aspartic acid has been researched along with Brain Edema in 54 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bumetanide treatment increased ATP/Pi and PCr/Pi and ameliorated the declines in these values with insulin/saline treatment." | 5.36 | Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide. ( Anderson, SE; Glaser, N; O'Donnell, ME; Tancredi, DJ; Yuen, N, 2010) |
| "Brain alterations such as hepatic encephalopathy or brain edema are usually associated with liver failure." | 2.50 | Magnetic resonance of the brain in chronic and acute liver failure. ( Chavarria, L; Cordoba, J, 2014) |
| "Brain edema was maximal on MR imaging 3 h after poisoning." | 1.42 | Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model. ( Cohen, Y; Eisenkraft, A; Kadar, T; Kassirer, M; Milk, N; Rosman, Y; Shiyovich, A; Shrot, S; Tauber, M, 2015) |
| "Bumetanide treatment increased ATP/Pi and PCr/Pi and ameliorated the declines in these values with insulin/saline treatment." | 1.36 | Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide. ( Anderson, SE; Glaser, N; O'Donnell, ME; Tancredi, DJ; Yuen, N, 2010) |
| "Subclinical cerebral edema occurs in many, if not most, children with diabetic ketoacidosis (DKA) and may be an indicator of subtle brain injury." | 1.34 | Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis. ( Barnes, PD; Buonocore, MH; DiCarlo, J; Glaser, NS; Kuppermann, N; Marcin, JP; McCarthy, T; Neely, EK; Wootton-Gorges, SL, 2007) |
| "PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy." | 1.33 | Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006) |
| "Choline peak area was increased in tumor, creatine and N-acetyl aspartate were decreased in edema and tumor compared with unaffected brain tissue." | 1.31 | 1H chemical shift imaging characterization of human brain tumor and edema. ( Oudkerk, M; Sijens, PE, 2002) |
| "Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus." | 1.30 | Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999) |
| " There was no abnormal locomotor activity in the L-CPA rats treated with MK-801 except for the first 4 hr following dosing when animals were severely sedated." | 1.29 | L-2-chloropropionic acid-induced neurotoxicity is prevented by MK-801: possible role of NMDA receptors in the neuropathology. ( Gyte, A; Lock, EA; Simpson, MG; Widdowson, PS; Wyatt, I, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (9.26) | 18.7374 |
| 1990's | 20 (37.04) | 18.2507 |
| 2000's | 17 (31.48) | 29.6817 |
| 2010's | 12 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, W | 1 |
| Xu, S | 1 |
| Wang, J | 1 |
| Zhang, K | 1 |
| Zhang, M | 1 |
| Cao, Y | 1 |
| Ren, H | 1 |
| Zheng, D | 1 |
| Zhong, C | 1 |
| Chavarria, L | 1 |
| Cordoba, J | 1 |
| Parra, NA | 1 |
| Maudsley, AA | 1 |
| Gupta, RK | 2 |
| Ishkanian, F | 1 |
| Huang, K | 1 |
| Walker, GR | 1 |
| Padgett, K | 1 |
| Roy, B | 1 |
| Panoff, J | 1 |
| Markoe, A | 1 |
| Stoyanova, R | 1 |
| Shrot, S | 1 |
| Tauber, M | 1 |
