Compounds > aspartic acid
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aspartic acid and Breast Cancer

aspartic acid has been researched along with Breast Cancer in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199012 (21.82)18.7374
1990's11 (20.00)18.2507
2000's9 (16.36)29.6817
2010's16 (29.09)24.3611
2020's7 (12.73)2.80

Authors

AuthorsStudies
Chen, M; Fu, D; Huang, X; Lv, Z; Su, D; Zhang, W; Zhang, Y1
Li, J; Lin, Y; Luo, Y; Qu, Z; Sun, Y; Yang, Z; Zhang, L; Zhang, X1
Barboro, P; Boccardo, F; Grillo, F; Mastracci, L; Poddine, S; Rubagotti, A1
Bhattacharya, N; Chakrabarty, D; Kolvekar, N; Mondal, S; Sarkar, A1
Chen, C; Li, Z; Liu, T; Ye, L; Yi, J1
Beyer, J; Cerhan, JH; Couch, R; Kantarci, K; Kara, F; Kohli, S; Lesnick, TG; Novotny, PJ; Pruthi, S; Ruddy, KJ; Tosakulwong, N; Zeydan, B1
Cao, D; Chen, C; Chen, L; Chen, X; Hu, X; Kong, F; Li, J; Li, X; Liu, O; Liu, S; Luo, J; Luo, T; Luo, W; Luo, Z; Ma, D; Ming, Z; Peng, K; Wen, M; Xia, L; Xie, Y; Xu, N; Yang, C; Yi, W; Zou, Z1
Cheng, R; Li, X; Liu, J; Liu, Z; Sun, N; Tian, Z; Yang, Z; Zhao, C1
Clish, CB; Haigis, MC; Jeanfavre, S; Ringel, AE; Spinelli, JB; Yoon, H1
Chen, BB; Chen, TW; Cheng, AL; Lin, CH; Lu, YS; Shih, TT; Wei, SY; Yu, CW1
Bellvert, F; Bertero, T; Boulter, E; Bourget, I; Bozec, A; Bulavin, DV; Chan, SY; Estrach, S; Feral, CC; Gaggioli, C; Grasset, EM; Hofman, P; Meneguzzi, G; Oldham, WM; Pisano, S1
Chen, J; Fan, J; Hong, R; Li, J; Wang, S; Wang, Y; Wu, M; Xia, W; Xia, X; Xu, F; Zhan, Q; Zhang, K; Zhang, W1
Babu, PV; Chitkara, D; Khurana, RK; Kumar, V; Raza, K; Sharma, S; Singh, B; Thotakura, N1
Bacci, M; Bianchini, F; Cappellesso, F; Chiarugi, P; Comito, G; Ferracin, M; Gao, Q; Giannoni, E; Ippolito, L; Lorito, N; Luti, S; Marangoni, E; Martin, LA; Mazzone, M; Morandi, A; Parri, M; Ramazzotti, M; Romagnoli, S; Simões, BM; Virga, F1
Ben-Baruch, N; Brown, M; Dvir, A; Jeselsohn, R; Klein, B; Merenbakh-Lamin, K; Miller, VA; Rizel, S; Rubinek, T; Sarid, D; Soussan-Gutman, L; Wolf, I; Yeheskel, A; Yelensky, R1
Foerster, B; Harris, RE; Ichesco, E; Khabir, T; Sen, A; Wood, L; Wright, B; Zick, SM; Zwickey, H1
Asano, T; Dong, Y; Endo, Y; Fujii, Y; Hato, Y; Sato, S; Takahashi, S; Toyama, T; Yamashita, H; Yoshimoto, N1
Curpan, R; Jordan, VC; Maximov, PY1
Garmire, L; Jia, W; Qiu, Y; Shvetsov, YB; Xie, G; Yen, Y; Yu, H; Zhao, A; Zhao, X; Zhou, B1
