aspartic acid has been researched along with Attention Deficit Disorder with Hyperactivity in 35 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Attention Deficit Disorder with Hyperactivity: A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 18 (51.43) | 29.6817 |
| 2010's | 17 (48.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goryunova, AV | 1 |
| Shevchenko, YS | 1 |
| Goryunov, AV | 1 |
| Rizzo, F | 1 |
| Abaei, A | 1 |
| Nespoli, E | 1 |
| Fegert, JM | 1 |
| Hengerer, B | 1 |
| Rasche, V | 1 |
| Boeckers, TM | 1 |
| Toriumi, K | 1 |
| Tanaka, J | 1 |
| Mamiya, T | 1 |
| Alkam, T | 1 |
| Kim, HC | 1 |
| Nitta, A | 1 |
| Nabeshima, T | 1 |
| Aoki, Y | 1 |
| Inokuchi, R | 1 |
| Suwa, H | 1 |
| Aoki, A | 1 |
| Husarova, V | 2 |
| Bittsansky, M | 2 |
| Ondrejka, I | 2 |
| Dobrota, D | 2 |
| Liso Navarro, AA | 1 |
| Sikoglu, EM | 1 |
| Heinze, CR | 1 |
| Rogan, RC | 1 |
| Russell, VA | 1 |
| King, JA | 1 |
| Moore, CM | 1 |
| Unal, GA | 4 |
| Kenar, AN | 1 |
| Herken, H | 4 |
| Kiroglu, Y | 4 |
| Inci Kenar, AN | 3 |
| Güler, H | 1 |
| Albuz, B | 1 |
| Erdal, ME | 1 |
| Bae, S | 1 |
| Han, DH | 1 |
| Kim, SM | 1 |
| Shi, X | 1 |
| Renshaw, PF | 1 |
| Tepeli, E | 1 |
| Ruocco, LA | 3 |
| Gironi Carnevale, UA | 2 |
| Sica, A | 2 |
| Arra, C | 3 |
| Topo, E | 3 |
| Di Giovanni, M | 1 |
| D'Aniello, A | 3 |
| Sadile, AG | 3 |
| Di Pizzo, A | 1 |
| Carnevale, UA | 1 |
| Murolo, M | 1 |
| Curcio, A | 1 |
| Melisi, D | 1 |
| Rimoli, MG | 1 |
| Di Maio, A | 1 |
| Dickstein, DP | 2 |
| Towbin, KE | 2 |
| Van Der Veen, JW | 2 |
| Rich, BA | 1 |
| Brotman, MA | 1 |
| Knopf, L | 2 |
| Onelio, L | 1 |
| Pine, DS | 2 |
| Leibenluft, E | 2 |
| Ferreira, PE | 1 |
| Palmini, A | 1 |
| Bau, CH | 1 |
| Grevet, EH | 1 |
| Hoefel, JR | 1 |
| Rohde, LA | 1 |
| Anés, M | 1 |
| Ferreira, EE | 1 |
| Belmonte-de-Abreu, P | 1 |
| Soliva, JC | 1 |
| Moreno, A | 1 |
| Fauquet, J | 1 |
| Bielsa, A | 1 |
| Carmona, S | 1 |
| Gispert, JD | 1 |
| Rovira, M | 1 |
| Bulbena, A | 1 |
| Vilarroya, O | 1 |
| Yang, P | 1 |
| Wu, MT | 1 |
| Dung, SS | 1 |
| Ko, CW | 1 |
| Rüsch, N | 1 |
| Boeker, M | 1 |
| Büchert, M | 1 |
| Glauche, V | 1 |
| Bohrmann, C | 1 |
| Ebert, D | 3 |
| Lieb, K | 1 |
| Hennig, J | 3 |
| Tebartz Van Elst, L | 3 |
| Jain, M | 1 |
| Vélez, JI | 2 |
| Acosta, MT | 2 |
| Palacio, LG | 1 |
| Balog, J | 1 |
| Roessler, E | 1 |
| Pineda, D | 1 |
| Londoño, AC | 2 |
| Palacio, JD | 2 |
| Arbelaez, A | 2 |
| Lopera, F | 2 |
| Elia, J | 1 |
| Hakonarson, H | 1 |
| Seitz, C | 1 |
| Freitag, CM | 1 |
| Palmason, H | 1 |
| Meyer, J | 1 |
| Romanos, M | 1 |
| Walitza, S | 1 |
| Hemminger, U | 1 |
| Warnke, A | 1 |
| Romanos, J | 1 |
| Renner, T | 1 |
| Jacob, C | 1 |
| Lesch, KP | 1 |
| Swanson, J | 1 |
| Castellanos, FX | 2 |
| Bailey-Wilson, JE | 1 |
| Arcos-Burgos, M | 2 |
| Muenke, M | 2 |
| Pineda, DA | 1 |
| MacMaster, FP | 2 |
| Carrey, N | 1 |
| Sparkes, S | 1 |
| Kusumakar, V | 1 |
| Yeo, RA | 2 |
| Hill, DE | 1 |
| Campbell, RA | 1 |
| Vigil, J | 2 |
| Petropoulos, H | 1 |
| Hart, B | 1 |
| Zamora, L | 1 |
| Brooks, WM | 2 |
| Courvoisie, H | 1 |
| Hooper, SR | 1 |
| Fine, C | 1 |
| Kwock, L | 1 |
| Castillo, M | 2 |
| Sparkes, SJ | 1 |
| Carrey, NC | 1 |
| Fayed, N | 1 |
| Modrego, PJ | 1 |
| Margari, L | 1 |
| Ventura, P | 1 |
| Portoghese, C | 1 |
| Presicci, A | 1 |
| Buttiglione, M | 1 |
| Di Cuonzo, F | 1 |
| Perlov, E | 1 |
| Philipsen, A | 1 |
| Hesslinger, B | 2 |
| Buechert, M | 1 |
| Ahrendts, J | 1 |