| Shiyovich, A | 1 |
| Milk, N | 1 |
| Rosman, Y | 1 |
| Eisenkraft, A | 1 |
| Kadar, T | 1 |
| Kassirer, M | 1 |
| Cohen, Y | 2 |
| Tian, R | 1 |
| Han, L | 1 |
| Hou, Z | 1 |
| Hao, S | 1 |
| Mao, X | 1 |
| Zhu, Z | 1 |
| Tao, X | 1 |
| Zhang, Q | 1 |
| Liu, B | 1 |
| Yoon, KJ | 1 |
| Lee, YT | 1 |
| Chae, SW | 1 |
| Park, CR | 1 |
| Kim, DY | 1 |
| Schubert, GA | 1 |
| Poli, S | 1 |
| Schilling, L | 1 |
| Heiland, S | 1 |
| Thomé, C | 1 |
| Scafidi, S | 1 |
| O'Brien, J | 1 |
| Hopkins, I | 1 |
| Robertson, C | 1 |
| Fiskum, G | 1 |
| McKenna, M | 1 |
| Chernov, MF | 2 |
| Nakaya, K | 1 |
| Kasuya, H | 1 |
| Kato, K | 1 |
| Ono, Y | 2 |
| Yoshida, S | 1 |
| Nakamura, R | 1 |
| Suzuki, T | 1 |
| Muragaki, Y | 1 |
| Iseki, H | 1 |
| Kubo, O | 2 |
| Hori, T | 2 |
| Takakura, K | 2 |
| Lescot, T | 1 |
| Fulla-Oller, L | 2 |
| Po, C | 1 |
| Chen, XR | 1 |
| Puybasset, L | 1 |
| Gillet, B | 1 |
| Plotkine, M | 1 |
| Meric, P | 1 |
| Marchand-Leroux, C | 1 |
| Wootton-Gorges, SL | 2 |
| Buonocore, MH | 2 |
| Caltagirone, RA | 1 |
| Kuppermann, N | 2 |
| Glaser, NS | 2 |
| Glaser, N | 2 |
| Yuen, N | 2 |
| Anderson, SE | 1 |
| Tancredi, DJ | 1 |
| O'Donnell, ME | 1 |
| Signoretti, S | 2 |
| Lazzarino, G | 1 |
| Tavazzi, B | 2 |
| Vagnozzi, R | 2 |
| Ngo, C | 1 |
| Anderson, S | 1 |
| Trifu, A | 1 |
| O'Donnell, M | 1 |
| Righi, V | 1 |
| Tugnoli, V | 1 |
| Mucci, A | 1 |
| Bacci, A | 1 |
| Bonora, S | 1 |
| Schenetti, L | 1 |
| Sijens, PE | 1 |
| Oudkerk, M | 1 |
| Hayashi, M | 1 |
| Izawa, M | 1 |
| Maruyama, T | 1 |
| Usukura, M | 1 |
| Briellmann, RS | 1 |
| Wellard, RM | 1 |
| Jackson, GD | 1 |
| Boichot, C | 1 |
| Walker, PM | 1 |
| Durand, C | 1 |
| Grimaldi, M | 1 |
| Chapuis, S | 1 |
| Gouyon, JB | 1 |
| Brunotte, F | 1 |
| Huisman, TA | 1 |
| Klein, A | 1 |
| Werner, B | 1 |
| Straube, T | 1 |
| Boltshauser, E | 1 |
| Marcin, JP | 1 |
| Barnes, PD | 1 |
| Neely, EK | 1 |
| DiCarlo, J | 1 |
| McCarthy, T | 1 |
| Kamada, K | 2 |
| Houkin, K | 2 |
| Iwasaki, Y | 2 |
| Abe, H | 2 |
| Kashiwaba, T | 1 |
| Go, KG | 1 |
| Kamman, RL | 1 |
| Mooyaart, EL | 1 |
| Heesters, MA | 1 |
| Pruim, J | 1 |
| Vaalburg, W | 1 |
| Paans, AM | 1 |
| Kimelberg, HK | 1 |
| Rutledge, E | 1 |
| Goderie, S | 1 |
| Charniga, C | 1 |
| Green, AR | 1 |
| Cross, AJ | 1 |
| Gyngell, ML | 1 |
| Els, T | 1 |
| Hoehn-Berlage, M | 1 |
| Hossmann, KA | 1 |
| Kuchiwaki, H | 1 |
| Inao, S | 1 |
| Yamamoto, M | 1 |
| Yoshida, K | 1 |
| Sugita, K | 1 |
| Hida, K | 1 |
| Matsuzawa, H | 1 |
| Nakada, T | 1 |
| Widdowson, PS | 1 |
| Wyatt, I | 1 |
| Gyte, A | 1 |
| Simpson, MG | 1 |
| Lock, EA | 1 |
| Tan, WK | 1 |
| Williams, CE | 1 |
| During, MJ | 2 |
| Mallard, CE | 1 |
| Gunning, MI | 1 |
| Gunn, AJ | 1 |
| Gluckman, PD | 1 |
| Kimura, H | 1 |
| Grossman, RI | 1 |
| Lenkinski, RE | 1 |
| Gonzalez-Scarano, F | 1 |
| Fujikawa, DG | 1 |
| Kim, JS | 1 |
| Daniels, AH | 1 |
| Alcaraz, AF | 1 |
| Sohn, TB | 1 |
| Chumas, P | 1 |
| Condon, B | 1 |
| Oluoch-Olunya, D | 1 |
