Page last updated: 2024-11-08

aspartic acid and Astrocytoma

aspartic acid has been researched along with Astrocytoma in 59 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research Excerpts

ExcerptRelevanceReference
"The choline/N-acetyl-aspartate (Cho/NAA) ratio, obtained by the multivoxel spectroscopy with short echo time (TE), was evaluated, in the histological grading of the brain astrocytomas (grades I, II and III-IV) in comparison with the normal cerebral parenchyma."9.12[Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas]. ( Aragão, Mde F; Araújo, N; Azevedo Filho, HR; Leite, Cda C; Melo, RV; Otaduy, MC; Silva, JL; Valença, MM; Victor, EG, 2007)
"The choline/N-acetyl-aspartate (Cho/NAA) ratio, obtained by the multivoxel spectroscopy with short echo time (TE), was evaluated, in the histological grading of the brain astrocytomas (grades I, II and III-IV) in comparison with the normal cerebral parenchyma."5.12[Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas]. ( Aragão, Mde F; Araújo, N; Azevedo Filho, HR; Leite, Cda C; Melo, RV; Otaduy, MC; Silva, JL; Valença, MM; Victor, EG, 2007)
"In vivo magnetic resonance spectroscopy (MRS) studies of glial brain tumours reported that higher grade of astrocytoma is associated with increased level of choline-containing compounds (Cho) and decreased levels of N-acetylaspartate (NAA) and creatine and phosphocreatine (Cr)."3.73In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy. ( Belan, V; Béres, A; De Riggo, J; Dobrota, D; Galanda, M; Likavcanová, K; Liptaj, T; Mlynárik, V; Prónayová, N, 2005)
"The ratios of choline (Cho) to N-acetylaspartate (NAA) and Cho to creatine (Cr) in those with high-grade astrocytomas (n=4) were significantly higher than in those with low-grade astrocytomas (n=17) (t=2."3.73In vivo research in astrocytoma cell proliferation with 1H-magnetic resonance spectroscopy: correlation with histopathology and immunohistochemistry. ( Chen, J; Chen, XL; Huang, SL; Li, T, 2006)
"Diffusion tensor imaging (DTI) and MR spectroscopy are noninvasive, quantitative tools for the preoperative assessment of gliomas with which the quantitative parameter fractional anisotropy (FA) and the concentration of neurometabolites N-acetylaspartate (NAA), choline (Cho), creatine (Cr) of the brain can be determined."3.73Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study. ( Ding, XQ; Fiehler, J; Goebell, E; Hagel, C; Heese, O; Kucinski, T; Nietz, S; Paustenbach, S; Westphal, M; Zeumer, H, 2006)
" The concentration of taurine (Tau) in medulloblastomas was 29."3.72In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard. ( Harada, K; Houkin, K; Tong, Z; Yamaki, T, 2004)
"Seven patients responded to tamoxifen therapy (three with glioblastomas multiforme; four with anaplastic astrocytomas), and nine did not (six with glioblastomas multiforme; three with anaplastic astrocytomas)."3.70Using proton magnetic resonance spectroscopic imaging to predict in vivo the response of recurrent malignant gliomas to tamoxifen chemotherapy. ( Arnold, DL; Caramanos, Z; Langleben, A; LeBlanc, R; Preul, MC; Shenouda, G; Villemure, JG, 2000)
" The NAA (N-acetylaspartate)/Cho (choline) ratio of Grade 2 astrocytoma was higher than that of Grade 4."3.69Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy. ( Bandou, K; Harada, M; Kannuki, S; Miyoshi, H; Nishitani, H; Tanouchi, M, 1995)
