aspartic acid has been researched along with Cancer of Liver in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (45.76) | 18.7374 |
| 1990's | 11 (18.64) | 18.2507 |
| 2000's | 4 (6.78) | 29.6817 |
| 2010's | 6 (10.17) | 24.3611 |
| 2020's | 11 (18.64) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Huang, Y; Jiao, W; Li, F; Li, S; Li, W; Lin, Y; Liu, W; Ma, Y; Sheng, Y; Suksamrarn, A; Wang, F; Wang, J; Wei, X; Wisanwattana, W; Wu, W; Zeng, Z; Zhang, G; Zhang, J; Zhu, Q | 1 |
| Chen, M; Du, X; Liu, W; Liu, X; Xing, B; Zhang, C | 1 |
| Balbi, E; Cardoso, SW; Carius, L; Grinsztejn, B; Halpern, M; Pacheco, L; Perazzo, H; Pinto, L; Roma, J; Veloso, VG | 1 |
| Chen, J; Cheng, R; Deng, W; Gai, X; Gu, S; Liu, F; Shang, K; Tang, B; Wu, X; Wu, Y; Zhang, B; Zhang, H; Zhang, Z; Zhao, N; Zheng, L | 1 |
| Castelli, S; Ciccarone, F; Ciriolo, MR; De Falco, P; Desideri, E; Felice, F; Lazzarino, G; Salvatori, I | 1 |
| Cao, Z; Cui, J; Gao, X; Guan, W; Han, X; Li, J; Liu, Y; Tong, M; Wang, H; Xian, X; Zhao, L | 1 |
| Cheng, YT; Ding, YZ; Ji, LX; Ma, YZ; Meng, LQ; Xue, L; Zhu, T | 1 |
| Bittaye, SO; Fatty, G; Jallow, MS; Jatta, A; Jeng, A; Kambi, A; Leigh, O; Njie, R; Sanneh, L; Sisawo, MM; Tamba, S; Tekanyi, MAI | 1 |
| Kao, JH; Wai-Sun Wong, V | 1 |
| Fang, JC; Li, C; Li, XZ; Li, Z; Li, ZC; Liang, CY; Zhao, YN | 1 |
| Hao, X; Li, W | 1 |
| Jiang, C; Ma, H | 1 |
| Li, RQ; Liu, W; Pan, W; Song, HQ; Xu, FJ; Yang, M; Yu, B | 1 |
| Convertini, P; Dituri, F; Giannelli, G; Iacobazzi, V; Infantino, V; Mancarella, S; Palmieri, F; Santarsiero, A; Todisco, S | 1 |
| Gao, YJ; Jin, B; Li, HW; Liu, ZW; Ma, XM; Meng, FP; Su, HB; Zhang, M; Zhao, JM | 1 |
| Basu, SS; Blair, IA; Clarke-Katzenberg, RH; Darpolor, MM; Glickson, JD; Kaplan, DE; Nelson, DS; Worth, A | 1 |
| Hirano, E; Inoue, S; Morinaga, T; Sato, Y; Yamaguchi, Y; Yamamoto, K | 1 |
| MORRIS, HP; WAGLE, SR; WEBER, G | 1 |
| LORINCZ, AB; RYAN, WL | 1 |
| ABOOBAKER, VS; APTE, BK; JAYARAMAN, R; SAHASRABUDHE, MB | 1 |
| Dávid, K; Horváth, G | 1 |
| Abe, H; Endo, Y; Hanasawa, K; Kurumi, Y; Morikawa, S; Naitoh, H; Naka, S; Shiomi, H; Tani, T; Umeda, T | 1 |
| Kemeny, NE; Leonard, GD | 1 |
| Dowdall, S; Gilmore, I; Goldring, CE; Jenkins, R; Kitteringham, NR; Lian, LY; Owen, A; Palmer, L; Park, BK | 1 |
| Faruqi, A; Shih, C; Shih, JW; Yuan, TT | 1 |
| Christensen, S; Finkelstein, SD; Sayegh, R; Swalsky, PA | 1 |
| Fidge, N; Pyle, L; Sviridov, D | 1 |
| Blomgren, H; Ragnhammar, P | 1 |
| Conner, EA; Wirth, PJ | 1 |
| Köhne, CH; Schmoll, HJ; Schöffski, P; Wilke, H | 1 |
