aspartic acid has been researched along with Brain Injuries in 117 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Semiquantitative analysis of NAA relative to creatine-containing compounds (Cr) and choline (Cho) was carried out from proton spectra obtained by means of chemical shift (CS) imaging and single-voxel (SV) methods in 25 patients with severe traumatic brain injuries (TBIs) (Glasgow Coma Scale scores < or = 8) using a 1." | 5.13 | Assessment of mitochondrial impairment in traumatic brain injury using high-resolution proton magnetic resonance spectroscopy. ( Aygok, GA; Bullock, RM; Fatouros, PP; Marmarou, A; Portella, G; Signoretti, S, 2008) |
| " We also did not find a correlation between the amount of Glx and the initial Glasgow Coma Scale score, duration of coma, nor with changes in spectral metabolites, including N-acetyl aspartate, choline, and myoinositol." | 3.72 | Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. ( Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K, 2004) |
| " We hypothesized that CSF glutamate, aspartate, and glycine would be increased after TBI in children and that these increases would be associated with age, child abuse, poor outcome, and cerebral ischemia." | 3.71 | Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse. ( Adelson, PD; Bell, MJ; Clark, RS; Graham, SH; Kochanek, PM; Marion, DW; Rose, ME; Ruppel, RA; Wisniewski, SR, 2001) |
| "The dominant theory that diffuse axonal injury is the main neuropathological process behind mTBI is being revealed as weak at best or inconclusive, given the current literature and the fact that neuronal injury inherent to mTBI improves, with few lasting clinical sequelae in the vast majority of patients." | 2.46 | Biochemical and neurochemical sequelae following mild traumatic brain injury: summary of experimental data and clinical implications. ( Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R, 2010) |
| "Early brain damage (EBI) following subarachnoid hemorrhage (SAH) is a long-lasting condition with a high occurrence." | 2.44 | Wu-zhu-yu Decoction reduces early brain injury following subarachnoid hemorrhage in vivo and in vitro by activating the Nrf2 antioxidant system via SIRT6 targeting. ( Gong, M; He, Z; Ling, X; Wang, W; Xu, M; Yue, Q, 2024) |
| "Eighty cases of nasopharyngeal cancer treated with radiotherapy within the same period underwent MRS imaging before or after radiotherapy." | 1.40 | Magnetic resonance spectroscopic imaging of brain injury after nasopharyngeal cancer radiation in early delayed reaction. ( Chen, WS; Hong, L; Li, CQ; Li, JJ; Wang, F; Xing, ZB; Zhang, JH, 2014) |
| "These four children all had seizure activity and abnormal initial neurological examinations and required admission to the PICU." | 1.33 | Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury. ( Ball, WS; Care, M; Cecil, KM; Makoroff, KL, 2005) |
| "Childhood obstructive sleep apnea (OSA) is associated with neuropsychological deficits of memory, learning, and executive function." | 1.33 | Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury. ( Barker, PB; Degaonkar, M; Earley, CJ; Halbower, AC; Mahone, EM; Marcus, CL; Prahme, MC; Smith, PL, 2006) |
| " The 20 mg/kg intravenous dose failed to ameliorate the biochemical damages while the 35 mg/kg dosage showed 36% NAA recovery and 39% ATP restoration (p < 0." | 1.32 | The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury. ( Amorini, AM; Dunbar, J; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (2.56) | 18.7374 |
| 1990's | 17 (14.53) | 18.2507 |
| 2000's | 58 (49.57) | 29.6817 |
| 2010's | 34 (29.06) | 24.3611 |
| 2020's | 5 (4.27) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, AM | 1 |
| Gerhalter, T | 1 |
| Dehkharghani, S | 1 |
| Peralta, R | 1 |
