Compounds > aspartic acid
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aspartic acid and Astrocytoma, Grade IV

aspartic acid has been researched along with Astrocytoma, Grade IV in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19903 (5.00)18.7374
1990's8 (13.33)18.2507
2000's22 (36.67)29.6817
2010's21 (35.00)24.3611
2020's6 (10.00)2.80

Authors

AuthorsStudies
Kurappalli, RK; Mekala, JR; Moparthi, NR; Ramalingam, P1
Inoue, A; Kanemura, Y; Kitazawa, R; Kunieda, T; Kusakabe, K; Nakamura, Y; Nishikawa, M; Ohnishi, T; Ohtsuka, Y; Ozaki, S; Shigekawa, S; Suehiro, S; Tanaka, J; Watanabe, H; Yamashita, D; Yano, H1
Charissoux, M; Cohen-Jonathan Moyal, E; Desmoulin, F; Gilhodes, J; Ken, S; Laprie, A; Lotterie, JA; Lubrano, V; Magné, N; Noël, G; Péran, P; Roques, M; Sunyach, MP; Tensaouti, F; Truc, G1
Anselmo Rios Piedra, E; Cruz-Priego, GA; Durand-Muñoz, C; Flores-Alvarez, E; Moreno-Jimenez, S; Roldan-Valadez, E1
Cui, CX; Duan, CF; Liu, XJ; Su, HW; Wang, JC; Zhao, JP1
Bloch, J; Comment, A; Cudalbu, C; Gruetter, R; Gusyatiner, O; Hamou, MF; Hegi, ME; Lanz, B; Mishkovsky, M; Vassallo, I1
Chen, F; Chen, L; Li, L; Li, P; Li, Z; Tu, L; Weng, C; Xie, W1
Bruzzone, MG; Cantini, G; Cominelli, M; Corbetta, C; Di Ianni, N; Finocchiaro, G; Patanè, M; Pellegatta, S; Pisati, F; Poliani, PL; Pollo, B; Zucca, I1
Cooper, LAD; Gurbani, SS; Maudsley, AA; Sheriff, S; Shim, H1
Biris, AS; Bratu, I; Casciano, D; Florea, A; Florian, S; Olenic, L; Orza, A; Pall, E; Pana, O; Soriţău, O; Tomuleasa, C1
Barboriak, DP; Bokstein, F; Boxerman, JL; Gilbert, MR; McKinstry, RC; Ratai, EM; Safriel, Y; Snyder, BS; Sorensen, AG; Zhang, Z1
Anderson, CM; Bayouth, JE; Buatti, JM; Capizzano, AA; Clerkin, PP; Magnotta, V; McGuire, SM; Morris, A; Muruganandham, M; Smith, BJ; Smith, MC1
Gupta, RK; Huang, K; Ishkanian, F; Markoe, A; Maudsley, AA; Padgett, K; Panoff, J; Parra, NA; Roy, B; Stoyanova, R; Walker, GR1
Berry, I; Catalaa, I; Celsis, P; Cohen-Jonathan Moyal, E; Deviers, A; Filleron, T; Ken, S; Laprie, A; Laruelo, A; Lubrano, V; Mogicato, G; Rowland, B1
Brandner, S; Heinz, G; Karl, M; Lerch, C; Pichler, P; Renner, B; Stadlbauer, A1
Chen, H; Guo, J; Mao, Y; Ren, G; Tang, C; Tang, WJ; Wang, Y; Wu, JS; Yao, CJ; Yao, Y; Zhou, LF; Zhuang, DX1
Cooper, LA; Cordova, JS; Gurbani, SS; Hadjipanayis, CG; Holder, CA; Kairdolf, B; Liang, Z; Neill, SG; Olson, JJ; Schreibmann, E; Shim, H; Shu, HK1
Bulik, M; Jancalek, R; Kazda, T; Lakomy, R; Pospisil, P; Slampa, P; Smrcka, M1
Carro, MS; Heiland, DH; Lange, T; Mader, I; Pfeifer, D; Schlosser, P; Schwarzwald, R; Urbach, H; Vasilikos, I; Weyerbrock, A1
Butowski, N; Cha, S; Chang, SM; Clarke, J; Crane, JC; Li, Y; Lupo, JM; Molinaro, A; Nelson, SJ; Olson, M; Prados, M; Roy, R1
Boonzaier, NR; Larkin, TJ; Matys, T; Price, SJ; van der Hoorn, A; Yan, JL1
Berger, MS; Cha, S; Chang, SM; Crawford, FW; Khayal, IS; Lamborn, KR; McGue, C; Nelson, SJ; Pirzkall, A; Saraswathy, S1
Celda, B; Martínez-Bisbal, MC1