| McGivan, JD | 1 |
| Brady, F; Brown, G; Harte, RJ; Jones, T; Luthra, SJ; Matthews, JC; O'Reilly, SM; Osman, S; Price, PM; Tilsley, DW | 1 |
| Bagaglio, JF; Mokotoff, M; Parikh, BS | 1 |
| Jackson, RC; Morris, HP; Weber, G | 2 |
| Funakoshi, I; Nakada, H; Yamashina, I | 1 |
| Greenhouse, WV; Lehninger, AL | 1 |
| Graff, JC; Plagemann, PG | 1 |
| Clark, AW; Rudolph, FB | 1 |
| Keppler, DD | 1 |
| Nishimura, S; Okada, N; Shindo-Okada, N | 1 |
| Matsuno, T | 1 |
| Eisenberg, BL; Fowler, WC; Hoffman, JP | 1 |
| Costa, P; Kemeny, N; Kurtz, RC; Martin, D; Murray, M; Niedzwiecki, D; Seiter, K; Urmacher, C | 1 |
| Berman, P; Black, D; Cohen, L; Fairbanks, LD; Harley, EH; Sacks, S; Simmonds, HA | 1 |
| Gottschalk, A; Hoffer, PB | 1 |
| Bergenstal, R; Burg, A; Cooney, DA; Fleischman, R; Morrison, R; Yavelow, J; Zlotoff, R | 1 |
| Cohen, L; Eagle, H; Levy, M; Washington, CL | 1 |
| Bresnick, E; Lyman, K; Mayfield, ED | 1 |
| Orr, GR; Patterson, MK | 2 |
| Efskind, J; Eker, P; Fritzson, P; Spaeren, U | 1 |
| Plagemann, PG | 1 |
| Bhide, SV | 1 |
| Maley, F; Maley, GF | 1 |
| Chou, TC; Handschumacher, RE | 1 |
| Briscoe, WT; Duff, R; Griffin, AC; Rapp, F; Taylor, W | 1 |
| Shigesada, K; Tatibana, M | 1 |
| Fasce, CF; Rej, R; Vanderlinde, RE | 1 |
5 review(s) available for aspartic acid and Cancer of Liver
| Article | Year |
|---|---|
[Iron storage disease].
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Chromosomes, Human, Pair 6; Cysteine; Diabetes Mellitus; Diagnosis, Differential; Hemochromatosis; Histidine; Humans; Hyperpigmentation; Iron Overload; Liver Cirrhosis; Liver Neoplasms; Mass Screening; Phlebotomy; Point Mutation; Population Surveillance; Prevalence; Prognosis; Tyrosine | 2004 |
How to optimize the effect of 5-fluorouracil modulated therapy in advanced colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Fluorouracil; Humans; Interferons; Leucovorin; Liver Neoplasms; Methotrexate; Phosphonoacetic Acid | 1995 |
The dead end of 5-fluorouracil double modulation and promise of continuous infusion schedules in the treatment of metastatic colorectal cancer.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Combined Modality Therapy; Dipyridamole; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Humans; Immunologic Factors; Infusions, Intravenous; Injections, Intravenous; Interferons; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Proteins; Nucleotides; Palliative Care; Phosphonoacetic Acid; Randomized Controlled Trials as Topic; Thymidylate Synthase | 1996 |
Tumor scanning agents.