Badawi, A; Collery, P; Desmaële, D; Hassan, RE; Jeannesson, P; Mohsen, A; Morjani, H; Sabry, GM; Saby, C1
Ansari, IH; Burant, CF; El Azzouny, M; Jitrapakdee, S; Longacre, MJ; MacDonald, MJ; Phannasil, P; Rattanapornsompong, K1
Choi, HG; Kim, JO; Ramasamy, T; Ruttala, HB; Shin, BS; Yong, CS1
Avvedimento, EV; Coppa, A; D'Inzeo, S; Di Domenico, M; Di Zazzo, E; Donini, CF; Nicolussi, A; Porcellini, A; Zuchegna, C1
Subrata, S; Ying, H1
LORINCZ, AB; RYAN, WL1
Balasubramanian, SP; Bhattacharyya, NP; Cox, A; Healey, CS; MacPherson, G; Meuth, M; Pharoah, PD; Ponder, BA; Reed, MW; Teare, MD1
Abe, H; Endo, Y; Hanasawa, K; Kurumi, Y; Morikawa, S; Naitoh, H; Naka, S; Shiomi, H; Tani, T; Umeda, T1
Bermejo, JL; Bugert, P; Burwinkel, B; Frank, B; Hemminki, K; Klaes, R; Schmutzler, RK; Wappenschmidt, B1
Alarid, ET; Fowler, AM; Solodin, NM; Valley, CC1
Esplin, ED; Evans, GA; Martinez, B; Mumby, MC; Ramos, P; Tomlinson, GE1
Galán, JJ; González-Mancha, R; González-Martín, A; Moreno-Nogueira, JA; Real, LM; Royo, JL; Ruiz, A1
Dyczynska, E; Sun, D; Syta, E; Zolkiewska, A1
Cocconi, G; Heuson, JC; Mouridsen, HT; Palshof, T; Paridaens, R; Rotmensz, N; Rozencweig, M; Sylvester, R; Van Oosterom, A1
Ardalan, B; Jamin, D; Jayaram, HN; Presant, CA1
Ervin, TJ; Kufe, DW; Meshad, MW; Weiss, GR1
Davis, TE; Falkson, G; Keller, AM; Taylor, SG1
Ardalan, B; Cooney, DA; Glazer, RI; Jayaram, HN; Kensler, TW; Macdonald, JS; Van Pham, T1
Oudkerk, M; Sijens, PE; van Dijk, P1
Cleaveland, ES; Cooney, DA; Ford, H; Kelley, JA; Paull, K; Zaharevitz, DW1
Cowan, KH; Gudas, JM; Li, T; Nguyen, H; Robey, R; Sadzewicz, L; Wosikowski, K1
Brown, MS; Cagnoni, PJ; Jones, RB; Sheeder, JL; Simon, JH; Stears, JC; Stemmer, SM1
Jordan, VC; Levenson, AS1
Paranavitana, CM1
Alba, F; Cueva, C; Martínez, JM; Prieto, I; Ramírez, M; Ramírez, MJ1
Pham, HT; Ruediger, R; Walter, G1
Hamaguchi, T; Hrushesky, WJ; Kakizoe, T; Kataoka, K; Kawaguchi, T; Matsumura, Y; Mizumura, Y; Moriyasu, F; Nishiyama, N1
Blank, EW; Ceriani, RL; Pant, KD; Santos, O1
Ardalan, B; Benedetto, P; Feun, L; Fodor, M; Livingstone, A; Morrell, L; Richman, S; Savaraj, N; Sridhar, KS; Waldman, S1
Allegra, CJ1
Chisena, CA; Cowan, KH; Cysyk, RL; Karle, JM1
Buzdar, AU; Hortobagyi, GN; Mann, GB; Valdivieso, M; Yap, HY1
Briscoe, WT; Duff, R; Griffin, AC; Rapp, F; Taylor, W1
Daill, M; Fink, E; Kronberger, L; Schindler, R1
Fink, E; Kronberger, L1
Nieper, A1