| Gajdošík, M | 2 |
| Tordjman, M | 1 |
| Zabludovsky, J | 1 |
| Sheriff, S | 1 |
| Ahn, S | 1 |
| Babb, JS | 6 |
| Bushnik, T | 1 |
| Zarate, A | 1 |
| Silver, JM | 2 |
| Im, BS | 1 |
| Wall, SP | 1 |
| Madelin, G | 1 |
| Kirov, II | 5 |
| Anazodo, UC | 1 |
| Wong, DY | 1 |
| Théberge, J | 1 |
| Dacey, M | 1 |
| Gomes, J | 1 |
| Penny, JD | 1 |
| van Ginkel, M | 1 |
| Poirier, SE | 1 |
| McIntyre, CW | 1 |
| Hao, FX | 1 |
| Zeng, MN | 1 |
| Cao, B | 1 |
| Liang, XW | 1 |
| Jiao, XM | 1 |
| Feng, WS | 1 |
| Zheng, XK | 1 |
| Xu, M | 1 |
| Yue, Q | 1 |
| He, Z | 1 |
| Ling, X | 1 |
| Wang, W | 1 |
| Gong, M | 1 |
| Yang, J | 1 |
| Gao, J | 1 |
| Han, D | 1 |
| Li, Q | 1 |
| Liao, C | 1 |
| Li, J | 1 |
| Wang, R | 1 |
| Luo, Y | 1 |
| Basu, SK | 1 |
| Pradhan, S | 1 |
| Kapse, K | 1 |
| McCarter, R | 1 |
| Murnick, J | 1 |
| Chang, T | 1 |
| Limperopoulos, C | 1 |
| Wagner, M | 1 |
| Jurcoane, A | 1 |
| Hildebrand, C | 1 |
| Güresir, E | 1 |
| Vatter, H | 1 |
| Zanella, FE | 1 |
| Berkefeld, J | 1 |
| Pilatus, U | 1 |
| Hattingen, E | 1 |
| O'Phelan, K | 1 |
| Ernst, T | 1 |
| Park, D | 1 |
| Stenger, A | 1 |
| Denny, K | 1 |
| Green, D | 1 |
| Chang, C | 1 |
| Chang, L | 1 |
| Hetherington, HP | 1 |
| Hamid, H | 1 |
| Kulas, J | 1 |
| Ling, G | 1 |
| Bandak, F | 1 |
| de Lanerolle, NC | 1 |
| Pan, JW | 1 |
| Sivák, Š | 1 |
| Bittšanský, M | 1 |
| Grossmann, J | 1 |
| Nosál', V | 1 |
| Kantorová, E | 1 |
| Siváková, J | 1 |
| Demková, A | 1 |
| Hnilicová, P | 1 |
| Dobrota, D | 1 |
| Kurča, E | 1 |
| Kierans, AS | 1 |
| Gonen, O | 6 |
| Haemer, G | 1 |
| Nisenbaum, E | 1 |
| Grossman, RI | 7 |
| Lui, YW | 3 |
| Di Pietro, V | 3 |
| Amorini, AM | 8 |
| Tavazzi, B | 9 |
| Vagnozzi, R | 8 |
| Logan, A | 1 |
| Lazzarino, G | 9 |
| Signoretti, S | 10 |
| Belli, A | 3 |
| Chen, WS | 1 |
| Li, JJ | 1 |
| Zhang, JH | 1 |
| Hong, L | 1 |
| Xing, ZB | 1 |
| Wang, F | 1 |
| Li, CQ | 1 |
| Fievisohn, EM | 1 |
| Sajja, VS | 2 |
| Vandevord, PJ | 1 |
| Hardy, WN | 1 |
| Hinzman, JM | 1 |
| DiNapoli, VA | 1 |
| Mahoney, EJ | 1 |
| Gerhardt, GA | 1 |
| Hartings, JA | 1 |
| Grossman, EJ | 1 |
| Novikov, DS | 1 |
| Davitz, MS | 1 |
| Inglese, M | 2 |
| Fieremans, E | 1 |
| Tian, R | 1 |
| Han, L | 1 |
| Hou, Z | 1 |
| Hao, S | 1 |
| Mao, X | 1 |
| Zhu, Z | 1 |
| Tao, X | 1 |
| Zhang, Q | 1 |
| Liu, B | 1 |
| Fonseca, R | 1 |
| Carvalho, RA | 1 |
| Lemos, C | 1 |
| Sequeira, AC | 1 |
| Pita, IR | 1 |
| Carvalho, F | 1 |
| Silva, CD | 1 |
| Prediger, RD | 1 |
| Jarak, I | 1 |
| Cunha, RA | 1 |
| Fontes Ribeiro, CA | 1 |
| Köfalvi, A | 1 |
| Pereira, FC | 1 |
| Hoch, SE | 1 |
| Tal, A | 2 |
| Immonen, RJ | 1 |
| Kharatishvili, I | 1 |
| Niskanen, JP | 1 |
| Gröhn, H | 1 |
| Pitkänen, A | 1 |
| Gröhn, OH | 1 |
| Pérez-Dueñas, B | 1 |
| De La Osa, A | 1 |
| Capdevila, A | 1 |
| Navarro-Sastre, A | 1 |
| Leist, A | 1 |
| Ribes, A | 1 |
| García-Cazorla, A | 1 |
| Serrano, M | 1 |
| Pineda, M | 1 |
| Campistol, J | 1 |
| Aygok, GA | 2 |
| Marmarou, A | 8 |
| Fatouros, P | 3 |
| Kettenmann, B | 1 |
| Bullock, RM | 3 |
| Scafidi, S | 1 |
| O'Brien, J | 1 |
| Hopkins, I | 1 |
| Robertson, C | 1 |
| Fiskum, G | 2 |
| McKenna, M | 1 |
| Nucci-da-Silva, MP | 1 |
| Amaro, E | 1 |
| Sarmento, E | 1 |
| Moreira, P | 1 |
| Brito, C | 1 |
| Souza, J | 1 |
| Jevoux, C | 1 |
| Bigal, M | 1 |
| D'Urso, S | 1 |
| Lescot, T | 1 |
| Fulla-Oller, L | 2 |
| Po, C | 1 |
| Chen, XR | 1 |
| Puybasset, L | 1 |
| Gillet, B | 1 |
| Plotkine, M | 1 |
| Meric, P | 1 |
| Marchand-Leroux, C | 1 |
| Arun, P | 1 |
| Ariyannur, PS | 1 |
| Moffett, JR | 1 |
| Xing, G | 1 |
| Hamilton, K | 1 |
| Grunberg, NE | 1 |
| Ives, JA | 1 |
| Namboodiri, AM | 1 |
| Ficek, K | 1 |
| Blamek, S | 1 |
| Syguła, D | 1 |
| Miszczyk, L | 1 |
| Sońta-Jakimczyk, D | 1 |
| Tarnawski, R | 1 |
