aspartic acid has been researched along with Anxiety in 24 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the same brain region, glutamate+glutamine is lower in methamphetamine users than in controls and is negatively correlated with depression." | 3.91 | N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users. ( Alger, JR; Johnson, MC; London, ED; O'Neill, J; Shen, Z; Tang, J, 2019) |
| " In the present study, we investigated the effect of KNT-127 co-perfusion in the PL-PFC on anxiety-like behavior in mice, induced by a glial glutamate transporter inhibitor, (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-l-aspartic acid (TFB-TBOA)." | 3.88 | A delta opioid receptor agonist, KNT-127, in the prelimbic medial prefrontal cortex attenuates glial glutamate transporter blocker-induced anxiety-like behavior in mice. ( Kayashima, S; Nagase, H; Oka, JI; Saitoh, A; Soda, A; Yamada, M; Yoshizawa, K, 2018) |
| "One of the most striking discoveries in the treatment of major depression was the finding that infusion of a single sub-anesthetic dose of ketamine induces rapid and sustained antidepressant effects in treatment-resistant depressed patients." | 3.83 | Repeated ketamine treatment induces sex-specific behavioral and neurochemical effects in mice. ( Mauch, J; Pandit, R; Pitychoutis, PM; Sens, J; Thelen, C, 2016) |
| "Impaired function of the central gamma-aminobutyric acid (GABA) system, which provides the brain's major inhibitory pathways, is thought to play an important role in the pathophysiology of anxiety disorders." | 3.76 | Effect of acute psychological stress on prefrontal GABA concentration determined by proton magnetic resonance spectroscopy. ( Drevets, WC; Grillon, C; Hasler, G; Shen, J; van der Veen, JW, 2010) |
| "Nine heavy caffeine users and nine caffeine-intolerant individuals, who had previously discontinued or substantially curtailed use of caffeinated products because of associated anxiety and discomforting physiological arousal, were studied at baseline and then during 1 hour following ingestion of caffeine citrate (10 mg/kg)." | 3.70 | Human brain metabolic response to caffeine and the effects of tolerance. ( Artru, AA; Dager, SR; Friedman, SD; Hayes, CE; Heide, A; Layton, ME; Posse, S; Richards, TL; Strauss, W, 1999) |
| "Ketamine is an anesthetic with antidepressant properties." | 1.42 | The positive effect on ketamine as a priming adjuvant in antidepressant treatment. ( Dalla, C; Ferreira, C; Kokras, N; Melo, A; Pêgo, JM; Sousa, N; Ventura-Silva, AP, 2015) |
| "Patients with mitochondrial disorders offer a unique window through which we can begin to understand the association between psychiatric symptoms and mitochondrial dysfunction in vivo." | 1.38 | Psychiatric symptoms correlate with metabolic indices in the hippocampus and cingulate in patients with mitochondrial disorders. ( Anglin, RE; Mazurek, MF; Noseworthy, MD; Rosebush, PI; Tarnopolsky, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 11 (45.83) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J | 1 |
| Zou, S | 1 |
| Qu, Y | 1 |
| Zhang, C | 1 |
| Zhang, Y | 1 |
| Tang, X | 1 |
| Ren, Y | 1 |
| Zhang, JP | 1 |
| Zhang, KY | 1 |
| Guo, L | 1 |
| Chen, QL | 1 |
| Gao, P | 1 |
| Wang, T | 1 |
| Li, J | 1 |