Trials

2 trial(s) available for aspartic acid and Breast Cancer

ArticleYear
A phase I, II study of high-dose 5-fluorouracil and high-dose leucovorin with low-dose phosphonacetyl-L-aspartic acid in patients with advanced malignancies.
    Cancer, 1991, Sep-15, Volume: 68, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Breast Neoplasms; Drug Evaluation; Female; Fluorouracil; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Humans; Leucovorin; Lung Neoplasms; Male; Middle Aged; Neoplasms; Phosphonoacetic Acid; Prognosis

1991
A comparative study of PALA, PALA plus 5-FU, and 5-FU in advanced breast cancer.
    Cancer, 1985, Sep-15, Volume: 56, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Breast Neoplasms; Female; Fluorouracil; Humans; Middle Aged; Neoplasm Metastasis; Organophosphorus Compounds; Phosphonoacetic Acid; Random Allocation

1985

Other Studies

53 other study(ies) available for aspartic acid and Breast Cancer

ArticleYear
Ultrasound and magnetic resonance imaging of cyclic arginine glycine aspartic acid-gadopentetic acid-polylactic acid in human breast cancer by targeting αvβ3 in xenograft-bearing nude mice.
    Bioengineered, 2022, Volume: 13, Issue:3

    Topics: Animals; Arginine; Aspartic Acid; Breast Neoplasms; Contrast Media; Female; Gadolinium DTPA; Glycine; Heterografts; Humans; Magnetic Resonance Imaging; Mice; Mice, Nude; Polyesters

2022
Effects of glutamate and aspartate on prostate cancer and breast cancer: a Mendelian randomization study.
    BMC genomics, 2022, Mar-16, Volume: 23, Issue:1

    Topics: Adult; Aspartic Acid; Breast Neoplasms; Glutamic Acid; Humans; Male; Mendelian Randomization Analysis; Prostatic Neoplasms

2022
The prognostic value of aspartate beta-hydroxylase in early breast cancer.
    The International journal of biological markers, 2022, Volume: 37, Issue:3

    Topics: Aspartic Acid; Breast Neoplasms; Calcium-Binding Proteins; Cohort Studies; Female; Humans; Mixed Function Oxygenases; Muscle Proteins; Prognosis

2022
SPAD-1, a serine proteinase associated disintegrin from Russell's viper venom disrupts adhesion of MCF7 human breast cancer cells.
    Toxicon : official journal of the International Society on Toxinology, 2023, Jan-01, Volume: 221

    Topics: Animals; Aspartic Acid; Breast Neoplasms; Daboia; Disintegrins; Female; Fibronectins; Histidine; Humans; Laminin; MCF-7 Cells; Serine Proteases; Viper Venoms

2023
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
    Breast cancer research and treatment, 2023, Volume: 201, Issue:3

    Topics: Apoptosis; Aspartic Acid; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Triple Negative Breast Neoplasms

2023
Longitudinal cognitive function and brain metabolites in women receiving chemotherapy for stage 1 to 3 breast cancer: Observational study.
    Medicine, 2023, Oct-20, Volume: 102, Issue:42

    Topics: Aspartic Acid; Brain; Breast Neoplasms; Choline; Cognition; Creatine; Female; Gyrus Cinguli; Humans

2023
Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor.
    Nature communications, 2021, 04-15, Volume: 12, Issue:1

    Topics: Adult; Aged; Animals; Argininosuccinate Synthase; Aspartic Acid; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citrulline; Citrullinemia; Enzyme Activators; Female; Gene Knockdown Techniques; Gene Knockout Techniques; HEK293 Cells; Humans; Macrolides; Metabolomics; Mice; Middle Aged; Molecular Docking Simulation; Mutation; Protein Binding; Pyrimidines; Recombinant Proteins; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2021
pH multistage responsive micellar system with charge-switch and PEG layer detachment for co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells.
    Biomaterials, 2017, Volume: 147

    Topics: Animals; Antineoplastic Agents; Aspartic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Curcumin; Drug Carriers; Drug Liberation; Drug Synergism; Female; Humans; Hydrogen-Ion Concentration; Imidazoles; Mice, Inbred BALB C; Micelles; Nanoparticles; Neoplastic Stem Cells; Paclitaxel; Particle Size; Polyethylene Glycols; Polyvinyls; Surface Properties

2017
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.
    Science (New York, N.Y.), 2017, 11-17, Volume: 358, Issue:6365