| Babikian, T | 3 |
| Marion, SD | 1 |
| Copeland, S | 1 |
| Alger, JR | 1 |
| O'Neill, J | 1 |
| Cazalis, F | 1 |
| Mink, R | 1 |
| Giza, CC | 1 |
| Vu, JA | 1 |
| Hilleary, SM | 1 |
| Kernan, CL | 1 |
| Newman, N | 1 |
| Asarnow, RF | 1 |
| Zahr, NM | 1 |
| Mayer, D | 1 |
| Rohlfing, T | 1 |
| Hasak, MP | 1 |
| Hsu, O | 1 |
| Vinco, S | 1 |
| Orduna, J | 1 |
| Luong, R | 1 |
| Sullivan, EV | 1 |
| Pfefferbaum, A | 1 |
| Aaen, GS | 1 |
| Holshouser, BA | 7 |
| Sheridan, C | 1 |
| Colbert, C | 1 |
| McKenney, M | 1 |
| Kido, D | 2 |
| Ashwal, S | 7 |
| Govind, V | 1 |
| Gold, S | 1 |
| Kaliannan, K | 1 |
| Saigal, G | 1 |
| Falcone, S | 1 |
| Arheart, KL | 1 |
| Harris, L | 1 |
| Jagid, J | 1 |
| Maudsley, AA | 1 |
| Rao, V | 1 |
| Munro, CA | 1 |
| Rosenberg, P | 1 |
| Ward, J | 1 |
| Bertrand, M | 1 |
| Degoankar, M | 1 |
| Horská, A | 1 |
| Pham, D | 1 |
| Yousem, DM | 1 |
| Barker, PB | 2 |
| Capizzano, AA | 1 |
| Jorge, RE | 1 |
| Robinson, RG | 1 |
| Lin, K | 1 |
| Taylor, MJ | 1 |
| Heaton, R | 1 |
| Franklin, D | 1 |
| Jernigan, T | 1 |
| Fennema-Notestine, C | 1 |
| McCutchan, A | 1 |
| Atkinson, JH | 1 |
| Ellis, RJ | 1 |
| McArthur, J | 1 |
| Morgello, S | 1 |
| Simpson, D | 1 |
| Collier, AC | 1 |
| Marra, C | 1 |
| Gelman, B | 1 |
| Clifford, D | 1 |
| Grant, I | 1 |
| Deng-Bryant, Y | 1 |
| Prins, ML | 1 |
| Hovda, DA | 1 |
| Harris, NG | 1 |
| Prieto, R | 2 |
| Taya, K | 1 |
| Barrios, L | 2 |
| Pascual, JM | 2 |
| Marmarou, CR | 1 |
| Grimmelt, AC | 1 |
| Eitzen, S | 1 |
| Balakhadze, I | 1 |
| Fischer, B | 1 |
| Wölfer, J | 1 |
| Schiffbauer, H | 1 |
| Gorji, A | 1 |
| Greiner, C | 1 |
| Johnson, B | 1 |
| Zhang, K | 1 |
| Gay, M | 1 |
| Neuberger, T | 1 |
| Horovitz, S | 1 |
| Hallett, M | 1 |
| Sebastianelli, W | 1 |
| Slobounov, S | 1 |
| Li, H | 1 |
| Li, JP | 1 |
| Lin, CG | 1 |
| Liu, XW | 1 |
| Geng, ZJ | 1 |
| Mo, YX | 1 |
| Zhang, R | 1 |
| Xie, CM | 1 |
| Semenova, NA | 1 |
| Akhadov, TA | 1 |
| Petryaykin, AV | 1 |
| Sidorin, SS | 1 |
| Lukovenkov, AV | 1 |
| Varfolomeev, SD | 1 |
| Galloway, M | 1 |
| Ghoddoussi, F | 1 |
| Kepsel, A | 1 |
| VandeVord, P | 1 |
| Schuhmann, MU | 2 |
| Stiller, D | 2 |
| Skardelly, M | 2 |
| Thomas, S | 1 |
| Samii, M | 2 |
| Brinker, T | 2 |
| Hoyle, R | 1 |
| Beaumont, A | 1 |
| Sawauchi, S | 1 |
| Bullock, R | 4 |
| Young, H | 1 |
| Macmillan, CS | 1 |
| Wild, JM | 1 |
| Wardlaw, JM | 1 |
| Andrews, PJ | 1 |
| Marshall, I | 1 |
| Easton, VJ | 1 |
| Uzan, M | 1 |
| Albayram, S | 1 |
| Dashti, SG | 1 |
| Aydin, S | 1 |
| Hanci, M | 1 |
| Kuday, C | 1 |
| Gillessen, T | 1 |
| Budd, SL | 1 |
| Lipton, SA | 1 |
| Danielsen, ER | 2 |
| Christensen, PB | 1 |
| Arlien-Søborg, P | 1 |
| Thomsen, C | 1 |
| Bernarding, J | 1 |
| Klinge, PM | 1 |
| Samii, A | 1 |
| Dunbar, J | 1 |
| Parry, L | 1 |
| Shores, A | 1 |
| Rae, C | 1 |
| Kemp, A | 1 |
| Waugh, MC | 1 |
| Chaseling, R | 1 |
| Joy, P | 1 |
| Guo, YW | 1 |
| Xu, RX | 1 |
| Holshouser, B | 1 |
| Tong, K | 1 |
| Serna, T | 1 |
| Osterdock, R | 1 |
| Gross, M | 1 |
| Shutter, L | 2 |
| Tong, KA | 3 |
| Delfini, R | 2 |
| Cimatti, M | 3 |
| Hunter, JV | 1 |
| Thornton, RJ | 1 |
| Wang, ZJ | 1 |
| Levin, HS | 1 |
| Roberson, G | 1 |
| Brooks, WM | 4 |
| Swank, PR | 1 |
| Makoroff, KL | 1 |
| Cecil, KM | 5 |
| Care, M | 1 |
| Ball, WS | 1 |
| Payen, JF | 1 |
| Francony, G | 1 |
| Fauvage, B | 1 |
| Le Bas, JF | 1 |
| Choi, CB | 1 |
| Kim, HY | 1 |
| Han, DY | 1 |
| Kang, YW | 1 |
| Han, YM | 1 |
| Jeun, SS | 1 |
| Choe, BY | 1 |
| Donzelli, S | 1 |
| Abrahamson, EE | 1 |
| Ikonomovic, MD | 1 |
| Ciallella, JR | 1 |
| Hope, CE | 1 |
| Paljug, WR | 1 |
| Isanski, BA | 1 |
| Flood, DG | 1 |
| Clark, RS | 2 |
| DeKosky, ST | 2 |
| Sen, J | 1 |
| Petzold, A | 1 |
| Russo, S | 1 |
| Kitchen, N | 1 |
| Smith, M | 1 |