Topics: Antibodies, Neoplasm; Aspartic Acid; Bismuth; Bleomycin; Carbon Radioisotopes; Carcinoembryonic Antigen; Carcinoma, Hepatocellular; Cobalt Radioisotopes; Gallium; Hodgkin Disease; Humans; Indium; Iodine Radioisotopes; Liver Neoplasms; Lymphoma; Mediastinal Neoplasms; Melanoma; Methionine; Neoplasms; Radionuclide Imaging; Selenium; Serum Albumin; Tonsillar Neoplasms | 1974 |
Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Carcinoma, Hepatocellular; Dietary Proteins; Glutamates; Humans; Liver; Liver Neoplasms; Magnesium; Mice; Models, Chemical; Neurospora; Phosphotransferases; Pyrimidines; Rats; Spleen; Transferases; Uracil Nucleotides; Urea | 1972 |
1 trial(s) available for aspartic acid and Cancer of Liver
| Article | Year |
|---|---|
A new syndrome: ascites, hyperbilirubinemia, and hypoalbuminemia after biochemical modulation of fluorouracil with N-phosphonacetyl-L-aspartate (PALA)
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Aspartic Acid; Colorectal Neoplasms; Drug Evaluation; Fluorouracil; Humans; Hyperbilirubinemia; Liver Neoplasms; Male; Phosphonoacetic Acid; Prothrombin Time; Retrospective Studies; Serum Albumin; Syndrome; Transaminases | 1991 |
53 other study(ies) available for aspartic acid and Cancer of Liver
| Article | Year |
|---|---|
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming.
Topics: Antineoplastic Agents; Bibenzyls; Carcinoma, Hepatocellular; Cell Proliferation; Click Chemistry; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Oxidative Stress; Phenol; Pyruvate Carboxylase; Structure-Activity Relationship | 2022 |
Long noncoding RNA LINC01234 promotes hepatocellular carcinoma progression through orchestrating aspartate metabolic reprogramming.
Topics: Animals; Argininosuccinate Synthase; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mammals; Mice; Mice, Nude; RNA, Long Noncoding | 2022 |
Effectiveness of Direct-acting Agents After Liver Transplantation A Real-life Study in Rio de Janeiro.
Topics: Antiviral Agents; Aspartic Acid; Biomarkers; Brazil; Carcinoma, Hepatocellular; Female; Hepacivirus; Hepatitis C; Humans; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Retrospective Studies; Ribavirin; RNA; Transaminases | 2022 |
Oncogenic β-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.
Topics: Animals; Aspartic Acid; beta Catenin; Carcinogenesis; Dihydroorotase; Drug Delivery Systems; Ligases; Liver Neoplasms; Mice; Nucleotides; Phosphates; Proto-Oncogene Proteins c-akt; Pyrimidines | 2022 |
Hindering NAT8L expression in hepatocellular carcinoma increases cytosolic aspartate delivery that fosters pentose phosphate pathway and purine biosynthesis promoting cell proliferation.
Topics: Acetyltransferases; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Humans; Liver Neoplasms; Mice; Mitochondrial Membrane Transport Proteins; Pentose Phosphate Pathway; Purines | 2023 |
Effects of Scutellaria strigillosa Hemsl. extract on HepG2 cell proliferation and apoptosis through binding to aspartate β-hydroxylase.
Topics: Apoptosis; Aspartic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Hep G2 Cells; Humans; Liver Neoplasms; Mixed Function Oxygenases; Molecular Docking Simulation; Plant Extracts; Scutellaria | 2023 |
[Moxibustion with seed-size moxa cone enhances anti-tumor effect of cyclophosphamide on Hepa1-6 hepatoma-bearing mice by regulating apoptosis factor cysteine family].
Topics: Animals; Apoptosis; Aspartic Acid; Body Weight; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cyclophosphamide; Cysteine; Interleukin-2; Interleukin-4; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Moxibustion; Quality of Life; RNA, Messenger; Tumor Necrosis Factor-alpha | 2023 |
Clinical manifestation, staging and prognosis of hepatocellular carcinoma in Gambian patients.
Topics: Abdominal Pain; Adult; Aspartic Acid; Carcinoma, Hepatocellular; Female; Gambia; Hepatitis B Surface Antigens; Humans; Liver Neoplasms; Male; Prognosis | 2023 |
Letter: elevated aspartate aminotransferase and aspartate aminotransferase to alanine aminotransferase ratio predicts poor survival in hepatocellular carcinoma after resection-Authors' reply.