    Topics: Amination; Ammonia; Animals; Aspartic Acid; Biocatalysis; Breast Neoplasms; Cell Proliferation; Female; Glutamate Dehydrogenase; Humans; MCF-7 Cells; Mice; Proline; RNA, Small Interfering; Tumor Microenvironment

2017
Imaging biomarkers from multiparametric magnetic resonance imaging are associated with survival outcomes in patients with brain metastases from breast cancer.
    European radiology, 2018, Volume: 28, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Breast Neoplasms; Choline; Creatinine; Female; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Proportional Hazards Models; Prospective Studies

2018
Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.
    Cell metabolism, 2019, 01-08, Volume: 29, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Breast Neoplasms; Cancer-Associated Fibroblasts; Carcinoma; Cell Line; Extracellular Matrix; Female; Glutamic Acid; Head and Neck Neoplasms; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Trans-Activators; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins

2019
Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation.
    Molecular oncology, 2019, Volume: 13, Issue:4

    Topics: Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Biomarkers, Tumor; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Ketoglutaric Acids; Methotrexate; Mice; Middle Aged; Models, Biological; Phenotype; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Transcription, Genetic

2019
Aspartic acid tagged carbon nanotubols as a tool to deliver docetaxel to breast cancer cells: Reduced hemotoxicity with improved cytotoxicity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2019, Volume: 59

    Topics: Animals; Antineoplastic Agents; Aspartic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Drug Synergism; Humans; Nanotubes, Carbon; Rats, Wistar

2019
Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer.
    Cell reports, 2019, 07-02, Volume: 28, Issue:1

    Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Aspartic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Excitatory Amino Acid Transporter 2; Female; Gas Chromatography-Mass Spectrometry; GATA2 Transcription Factor; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Mice; Mice, Inbred BALB C; MicroRNAs; Neoplasm Metastasis; Prognosis; Transcriptome; Transplantation, Heterologous

2019
D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer.
    Cancer research, 2013, Dec-01, Volume: 73, Issue:23

    Topics: Amino Acid Substitution; Antineoplastic Agents, Hormonal; Aspartic Acid; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Glycine; Humans; MCF-7 Cells; Mutation, Missense; Tamoxifen

2013
Preliminary differences in peripheral immune markers and brain metabolites between fatigued and non-fatigued breast cancer survivors: a pilot study.
    Brain imaging and behavior, 2014, Volume: 8, Issue:4

    Topics: Aspartic Acid; Biomarkers; Brain; Breast Neoplasms; Creatine; Cross-Sectional Studies; Fatigue; Female; Glutamic Acid; Glutamine; Humans; Interleukin-6; Middle Aged; Phosphocreatine; Pilot Projects; Prognosis; Proton Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Severity of Illness Index; Survivors

2014
HER2 mutation status in Japanese HER2-negative breast cancer patients.
    Japanese journal of clinical oncology, 2014, Volume: 44, Issue:7

    Topics: Adult; Antineoplastic Agents; Asian People; Aspartic Acid; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Isoleucine; Japan; Methionine; Middle Aged; Molecular Targeted Therapy; Mutation; Neoplasm Grading; Polymerase Chain Reaction; Receptor, ErbB-2; Sequence Analysis, DNA; Tyrosine

2014
Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:6

    Topics: Aspartic Acid; Breast Neoplasms; Female; Heterografts; Humans; Mutation; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tyrosine

2015
Lowered circulating aspartate is a metabolic feature of human breast cancer.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Down-Regulation; Female; Humans; Metabolomics; Middle Aged; Young Adult

2015
Biological study of the effect of water soluble [N-(2-hydroxybenzyl)-L-aspartato] gallium complexes on breast carcinoma and fibrosarcoma cells.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2016, Volume: 21, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Breast Neoplasms; Caspase 3; Caspase 7; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fibrosarcoma; G2 Phase Cell Cycle Checkpoints; Gallium; Humans; M Phase Cell Cycle Checkpoints; Membrane Potential, Mitochondrial; Mitochondria; Organometallic Compounds; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Solubility; Water

2016
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:2

    Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine

2017
Layer-by-layer assembly of hierarchical nanoarchitectures to enhance the systemic performance of nanoparticle albumin-bound paclitaxel.
    International journal of pharmaceutics, 2017, Mar-15, Volume: 519, Issue:1-2