| Bellia, F | 1 |
| Zhong, C | 1 |
| Zhao, X | 1 |
| Van, KC | 1 |
| Bzdega, T | 1 |
| Smyth, A | 1 |
| Zhou, J | 1 |
| Kozikowski, AP | 1 |
| Jiang, J | 1 |
| O'Connor, WT | 1 |
| Berman, RF | 1 |
| Neale, JH | 1 |
| Lyeth, BG | 1 |
| Oyoyo, U | 1 |
| Ghamsary, M | 1 |
| Saunders, D | 1 |
| Yeo, RA | 3 |
| Jung, RE | 3 |
| Schuff, N | 1 |
| Meyerhoff, DJ | 1 |
| Mueller, S | 1 |
| Chao, L | 1 |
| Sacrey, DT | 1 |
| Laxer, K | 1 |
| Weiner, MW | 1 |
| Halbower, AC | 1 |
| Degaonkar, M | 1 |
| Earley, CJ | 1 |
| Marcus, CL | 1 |
| Smith, PL | 1 |
| Prahme, MC | 1 |
| Mahone, EM | 1 |
| Freier, MC | 2 |
| Riggs, ML | 1 |
| Burley, T | 1 |
| Phillips, JP | 1 |
| Brown, AJ | 1 |
| Campbell, RC | 1 |
| Gardner-Nichols, J | 1 |
| Nakabayashi, M | 1 |
| Suzaki, S | 1 |
| Tomita, H | 1 |
| Cohen, BA | 1 |
| Rusinek, H | 1 |
| Castillo, M | 1 |
| Solivera, J | 1 |
| López-Larrubia, P | 1 |
| Cerdán, S | 1 |
| Roda, JM | 1 |
| Kirov, I | 1 |
| Fleysher, L | 1 |
| Fatouros, PP | 1 |
| Portella, G | 1 |
| Casey, PA | 1 |
| McKenna, MC | 1 |
| Saraswati, M | 1 |
| Robertson, CL | 1 |
| Palmer, AM | 3 |
| Marion, DW | 4 |
| Botscheller, ML | 2 |
| Swedlow, PE | 1 |
| Styren, SD | 1 |
| Michaelis, T | 1 |
| Ross, BD | 1 |
| Redd, EE | 1 |
| Kuchiwaki, H | 1 |
| Inao, S | 1 |
| Yamamoto, M | 1 |
| Yoshida, K | 2 |
| Sugita, K | 1 |
| Hinshaw, DB | 2 |
| Schell, RM | 1 |
| Bailey, L | 1 |
| Luh, GY | 1 |
| Shu, S | 1 |
| Kahlon, S | 1 |
| Auld, KL | 1 |
| Tomasi, LG | 1 |
| Perkin, RM | 1 |
| Puka-Sundvall, M | 1 |
| Sandberg, M | 1 |
| Hagberg, H | 1 |
| Ricci, R | 1 |
| Barbarella, G | 1 |
| Musi, P | 1 |
| Boldrini, P | 1 |
| Trevisan, C | 1 |
| Basaglia, N | 1 |
| Rubin, Y | 1 |
| Cecil, K | 1 |
| Wehrli, S | 1 |
| McIntosh, TK | 6 |
| Lenkinski, RE | 5 |
| Smith, DH | 4 |
| Stoffel, M | 1 |
| Eriskat, J | 1 |
| Plesnila, M | 1 |
| Aggarwal, N | 1 |
| Baethmann, A | 1 |
| Rao, VL | 1 |
| Başkaya, MK | 1 |
| Doğan, A | 1 |
| Rothstein, JD | 1 |
| Dempsey, RJ | 1 |
| Meaney, DF | 2 |
| Hills, EC | 1 |
| Sandel, ME | 1 |
| Mannon, LJ | 1 |
| Sinson, GP | 1 |
| Bagley, LJ | 2 |
| Chen, XH | 1 |
| Gennarelli, TA | 1 |
| Koura, SS | 1 |
| Doppenberg, EM | 2 |
| Choi, S | 1 |
| Young, HF | 3 |
| Di Pierro, D | 1 |
| Fazzina, G | 1 |
| Caruso, I | 1 |
| Al-Samsam, RH | 1 |
| Alessandri, B | 2 |
| Garnett, MR | 3 |
| Blamire, AM | 3 |
| Rajagopalan, B | 3 |
| Styles, P | 3 |
| Cadoux-Hudson, TA | 3 |
| Stidley, CA | 1 |
| Petropoulos, H | 1 |
| Weers, DC | 1 |
| Friedman, SD | 1 |
| Barlow, MA | 1 |
| Sibbitt, WL | 1 |
| Corkill, RG | 2 |
| al-Samsam, R | 1 |
| Corwin, F | 1 |
| Ruppel, RA | 1 |
| Kochanek, PM | 2 |
| Adelson, PD | 1 |
| Rose, ME | 2 |
| Wisniewski, SR | 1 |
| Bell, MJ | 1 |
| Graham, SH | 2 |
| Sinson, G | 1 |
| Torchia, M | 1 |
| McGowan, JC | 1 |
| Manners, DN | 1 |
| Young, JD | 1 |
| Gasparovic, C | 1 |
| Arfai, N | 1 |
| Smid, N | 1 |
| Feeney, DM | 1 |
| Gopinath, SP | 1 |
| Valadka, AB | 1 |
| Goodman, JC | 1 |
| Robertson, CS | 1 |
| Khiat, A | 1 |
| Yared, Z | 1 |
| Bard, C | 1 |
| Lacroix, A | 1 |
| Boulanger, Y | 1 |
| Movsas, B | 1 |
| Li, BS | 1 |
| Fowble, BL | 1 |
| Nicolaou, N | 1 |
| Soukup, J | 1 |
| Zauner, A | 1 |
| Menzel, M | 1 |
| Gilman, C | 1 |
| Suzuki, M | 1 |
| Kudo, A | 1 |
| Sugawara, A | 1 |
| Kubo, Y | 1 |
| Suzuki, T | 1 |
| Ogasawara, K | 1 |
| Doi, M | 1 |
| Ogawa, A | 1 |
| Huerbin, MB | 1 |
| Melick, J | 1 |
| Schiding, JK | 1 |
| Olney, JW | 1 |
| Cohen, Y | 1 |
| Sanada, T | 1 |
| Pitts, LH | 1 |
| Chang, LH | 1 |
| Nishimura, MC | 1 |
| Weinstein, PR | 1 |
| Litt, L | 1 |
| James, TL | 1 |
| Faden, AI | 2 |
| Demediuk, P | 1 |
| Panter, SS | 1 |
| Vink, R | 2 |
| Simon, RP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077] | 70 participants (Anticipated) | Interventional | 2022-05-14 | Recruiting | |||
| Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.[NCT02049411] | Phase 2 | 80 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for aspartic acid and Brain Injuries
| Article | Year |
|---|---|
A systematic review of Magnetic Resonance Imaging and Spectroscopy in brain injury after drowning.
Topics: Aspartic Acid; Brain Injuries; Child; Child, Preschool; Drowning; Female; Humans; Hypoxia, Brain; In | 2009 |
Biochemical and neurochemical sequelae following mild traumatic brain injury: summary of experimental data and clinical implications.
Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Diffuse Axonal Injury; Disease Models, Animal; Humans | 2010 |
Excitatory amino acid neurotoxicity.
Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Calcium; Epilepsy; Glutamic Acid; Hum | 2002 |
[Contribution of magnetic resonance spectroscopy in predicting severity and outcome in traumatic brain injury].
Topics: Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Injuries; Choline; Craniocerebral Trauma; | 2005 |
NAA and higher cognitive function in humans.
Topics: Aspartic Acid; Brain; Brain Injuries; Cognition; Humans; Magnetic Resonance Spectroscopy | 2006 |
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; | 2006 |
Susceptibility-weighted imaging and proton magnetic resonance spectroscopy in assessment of outcome after pediatric traumatic brain injury.
Topics: Aspartic Acid; Axons; Brain Injuries; Child; Choline; Creatine; Humans; Imaging, Three-Dimensional; | 2006 |
Whole-brain N-acetylaspartate: a marker of the severity of mild head trauma.
Topics: Aspartic Acid; Biomarkers; Brain Injuries; Humans; Magnetic Resonance Spectroscopy; Trauma Severity | 2007 |
Excitotoxin-mediated neuron death in youth and old age.
Topics: Aging; Alzheimer Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases, Metabolic; Brain Inju | 1990 |
Role of endogenous excitatory amino acid neurotransmitters in the pathogenesis and evolution of acute brain injury.
Topics: Acute Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Injuries; Calcium; Calcium | 1989 |
5 trials available for aspartic acid and Brain Injuries
| Article | Year |
|---|---|
An experimental study on acute brain radiation injury: dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology.
Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Magnetic Resonance Spectroscopy; Protons; Rabbits; | 2012 |
Proton MR spectroscopy and MRI-volumetry in mild traumatic brain injury.
Topics: Adult; Age Factors; Aspartic Acid; Atrophy; Axons; Brain; Brain Injuries; Female; Glasgow Coma Scale | 2007 |
Assessment of mitochondrial impairment in traumatic brain injury using high-resolution proton magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Follow-Up Studies; Huma | 2008 |
Evidence for cellular damage in normal-appearing white matter correlates with injury severity in patients following traumatic brain injury: A magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aged; Amnesia; Aspartic Acid; Axons; Brain Chemistry; Brain Injuries; Cerebral Co | 2000 |
Early proton magnetic resonance spectroscopy in normal-appearing brain correlates with outcome in patients following traumatic brain injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Choline; Creatine; Disabili | 2000 |
102 other studies available for aspartic acid and Brain Injuries
| Article | Year |
|---|---|
Replicability of proton MR spectroscopic imaging findings in mild traumatic brain injury: Implications for clinical applications.
Topics: Adult; Aspartic Acid; Brain; Brain Concussion; Brain Injuries; Choline; Creatine; Female; Humans; Ma | 2023 |
Hemodialysis-Related Acute Brain Injury Demonstrated by Application of Intradialytic Magnetic Resonance Imaging and Spectroscopy.