Topics: Alanine Transaminase; Asia, Eastern; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Hepatocellular; Expert Testimony; Hepatitis B, Chronic; Humans; Liver Neoplasms | 2020 |
Letter: elevated aspartate aminotransferase and aspartate aminotransferase to alanine aminotransferase ratio predicts poor survival in hepatocellular carcinoma after resection.
Topics: Alanine Transaminase; Asia, Eastern; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Hepatocellular; Expert Testimony; Hepatitis B, Chronic; Humans; Liver Neoplasms | 2020 |
Molybdenum Dioxide (MoS₂)/Gadolinium (Gd) Containing Arginine-Glycine-Aspartic Acid (RGD) Sequences as New Nano-Contrast Agent for Cancer Magnetic Resonance Imaging (MRI).
Topics: Animals; Arginine; Aspartic Acid; Carcinoma, Hepatocellular; Contrast Media; Gadolinium; Glycine; Liver Neoplasms; Magnetic Resonance Imaging; Mice; Mice, Nude; Molybdenum; Nanoparticles; Oligopeptides; Oxides | 2021 |
Dehydroascorbic Acid and pGPMA Dual Modified pH-Sensitive Polymeric Micelles for Target Treatment of Liver Cancer.
Topics: Acrylamides; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Dehydroascorbic Acid; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Mice; Mice, Nude; Micelles; Paclitaxel; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley | 2018 |
Rodlike Supramolecular Nanoassemblies of Degradable Poly(Aspartic Acid) Derivatives and Hydroxyl-Rich Polycations for Effective Delivery of Versatile Tumor-Suppressive ncRNAs.
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Gene Transfer Techniques; Genetic Vectors; Humans; Liver Neoplasms; Nanoparticles; Peptides; Polyamines; Polyelectrolytes; RNA, Long Noncoding; RNA, Untranslated | 2018 |
Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma.
Topics: Amino Acid Transport Systems, Acidic; Antiporters; Aspartic Acid; Brain; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Glutamic Acid; Heart; Hep G2 Cells; Humans; Liver Neoplasms; Mitochondrial Membrane Transport Proteins; Muscle, Skeletal; Protein Isoforms; Up-Regulation | 2019 |
Clinical-pathological analysis of hepatitis B virus recurrence after liver transplantation in Chinese patients.
Topics: Adult; Age Factors; Antiviral Agents; Aspartic Acid; Carcinoma, Hepatocellular; China; DNA, Viral; Drug Therapy, Combination; End Stage Liver Disease; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Immunoglobulins; Lamivudine; Liver Neoplasms; Liver Transplantation; Male; Methionine; Middle Aged; Mutation; Retrospective Studies; Risk Factors; Secondary Prevention; Sex Factors; Tyrosine | 2014 |
The aspartate metabolism pathway is differentiable in human hepatocellular carcinoma: transcriptomics and (13) C-isotope based metabolomics.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Aspartic Acid; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatography, Liquid; Humans; Lactic Acid; Liver; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Phosphates; Phosphatidylethanolamines; Principal Component Analysis; Succinic Acid; Transcriptome | 2014 |
Combination of aspartic acid and glutamic acid inhibits tumor cell proliferation.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamic Acid; Humans; Liver Neoplasms; Placenta; Pregnancy; Proto-Oncogene Proteins c-akt; Rabbits; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES.
Topics: Alanine; Amino Acids; Aspartic Acid; Carcinoma, Hepatocellular; Glycine; Histocytochemistry; Isoleucine; Liver Neoplasms; Liver Regeneration; Mice; Neoplasms, Experimental; Proteins; Research; Serine; Valine | 1963 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
Partial deletion of aspartic acid from DNA-proteins during butter yellow carcinogenesis.
Topics: Aspartic Acid; Carcinogenesis; Carcinogens; DNA; Liver; Liver Neoplasms; Neoplasms; Nucleoproteins; p-Dimethylaminoazobenzene | 1962 |
Open-configuration MR-guided microwave thermocoagulation therapy for metastatic liver tumors from breast cancer.