    Topics: Albumin-Bound Paclitaxel; Animals; Aspartic Acid; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Male; MCF-7 Cells; Nanoparticles; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Tissue Distribution

2017
The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration.
    International journal of oncology, 2012, Volume: 40, Issue:5

    Topics: Alanine; Animals; Antineoplastic Agents; Aspartic Acid; Breast Neoplasms; Cattle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Class Ia Phosphatidylinositol 3-Kinase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Humans; Mutation; Neoplasm Invasiveness; Phosphorylation; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Serine; Signal Transduction; src Homology Domains; Time Factors; Transfection; Tretinoin

2012
[S-phase arrest associated apoptosis leads to diversities of drug resistance and mutation rate in human breast cancer cells].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1999, Volume: 30, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Breast Neoplasms; Drug Resistance, Neoplasm; Humans; Phosphonoacetic Acid; Point Mutation; S Phase; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1999
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
Association of a common variant of the CASP8 gene with reduced risk of breast cancer.
    Journal of the National Cancer Institute, 2004, Dec-15, Volume: 96, Issue:24

    Topics: Aspartic Acid; Breast Neoplasms; Case-Control Studies; Caspase 10; Caspase 8; Caspases; England; Female; Genetic Predisposition to Disease; Genetic Variation; Heterozygote; Histidine; Homozygote; Humans; Odds Ratio; Polymorphism, Single Nucleotide; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor

2004
Open-configuration MR-guided microwave thermocoagulation therapy for metastatic liver tumors from breast cancer.
    Breast cancer (Tokyo, Japan), 2005, Volume: 12, Issue:1

    Topics: Adult; Aged; Alanine Transaminase; Aspartic Acid; Breast Neoplasms; Electrocoagulation; Female; Humans; Image Processing, Computer-Assisted; Liver Neoplasms; Magnetic Resonance Imaging; Microwaves; Middle Aged

2005
Re: Association of a common variant of the CASP8 gene with reduced risk of breast cancer.
    Journal of the National Cancer Institute, 2005, Jul-06, Volume: 97, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Breast Neoplasms; Case-Control Studies; Caspase 8; Caspases; Cohort Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Germany; Histidine; Humans; Middle Aged; Odds Ratio; Risk Assessment; Risk Factors

2005
Altered target gene regulation controlled by estrogen receptor-alpha concentration.
    Molecular endocrinology (Baltimore, Md.), 2006, Volume: 20, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Breast Neoplasms; Complement C3; Down-Regulation; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Leucine; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Transcription Factors; Transcriptional Activation; Up-Regulation; Uterus

2006
The glycine 90 to aspartate alteration in the Abeta subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function.
    Genes, chromosomes & cancer, 2006, Volume: 45, Issue:2

    Topics: Amino Acid Substitution; Aspartic Acid; Base Sequence; Breast Neoplasms; DNA Primers; Female; Genetic Vectors; Glycine; Humans; Immunoprecipitation; Lung Neoplasms; Male; Oligonucleotide Array Sequence Analysis; Pedigree; Phosphoprotein Phosphatases; Polymerase Chain Reaction; Polymorphism, Genetic; Protein Phosphatase 2

2006
Lack of association between NOS3 Glu298Asp and breast cancer risk: a case-control study.
    Breast cancer research and treatment, 2006, Volume: 100, Issue:3

    Topics: Aspartic Acid; Breast Neoplasms; Case-Control Studies; Female; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Glutamic Acid; Humans; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Risk Assessment; Risk Factors; Spain

2006
Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein.
    International journal of cancer, 2008, Jun-01, Volume: 122, Issue:11

    Topics: ADAM Proteins; ADAM12 Protein; Animals; Aspartic Acid; Biotinylation; Blotting, Western; Breast Neoplasms; Cell Movement; Female; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Histidine; Humans; Immunoprecipitation; Leucine; Membrane Proteins; Mice; Mutation; Phenylalanine

