aspartic acid has been researched along with Brain Neoplasms in 312 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
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"We performed serial (1)H-MRSI examinations to assess intratumoral metabolite intensities in 16 patients receiving high-dose oral tamoxifen monotherapy for recurrent malignant glioma (WHO grade III or IV) as part of a phase II clinical trial." | 9.13 | Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma. ( Arnold, DL; Assina, R; Caramanos, Z; Langleben, A; Leblanc, R; Preul, MC; Sankar, T; Villemure, JG, 2008) |
"The choline/N-acetyl-aspartate (Cho/NAA) ratio, obtained by the multivoxel spectroscopy with short echo time (TE), was evaluated, in the histological grading of the brain astrocytomas (grades I, II and III-IV) in comparison with the normal cerebral parenchyma." | 9.12 | [Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas]. ( Aragão, Mde F; Araújo, N; Azevedo Filho, HR; Leite, Cda C; Melo, RV; Otaduy, MC; Silva, JL; Valença, MM; Victor, EG, 2007) |
"This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)." | 7.77 | Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011) |
"The purpose of this study was to determine the predictive value of [18F]fluoroethyl-L-tyrosine (FET)-positron emission tomography (PET) and magnetic resonance (MR) spectroscopy for tumor diagnosis in patients with suspected gliomas." | 7.73 | Multimodal metabolic imaging of cerebral gliomas: positron emission tomography with [18F]fluoroethyl-L-tyrosine and magnetic resonance spectroscopy. ( Coenen, H; Floeth, FW; Hamacher, K; Langen, KJ; Messing-Jünger, M; Müller, HW; Pauleit, D; Reifenberger, G; Sabel, M; Steiger, HJ; Stummer, W; Weber, F; Wittsack, HJ; Woebker, G; Zilles, K, 2005) |
"To investigate the potential value of pre-external-beam radiation therapy (XRT) choline-to-NAA (N-acetylaspartate) index (CNI), apparent diffusion coefficient (ADC), and relative cerebral blood volume (rCBV) for predicting survival in newly diagnosed patients with glioblastoma multiforme (GBM)." | 7.72 | Survival analysis in patients with glioblastoma multiforme: predictive value of choline-to-N-acetylaspartate index, apparent diffusion coefficient, and relative cerebral blood volume. ( Catalaa, I; Chang, S; Dillon, WP; Henry, RG; Li, X; Lu, Y; Nelson, SJ; Oh, J; Pirzkall, A, 2004) |
" This preclinical study sought to test the efficacy of the food additive Triacetin (glyceryl triacetate, GTA) as a novel therapy to increase acetate bioavailability in glioma cells." | 5.40 | Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. ( Davies, MT; Driscoll, HE; Jaworski, DM; Lawler, SE; Long, PM; Penar, PL; Pendlebury, WW; Spees, JL; Teasdale, BA; Tsen, AR; Viapiano, MS, 2014) |
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 5.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
"Thirteen patients with recurrent glioblastoma were enrolled in RTOG 0625/ACRIN 6677, a prospective multicenter trial in which bevacizumab was used in combination with either temozolomide or irinotecan." | 5.17 | Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677. ( Barboriak, DP; Bokstein, F; Boxerman, JL; Gilbert, MR; McKinstry, RC; Ratai, EM; Safriel, Y; Snyder, BS; Sorensen, AG; Zhang, Z, 2013) |
"We performed serial (1)H-MRSI examinations to assess intratumoral metabolite intensities in 16 patients receiving high-dose oral tamoxifen monotherapy for recurrent malignant glioma (WHO grade III or IV) as part of a phase II clinical trial." | 5.13 | Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma. ( Arnold, DL; Assina, R; Caramanos, Z; Langleben, A; Leblanc, R; Preul, MC; Sankar, T; Villemure, JG, 2008) |
"The choline/N-acetyl-aspartate (Cho/NAA) ratio, obtained by the multivoxel spectroscopy with short echo time (TE), was evaluated, in the histological grading of the brain astrocytomas (grades I, II and III-IV) in comparison with the normal cerebral parenchyma." | 5.12 | [Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas]. ( Aragão, Mde F; Araújo, N; Azevedo Filho, HR; Leite, Cda C; Melo, RV; Otaduy, MC; Silva, JL; Valença, MM; Victor, EG, 2007) |
" There are a number of metabolites that can be identified by standard brain proton MRS but only a few of them has a clinical significance in diagnosis of gliomas including N-acetylaspartate, choline, creatine, myo-inositol, lactate, and lipids." | 4.89 | Potential of MR spectroscopy for assessment of glioma grading. ( Bulik, M; Jancalek, R; Mechl, M; Skoch, A; Vanicek, J, 2013) |
" This biochemical information can be processed and presented as density maps of several metabolites, among them N-acetylaspartate (marker of neuronal viability), choline (marker of membrane turnover), creatine (related to the energy state of the cells), myo-Inositol (exclusively found in astrocytes), lipids and lactate (observed in necrosis and other pathological processes) which mean relevant information in the context of brain tumors." | 4.85 | Proton magnetic resonance spectroscopy imaging in the study of human brain cancer. ( Celda, B; Martínez-Bisbal, MC, 2009) |
" These methods were evaluated for segmentation of volumetric MRSI studies of gliomas using maps of the choline to N-acetylaspartate ratio, and a qualitative comparison of lesion volumes carried out." | 3.91 | Lesion segmentation for MR spectroscopic imaging using the convolution difference method. ( Maudsley, AA, 2019) |
"Purpose To determine whether regions of low apparent diffusion coefficient (ADC) with high relative cerebral blood volume (rCBV) represented elevated choline (Cho)-to-N-acetylaspartate (NAA) ratio (hereafter, Cho/NAA ratio) and whether their volumes correlated with progression-free survival (PFS) and overall survival (OS) in patients with glioblastoma (GBM)." | 3.85 | Multiparametric MR Imaging of Diffusion and Perfusion in Contrast-enhancing and Nonenhancing Components in Patients with Glioblastoma. ( Boonzaier, NR; Larkin, TJ; Matys, T; Price, SJ; van der Hoorn, A; Yan, JL, 2017) |
"Eighteen patients with newly diagnosed, histologically confirmed glioblastoma had 3D-MR proton spectroscopic imaging (MRSI) along with T2 and T1 gadolinium-enhanced MR images at simulation and at boost treatment planning after 17 to 20 fractions of radiation therapy." | 3.80 | 3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy. ( Anderson, CM; Bayouth, JE; Buatti, JM; Capizzano, AA; Clerkin, PP; Magnotta, V; McGuire, SM; Morris, A; Muruganandham, M; Smith, BJ; Smith, MC, 2014) |
"Peritumoral N-acetylaspartate (NAA)/creatine (Cr), choline (Cho)/Cr, Cho/NAA and rCBV significantly differentiated glioblastomas from intracranial metastases." | 3.78 | Differentiation of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy, diffusion and perfusion metrics at 3 T. ( Fezoulidis, I; Fountas, K; Kapsalaki, E; Kousi, E; Svolos, P; Theodorou, K; Tsougos, I, 2012) |
"There is significant elevation of the choline (Cho) /creatine (Cr) ratio, Cho peak and depression of the N-acetylaspartate (NAA) peak in gliomas." | 3.78 | Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas. ( Shang, HB; Zhang, WF; Zhao, WG, 2012) |
"This study was designed to evaluate proton magnetic resonance spectroscopy ((1)H-MRS) for monitoring the WHO grade II glioma (low-grade glioma (LGG)) treated with temozolomide (TMZ)." | 3.77 | Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy. ( Abud, L; Capelle, L; Chiras, J; Costalat, R; De Marco, G; Guillevin, R; Habas, C; Hoang-Xuan, K; Menuel, C; Taillibert, S; Vallée, JN, 2011) |
" The aim of this work is to evaluate whether regional cerebral blood volume (rCBV), as well as choline (Cho), N-acetyl-aspartate (NAA) and myo-inositol (mIns) concentrations differ between tumefactive lesions and World Health Organization (WHO) grade II-III gliomas." | 3.77 | Metabolism and regional cerebral blood volume in autoimmune inflammatory demyelinating lesions mimicking malignant gliomas. ( Blasel, S; Hattingen, E; Jansen, V; Mueller, K; Pfeilschifter, W; Zanella, F, 2011) |
"Metabolite maps of N-acetyl aspartate, choline and creatine were generated using (1)H-CSI data from the brain of healthy volunteers and patients with tumor and epilepsy." | 3.76 | Grid-free interactive and automated data processing for MR chemical shift imaging data. ( Confort-Gouny, S; Cozzone, PJ; Guye, M; Kober, F; Le Fur, Y; Nicoli, F, 2010) |
"The purpose of this study was to determine the predictive value of [18F]fluoroethyl-L-tyrosine (FET)-positron emission tomography (PET) and magnetic resonance (MR) spectroscopy for tumor diagnosis in patients with suspected gliomas." | 3.73 | Multimodal metabolic imaging of cerebral gliomas: positron emission tomography with [18F]fluoroethyl-L-tyrosine and magnetic resonance spectroscopy. ( Coenen, H; Floeth, FW; Hamacher, K; Langen, KJ; Messing-Jünger, M; Müller, HW; Pauleit, D; Reifenberger, G; Sabel, M; Steiger, HJ; Stummer, W; Weber, F; Wittsack, HJ; Woebker, G; Zilles, K, 2005) |
"Diffusion tensor imaging (DTI) and MR spectroscopy are noninvasive, quantitative tools for the preoperative assessment of gliomas with which the quantitative parameter fractional anisotropy (FA) and the concentration of neurometabolites N-acetylaspartate (NAA), choline (Cho), creatine (Cr) of the brain can be determined." | 3.73 | Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study. ( Ding, XQ; Fiehler, J; Goebell, E; Hagel, C; Heese, O; Kucinski, T; Nietz, S; Paustenbach, S; Westphal, M; Zeumer, H, 2006) |
"The ratios of choline (Cho) to N-acetylaspartate (NAA) and Cho to creatine (Cr) in those with high-grade astrocytomas (n=4) were significantly higher than in those with low-grade astrocytomas (n=17) (t=2." | 3.73 | In vivo research in astrocytoma cell proliferation with 1H-magnetic resonance spectroscopy: correlation with histopathology and immunohistochemistry. ( Chen, J; Chen, XL; Huang, SL; Li, T, 2006) |
"In vivo magnetic resonance spectroscopy (MRS) studies of glial brain tumours reported that higher grade of astrocytoma is associated with increased level of choline-containing compounds (Cho) and decreased levels of N-acetylaspartate (NAA) and creatine and phosphocreatine (Cr)." | 3.73 | In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy. ( Belan, V; Béres, A; De Riggo, J; Dobrota, D; Galanda, M; Likavcanová, K; Liptaj, T; Mlynárik, V; Prónayová, N, 2005) |
"To evaluate an intracranial polymer implant containing bromodeoxyuridine (BrdUrd) and N-(phosphonacetyl)-L-aspartic acid (PALA) in combination with external beam radiotherapy (EBRT) in the treatment of a rat glioma." | 3.72 | Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy. ( Lehnert, S; Li, Y; Owusu, A, 2004) |
"To investigate the potential value of pre-external-beam radiation therapy (XRT) choline-to-NAA (N-acetylaspartate) index (CNI), apparent diffusion coefficient (ADC), and relative cerebral blood volume (rCBV) for predicting survival in newly diagnosed patients with glioblastoma multiforme (GBM)." | 3.72 | Survival analysis in patients with glioblastoma multiforme: predictive value of choline-to-N-acetylaspartate index, apparent diffusion coefficient, and relative cerebral blood volume. ( Catalaa, I; Chang, S; Dillon, WP; Henry, RG; Li, X; Lu, Y; Nelson, SJ; Oh, J; Pirzkall, A, 2004) |
" The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
" The concentration of taurine (Tau) in medulloblastomas was 29." | 3.72 | In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004) |
