Page last updated: 2024-08-17

aspartic acid and Cancer of Lung

aspartic acid has been researched along with Cancer of Lung in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (32.61)	18.7374
1990's	5 (10.87)	18.2507
2000's	9 (19.57)	29.6817
2010's	14 (30.43)	24.3611
2020's	3 (6.52)	2.80

Authors

Authors	Studies
DI, LQ; Huang, X; Lu, YY; Luo, ZC; Qi, MY; Shan, JJ; Zhang, W	1
Hanada, K; Itatani, Y; Kawada, K; Maekawa, H; Miyoshi, H; Nishikawa, G; Obama, K; Taketo, MM	1
Choudhuri, R; Cook, JA; Gamson, J; Gohain, S; Leiker, AJ; Mathias, A; Mitchell, JB; Naz, S; Preston, O; Sowers, AL; Van Waes, C	1
Bellvert, F; Bertero, T; Boulter, E; Bourget, I; Bozec, A; Bulavin, DV; Chan, SY; Estrach, S; Feral, CC; Gaggioli, C; Grasset, EM; Hofman, P; Meneguzzi, G; Oldham, WM; Pisano, S	1
Bouras, N; Bousahba, A; de Fraipont, F; Kebir, FZE; Megaïz, A; Sahraoui, T	1
Huo, DF; Lu, LN; Qiu, MF; Wu, HB; Xin, X; Zhou, Y	1
Chen, M; Guo, J; Liang, G; Shi, L; Tan, X; Wang, Y; Xian, L	1
Furukawa, M; Hashida, S; Higasa, K; Ichimura, K; Kiura, K; Matsuda, F; Matsuo, K; Miyoshi, S; Sakaguchi, M; Shien, K; Soh, J; Takigawa, N; Toyooka, S; Tsukuda, K; Yamamoto, H	1
Gandhi, V; Panandikar, A; Sen, S; Wang, J; Yin, H	1
Du, D; Lin, Y; Luo, Y; Wang, X	1
Ahn, JM; Chen, PH; DeBerardinis, RJ; Dospoy, P; Frink, RE; Huffman, KE; Kim, DH; Kim, HS; Kim, J; Larsen, JE; Lewis, C; Lou, TF; Ma, X; Minna, JD; Sethuraman, D; Srivastva, P; Um, SW; White, MA; Yoo, H	1
Hong, KM; Jang, H; Kang, JH; Kim, SY; Lee, C; Lee, JS; Lee, SH; Nam, B; Seong, TW; Son, J	1
Botuyan, MV; Bruns, CJ; Cui, G; Klein, BJ; Kutateladze, TG; Lin, K; Lu, Y; Mer, G; Shi, X; Wang, X; Yuan, C; Zhao, Y	1
Hong, D; Hong, KM; Kang, JH; Kim, SY; Lee, JS; Lee, SH; Son, J; Song, J	1
Che, X; He, Z; Kou, L; Li, J; Lian, H; Luo, Q; Sun, J; Tao, W; Yang, B	1
Alzani, R; Ciomei, M; Degrassi, A; Fanti, S; Giusti, AM; Nanni, C; Patton, V; Pesenti, E; Russo, M; Texido, G	1
Abdelmelek, MF; Blumenschein, GR; Byers, LA; Chen, L; Coombes, KR; Diao, L; Herbst, RS; Heymach, JV; Hong, WK; Ihle, NT; Kim, ES; Larsen, JE; Lee, JJ; Lippman, SM; Liu, S; Minna, JD; Papadimitrakopoulou, V; Powis, G; Saintigny, P; Tang, X; Tsao, A; Wang, J; Wistuba, II; Zhang, S	1
Fu, J; Li, F; Li, S; Peng, S; Wu, D; Yu, G	1
Liang, G; Lin, DX; Lu, WF; Miao, XP; Qi, J; Tan, W; Wu, M; Xing, DY; Yu, CY; Zhou, CN	1
FUJII, K; IMADA, R; MATSUURA, K	1
LORINCZ, AB; RYAN, WL	1
FAGE, P	1
Ciszkowska-Łysoń, B; Janowicz-Zebrowska, A; Królicki, L; Krzakowski, M; Tacikowska, M; Teska, A	1
Hamajima, N; Ito, H; Kang, D; Lee, KM; Matsuo, K; Mitsudomi, T; Saito, T; Sato, S; Sugiura, T; Tajima, K; Ueda, R; Yasue, T; Yoo, KY	1
Esplin, ED; Evans, GA; Martinez, B; Mumby, MC; Ramos, P; Tomlinson, GE	1
Creech, RH; Ettinger, DS; Ferraro, JA; Ruckdeschel, JC; Tritchler, D; Vogl, SE; Woll, J	1
Anderson, LW; Cysyk, RL; Monks, A; Strong, J	1
Creech, RH; Earhart, R; Ettinger, DS; Tritchler, D	1
Hageman, JJ; Koomen, GJ; Pandit, UK; Wanner, MJ	1
Ardalan, B; Cooney, DA; Cysyk, RL; Han, N; Hankerson, JG; Harley, C; Jayaram, HN; Johnson, RK; Kensler, TW; Mutter, G; Reck, LJ	1
Cooney, DA; Kensler, TW; Reck, LJ	1
Cleaveland, ES; Cooney, DA; Ford, H; Kelley, JA; Paull, K; Zaharevitz, DW	1
Paranavitana, CM	1
Arioka, H; Fukumoto, H; Fukuoka, K; Ishida, T; Iwamoto, Y; Kurokawa, H; Narita, N; Nishio, K; Saijo, N; Suzuki, T; Tomonari, A; Usuda, J	1
Hei, TK; Piao, CQ	1
Pham, HT; Ruediger, R; Walter, G	1
Hamaguchi, T; Hrushesky, WJ; Kakizoe, T; Kataoka, K; Kawaguchi, T; Matsumura, Y; Mizumura, Y; Moriyasu, F; Nishiyama, N	1
Hall, EJ; Hei, TK; Piao, CQ; Willey, JC; Wu, LJ	1
Handschumacher, RE; Moyer, JD	1
Johnson, RK; Stark, GR; Swyryd, EA	1
Johnson, RK	1
Goldin, A; Inouye, T; Johnson, RK; Stark, GR	1
Giga-Hama, Y; Goto, H; Isoai, A; Kumagai, H; Ueno, Y	1
Ardalan, B; Benedetto, P; Feun, L; Fodor, M; Livingstone, A; Morrell, L; Richman, S; Savaraj, N; Sridhar, KS; Waldman, S	1
Boschetti, E; Daussin, F; Delmotte, F; Monsigny, M	1
Chang, M; Creagan, ET; Cullinan, SA; Ebbert, L; Mailliard, JA; Morton, RF; Veeder, MH	1