Topics: Aged; Aspartic Acid; Brain; Brain Injuries; Choline; Diffusion Tensor Imaging; Female; Humans; Magne | 2023 |
[Effect of aqueous extract of Corni Fructus on Aβ_(25-35)-induced brain injury and neuroinflammation in mice with Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aspartic Acid; Brain Injuries; Cornus; Cysteine; | 2023 |
Wu-zhu-yu Decoction reduces early brain injury following subarachnoid hemorrhage in vivo and in vitro by activating the Nrf2 antioxidant system via SIRT6 targeting.
Topics: Animals; Antioxidants; Apoptosis; Aspartic Acid; Brain Injuries; Caspase 3; Hemoglobins; Neuroprotec | 2024 |
Hippocampal changes in inflammasomes, apoptosis, and MEMRI after radiation-induced brain injury in juvenile rats.
Topics: Animals; Apoptosis; Aspartic Acid; Brain Injuries; Caspases; Creatine; Hippocampus; Inflammasomes; M | 2020 |
Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury.
Topics: Aspartic Acid; Brain; Brain Injuries; Cerebellum; Choline; Creatine; Female; Gestational Age; Gray M | 2019 |
Metabolic changes in patients with aneurysmal subarachnoid hemorrhage apart from perfusion deficits: neuronal mitochondrial injury?
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Cerebrovascular Di | 2013 |
Impact of methamphetamine on regional metabolism and cerebral blood flow after traumatic brain injury.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Brain Injuries; Central Nerv | 2013 |
MRSI of the medial temporal lobe at 7 T in explosive blast mild traumatic brain injury.
Topics: Adult; Aspartic Acid; Biomarkers; Blast Injuries; Brain Injuries; Choline; Creatine; Explosions; Fem | 2014 |
Clinical correlations of proton magnetic resonance spectroscopy findings in acute phase after mild traumatic brain injury.
Topics: Adult; Aspartic Acid; Biomarkers; Brain Injuries; Cognition Disorders; Creatine; Female; Frontal Lob | 2014 |
Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury.
Topics: Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Caudate Nucleus; Choline; Corpus Striatu | 2014 |
The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury.
Topics: Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Amidohydrolases; Animals; Asparti | 2014 |
Magnetic resonance spectroscopic imaging of brain injury after nasopharyngeal cancer radiation in early delayed reaction.
Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; | 2014 |
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes.
Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyr | 2014 |
Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions.
Topics: Analysis of Variance; Animals; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Injuries; Ce | 2015 |
N-acetyl-aspartate levels correlate with intra-axonal compartment parameters from diffusion MRI.
Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Choline; Creatine; Diffusion Magnetic Resonance | 2015 |
Neuroprotective efficacy of decompressive craniectomy after controlled cortical impact injury in rats: An MRI study.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Choline; Creatine; Decompressive Craniec | 2015 |
Methamphetamine Induces Anhedonic-Like Behavior and Impairs Frontal Cortical Energetics in Mice.
Topics: Anhedonia; Animals; Aspartic Acid; Brain Injuries; Central Nervous System Stimulants; Cerebral Corte | 2017 |
When are metabolic ratios superior to absolute quantification? A statistical analysis.
Topics: Adult; Algorithms; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Data Interpretation, S | 2017 |
Distinct MRI pattern in lesional and perilesional area after traumatic brain injury in rat--11 months follow-up.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffusion Magnetic Resonan | 2009 |
Brain injury in glutaric aciduria type I: the value of functional techniques in magnetic resonance imaging.
Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain; Brain Injuries; Brain Mapping; Creatine; | 2009 |
Assessment of mitochondrial impairment and cerebral blood flow in severe brain injured patients.
Topics: Aspartic Acid; Blood Flow Velocity; Brain Injuries; Cerebrovascular Circulation; Diffusion Magnetic | 2008 |
Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Edema; Brain Injuries; Glucose; Glutamic Acid; Glutamine; | 2009 |
Proton spectroscopy in patients with post-traumatic headache attributed to mild head injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Brain Ma | 2009 |
Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain Chemistry; Brain Injuries; Creatine; Energy Me | 2010 |
Temporal and regional changes after focal traumatic brain injury.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Brain Mapping; Cerebral Cortex; Choline; | 2010 |
Metabolic acetate therapy for the treatment of traumatic brain injury.
Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Aspartic Acid; Brain; Brain Injuries; Disease Mod | 2010 |
Evaluation of the late effects of CNS prophylactic treatment in childhood acute lymphoblastic leukemia (ALL) using magnetic resonance spectroscopy.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Child, Preschool; Choline; C | 2010 |
Metabolic levels in the corpus callosum and their structural and behavioral correlates after moderate to severe pediatric TBI.
Topics: Adolescent; Age Factors; Aging; Anisotropy; Aspartic Acid; Axons; Biomarkers; Brain Injuries; Child; | 2010 |
Brain injury and recovery following binge ethanol: evidence from in vivo magnetic resonance spectroscopy.
Topics: Alcoholism; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain Injuries; Brain Mapping | 2010 |
Magnetic resonance spectroscopy predicts outcomes for children with nonaccidental trauma.
Topics: Aspartic Acid; Brain Injuries; Cerebral Infarction; Child; Child, Preschool; Female; Glasgow Coma Sc | 2010 |
Whole-brain proton MR spectroscopic imaging of mild-to-moderate traumatic brain injury and correlation with neuropsychological deficits.
Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cognition Disorders; C | 2010 |
Neuroanatomical correlates of depression in post traumatic brain injury: preliminary results of a pilot study.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Brain Injuries; Case-Control Studies; Choline; Cognition | 2010 |
Limbic metabolic abnormalities in remote traumatic brain injury and correlation with psychiatric morbidity and social functioning.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Brain Mapping; Ca | 2010 |
Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals.
Topics: Adult; Aspartic Acid; Brain Injuries; Cognition Disorders; Depression; Executive Function; Female; H | 2011 |
Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury.
Topics: 3-Hydroxybutyric Acid; Age Factors; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Diet | 2011 |
Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate.
Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Blood Gas Analysis; Blood Pressure; B | 2011 |
Closed traumatic brain injury model in sheep mimicking high-velocity, closed head trauma in humans.
Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Carbon Dioxide; Disease Models, Animal; Electron Spin | 2011 |
Metabolic alterations in corpus callosum may compromise brain functional connectivity in MTBI patients: an 1H-MRS study.
Topics: Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Corpus Callosum; Creatine; Female; Hip | 2012 |
Metabolic dysfunction and relationship in human frontoparietal cortex in severe traumatic brain injury: single-voxel (1)H magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Child; Child, Preschool; Choline; | 2012 |
Diffuse axonal injury in mild traumatic brain injury: a 3D multivoxel proton MR spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Brain Mapping; Choline; Creatine; Diffuse Axonal I | 2013 |
Effects of blast-induced neurotrauma on the nucleus accumbens.
Topics: Animals; Apoptosis; Aspartic Acid; bcl-2-Associated X Protein; Blast Injuries; Brain Injuries; Caspa | 2013 |
Long-time in-vivo metabolic monitoring following experimental brain contusion using proton magnetic resonance spectroscopy.
Topics: Animals; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Brain Injuries; Disease Models, Animal; Fu | 2002 |
Application of chemical shift imaging for measurement of NAA in head injured patients.
Topics: Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatinine; Humans; Magnetic Resonance Imaging; | 2002 |
Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Child; Choline; Creatine; C | 2002 |
Thalamic proton magnetic resonance spectroscopy in vegetative state induced by traumatic brain injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Child; Choline; Creatine; Diffuse Axonal Inj | 2003 |
Axonal recovery after severe traumatic brain injury demonstrated in vivo by 1H MR spectroscopy.
Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Cognition; Female; Humans; Magnetic Resonance Sp | 2003 |
Metabolic changes in the vicinity of brain contusions: a proton magnetic resonance spectroscopy and histology study.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatine; Functional Laterality; Glutam | 2003 |
The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury.
Topics: Animals; Aspartic Acid; Brain Injuries; Cyclosporine; Drug Administration Schedule; Infusions, Intra | 2004 |
An investigation of neuronal integrity in severe paediatric traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Child; Choline; Cognition Disorders; Creatin | 2004 |
[Detection of amino acid neurotransmitters in cerebrospinal fluid of patients in persistent vegetative state].
Topics: Adolescent; Adult; Alanine; Aspartic Acid; Brain Injuries; Child; Female; Glutamic Acid; Glycine; Hu | 2005 |
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Com | 2004 |
Proton MRS in acute traumatic brain injury: role for glutamate/glutamine and choline for outcome prediction.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Cerebral Cortex; Choline; Creatinine; Evoked | 2004 |
Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats.
Topics: Animals; Ascorbic Acid; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Chromatog | 2005 |
Late proton MR spectroscopy in children after traumatic brain injury: correlation with cognitive outcomes.
Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; C | 2005 |
Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury.
Topics: Aspartic Acid; Brain Chemistry; Brain Injuries; Critical Care; Female; Fractures, Bone; Frontal Lobe | 2005 |
In vivo 1H MR spectroscopic findings in traumatic contusion of ICR mouse brain induced by fluid percussion injury.
Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Creatine; Magnetic Resonance Spectroscopy; Male; Mi | 2005 |
Hypothesis of the postconcussive vulnerable brain: experimental evidence of its metabolic occurrence.
Topics: Adenosine Triphosphate; Animals; Apyrase; Aspartic Acid; Blood Gas Analysis; Brain; Brain Injuries; | 2005 |
Caspase inhibition therapy abolishes brain trauma-induced increases in Abeta peptide: implications for clinical outcome.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Blotting, Western; Br | 2006 |
Extracellular N-acetylaspartate depletion in traumatic brain injury.
Topics: Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Extracellular Space; Humans; Magnetic R | 2006 |
NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat.
Topics: Animals; Aspartic Acid; Brain Injuries; Cytoprotection; Dipeptides; Disease Models, Animal; Down-Reg | 2006 |
Prospective longitudinal proton magnetic resonance spectroscopic imaging in adult traumatic brain injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Case-Control Studies; Corpus Callosum; Femal | 2006 |
Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Cerebral Cortex; Child; Choline; Cr | 2006 |
MR spectroscopy: predicting long-term neuropsychological outcome following pediatric TBI.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Child; Child, Preschool; Creatine; Female; Glutamic Acid; | 2006 |
Magnetic resonance spectroscopy detects brain injury and predicts cognitive functioning in children with brain injuries.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; Creatine | 2006 |
Assessment of metabolic cerebral damage using proton magnetic resonance spectroscopy in mild traumatic brain injury.
Topics: Adult; Aspartic Acid; Boxing; Brain; Brain Injuries; Humans; Magnetic Resonance Spectroscopy; Male | 2006 |
Neural injury and recovery near cortical contusions: a clinical magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Creatine; Female; G | 2007 |
Time course of early metabolic changes following diffuse traumatic brain injury in rats as detected by (1)H NMR spectroscopy.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffuse Axona | 2007 |
Characterizing 'mild' in traumatic brain injury with proton MR spectroscopy in the thalamus: Initial findings.
Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Magneti | 2007 |
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.
Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; C | 2008 |
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain | 1993 |
Three methods of calibration in quantitative proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Body Water; Brain; Brain Chemistry; Brain Injuries; Calibration; Choline; Crea | 1995 |
Therapeutic hypothermia is cytoprotective without attenuating the traumatic brain injury-induced elevations in interstitial concentrations of aspartate and glutamate.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Chromatography, High Pressure Liquid; Gl | 1993 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats | 1994 |
Proton magnetic resonance spectroscopy in the evaluation of children with congenital heart disease and acute central nervous system injury.
Topics: Aspartic Acid; Brain; Brain Injuries; Cardiopulmonary Bypass; Case-Control Studies; Child, Preschool | 1996 |
Proton MR spectroscopy after acute central nervous system injury: outcome prediction in neonates, infants, and children.
Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Brain Injuries; Child; Choline; Discriminant Analy | 1997 |
Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine.
Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Carotid Arter | 1997 |
Localised proton MR spectroscopy of brain metabolism changes in vegetative patients.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Cre | 1997 |
High-resolution 1H NMR spectroscopy following experimental brain trauma.
Topics: Animals; Aspartic Acid; Brain Injuries; Disease Models, Animal; Magnetic Resonance Spectroscopy; Mal | 1997 |
The penumbra zone of a traumatic cortical lesion: a microdialysis study of excitatory amino acid release.
Topics: Animals; Aspartic Acid; Brain Injuries; Excitatory Amino Acids; Glutamic Acid; Male; Microdialysis; | 1997 |
Traumatic brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain; | 1998 |
High-field proton magnetic resonance spectroscopy of a swine model for axonal injury.
Topics: Animals; Aspartic Acid; Axons; Brain; Brain Injuries; Creatine; Disease Models, Animal; Female; Magn | 1998 |
Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients.
Topics: Acceleration; Accidents, Traffic; Adult; Aged; Aspartic Acid; Axons; Brain Concussion; Brain Disease | 1998 |
Magnetic resonance spectroscopy of diffuse brain trauma in the pig.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Axons; Behavior, Animal; Brain Chemistry; Brain Inju | 1998 |
Relationship between excitatory amino acid release and outcome after severe human head injury.
Topics: Animals; Aspartic Acid; Brain Damage, Chronic; Brain Injuries; Cerebral Cortex; Excitatory Amino Aci | 1998 |
Ion-pairing high-performance liquid chromatographic method for the detection of N-acetylaspartate and N-acetylglutamate in cerebral tissue extracts.
Topics: Animals; Aspartic Acid; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Gluta | 2000 |
Extracellular N-acetyl-aspartate as a biochemical marker of the severity of neuronal damage following experimental acute traumatic brain injury.
Topics: Animals; Aspartic Acid; Biomarkers; Blood Gas Analysis; Blood Pressure; Brain; Brain Chemistry; Brai | 2000 |
Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Choline; Cognition Disorders; Creatinine; Cr | 2000 |
Acute and late changes in N-acetyl-aspartate following diffuse axonal injury in rats: an MRI spectroscopy and microdialysis study.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Diffuse Axonal Injury; Magnetic Resonance Imagin | 2000 |
Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Brain Ischemia; Case-Control Studies; Cerebr | 2001 |
Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury.
Topics: Aspartic Acid; Axons; Biomarkers; Brain; Brain Injuries; Brain Stem; Corpus Callosum; Creatine; Glas | 2001 |
Altered cellular metabolism following traumatic brain injury: a magnetic resonance spectroscopy study.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Choline; Creatine; | 2001 |
Decrease and recovery of N-acetylaspartate/creatine in rat brain remote from focal injury.
Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Creatine; Magnetic Resonance Spectroscopy; Occipital | 2001 |
Extracellular glutamate and aspartate in head injured patients.
Topics: Adolescent; Adult; Aspartic Acid; Brain Edema; Brain Injuries; Extracellular Space; Female; Glasgow | 2000 |
Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Injuries; Cell Membrane; Choline; Crea | 2001 |
Quantifying radiation therapy-induced brain injury with whole-brain proton MR spectroscopy: initial observations.
Topics: Adult; Aged; Aspartic Acid; Brain Injuries; Female; Humans; Magnetic Resonance Spectroscopy; Male; M | 2001 |
Relationship between brain temperature, brain chemistry and oxygen delivery after severe human head injury: the effect of mild hypothermia.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Body Temperature; Brain; Brain Chemistry; Brain Injuries; Ca | 2002 |
Amino acid concentrations in the blood of the jugular vein and peripheral artery after traumatic brain injury: decreased release of glutamate into the jugular vein in the early phase.
Topics: Adolescent; Adult; Aged; Amino Acids; Arteries; Aspartic Acid; Brain Injuries; Cystine; Female; gamm | 2002 |
Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury.
Topics: Animals; Aspartic Acid; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Ac | 2002 |
Surface coil spectroscopic imaging: time and spatial evolution of lactate production following fluid percussion brain injury.
Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Brain Injuries; Deuterium; Fourier Analysis; | 1991 |
The role of excitatory amino acids and NMDA receptors in traumatic brain injury.
Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Injuries; Dextrorphan; Glutamates; Glutam | 1989 |
Nonedited 1H NMR lactate/n-acetyl aspartate ratios and the in vivo determination of lactate concentration in brain.
Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Lactates; Magnetic Resonance Spectroscopy; Rats; Rats | 1988 |