Eloqayli, H; Haukvik, A; Melø, TM; Sonnewald, U1
Bangert, B; Cohen, M; Colussi, V; Einstein, DB; Fu, P; Lewin, J; Maciunas, R; Nelson, AD; Sagar, S; Sloan, A; Vinkler, R; Wessels, B; Williams, J; Zheng, Y1
Boockvar, JA; Christos, P; Jeon, JY; K Burkhardt, J; Kesavabhotla, K; Kovanlikaya, I; Mao, X; Riina, H; Shin, B; Shungu, DC; Tsiouris, AJ1
Agildere, M; Aslan, H; Coban, G; Donmez, FY; Ozen, O1
Fezoulidis, I; Fountas, K; Kapsalaki, E; Kousi, E; Svolos, P; Theodorou, K; Tsougos, I1
Gmeiner, M; Sonnberger, M; Weis, S; Wurm, G1
Harada, M; Kageji, T; Nagahiro, S; Nakaiso, M; Takimoto, O; Uno, M1
Barton, SJ; Bell, BA; Cudlip, SA; Doyle, VL; Griffiths, JR; Howe, FA; McLean, MA; Murphy, M; Opstad, KS; Saunders, DE; Stubbs, M; Wilkins, P1
Bulakbasi, N; Kocaoglu, M; Ors, F; Tayfun, C; Uçöz, T1
Catalaa, I; Chang, S; Dillon, WP; Henry, RG; Li, X; Lu, Y; Nelson, SJ; Oh, J; Pirzkall, A1
Chan, AA; Chang, SM; Dillon, WP; Larson, D; Lau, A; McDermott, MW; Nelson, SJ; Pirzkall, A; Verhey, LJ1
Godfrey, W; Hu, J; Magalhaes, A; Shen, Y; Smith, W1
Häkkinen, AM; Hiltunen, Y; Kauppinen, RA; Lundbom, N; Paetau, A; Pulkkinen, J1
Belan, V; Béres, A; De Riggo, J; Dobrota, D; Galanda, M; Likavcanová, K; Liptaj, T; Mlynárik, V; Prónayová, N1
Bachert, P; Debus, J; Hamprecht, F; Kauczor, HU; Lichy, MP; Schlemmer, HP; Schulz-Ertner, D; Weber, MA1
Aragão, Mde F; Araújo, N; Azevedo Filho, HR; Leite, Cda C; Melo, RV; Otaduy, MC; Silva, JL; Valença, MM; Victor, EG1
Bachaud, JM; Berchery, D; Berry, I; Cassol, E; Catalaa, I; Laprie, A; Marre, D; McKnight, TR; Moyal, EC1
Burlina, AP; Hagberg, G; Mader, I; Radue, EW; Roser, W; Seelig, J1
Booth, RA; Buchthal, S; Chang, L; Chiang, F; McBride, DQ; Miller, BL; Nikas, DL1
Lai, PH; Lazeyras, F; Smith, JS; Tien, RD1
Chang, S; Day, MR; Dillon, WP; Gutin, PH; Henry, RG; Huhn, SL; Larson, DA; McDermott, M; Nelson, SJ; Noworolski, SE; Prados, MD; Sneed, PK; Vigneron, DB; Wald, LL; Wara, WM1
Asari, S; Itoh, T; Kinoshita, K; Matsumoto, K; Ohmoto, T; Tada, E1
Baunach, S; Gerlach, M; Lan, J; Meixensberger, J; Roosen, K1
Dunn, JF; Mamourian, A; Meyerand, ME; Pipas, JM; Tosteson, TD1
Arnold, DL; Caramanos, Z; Langleben, A; LeBlanc, R; Preul, MC; Shenouda, G; Villemure, JG1
Chang, S; Chin, C; Dillon, WP; Graves, EE; Lamborn, K; Larson, D; McDermott, M; Nelson, SJ; Prados, MD; Sneed, PK; Verhey, L; Vigneron, DB1
Coons, SW; Heiserman, JE; Keller, PJ; Pitt, A; Ricci, PE1
Castillo, M; Kwock, L; Smith, JK1
Fountas, KN; Gotsis, SD; Johnston, KW; Kapsalaki, EZ; Kapsalakis, JZ; Papadakis, N; Robinson, JS; Smisson , HF1
Baik, HM; Choe, BY; Choi, BG; Kang, JK; Kim, EN; Kim, MC; Naruse, S; Son, BC1
Kadota, O; Kikuchi, K; Kohno, K; Kumon, Y; Miki, H; Ohue, S; Sakaki, S1
Hall, WA; Liu, H; Martin, AJ; Truwit, CL1
Hayashi, K; Ishimaru, H; Iwanaga, S; Kaminogo, M; Morikawa, M; Ochi, M1
Bernsen, HJ; Grotenhuis, JA; Heerschap, A; Meyer, J; Poels, EF; Prick, MJ; van der Kogel, AJ; van Vaals, JJ1
Promyslov, MS1
Cooper, JR; Nadler, JV1
Fischer, W; Müller, E1