Reviews

1 review(s) available for aspartic acid and Cancer of Lung

Article	Year
Polymorphism of ERCC2 Asp312Asn with lung cancer risk: evidence from 20,101 subjects. Genetic testing and molecular biomarkers, 2014, Volume: 18, Issue:1 Topics: Asparagine; Aspartic Acid; Case-Control Studies; Humans; Lung Neoplasms; Polymorphism, Genetic; Xeroderma Pigmentosum Group D Protein	2014

Trials

4 trial(s) available for aspartic acid and Cancer of Lung

Article	Year
Phase II study of PALA, amsacrine, teniposide, and zinostatin in small cell lung carcinoma (EST 2579). Cancer treatment reports, 1984, Volume: 68, Issue:9 Topics: Aminoacridines; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Aspartic Acid; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Drug Evaluation; Humans; Lung Neoplasms; Phosphonoacetic Acid; Random Allocation; Teniposide; Zinostatin	1984
Phase II study of PALA and PCNU in the treatment of non-small cell lung cancer (EST 2580): an Eastern Cooperative Oncology Group study. Cancer treatment reports, 1984, Volume: 68, Issue:10 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nitrosourea Compounds; Organophosphorus Compounds; Phosphonoacetic Acid; Random Allocation	1984
A phase I, II study of high-dose 5-fluorouracil and high-dose leucovorin with low-dose phosphonacetyl-L-aspartic acid in patients with advanced malignancies. Cancer, 1991, Sep-15, Volume: 68, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Breast Neoplasms; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Humans; Leucovorin; Lung Neoplasms; Male; Middle Aged; Neoplasms; Phosphonoacetic Acid; Prognosis	1991
Phase II studies of single-agent cimetidine and the combination N-phosphonacetyl-L-aspartate (NSC-224131) plus L-alanosine (NSC-153353) in advanced malignant melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:7 Topics: Alanine; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cimetidine; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Melanoma; Middle Aged; Phosphonoacetic Acid; Pleural Neoplasms; Soft Tissue Neoplasms	1987