| Guo, GZ | 1 |
| Ding, GR | 1 |
| Tang, J | 1 |
| O'Neill, J | 1 |
| Alger, JR | 1 |
| Shen, Z | 1 |
| Johnson, MC | 1 |
| London, ED | 1 |
| Saitoh, A | 1 |
| Soda, A | 1 |
| Kayashima, S | 1 |
| Yoshizawa, K | 1 |
| Oka, JI | 1 |
| Nagase, H | 1 |
| Yamada, M | 1 |
| Strasser, A | 1 |
| Xin, L | 1 |
| Gruetter, R | 1 |
| Sandi, C | 1 |
| Liu, T | 1 |
| Li, Z | 1 |
| He, J | 1 |
| Yang, N | 1 |
| Han, D | 1 |
| Li, Y | 1 |
| Tian, X | 1 |
| Liu, H | 1 |
| Manyande, A | 1 |
| Xiang, H | 1 |
| Xu, F | 1 |
| Wang, J | 1 |
| Guo, X | 1 |
| Muelly, ER | 1 |
| Moore, GJ | 1 |
| Bunce, SC | 1 |
| Mack, J | 1 |
| Bigler, DC | 1 |
| Morton, DH | 1 |
| Strauss, KA | 1 |
| Melo, A | 1 |
| Kokras, N | 1 |
| Dalla, C | 1 |
| Ferreira, C | 1 |
| Ventura-Silva, AP | 1 |
| Sousa, N | 1 |
| Pêgo, JM | 1 |
| Thelen, C | 1 |
| Sens, J | 1 |
| Mauch, J | 1 |
| Pandit, R | 1 |
| Pitychoutis, PM | 1 |
| Onaolapo, AY | 1 |
| Onaolapo, OJ | 1 |
| Nwoha, PU | 1 |
| Skórzewska, A | 1 |
| Bidziński, A | 1 |
| Hamed, A | 1 |
| Lehner, M | 1 |
| Turzyńska, D | 1 |
| Sobolewska, A | 1 |
| Szyndler, J | 1 |
| Maciejak, P | 1 |
| Wisłowska-Stanek, A | 1 |
| Płaźnik, A | 1 |
| Hasler, G | 1 |
| van der Veen, JW | 1 |
| Grillon, C | 1 |
| Drevets, WC | 1 |
| Shen, J | 1 |
| Bédard, MJ | 1 |
| Chantal, S | 1 |
| Anglin, RE | 1 |
| Rosebush, PI | 1 |
| Noseworthy, MD | 1 |
| Tarnopolsky, M | 1 |
| Mazurek, MF | 1 |
| Grachev, ID | 5 |
| Fredrickson, BE | 2 |
| Apkarian, AV | 4 |
| Gallinat, J | 1 |
| Ströhle, A | 1 |
| Lang, UE | 1 |
| Bajbouj, M | 1 |
| Kalus, P | 1 |
| Montag, C | 1 |
| Seifert, F | 1 |
| Wernicke, C | 1 |
| Rommelspacher, H | 1 |
| Rinneberg, H | 1 |
| Schubert, F | 1 |
| Dager, SR | 1 |
| Layton, ME | 1 |
| Strauss, W | 1 |
| Richards, TL | 1 |
| Heide, A | 1 |
| Friedman, SD | 1 |
| Artru, AA | 1 |
| Hayes, CE | 1 |
| Posse, S | 1 |
| Stork, O | 1 |
| Ji, FY | 1 |
| Kaneko, K | 1 |
| Stork, S | 1 |
| Yoshinobu, Y | 1 |
| Moriya, T | 1 |
| Shibata, S | 1 |
| Obata, K | 1 |
| Apkarian, VA | 1 |
| Fredickson, BE | 1 |
| Lane, JD | 1 |
| Miyauchi, T | 1 |
| Dworkin, SI | 1 |
| Co, C | 1 |
| Smith, JE | 1 |
1 trial available for aspartic acid and Anxiety
| Article | Year |
|---|---|
Brain chemistry reflects dual states of pain and anxiety in chronic low back pain.
Topics: Adult; Anxiety; Aspartic Acid; Biomarkers; Brain Chemistry; Female; Gyrus Cinguli; Humans; Image Pro | 2002 |
23 other studies available for aspartic acid and Anxiety
| Article | Year |
|---|---|
Neurometabolic alterations in bipolar disorder with anxiety symptoms: A proton magnetic resonance spectroscopy study of the prefrontal whiter matter.
Topics: Anxiety; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Humans; Proton Magnetic Resonance Spect | 2021 |
Effects of 1.8 GHz Radiofrequency Fields on the Emotional Behavior and Spatial Memory of Adolescent Mice.
Topics: Animals; Anxiety; Aspartic Acid; Behavior, Animal; Cell Phone Use; Cerebral Cortex; gamma-Aminobutyr | 2017 |
N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Anxiety; Aspartic Acid; Central Nervous System Sti | 2019 |
A delta opioid receptor agonist, KNT-127, in the prelimbic medial prefrontal cortex attenuates glial glutamate transporter blocker-induced anxiety-like behavior in mice.