Reviews

4 review(s) available for aspartic acid and Astrocytoma, Grade IV

ArticleYear
Progressive multifocal exophytic pontine glioblastoma: a case report with literature review.
    Chinese journal of cancer, 2017, Mar-27, Volume: 36, Issue:1

    Topics: Aspartic Acid; Brain Stem Neoplasms; Child, Preschool; Choline; Diagnosis, Differential; Fatal Outcome; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Multimodal Imaging; Positron Emission Tomography Computed Tomography

2017
Proton magnetic resonance spectroscopy imaging in the study of human brain cancer.
    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2009, Volume: 53, Issue:6

    Topics: Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Glioblastoma; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Multiple Sclerosis; Necrosis; Positron-Emission Tomography; Protons

2009
Glioblastoma with the appearance of arteriovenous malformation: pitfalls in diagnosis.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:5

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Neoplasms; Child; Choline; Diagnosis, Differential; Female; Glioblastoma; Humans; Image Processing, Computer-Assisted; Intracranial Arteriovenous Malformations; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuronavigation; Neurosurgical Procedures; Tomography, X-Ray Computed

2013
Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:2

    Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Energy Metabolism; Glioblastoma; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Necrosis; Neoplasm Invasiveness; Neoplasm Transplantation; Phosphocreatine; Rats; Rats, Nude; Skin Neoplasms; Transplantation, Heterologous

1992

Trials

6 trial(s) available for aspartic acid and Astrocytoma, Grade IV

ArticleYear
Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677.
    Neuro-oncology, 2013, Volume: 15, Issue:7

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Choline; Creatine; Dacarbazine; Feasibility Studies; Follow-Up Studies; Glioblastoma; Humans; Irinotecan; Magnetic Resonance Spectroscopy; Neoplasm Recurrence, Local; Neovascularization, Pathologic; Prognosis; Prospective Studies; Survival Rate; Temozolomide

2013
Evaluation of the lactate-to-N-acetyl-aspartate ratio defined with magnetic resonance spectroscopic imaging before radiation therapy as a new predictive marker of the site of relapse in patients with glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2014, Oct-01, Volume: 90, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Creatine; Female; Glioblastoma; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Quinolones; Radiotherapy, Conformal; Sensitivity and Specificity

2014
Phase II trial of radiosurgery to magnetic resonance spectroscopy-defined high-risk tumor volumes in patients with glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2012, Nov-01, Volume: 84, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Choline; Combined Modality Therapy; Feasibility Studies; Female; Glioblastoma; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Radiosurgery; Radiotherapy, Conformal; Tumor Burden; Young Adult