Other Studies

41 other study(ies) available for aspartic acid and Cancer of Lung

Article	Year
[Mechanism of Cordyceps militaris against non-small cell lung cancer: based on serum metabolomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:18 Topics: Alanine; Animals; Arginine; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cordyceps; Glutamic Acid; Glutamine; Glyoxylates; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Nitrogen; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine	2022
Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells. Cells, 2022, 10-18, Volume: 11, Issue:20 Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Spheroids, Cellular; Xenograft Model Antitumor Assays	2022
Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis. International journal of radiation oncology, biology, physics, 2021, 08-01, Volume: 110, Issue:5 Topics: Animals; Aspartic Acid; Benzamides; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA Repair; Down-Regulation; G2 Phase Cell Cycle Checkpoints; Head and Neck Neoplasms; HSP90 Heat-Shock Proteins; Humans; Isoindoles; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Metabolomics; Mice; Mice, Nude; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Nucleotides; Radiation Tolerance; Squamous Cell Carcinoma of Head and Neck; Xenograft Model Antitumor Assays	2021
Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy. Cell metabolism, 2019, 01-08, Volume: 29, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Breast Neoplasms; Cancer-Associated Fibroblasts; Carcinoma; Cell Line; Extracellular Matrix; Female; Glutamic Acid; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins	2019
[In silico study of a functional mutation associated with non-small cell lung cancer: G12D mutation of exon 2 in KRAS gene]. Annales de biologie clinique, 2019, 06-01, Volume: 77, Issue:3 Topics: Algeria; Amino Acid Substitution; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Computational Biology; Databases, Genetic; DNA Mutational Analysis; Exons; Genetic Association Studies; Glycine; Humans; Lung Neoplasms; Models, Molecular; Mutation, Missense; Proto-Oncogene Mas; Proto-Oncogene Proteins p21(ras); Software	2019
[Preparation, characterization and Calu-3 cellular uptake of three kinds of poly(b-benzyl-L-amino)block-poly(ethylene glycol) nanoparticles]. Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:4 Topics: Adenocarcinoma; Administration, Intranasal; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Cell Line, Tumor; Cell Survival; Curcumin; Drug Carriers; Ethylene Glycol; Humans; Lung Neoplasms; Lysine; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglutamic Acid	2013
Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas. Journal of the National Cancer Institute, 2014, Volume: 106, Issue:1 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Asian People; Aspartic Acid; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Glutamic Acid; Glycine; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Pedigree; Receptor, ErbB-2; Valine	2014
Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug. International journal of oncology, 2015, Volume: 47, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Aspartic Acid; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin A; Cyclin-Dependent Kinase 2; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Mice; Mice, Nude; Phosphonoacetic Acid; Up-Regulation	2015
Hyaluronic acid-conjugated apoferritin nanocages for lung cancer targeted drug delivery. Biomaterials science, 2015, Oct-15, Volume: 3, Issue:10 Topics: Antineoplastic Agents; Apoferritins; Aspartic Acid; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hydrogen-Ion Concentration; Lung Neoplasms	2015
Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker. Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:1 Topics: Acetyltransferases; Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Blood-Brain Barrier; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Lung Neoplasms; Male; Middle Aged; RNA, Small Interfering; Sequence Analysis, RNA	2016
Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion. Oncotarget, 2016, Aug-02, Volume: 7, Issue:31 Topics: Action Potentials; Adenosine Triphosphate; Aldehyde Dehydrogenase; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cytosol; Female; Gossypol; Humans; Lung Neoplasms; Malates; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; NAD; NADP; Neoplasm Transplantation; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Phenformin; RNA, Small Interfering	2016
PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation. Cell reports, 2016, 10-18, Volume: 17, Issue:4 Topics: Acetylation; Amino Acid Sequence; Antigens, Neoplasm; Aspartic Acid; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Glutamic Acid; Histones; Humans; Lung Neoplasms; Lysine; Methylation; Models, Biological; Models, Molecular; Mutation; Protein Binding; Protein Domains; Transcription Factors; Tumor Suppressor Protein p53	2016
Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC. Cell death & disease, 2016, 12-08, Volume: 7, Issue:12 Topics: A549 Cells; Adenosine Triphosphate; Animals; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Death; Cell Proliferation; Cell Survival; Cytosol; Drug Synergism; Fluorouracil; Gene Knockdown Techniques; Glutamic Acid; Glutaminase; Glutamine; Lung Neoplasms; Malates; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; NAD; Oxidation-Reduction; Sulfides; Thiadiazoles; Thymidylate Synthase; Xenograft Model Antitumor Assays	2016
ATB Biomaterials science, 2017, Jan-31, Volume: 5, Issue:2 Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Antineoplastic Agents; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Liposomes; Lung Neoplasms; Microscopy, Confocal; Molecular Structure; Taxoids	2017
Efficacy of PHA-848125, a cyclin-dependent kinase inhibitor, on the K-Ras(G12D)LA2 lung adenocarcinoma transgenic mouse model: evaluation by multimodality imaging. Molecular cancer therapeutics, 2010, Volume: 9, Issue:3 Topics: Adenocarcinoma; Amino Acid Substitution; Animals; Antineoplastic Agents; Aspartic Acid; Cyclin-Dependent Kinases; Diagnostic Imaging; Disease Models, Animal; Drug Evaluation, Preclinical; Genes, ras; Glycine; Humans; Lung Neoplasms; Mice; Mice, Transgenic; Mutant Proteins; Pyrazoles; Quinazolines; Treatment Outcome	2010
Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. Journal of the National Cancer Institute, 2012, Feb-08, Volume: 104, Issue:3 Topics: Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Clinical Trials, Phase II as Topic; Cysteine; Disease-Free Survival; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Vectors; Glycine; Humans; Immunoblotting; Immunoprecipitation; Kaplan-Meier Estimate; Lentivirus; Lung Neoplasms; Microarray Analysis; Molecular Targeted Therapy; Mutation; Proto-Oncogene Proteins c-akt; Randomized Controlled Trials as Topic; Signal Transduction; TOR Serine-Threonine Kinases; Treatment Outcome; Valine	2012
[An antimetastatic study of Arg-Asp (RD) on salivary adenoid cystic carcinoma in vivo]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2002, Volume: 37, Issue:2 Topics: Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Carcinoma, Adenoid Cystic; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Salivary Gland Neoplasms	2002
[Association of genetic polymorphisms in the DNA repair gene XPD with risk of lung and esophageal cancer in a Chinese population in Beijing]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2003, Volume: 20, Issue:1 Topics: Adenocarcinoma; Asparagine; Aspartic Acid; Carcinoma, Squamous Cell; China; DNA; DNA Helicases; DNA Repair; DNA-Binding Proteins; Esophageal Neoplasms; Female; Gene Frequency; Genotype; Humans; Logistic Models; Lung Neoplasms; Male; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proteins; Risk Factors; Smoking; Transcription Factors; Xeroderma Pigmentosum Group D Protein	2003
[L-ASPARTIC ACID K,MG SALTS FOR RADIATION SICKNESS]. Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1963, Volume: 23 Topics: Animals; Aspartic Acid; Female; Japan; Lung Neoplasms; Magnesium; Mice; Neoplasms; Potassium; Radiation Injuries; Research; Salts; Statistics as Topic; Uterine Neoplasms	1963
FREE AMINO ACIDS OF HUMAN BREAST CANCER. The Nebraska state medical journal, 1964, Volume: 49 Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine	1964
[CLINICAL TRIALS OF A DRUG COMBINATION GROUPING THE ANTITOXIC FRACTIONS OF THE LIVER WITH ASPARTATES AND EXTRACTS OF THE LIVER WITH YEASTS]. Toulouse medical, 1964, Volume: 65 Topics: Arteritis; Aspartic Acid; Drug Combinations; Geriatrics; Hernia, Diaphragmatic; Hernia, Hiatal; Humans; Liver Cirrhosis; Liver Extracts; Lung Neoplasms; Magnesium; Male; Polyradiculopathy; Potassium; Prostatic Neoplasms; Sinusitis; Tuberculosis; Tuberculosis, Pulmonary; Yeasts	1964