Topics: Adult; Aged; Alanine Transaminase; Aspartic Acid; Breast Neoplasms; Electrocoagulation; Female; Humans; Image Processing, Computer-Assisted; Liver Neoplasms; Magnetic Resonance Imaging; Microwaves; Middle Aged | 2005 |
Continued survival of more than ten years, without resection of metastatic disease, in patients with metastatic colorectal cancer treated with biomodulated fluorouracil: report of two cases.
Topics: Acetates; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Humans; Immunologic Factors; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Phosphonoacetic Acid; Remission Induction; Uridine; Vitamin B Complex | 2006 |
Detection and biochemical characterisation of a novel polymorphism in the human GSTP1 gene.
Topics: Alleles; Amino Acid Substitution; Aspartic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Circular Dichroism; Dinitrochlorobenzene; Escherichia coli; Gene Frequency; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Kinetics; Liver Diseases, Alcoholic; Liver Neoplasms; Models, Molecular; Polymorphism, Genetic; Protein Structure, Secondary; Recombinant Proteins; Temperature | 2007 |
The mechanism of natural occurrence of two closely linked HBV precore predominant mutations.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Calorimetry; Carcinoma, Hepatocellular; Cell Line; Codon; DNA Primers; DNA, Viral; Geography; Glycine; Growth Hormone; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver Neoplasms; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Point Mutation; Protein Precursors; Recombinant Proteins; RNA, Viral; Transfection; Tumor Cells, Cultured; Virus Replication | 1995 |
Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type.
Topics: Adenine; Adenocarcinoma; Aspartic Acid; Biology; Codon; Colonic Neoplasms; Gene Frequency; Genes, ras; Genotype; Guanine; Humans; Liver Neoplasms; Lymphatic Metastasis; Mutation; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Rectal Neoplasms | 1993 |
Identification of a sequence of apolipoprotein A-I associated with the efflux of intracellular cholesterol to human serum and apolipoprotein A-I containing particles.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Apolipoprotein A-I; Arginine; Aspartic Acid; Binding Sites; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cell Membrane; Cholesterol; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Epitopes; Humans; Immunoglobulin Fab Fragments; Kinetics; Lipoproteins, HDL; Liposomes; Liver Neoplasms; Membrane Lipids; Phosphatidylcholines; Tumor Cells, Cultured | 1996 |
Protein alterations associated with gene amplification in cultured human and rodent cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; CHO Cells; Cricetinae; Dihydroorotase; Drug Resistance; Electrophoresis, Gel, Two-Dimensional; Gene Amplification; Growth Inhibitors; Humans; Infant; Ligases; Liver Neoplasms; Phosphonoacetic Acid; Proteins; RNA, Messenger; Silver Staining; Tumor Cells, Cultured | 1996 |
Rat hepatoma cells express novel transport systems for glutamine and glutamate in addition to those present in normal rat hepatocytes.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glutamine; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Weight; Rats; Sodium; Symporters | 1998 |
Tumor, normal tissue, and plasma pharmacokinetic studies of fluorouracil biomodulation with N-phosphonacetyl-L-aspartate, folinic acid, and interferon alfa.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Area Under Curve; Aspartic Acid; Colorectal Neoplasms; Drug Interactions; Female; Fluorouracil; Humans; Interferon-alpha; Leucovorin; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasms; Phosphonoacetic Acid; Regional Blood Flow; Stomach Neoplasms; Tomography, Emission-Computed | 1999 |
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Hydroxy Acids; Ligases; Liver Neoplasms; Male; Molecular Conformation; Neoplasms, Experimental; Rats; Stereoisomerism; Structure-Activity Relationship | 1975 |
Neoplastic transformation-linked alterations in adenylosuccinate synthetase activity.
Topics: Aging; Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Inosine Nucleotides; Kidney; Kidney Neoplasms; Ligases; Liver; Liver Neoplasms; Liver Regeneration; Male; Rats | 1975 |
The isolation and characterization of glycopeptides and mucopolysaccharides from plasma membranes of an ascites hepatoma, AH 130.