2012
Metabolic response of glioblastoma to superselective intra-arterial cerebral infusion of bevacizumab: a proton MR spectroscopic imaging study.
    AJNR. American journal of neuroradiology, 2012, Volume: 33, Issue:11

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Aspartic Acid; Bevacizumab; Brain; Brain Neoplasms; Cerebral Arteries; Choline; Female; Glioblastoma; Humans; Infusions, Intra-Arterial; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Treatment Outcome

2012
[Multivoxel spectroscopy with short echo time: choline/N-acetyl-aspartate ratio and the grading of cerebral astrocytomas].
    Arquivos de neuro-psiquiatria, 2007, Volume: 65, Issue:2A

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain Neoplasms; Child; Choline; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Invasiveness; Prospective Studies; Protons; Sensitivity and Specificity; Time Factors

2007
Proton magnetic resonance spectroscopic imaging in newly diagnosed glioblastoma: predictive value for the site of postradiotherapy relapse in a prospective longitudinal study.
    International journal of radiation oncology, biology, physics, 2008, Mar-01, Volume: 70, Issue:3

    Topics: Adult; Aspartic Acid; Brain Neoplasms; Choline; Female; Glioblastoma; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Predictive Value of Tests; Prospective Studies; Protons

2008

Other Studies

50 other study(ies) available for aspartic acid and Astrocytoma, Grade IV

ArticleYear
N-acetyl l-aspartate and Triacetin modulate tumor suppressor MicroRNA and class I and II HDAC gene expression induce apoptosis in Glioblastoma cancer cells in vitro.
    Life sciences, 2021, Dec-01, Volume: 286

    Topics: Apoptosis; Aspartic Acid; Brain Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioblastoma; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; MicroRNAs; Triacetin; Tumor Cells, Cultured

2021
Quantitative measurement of peritumoral concentrations of glutamate, N-acetyl aspartate, and lactate on magnetic resonance spectroscopy predicts glioblastoma-related refractory epilepsy.
    Acta neurochirurgica, 2022, Volume: 164, Issue:12

    Topics: Aspartic Acid; Creatine; Drug Resistant Epilepsy; Epilepsy, Temporal Lobe; Glioblastoma; Glutamic Acid; Humans; Lactic Acid; Magnetic Resonance Spectroscopy

2022
Is pre-radiotherapy metabolic heterogeneity of glioblastoma predictive of progression-free survival?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 183

    Topics: Aspartic Acid; Brain Neoplasms; Choline; Glioblastoma; Humans; Lactates; Magnetic Resonance Imaging; Progression-Free Survival; Prospective Studies

2023
Correlations between DTI-derived metrics and MRS metabolites in tumour regions of glioblastoma: a pilot study.
    Radiology and oncology, 2020, 09-29, Volume: 54, Issue:4

    Topics: Anisotropy; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Contrast Media; Creatine; Diffusion Tensor Imaging; Gadolinium DTPA; Glioblastoma; Humans; Inositol; Magnetic Resonance Spectroscopy; Pilot Projects; Retrospective Studies

2020
Multimodal MR Features of 8 Cases of Epithelioid Glioblastoma.
    BioMed research international, 2020, Volume: 2020

    Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Cerebrovascular Circulation; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Edema; Epithelioid Cells; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Metastasis

2020
Hyperpolarized
    Scientific reports, 2021, 03-11, Volume: 11, Issue:1

    Topics: Aerobiosis; Animals; Aspartic Acid; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Glioblastoma; Glucose; Glycolysis; Humans; Lactic Acid; Magnetic Resonance Imaging; Metabolomics; Mice, SCID; Pyruvic Acid

2021
Altered function of the glutamate-aspartate transporter GLAST, a potential therapeutic target in glioblastoma.
    International journal of cancer, 2019, 05-15, Volume: 144, Issue:10

    Topics: Amino Acid Transport System X-AG; Animals; Apoptosis; Aspartic Acid; Astrocytes; Benzopyrans; Cell Line, Tumor; Cell Membrane; Excitatory Amino Acid Transporter 1; Female; Glioblastoma; Glioma; Glutamic Acid; Humans; Mice; Mice, Inbred C57BL; Protein Transport; Sodium-Potassium-Exchanging ATPase