"(a) Hamartomas showed higher N-acetyl aspartate/creatine, creatine/choline, and N-acetyl aspartate/choline ratios than gliomas."3.69Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation. ( Castillo, M; Green, C; Greenwood, R; Kwock, L; Schiro, S; Smith, K; Wilson, D, 1995)
"The choline/NAA ratio was 3."2.40Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas. ( Ball, WS; Ballard, E; Dunn, RS; Egnaczyk, GF; Holland, SK; Hwang, JH, 1998)
"There were 19 pituitary adenomas, 7 gliomas, 5 craniopharyngiomas, 3 chordomas, meningioma, hemangiopericytoma, malignant lymphoma, germinoma, Rathke cleft cyst, and hypothalamic hamartoma (one of each)."1.35Possible role of single-voxel (1)H-MRS in differential diagnosis of suprasellar tumors. ( Amano, K; Chernov, MF; Hori, T; Iseki, H; Kawamata, T; Kubo, O; Muragaki, Y; Nakamura, R; Ono, Y; Suzuki, T; Takakura, K, 2009)
"Ten patients with untreated gliomas were examined on a 1."1.32Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas. ( Buslei, R; Fahlbusch, R; Ganslandt, O; Gruber, S; Moser, E; Nimsky, C; Stadlbauer, A, 2004)
"We examined 120 patients with brain tumors using a 1."1.31In vivo proton magnetic resonance spectroscopy of brain tumors. ( Fountas, KN; Gotsis, SD; Johnston, KW; Kapsalaki, EZ; Kapsalakis, JZ; Papadakis, N; Robinson, JS; Smisson , HF, 2000)
"Aspirated pus from one patient with brain abscess was examined using ex vivo proton MR spectroscopy."1.31Discrimination of brain abscess and cystic tumor by in vivo proton magnetic resonance spectroscopy. ( Kadota, O; Kikuchi, K; Kohno, K; Kumon, Y; Miki, H; Ohue, S; Sakaki, S, 2001)
"Proton MRS of pediatric posterior fossa tumors seems to be helpful in prediction of tumor grading and histology."1.31[Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors]. ( Biegański, T; Kreisel, J; Liberski, PP; Nowosławska, E; Polis, L; Zakrzewski, K, 2001)
"Meningiomas were further characterized by the presence of alanine."1.29Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours. ( Blackband, SJ; Horsman, A; Lowry, M; Manton, DJ, 1995)
"Eleven primitive neuroectodermal tumors (patient age, 2 to 12 years; mean, 7 years), 11 low-grade astrocytomas (age, 2 to 16 years; mean, 9 years), 4 ependymomas (age, 1 to 6 years; mean, 4 years), 1 mixed glioma ependymo-astrocytoma (age, 11 years), 1 anaplastic ependymoma (age, 7 years), 1 ganglioglioma (age, 14 years), and 1 malignant teratoma (age, 6 days) were studied."1.29Proton MR spectroscopy of pediatric cerebellar tumors. ( Bilaniuk, LT; Cnaan, A; Haselgrove, JC; Rorke, LB; Sutton, LN; Wang, Z; Zhao, H; Zimmerman, RA, 1995)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19905 (8.47)18.7374
1990's16 (27.12)18.2507
2000's30 (50.85)29.6817
2010's8 (13.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlin, D1
Babourina-Brooks, B1
Davies, NP1
Wilson, M1
Peet, AC1
Saito, K1
Toda, M1
Yoshida, K1
Tamrazi, B1
Nelson, MD1
Blüml, S1
Carvalho-Neto, Ad1
Bruck, I1
Antoniuk, SA1
Marchiori, E1
Gasparetto, EL1
Chernov, MF1
Kawamata, T1
Amano, K1
Ono, Y1
Suzuki, T1
Nakamura, R1
Muragaki, Y1
Iseki, H1
Kubo, O1
Hori, T1
Takakura, K1
Stadlbauer, A3
Buchfelder, M2
Doelken, MT1
Hammen, T2
Ganslandt, O3
Rueckriegel, SM1
Driever, PH1
Bruhn, H1
Wächter, T1
Engeholm, M1
Bisdas, S1
Schittenhelm, J1