| Griffiths, S | 1 |
| Hadley, D | 1 |
| Teasdale, G | 1 |
| Sengar, AR | 1 |
| Dhanuka, AK | 1 |
| Roy, R | 1 |
| Das, K | 1 |
| Wardlaw, JM | 1 |
| Marshall, I | 1 |
| Wild, J | 1 |
| Dennis, MS | 1 |
| Cannon, J | 1 |
| Lewis, SC | 1 |
| Baunach, S | 1 |
| Meixensberger, J | 1 |
| Gerlach, M | 1 |
| Lan, J | 1 |
| Roosen, K | 1 |
| Estevez, AY | 1 |
| O'Regan, MH | 1 |
| Song, D | 1 |
| Phillis, JW | 1 |
| Stover, JF | 1 |
| Kempski, OS | 1 |
| Ashwal, S | 1 |
| Holshouser, BA | 1 |
| Shu, SK | 1 |
| Simmons, PL | 1 |
| Perkin, RM | 1 |
| Tomasi, LG | 1 |
| Knierim, DS | 1 |
| Sheridan, C | 1 |
| Craig, K | 1 |
| Andrews, GH | 1 |
| Hinshaw, DB | 1 |
| Demougeot, C | 1 |
| Garnier, P | 1 |
| Mossiat, C | 1 |
| Bertrand, N | 1 |
| Giroud, M | 1 |
| Beley, A | 1 |
| Marie, C | 1 |
| Horská, A | 1 |
| Ulug, AM | 1 |
| Melhem, ER | 1 |
| Filippi, CG | 1 |
| Burger, PC | 1 |
| Edgar, MA | 1 |
| Souweidane, MM | 1 |
| Carson, BS | 1 |
| Barker, PB | 1 |
| Son, BC | 1 |
| Park, CK | 1 |
| Choi, BG | 1 |
| Kim, EN | 1 |
| Choe, BY | 1 |
| Lee, KS | 1 |
| Kim, MC | 1 |
| Kang, JK | 1 |
| Schuhmann, MU | 1 |
| Stiller, D | 1 |
| Thomas, S | 1 |
| Brinker, T | 1 |
| Samii, M | 1 |
| Fatouros, PP | 1 |
| Heath, DL | 1 |
| Beaumont, A | 1 |
| Corwin, FD | 1 |
| al-Samsam, RH | 1 |
| Alessandri, B | 1 |
| Lazzarino, P | 1 |
| Bullock, R | 1 |
| Marmarou, A | 1 |
| Gopinath, SP | 1 |
| Valadka, AB | 1 |
| Goodman, JC | 1 |
| Robertson, CS | 1 |
| Leone, P | 1 |
| Janson, CG | 1 |
| McPhee, SJ | 1 |
| Freeman, JL | 1 |
| Coleman, LT | 1 |
| Smith, LJ | 1 |
| Shield, LK | 1 |
| Coraim, FI | 1 |
| Owen, A | 1 |
| Trubel, W | 1 |
| Kassal, H | 1 |
| Widhalm, K | 1 |
| Sanada, T | 1 |
| Pitts, LH | 1 |
| Chang, LH | 1 |
| Nishimura, MC | 1 |
| Weinstein, PR | 1 |
| Litt, L | 1 |
| James, TL | 1 |
| Steinberg, GK | 1 |
| Saleh, J | 1 |
| DeLaPaz, R | 1 |
| Kunis, D | 1 |
| Zarnegar, SR | 1 |
| Ellrén, K | 1 |
| Lehmann, A | 1 |
| Simon, RP | 1 |
| Young, RS | 1 |
| Stout, S | 1 |
| Cheng, J | 1 |
| Buniatian, HCh | 1 |
| Dallakian, BCh | 1 |
| Paul, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults[NCT03520569] | Early Phase 1 | 15 participants (Actual) | Interventional | 2019-02-04 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The augmentation index (AIx) measured at the radial artery is a measure of systemic arterial stiffness, and is defined as the ratio of augmentation (Δ P) to central pulse pressure and expressed as percent. AIx = (ΔP/PP) x 100, where P = pressure and PP = Pulse Pressure. Higher percentages indicate increased arterial stiffness. (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp
| Intervention | percentage (Mean) |
|---|---|
| Octreotide- Euglycemia | -4.15 |
| Octreotide - Euglycemia- Insulin Clamp | -2.23 |
| Octreotide- Hyperglycemia | -4.80 |
| Octreotide- Hyperglycemia - Insulin Clamp | -8.45 |