2019
Incorporation of a spectral model in a convolutional neural network for accelerated spectral fitting.
    Magnetic resonance in medicine, 2019, Volume: 81, Issue:5

    Topics: Algorithms; Artifacts; Aspartic Acid; Brain Mapping; Brain Neoplasms; Choline; Computer Graphics; Creatine; Databases, Factual; Deep Learning; Echo-Planar Imaging; Glioblastoma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Models, Theoretical; Neural Networks, Computer; Signal-To-Noise Ratio; Software; User-Computer Interface; White Matter

2019
Reversing chemoresistance of malignant glioma stem cells using gold nanoparticles.
    International journal of nanomedicine, 2013, Volume: 8

    Topics: Analysis of Variance; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspartic Acid; Cell Survival; Cells, Cultured; Dacarbazine; Drug Delivery Systems; Drug Resistance, Neoplasm; Drug Stability; Drug Synergism; Flow Cytometry; Glioblastoma; Gold; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Neoplastic Stem Cells; Temozolomide

2013
3-Dimensional magnetic resonance spectroscopic imaging at 3 Tesla for early response assessment of glioblastoma patients during external beam radiation therapy.
    International journal of radiation oncology, biology, physics, 2014, Sep-01, Volume: 90, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Chemoradiotherapy; Choline; Contrast Media; Dacarbazine; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Gadolinium; Glioblastoma; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Neoplasm Recurrence, Local; Proportional Hazards Models; Radiotherapy Dosage; Temozolomide; Time Factors

2014
Volumetric spectroscopic imaging of glioblastoma multiforme radiation treatment volumes.
    International journal of radiation oncology, biology, physics, 2014, Oct-01, Volume: 90, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Brain; Brain Edema; Brain Mapping; Brain Neoplasms; Choline; Creatine; Female; Glioblastoma; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Retrospective Studies; Tumor Burden

2014
Quantification of serial changes in cerebral blood volume and metabolism in patients with recurrent glioblastoma undergoing antiangiogenic therapy.
    European journal of radiology, 2015, Volume: 84, Issue:6

    Topics: Angiogenesis Inhibitors; Aspartic Acid; Bevacizumab; Blood Volume; Brain; Brain Mapping; Brain Neoplasms; Cerebrovascular Circulation; Choline; Contrast Media; Female; Follow-Up Studies; Glioblastoma; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Reproducibility of Results

2015
Gene mutation profiling of primary glioblastoma through multiple tumor biopsy guided by 1H-magnetic resonance spectroscopy.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Codon, Nonsense; DNA Mutational Analysis; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Glioblastoma; Humans; Image-Guided Biopsy; Magnetic Resonance Imaging; Male; Middle Aged; Mutation, Missense; Neoplasm Grading; Phenotype; Proton Magnetic Resonance Spectroscopy; Young Adult

2015
Whole-brain spectroscopic MRI biomarkers identify infiltrating margins in glioblastoma patients.
    Neuro-oncology, 2016, Volume: 18, Issue:8

    Topics: Aminolevulinic Acid; Aspartic Acid; Biomarkers; Brain; Brain Neoplasms; Cell Count; Choline; Disease-Free Survival; Glioblastoma; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Neuronavigation; Optical Imaging; Photosensitizing Agents; Proton Magnetic Resonance Spectroscopy; Risk Factors; SOXB1 Transcription Factors

2016
Advanced MRI increases the diagnostic accuracy of recurrent glioblastoma: Single institution thresholds and validation of MR spectroscopy and diffusion weighted MR imaging.
    NeuroImage. Clinical, 2016, Volume: 11

    Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Cohort Studies; Diffusion Magnetic Resonance Imaging; Female; Glioblastoma; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; ROC Curve; Statistics, Nonparametric

2016
Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme.
    Scientific reports, 2016, 06-28, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Neoplasms; Computational Biology; Creatine; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Glioblastoma; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Proteins; Neurons; Oligodendroglia; Prognosis; Prospective Studies; Survival Analysis