| Feige, B | 1 |
| Bubl, E | 1 |
| Kronenberg, G | 1 |
| Ende, G | 1 |
| Alm, B | 1 |
| Deuschle, M | 1 |
| Heuser, I | 1 |
| Colla, M | 1 |
| Hill, D | 1 |
| Campbell, R | 1 |
| Thiel, T | 1 |
| Jin, Z | 1 |
| Zang, YF | 1 |
| Zeng, YW | 1 |
| Zhang, L | 1 |
| Wang, YF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain[NCT01844700] | Phase 4 | 14 participants (Actual) | Interventional | 2013-07-31 | Terminated (stopped due to very slow recruitment, no sufficient results) | ||
| Measuring Glutamate and GABA Brain Levels in Adults With Attention Deficit Hyperactivity Disorder (ADHD) Using Magnetic Resonance Spectroscopy (MRS)[NCT04823364] | 60 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | percentage of weight change (Mean) |
|---|---|
| Ziprasidone | 11.58 |
| Aripiprazole, Quetiapine, Risperidone | 5.66 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI percentile (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | 37.67 | 62.5 |
| Ziprasidone | 32 | 59 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI z-score (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | -0.37 | 0.38 |
| Ziprasidone | -0.51 | 0.22 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | lbs (Mean) | |
|---|---|---|
| baseline | week 12 (n=1,2) | |
| Aripiprazole, Quetiapine, Risperidone | 118.5 | 141 |
| Ziprasidone | 120.5 | 151 |
2 reviews available for aspartic acid and Attention Deficit Disorder with Hyperactivity
| Article | Year |
|---|---|
[Cogitum in children's neurology and psychiatry (experience in the practical use)].
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Child; Choline; Creatine; Human | 2019 |
Age-related change of neurochemical abnormality in attention-deficit hyperactivity disorder: a meta-analysis.
Topics: Age Factors; Aging; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Humans; Magnetic R | 2013 |
3 trials available for aspartic acid and Attention Deficit Disorder with Hyperactivity
| Article | Year |
|---|---|
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.
Topics: Adolescent; Antimanic Agents; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar | 2009 |
Increased NAA and reduced choline levels in the anterior cingulum following chronic methylphenidate. A spectroscopic test-retest study in adult ADHD.
Topics: Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Choline; Dopamine Uptake | 2008 |
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation.
Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Dis | 2008 |
30 other studies available for aspartic acid and Attention Deficit Disorder with Hyperactivity
| Article | Year |
|---|---|
Aripiprazole and Riluzole treatment alters behavior and neurometabolites in young ADHD rats: a longitudinal
Topics: Animals; Antipsychotic Agents; Aripiprazole; Aspartic Acid; Attention Deficit Disorder with Hyperact | 2017 |
Shati/Nat8l knockout mice show behavioral deficits ameliorated by atomoxetine and methylphenidate.
Topics: Acetyltransferases; Amphetamine-Related Disorders; Animals; Aspartic Acid; Atomoxetine Hydrochloride | 2018 |
Prefrontal grey and white matter neurometabolite changes after atomoxetine and methylphenidate in children with attention deficit/hyperactivity disorder: a (1)H magnetic resonance spectroscopy study.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Aspartic Acid; Atomoxetine Hydrochloride; Attention; Atten | 2014 |
Effect of diet on brain metabolites and behavior in spontaneously hypertensive rats.