"Data obtained preoperatively from three-dimensional (3D)/proton magnetic resonance (MR) spectroscopy were compared with the results of histopathological assays of tissue biopsies obtained during surgery to verify the sensitivity and specificity of a choline-containing compound-N-acetylaspartate index (CNI) used to distinguish tumor from nontumorous tissue within T2-hyperintense and contrast-enhancing lesions of patients with untreated gliomas." | 3.71 | Histopathological validation of a three-dimensional magnetic resonance spectroscopy index as a predictor of tumor presence. ( Berger, MS; Dillon, WP; Graves, EE; Lu, Y; McDermott, MW; McKnight, TR; Nelson, SJ; Pirzkall, A; Vigneron, DB; von dem Bussche, MH, 2002) |
" MRS of normal brain parenchyma displays 4 main metabolites: N-acetyl aspartate (neuronal marker), creatine (cellular density marker), choline (membrane activity marker) and myoinositol (glial marker); pathological processes lead to variations of the level of these metabolites and/or the appearance of abnormal metabolites (lactate), following different patterns according to pathological process involved: glioma, meningioma, metastasis, bacterial or toxoplasmic abscess, radionecrosis." | 3.71 | [Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors]. ( Confort-Gouny, S; Cozzone, PJ; Dufour, H; Galanaud, D; Le Fur, Y; Nicoli, F; Peragut, JC; Ranjeva, JP; Roche, P; Viout, P, 2002) |
" Non-neoplastic lesions such as cerebral infarctions and brain abscesses are marked by decreases in choline (Cho), creatine (Cr) and N-acetyl-aspartate (NAA), while tumours generally have elevated Cho and decreased levels of Cr and NAA." | 3.71 | Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions. ( Herminghaus, S; Krings, T; Lanfermann, H; Marquardt, G; Möller-Hartmann, W; Pilatus, U; Zanella, FE, 2002) |
"Seven patients responded to tamoxifen therapy (three with glioblastomas multiforme; four with anaplastic astrocytomas), and nine did not (six with glioblastomas multiforme; three with anaplastic astrocytomas)." | 3.70 | Using proton magnetic resonance spectroscopic imaging to predict in vivo the response of recurrent malignant gliomas to tamoxifen chemotherapy. ( Arnold, DL; Caramanos, Z; Langleben, A; LeBlanc, R; Preul, MC; Shenouda, G; Villemure, JG, 2000) |
" We compared the LR sensitivity, specificity, and receiver operator characteristic (ROC) curve area (Az) with the sensitivity and specificity of blinded and unblinded qualitative MRS interpretations and a choline (Cho)/N-acetylaspartate (NAA) amplitude ratio criterion." | 3.70 | Discrimination between neoplastic and nonneoplastic brain lesions by use of proton MR spectroscopy: the limits of accuracy with a logistic regression model. ( Bowen, W; Butzen, J; Chetty, V; Donahue, K; Haughton, V; Kim, T; Krouwer, H; Li, SJ; Mark, L; Meyer, G; Mueller, W; Neppl, R; Prost, R; Rand, S, 2000) |
"(a) Hamartomas showed higher N-acetyl aspartate/creatine, creatine/choline, and N-acetyl aspartate/choline ratios than gliomas." | 3.69 | Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation. ( Castillo, M; Green, C; Greenwood, R; Kwock, L; Schiro, S; Smith, K; Wilson, D, 1995) |
" All high-grade gliomas (n = 37) showed high choline and low or absent N-acetyl-L-aspartate and creatine along with lipid and/or lactate, whereas low-grade gliomas (n = 23) were characterized by low N-acetyl-aspartate and creatine and high choline and presence of only lactate." | 3.69 | Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. ( Chhabra, DK; Gupta, RK; Jain, VK; Pandey, R; Poptani, H; Roy, R, 1995) |
" The NAA (N-acetylaspartate)/Cho (choline) ratio of Grade 2 astrocytoma was higher than that of Grade 4." | 3.69 | Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy. ( Bandou, K; Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1995) |
" We used proton nuclear magnetic resonance spectroscopy to detect the presence of simple metabolites (such as lactic acid, creatine/phosphocreatine, N-acetyl aspartate, and the "choline" pool) in extracts of a human glioma grown subcutaneously in athymic ("nu/nu") mice." | 3.69 | Effects of therapy on the 1H NMR spectrum of a human glioma line. ( Cazzaniga, S; Charles, HC; Schold, SC; Sostman, HD, 1994) |
"Postradiation treatment necrosis is one of the most serious late sequelae and appears within 6 months." | 3.01 | Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis. ( Aseel, A; McCarthy, P; Mohammed, A, 2023) |
"Linear regression analyses between seizure duration and NAA/Cr decrease was not significant." | 2.69 | Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy. ( Andermann, F; Arnold, DL; Cendes, F; Dubeau, F; Li, LM; Miller, SP; Tasch, E, 2000) |
"necrosis in patients with primary brain tumors or brain metastasis." | 2.53 | Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis. ( Chen, YC; Chuang, MT; Liu, YS; Tsai, YS; Wang, CK, 2016) |
"The choline/NAA ratio was 3." | 2.40 | Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas. ( Ball, WS; Ballard, E; Dunn, RS; Egnaczyk, GF; Holland, SK; Hwang, JH, 1998) |
"Seizures are common in patients with gliomas; however, the mechanisms of epileptogenesis in gliomas have not been fully understood." | 1.62 | Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas. ( Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S, 2021) |
"Introduction: Brain tumors if timely diagnosed are sure to be treated through shorter processes." | 1.48 | The Role of Single Voxel MR Spectroscopy, T2 Relaxation Time and Apparent Diffusion Coefficient in Determining the Cellularity of Brain Tumors by MATLAB Software ( Abdolmohammadi, J; Amiri, J; Arefan, D; Faeghi, F; Haghighatkhah, H; Zali, A, 2018) |
"Thirty-five patients with brain metastases underwent baseline single slice multi-voxel MR spectroscopy (MRS) examination for measurement of hippocampal h-tNAA together with baseline battery of neurocognitive tests focused on memory (Auditory Verbal Learning Test and Brief Visuospatial Memory Test - Revised) as well as quality of life questionnaires (EORTC QLQ-C30 a EORTC QLQ-BN20)." | 1.46 | Post-WBRT cognitive impairment and hippocampal neuronal depletion measured by in vivo metabolic MR spectroscopy: Results of prospective investigational study. ( Bulik, M; Burkon, P; Dobiaskova, M; Hynkova, L; Jancalek, R; Kazda, T; Laack, NN; Pospisil, P; Slampa, P, 2017) |
"Glioma is the most common type of the primary CNS tumor." | 1.43 | Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro. ( Cui, Y; Li, FY; Li, HX; Shi, WQ; Wang, JZ; Xu, YJ; Zeng, QS, 2016) |
"Thirty-nine patients after the standard treatment of a glioblastoma underwent advanced imaging by MRS and ADC at the time of suspected recurrence - median time to progression was 6." | 1.43 | Advanced MRI increases the diagnostic accuracy of recurrent glioblastoma: Single institution thresholds and validation of MR spectroscopy and diffusion weighted MR imaging. ( Bulik, M; Jancalek, R; Kazda, T; Lakomy, R; Pospisil, P; Slampa, P; Smrcka, M, 2016) |
"Patients with brain metastases underwent whole brain radiotherapy (WBRT) to a dose of 30 Gy in ten fractions daily." | 1.42 | Hippocampal proton MR spectroscopy as a novel approach in the assessment of radiation injury and the correlation to neurocognitive function impairment: initial experiences. ( Bulik, M; Burkon, P; Dobiaskova, M; Hynkova, L; Jancalek, R; Kazda, T; Pospisil, P; Slampa, P, 2015) |
"Neurocytomas are tumors or neuronal differentiation, typically located within the supratentorial ventricular system." | 1.40 | Primary central neurocytoma of the mesencephalic tectum in a pediatric patient. ( Gordillo, C; Jimenez, JA; Manzanares, R; Navas, M; Shakur, SF; Sola, RG; Torres, CV, 2014) |
" This preclinical study sought to test the efficacy of the food additive Triacetin (glyceryl triacetate, GTA) as a novel therapy to increase acetate bioavailability in glioma cells." | 1.40 | Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma. ( Davies, MT; Driscoll, HE; Jaworski, DM; Lawler, SE; Long, PM; Penar, PL; Pendlebury, WW; Spees, JL; Teasdale, BA; Tsen, AR; Viapiano, MS, 2014) |
"Fifty-nine solitary brain metastases were evaluated with conventional and nonmorphological MR imaging: DWI, PWI and MR spectroscopy." | 1.38 | Magnetic resonance imaging of solitary brain metastases: main findings of nonmorphological sequences. ( Colosimo, C; De Waure, C; Di Lella, GM; Gaudino, S; Gualano, MR; Lo Russo, VS; Piludu, F; Quaglio, FR; Russo, R, 2012) |
"The histological diagnosis was anaplastic oligodendroglioma (WHO grade III)." | 1.37 | [Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma]. ( Akutsu, H; Anno, I; Isobe, T; Masumoto, T; Matsumura, A; Nakai, K; Shiigai, M; Takano, S; Yamamoto, T, 2011) |
"Segmental neurofibromatosis 1 (segmental NF-1) is a rare genodermatosis caused by somatic mutations in the NF-1 gene." | 1.36 | A clinical and magnetic resonance spectroscopy study of a brain tumor in a patient with segmental neurofibromatosis. ( Ben Yahia, S; Boughammoura-Bouatay, A; Chebel, S; Frih-Ayed, M; Golli, M; Khairallah, M; Salem, R, 2010) |
"We report 12 cases of Gliomatosis cerebri (GC), a rare brain neoplasm, to define its semeiologic criteria." | 1.36 | Gliomatosis cerebri, imaging findings of 12 cases. ( Cosnard, G; de Coene, B; Desclée, P; Godfraind, C; Hernalsteen, D; Rommel, D, 2010) |
"Gliosarcoma is an uncommon variant of glioblastoma multiforme, which is composed of gliomatous and sarcomatous elements." | 1.35 | Giant infantile gliosarcoma: magnetic resonance imaging findings. ( Bulakbasi, N; Chen, L; Kocaoglu, M; Onguru, O; Sanal, HT, 2008) |
"Eleven patients with primary brain tumors undergoing cranial radiation therapy (RT) were included." | 1.35 | Metabolic alterations: a biomarker for radiation-induced normal brain injury-an MR spectroscopy study. ( Cao, Y; Chenevert, TL; Elias, A; Gomez Hassan, DM; Junck, L; Lawrence, TS; McKeever, P; Nagesh, V; Rogers, L; Sundgren, PC; Tsien, C, 2009) |
"Desmoplastic infantile gangliogliomas (DIG) are rare benign intracranial neoplasms of early childhood with involvement of superficial cerebral cortex and leptomeninges." | 1.35 | Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint. ( Balaji, R; Ramachandran, K, 2009) |
"Using discriminant analysis, this study found that MR spectroscopy in combination with ADC ratio, rather than ADC value, can improve the ability to differentiate recurrent glioma and radiation injury." | 1.34 | Distinction between recurrent glioma and radiation injury using magnetic resonance spectroscopy in combination with diffusion-weighted imaging. ( Feng, DC; Li, CF; Liu, H; Zeng, QS; Zhen, JH, 2007) |
"Gliomatosis cerebri is a rare brain tumor with a short survival time; for this reason, it is difficult to establish the degree of aggressivity in vivo." | 1.34 | 1H MR spectroscopy in the assessment of gliomatosis cerebri. ( Benito, C; Desco, M; García-Barreno, P; Guzmán-de-Villoria, JA; Muñoz, L; Reig, S; Sánchez-González, J, 2007) |
"We present a gliomatosis cerebri case in which we made the radiological diagnosis using the MR spectroscopy findings; the diagnosis was confirmed by subsequent biopsy and histopathologic evaluation." | 1.33 | Multivoxel magnetic resonance spectroscopy in gliomatosis cerebri. ( Basak, M; Can, M; Erturk, M; Karatag, O; Tanik, C; Uysal, E; Yildirim, H, 2005) |