Gasser, T1
Krüger, R1
Vettukattil, R1
Gulati, M1
Sjøbakk, TE1
Jakola, AS1
Kvernmo, NA1
Torp, SH1
Bathen, TF1
Gulati, S1
Gribbestad, IS1
Ali, ZS1
Lang, SS1
Sutton, LN3
Murphy, M2
Loosemore, A1
Clifton, AG1
Howe, FA2
Tate, AR1
Cudlip, SA2
Wilkins, PR1
Griffiths, JR2
Bell, BA2
Barton, SJ1
Stubbs, M1
Saunders, DE1
Wilkins, P1
Opstad, KS1
Doyle, VL1
McLean, MA1
Bulakbasi, N1
Kocaoglu, M1
Ors, F1
Tayfun, C1
Uçöz, T1
Lichy, MP2
Bachert, P2
Henze, M1
Lichy, CM1
Debus, J2
Schlemmer, HP2
Vuori, K1
Kankaanranta, L1
Häkkinen, AM2
Gaily, E1
Valanne, L1
Granström, ML1
Joensuu, H1
Blomstedt, G1
Paetau, A2
Lundbom, N2
Tong, Z1
Yamaki, T1
Harada, K1
Houkin, K2
Cirak, B1
Horská, A1
Barker, PB1
Burger, PC1
Carson, BS1
Avellino, AM1
Moser, E2
Gruber, S2
Buslei, R1
Nimsky, C2
Fahlbusch, R1
Magalhaes, A1
Godfrey, W1
Shen, Y1
Hu, J1
Smith, W1
Nishibayashi, H1
Matsuda, Y1
Uematsu, Y1
Nakao, N1
Terada, T1
Itakura, T1
Pulkkinen, J1
Kauppinen, RA1
Hiltunen, Y1
Likavcanová, K1
Dobrota, D1
Liptaj, T1
Prónayová, N1
Mlynárik, V1
Belan, V1
Galanda, M1
Béres, A1
De Riggo, J1
Chen, J1
Huang, SL1
Li, T1
Chen, XL1
Hamprecht, F1
Weber, MA1
Schulz-Ertner, D1
Kauczor, HU1
Goebell, E1
Fiehler, J1
Ding, XQ1
Paustenbach, S1
Nietz, S1
Heese, O1
Kucinski, T1
Hagel, C1
Westphal, M1
Zeumer, H1
Engelhorn, T1
Aragão, Mde F1
Otaduy, MC1
Melo, RV1
Azevedo Filho, HR1
Victor, EG1
Silva, JL1
Araújo, N1
Leite, Cda C1
Valença, MM1
Zhang, K1
Li, C1
Liu, Y1
Li, L1
Ma, X1
Meng, X1
Feng, D1
Hagberg, G1
Burlina, AP1
Mader, I1
Roser, W1
Radue, EW1
Seelig, J1
McBride, DQ1
Miller, BL1
Nikas, DL1
Buchthal, S1
Chang, L1
Chiang, F1
Booth, RA1
Harada, M1
Tanouchi, M1
Nishitani, H1
Miyoshi, H1
Bandou, K1
Kannuki, S1
Castillo, M2
Green, C1
Kwock, L2
Smith, K1
Wilson, D1
Schiro, S1
Greenwood, R1
O'Neill, CM1
Ball, SG1
Vaughan, PF1
Wehrli, SL1
Gennarelli, L1
Wang, Z2
Zimmerman, R1
Bonner, K1
Rorke, LB2
Kamada, K1
Hida, K1
Matsuzawa, H1
Iwasaki, Y1
Abe, H1
Nakada, T1
Manton, DJ1
Lowry, M1
Blackband, SJ1
Horsman, A1
Preul, MC2
Caramanos, Z2
Collins, DL1
Villemure, JG2
Leblanc, R2
Olivier, A1
Pokrupa, R1
Arnold, DL2
Tien, RD1
Lai, PH1
Smith, JS1
Lazeyras, F1
Cnaan, A1
Haselgrove, JC1
Zhao, H1
Bilaniuk, LT1
Zimmerman, RA1
Hwang, JH1
Egnaczyk, GF1
Ballard, E1
Dunn, RS1
Holland, SK1
Ball, WS1
Lazareff, JA1
Bockhorst, KH1
Curran, J1
Olmstead, C1
Alger, JR1
Meyerand, ME1
Pipas, JM1
Mamourian, A1
Tosteson, TD1
Dunn, JF1
Shenouda, G1
Langleben, A1
Graves, EE1
Nelson, SJ1
Vigneron, DB1
Chin, C1
Verhey, L1
McDermott, M1
Larson, D1
Sneed, PK1
Chang, S1
Prados, MD1
Lamborn, K1
Dillon, WP1
Ricci, PE1
Pitt, A1
Keller, PJ1
Coons, SW1
Heiserman, JE1
Sak, K1
Uri, A1
Enkvist, E1
Raidaru, G1
Subbi, J1
Kelve, M1
Järv, J1
Smith, JK1
Fountas, KN1
Kapsalaki, EZ1
Gotsis, SD1
Kapsalakis, JZ1
Smisson , HF1
Johnston, KW1
Robinson, JS1
Papadakis, N1
Kadota, O1
Kohno, K1
Ohue, S1
Kumon, Y1
Sakaki, S1
Kikuchi, K1
Miki, H1
Liu, H1
Hall, WA1
Martin, AJ1
Truwit, CL1
Ishimaru, H1
Morikawa, M1
Iwanaga, S1
Kaminogo, M1
Ochi, M1
Hayashi, K1
Zakrzewski, K1
Kreisel, J1
Polis, L1
Nowosławska, E1
Liberski, PP1
Biegański, T1
Haber, B1
Hutchison, HT1
Henriksen, O1
Wieslander, S1
Gjerris, F1
Jensen, KM1
Segebarth, CM1
Balériaux, DF1
Luyten, PR1
den Hollander, JA1
Erecińska, M1
Troeger, MB1
Wilson, DF1
Silver, IA1
Promyslov, MS1
Fischer, W1
Müller, E1
Snodgrass, SR1
Iversen, LL1