Topics: Animals; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Creatine; Dietary Fats | 2014 |
Correlations of ADHD symptoms with neurometabolites measured by 1H magnetic resonance spectroscopy.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Child; Choline; Creatine; Female; Glut | 2014 |
Association of adult attention deficit hyperactivity disorder subtypes and response to methylphenidate HCL treatment: A magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys | 2015 |
Relationship between the DAT1 gene and the effects of methylphenidate administration in adult attention deficit hyperactivity disorder: a magnetic resonance spectroscopy study.
Topics: Administration, Oral; Adolescent; Adult; Alleles; Aspartic Acid; Attention Deficit Disorder with Hyp | 2016 |
Neurochemical correlates of internet game play in adolescents with attention deficit hyperactivity disorder: A proton magnetic resonance spectroscopy (MRS) study.
Topics: Adolescent; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Glutamic Acid; Glut | 2016 |
Relationship between the SNAP-25 gene and the effects of methylphenidate on the anterior cingulate cortex of patients with adult attention deficit hyperactivity disorder: a magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulan | 2016 |
Effects of methylphenidate treatment on the cerebellum in adult attention-deficit hyperactivity disorder: a magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys | 2017 |
Differential prepuberal handling modifies behaviour and excitatory amino acids in the forebrain of the Naples High-Excitability rats.
Topics: Animals; Aspartic Acid; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; | 2009 |
Excitatory amino acids in the forebrain of the Naples high-excitability rats: neurochemical and behavioural effects of subchronic D-aspartate and its diethyl ester prodrug.
Topics: Animals; Aspartic Acid; Attention; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; | 2009 |
Elevated forebrain excitatory L-glutamate, L-aspartate and D-aspartate in the Naples high-excitability rats.
Topics: Animals; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Chromatogra | 2009 |
Differentiating attention-deficit/hyperactivity disorder inattentive and combined types: a (1)H-magnetic resonance spectroscopy study of fronto-striato-thalamic regions.
Topics: Adolescent; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Choline; Corpus Striatum; | 2009 |
Cerebellar neurometabolite abnormalities in pediatric attention/deficit hyperactivity disorder: a proton MR spectroscopic study.
Topics: Amino Acids; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Cer | 2010 |
Short-TE proton magnetic resonance spectroscopy investigation in adolescents with attention-deficit hyperactivity disorder.
Topics: Adolescent; Analysis of Variance; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Chil | 2010 |
Neurochemical alterations in women with borderline personality disorder and comorbid attention-deficit hyperactivity disorder.
Topics: Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder | 2010 |
A cooperative interaction between LPHN3 and 11q doubles the risk for ADHD.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Case-Control Studies; Choline; | 2012 |
Analysis of brain metabolism by proton magnetic resonance spectroscopy (1H-MRS) in attention-deficit/hyperactivity disorder suggests a generalized differential ontogenic pattern from controls.
Topics: Adolescent; Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Case-Control | 2012 |
Proton spectroscopy in medication-free pediatric attention-deficit/hyperactivity disorder.
Topics: Adolescent; Amino Acids; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Basal Ganglia | 2003 |
Proton magnetic resonance spectroscopy investigation of the right frontal lobe in children with attention-deficit/hyperactivity disorder.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Child; Female; Frontal Lobe; Functiona | 2003 |
Neurometabolic functioning and neuropsychological correlates in children with ADHD-H: preliminary findings.
Topics: Aspartic Acid; Attention; Attention Deficit Disorder with Hyperactivity; Brain Chemistry; Case-Contr | 2004 |
Proton magnetic resonance spectroscopy and cognitive function in pediatric attention-deficit/hyperactive disorder.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain Stem; Child; Choline; Cognition | 2004 |
Autism and ADHD: common disorders, elusive explanations.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; Brain Chemistry; Ce | 2005 |
Comparative study of cerebral white matter in autism and attention-deficit/hyperactivity disorder by means of magnetic resonance spectroscopy.
Topics: Analysis of Variance; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Autistic Disorde | 2005 |
Brain magnetic resonance spectroscopy in Sydenham's chorea and ADHD.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Brain; Child; Choline; Chorea; Creatin | 2006 |
Reduced cingulate glutamate/glutamine-to-creatine ratios in adult patients with attention deficit/hyperactivity disorder -- a magnet resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Choline; Creatine; Dominance, C | 2007 |
Developmental instability and working memory ability in children: a magnetic resonance spectroscopy investigation.
Topics: Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Child; Choline; Creatine; Energy Metab | 2000 |
Attention-deficit disorder in adults with or without hyperactivity: where is the difference? A study in humans using short echo (1)H-magnetic resonance spectroscopy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Corpus St | 2001 |
Striatal neuronal loss or dysfunction and choline rise in children with attention-deficit hyperactivity disorder: a 1H-magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Cell Death; Child; Choline | 2001 |