aspartic acid has been researched along with Carcinoma, Hepatocellular in 44 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Molybdenum dioxide-gadolinium-arginine/glycine/aspartic acid (MoS₂-Gd-RGD) sequences targeting nano-contrast agents that specifically bind to human hepatocellular carcinoma (HCC) HepG₂ cells were synthesized, and their targeting imaging effects on HCC cells and models were evaluated." | 4.02 | Molybdenum Dioxide (MoS₂)/Gadolinium (Gd) Containing Arginine-Glycine-Aspartic Acid (RGD) Sequences as New Nano-Contrast Agent for Cancer Magnetic Resonance Imaging (MRI). ( Hao, X; Li, W, 2021) |
| " In this work, novel rodlike supramolecular nanoassemblies (CNC @CB[8] @ PGEA) of degradable poly(aspartic acid) (PAsp) derivatives-grafted cellulose nanocrystals (CNCs) and hydroxyl-rich polycations (ethanolamine-functionalized poly(glycidyl methacrylate), PGEA) are proposed via typical cucurbit[8]uril (CB[8])-based host-guest interactions for delivery of different ncRNAs to treat hepatocellular carcinoma (HCC)." | 3.88 | Rodlike Supramolecular Nanoassemblies of Degradable Poly(Aspartic Acid) Derivatives and Hydroxyl-Rich Polycations for Effective Delivery of Versatile Tumor-Suppressive ncRNAs. ( Li, RQ; Liu, W; Pan, W; Song, HQ; Xu, FJ; Yang, M; Yu, B, 2018) |
| " Univariate analyses were conducted to determine the association among gender, age, hepatocellular carcinoma, hepatitis B e antigen-positive status, HBV-DNA level and tyrosine-methionine-aspartate-aspartate (YMDD) mutations on HBV recurrence in these patients." | 3.80 | Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients. ( Gao, YJ; Jin, B; Li, HW; Liu, ZW; Ma, XM; Meng, FP; Su, HB; Zhang, M; Zhao, JM, 2014) |
| "Hereditary hemochromatosis is the most frequent hereditary metabolic disorder, with lethal outcome without treatment." | 2.42 | [Iron storage disease]. ( Dávid, K; Horváth, G, 2004) |
| " No pathological toxic side effects were observed at two different doses, followed only by activation of the mononuclear phagocyte system (MPS) in the spleen, liver, lung, bone marrow, and lymph node." | 1.35 | Histological study on side effects and tumor targeting of a block copolymer micelle on rats. ( Honda, T; Kawaguchi, T; Nishihara, M; Yamamoto, T; Yokoyama, M, 2009) |
| "Alanosine treatment results in the inhibition of cell division, DNA synthesis, RNA and protein synthesis (in this order), and a depletion of the cells of adenosine triphosphate." | 1.26 | Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate. ( Graff, JC; Plagemann, PG, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (50.00) | 18.7374 |
| 1990's | 4 (9.09) | 18.2507 |
| 2000's | 3 (6.82) | 29.6817 |
| 2010's | 5 (11.36) | 24.3611 |
| 2020's | 10 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Sheng, Y | 1 |
| Chen, Y | 1 |
| Zeng, Z | 1 |
| Wu, W | 1 |
| Wang, J | 1 |
| Ma, Y | 1 |
| Lin, Y | 1 |
| Zhang, J | 1 |
| Huang, Y | 1 |
| Li, W | 2 |
| Zhu, Q | 1 |
| Wei, X | 1 |
| Li, S | 1 |
| Wisanwattana, W | 1 |
| Li, F | 1 |
| Liu, W | 3 |
| Suksamrarn, A | 1 |
| Zhang, G | 1 |
| Jiao, W | 1 |
| Wang, F | 1 |
| Chen, M | 1 |
| Zhang, C | 1 |
| Du, X | 1 |
| Liu, X | 1 |
| Xing, B | 1 |
| Pinto, L | 1 |
| Balbi, E | 1 |
| Halpern, M | 1 |