"Six patients with brain metastases, 13 healthy volunteers, and a phantom containing brain metabolites were examined using two clinical MR instruments operating at 1." | 1.33 | Clinical 1H magnetic resonance spectroscopy of brain metastases at 1.5T and 3T. ( Gribbestad, IS; Kristoffersen, A; Lundgren, S; Singstad, T; Sjøbakk, TE; Sonnewald, U; Svarliaunet, AJ, 2006) |
"One hundred and four metastatic brain tumors were evaluated by long-echo (TR, 2000 ms; TE, 136 ms) single-voxel volume-selected proton MRS." | 1.33 | Proton magnetic resonance spectroscopy (MRS) of metastatic brain tumors: variations of metabolic profile. ( Chernov, MF; Hayashi, M; Hori, T; Izawa, M; Ono, Y, 2006) |
"Ten patients with untreated gliomas were examined on a 1." | 1.32 | Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas. ( Buslei, R; Fahlbusch, R; Ganslandt, O; Gruber, S; Moser, E; Nimsky, C; Stadlbauer, A, 2004) |
"Combined treatment of primary brain tumors (surgery + postoperative radiotherapy) causes alteration of brain metabolism, even in regions of the brain far from the postoperative tumor bed and receiving relatively low total doses of radiation." | 1.32 | 1H-MR spectroscopy of normal brain tissue before and after postoperative radiotherapy because of primary brain tumors. ( Maciejewski, B; Rutkowski, T; Sokol, M; Tarnawski, R, 2003) |
"The diagnosis and therapy of childhood brain tumors, most of which are low grade, can be complicated because of their frequent adjacent location to crucial structures, which limits diagnostic biopsy." | 1.32 | Noninvasive magnetic resonance spectroscopic imaging biomarkers to predict the clinical grade of pediatric brain tumors. ( Anthony, DC; Astrakas, LG; Black, PM; De Girolami, U; Tarbell, NJ; Tzika, AA; Zarifi, MK; Zurakowski, D, 2004) |
"Eighty-five brain metastases in 81 patients were investigated before treatment and 16-18h thereafter." | 1.32 | Early metabolic changes in metastatic brain tumors after Gamma Knife radiosurgery: 1H-MRS study. ( Abe, K; Chernov, MF; Hayashi, M; Hori, T; Izawa, M; Kubo, O; Ono, Y; Usukura, M, 2004) |
"The differential diagnosis between brain abscesses and necrotic tumors such as glioblastomas is sometimes difficult to establish by conventional computed tomography and magnetic resonance imaging." | 1.31 | Brain abscess and glioblastoma identified by combined proton magnetic resonance spectroscopy and diffusion-weighted magnetic resonance imaging--two case reports. ( Harada, M; Kageji, T; Nagahiro, S; Nakaiso, M; Takimoto, O; Uno, M, 2002) |
"Choline peak area was increased in tumor, creatine and N-acetyl aspartate were decreased in edema and tumor compared with unaffected brain tissue." | 1.31 | 1H chemical shift imaging characterization of human brain tumor and edema. ( Oudkerk, M; Sijens, PE, 2002) |
"High-grade brain tumors are known to have a high rate of glucose (Glc) consumption." | 1.31 | High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging. ( Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A, 2001) |
"The diagnosis of gliomatosis cerebri with MR imaging is known to be difficult." | 1.31 | MR spectroscopy in gliomatosis cerebri. ( Bendszus, M; Burger, R; Klein, R; Schichor, C; Solymosi, L; Tonn, JC; Warmuth-Metz, M, 2000) |
"Most of the brain tumors were characterized by strongly reduced total N-acetylaspartyl compounds and marked increases of myo-inositol and choline-containing compounds, consistent with a lack of neuroaxonal tissue and a proliferation of glial cells." | 1.31 | Quantitative proton magnetic resonance spectroscopy of focal brain lesions. ( Dechent, P; Frahm, J; Hanefeld, F; Herms, J; Markakis, E; Maxton, C; Wilken, B, 2000) |
"We examined 120 patients with brain tumors using a 1." | 1.31 | In vivo proton magnetic resonance spectroscopy of brain tumors. ( Fountas, KN; Gotsis, SD; Johnston, KW; Kapsalaki, EZ; Kapsalakis, JZ; Papadakis, N; Robinson, JS; Smisson , HF, 2000) |
"The diagnosis of brain tumors after high-dose radiation therapy is frequently limited by the lack of metabolic discrimination available with conventional imaging methods." | 1.31 | Serial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery. ( Chang, S; Dillon, WP; Graves, EE; Larson, D; McDermott, M; Nelson, SJ; Prados, MD; Verhey, L; Vigneron, DB, 2001) |
"First, it allows to distinguish brain tumors from abscesses." | 1.31 | [Brain tumors: interest of magnetic resonance spectroscopy for the diagnosis and the prognosis]. ( Berry, I; Ibarrola, D; Malet-Martino, M; Sabatier, J, 2001) |
"Children who have brain tumors are at risk for a variety of treatment-related sequelae, including neuropsychological and cognitive impairment, neurologic deficits, and neuroendocrinologic disturbances." | 1.30 | Treatment of brain tumors in children is associated with abnormal MR spectroscopic ratios in brain tissue remote from the tumor site. ( Davis, PC; Morris, R; Padgett, CA; Shapiro, MB; Waldrop, SM, 1998) |
"Seventeen brain tumors were measured by 1H-CSI (chemical shift imaging) in a 1." | 1.30 | Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method. ( Furuya, S; Ide, M; Kizu, O; Maeda, T; Morishita, H; Naruse, S; Ueda, S, 1997) |
"Fifteen patients with brain tumors and 10 healthy children underwent MR imaging and MR spectroscopy on a 1." | 1.30 | Multivoxel proton MR spectroscopy and hemodynamic MR imaging of childhood brain tumors: preliminary observations. ( Barnes, PD; Tzika, AA; Vajapeyam, S, 1997) |
"Choline signals were increased in tumour margins of high grade gliomas and more diffusely in low grade gliomas." | 1.29 | Localized proton spectroscopy of inoperable brain gliomas. Response to radiation therapy. ( Go, KG; Heesters, MA; Kamman, RL; Mooyaart, EL, 1993) |
"We encountered a case of brain abscess that was difficult to differentiate from glioblastoma." | 1.29 | Brain abscess observed by localized proton magnetic resonance spectroscopy. ( Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1994) |
"Higher grades of brain tumors in this study were associated with higher Cho/reference and lower NAA/reference values." | 1.29 | Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy. ( Arai, N; Fujiwara, S; Hara, K; Kayama, T; Kumabe, T; Ono, Y; Sato, K; Shimizu, H; Tominaga, T; Yoshimoto, T, 1996) |
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 1.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
"Thirteen cases of brain cancer treated by radiation therapy were examined by 1H magnetic resonance spectroscopy and gadolinium-enhanced T1-weighted magnetic resonance imaging and reexamined at 2-month intervals." | 1.29 | Hydrogen magnetic resonance spectroscopy follow-up after radiation therapy of human brain cancer. Unexpected inverse correlation between the changes in tumor choline level and post-gadolinium magnetic resonance imaging contrast. ( Levendag, PC; Oudkerk, M; Sijens, PE; van Dijk, P; Vecht, CJ, 1995) |
"Seventy patients with intracranial neoplasms were studied before receiving surgery, radiotherapy or chemotherapy." | 1.29 | Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives. ( Calabrese, G; Falini, A; Lipari, S; Losa, M; Origgi, D; Scotti, G; Triulzi, F, 1996) |
"Total creatine was decreased in all brain tumors in comparison with normal brain tissues, but was relatively higher in neuroectodermal tumors than in other brain tumors." | 1.29 | Proton magnetic resonance spectroscopy of brain tumors: an in vitro study. ( Kajiwara, H; Kinoshita, Y; Koga, Y; Yokota, A, 1994) |
"Meningiomas were further characterized by the presence of alanine." | 1.29 | Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours. ( Blackband, SJ; Horsman, A; Lowry, M; Manton, DJ, 1995) |
"External radiation therapy for brain tumors exposes healthy areas of brain to considerable doses of radiation." | 1.29 | Radiation-induced changes in human brain metabolites as studied by 1H nuclear magnetic resonance spectroscopy in vivo. ( Johansson, R; Kauppinen, R; Soimakallio, S; Tenhunen, M; Usenius, JP; Usenius, T; Vainio, P, 1995) |
"Choline values were lower in chronic radiation necrosis than in solid anaplastic tumors (P < ." | 1.28 | Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevance. ( Alger, JR; Bizzi, A; Di Chiro, G; Dietz, MJ; Dwyer, AJ; Frank, JA; Fulham, MJ; Raman, R; Shih, HH; Sobering, GS, 1992) |
"This report examines the safety issues related to the nutritive sweetener aspartame, including possible toxic effects of aspartame's component amino acids, aspartic acid and phenylalanine, and its major decomposition products, methanol and diketopiperazine, and the potential synergistic effect of aspartame and dietary carbohydrate on brain neurochemicals." | 1.27 | Aspartame. Review of safety issues. Council on Scientific Affairs. ( , 1985) |
"In 58 patients with brain tumors of a different histological structure the authors examined the amino acid content in the CSF (in 30 cases ventricular and in 28--lumbar fluid)." | 1.26 | [Amino acid composition of ventricular and lumbar cerebrospinal fluid in brain tumors]. ( Krivopusk, ME, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (3.53) | 18.7374 |
1990's | 68 (21.79) | 18.2507 |
2000's | 116 (37.18) | 29.6817 |
2010's | 103 (33.01) | 24.3611 |
2020's | 14 (4.49) | 2.80 |
Authors | Studies |
---|---|
Rudnay, M | 1 |
Waczulikova, I | 1 |
Bullova, A | 1 |
Rjaskova, G | 1 |
Chorvath, M | 1 |
Jezberova, M | 1 |
Lehotska, V | 1 |
Mekala, JR | 1 |
Kurappalli, RK | 1 |
Ramalingam, P | 1 |
Moparthi, NR | 1 |
Farche, MK | 1 |
Fachinetti, NO | 1 |
da Silva, LR | 1 |
Matos, LA | 1 |
Appenzeller, S | 1 |
Cendes, F | 2 |
Reis, F | 1 |
Tran, D | 3 |
Nguyen, DH | 3 |
Nguyen, HK | 3 |
Nguyen-Thanh, VA | 3 |
Dong-Van, H | 3 |
Nguyen, MD | 3 |
De Stefano, FA | 1 |
Morell, AA | 1 |
Smith, G | 1 |
Warner, T | 1 |
Soldozy, S | 1 |
Elarjani, T | 1 |
Eichberg, DG | 1 |
Luther, E | 1 |
Komotar, RJ | 1 |
Aseel, A | 1 |
McCarthy, P | 1 |
Mohammed, A | 1 |
Tensaouti, F | 1 |
Desmoulin, F | 1 |
Gilhodes, J | 1 |
Roques, M | 1 |
Ken, S | 2 |
Lotterie, JA | 1 |
Noël, G | 1 |
Truc, G | 1 |
Sunyach, MP | 1 |
Charissoux, M | 1 |
Magné, N | 1 |
Lubrano, V | 2 |
Péran, P | 1 |
Cohen-Jonathan Moyal, E | 2 |
Laprie, A | 3 |
Vidya Shankar, R | 1 |
Hu, HH | 1 |
Bikkamane Jayadev, N | 1 |
Chang, JC | 1 |
Kodibagkar, VD | 2 |
Zeinali-Rafsanjani, B | 1 |
Mosleh-Shirazi, MA | 1 |
Faghihi, R | 1 |
Saeedi-Moghadam, M | 1 |
Lotfi, M | 1 |
Jalli, R | 1 |
Goryawala, M | 1 |
Saraf-Lavi, E | 1 |
Nagornaya, N | 1 |
Heros, D | 1 |
Komotar, R | 1 |
Maudsley, AA | 5 |
Boban, J | 1 |
Thurnher, MM | 1 |
Brkic, S | 1 |
Lendak, D | 1 |
Bugarski Ignjatovic, V | 1 |
Todorovic, A | 1 |
Kozic, D | 2 |
Wang, AP | 1 |
Suryavanshi, T | 1 |
Marcucci, M | 1 |
Fong, C | 1 |
Whitton, AC | 1 |
Reddy, KKV | 1 |
Flores-Alvarez, E | 1 |
Anselmo Rios Piedra, E | 1 |
Cruz-Priego, GA | 1 |
Durand-Muñoz, C | 1 |
Moreno-Jimenez, S | 2 |
Roldan-Valadez, E | 2 |
Zhao, JP | 1 |
Cui, CX | 1 |
Wang, JC | 1 |
Su, HW | 1 |
Duan, CF | 1 |
Liu, XJ | 1 |
Mishkovsky, M | 1 |
Gusyatiner, O | 1 |
Lanz, B | 2 |
Cudalbu, C | 2 |
Vassallo, I | 2 |
Hamou, MF | 2 |
Bloch, J | 1 |
Comment, A | 1 |
Gruetter, R | 2 |
Hegi, ME | 2 |
Nakae, S | 1 |
Kumon, M | 1 |
Murayama, K | 1 |
Ohba, S | 1 |
Sasaki, H | 1 |
Inamasu, J | 1 |
Kuwahara, K | 1 |
Yamada, S | 1 |
Abe, M | 1 |
Hirose, Y | 1 |
Alirezaei, Z | 1 |
Amouheidari, A | 1 |
Hassanpour, M | 1 |
Davanian, F | 1 |
Iraji, S | 1 |
Shokrani, P | 1 |
Nazem-Zadeh, MR | 1 |
Ditter, P | 1 |
Hattingen, E | 2 |
Gruber, S | 5 |
Heckova, E | 1 |