[Brain metabolic disorders after chemotherapy in the study by magnetic resonance spectroscopy]. Neurologia i neurochirurgia polska, 2003, Volume: 37, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Female; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Male; Middle Aged	2003
Gene-environment interactions between the smoking habit and polymorphisms in the DNA repair genes, APE1 Asp148Glu and XRCC1 Arg399Gln, in Japanese lung cancer risk. Carcinogenesis, 2004, Volume: 25, Issue:8 Topics: Adult; Aged; Alleles; Arginine; Aspartic Acid; Codon; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Binding Proteins; Environment; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutamine; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk; Risk Factors; Smoking; X-ray Repair Cross Complementing Protein 1	2004
The glycine 90 to aspartate alteration in the Abeta subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function. Genes, chromosomes & cancer, 2006, Volume: 45, Issue:2 Topics: Amino Acid Substitution; Aspartic Acid; Base Sequence; Breast Neoplasms; DNA Primers; Female; Genetic Vectors; Glycine; Humans; Immunoprecipitation; Lung Neoplasms; Male; Oligonucleotide Array Sequence Analysis; Pedigree; Phosphoprotein Phosphatases; Polymerase Chain Reaction; Polymorphism, Genetic; Protein Phosphatase 2	2006
Flux through the de novo pyrimidine pathway in vivo. Effect of N-phosphonacetyl-L-aspartate, a potent inhibitor of aspartate transcarbamylase. The Journal of biological chemistry, 1983, Nov-25, Volume: 258, Issue:22 Topics: Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Dioxide; Kinetics; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Oxygen; Phosphonoacetic Acid; Pyrimidines	1983
Potential carcinostatics. 4. Synthesis and biological properties of erythro- and threo-beta-fluoroaspartic acid and erythro-beta-fluoroasparagine. Journal of medicinal chemistry, 1980, Volume: 23, Issue:1 Topics: Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Female; Leukemia L5178; Lung Neoplasms; Male; Mice; Models, Molecular; Molecular Conformation; Neoplasms, Experimental	1980
Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid. Cancer research, 1981, Volume: 41, Issue:3 Topics: Amides; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Lung Neoplasms; Mice; Neoplasms, Experimental; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose	1981
Therapeutic effects of acivicin and N-(phosphonacetyl)-L-aspartic acid in a biochemically designed trial against a N-(phosphonacetyl)-L-aspartic acid-resistant variant of the Lewis lung carcinoma. Cancer research, 1981, Volume: 41, Issue:3 Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma; Drug Therapy, Combination; Glycine; Isoxazoles; Ligases; Lung Neoplasms; Neoplasms, Experimental; Organophosphorus Compounds; Oxazoles; Phosphonoacetic Acid; Pyrimidines; Rats	1981
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar. Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3 Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colonic Neoplasms; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Female; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lung Neoplasms; Male; Melanoma; Mitochondria; Orotic Acid; Ovarian Neoplasms; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Prostatic Neoplasms; Ribonucleotides; Sodium Bicarbonate; Software; Tumor Cells, Cultured	1996
Non-radioactive detection of K-ras mutations by nested allele specific PCR and oligonucleotide hybridization. Molecular and cellular probes, 1998, Volume: 12, Issue:5 Topics: Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Breast Neoplasms; Codon; Colonic Neoplasms; DNA Mutational Analysis; DNA Primers; Female; Genes, ras; Glycine; Heterozygote; Humans; Lung Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Probes; Point Mutation; Polymerase Chain Reaction; Transplantation, Heterologous; Tumor Cells, Cultured	1998
Ectopic p16(ink4) expression enhances CPT-11-induced apoptosis through increased delay in S-phase progression in human non-small-cell-lung-cancer cells. International journal of cancer, 2000, Apr-15, Volume: 86, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Aspartic Acid; Camptothecin; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspase Inhibitors; Caspases; Cyclin A; Cyclin-Dependent Kinase Inhibitor p16; DNA Fragmentation; DNA, Complementary; Enzyme Activation; Gene Expression; Humans; Irinotecan; Lung Neoplasms; Protease Inhibitors; S Phase; Time Factors; Transfection; Tumor Cells, Cultured	2000