2016
Serial analysis of 3D H-1 MRSI for patients with newly diagnosed GBM treated with combination therapy that includes bevacizumab.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Immunological; Aspartic Acid; Bevacizumab; Brain Neoplasms; Choline; Creatine; Dacarbazine; Female; Glioblastoma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Proton Therapy; Statistics, Nonparametric; Temozolomide; Young Adult

2016
Multiparametric MR Imaging of Diffusion and Perfusion in Contrast-enhancing and Nonenhancing Components in Patients with Glioblastoma.
    Radiology, 2017, Volume: 284, Issue:1

    Topics: Adult; Aged; Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Contrast Media; Diffusion Tensor Imaging; Disease Progression; Female; Glioblastoma; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Grading; Organometallic Compounds; Prospective Studies; Retrospective Studies

2017
Relationship of pre-surgery metabolic and physiological MR imaging parameters to survival for patients with untreated GBM.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Brain Mapping; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glioblastoma; Humans; Image Enhancement; Image Processing, Computer-Assisted; Kaplan-Meier Estimate; Lactic Acid; Lipids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Radionuclide Imaging; Retrospective Studies

2009
[2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells.
    Neurochemical research, 2011, Volume: 36, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Aspartic Acid; Astrocytes; Brain Neoplasms; Citric Acid Cycle; Diet, Ketogenic; Glioblastoma; Glucose; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Mice; Tumor Cells, Cultured

2011
Multimodal MR imaging findings of a congenital glioblastoma multiforme.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:11

    Topics: Aspartic Acid; Brain; Brain Neoplasms; Female; Glioblastoma; Humans; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Tomography, X-Ray Computed

2012
Differentiation of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy, diffusion and perfusion metrics at 3 T.
    Cancer imaging : the official publication of the International Cancer Imaging Society, 2012, Oct-26, Volume: 12

    Topics: Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glioblastoma; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; ROC Curve

2012
Brain abscess and glioblastoma identified by combined proton magnetic resonance spectroscopy and diffusion-weighted magnetic resonance imaging--two case reports.
    Neurologia medico-chirurgica, 2002, Volume: 42, Issue:8

    Topics: Acetates; Adult; Amino Acids; Aspartic Acid; Brain Abscess; Brain Neoplasms; Diagnosis, Differential; Diffusion; Frontal Lobe; Glioblastoma; Humans; Image Enhancement; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Reference Values

2002
Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy.
    Magnetic resonance in medicine, 2003, Volume: 49, Issue:2

    Topics: Alanine; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Inositol; Lactic Acid; Lipids; Magnetic Resonance Spectroscopy; Meningeal Neoplasms; Meningioma

2003
Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.
    AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glioblastoma; Glioma; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Sensitivity and Specificity; Teratoma; Tuberculoma, Intracranial

2003
Survival analysis in patients with glioblastoma multiforme: predictive value of choline-to-N-acetylaspartate index, apparent diffusion coefficient, and relative cerebral blood volume.
    Journal of magnetic resonance imaging : JMRI, 2004, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Blood Volume; Brain Neoplasms; Choline; Glioblastoma; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Predictive Value of Tests; Protons; Survival Analysis

2004
Proton magnetic resonance spectroscopy imaging in the evaluation of patients undergoing gamma knife surgery for Grade IV glioma.
    Journal of neurosurgery, 2004, Volume: 101, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Mapping; Brain Neoplasms; Choline; Cohort Studies; Combined Modality Therapy; Cranial Irradiation; Creatine; Disease Progression; Energy Metabolism; Female; Glioblastoma; Humans; Image Processing, Computer-Assisted; Lactic Acid; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neuronavigation; Prognosis; Radiosurgery; Reoperation; Risk; Survival Analysis

2004
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
    Academic radiology, 2005, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Female; Glioblastoma; Glioma; Gliosarcoma; Humans; Hydrogen; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Protons

2005
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
    European journal of radiology, 2005, Volume: 56, Issue:2

    Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glioblastoma; Glioma; Humans; Hydrogen; Image Interpretation, Computer-Assisted; Image Processing, Computer-Assisted; Lactic Acid; Lipids; Magnetic Resonance Imaging; Oligodendroglioma; Phosphocreatine