Strasser, B | 1 |
Považan, M | 1 |
Hangel, GJ | 1 |
Minarikova, L | 1 |
Trattnig, S | 1 |
Bogner, W | 1 |
Liu, Z | 1 |
Zhang, J | 4 |
Qiao, L | 1 |
Sun, T | 1 |
Zheng, X | 1 |
Zheng, M | 1 |
Xie, Z | 1 |
Lai, M | 1 |
Poitry-Yamate, C | 1 |
Gao, W | 1 |
Wang, X | 1 |
Li, F | 2 |
Shi, W | 1 |
Li, H | 1 |
Zeng, Q | 2 |
Carlin, D | 1 |
Babourina-Brooks, B | 1 |
Davies, NP | 1 |
Wilson, M | 1 |
Peet, AC | 2 |
Chen, BB | 1 |
Lu, YS | 1 |
Yu, CW | 1 |
Lin, CH | 1 |
Chen, TW | 1 |
Wei, SY | 1 |
Cheng, AL | 1 |
Shih, TT | 1 |
Pedrosa de Barros, N | 1 |
Meier, R | 1 |
Pletscher, M | 1 |
Stettler, S | 1 |
Knecht, U | 1 |
Herrmann, E | 1 |
Schucht, P | 1 |
Reyes, M | 1 |
Gralla, J | 1 |
Wiest, R | 1 |
Slotboom, J | 1 |
Abdolmohammadi, J | 1 |
Faeghi, F | 1 |
Arefan, D | 1 |
Zali, A | 1 |
Haghighatkhah, H | 1 |
Amiri, J | 1 |
Gurbani, SS | 2 |
Sheriff, S | 1 |
Shim, H | 2 |
Cooper, LAD | 1 |
Choi, C | 4 |
Ganji, S | 1 |
Hulsey, K | 1 |
Madan, A | 2 |
Kovacs, Z | 2 |
Dimitrov, I | 1 |
Zhang, S | 1 |
Pichumani, K | 1 |
Mendelsohn, D | 1 |
Mickey, B | 1 |
Malloy, C | 1 |
Bachoo, R | 1 |
Deberardinis, R | 1 |
Maher, E | 1 |
Ratai, EM | 2 |
Zhang, Z | 1 |
Snyder, BS | 1 |
Boxerman, JL | 1 |
Safriel, Y | 1 |
McKinstry, RC | 1 |
Bokstein, F | 2 |
Gilbert, MR | 1 |
Sorensen, AG | 1 |
Barboriak, DP | 1 |
Lu, SS | 1 |
Kim, SJ | 1 |
Kim, HS | 1 |
Choi, CG | 1 |
Lim, YM | 1 |
Kim, EJ | 1 |
Kim, DY | 1 |
Cho, SH | 1 |
Navas, M | 1 |
Sola, RG | 1 |
Torres, CV | 1 |
Shakur, SF | 1 |
Manzanares, R | 1 |
Gordillo, C | 1 |
Jimenez, JA | 1 |
Balos, DR | 1 |
Gavrilović, S | 1 |
Lavrnić, S | 1 |
Vasić, B | 1 |
Macvanski, M | 1 |
Damjanović, D | 1 |
Opinćal, TS | 1 |
Tsen, AR | 1 |
Long, PM | 1 |
Driscoll, HE | 1 |
Davies, MT | 1 |
Teasdale, BA | 1 |
Penar, PL | 1 |
Pendlebury, WW | 1 |
Spees, JL | 1 |
Lawler, SE | 1 |
Viapiano, MS | 1 |
Jaworski, DM | 1 |
Roder, C | 1 |
Skardelly, M | 1 |
Ramina, KF | 1 |
Beschorner, R | 1 |
Honneger, J | 1 |
Nägele, T | 1 |
Tatagiba, MS | 1 |
Ernemann, U | 1 |
Bisdas, S | 2 |
Mama, N | 1 |
Ben Abdallah, A | 1 |
Hasni, I | 1 |
Kadri, K | 1 |
Arifa, N | 1 |
Ladib, M | 1 |
Tlili-Graiess, K | 1 |
Muruganandham, M | 1 |
Clerkin, PP | 1 |
Smith, BJ | 1 |
Anderson, CM | 1 |
Morris, A | 1 |
Capizzano, AA | 1 |
Magnotta, V | 1 |
McGuire, SM | 1 |
Smith, MC | 1 |
Bayouth, JE | 1 |
Buatti, JM | 1 |
Raschke, F | 1 |
Jones, TL | 1 |
Barrick, TR | 1 |
Howe, FA | 3 |
Ganji, SK | 3 |
An, Z | 1 |
Choe, KS | 1 |
Pinho, MC | 1 |
Bachoo, RM | 2 |
Maher, EM | 1 |
Parra, NA | 1 |
Gupta, RK | 2 |
Ishkanian, F | 1 |
Huang, K | 1 |
Walker, GR | 1 |
Padgett, K | 1 |
Roy, B | 1 |
Panoff, J | 1 |
Markoe, A | 1 |
Stoyanova, R | 1 |
Saito, K | 1 |
Toda, M | 1 |
Yoshida, K | 1 |
Deviers, A | 1 |
Filleron, T | 1 |
Rowland, B | 1 |
Laruelo, A | 1 |
Catalaa, I | 3 |
Celsis, P | 1 |
Berry, I | 3 |
Mogicato, G | 1 |
Stadler, KL | 1 |
Ober, CP | 1 |
Feeney, DA | 1 |
Jessen, CR | 1 |
Wataya, T | 1 |
Ishizaki, R | 1 |
Kitagawa, M | 1 |
Tashiro, Y | 1 |
Yamamoto, T | 3 |
Isobe, T | 2 |
Akutsu, H | 2 |
Masumoto, T | 2 |
Ando, H | 1 |
Sato, E | 1 |
Takada, K | 1 |
Anno, I | 2 |
Matsumura, A | 2 |
Bourdillon, P | 1 |
Hlaihel, C | 1 |
Guyotat, J | 1 |
Guillotton, L | 1 |
Honnorat, J | 1 |
Ducray, F | 1 |
Cotton, F | 1 |
Stadlbauer, A | 6 |
Pichler, P | 1 |
Karl, M | 1 |
Brandner, S | 1 |
Lerch, C | 1 |
Renner, B | 1 |
Heinz, G | 1 |
Alam, MS | 1 |
Ahsan, H | 1 |
Sajjad, Z | 1 |
Beg, M | 1 |
Bhatti, U | 1 |
Enam, A | 1 |
Wasay, M | 1 |
Ranjith, G | 1 |
Parvathy, R | 1 |
Vikas, V | 1 |
Chandrasekharan, K | 1 |
Nair, S | 1 |
Wang, J | 1 |
Yin, H | 1 |
Panandikar, A | 1 |
Gandhi, V | 1 |
Sen, S | 1 |
Tang, C | 1 |
Guo, J | 2 |
Chen, H | 2 |
Yao, CJ | 2 |
Zhuang, DX | 2 |
Wang, Y | 2 |
Tang, WJ | 1 |
Ren, G | 2 |
Yao, Y | 1 |
Wu, JS | 2 |
Mao, Y | 1 |
Zhou, LF | 1 |
Ghasemi, K | 1 |
Khanmohammadi, M | 1 |
Saligheh Rad, H | 1 |
Tong, T | 1 |
Yang, Z | 1 |
Chen, JW | 1 |
Zhu, J | 1 |
Yao, Z | 1 |
Lotumolo, A | 2 |
Caivano, R | 2 |
Rabasco, P | 2 |
Iannelli, G | 1 |
Villonio, A | 2 |
D' Antuono, F | 1 |
Gioioso, M | 1 |
Zandolino, A | 2 |
Macarini, L | 2 |
Guglielmi, G | 1 |
Cammarota, A | 2 |
Wang, Q | 1 |
Zhang, H | 1 |
Wu, C | 1 |
Zhu, W | 1 |
Chen, X | 1 |
Xu, B | 1 |
Pospisil, P | 3 |
Kazda, T | 3 |
Bulik, M | 4 |
Dobiaskova, M | 2 |
Burkon, P | 2 |
Hynkova, L | 2 |
Slampa, P | 3 |
Jancalek, R | 4 |
Lin, CP | 1 |
Wang, TL | 1 |
Qin, ZY | 1 |
Chuang, MT | 1 |
Liu, YS | 1 |
Tsai, YS | 1 |
Chen, YC | 1 |
Wang, CK | 1 |
Jarmusch, AK | 1 |
Pirro, V | 1 |
Baird, Z | 1 |
Hattab, EM | 1 |
Cohen-Gadol, AA | 1 |
Cooks, RG | 1 |
Cordova, JS | 1 |
Shu, HK | 1 |
Liang, Z | 1 |
Cooper, LA | 1 |
Holder, CA | 1 |
Olson, JJ | 1 |
Kairdolf, B | 1 |
Schreibmann, E | 1 |
Neill, SG | 1 |
Hadjipanayis, CG | 1 |
Carrera, I | 1 |
Richter, H | 1 |
Beckmann, K | 1 |
Meier, D | 1 |
Dennler, M | 1 |
Kircher, PR | 1 |
Xu, YJ | 1 |
Cui, Y | 1 |
Li, HX | 1 |
Shi, WQ | 1 |
Li, FY | 1 |
Wang, JZ | 1 |
Zeng, QS | 3 |
Lakomy, R | 1 |
Smrcka, M | 1 |
Patriarca, L | 1 |
D'Orazio, F | 1 |
Di Cesare, E | 1 |
Splendiani, A | 1 |
Heiland, DH | 1 |
Mader, I | 2 |
Schlosser, P | 1 |
Pfeifer, D | 1 |
Carro, MS | 1 |
Lange, T | 1 |
Schwarzwald, R | 1 |
Vasilikos, I | 1 |
Urbach, H | 1 |
Weyerbrock, A | 1 |
Yu, W | 1 |
Suliburk, J | 1 |
Eberlin, LS | 1 |
Gilberto González, R | 1 |
Tamrazi, B | 1 |
Nelson, MD | 1 |
Blüml, S | 1 |
Nelson, SJ | 15 |
Li, Y | 3 |
Lupo, JM | 1 |
Olson, M | 1 |
Crane, JC | 1 |
Molinaro, A | 1 |
Roy, R | 2 |
Clarke, J | 1 |
Butowski, N | 1 |
Prados, M | 1 |
Cha, S | 5 |
Chang, SM | 5 |
Rios, C | 1 |
Motola-Kuba, D | 1 |
Matus-Santos, J | 1 |
Villa, AR | 1 |
Laack, NN | 1 |
Artzi, M | 1 |
Liberman, G | 1 |
Vaisman, N | 1 |
Vitinshtein, F | 1 |
Aizenstein, O | 1 |
Ben Bashat, D | 1 |
Boonzaier, NR | 1 |
Larkin, TJ | 1 |
Matys, T | 1 |
van der Hoorn, A | 1 |
Yan, JL | 1 |
Price, SJ | 1 |
Simões, RV | 1 |
Martinez-Aranda, A | 1 |
Martín, B | 1 |
Cerdán, S | 2 |
Sierra, A | 1 |
Arús, C | 2 |
Sankar, T | 1 |
Caramanos, Z | 3 |
Assina, R | 1 |
Villemure, JG | 3 |
Leblanc, R | 3 |
Langleben, A | 2 |
Arnold, DL | 5 |
Preul, MC | 3 |
Srinivasan, R | 1 |
Ratiney, H | 1 |
Lu, Y | 3 |
Su, Y | 1 |
Thakur, SB | 1 |
Karimi, S | 1 |
Du, S | 1 |
Sajda, P | 1 |
Huang, W | 1 |
Parra, LC | 1 |
Guillevin, R | 2 |
Menuel, C | 2 |
Sanson, M | 1 |
Hoang-Xuan, K | 2 |
Chiras, J | 2 |
Crawford, FW | 1 |
Khayal, IS | 1 |
McGue, C | 1 |
Saraswathy, S | 1 |
Pirzkall, A | 5 |
Lamborn, KR | 2 |
Berger, MS | 4 |
Douis, H | 1 |
Jafri, M | 1 |
Sherlala, K | 1 |
Majós, C | 1 |
Aguilera, C | 1 |
Alonso, J | 1 |
Julià-Sapé, M | 1 |
Castañer, S | 1 |
Sánchez, JJ | 1 |
Samitier, A | 1 |
León, A | 1 |
Rovira, A | 1 |
Balaji, R | 1 |
Ramachandran, K | 1 |
Smith, EA | 2 |
Carlos, RC | 2 |
Junck, LR | 1 |
Tsien, CI | 1 |
Elias, A | 2 |
Sundgren, PC | 4 |
Nagesh, V | 1 |
Tsien, C | 1 |
Junck, L | 2 |
Gomez Hassan, DM | 1 |
Lawrence, TS | 1 |
Chenevert, TL | 1 |
Rogers, L | 1 |
McKeever, P | 1 |
Cao, Y | 1 |
Kumar, V | 1 |
Chakrabarti, S | 1 |
Modi, M | 1 |
Sahoo, M | 1 |
Mazzoni, LN | 1 |
Belli, G | 1 |
Ginestroni, A | 1 |
Pratesi, A | 1 |
Agnoloni, S | 1 |
Diciotti, S | 1 |
Mascalchi, M | 1 |
Zierhut, ML | 1 |
Ozturk-Isik, E | 2 |
Chen, AP | 1 |
Park, I | 1 |
Vigneron, DB | 9 |
Blamek, S | 2 |
Larysz, D | 1 |
Ficek, K | 1 |
Sokół, M | 3 |
Miszczyk, L | 1 |
Tarnawski, R | 2 |
Wydmański, J | 2 |
Matulewicz, L | 1 |
Boguszewicz, L | 1 |
Matsusue, E | 1 |
Fink, JR | 1 |
Rockhill, JK | 1 |
Ogawa, T | 1 |
Maravilla, KR | 1 |
Goenka, AH | 1 |
Kumar, A | 1 |
Sharma, R | 1 |
Eslami, R | 1 |
Jacob, M | 1 |
Martínez-Bisbal, MC | 1 |
Celda, B | 1 |
Le Fur, Y | 2 |
Nicoli, F | 2 |
Guye, M | 1 |
Confort-Gouny, S | 2 |
Cozzone, PJ | 2 |
Kober, F | 1 |
Server, A | 3 |
Josefsen, R | 2 |
Kulle, B | 2 |
Maehlen, J | 1 |
Schellhorn, T | 1 |
Gadmar, Ø | 1 |
Kumar, T | 2 |
Haakonsen, M | 1 |
Langberg, CW | 1 |
Nakstad, PH | 2 |
Sijens, PE | 6 |
Desclée, P | 1 |
Rommel, D | 1 |
Hernalsteen, D | 1 |
Godfraind, C | 1 |
de Coene, B | 1 |
Cosnard, G | 1 |
Chebel, S | 1 |
Ben Yahia, S | 1 |
Boughammoura-Bouatay, A | 1 |
Salem, R | 1 |
Golli, M | 1 |
Khairallah, M | 1 |
Frih-Ayed, M | 1 |
Buchfelder, M | 2 |
Doelken, MT | 1 |
Hammen, T | 3 |
Ganslandt, O | 5 |
Girard, N | 1 |
Gadmar, ØB | 1 |
Liu, X | 1 |
Germin, BI | 1 |
Zhong, J | 1 |
Ekholm, S | 1 |
Blasel, S | 1 |
Pfeilschifter, W | 1 |
Jansen, V | 1 |
Mueller, K | 1 |
Zanella, F | 1 |
Weber, MA | 3 |
Henze, M | 2 |
Tüttenberg, J | 1 |
Stieltjes, B | 1 |
Meissner, M | 1 |
Zimmer, F | 1 |
Burkholder, I | 1 |
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Maxton, C | 1 |
Markakis, E | 1 |
Nelson , SJ | 1 |
Fountas, KN | 1 |
Kapsalaki, EZ | 1 |
Gotsis, SD | 1 |
Kapsalakis, JZ | 1 |
Smisson , HF | 1 |
Johnston, KW | 1 |
Robinson, JS | 1 |
Papadakis, N | 1 |
Verhey, L | 1 |
Son, BC | 1 |
Kim, MC | 1 |
Choi, BG | 1 |
Kim, EN | 1 |
Baik, HM | 1 |
Choe, BY | 1 |
Kang, JK | 1 |
Hall, WA | 1 |
Martin, AJ | 1 |
Truwit, CL | 1 |
Ziegler, A | 2 |
von Kienlin , M | 1 |
Décorps, M | 1 |
Rémy, C | 2 |
Ishimaru, H | 1 |
Morikawa, M | 1 |
Iwanaga, S | 1 |
Kaminogo, M | 1 |
Ochi, M | 1 |
Hayashi, K | 1 |
García-Martín, ML | 1 |
Hérigault, G | 1 |
Farion, R | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Prospective Study About the Validity of MRS-guided Resection on Prognosis High-grade Gliomas[NCT02795364] | 50 participants (Anticipated) | Interventional | 2016-06-30 | Not yet recruiting | |||
Multi-paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases[NCT04626206] | 12 participants (Anticipated) | Observational | 2020-12-31 | Not yet recruiting | |||
Combination of 11C-MET PET and MRS in the Diagnosis of Glioma.[NCT03009318] | 100 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
Treatment Development of Triheptanoin for Glucose Transporter Type I Deficiency[NCT02021526] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2015-12-31 | Withdrawn (stopped due to NIH funding resulted in new clinical trial) | ||
Metabolic Characterization of Space Occupying Lesions of the Brain Using in Vivo MR- (Spectroscopic) Imaging at 3 Tesla and 7 Tesla[NCT04233788] | 55 participants (Anticipated) | Observational | 2021-09-01 | Recruiting | |||
Phase II Trial of Conventional Radiotherapy With Stereotactic Radiosurgery to High Risk Tumor Regions as Determined by Functional Imaging in Patients With Glioblastoma Multiforme[NCT00253448] | Phase 2 | 35 participants (Actual) | Interventional | 2002-12-31 | Completed | ||
Role of Glutamate-mediate Excitotoxicity in Invasion and Progression Processes of Glioblastoma Multiforme[NCT05775458] | 50 participants (Anticipated) | Observational | 2020-06-01 | Recruiting | |||
In Vivo Proton MR Spectroscopy of Brain Metastases Obtained at 1,5T and 3T.[NCT00184353] | 19 participants (Actual) | Observational | 2003-11-30 | Completed | |||
Ependymomics: Multiomic Approach to Radioresistance of Ependymomas in Children and Adolescents[NCT05151718] | 370 participants (Anticipated) | Observational | 2021-09-30 | Recruiting | |||
Study of Clinical Biomarkers in Human Health and Disease (Healthiomics)[NCT05106725] | 3,500 participants (Anticipated) | Observational | 2021-10-11 | Recruiting | |||
A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors[NCT00001574] | 40 participants (Actual) | Observational | 1997-03-14 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Followed every 3 months for 2 years, every 6 months for 3 years, and annually thereafter for at least 5 years (NCT00253448)
Timeframe: Minimum of 5 years.
