aspartic acid and Argininosuccinate Synthase Deficiency Disease
aspartic acid has been researched along with Argininosuccinate Synthase Deficiency Disease in 10 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" Here, we show that ASS1 functions as a tumor suppressor in breast cancer, and the pesticide spinosyn A (SPA) and its derivative LM-2I suppress breast tumor cell proliferation and growth by binding to and activating ASS1." | 4.02 | Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor. ( Cao, D; Chen, C; Chen, L; Chen, X; Hu, X; Kong, F; Li, J; Li, X; Liu, O; Liu, S; Luo, J; Luo, T; Luo, W; Luo, Z; Ma, D; Ming, Z; Peng, K; Wen, M; Xia, L; Xie, Y; Xu, N; Yang, C; Yi, W; Zou, Z, 2021) |
"Citrullinemia type 1 is an autosomal-recessive urea cycle disorder caused by mutations in the ASS1 gene and characterised by increased plasma citrulline concentrations." | 3.83 | Kinetic mutations in argininosuccinate synthetase deficiency: characterisation and in vitro correction by substrate supplementation. ( Diez-Fernandez, C; Fingerhut, R; Gemperle, C; Häberle, J; Rüfenacht, V; Wellauer, O, 2016) |
Research
Studies (10)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (40.00) | 29.6817 |
2010's | 3 (30.00) | 24.3611 |
2020's | 3 (30.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Tavoulari, S | 1 |
Lacabanne, D | 1 |
Thangaratnarajah, C | 1 |
Kunji, ERS | 1 |
Yau, WW | 1 |
Chen, GB | 1 |
Zhou, J | 1 |
Francisco, JC | 1 |
Thimmukonda, NK | 1 |
Li, S | 1 |
Singh, BK | 1 |
Yen, PM | 1 |
Zou, Z | 1 |
Hu, X | 1 |
Luo, T | 1 |
Ming, Z | 1 |
Chen, X | 1 |
Xia, L | 1 |
Luo, W | 1 |
Li, J | 1 |
Xu, N | 1 |
Chen, L | 1 |
Cao, D | 1 |
Wen, M | 1 |
Kong, F | 1 |
Peng, K | 1 |
Xie, Y | 1 |
Li, X | 1 |
Ma, D | 1 |
Yang, C | 1 |
Chen, C | 1 |
Yi, W | 1 |
Liu, O | 1 |
Liu, S | 1 |
Luo, J | 1 |
Luo, Z | 1 |
Saheki, T | 4 |
Moriyama, M | 3 |
Kuroda, E | 1 |
Funahashi, A | 1 |
Yasuda, I | 1 |
Setogawa, Y | 1 |
Gao, Q | 1 |
Ushikai, M | 1 |
Furuie, S | 1 |
Yamamura, KI | 1 |
Takano, K | 1 |
Nakamura, Y | 2 |
Eto, K | 1 |
Kadowaki, T | 1 |
Sinasac, DS | 3 |
Furukawa, T | 1 |
Horiuchi, M | 3 |
Tai, YH | 1 |
Rabinovich, S | 1 |
Adler, L | 1 |
Yizhak, K | 1 |
Sarver, A | 1 |
Silberman, A | 1 |
Agron, S | 1 |
Stettner, N | 1 |
Sun, Q | 1 |
Brandis, A | 1 |
Helbling, D | 1 |
Korman, S | 1 |
Itzkovitz, S | 1 |
Dimmock, D | 1 |
Ulitsky, I | 1 |
Nagamani, SC | 1 |
Ruppin, E | 1 |
Erez, A | 1 |
Diez-Fernandez, C | 1 |
Wellauer, O | 1 |
Gemperle, C | 1 |
Rüfenacht, V | 1 |
Fingerhut, R | 1 |
Häberle, J | 1 |
Jalil, MA | 1 |
Begum, L | 1 |
Li, MX | 2 |
Iijima, M | 2 |
Robinson, BH | 1 |
Kobayashi, K | 3 |
Tsui, LC | 2 |
Kannan, Y | 1 |
Tanaka, M | 1 |
Fiermonte, G | 1 |
Soon, D | 1 |
Chaudhuri, A | 1 |
Paradies, E | 1 |
Lee, PJ | 1 |
Krywawych, S | 1 |
Palmieri, F | 1 |
Lachmann, RH | 1 |
Reviews
2 reviews available for aspartic acid and Argininosuccinate Synthase Deficiency Disease
Article | Year |
---|---|
Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency.
Topics: Adult; Aspartic Acid; Calcium; Citrullinemia; Glutamates; Humans; Infant, Newborn; Mitochondrial Mem | 2022 |
[Molecular basis of citrin deficiency].
Topics: Aspartic Acid; Calcium; Calcium-Binding Proteins; Cholestasis, Intrahepatic; Chromosome Mapping; Cit | 2004 |
Other Studies
8 other studies available for aspartic acid and Argininosuccinate Synthase Deficiency Disease
Article | Year |
---|---|
Nicotinamide riboside rescues dysregulated glycolysis and fatty acid β-oxidation in a human hepatic cell model of citrin deficiency.
Topics: Aspartic Acid; Citrullinemia; Fatty Acids; Glycolysis; Hepatocytes; Humans; Hyperammonemia; Malates; | 2023 |
Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor.
Topics: Adult; Aged; Animals; Argininosuccinate Synthase; Aspartic Acid; Breast; Breast Neoplasms; Cell Line | 2021 |
Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.
Topics: Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Citrulline; Citrullinemia; Disease | 2019 |
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.
Topics: Animals; Argininosuccinate Synthase; Aspartate Carbamoyltransferase; Aspartic Acid; Calcium-Binding | 2015 |
Kinetic mutations in argininosuccinate synthetase deficiency: characterisation and in vitro correction by substrate supplementation.
Topics: Argininosuccinate Synthase; Aspartic Acid; Catalytic Domain; Citrulline; Citrullinemia; Humans; Kine | 2016 |
Slc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemia.
Topics: Amino Acids; Ammonia; Animals; Argininosuccinate Synthase; Aspartic Acid; Base Sequence; Citrullinem | 2004 |
Pyruvate ameliorates the defect in ureogenesis from ammonia in citrin-deficient mice.
Topics: Amino Acids; Ammonia; Animals; Anticoagulants; Aspartic Acid; Calcium-Binding Proteins; Citric Acid; | 2006 |
An adult with type 2 citrullinemia presenting in Europe.
Topics: Adult; Aspartic Acid; Biological Transport, Active; Citrullinemia; Europe; Fatal Outcome; Glutamic A | 2008 |