2005
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
    General physiology and biophysics, 2005, Volume: 24, Issue:3

    Topics: Aspartic Acid; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Choline; Chromium; Creatine; Glioblastoma; Glioma; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Neoplasms; Phosphocreatine; Spectrophotometry

2005
[Application of (1)H MR spectroscopic imaging in radiation oncology: choline as a marker for determining the relative probability of tumor progression after radiation of glial brain tumors].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2006, Volume: 178, Issue:6

    Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Choline; Combined Modality Therapy; Contrast Media; Cranial Irradiation; Diagnosis, Differential; Disease Progression; Female; Follow-Up Studies; Gadolinium DTPA; Glioblastoma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Oligodendroglioma; Phosphocreatine; Predictive Value of Tests; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Adjuvant; Reference Values; Stereotaxic Techniques

2006
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
    Magnetic resonance in medicine, 1995, Volume: 34, Issue:2

    Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminant Analysis; Female; Glioblastoma; Glioma; Glutamates; Glutamine; Glycine; Humans; Hydrogen; Inositol; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oligodendroglioma; Protons

1995
Analysis of brain tumors using 1H magnetic resonance spectroscopy.
    Surgical neurology, 1995, Volume: 44, Issue:2

    Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Glioblastoma; Humans; Lactates; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

1995
Single-voxel proton brain spectroscopy exam (PROBE/SV) in patients with primary brain tumors.
    AJR. American journal of roentgenology, 1996, Volume: 167, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Brain Chemistry; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Magnetic Resonance Spectroscopy; Middle Aged

1996
Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy.
    Journal of neurosurgery, 1997, Volume: 87, Issue:4

    Topics: Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Disease Progression; Feasibility Studies; Follow-Up Studies; Glioblastoma; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Necrosis; Neoplasm Recurrence, Local; Neoplasm, Residual; Protons; Radiation Injuries; Radiography, Interventional; Retrospective Studies; Stereotaxic Techniques; Supratentorial Neoplasms; Tomography, X-Ray Computed

1997
Proton MR spectroscopy of delayed cerebral radiation in monkeys and humans after brachytherapy.
    AJNR. American journal of neuroradiology, 1997, Volume: 18, Issue:9

    Topics: Adult; Animals; Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Cranial Irradiation; Creatine; Diagnosis, Differential; Energy Metabolism; Female; Glioblastoma; Humans; Macaca; Magnetic Resonance Spectroscopy; Male; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Phosphocreatine; Radiation Injuries; Radiation Injuries, Experimental

1997
Intraoperative microdialysis and tissue-pO2 measurement in human glioma.
    Acta neurochirurgica. Supplement, 1998, Volume: 71

    Topics: Aspartic Acid; Brain Edema; Brain Neoplasms; Cell Death; Female; Frontal Lobe; Glioblastoma; Glutamic Acid; Humans; Male; Microdialysis; Monitoring, Intraoperative; Oxygen Consumption; Prognosis; Temporal Lobe

1998
Classification of biopsy-confirmed brain tumors using single-voxel MR spectroscopy.
    AJNR. American journal of neuroradiology, 1999, Volume: 20, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Astrocytoma; Biopsy; Body Water; Brain Neoplasms; Choline; Creatine; Female; Glioblastoma; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged

1999
Using proton magnetic resonance spectroscopic imaging to predict in vivo the response of recurrent malignant gliomas to tamoxifen chemotherapy.
    Neurosurgery, 2000, Volume: 46, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents, Hormonal; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Dose-Response Relationship, Drug; Female; Glioblastoma; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Phosphocreatine; Tamoxifen; Treatment Outcome; Tumor Stem Cell Assay

2000
A preliminary study of the prognostic value of proton magnetic resonance spectroscopic imaging in gamma knife radiosurgery of recurrent malignant gliomas.
    Neurosurgery, 2000, Volume: 46, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Choline; Creatine; Female; Glioblastoma; Humans; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Radiosurgery; Survival Rate

2000
Effect of voxel position on single-voxel MR spectroscopy findings.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:2

    Topics: Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glioblastoma; Humans; Lactic Acid; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neoplasm Recurrence, Local; Retrospective Studies; Sensitivity and Specificity