| Carius, L | 1 |
| Roma, J | 1 |
| Cardoso, SW | 1 |
| Grinsztejn, B | 1 |
| Veloso, VG | 1 |
| Pacheco, L | 1 |
| Perazzo, H | 1 |
| De Falco, P | 1 |
| Lazzarino, G | 1 |
| Felice, F | 1 |
| Desideri, E | 1 |
| Castelli, S | 1 |
| Salvatori, I | 1 |
| Ciccarone, F | 1 |
| Ciriolo, MR | 1 |
| Wang, H | 1 |
| Liu, Y | 1 |
| Cui, J | 1 |
| Tong, M | 1 |
| Guan, W | 1 |
| Cao, Z | 1 |
| Gao, X | 1 |
| Han, X | 1 |
| Xian, X | 1 |
| Li, J | 1 |
| Zhao, L | 1 |
| Cheng, YT | 1 |
| Zhu, T | 1 |
| Ma, YZ | 1 |
| Ding, YZ | 1 |
| Meng, LQ | 1 |
| Xue, L | 1 |
| Ji, LX | 1 |
| Bittaye, SO | 1 |
| Kambi, A | 1 |
| Tekanyi, MAI | 1 |
| Tamba, S | 1 |
| Sanneh, L | 1 |
| Sisawo, MM | 1 |
| Jatta, A | 1 |
| Fatty, G | 1 |
| Jeng, A | 1 |
| Jallow, MS | 1 |
| Leigh, O | 1 |
| Njie, R | 1 |
| Wai-Sun Wong, V | 1 |
| Kao, JH | 1 |
| Li, ZC | 1 |
| Li, Z | 1 |
| Li, C | 1 |
| Fang, JC | 1 |
| Li, XZ | 1 |
| Zhao, YN | 1 |
| Liang, CY | 1 |
| Hao, X | 1 |
| Ma, H | 1 |
| Jiang, C | 1 |
| Song, HQ | 1 |
| Pan, W | 1 |
| Li, RQ | 1 |
| Yu, B | 1 |
| Yang, M | 1 |
| Xu, FJ | 1 |
| Infantino, V | 1 |
| Dituri, F | 1 |
| Convertini, P | 1 |
| Santarsiero, A | 1 |
| Palmieri, F | 1 |
| Todisco, S | 1 |
| Mancarella, S | 1 |
| Giannelli, G | 1 |
| Iacobazzi, V | 1 |
| Gao, YJ | 1 |
| Zhang, M | 1 |
| Jin, B | 1 |
| Meng, FP | 1 |
| Ma, XM | 1 |
| Liu, ZW | 1 |
| Su, HB | 1 |
| Zhao, JM | 1 |
| Li, HW | 1 |
| Darpolor, MM | 1 |
| Basu, SS | 1 |
| Worth, A | 1 |
| Nelson, DS | 1 |
| Clarke-Katzenberg, RH | 1 |
| Glickson, JD | 1 |
| Kaplan, DE | 1 |
| Blair, IA | 1 |
| Kawaguchi, T | 1 |
| Honda, T | 1 |
| Nishihara, M | 1 |
| Yamamoto, T | 1 |
| Yokoyama, M | 1 |
| WAGLE, SR | 1 |
| MORRIS, HP | 3 |
| WEBER, G | 3 |
| Horváth, G | 1 |
| Dávid, K | 1 |
| Kitteringham, NR | 1 |
| Palmer, L | 1 |
| Owen, A | 1 |
| Lian, LY | 1 |
| Jenkins, R | 1 |
| Dowdall, S | 1 |
| Gilmore, I | 1 |
| Park, BK | 1 |
| Goldring, CE | 1 |
| Yuan, TT | 1 |
| Faruqi, A | 1 |
| Shih, JW | 1 |
| Shih, C | 1 |
| Sviridov, D | 1 |
| Pyle, L | 1 |
| Fidge, N | 1 |
| Conner, EA | 1 |
| Wirth, PJ | 1 |
| Mokotoff, M | 1 |
| Bagaglio, JF | 1 |
| Parikh, BS | 1 |
| Jackson, RC | 2 |
| Nakada, H | 1 |
| Funakoshi, I | 1 |
| Yamashina, I | 1 |
| Greenhouse, WV | 1 |
| Lehninger, AL | 1 |
| Graff, JC | 1 |
| Plagemann, PG | 2 |
| Clark, AW | 1 |
| Rudolph, FB | 1 |
| Keppler, DD | 1 |
| Okada, N | 1 |
| Shindo-Okada, N | 1 |
| Nishimura, S | 1 |
| Matsuno, T | 1 |
| Harley, EH | 1 |
| Sacks, S | 1 |
| Berman, P | 1 |
| Cohen, L | 2 |
| Simmonds, HA | 1 |
| Fairbanks, LD | 1 |
| Black, D | 1 |
| Hoffer, PB | 1 |
| Gottschalk, A | 1 |
| Cooney, DA | 1 |
| Yavelow, J | 1 |
| Zlotoff, R | 1 |
| Bergenstal, R | 1 |
| Burg, A | 1 |
| Morrison, R | 1 |
| Fleischman, R | 1 |
| Eagle, H | 1 |
| Washington, CL | 1 |
| Levy, M | 1 |
| Mayfield, ED | 1 |
| Lyman, K | 1 |
| Bresnick, E | 1 |
| Patterson, MK | 1 |
| Orr, GR | 1 |
| Bhide, SV | 1 |
| Maley, F | 1 |
| Maley, GF | 1 |
| Chou, TC | 1 |
| Handschumacher, RE | 1 |
| Briscoe, WT | 1 |
| Taylor, W | 1 |
| Griffin, AC | 1 |
| Duff, R | 1 |
| Rapp, F | 1 |
| Tatibana, M | 1 |
| Shigesada, K | 1 |
3 reviews available for aspartic acid and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; D | 2004 |
Tumor scanning agents.
Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Anti | 1974 |
Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Carcinoma, He | 1972 |
41 other studies available for aspartic acid and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming.
Topics: Antineoplastic Agents; Bibenzyls; Carcinoma, Hepatocellular; Cell Proliferation; Click Chemistry; Ge | 2022 |
Long noncoding RNA LINC01234 promotes hepatocellular carcinoma progression through orchestrating aspartate metabolic reprogramming.
Topics: Animals; Argininosuccinate Synthase; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cel | 2022 |
Effectiveness of Direct-acting Agents After Liver Transplantation A Real-life Study in Rio de Janeiro.
Topics: Antiviral Agents; Aspartic Acid; Biomarkers; Brazil; Carcinoma, Hepatocellular; Female; Hepacivirus; | 2022 |
Hindering NAT8L expression in hepatocellular carcinoma increases cytosolic aspartate delivery that fosters pentose phosphate pathway and purine biosynthesis promoting cell proliferation.
Topics: Acetyltransferases; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Humans; L | 2023 |
Effects of Scutellaria strigillosa Hemsl. extract on HepG2 cell proliferation and apoptosis through binding to aspartate β-hydroxylase.
Topics: Apoptosis; Aspartic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Hep G2 Cells; Humans; Liver | 2023 |
[Moxibustion with seed-size moxa cone enhances anti-tumor effect of cyclophosphamide on Hepa1-6 hepatoma-bearing mice by regulating apoptosis factor cysteine family].
Topics: Animals; Apoptosis; Aspartic Acid; Body Weight; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cyc | 2023 |
Clinical manifestation, staging and prognosis of hepatocellular carcinoma in Gambian patients.
Topics: Abdominal Pain; Adult; Aspartic Acid; Carcinoma, Hepatocellular; Female; Gambia; Hepatitis B Surface | 2023 |
Letter: elevated aspartate aminotransferase and aspartate aminotransferase to alanine aminotransferase ratio predicts poor survival in hepatocellular carcinoma after resection-Authors' reply.
Topics: Alanine Transaminase; Asia, Eastern; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Hepatoce | 2020 |
Letter: elevated aspartate aminotransferase and aspartate aminotransferase to alanine aminotransferase ratio predicts poor survival in hepatocellular carcinoma after resection.
Topics: Alanine Transaminase; Asia, Eastern; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Hepatoce | 2020 |
Molybdenum Dioxide (MoS₂)/Gadolinium (Gd) Containing Arginine-Glycine-Aspartic Acid (RGD) Sequences as New Nano-Contrast Agent for Cancer Magnetic Resonance Imaging (MRI).
Topics: Animals; Arginine; Aspartic Acid; Carcinoma, Hepatocellular; Contrast Media; Gadolinium; Glycine; Li | 2021 |
Dehydroascorbic Acid and pGPMA Dual Modified pH-Sensitive Polymeric Micelles for Target Treatment of Liver Cancer.
Topics: Acrylamides; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Dehydroascorbic Ac | 2018 |
Rodlike Supramolecular Nanoassemblies of Degradable Poly(Aspartic Acid) Derivatives and Hydroxyl-Rich Polycations for Effective Delivery of Versatile Tumor-Suppressive ncRNAs.
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Gene Transfer Techniques; Genetic Vectors; Humans; Liver N | 2018 |
Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma.
Topics: Amino Acid Transport Systems, Acidic; Antiporters; Aspartic Acid; Brain; Carcinoma, Hepatocellular; | 2019 |
Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients.
Topics: Adult; Age Factors; Antiviral Agents; Aspartic Acid; Carcinoma, Hepatocellular; China; DNA, Viral; D | 2014 |
The aspartate metabolism pathway is differentiable in human hepatocellular carcinoma: transcriptomics and (13) C-isotope based metabolomics.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Aspartic Acid; Carbon Isotopes; Carcinoma, Hepatocellular; | 2014 |
Histological study on side effects and tumor targeting of a block copolymer micelle on rats.