Flow mediated dilation measures the change in brachial diameter in response to 5 minutes of ischemia using B-mode ultrasound. It provides an index of nitric oxide generation by the endothelium . (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp
| Intervention | % change (Mean) |
|---|---|
| Octreotide- Euglycemia | 11.8 |
| Octreotide - Euglycemia- Insulin Clamp | 11.8 |
| Octreotide- Hyperglycemia | 8.9 |
| Octreotide- Hyperglycemia - Insulin Clamp | 8.95 |
The time required for a blood pressure wave to travel from the carotid to the femoral artery was measured in meter/sec. This is a measurement of central artery stiffness. Higher numbers indicate stiffer vessels (NCT03520569)
Timeframe: baseline and after 2 hour insulin clamp
| Intervention | m/sec (Mean) |
|---|---|
| Octreotide- Euglycemia | 5.21 |
| Octreotide - Euglycemia- Insulin Clamp | 5.06 |
| Octreotide- Hyperglycemia | 4.79 |
| Octreotide- Hyperglycemia - Insulin Clamp | 5.07 |
4 reviews available for aspartic acid and Brain Edema
| Article | Year |
|---|---|
Magnetic resonance of the brain in chronic and acute liver failure.
Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Edema; Choline; Creatine; Glutamic Acid; Gl | 2014 |
The pathophysiology of concussion.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Biomarkers; Brain; Brain Concussion; Brain Edema; En | 2011 |
Seizure-associated abnormalities in epilepsy: evidence from MR imaging.
Topics: Adult; Aspartic Acid; Atrophy; Brain; Brain Diseases; Brain Edema; Choline; Creatine; Diffusion Magn | 2005 |
Global CNS gene transfer for a childhood neurogenetic enzyme deficiency: Canavan disease.
Topics: Acetates; Acetazolamide; Amidohydrolases; Animals; Aspartic Acid; Brain; Brain Edema; Calcium Compou | 1999 |
50 other studies available for aspartic acid and Brain Edema
| Article | Year |
|---|---|
Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries, Traumatic; Disease Models, Animal; Gluta | 2018 |
Volumetric spectroscopic imaging of glioblastoma multiforme radiation treatment volumes.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Brain Mapping; Brain Neoplasms; Choline; Creatine; F | 2014 |
Early brain magnetic resonance imaging can predict short and long-term outcomes after organophosphate poisoning in a rat model.
Topics: Animals; Aspartic Acid; Atropine; Behavior, Animal; Brain; Brain Edema; Choline; Cholinesterase Reac | 2015 |
Neuroprotective efficacy of decompressive craniectomy after controlled cortical impact injury in rats: An MRI study.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Choline; Creatine; Decompressive Craniec | 2015 |
Effects of anodal transcranial direct current stimulation (tDCS) on behavioral and spatial memory during the early stage of traumatic brain injury in the rats.
Topics: Analysis of Variance; Animals; Aspartic Acid; Brain Edema; Brain Injuries, Traumatic; Brain-Derived | 2016 |
Hypothermia reduces cytotoxic edema and metabolic alterations during the acute phase of massive SAH: a diffusion-weighted imaging and spectroscopy study in rats.