Topics: Animals; Aspartic Acid; Carcinoma, Hepatocellular; Cell Membrane; Female; Glycopeptides; Glycosaminoglycans; Heparitin Sulfate; Hexosamines; Hexoses; Liver Neoplasms; Rats; Serine; Sialic Acids; Sulfuric Acid Esters; Threonine | 1975 |
Occurrence of the malate-aspartate shuttle in various tumor types.
Topics: Aminooxyacetic Acid; Animals; Antimycin A; Aspartic Acid; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Krebs 2; Cell Line; Cyanides; Kinetics; Lactates; Leukemia L1210; Liver Neoplasms; Malates; Malonates; Mitochondria; NAD; Neoplasms, Experimental; Oxidation-Reduction; Pyruvates; Rotenone; Tricarboxylic Acids | 1976 |
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Glucose; Hypoxanthines; Inosine Nucleotides; Liver Neoplasms; Mengovirus; Neoplasm Proteins; Neoplasms, Experimental; Nitroso Compounds; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Neoplasm; Succinates; Uracil Nucleotides; Uridine | 1976 |
Regulation of purine metabolism. Adenylosuccinate synthetase from Novikoff ascites tumor cells.
Topics: Adenosine Monophosphate; Animals; Anti-Bacterial Agents; Aspartic Acid; Carcinoma, Hepatocellular; Feedback; Guanosine Triphosphate; Inosine Nucleotides; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Rats | 1976 |
Aspartate carbamoyltransferase inhibition and uridylate trapping result in a synergistic depression of uridine triphosphate in hepatoma cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Female; Galactosamine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Organophosphonates; Rats; Uracil Nucleotides | 1977 |
Isolation of mammalian tRNAAsp and tRNATyr by lectin-Sepharose affinity column chromatography.
Topics: Animals; Aspartic Acid; Carcinoma, Hepatocellular; Chromatography, Affinity; Concanavalin A; Liver; Liver Neoplasms; Neoplasms, Experimental; Rabbits; Rats; RNA, Transfer; Sepharose; Tyrosine | 1977 |
Enzymes of the purine ribonucleotide cycle in rat hepatomas and kidney tumors.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Animals; Animals, Newborn; Antimetabolites; Aspartic Acid; Carcinoma, Hepatocellular; Fasting; In Vitro Techniques; Inosine Nucleotides; Isoenzymes; Kidney; Kidney Neoplasms; Kinetics; Ligases; Liver; Liver Neoplasms; Liver Regeneration; Lyases; Male; Muscles; Neoplasms, Experimental; Nucleotide Deaminases; Purine Nucleotides; Rats; Succinates | 1977 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in HuH13 human hepatoma cells.
Topics: Aspartic Acid; Carcinoma, Hepatocellular; Cytosol; Humans; Kinetics; Liver Neoplasms; Malates; NAD; Oxidation-Reduction; Tumor Cells, Cultured | 1992 |
Hepatic resection following systemic chemotherapy for metastatic colorectal carcinoma.
Topics: Aged; Antineoplastic Agents; Aspartic Acid; Colorectal Neoplasms; Female; Fluorouracil; Hepatectomy; Humans; Leucovorin; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Phosphonoacetic Acid; Retrospective Studies; Time Factors | 1992 |
Source and fate of circulating pyrimidines.
Topics: Aspartic Acid; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Liver; Liver Neoplasms; Orotic Acid; Pyrimidines; Radioisotope Dilution Technique | 1986 |
Azotomycin--toxicologic, biochemical and pharmacologic studies in mice.
Topics: Animals; Antibiotics, Antineoplastic; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Ataxia; Azo Compounds; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Diarrhea; DNA; Formates; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Lethal Dose 50; Ligases; Liver Neoplasms; Malate Dehydrogenase; Mice; Mice, Inbred Strains; Protein Biosynthesis; Seizures; Spleen; Time Factors | 1974 |
The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize. II. Glutamic acid and glutamine; aspartic acid and asparagine.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Culture Techniques; Glucose; Glutamates; Glutamine; Liver Neoplasms; Rats; Sarcoma, Experimental | 1966 |
Incorporation of bicarbonate-14 C into pyrimidines and into ribonucleic acid of the Novikoff ascites tumor cell.