2000
Correlation of myo-inositol levels and grading of cerebral astrocytomas.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Child; Child, Preschool; Choline; Creatine; Female; Glioblastoma; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged

2000
In vivo proton magnetic resonance spectroscopy of brain tumors.
    Stereotactic and functional neurosurgery, 2000, Volume: 74, Issue:2

    Topics: Adult; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Brain; Brain Abscess; Brain Neoplasms; Choline; Creatine; Glioblastoma; Humans; Lactates; Lipid Metabolism; Magnetic Resonance Spectroscopy; Meningioma; Middle Aged; Oligodendroglioma; Phosphocreatine; Reference Values

2000
Proton magnetic resonance chemical shift imaging (1H CSI)-directed stereotactic biopsy.
    Acta neurochirurgica, 2001, Volume: 143, Issue:1

    Topics: Adult; Aspartic Acid; Biopsy, Needle; Brain; Brain Neoplasms; Creatine; Diagnosis, Differential; Energy Metabolism; Female; Glioblastoma; Glioma; Humans; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Necrosis; Phosphocreatine; Phosphorylcholine; Stereotaxic Techniques

2001
Discrimination of brain abscess and cystic tumor by in vivo proton magnetic resonance spectroscopy.
    Neurologia medico-chirurgica, 2001, Volume: 41, Issue:3

    Topics: Acetates; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Bacteria; Biomarkers; Brain Abscess; Child; Choline; Creatine; Cysts; Diagnosis, Differential; Female; Frontal Lobe; Glioblastoma; Humans; Lactates; Lipids; Magnetic Resonance Spectroscopy; Male; Parietal Lobe; Protons; Retrospective Studies; Succinates; Supratentorial Neoplasms

2001
An efficient chemical shift imaging scheme for magnetic resonance-guided neurosurgery.
    Journal of magnetic resonance imaging : JMRI, 2001, Volume: 14, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Biopsy; Brain; Brain Mapping; Brain Neoplasms; Choline; Creatine; Energy Metabolism; Glioblastoma; Humans; Image Enhancement; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neoplasm Recurrence, Local; Phantoms, Imaging; Stereotaxic Techniques

2001
Differentiation between high-grade glioma and metastatic brain tumor using single-voxel proton MR spectroscopy.
    European radiology, 2001, Volume: 11, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Child; Choline; Creatine; Diagnosis, Differential; Female; Glioblastoma; Humans; Lactic Acid; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged

2001
Some biochemical characteristics of neuroglia as deduced by glial tumor biochemical analysis.
    Journal of neurosurgery, 1971, Volume: 34, Issue:3

    Topics: Aminobutyrates; Aspartic Acid; Astrocytoma; Brain; Brain Chemistry; Brain Neoplasms; Carboxy-Lyases; Cerebrosides; Cholesterol; Galactose; Glioblastoma; Hexoses; Histocytochemistry; Humans; In Vitro Techniques; Lipids; Neuroglia; Phospholipids; Transaminases

1971
N-acetyl-L-aspartic acid content of human neural tumours and bovine peripheral nervous tissues.
    Journal of neurochemistry, 1972, Volume: 19, Issue:2

    Topics: Animals; Aspartic Acid; Brain Neoplasms; Cattle; Cerebral Cortex; Craniopharyngioma; Glioblastoma; Glioma; Hemangiosarcoma; Humans; Medulloblastoma; Meningioma; Neoplasms, Nerve Tissue; Neurilemmoma; Oligodendroglioma; Peripheral Nerves; Retina

1972
[Activities of glutamate dehydrogenase and aspartate aminotransferase in human brain tumors].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1972, Volume: 115, Issue:1

    Topics: Adenoma; Aspartate Aminotransferases; Aspartic Acid; Astrocytoma; Biopsy; Brain Neoplasms; Craniopharyngioma; Ependymoma; Glioblastoma; Glutamate Dehydrogenase; Glutamates; Histocytochemistry; Humans; Lipoma; Meningioma; Neurilemmoma; Neurofibroma; Oligodendroglioma; Sarcoma

1972