Topics: Animals; Ascites; Aspartic Acid; Biopolymers; Biotinylation; Body Weight; Carcinoma, Hepatocellular; | 2009 |
COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES.
Topics: Alanine; Amino Acids; Aspartic Acid; Carcinoma, Hepatocellular; Glycine; Histocytochemistry; Isoleuc | 1963 |
Detection and biochemical characterisation of a novel polymorphism in the human GSTP1 gene.
Topics: Alleles; Amino Acid Substitution; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Circul | 2007 |
The mechanism of natural occurrence of two closely linked HBV precore predominant mutations.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Calorimetry; Carcinoma, Hepatocellular; Cell Line | 1995 |
Identification of a sequence of apolipoprotein A-I associated with the efflux of intracellular cholesterol to human serum and apolipoprotein A-I containing particles.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Apolipoprotein A-I; Arginine; Aspartic Acid; Binding Si | 1996 |
Protein alterations associated with gene amplification in cultured human and rodent cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; CH | 1996 |
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Hydr | 1975 |
Neoplastic transformation-linked alterations in adenylosuccinate synthetase activity.
Topics: Aging; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Inosine N | 1975 |
The isolation and characterization of glycopeptides and mucopolysaccharides from plasma membranes of an ascites hepatoma, AH 130.
Topics: Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Membrane; Female; Glycopeptides; Glycosamino | 1975 |
Occurrence of the malate-aspartate shuttle in various tumor types.
Topics: Aminooxyacetic Acid; Animals; Antimycin A; Aspartic Acid; Carcinoma, Ehrlich Tumor; Carcinoma, Hepat | 1976 |
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatoc | 1976 |
Regulation of purine metabolism. Adenylosuccinate synthetase from Novikoff ascites tumor cells.
Topics: Adenosine Monophosphate; Animals; Anti-Bacterial Agents; Aspartic Acid; Carcinoma, Hepatocellular; F | 1976 |
Aspartate carbamoyltransferase inhibition and uridylate trapping result in a synergistic depression of uridine triphosphate in hepatoma cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma, Hepatocellular; Cells, Cultured; | 1977 |
Isolation of mammalian tRNAAsp and tRNATyr by lectin-Sepharose affinity column chromatography.
Topics: Animals; Aspartic Acid; Carcinoma, Hepatocellular; Chromatography, Affinity; Concanavalin A; Liver; | 1977 |
Enzymes of the purine ribonucleotide cycle in rat hepatomas and kidney tumors.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Animals, Newborn; Antimetab | 1977 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in HuH13 human hepatoma cells.
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Cytosol; Humans; Kinetics; Liver Neoplasms; Malates; NAD; | 1992 |
Source and fate of circulating pyrimidines.
Topics: Aspartic Acid; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, High Pres | 1986 |
Azotomycin--toxicologic, biochemical and pharmacologic studies in mice.
Topics: Animals; Antibiotics, Antineoplastic; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Ataxia | 1974 |
The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize. II. Glutamic acid and glutamine; aspartic acid and asparagine.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Culture Techni | 1966 |
Incorporation of bicarbonate-14 C into pyrimidines and into ribonucleic acid of the Novikoff ascites tumor cell.
Topics: Ammonia; Animals; Aspartic Acid; Bicarbonates; Carcinoma, Hepatocellular; Chromatography, Ion Exchan | 1967 |
Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonium Chloride; Animals; Asparagine; Aspartic Acid; | 1968 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; | 1971 |
Comparative study of metabolic profiles of primary hepatoma, regenerating liver, and liver in newborn Swiss mice.
Topics: Acetates; Aldehyde-Lyases; Amides; Animals; Animals, Newborn; Aspartic Acid; Carbamates; Carcinoma, | 1971 |
The apparent induction of thymidylate synthetase by amethopterin.
Topics: Animals; Aspartic Acid; Benzoates; Carcinoma, Hepatocellular; Enzyme Induction; Folic Acid; Hepatect | 1971 |
Production of L-asparagine by tumor cells and the effect of asparagine analogs.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Azo Compounds; Bromine; Carbon Isotop | 1972 |
Aspartyl transfer RNA profiles in normal and cancer cells.
Topics: Animals; Ascites; Aspartic Acid; Breast Neoplasms; Carbon Isotopes; Carcinoma, Hepatocellular; Cell | 1972 |