Intervention | months (Median) | ||||||
---|---|---|---|---|---|---|---|
Entire Cohort | RTOG Glioma Recursive Partitioning Class 3 n=4 | RTOG Glioma Recursive Partitioning Class 4 n=13 | RTOG Glioma Recursive Partitioning Class 5 n=16 | RTOG Glioma Recursive Partitioning Class 6 n=2 | Patients receiving concurrent chemotherapy | Patients who were not candidates for chemotherapy | |
Stereotactic Radiosurgery Plus Conventional Radiotherapy | 15.8 | 22 | 18.7 | 12.5 | 3.9 | 20.8 | 11 |
19 reviews available for aspartic acid and Brain Neoplasms
Article | Year |
---|---|
Unique magnetic resonance spectroscopy profile of intracranial meningiomas compared to gliomas: a systematic review.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Spectr | 2023 |
Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2023 |
The diagnostic performance of magnetic resonance spectroscopy in differentiating high-from low-grade gliomas: A systematic review and meta-analysis.
Topics: Area Under Curve; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Databases, Factual; Glioma; Hum | 2016 |
Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis.
Topics: Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Hum | 2016 |
Vanishing pineal mass in a young patient without therapy: Case report and review of the literature.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Choline; Electroencephalography; Female; Glutamic Acid; | 2016 |
Clinical magnetic resonance spectroscopy of the central nervous system.
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Central Nervous System; Choline; Creatine; Glutamic | 2016 |
Proton magnetic resonance spectroscopy imaging in the study of human brain cancer.
Topics: Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Glioblastoma; Humans; In | 2009 |
[Magnetic resonance spectroscopy for cerebral imaging].
Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea | 2010 |
The role of MR spectroscopy in neurooncology.
Topics: Aspartic Acid; Biomarkers, Tumor; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Humans; Inosi | 2012 |
Potential of MR spectroscopy for assessment of glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Inositol; Lactates; Lipid Metabol | 2013 |
Glioblastoma with the appearance of arteriovenous malformation: pitfalls in diagnosis.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Child; Choline; Diagnosis, | 2013 |
3 Tesla magnetic resonance spectroscopy: cerebral gliomas vs. metastatic brain tumors. Our experience and review of the literature.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diagnosis, Differ | 2013 |
MR spectroscopy of brain tumors.
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Humans; Lipids; Magnetic Resonance Spectro | 2003 |
Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.
Topics: Alanine; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glutamic Acid; Glutamine; Humans | 2004 |
Proton MR spectroscopy of the brain at 3 T: an update.
Topics: Artifacts; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Cerebral Cortex; Choline; Creatine | 2007 |
Brain stem involvement in children with neurofibromatosis type 1: role of magnetic resonance imaging and spectroscopy in the distinction from diffuse pontine glioma.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Choline; Creatine; | 1997 |
[Mapping of cerebral metabolism on cerebral disorders using multi-slice proton magnetic resonance spectroscopic imaging].
Topics: Aspartic Acid; Brain; Brain Neoplasms; Cerebral Infarction; Choline; Creatinine; Humans; Lactates; M | 1997 |
Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Choline; Humans; Infant; Lacti | 1998 |
Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Energy Metabolism; Glioblastoma; Humans; Lactates; | 1992 |
14 trials available for aspartic acid and Brain Neoplasms
Article | Year |
---|---|
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Be | 2013 |
Evaluation of the lactate-to-N-acetyl-aspartate ratio defined with magnetic resonance spectroscopic imaging before radiation therapy as a new predictive marker of the site of relapse in patients with glioblastoma multiforme.
Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Crea | 2014 |
Prospective serial proton MR spectroscopic assessment of response to tamoxifen for recurrent malignant glioma.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Dis | 2008 |
Phase II trial of radiosurgery to magnetic resonance spectroscopy-defined high-risk tumor volumes in patients with glioblastoma multiforme.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Choline; Combined Modality Therapy; | 2012 |
Metabolic response of glioblastoma to superselective intra-arterial cerebral infusion of bevacizumab: a proton MR spectroscopic imaging study.
Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aspartic Acid; Bevacizumab; Brain; | 2012 |
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid | 2003 |
Distinction between high-grade gliomas and solitary metastases using peritumoral 3-T magnetic resonance spectroscopy, diffusion, and perfusion imagings.
Topics: Adult; Aged; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Cerebrovascular Circulation; Choli | 2004 |
Correlation of magnetic resonance spectroscopic and growth characteristics within Grades II and III gliomas.
Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Apoptosis; Aspartic Acid; Brain Neoplasms; Cell Pro | 2007 |
[Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Chol | 2007 |
Multivoxel 3D proton MR spectroscopy in the distinction of recurrent glioma from radiation injury.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Fema | 2007 |
Evaluation of invasiveness of astrocytoma using 1H-magnetic resonance spectroscopy: correlation with expression of matrix metalloproteinase-2.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Hum | 2007 |
Proton magnetic resonance spectroscopic imaging in newly diagnosed glioblastoma: predictive value for the site of postradiotherapy relapse in a prospective longitudinal study.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Choline; Female; Glioblastoma; Humans; Magnetic Resonance Ima | 2008 |
[Quantification of brain metabolites by 1H spectroscopy using cyclohexane as an external reference].
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Cyclohexanes; Female; Humans; | 1996 |
Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy.
Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Aspartic Acid; Brain Neoplasms; Child; C | 2000 |
279 other studies available for aspartic acid and Brain Neoplasms
Article | Year |
---|---|
Magnetic resonance spectroscopy - its added value in brain glioma multiparametric assessment.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectro | 2021 |
N-acetyl l-aspartate and Triacetin modulate tumor suppressor MicroRNA and class I and II HDAC gene expression induce apoptosis in Glioblastoma cancer cells in vitro.
Topics: Apoptosis; Aspartic Acid; Brain Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression | 2021 |
Revisiting the use of proton magnetic resonance spectroscopy in distinguishing between primary and secondary malignant tumors of the central nervous system.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Humans; Magnetic Resonance Spectroscopy; Proton M | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Diagnostic performance of MRI perfusion and spectroscopy for brainstem glioma grading.
Topics: Aspartic Acid; Brain Neoplasms; Brain Stem; Child; Choline; Creatine; Glioma; Humans; Magnetic Reson | 2022 |
Is pre-radiotherapy metabolic heterogeneity of glioblastoma predictive of progression-free survival?
Topics: Aspartic Acid; Brain Neoplasms; Choline; Glioblastoma; Humans; Lactates; Magnetic Resonance Imaging; | 2023 |
2-D magnetic resonance spectroscopic imaging of the pediatric brain using compressed sensing.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Co | 2019 |
A method for cranial target delineation in radiotherapy treatment planning aided by single-voxel magnetic resonance spectroscopy: evaluation using a custom-designed gel-based phantom and simulations.
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Humans; Magnetic Resonance Spect | 2019 |
The Association between Whole-Brain MR Spectroscopy and IDH Mutation Status in Gliomas.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Isocitrate | 2020 |
Neurometabolic Remodeling in Chronic Hiv Infection: a Five-Year Follow-up Multi-Voxel Mrs Study.
Topics: Adult; Algorithms; Anti-HIV Agents; Aspartic Acid; Brain; Brain Neoplasms; Cell Communication; Cell | 2019 |
Radiation Necrosis Following Stereotactic Radiosurgery for Trigeminal Neuralgia.
Topics: Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnostic Err | 2020 |
Correlations between DTI-derived metrics and MRS metabolites in tumour regions of glioblastoma: a pilot study.
Topics: Anisotropy; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Contrast Media; Creatine; Di | 2020 |
Multimodal MR Features of 8 Cases of Epithelioid Glioblastoma.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Cerebrovascular Circulation; Choline; Creatine; Diffusi | 2020 |
Hyperpolarized
Topics: Aerobiosis; Animals; Aspartic Acid; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Glioblastoma | 2021 |
Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytes; Brain Neoplasms; Female; Glioma; Glutamic | 2021 |
Early Detection of Radiation-Induced Injury and Prediction of Cognitive Deficit by MRS Metabolites in Radiotherapy of Low-Grade Glioma.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Cognitive Dysfunction; Creatine; Early Diagnosis; | 2021 |
[Magnetic resonance spectroscopy of brain tumors].
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Imaging | 2017 |
Mapping an Extended Neurochemical Profile at 3 and 7 T Using Accelerated High-Resolution Proton Magnetic Resonance Spectroscopic Imaging.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Female; Humans; Magnetic Resonance Spectroscopy; Male; | 2017 |
Age, choline-to-N-acetyl aspartate, and lipids-lactate-to-creatine ratios assemble a significant Cox's proportional-hazards regression model for survival prediction in patients with high-grade gliomas.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Lactic Acid; Lipids; Magnetic Res | 2017 |
Exploring the optimal ratio of d-glucose/l-aspartic acid for targeting carbon dots toward brain tumor cells.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Carbon; Cell Line, Tumor; Flow Cytometry; Glucose; Mice; Ph | 2018 |
In vivo characterization of brain metabolism by
Topics: Adaptor Proteins, Signal Transducing; Animals; Aspartic Acid; Brain; Brain Neoplasms; Cell Line, Tum | 2018 |
Cho/Cr ratio at MR spectroscopy as a biomarker for cellular proliferation activity and prognosis in glioma: correlation with the expression of minichromosome maintenance protein 2.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Neoplasms; Cell Proliferation; Chil | 2019 |
Variation of T
Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Child; Choline; Creatine; Female; Humans; Magnet | 2019 |
Imaging biomarkers from multiparametric magnetic resonance imaging are associated with survival outcomes in patients with brain metastases from breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Breast Neopla | 2018 |
On the relation between MR spectroscopy features and the distance to MRI-visible solid tumor in GBM patients.
Topics: Algorithms; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Healthy Volunteers; Hu | 2018 |
Lesion segmentation for MR spectroscopic imaging using the convolution difference method.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Computer Simulation; Glio | 2019 |
The Role of Single Voxel MR Spectroscopy, T2 Relaxation Time and Apparent Diffusion Coefficient in Determining the Cellularity of Brain Tumors by MATLAB Software
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Choline; Creatine; Cross-Sec | 2018 |
Incorporation of a spectral model in a convolutional neural network for accelerated spectral fitting.