Reviews

1 review available for aspartic acid and Astrocytoma

ArticleYear
Proton MR spectroscopic characteristics of pediatric pilocytic astrocytomas.
    AJNR. American journal of neuroradiology, 1998, Volume: 19, Issue:3

    Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Choline; Humans; Infant; Lacti

1998

Trials

2 trials available for aspartic acid and Astrocytoma

ArticleYear
[Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas].
    Arquivos de neuro-psiquiatria, 2007, Volume: 65, Issue:2A

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Chol

2007
Evaluation of invasiveness of astrocytoma using 1H-magnetic resonance spectroscopy: correlation with expression of matrix metalloproteinase-2.
    Neuroradiology, 2007, Volume: 49, Issue:11

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Hum

2007

Other Studies

56 other studies available for aspartic acid and Astrocytoma

ArticleYear
Variation of T
    Journal of magnetic resonance imaging : JMRI, 2019, Volume: 49, Issue:1

    Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Child; Choline; Creatine; Female; Humans; Magnet

2019
Pilocytic astrocytoma with anaplastic features presenting good long-term clinical course after surgery alone: a case report.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:1

    Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Humans; Magnetic Resonance Imaging; Magnetic Res

2015
MRS of pilocytic astrocytoma: The peak at 2 ppm may not be NAA.
    Magnetic resonance in medicine, 2017, Volume: 78, Issue:2

    Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Child; Child, Preschool; Humans; Inf

2017
Proton MR spectroscopy of the foramen of Monro region in patients with tuberous sclerosis complex.
    Arquivos de neuro-psiquiatria, 2008, Volume: 66, Issue:2B

    Topics: Amino Acids; Aspartic Acid; Astrocytoma; Basal Ganglia; Biomarkers, Tumor; Brain Chemistry; Case-Con

2008
Possible role of single-voxel (1)H-MRS in differential diagnosis of suprasellar tumors.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:2

    Topics: Adult; Aspartic Acid; Astrocytoma; Chi-Square Distribution; Choline; Craniopharyngioma; Creatine; Di

2009
Magnetic resonance spectroscopic imaging for visualization of the infiltration zone of glioma.
    Central European neurosurgery, 2011, Volume: 72, Issue:2

    Topics: Adult; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Choline; Data Interpretation, Statistica

2011
Supratentorial neurometabolic alterations in pediatric survivors of posterior fossa tumors.
    International journal of radiation oncology, biology, physics, 2012, Mar-01, Volume: 82, Issue:3

    Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Astro

2012
Slowly progressive Parkinson syndrome due to thalamic butterfly astrocytoma.
    Neurology, 2011, Jul-26, Volume: 77, Issue:4

    Topics: Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Brain Stem; Choline; Glial Fibrillary Acidic Prot

2011
Differentiating diffuse World Health Organization grade II and IV astrocytomas with ex vivo magnetic resonance spectroscopy.
    Neurosurgery, 2013, Volume: 72, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Fema

2013
Conservative management of presumed low-grade gliomas in the asymptomatic pediatric population.
    World neurosurgery, 2014, Volume: 81, Issue:2

    Topics: Adolescent; Aspartic Acid; Astrocytoma; Asymptomatic Diseases; Brain Neoplasms; Child; Child, Presch

2014
The contribution of proton magnetic resonance spectroscopy (1HMRS) to clinical brain tumour diagnosis.
    British journal of neurosurgery, 2002, Volume: 16, Issue:4

    Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatinine; Humans; Inositol; Magn

2002
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
    Magnetic resonance in medicine, 2003, Volume: 49, Issue:2

    Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inosi

2003
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creat

2003
Monitoring individual response to brain-tumour chemotherapy: proton MR spectroscopy in a patient with recurrent glioma after stereotactic radiotherapy.
    Neuroradiology, 2004, Volume: 46, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Astrocytoma; Brain Neoplasms;

2004
Low-grade gliomas and focal cortical developmental malformations: differentiation with proton MR spectroscopy.
    Radiology, 2004, Volume: 230, Issue:3

    Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Cerebral Cortex; Child; Choline; Creatine; Diagnosis,

2004
In vivo quantification of the metabolites in normal brain and brain tumors by proton MR spectroscopy using water as an internal standard.
    Magnetic resonance imaging, 2004, Volume: 22, Issue:5

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellar Neoplasms; C

2004
Proton magnetic resonance spectroscopic imaging in pediatric pilomyxoid astrocytoma.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2005, Volume: 21, Issue:5

    Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Child, Preschool; Choline; Creatine; Female; Humans; In

2005
Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas.
    NeuroImage, 2004, Volume: 23, Issue:2

    Topics: Adult; Algorithms; Aspartic Acid; Astrocytoma; Automation; Biopsy; Brain Chemistry; Brain Mapping; B

2004
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
    Academic radiology, 2005, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatin

2005
[A case of high grade astrocytoma arising in the hand area of precentral gyrus].
    No to shinkei = Brain and nerve, 2005, Volume: 57, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Astrocytoma; Brain Neoplasms;

2005
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
    European journal of radiology, 2005, Volume: 56, Issue:2

    Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glio

2005
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
    General physiology and biophysics, 2005, Volume: 24, Issue:3

    Topics: Aspartic Acid; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Choline; Chromium; Creatine; Gliobla

2005
In vivo research in astrocytoma cell proliferation with 1H-magnetic resonance spectroscopy: correlation with histopathology and immunohistochemistry.
    Neuroradiology, 2006, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Choline; Creatine; Fema

2006
[Application of (1)H MR spectroscopic imaging in radiation oncology: choline as a marker for determining the relative probability of tumor progression after radiation of glial brain tumors].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2006, Volume: 178, Issue:6

    Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Choline; Combined

2006
Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Adult; Aged; Anisotropy; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Size; Choline; Cre

2006
Changes in fiber integrity, diffusivity, and metabolism of the pyramidal tract adjacent to gliomas: a quantitative diffusion tensor fiber tracking and MR spectroscopic imaging study.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Creatine; Diffusion Magnetic Resonance Ima

2007
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
    Magnetic resonance in medicine, 1995, Volume: 34, Issue:2

    Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminan

1995
Analysis of brain tumors using 1H magnetic resonance spectroscopy.
    Surgical neurology, 1995, Volume: 44, Issue:2

    Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Glioblastoma; Humans; Lactates; Magneti

1995
Non-invasive characterization of brain tumor by in-vivo proton magnetic resonance spectroscopy.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:3

    Topics: Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Ependymoma; Glioma; Humans; Magnetic

1995
Proton MR spectroscopy in patients with neurofibromatosis type 1: evaluation of hamartomas and clinical correlation.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Brain; Brain Diseases; Brain Neoplasms; Cerebellar Di

1995
Effects of ischaemic conditions on uptake of glutamate, aspartate, and noradrenaline by cell lines derived from the human nervous system.
    Journal of neurochemistry, 1994, Volume: 63, Issue:2

    Topics: Aspartic Acid; Astrocytoma; Biological Transport; Cell Hypoxia; Cell Line; Glutamates; Glutamic Acid

1994
High-resolution 1H-magnetic resonance spectroscopy of pediatric posterior fossa tumors in vitro.
    Journal of neurosurgery, 1994, Volume: 81, Issue:3

    Topics: Adolescent; Alanine; Amino Acids; Animals; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cerebellar N

1994
Localized proton spectroscopy of focal brain pathology in humans: significant effects of edema on spin-spin relaxation time.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:5

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain; Brain Edema; Brain Ischemia; Brain Neoplasms; Cerebr

1994
Determination of proton metabolite concentrations and relaxation parameters in normal human brain and intracranial tumours.
    NMR in biomedicine, 1995, Volume: 8, Issue:3

    Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cerebellum; Creatine; Humans; Magnetic Resonance

1995
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.
    Nature medicine, 1996, Volume: 2, Issue:3

    Topics: Adult; Alanine; Aspartic Acid; Astrocytoma; Biomarkers; Brain; Brain Neoplasms; Choline; Creatine; D

1996
Single-voxel proton brain spectroscopy exam (PROBE/SV) in patients with primary brain tumors.
    AJR. American journal of roentgenology, 1996, Volume: 167, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Chemistry; Brain Neoplasms; Choline; Crea

1996
Proton MR spectroscopy of pediatric cerebellar tumors.
    AJNR. American journal of neuroradiology, 1995, Volume: 16, Issue:9

    Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain Chemistry; Cerebellar Neoplasms; Child; Child, Prescho

1995
Pediatric low-grade gliomas: prognosis with proton magnetic resonance spectroscopic imaging.
    Neurosurgery, 1998, Volume: 43, Issue:4

    Topics: Adolescent; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Division; Child; Child, Prescho

1998
Classification of biopsy-confirmed brain tumors using single-voxel MR spectroscopy.
    AJNR. American journal of neuroradiology, 1999, Volume: 20, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Astrocytoma; Biopsy; Body Water; Brain Neoplasms;

1999
Using proton magnetic resonance spectroscopic imaging to predict in vivo the response of recurrent malignant gliomas to tamoxifen chemotherapy.
    Neurosurgery, 2000, Volume: 46, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Hormonal; Aspartic Acid; Astro

2000
A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas.
    Neurosurgery, 2000, Volume: 46, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Choline; Creatine; Female; Glioblastoma; Humans; Lactic Aci

2000
Effect of voxel position on single-voxel MR spectroscopy findings.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:2

    Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glio

2000
Adenosine-derived non-phosphate antagonists for P2Y(1) purinoceptors.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Aspartic Acid; Astrocytoma; Dose-Response Relationship, Drug; Huma

2000
Correlation of myo-inositol levels and grading of cerebral astrocytomas.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Chil

2000
In vivo proton magnetic resonance spectroscopy of brain tumors.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:2

    Topics: Adult; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Brain; Brain Abscess; Brain Neoplasms; Choline

2000
Discrimination of brain abscess and cystic tumor by in vivo proton magnetic resonance spectroscopy.
    Neurologia medico-chirurgica, 2001, Volume: 41, Issue:3

    Topics: Acetates; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Bacteria; Biomarkers; Brain Abscess; Child;

2001
An efficient chemical shift imaging scheme for magnetic resonance-guided neurosurgery.
    Journal of magnetic resonance imaging : JMRI, 2001, Volume: 14, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Biopsy; Brain; Brain Mapping; Brain Neop

2001
Differentiation between high-grade glioma and metastatic brain tumor using single-voxel proton MR spectroscopy.
    European radiology, 2001, Volume: 11, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chil

2001
[Clinical application of proton magnetic resonance spectroscopy for differential diagnosis of pediatric posterior fossa tumors].
    Neurologia i neurochirurgia polska, 2001, Volume: 35 Suppl 5

    Topics: Adolescent; Aspartic Acid; Astrocytoma; Child; Child, Preschool; Choline; Creatine; Diagnosis, Diffe

2001
Uptake of neurotransmitters and precursors by clonal cell lines of neural origin.
    Advances in experimental medicine and biology, 1976, Volume: 69

    Topics: Amino Acids; Aminooxyacetic Acid; Aspartic Acid; Astrocytoma; Biogenic Amines; Cell Line; Cell Membr

1976
In vivo 1H-spectroscopy of human intracranial tumors at 1.5 tesla. Preliminary experience at a clinical installation.
    Acta radiologica (Stockholm, Sweden : 1987), 1991, Volume: 32, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactate

1991
Detection of metabolic heterogeneity of human intracranial tumors in vivo by 1H NMR spectroscopic imaging.
    Magnetic resonance in medicine, 1990, Volume: 13, Issue:1

    Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Creatine; Glioma; Humans; Magnetic Resona

1990
The role of glial cells in regulation of neurotransmitter amino acids in the external environment. II. Mechanism of aspartate transport.
    Brain research, 1986, Mar-26, Volume: 369, Issue:1-2

    Topics: Animals; Aspartic Acid; Astrocytoma; Cell Line; Cell Membrane Permeability; Chlorides; Membrane Pote

1986
Some biochemical characteristics of neuroglia as deduced by glial tumor biochemical analysis.
    Journal of neurosurgery, 1971, Volume: 34, Issue:3

    Topics: Aminobutyrates; Aspartic Acid; Astrocytoma; Brain; Brain Chemistry; Brain Neoplasms; Carboxy-Lyases;

1971
[Activities of glutamate dehydrogenase and aspartate aminotransferase in human brain tumors].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1972, Volume: 115, Issue:1

    Topics: Adenoma; Aspartate Aminotransferases; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Craniopha

1972
Amino acid uptake into human brain tumors.
    Brain research, 1974, Aug-09, Volume: 76, Issue:1

    Topics: Absorption; Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Astrocytoma; Autoradiography; Brain

1974