaspartic Acid; Lens, Crystalline; Middle Aged; Peptide Fragments; Racemases and Epimerases; Spectrometry, Mass, Electrospray Ionization; Young Adult | 2013 |
Comparison of post-translational modifications of alpha A-crystallin from normal and hereditary cataract rats.
Topics: Aging; alpha-Crystallin A Chain; Animals; Aspartic Acid; Cataract; Disease Models, Animal; Humans; Isomerism; Lens, Crystalline; Methionine; Molecular Structure; Oxidation-Reduction; Peptides; Protein Processing, Post-Translational; Rats; Rats, Mutant Strains; Rats, Wistar; Time Factors | 2004 |
A novel mutation in the connexin 46 gene (GJA3) causes autosomal dominant zonular pulverulent cataract in a Hispanic family.
Topics: Aspartic Acid; Cataract; Chromosome Mapping; Connexins; Female; Genes, Dominant; Genetic Linkage; Guanine; Haplotypes; Heterozygote; Hispanic or Latino; Honduras; Humans; Lod Score; Male; Mutation, Missense; Pedigree; Thymine; Tyrosine | 2006 |
Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene.
Topics: Alleles; Amino Acid Sequence; Aspartic Acid; Base Sequence; beta-Crystallin B Chain; Cataract; Child, Preschool; DNA Mutational Analysis; Female; Germany; Humans; Infant, Newborn; Male; Molecular Biology; Molecular Sequence Data; Mutation; Pedigree; Proteomics; Valine | 2007 |
[An eye-lotion of aspartate upon senile cataract].
Topics: Adult; Aged; Aspartic Acid; Cataract; Female; Humans; Male; Middle Aged; Ophthalmic Solutions | 1966 |
Senile cataracts and aging changes in human proteins.
Topics: Aged; Aging; Aspartic Acid; Cataract; Crystallins; Humans; In Vitro Techniques; Molecular Weight; Protein Conformation; Proteins | 1983 |
Hampered expression of isoaspartyl protein carboxyl methyltransferase gene in the human cataractous lens.
Topics: Aspartic Acid; Base Sequence; Blotting, Northern; Cataract; Epithelium; Gene Expression; Humans; Lens, Crystalline; Molecular Sequence Data; Polymerase Chain Reaction; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; RNA-Directed DNA Polymerase; RNA, Messenger | 1995 |
Determination of beta-isomerized aspartic acid as the corresponding alcohol.
Topics: Aluminum Compounds; Amino Acids; Asparagine; Aspartic Acid; Boranes; Cataract; Chymotrypsin; Crystallins; Homoserine; Humans; Indicators and Reagents; Isomerism; Lithium Compounds; Ovalbumin; Proteins; Succinimides; Tetragastrin | 1994 |
Mutation in type II procollagen (COL2A1) that substitutes aspartate for glycine alpha 1-67 and that causes cataracts and retinal detachment: evidence for molecular heterogeneity in the Wagner syndrome and the Stickler syndrome (arthro-ophthalmopathy)
Topics: Adolescent; Adult; Amino Acid Sequence; Aspartic Acid; Base Sequence; Cataract; Child; Child, Preschool; DNA; DNA Mutational Analysis; Female; Glycine; Humans; Joint Diseases; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Procollagen; Retinal Detachment; Syndrome | 1993 |
Possible changes in secondary structure and composition of human lens capsules in hereditary congenital cataract.
Topics: Adult; Aspartic Acid; Cataract; Crystallins; Female; Fourier Analysis; Humans; Hydroxylysine; Lens Capsule, Crystalline; Protein Conformation; Protein Structure, Secondary; Spectrophotometry, Infrared | 1996 |
Comparison of d-aspartic acid contents in alpha A-crystallin from normal and age-matched cataractous human lenses.
Topics: Amino Acid Sequence; Aspartic Acid; Case-Control Studies; Cataract; Chromatography, High Pressure Liquid; Crystallins; Humans; Lens, Crystalline; Middle Aged | 2000 |
Mechanism of asparagine deamidation during human senile cataractogenesis.