Topics: Algorithms; Artifacts; Aspartic Acid; Brain Mapping; Brain Neoplasms; Choline; Computer Graphics; Cr | 2019 |
A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.
Topics: Adult; Aspartic Acid; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Glutamine; Gl | 2013 |
Utility of proton MR spectroscopy for differentiating typical and atypical primary central nervous system lymphomas from tumefactive demyelinating lesions.
Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Demyelinating Diseases; Diagnosis, Differential | 2014 |
Primary central neurocytoma of the mesencephalic tectum in a pediatric patient.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Humans; Magnetic Resonance Imaging; Magnetic Resonance S | 2014 |
Proton magnetic resonance spectroscopy and apparent diffusion coefficient in evaluation of solid brain lesions.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Diffusion | 2013 |
Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.
Topics: Amidohydrolases; Animals; Antifungal Agents; Aspartic Acid; Astrocytes; Brain; Brain Neoplasms; Cell | 2014 |
Spectroscopy imaging in intraoperative MR suite: tissue characterization and optimization of tumor resection.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Image | 2014 |
MR imaging of intracranial hemangiopericytomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Creatine; Female; Hema | 2014 |
3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; C | 2014 |
Delineation of gliomas using radial metabolite indexing.
Topics: Algorithms; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Diagnosis, Computer-Assisted | 2014 |
Proton T2 measurement and quantification of lactate in brain tumors by MRS at 3 Tesla in vivo.
Topics: Adult; Aged; Artifacts; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Female; | 2015 |
Volumetric spectroscopic imaging of glioblastoma multiforme radiation treatment volumes.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Brain Mapping; Brain Neoplasms; Choline; Creatine; F | 2014 |
Pilocytic astrocytoma with anaplastic features presenting good long-term clinical course after surgery alone: a case report.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Humans; Magnetic Resonance Imaging; Magnetic Res | 2015 |
Multivoxel proton magnetic resonance spectroscopy of inflammatory and neoplastic lesions of the canine brain at 3.0 T.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, | 2014 |
Germinoma in the bilateral basal ganglia presented with cognitive deterioration.
Topics: Adolescent; Aspartic Acid; Basal Ganglia; Brain Neoplasms; Cognition Disorders; Creatine; Germinoma; | 2015 |
Influence of echo time in quantitative proton MR spectroscopy using LCModel.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Image Processing, Computer | 2015 |
Prediction of anaplastic transformation in low-grade oligodendrogliomas based on magnetic resonance spectroscopy and 1p/19q codeletion status.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Chromosome Deletion; Chromosomes, Human, Pair | 2015 |
Quantification of serial changes in cerebral blood volume and metabolism in patients with recurrent glioblastoma undergoing antiangiogenic therapy.
Topics: Angiogenesis Inhibitors; Aspartic Acid; Bevacizumab; Blood Volume; Brain; Brain Mapping; Brain Neopl | 2015 |
Magnetic resonance spectroscopy of enhancing cerebral lesions: analysis of 78 histopathology proven cases.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; | 2014 |
Machine learning methods for the classification of gliomas: Initial results using features extracted from MR spectroscopy.
Topics: Algorithms; Artificial Intelligence; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Cre | 2015 |
Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Aspartic Acid; Brain Neoplasms; Cell Line, Tumo | 2015 |
Gene mutation profiling of primary glioblastoma through multiple tumor biopsy guided by 1H-magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Codon, Nonsense; DNA | 2015 |
Accurate grading of brain gliomas by soft independent modeling of class analogy based on non-negative matrix factorization of proton magnetic resonance spectra.
Topics: Algorithms; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glycine; Humans; Neoplasm Gra | 2016 |
Dynamic 1H-MRS assessment of brain tumors: a novel approach for differential diagnosis of glioma.
Topics: Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Case-Control Studies; Choline; Diagnosis, Differe | 2015 |
Comparison between magnetic resonance spectroscopy and diffusion weighted imaging in the evaluation of gliomas response after treatment.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Choline; Diffusion Magnetic Resonanc | 2015 |
Hippocampal proton MR spectroscopy as a novel approach in the assessment of radiation injury and the correlation to neurocognitive function impairment: initial experiences.
Topics: Aged; Aspartic Acid; Biomarkers; Brain Neoplasms; Cognition Disorders; Cranial Irradiation; Female; | 2015 |
Metabolic approach for tumor delineation in glioma surgery: 3D MR spectroscopy image-guided resection.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Diffusion Tensor Imaging; Feasibility S | 2016 |
Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Cell Differentiation; Glioma; Gray Matter; Humans; Lipid Meta | 2016 |
Whole-brain spectroscopic MRI biomarkers identify infiltrating margins in glioblastoma patients.
Topics: Aminolevulinic Acid; Aspartic Acid; Biomarkers; Brain; Brain Neoplasms; Cell Count; Choline; Disease | 2016 |
Evaluation of intracranial neoplasia and noninfectious meningoencephalitis in dogs by use of short echo time, single voxel proton magnetic resonance spectroscopy at 3.0 Tesla.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Case-Control Studies; Creatine; Dog Diseases; Dogs; Female; | 2016 |
Noninvasive evaluation of radiation-enhanced glioma cells invasiveness by ultra-high-field (1)H-MRS in vitro.
Topics: Aspartic Acid; Brain Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Choline; C | 2016 |
Advanced MRI increases the diagnostic accuracy of recurrent glioblastoma: Single institution thresholds and validation of MR spectroscopy and diffusion weighted MR imaging.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Cohort Studies; Diffusion Magnetic Resonance I | 2016 |
Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Computational Biology; Creatine; Fem | 2016 |
Will Ambient Ionization Mass Spectrometry Become an Integral Technology in the Operating Room of the Future?
Topics: Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Clinical Laboratory Techniques; Humans; Operating | 2016 |
MRS of pilocytic astrocytoma: The peak at 2 ppm may not be NAA.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Preschool; Humans; Inf | 2017 |
Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Chol | 2016 |
Choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios together with age assemble a significant Cox's proportional-hazards regression model for prediction of survival in high-grade gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Cre | 2016 |
Post-WBRT cognitive impairment and hippocampal neuronal depletion measured by in vivo metabolic MR spectroscopy: Results of prospective investigational study.
Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Cognitive Dysfunction; Cranial Irradiation; Female; Foll | 2017 |
Changes in cerebral metabolism during ketogenic diet in patients with primary brain tumors:
Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Cere | 2017 |
Multiparametric MR Imaging of Diffusion and Perfusion in Contrast-enhancing and Nonenhancing Components in Patients with Glioblastoma.
Topics: Adult; Aged; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Contrast Media; Diffusion Tensor I | 2017 |
Preliminary characterization of an experimental breast cancer cells brain metastasis mouse model by MRI/MRS.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Cell Line, Tumor; Choline; Creatine; Female; Humans; Magnet | 2008 |
Comparison of T(1) and T(2) metabolite relaxation times in glioma and normal brain at 3T.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Gliom | 2008 |
Spectrum separation resolves partial-volume effect of MRSI as demonstrated on brain tumor scans.
Topics: Algorithms; Aspartic Acid; Brain Neoplasms; Choline; Humans; Image Enhancement; Image Interpretation | 2008 |
[The advantage of photon magnetic resonance spectroscopy in brain tumors].
Topics: Abnormalities, Radiation-Induced; Aspartic Acid; Brain Neoplasms; Cell Proliferation; Choline; Creat | 2008 |
Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM.
Topics: Adult; Aged; Aspartic Acid; Brain Mapping; Brain Neoplasms; Choline; Creatine; Diagnosis, Differenti | 2009 |
Bilateral thalamic glioma.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Glioma; Humans; Magnetic Resonance Imagin | 2008 |
Proton MR spectroscopy improves discrimination between tumor and pseudotumoral lesion in solid brain masses.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Diagnosis, Differe | 2009 |
Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Diagnosis, Differential; Gangliogli | 2009 |
Developing a clinical decision model: MR spectroscopy to differentiate between recurrent tumor and radiation change in patients with new contrast-enhancing lesions.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Contrast | 2009 |
Metabolic alterations: a biomarker for radiation-induced normal brain injury-an MR spectroscopy study.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Humans; Magnetic Reso | 2009 |
Late-onset obsessive compulsive disorder associated with possible gliomatosis cerebri.
Topics: Aged; Anticonvulsants; Aspartic Acid; Brain Neoplasms; Choline; Corpus Callosum; Dominance, Cerebral | 2009 |
Computation of brain metabolite ratios in single-voxel proton MR spectroscopy: comparison between semiautomatic and automatic software.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Humans; Image Processing, C | 2010 |
(1)H spectroscopic imaging of human brain at 3 Tesla: comparison of fast three-dimensional magnetic resonance spectroscopic imaging techniques.
Topics: Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Contrast Media; Creatine; Echo-Planar | 2009 |
MR spectroscopic evaluation of brain tissue damage after treatment for pediatric brain tumors.
Topics: Adolescent; Aspartic Acid; Brain; Brain Neoplasms; Child; Choline; Creatine; Ependymoma; Female; Gli | 2010 |
Magnetic resonance spectroscopic evaluation of brain tissue metabolism after irradiation for pediatric brain tumors in long-term survivors: a report of two cases.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Humans; Lactic Acid; Ma | 2010 |
Distinction between glioma progression and post-radiation change by combined physiologic MR imaging.
Topics: Adult; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Cerebrovascular Circulation; Choline; Cr | 2010 |
MR spectroscopy for differentiation of recurrent glioma from radiation-induced changes.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Contrast | 2009 |
Spatial spectral modeling for robust MRSI.
Topics: Aspartic Acid; Brain Neoplasms; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imag | 2009 |
Grid-free interactive and automated data processing for MR chemical shift imaging data.
Topics: Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Case-Control Studies; Choline; Creatine; Elect | 2010 |
Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Contrast Media; | 2010 |
Response to article "Proton magnetic resonance spectroscopy in the distinction of high-grade cerebral gliomas from single metastatic brain tumors".
Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Creatinine; Edema; Glioma; Humans; Image Enhanc | 2010 |
Response to a letter by Paul E. Sijens.
Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Creatinine; Edema; Glioma; Humans; Image Enhanc | 2010 |
Gliomatosis cerebri, imaging findings of 12 cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Child; Choline; Creatine | 2010 |
A clinical and magnetic resonance spectroscopy study of a brain tumor in a patient with segmental neurofibromatosis.
Topics: Adolescent; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Humans; Lactates; Ma | 2010 |
Magnetic resonance spectroscopic imaging for visualization of the infiltration zone of glioma.
Topics: Adult; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Choline; Data Interpretation, Statistica | 2011 |
Measurements of diagnostic examination performance using quantitative apparent diffusion coefficient and proton MR spectroscopic imaging in the preoperative evaluation of tumor grade in cerebral gliomas.
Topics: Area Under Curve; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Im | 2011 |
N-Acetyl peak in MR spectra of intracranial metastatic mucinous adenocarcinomas.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Diagn | 2010 |
Metabolism and regional cerebral blood volume in autoimmune inflammatory demyelinating lesions mimicking malignant gliomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Blood Volume; Brain Neoplasms; Cerebrovas | 2011 |
Biopsy targeting gliomas: do functional imaging techniques identify similar target areas?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Biopsy; Brain Neoplasms; Choline; Contras | 2010 |
Noninvasive evaluation of cerebral glioma grade by using multivoxel 3D proton MR spectroscopy.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Creatine; Female; Glioma; H | 2011 |
Influence of brain tumors on the MR spectra of healthy brain tissue.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Neoplasms; Female; Humans; Magnetic Resonance | 2011 |
Value of 1H-magnetic resonance spectroscopy chemical shift imaging for detection of anaplastic foci in diffusely infiltrating gliomas with non-significant contrast-enhancement.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioma; H | 2011 |
[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma].
Topics: Adult; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; F | 2011 |
[2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells.
Topics: 3-Hydroxybutyric Acid; Animals; Aspartic Acid; Astrocytes; Brain Neoplasms; Citric Acid Cycle; Diet, | 2011 |
Predicting the outcome of grade II glioma treated with temozolomide using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Brain Neoplasms; Choline; Creatine; D | 2011 |
Predicting outcome of children with diffuse intrinsic pontine gliomas using multiparametric imaging.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Brain Stem Neoplasms; Child; Child, Preschool; Ch | 2011 |
Slowly progressive Parkinson syndrome due to thalamic butterfly astrocytoma.
Topics: Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Brain Stem; Choline; Glial Fibrillary Acidic Prot | 2011 |
MR spectroscopy using normalized and non-normalized metabolite ratios for differentiating recurrent brain tumor from radiation injury.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Diagn | 2011 |
Glioma residual or recurrence versus radiation necrosis: accuracy of pentavalent technetium-99m-dimercaptosuccinic acid [Tc-99m (V) DMSA] brain SPECT compared to proton magnetic resonance spectroscopy (1H-MRS): initial results.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Follow-Up Studie | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Topics: Algorithms; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioma; | 2012 |
Compressive sensing could accelerate 1H MR metabolic imaging in the clinic.
Topics: Algorithms; Analysis of Variance; Aspartic Acid; Brain Neoplasms; Choline; Citric Acid; Creatine; Da | 2012 |
N-acetyl peak in proton MR spectroscopy of metastatic mucinous adenocarcinoma of brain.