2008
N-(phosphonacetyl)-L-aspartate (PALA) in advanced breast cancer: a phase II trial of the EORTC breast cancer cooperative group.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aspartic Acid; Breast Neoplasms; Digestive System; Drug Eruptions; Drug Evaluation; Female; Humans; Infusions, Parenteral; Middle Aged; Neoplasm Metastasis; Organophosphorus Compounds; Phosphonoacetic Acid

1982
Phase I study of continuous-infusion PALA and 5-FU.
    Cancer treatment reports, 1984, Volume: 68, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartate Carbamoyltransferase; Aspartic Acid; Breast Neoplasms; Colonic Neoplasms; Diarrhea; Digestive System; Dose-Response Relationship, Drug; Drug Eruptions; Drug Evaluation; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Phosphonoacetic Acid

1984
Phase II trial of combination therapy with continuous-infusion PALA and bolus-injection 5-FU.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Infusions, Parenteral; Injections, Intravenous; Middle Aged; Organophosphorus Compounds; Pancreatic Neoplasms; Phosphonoacetic Acid; Sarcoma

1982
PALA in advanced breast cancer. A phase II pilot study by the ECOG.
    American journal of clinical oncology, 1982, Volume: 5, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Bone Marrow; Breast Neoplasms; Digestive System; Drug Evaluation; Female; Humans; Middle Aged; Mucous Membrane; Organophosphorus Compounds; Phosphonoacetic Acid; Skin; United States

1982
Synergistic effect of 5-fluorouracil and N-(phosphonacetyl)-L-aspartate on cell growth and ribonucleic acid synthesis in human mammary carcinoma.
    Biochemical pharmacology, 1981, Aug-01, Volume: 30, Issue:15

    Topics: Antineoplastic Agents; Aspartic Acid; Breast Neoplasms; Cell Division; Cell Line; Drug Synergism; Female; Fluorouracil; Humans; Organophosphorus Compounds; Phosphonoacetic Acid; Poly A; RNA, Neoplasm; Uridine Triphosphate

1981
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
    Magnetic resonance in medicine, 1994, Volume: 32, Issue:5

    Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatine; Gadolinium; Gadolinium DTPA; Glycolysis; Humans; Hydrogen; Image Enhancement; Ischemia; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Necrosis; Organometallic Compounds; Pentetic Acid; Pilot Projects

1994
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.
    Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3

    Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colonic Neoplasms; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Female; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lung Neoplasms; Male; Melanoma; Mitochondria; Orotic Acid; Ovarian Neoplasms; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Prostatic Neoplasms; Ribonucleotides; Sodium Bicarbonate; Software; Tumor Cells, Cultured

1996
Drug-resistant breast cancer cells frequently retain expression of a functional wild-type p53 protein.
    Carcinogenesis, 1996, Volume: 17, Issue:7

    Topics: Amides; Antineoplastic Agents; Aspartic Acid; Blotting, Western; Breast Neoplasms; Cell Cycle; Clone Cells; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Flow Cytometry; Gene Expression; Genes, p53; Humans; Immunohistochemistry; Melphalan; Mitoxantrone; Neoplasm Proteins; Nuclear Proteins; Phosphonoacetic Acid; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Pyrazoles; Ribonucleosides; Ribose; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1996
White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain; Brain Diseases; Breast Neoplasms; Carmustine; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Creatine; Cyclophosphamide; Demyelinating Diseases; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Neoplasm Staging; Prospective Studies

1998
The key to the antiestrogenic mechanism of raloxifene is amino acid 351 (aspartate) in the estrogen receptor.
    Cancer research, 1998, May-01, Volume: 58, Issue:9

    Topics: Aspartic Acid; Blotting, Northern; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Humans; Mutagenesis, Site-Directed; Piperidines; Point Mutation; Raloxifene Hydrochloride; Receptors, Estrogen; RNA, Messenger; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured

1998
Non-radioactive detection of K-ras mutations by nested allele specific PCR and oligonucleotide hybridization.
    Molecular and cellular probes, 1998, Volume: 12, Issue:5