Topics: Asparagine; Aspartic Acid; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Humans; Succinimides | 2001 |
Inversion and isomerization of Asp-58 residue in human alphaA-crystallin from normal aged lenses and cataractous lenses.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Cataract; Crystallins; Humans; Infant; Isomerism; Lens, Crystalline; Middle Aged; Models, Chemical; Protein Folding; Stereoisomerism | 2001 |
[Clinical biochemical aspects of the prophylaxis and therapy of senile cataract with zinc aspartate (author's transl)].
Topics: Age Factors; Aged; Aspartic Acid; Cataract; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehydrogenase; Glycolysis; Hexokinase; Humans; L-Lactate Dehydrogenase; Lens, Crystalline; Long-Term Care; Malate Dehydrogenase; Zinc | 1978 |
Aspartic acid racemization in heavy molecular weight crystallins and water insoluble protein from normal human lenses and cataracts.
Topics: Adolescent; Adult; Aged; Aging; Aspartic Acid; Cataract; Child; Child, Preschool; Crystallins; Humans; Infant; Infant, Newborn; Lens, Crystalline; Middle Aged; Molecular Weight; Protein Conformation; Solubility; Stereoisomerism | 1978 |
Racemization in human lens: evidence of rapid insolubilization of specific polypeptides in cataract formation.
Topics: Age Factors; Aspartic Acid; Cataract; Crystallins; Humans; Isomerism; Lens, Crystalline; Peptides; Solubility | 1978 |
Aspartic acid racemisation in the human lens during ageing and in cataract formation.
Topics: Aging; Aspartic Acid; Cataract; Humans; Lens, Crystalline; Stereoisomerism | 1977 |
Contemporary possibilities of medicamentous prevention of cataract.
Topics: Adult; Aged; Aspartic Acid; Cataract; Drug Combinations; Female; Humans; Indazoles; Inosine Monophosphate; Male; Middle Aged; Niacinamide; Parabens; Thimerosal; Visual Acuity | 1990 |
The sequences of two peptides from cataract lenses suggest they arise by deamidation.
Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cataract; Cattle; Crystallins; Deamination; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptide Fragments; Peptides; Rabbits; Radioimmunoassay; Sequence Homology, Nucleic Acid; Trypsin | 1990 |
Total hydrolysis of proteins with strongly reduced racemization of amino acids.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Carboxypeptidases; Cataract; Female; Humans; Hydrolysis; Lens, Crystalline; Leucyl Aminopeptidase; Male; Middle Aged; Peptides; Pronase; Proteins; Spectrophotometry, Ultraviolet; Temperature | 1990 |
Racemization of aspartyl residues in proteins from normal and cataractous human lenses: an aging process without involvement in cataract formation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartic Acid; Cataract; Crystallins; Humans; Isomerism; Lens, Crystalline; Middle Aged | 1989 |
D-amino acid in irradiated and aged mouse.
Topics: Aging; Amino Acids; Animals; Aspartic Acid; Cataract; Crystallins; Male; Mice; Mice, Inbred Strains; Molecular Conformation; Skin; Whole-Body Irradiation | 1986 |
Lenticular and fundus changes induced by the intraocular infusion of sodium aspartate.
Topics: Animals; Aspartic Acid; Cataract; Fundus Oculi; Haplorhini; Injections; Intraocular Pressure; Lens, Crystalline; Macaca; Ophthalmoscopy; Retina; Retinal Vessels; Sodium; Vitreous Body | 1974 |
Some characteristics of the p-chlorophenylalanine-induced cataract.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Cataract; Chromatography, Gas; Crystallins; Electrophoresis; Female; Fenclonine; Glutathione; Glycine; Lens, Crystalline; Male; Ornithine; Rats; Serine; Threonine | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Protein metabolism in human senile cataract.
Topics: Adenosine Triphosphate; Aged; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Transport; Cataract; Crystallins; Guanosine Triphosphate; Humans; Lens, Crystalline; Leucine; Rabbits; Tritium | 1971 |