Topics: Adenocarcinoma, Mucinous; Adult; Aspartic Acid; Biomarkers, Tumor; Brain Chemistry; Brain Neoplasms; | 2013 |
Progressive multifocal leukoencephalopathy (PML) mimicking high-grade glioma on delayed F-18 FDG PET imaging.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Fluorodeoxy | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
The relationship between Cho/NAA and glioma metabolism: implementation for margin delineation of cerebral gliomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Choline; Female; Glioma; Hu | 2012 |
Magnetic resonance imaging of solitary brain metastases: main findings of nonmorphological sequences.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Aspartic Acid; Blood Volume; Brain | 2012 |
Multimodal MR imaging findings of a congenital glioblastoma multiforme.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Female; Glioblastoma; Humans; Infant; Magnetic Resonance Imag | 2012 |
Preoperative assessment using multimodal functional magnetic resonance imaging techniques in patients with brain gliomas.
Topics: Adolescent; Adult; Aged; Anisotropy; Aspartic Acid; Brain Neoplasms; Cerebral Cortex; Child; Choline | 2012 |
Differentiation of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy, diffusion and perfusion metrics at 3 T.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Diagnosis, D | 2012 |
Differentiating diffuse World Health Organization grade II and IV astrocytomas with ex vivo magnetic resonance spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Fema | 2013 |
Conservative management of presumed low-grade gliomas in the asymptomatic pediatric population.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Asymptomatic Diseases; Brain Neoplasms; Child; Child, Presch | 2014 |
1H chemical shift imaging characterization of human brain tumor and edema.
Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Choline; Creatine; Humans; Hydrogen; Magnetic Resonance | 2002 |
Brain abscess and glioblastoma identified by combined proton magnetic resonance spectroscopy and diffusion-weighted magnetic resonance imaging--two case reports.
Topics: Acetates; Adult; Amino Acids; Aspartic Acid; Brain Abscess; Brain Neoplasms; Diagnosis, Differential | 2002 |
Proton MR spectroscopy of tumefactive demyelinating lesions.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Demyelinating Diseases; Diagnosis, Different | 2002 |
The contribution of proton magnetic resonance spectroscopy (1HMRS) to clinical brain tumour diagnosis.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatinine; Humans; Inositol; Magn | 2002 |
Histopathological validation of a three-dimensional magnetic resonance spectroscopy index as a predictor of tumor presence.
Topics: Aspartic Acid; Biopsy; Brain Neoplasms; Choline; Glioma; Humans; Magnetic Resonance Spectroscopy; Pr | 2002 |
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi | 2003 |
High-resolution 3D proton spectroscopic imaging of the human brain at 3 T: SNR issues and application for anatomy-matched voxel sizes.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Humans; Imaging, Three-Dime | 2003 |
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat | 2003 |
[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors].
Topics: Aspartic Acid; Biomarkers; Brain Abscess; Brain Neoplasms; Choline; Computer Graphics; Creatine; Dia | 2002 |
1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Fo | 2003 |
Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma.
Topics: Antigens, CD; Antigens, Surface; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Cell Nucleus; Ch | 2003 |
1H-MR spectroscopy of normal brain tissue before and after postoperative radiotherapy because of primary brain tumors.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Combined Modality Therapy; Female; Humans; | 2003 |
Multifocal inflammatory leukoencephalopathy: use of thallium-201 SPECT and proton MRS.
Topics: Adjuvants, Immunologic; Antimetabolites, Antineoplastic; Aspartic Acid; Axons; Biopsy; Brain; Brain | 2003 |
Monitoring individual response to brain-tumour chemotherapy: proton MR spectroscopy in a patient with recurrent glioma after stereotactic radiotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Astrocytoma; Brain Neoplasms; | 2004 |
A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Cerebrospinal Fluid; Choline; Creatine; Disc | 2003 |
Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain Neoplasms; Bromodeoxyu | 2004 |
[Magnetic resonance imaging spectroscopy. Part 1: Basics].
Topics: Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Choline; Energy Metabolism; Humans; Image Enh | 2003 |
Spectroscopic and perfusion magnetic resonance imaging predictors of progression in pediatric brain tumors.
Topics: Adolescent; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Child; Child, Preschool; Choline; Disea | 2004 |
1H-MRSI of radiation effects in normal-appearing white matter: dose-dependence and impact on automated spectral classification.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Dose-Response Relationshi | 2004 |
Survival analysis in patients with glioblastoma multiforme: predictive value of choline-to-N-acetylaspartate index, apparent diffusion coefficient, and relative cerebral blood volume.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Blood Volume; Brain Neoplasms; Choline; Glioblastoma; Humans | 2004 |
Evaluation of the response of metastatic brain tumors to stereotactic radiosurgery by proton magnetic resonance spectroscopy, 201TlCl single-photon emission computerized tomography, and gadolinium-enhanced magnetic resonance imaging.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Neoplasms; Choline; Contrast Media; Fema | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; C | 2004 |
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
Topics: Adult; Aged; Aspartic Acid; Body Water; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2004 |
Proton magnetic resonance spectroscopy imaging in the evaluation of patients undergoing gamma knife surgery for Grade IV glioma.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Cohor | 2004 |
Proton magnetic resonance spectroscopic imaging in pediatric pilomyxoid astrocytoma.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child, Preschool; Choline; Creatine; Female; Humans; In | 2005 |
Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas.
Topics: Adult; Algorithms; Aspartic Acid; Astrocytoma; Automation; Biopsy; Brain Chemistry; Brain Mapping; B | 2004 |
Noninvasive magnetic resonance spectroscopic imaging biomarkers to predict the clinical grade of pediatric brain tumors.
Topics: Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Femal | 2004 |
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatin | 2005 |
Proton MRS of the peritumoral brain.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Edema; Brain Neoplasms; Epilepsy; Female; Huma | 2005 |
Clinicopathological examination of glioma by proton magnetic resonance spectroscopy background.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Choline; Female; Glioma; Humans; Lactic Acid; Magnetic Resona | 2004 |
Early metabolic changes in metastatic brain tumors after Gamma Knife radiosurgery: 1H-MRS study.
Topics: Aged; Aspartic Acid; Brain Neoplasms; Creatine; Female; Glycerylphosphorylcholine; Humans; Lactic Ac | 2004 |
Multimodal metabolic imaging of cerebral gliomas: positron emission tomography with [18F]fluoroethyl-L-tyrosine and magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Child; Child, Preschool; Cho | 2005 |
Spectroscopy and navigation.
Topics: Algorithms; Aspartic Acid; Brain; Brain Neoplasms; Choline; Glioma; Humans; Image Processing, Comput | 2005 |
Proton magnetic resonance spectroscopic imaging integrated into image-guided surgery: correlation to standard magnetic resonance imaging and tumor cell density.
Topics: Algorithms; Aspartic Acid; Biopsy; Brain Neoplasms; Cell Count; Choline; Feasibility Studies; Glioma | 2005 |
Characterization of brain tumors by MRS, DWI and Ki-67 labeling index.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Cell Proliferation; Choline; Creatinine; Diffusion Magn | 2005 |
[A case of high grade astrocytoma arising in the hand area of precentral gyrus].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Astrocytoma; Brain Neoplasms; | 2005 |
Multisection 1H magnetic resonance spectroscopic imaging assessment of glioma response to chemotherapy.
Topics: Adult; Antineoplastic Agents; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Disease-Free Surviv | 2006 |
Can MR spectroscopy ever be simple and effective?
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Humans; Magnetic Resonance Spectroscopy | 2005 |
Evaluation of treatment-induced cerebral white matter injury by using diffusion-tensor MR imaging: initial experience.
Topics: Adult; Aged; Anisotropy; Antineoplastic Agents; Aspartic Acid; Brain; Brain Chemistry; Brain Neoplas | 2005 |
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glio | 2005 |
Differentiation between brain tumor recurrence and radiation injury using MR spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Contrast Media; | 2005 |
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Choline; Chromium; Creatine; Gliobla | 2005 |
Multivoxel magnetic resonance spectroscopy in gliomatosis cerebri.
Topics: Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Humans; Magnetic | 2005 |
Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Case-Control Studies; Choline; Creatine; Female; | 2006 |
In vivo research in astrocytoma cell proliferation with 1H-magnetic resonance spectroscopy: correlation with histopathology and immunohistochemistry.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Choline; Creatine; Fema | 2006 |
[Application of (1)H MR spectroscopic imaging in radiation oncology: choline as a marker for determining the relative probability of tumor progression after radiation of glial brain tumors].
Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Choline; Combined | 2006 |
Multiparametric 3T MR approach to the assessment of cerebral gliomas: tumor extent and malignancy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Contrast Media; Creatine; Diffusio | 2006 |
Clinical 1H magnetic resonance spectroscopy of brain metastases at 1.5T and 3T.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Humans; Magnetic Resonance Spectro | 2006 |
Quantitation of NAA in the brain by magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Humans; Magnetic Resonance Spectroscopy; Mat | 2006 |
Leukoencephalopathy with bilateral anterior temporal lobe cysts.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Central Nervous System Cysts; Child; Child, Preschool; F | 2006 |
3T 1H-MR spectroscopy in grading of cerebral gliomas: comparison of short and intermediate echo time sequences.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Echo-Planar Imaging; Female; Glioma; | 2006 |
Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
Topics: Adult; Aged; Anisotropy; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Size; Choline; Cre | 2006 |
Long-term normal-appearing brain tissue monitoring after irradiation using proton magnetic resonance spectroscopy in vivo: statistical analysis of a large group of patients.
Topics: Adult; Aged; Aspartic Acid; Blood-Brain Barrier; Brain; Brain Neoplasms; Choline; Creatine; Female; | 2006 |
Comments and controversies: magnetic resonance spectroscopy and gliomas.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Humans; Magnetic Resonance Spectroscopy; | 2006 |
Proton magnetic resonance spectroscopy (MRS) of metastatic brain tumors: variations of metabolic profile.
Topics: Aged; Algorithms; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Evalua | 2006 |
Short echo time 1 H magnetic resonance spectroscopy of childhood brain tumours.
Topics: Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Female; Humans; Hydrogen | 2007 |
Distinction between recurrent glioma and radiation injury using magnetic resonance spectroscopy in combination with diffusion-weighted imaging.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Diffusion Magn | 2007 |
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases; | 2007 |
3.0-T functional brain imaging: a 5-year experience.
Topics: Artifacts; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Cerebral Arteries; Cerebral Cortex | 2007 |
1H MR spectroscopy in the assessment of gliomatosis cerebri.
Topics: Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Humans; Magnetic Resonance Imaging; Magn | 2007 |
Changes in fiber integrity, diffusivity, and metabolism of the pyramidal tract adjacent to gliomas: a quantitative diffusion tensor fiber tracking and MR spectroscopic imaging study.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Creatine; Diffusion Magnetic Resonance Ima | 2007 |
Multimodal MRI in the characterization of glial neoplasms: the combined role of single-voxel MR spectroscopy, diffusion imaging and echo-planar perfusion imaging.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Blood Flow Velocity; Brain; Brain Neoplasms; Choline | 2007 |
3D 1H MRSI of brain tumors at 3.0 Tesla using an eight-channel phased-array head coil.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Case-Control Studies; Choline; Creatine; Female; Humans | 2007 |
Monovoxel 1H magnetic resonance spectroscopy in the progression of gliomas.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Disease Progression; Female; Glioma; | 2007 |
Low-grade glioma: correlation of short echo time 1H-MR spectroscopy with 23Na MR imaging.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Female; Glioma; Humans; Magnetic Resonance Imaging; Ma | 2008 |
Giant infantile gliosarcoma: magnetic resonance imaging findings.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Child, Preschool; Choline; Creatinine; Female; Gliosarcoma; H | 2008 |
Mimicking the human expert: pattern recognition for an automated assessment of data quality in MR spectroscopic images.
Topics: Area Under Curve; Artifacts; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Expert Systems; Huma | 2008 |
Central nervous system lymphoma characterization by diffusion-weighted imaging and MR spectroscopy.
Topics: Adult; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differenti | 2008 |
Penetration of N-(phosphonacetyl)-L-aspartate into human central nervous system and intracerebral tumor.
Topics: Aspartic Acid; Brain Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infus | 1980 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminan | 1995 |
Brain lesions in patients with AIDS: H-1 MR spectroscopy.
Topics: Abscess; Adult; AIDS Dementia Complex; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Crea | 1995 |
Toxoplasmosis and primary central nervous system lymphoma in HIV infection: diagnosis with MR spectroscopy.
Topics: Adult; AIDS-Related Opportunistic Infections; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Dia | 1995 |
Analysis of brain tumors using 1H magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Glioblastoma; Humans; Lactates; Magneti | 1995 |
Characterization of intracranial mass lesions with in vivo proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Child; Choline; Crea | 1995 |
Radiation-induced changes in human brain metabolites as studied by 1H nuclear magnetic resonance spectroscopy in vivo.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Female; Humans; Magnetic Resona | 1995 |
Spectral editing with adiabatic pulses.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Carbon Isotopes; Choline; Creatine; Feasibility Studies; Gl | 1995 |
1H MR spectroscopy in patients with metastatic brain tumors: a multicenter study.
Topics: Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Female; Humans; Mag | 1995 |
Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Ependymoma; Glioma; Humans; Magnetic | 1995 |
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatin | 1994 |
Proton magnetic resonance spectroscopy of brain tumors: an in vitro study.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Neoplasms; Child; C | 1994 |
Brain abscess observed by localized proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain Abscess; Brain Chemistry; Brain Neoplasms; Choline; Contrast Media; Creatine; D | 1994 |
Incorporation of lactate measurement in multi-spin-echo proton spectroscopic imaging.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Humans; Image Processing, | 1995 |
Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation.
Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Cerebellar Di | 1995 |
High-resolution 1H-magnetic resonance spectroscopy of pediatric posterior fossa tumors in vitro.
Topics: Adolescent; Alanine; Amino Acids; Animals; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cerebellar N | 1994 |
[Clinical suitability of brain tumor patients for single voxel protein MR spectroscopy].
Topics: Aspartic Acid; Brain Neoplasms; Cell Division; Choline; Creatine; Energy Metabolism; Humans; Lactate | 1994 |
Effects of therapy on the 1H NMR spectrum of a human glioma line.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Lactates; Magnetic Resonance Spe | 1994 |
Proton MR spectroscopy of experimental brain tumors in vivo.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain Edema; Brain Neoplasms; Caudate Nucleus; Cell Line; Cho | 1994 |
Response of non-Hodgkin lymphoma to radiation therapy: early and long-term assessment with H-1 MR spectroscopic imaging.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Follow-Up Studies; Humans; Lipid Metaboli | 1995 |
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr | 1994 |
Localized proton spectroscopy of inoperable brain gliomas. Response to radiation therapy.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Glioma; Humans; Lactates; Lactic Acid; Magnetic Resonance I | 1993 |
Quantitative proton spectroscopy and histology of a canine brain tumor model.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Dogs; Glioma; Lactates; Lactic Acid; Mag | 1993 |
Incorporating lactate/lipid discrimination into a spectroscopic imaging sequence.
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Cerebrovascular Disorders; Humans; Lactates; Lipids | 1993 |
Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours.
Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellum; Creatine; Humans; Magnetic Resonance | 1995 |
[Spectroscopic imaging of the brain. Examination technique and clinical applications].
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Cerebral Infarction; Choline; Creatine; Energy M | 1995 |
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D | 1996 |
Single-voxel proton brain spectroscopy exam (PROBE/SV) in patients with primary brain tumors.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Chemistry; Brain Neoplasms; Choline; Crea | 1996 |
Reproducibility of metabolite peak areas in 1H MRS of brain.
Topics: Adult; Analysis of Variance; Artifacts; Aspartic Acid; Brain; Brain Neoplasms; Cerebrovascular Disor | 1996 |
Noninvasive evaluation of malignancy of brain tumors with proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Energy Metabolism; Femal | 1996 |
Intracranial tumors in children: small single-voxel proton MR spectroscopy using short- and long-echo sequences.
Topics: Adolescent; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Creatinine; Female; Gl | 1996 |
Hydrogen magnetic resonance spectroscopy follow-up after radiation therapy of human brain cancer. Unexpected inverse correlation between the changes in tumor choline level and post-gadolinium magnetic resonance imaging contrast.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Energy Metabolism; Follow-Up Studies; Four | 1995 |
Proton magnetic resonance spectroscopy and intracranial tumours: clinical perspectives.
Topics: Adenoma; Aspartic Acid; Brain Neoplasms; Choline; Craniopharyngioma; Creatinine; Glioma; Humans; Lym | 1996 |
1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Fourier Analysis; Gadolini | 1997 |
Multivoxel proton MR spectroscopy and hemodynamic MR imaging of childhood brain tumors: preliminary observations.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Femal | 1997 |
Brain tumors: localized H-1 MR spectroscopy at 0.5 T.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Case-Control Studi | 1997 |
Early changes in peritumorous oedema and contralateral white matter after dexamethasone: a study using proton magnetic resonance spectroscopy.
Topics: Antineoplastic Agents, Hormonal; Aspartic Acid; Brain; Brain Edema; Brain Neoplasms; Choline; Creati | 1997 |
[Metabolic imaging of human brain tumors: H-1 chemical shift imaging and PET].
Topics: Aspartic Acid; Brain; Brain Neoplasms; Choline; Humans; Lactates; Magnetic Resonance Spectroscopy; P | 1997 |
Evaluation of metabolic heterogeneity in brain tumors using 1H-chemical shift imaging method.
Topics: Aspartic Acid; Brain Neoplasms; Choline; Creatine; Evaluation Studies as Topic; Glioma; Humans; Imag | 1997 |
Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cell Transformation, Neoplas | 1997 |
Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy.
Topics: Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Disease Pro | 1997 |
Proton MR spectroscopy of delayed cerebral radiation in monkeys and humans after brachytherapy.
Topics: Adult; Animals; Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Cranial Irradiation; | 1997 |
Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neo | 1997 |
Transient metabolic changes observed with proton MR spectroscopy in normal human brain after radiation therapy.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactic Acid; Magnet | 1998 |
Application of proton chemical shift imaging in monitoring of gamma knife radiosurgery on brain tumors.
Topics: Adolescent; Adult; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Female; Humans; Lipids; Magnet | 1998 |
Treatment of brain tumors in children is associated with abnormal MR spectroscopic ratios in brain tissue remote from the tumor site.
Topics: Adolescent; Adult; Antineoplastic Agents; Aspartic Acid; Brain; Brain Neoplasms; Child; Child, Presc | 1998 |
In vivo lactate editing with simultaneous detection of choline, creatine, NAA, and lipid singlets at 1.5 T using PRESS excitation with applications to the study of brain and head and neck tumors.
Topics: Aspartic Acid; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactic Acid; Lip | 1998 |
Pediatric low-grade gliomas: prognosis with proton magnetic resonance spectroscopic imaging.
Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Division; Child; Child, Prescho | 1998 |
Intraoperative microdialysis and tissue-pO2 measurement in human glioma.
Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Cell Death; Female; Frontal Lobe; Glioblastoma; Glutami | 1998 |
Classification of biopsy-confirmed brain tumors using single-voxel MR spectroscopy.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Astrocytoma; Biopsy; Body Water; Brain Neoplasms; | 1999 |
[1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat.
Topics: Alanine; Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain; Brain Neopla | 1999 |
Three-dimensional multivoxel proton MR spectroscopy of the brain in children with neurofibromatosis type 1.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; | 1999 |
Regional age dependence of human brain metabolites from infancy to adulthood as detected by quantitative localized proton MRS.
Topics: Adolescent; Age Factors; Aspartic Acid; Basal Ganglia; Brain; Brain Neoplasms; Cerebellum; Child; Ch | 1999 |
Oligodendroglial gliomatosis cerebri: (1)H-MRS suggests elevated glycine/inositol levels.
Topics: Adult; Aspartic Acid; Biopsy, Needle; Brain Neoplasms; Glycine; Humans; Inositol; Magnetic Resonance | 1999 |
Using proton magnetic resonance spectroscopic imaging to predict in vivo the response of recurrent malignant gliomas to tamoxifen chemotherapy.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Hormonal; Aspartic Acid; Astro | 2000 |
Comparison of relative cerebral blood volume and proton spectroscopy in patients with treated gliomas.
Topics: Adult; Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Choline; Combined Modality Therapy; Fema | 2000 |
MR spectroscopy in gliomatosis cerebri.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Child; Choline; Creatine; Di | 2000 |
Effect of voxel position on single-voxel MR spectroscopy findings.
Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glio | 2000 |
Discrimination between neoplastic and nonneoplastic brain lesions by use of proton MR spectroscopy: the limits of accuracy with a logistic regression model.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Neoplasms; Choline; Diagnosi | 2000 |
Quantitative proton magnetic resonance spectroscopy of focal brain lesions.
Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; | 2000 |
Correlation of myo-inositol levels and grading of cerebral astrocytomas.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Chil | 2000 |
An automated technique for the quantitative assessment of 3D-MRSI data from patients with glioma.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Female; Glioma; Humans; Imaging, Three-Dimens | 2001 |
In vivo proton magnetic resonance spectroscopy of brain tumors.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Brain; Brain Abscess; Brain Neoplasms; Choline | 2000 |
Serial proton MR spectroscopic imaging of recurrent malignant gliomas after gamma knife radiosurgery.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Energy Metabolism; Female; Follow-Up Studies; | 2001 |
Proton magnetic resonance chemical shift imaging (1H CSI)-directed stereotactic biopsy.
Topics: Adult; Aspartic Acid; Biopsy, Needle; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Ene | 2001 |
An efficient chemical shift imaging scheme for magnetic resonance-guided neurosurgery.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Biopsy; Brain; Brain Mapping; Brain Neop | 2001 |
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; | 2001 |
Analysis of volume MRI and MR spectroscopic imaging data for the evaluation of patients with brain tumors.
Topics: Algorithms; Aspartic Acid; Brain Neoplasms; Choline; Computer Simulation; Creatine; Humans; Image Pr | 2001 |
Differentiation between high-grade glioma and metastatic brain tumor using single-voxel proton MR spectroscopy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chil | 2001 |
Mapping extracellular pH in rat brain gliomas in vivo by 1H magnetic resonance spectroscopic imaging: comparison with maps of metabolites.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Buffers; Choline; Contrast Media; Creatine; Extracellular S | 2001 |
Correlation between magnetic resonance spectroscopy imaging and image-guided biopsies: semiquantitative and qualitative histopathological analyses of patients with untreated glioma.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Dominance, Cerebr | 2001 |
[Brain tumors: interest of magnetic resonance spectroscopy for the diagnosis and the prognosis].
Topics: Aspartic Acid; Biopsy; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Energy Metabolism; | 2001 |
Diffusion-weighted in vivo localized proton MR spectroscopy of human cerebral ischemia and tumor.
Topics: Adult; Aspartic Acid; Brain Ischemia; Brain Neoplasms; Cerebral Infarction; Creatine; Diffusion; Fem | 2002 |
High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Blood Volume; Brain; Brain Chemistry; Bra | 2002 |
Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions.
Topics: Aspartic Acid; Brain Abscess; Brain Neoplasms; Cerebral Infarction; Choline; Creatine; Diagnosis, Di | 2002 |
Effects of amino acids on calcium uptake by glial and neuroblastoma cells.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Neoplasms; Calcimycin; Calcium; Clone Cells; Cricetinae; | 1979 |
[Amino acid composition of ventricular and lumbar cerebrospinal fluid in brain tumors].
Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Brain Neoplasms; Child; Child, Preschool; Glutamates; | 1977 |
Primitive neuroectodermal tumors after prophylactic central nervous system irradiation in children. Association with an activated K-ras gene.
Topics: Aspartic Acid; Base Sequence; Brain Neoplasms; Child; Child, Preschool; Codon; Female; Gene Expressi | 1992 |
Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevance.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Female; Glucose; | 1992 |
Proton magnetic resonance spectroscopy of pediatric brain tumors.
Topics: Adolescent; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Choline; Cre | 1992 |
Human brain tumors: spectral patterns detected with localized H-1 MR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Humans; Magnetic Resonance Spectroscopy; Midd | 1992 |
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques.
Topics: Acute Disease; Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; De | 1992 |
Spatially localized in vivo 1H magnetic resonance spectroscopy of an intracerebral rat glioma.
Topics: Animals; Aspartic Acid; Brain; Brain Neoplasms; Creatine; Female; Glioma; Hydrogen; Lactates; Lactic | 1992 |
[The clinical application of multi-voxel 1H-CSI (chemical shift imaging) in brain tumors].
Topics: Aspartic Acid; Brain Neoplasms; Humans; Lactates; Magnetic Resonance Spectroscopy | 1991 |
In vivo 1H-spectroscopy of human intracranial tumors at 1.5 tesla. Preliminary experience at a clinical installation.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactate | 1991 |
Noninvasive differentiation of tumors with use of localized H-1 spectroscopy in vivo: initial experience in patients with cerebral tumors.
Topics: Aspartic Acid; Brain; Brain Neoplasms; Diagnosis, Differential; Humans; Lactates; Magnetic Resonance | 1990 |
Detection of metabolic heterogeneity of human intracranial tumors in vivo by 1H NMR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Creatine; Glioma; Humans; Magnetic Resona | 1990 |
Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.
Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Cysts; | 1989 |
Pyrimidine pathways enzymes in human tumors of brain and associated tissues: potentialities for the therapeutic use of N-(phosphonacetyl-L-aspartate and 1-beta-D-arabinofuranosylcytosine.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Brain; Brain Neoplasms; Cytarabine; Cytidine Deaminas | 1987 |
Aspartame. Review of safety issues. Council on Scientific Affairs.
Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplas | 1985 |
Some biochemical characteristics of neuroglia as deduced by glial tumor biochemical analysis.
Topics: Aminobutyrates; Aspartic Acid; Astrocytoma; Brain; Brain Chemistry; Brain Neoplasms; Carboxy-Lyases; | 1971 |
N-acetyl-L-aspartic acid content of human neural tumours and bovine peripheral nervous tissues.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Cattle; Cerebral Cortex; Craniopharyngioma; Glioblastoma; G | 1972 |
[Activities of glutamate dehydrogenase and aspartate aminotransferase in human brain tumors].
Topics: Adenoma; Aspartate Aminotransferases; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Craniopha | 1972 |
Amino acid uptake into human brain tumors.
Topics: Absorption; Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Astrocytoma; Autoradiography; Brain | 1974 |
[Various low-molecular nitrogen compounds in experimental brain tumors in white mice].
Topics: Aminobutyrates; Ammonia; Animals; Aspartic Acid; Brain; Brain Neoplasms; Glutamates; Mice; Neoplasms | 1970 |