Topics: Acute Disease; Animals; Aspartic Acid; Body Temperature; Brain; Brain Edema; Cerebral Cortex; Creati | 2008 |
Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Edema; Brain Injuries; Glucose; Glutamic Acid; Glutamine; | 2009 |
Metabolic alterations in the peritumoral brain in cases of meningiomas: 1H-MRS study.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Choline; Female; Humans; Lactic Acid; Lipids; Magnet | 2009 |
Temporal and regional changes after focal traumatic brain injury.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Brain Mapping; Cerebral Cortex; Choline; | 2010 |
Progressive decrease in N-acetylaspartate/Creatine ratio in a teenager with type 1 diabetes and repeated episodes of ketoacidosis without clinically apparent cerebral edema: Evidence for permanent brain injury.
Topics: Adolescent; Aspartic Acid; Basal Ganglia; Blood Glucose; Brain; Brain Damage, Chronic; Brain Edema; | 2010 |
Cerebral metabolic alterations in rats with diabetic ketoacidosis: effects of treatment with insulin and intravenous fluids and effects of bumetanide.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Bumetanide; Cerebrovascular Circulation; Creatinine; Dia | 2010 |
Effects of hyperglycemia and effects of ketosis on cerebral perfusion, cerebral water distribution, and cerebral metabolism.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain Edema; Cerebrum; Diabetes Mellitus, Experiment | 2012 |
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat | 2012 |
1H chemical shift imaging characterization of human brain tumor and edema.
Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Choline; Creatine; Humans; Hydrogen; Magnetic Resonance | 2002 |
Proton MRS of the peritumoral brain.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Edema; Brain Neoplasms; Epilepsy; Female; Huma | 2005 |
Term neonate prognoses after perinatal asphyxia: contributions of MR imaging, MR spectroscopy, relaxation times, and apparent diffusion coefficients.
Topics: Age Factors; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Brain Edema; Cause of Death; Cerebra | 2006 |
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion | 2006 |
Cerebral proton magnetic resonance spectroscopy in children with diabetic ketoacidosis.
Topics: Adolescent; Aspartic Acid; Brain; Brain Edema; Child; Choline; Consciousness Disorders; Creatine; Di | 2007 |
In vivo proton magnetic resonance spectroscopy for metabolic changes of human brain edema.
Topics: Adult; Aspartic Acid; Brain; Brain Edema; Cerebrovascular Disorders; Creatinine; Female; Humans; Lac | 1994 |
Localised proton spectroscopy and spectroscopic imaging in cerebral gliomas, with comparison to positron emission tomography.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Edema; Carbon Radioisotopes; Creatine; Deoxyglucose; Fl | 1995 |
Astrocytic swelling due to hypotonic or high K+ medium causes inhibition of glutamate and aspartate uptake and increases their release.
Topics: Animals; Aspartic Acid; Astrocytes; Brain; Brain Edema; Brain Ischemia; Excitatory Amino Acid Antago | 1995 |
Attenuation by chlormethiazole of oedema following focal ischaemia in the cerebral cortex of the rat.
Topics: Animals; Aspartic Acid; Body Water; Brain Edema; Cerebral Cortex; Cerebral Infarction; Cerebrovascul | 1994 |
Proton MR spectroscopy of experimental brain tumors in vivo.
Topics: Animals; Aspartic Acid; Blood Glucose; Brain Edema; Brain Neoplasms; Caudate Nucleus; Cell Line; Cho | 1994 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats | 1994 |
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr | 1994 |
L-2-chloropropionic acid-induced neurotoxicity is prevented by MK-801: possible role of NMDA receptors in the neuropathology.
Topics: Administration, Oral; Animals; Aspartic Acid; Autoradiography; Brain Edema; Cerebellum; Dizocilpine | 1996 |
Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ischemic injury in late gestation fetal sheep.
Topics: Animals; Aspartic Acid; Brain Edema; Brain Ischemia; Cytotoxins; Electroencephalography; Extracellul | 1996 |
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel | 1996 |
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons.