    Topics: Alanine; Amino Acid Substitution; Animals; Aspartic Acid; Breast Neoplasms; Codon; Colonic Neoplasms; DNA Mutational Analysis; DNA Primers; Female; Genes, ras; Glycine; Heterozygote; Humans; Lung Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Probes; Point Mutation; Polymerase Chain Reaction; Transplantation, Heterologous; Tumor Cells, Cultured

1998
Aminopeptidase activities in breast cancer tissue.
    Clinical chemistry, 1999, Volume: 45, Issue:10

    Topics: Aminopeptidases; Aspartic Acid; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Membrane; Female; Fluorometry; Glutamine; Glutamyl Aminopeptidase; Humans; Middle Aged; Solubility

1999
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
    Oncogene, 2001, Jan-04, Volume: 20, Issue:1

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan

2001
Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:3

    Topics: Animals; Aspartic Acid; Breast Neoplasms; Cell Survival; Cisplatin; Colonic Neoplasms; Drug Carriers; Female; Humans; Kidney; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Micelles; Polyethylene Glycols; Stomach Neoplasms; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured

2001
5-Iododeoxyuridine increases the efficacy of the radioimmunotherapy of human tumors growing in nude mice.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1992, Volume: 33, Issue:8

    Topics: Animals; Aspartic Acid; Breast Neoplasms; Deoxycytidine; Drug Therapy, Combination; Humans; Idoxuridine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Radioimmunotherapy; Tetrahydrouridine; Transplantation, Heterologous

1992
Biochemical modulation: a modality that has come of therapeutic age.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:10

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Breast Neoplasms; Female; Fluorouracil; Humans; Leucovorin; Mitoxantrone; Phosphonoacetic Acid

1991
Uracil nucleotide synthesis in a human breast cancer cell line (MCF-7) and in two drug-resistant sublines that contain increased levels of enzymes of the de novo pyrimidine pathway.
    Molecular pharmacology, 1986, Volume: 30, Issue:2

    Topics: Amides; Aspartate Carbamoyltransferase; Aspartic Acid; Breast Neoplasms; Carbamoyl-Phosphate Synthase (Ammonia); Cell Line; Dihydroorotase; Drug Resistance; Female; Humans; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Uracil Nucleotides; Uridine

1986
Aspartyl transfer RNA profiles in normal and cancer cells.
    Cancer research, 1972, Volume: 32, Issue:8

    Topics: Animals; Ascites; Aspartic Acid; Breast Neoplasms; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Transformation, Neoplastic; Chromatography; Chromatography, DEAE-Cellulose; Cricetinae; Humans; Liver; Liver Neoplasms; Methods; Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred Strains; RNA, Transfer; Simian virus 40; Tritium

1972
[Urinary excretion of asparagne and aspartate in control subjects and patients with cancer before and after treatment with K-Mg-aspartate].
    Wiener klinische Wochenschrift, 1972, Nov-10, Volume: 84, Issue:45

    Topics: Adolescent; Adult; Aged; Asparagine; Aspartic Acid; Breast Neoplasms; Cholecystitis; Female; Humans; Magnesium; Male; Middle Aged; Neoplasms; Potassium; Stomach Neoplasms

1972
[Potassium-magnesium-aspartate therapy in operated cancer patients].
    Medizinische Klinik, 1971, Oct-22, Volume: 66, Issue:43

    Topics: Adult; Aged; Anemia, Hypochromic; Aspartic Acid; Body Weight; Breast Neoplasms; Female; Hemoglobinometry; Humans; Ketoglutaric Acids; Long-Term Care; Magnesium; Male; Middle Aged; Ovarian Neoplasms; Postoperative Care; Potassium; Rectal Neoplasms; Rehabilitation; Retroperitoneal Neoplasms; Stomach Neoplasms; Thyroid Neoplasms; Tongue Neoplasms

1971
Recalcification of bone metastases by calcium diorotate.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1970, Volume: 11, Issue:6

    Topics: Adult; Aspartic Acid; Biological Transport, Active; Bone and Bones; Bone Neoplasms; Breast Neoplasms; Calcification, Physiologic; Calciphylaxis; Calcium; Decalcification, Pathologic; Female; Humans; Neoplasm Metastasis; Orotic Acid; Phosphoric Acids

1970