Topics: Ammonia; Animals; Aspartic Acid; Bicarbonates; Carcinoma, Hepatocellular; Chromatography, Ion Exchange; Diazooxonorleucine; Glutamine; In Vitro Techniques; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Rats; RNA, Neoplasm; Uracil Nucleotides | 1967 |
Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonium Chloride; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Carcinoma, Hepatocellular; Diphosphates; Female; Glutamine; Hydrogen-Ion Concentration; Hydroxamic Acids; Hydroxylamines; Liver Neoplasms; Magnesium; Manganese; Neoplasms, Experimental; Potassium; Rats | 1968 |
Effect of dietary 2-acetylaminofluorene on rat liver enzymes involved in the anabolism and catabolism of nucleic acid precursors.
Topics: Animals; Aspartic Acid; Carcinogens; Diet; Female; Liver; Liver Neoplasms; N-Glycosyl Hydrolases; Nucleic Acids; Nucleotidases; Phosphoric Monoester Hydrolases; Phosphotransferases; Precancerous Conditions; Rats; Transferases | 1968 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Culture Media; Culture Techniques; Diffusion; DNA; Electrophoresis; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic Acid; Rats; RNA; Thymidine; Time Factors; Tritium; Uracil; Uridine | 1971 |
Comparative study of metabolic profiles of primary hepatoma, regenerating liver, and liver in newborn Swiss mice.
Topics: Acetates; Aldehyde-Lyases; Amides; Animals; Animals, Newborn; Aspartic Acid; Carbamates; Carcinoma, Hepatocellular; Fructose-Bisphosphatase; Glucose-6-Phosphatase; Lactates; Liver; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Mice; Neoplasms, Experimental; Ornithine Carbamoyltransferase; Phosphoric Monoester Hydrolases; Transferases | 1971 |
The apparent induction of thymidylate synthetase by amethopterin.
Topics: Animals; Aspartic Acid; Benzoates; Carcinoma, Hepatocellular; Enzyme Induction; Folic Acid; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Methotrexate; Methyltransferases; Neoplasms, Experimental; Quinazolines; Rats; Thymine Nucleotides; Uracil Nucleotides | 1971 |
Production of L-asparagine by tumor cells and the effect of asparagine analogs.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Azo Compounds; Bromine; Carbon Isotopes; Carcinoma, Hepatocellular; Chlorine; Glutamine; Kinetics; Leukemia, Experimental; Liver Neoplasms; Lymphoma, Non-Hodgkin; Mast Cells; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma 180 | 1972 |
Aspartyl transfer RNA profiles in normal and cancer cells.
Topics: Animals; Ascites; Aspartic Acid; Breast Neoplasms; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Transformation, Neoplastic; Chromatography; Chromatography, DEAE-Cellulose; Cricetinae; Humans; Liver; Liver Neoplasms; Methods; Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred Strains; RNA, Transfer; Simian virus 40; Tritium | 1972 |
Increased aspartate aminotransferase activity of serum after in vitro supplementation with pyridoxal phosphate.
Topics: Adult; Aspartate Aminotransferases; Aspartic Acid; Carcinoma, Squamous Cell; Colorimetry; Cytoplasm; Dose-Response Relationship, Drug; Drug Stability; Erythrocytes; Evaluation Studies as Topic; Female; Glutamate Dehydrogenase; Humans; Kinetics; Liver Neoplasms; Male; Methods; Middle Aged; Pyridoxal Phosphate; Regression Analysis; Renal Dialysis; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Regeneration, tumor, dietary, and L-asparaginase effects on asparagine biosynthesis in rat liver.
Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Escherichia coli; Female; Ligases; Liver; Liver Neoplasms; Liver Regeneration; Nutritional Requirements; Organ Size; Rats; Spleen | 1969 |