Topics: Amygdala; Animals; Aspartic Acid; Brain Edema; Extracellular Space; Glutamic Acid; Glutamine; Glycin | 1996 |
Early changes in peritumorous oedema and contralateral white matter after dexamethasone: a study using proton magnetic resonance spectroscopy.
Topics: Antineoplastic Agents, Hormonal; Aspartic Acid; Brain; Brain Edema; Brain Neoplasms; Choline; Creati | 1997 |
MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Edema; Brain Ischemia; Cerebral Arteries; Choline; Cr | 1997 |
Studies of acute ischemic stroke with proton magnetic resonance spectroscopy: relation between time from onset, neurological deficit, metabolite abnormalities in the infarct, blood flow, and clinical outcome.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Edema; B | 1998 |
Intraoperative microdialysis and tissue-pO2 measurement in human glioma.
Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Cell Death; Female; Frontal Lobe; Glioblastoma; Glutami | 1998 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra | 1999 |
Glutamate-containing parenteral nutrition doubles plasma glutamate: a risk factor in neurosurgical patients with blood-brain barrier damage?
Topics: Asparagine; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Chromatography, High Pressure Liquid; C | 1999 |
Predictive value of proton magnetic resonance spectroscopy in pediatric closed head injury.
Topics: Aspartic Acid; Brain Edema; Chi-Square Distribution; Child; Child, Preschool; Discriminant Analysis; | 2000 |
N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury.
Topics: 2,2'-Dipyridyl; Acute Disease; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Edema; Bra | 2001 |
Proton magnetic resonance spectroscopy of choroid plexus tumors in children.
Topics: Aspartic Acid; Brain Edema; Child, Preschool; Choline; Choroid Plexus; Choroid Plexus Neoplasms; Dia | 2001 |
Metabolic changes in pericontusional oedematous areas in mild head injury evaluated by 1H MRS.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Concussion; Brain Edema; Brain Ischemia; Creati | 2000 |
1H-MR spectroscopic monitoring of posttraumatic metabolism following controlled cortical impact injury: pilot study.
Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Cerebral Cortex; Choline; Creatine; Energy Me | 2000 |
Comparison of NAA measures by MRS and HPLC.
Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Chromatography, High Pressure Liquid; Creatin | 2000 |
Extracellular glutamate and aspartate in head injured patients.
Topics: Adolescent; Adult; Aspartic Acid; Brain Edema; Brain Injuries; Extracellular Space; Female; Glasgow | 2000 |
Hemiconvulsion-hemiplegia-epilepsy syndrome: characteristic early magnetic resonance imaging findings.
Topics: Aspartic Acid; Brain; Brain Edema; Child, Preschool; Dominance, Cerebral; Female; Follow-Up Studies; | 2002 |
Regulatory effect of neurotransmitter by hemofiltration in cardiogenic shock patients after open heart surgery.
Topics: Adolescent; Adult; Aged; Ammonia; Aspartic Acid; Brain Edema; Coronary Artery Bypass; Female; Glasgo | 1991 |
Surface coil spectroscopic imaging: time and spatial evolution of lactate production following fluid percussion brain injury.
Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Brain Injuries; Deuterium; Fourier Analysis; | 1991 |
Pretreatment with the NMDA antagonist dextrorphan reduces cerebral injury following transient focal ischemia in rabbits.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Cerebral Cortex; Dextrorphan; Ischemic Attack, Transient | 1989 |
Calcium dependency of N-methyl-D-aspartate toxicity in slices from the immature rat hippocampus.
Topics: Animals; Aspartic Acid; Brain Edema; Calcium; Female; Hippocampus; In Vitro Techniques; Male; N-Meth | 1989 |
Inhibition of excitatory neurotransmission with kynurenate reduces brain edema in neonatal anoxia.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain Edema; Brain Ischemia; Glutamates; Glutamic Acid; Hy | 1986 |
[Amino acid level in albino rat brain and liver tissue during acute brain edema].
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Edema; gamma-Aminobutyric Acid; Glutamates; Liver; | 1972 |
[Modern therapy of brain edema].
Topics: Aminophylline; Aspartic Acid; Brain Edema; Buffers; Dextrans; Fructose; Glucose; Humans; Hypertonic | 1971 |