Topics: Amino Acid Transport System X-AG; Animals; Anti-Anxiety Agents; Anxiety; Aspartic Acid; Drug Interac | 2018 |
Nucleus accumbens neurochemistry in human anxiety: A 7 T
Topics: Adult; Anxiety; Aspartic Acid; Correlation of Data; Female; gamma-Aminobutyric Acid; Glutamic Acid; | 2019 |
Regional Metabolic Patterns of Abnormal Postoperative Behavioral Performance in Aged Mice Assessed by
Topics: Aging; Anesthesia; Animals; Anxiety; Aspartic Acid; Brain; Cerebral Cortex; Cognitive Dysfunction; F | 2020 |
Biochemical correlates of neuropsychiatric illness in maple syrup urine disease.
Topics: Adolescent; Adult; Affect; Anxiety; Aspartic Acid; Attention; Brain; Case-Control Studies; Child; Ch | 2013 |
The positive effect on ketamine as a priming adjuvant in antidepressant treatment.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Depression; Depress | 2015 |
Repeated ketamine treatment induces sex-specific behavioral and neurochemical effects in mice.
Topics: Animals; Antidepressive Agents; Anxiety; Aspartic Acid; Depression; Female; Glutamic Acid; Hippocamp | 2016 |
Aspartame and the hippocampus: Revealing a bi-directional, dose/time-dependent behavioural and morphological shift in mice.
Topics: Animals; Anxiety; Aspartame; Aspartic Acid; Astrocytes; Behavior, Animal; Cell Count; Dose-Response | 2017 |
The effect of CRF and alpha-helical CRF((9-41)) on rat fear responses and amino acids release in the central nucleus of the amygdala.
Topics: Amino Acids; Amygdala; Animals; Anxiety; Aspartic Acid; Conditioning, Classical; Corticotropin-Relea | 2009 |
Effect of acute psychological stress on prefrontal GABA concentration determined by proton magnetic resonance spectroscopy.
Topics: Acute Disease; Adult; Animals; Anxiety; Anxiety Disorders; Aspartic Acid; Choline; Diagnostic and St | 2010 |
Brain magnetic resonance spectroscopy in obsessive-compulsive disorder: the importance of considering subclinical symptoms of anxiety and depression.
Topics: Adult; Anxiety; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Depression; Female; Function | 2011 |
Psychiatric symptoms correlate with metabolic indices in the hippocampus and cingulate in patients with mitochondrial disorders.
Topics: Adult; Aged; Anxiety; Aspartic Acid; Case-Control Studies; Caudate Nucleus; Creatine; Female; Glutam | 2012 |
Association of human hippocampal neurochemistry, serotonin transporter genetic variation, and anxiety.
Topics: Alleles; Anxiety; Aspartic Acid; Biomarkers; DNA; Genotype; Gyrus Cinguli; Hippocampus; Humans; Magn | 2005 |
Human brain metabolic response to caffeine and the effects of tolerance.
Topics: Adult; Anxiety; Arousal; Aspartic Acid; Brain; Caffeine; Citrates; Coffee; Drug Combinations; Echo-P | 1999 |
Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65.
Topics: Age Factors; Aggression; Animals; Anxiety; Aspartic Acid; Brain; Brain Chemistry; Circadian Rhythm; | 2000 |
Anxiety in healthy humans is associated with orbital frontal chemistry.
Topics: Adult; Analysis of Variance; Anxiety; Aspartic Acid; Choline; Creatinine; Female; Frontal Lobe; gamm | 2000 |
Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Anxiety; Aspartic Acid; Back Pain; Brain Chemistry; Choline; Chronic Disease; Creatine; Femal | 2000 |
Chemical mapping of anxiety in the brain of healthy humans: an in vivo 1H-MRS study on the effects of sex, age, and brain region.
Topics: Adult; Aging; Anxiety; Aspartic Acid; Brain; Brain Chemistry; Female; Frontal Lobe; Humans; Magnetic | 2000 |
Dissociating anxiety from pain: mapping the neuronal marker N-acetyl aspartate to perception distinguishes closely interrelated characteristics of chronic pain.
Topics: Anxiety; Aspartic Acid; Brain Chemistry; Brain Mapping; Chronic Disease; Humans; Neurons; Pain | 2001 |
Neurochemical changes associated with the action of acute administration of diazepam in reversing the behavioral paradigm conditioned emotional response (CER).
Topics: Amino Acids; Animals; Anxiety; Aspartic Acid; Behavior, Animal; Biogenic Monoamines; Brain; Conditio | 1992 |
Specific effects of punishment on amino acids turnover in discrete rat brain regions.
Topics: Amino Acids; Animals; Anxiety; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Conflict, Ps | 1988 |