Gene amplification and microsatellite instability induced in tumorigenic human bronchial epithelial cells by alpha particles and heavy ions. Radiation research, 2001, Volume: 155, Issue:1 Pt 2 Topics: Alpha Particles; Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Bronchi; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Transformation, Neoplastic; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 3; Dihydroorotase; Drug Resistance, Neoplasm; Epithelial Cells; Gene Amplification; Heavy Ions; Humans; Iron; Lung Neoplasms; Mice; Mice, Nude; Microsatellite Repeats; Multienzyme Complexes; Neoplasm Proteins; Neoplasms, Radiation-Induced; Phosphonoacetic Acid; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2001
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene. Oncogene, 2001, Jan-04, Volume: 20, Issue:1 Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan	2001
Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity. Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:3 Topics: Animals; Aspartic Acid; Breast Neoplasms; Cell Survival; Cisplatin; Colonic Neoplasms; Drug Carriers; Female; Humans; Kidney; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Micelles; Polyethylene Glycols; Stomach Neoplasms; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured	2001
Genomic instability and tumorigenic induction in immortalized human bronchial epithelial cells by heavy ions. Advances in space research : the official journal of the Committee on Space Research (COSPAR), 1998, Volume: 22, Issue:12 Topics: Alpha Particles; Animals; Antineoplastic Agents; Aspartic Acid; Bronchi; Cell Fusion; Cell Line, Transformed; Cell Transformation, Neoplastic; Epithelial Cells; Gene Amplification; Genes, Tumor Suppressor; Heavy Ions; Humans; Iron; Linear Energy Transfer; Lung Neoplasms; Mercaptoethylamines; Mice; Mice, Nude; Phosphonoacetic Acid; Radiation-Protective Agents; Tumor Cells, Cultured	1998
Selective inhibition of pyrimidine synthesis and depletion of nucleotide pools by N-(phosphonacetyl)-L-aspartate. Cancer research, 1979, Volume: 39, Issue:8 Topics: Animals; Aspartic Acid; Cells, Cultured; Female; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleotides; Pyrimidines; Ribonucleosides; Uridine	1979
Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase. Cancer research, 1978, Volume: 38, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Cells, Cultured; Cyclophosphamide; Drug Evaluation, Preclinical; Glioma; Graft Rejection; Leukemia, Experimental; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid	1978
Reversal of toxicity and antitumor activity of N-(phosphonacetyl)-L-aspartate by uridine or carbamyl-DL-asparate in vivo. Biochemical pharmacology, 1977, Jan-01, Volume: 26, Issue:1 Topics: Animals; Antineoplastic Agents; Aspartic Acid; Body Weight; Carbamates; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine	1977
Antitumor activity of N-(phosphonacetyl)-L-aspartic acid, a transition-state inhibitor of aspartate transcarbamylase. Cancer research, 1976, Volume: 36, Issue:8 Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Drug Administration Schedule; Female; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Neoplasms, Experimental; Organophosphorus Compounds; Osteosarcoma; Phosphonoacetic Acid	1976
A novel Arg-Gly-Asp containing peptide specific for platelet aggregation and its effect on tumor metastasis: a possible mechanism of RGD peptide-mediated inhibition of tumor metastasis. Cancer letters, 1992, Aug-31, Volume: 65, Issue:3 Topics: Animals; Anticarcinogenic Agents; Arginine; Aspartic Acid; Carcinoma, Squamous Cell; Cell Adhesion; Collagen; Female; Fibronectins; Glycine; Glycoproteins; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Oligopeptides; Peptides, Cyclic; Platelet Aggregation; Protein Binding; Vitronectin	1992
p-Benzylthiocarbamoyl-aspartyl-daunorubicin-substituted polytrisacryl. A new drug acid-labile arm-carrier conjugate. European journal of biochemistry, 1988, Oct-01, Volume: 176, Issue:3 Topics: Acrylates; Aspartic Acid; Binding Sites; Carcinoma; Cell Survival; Daunorubicin; Hydrogen-Ion Concentration; Lung Neoplasms; Pharmaceutical Vehicles; Thiocarbamates; Tumor Cells, Cultured	1988