aspartic acid has been researched along with Anxiety Disorders in 17 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Anxiety Disorders: Persistent and disabling ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Impaired function of the central gamma-aminobutyric acid (GABA) system, which provides the brain's major inhibitory pathways, is thought to play an important role in the pathophysiology of anxiety disorders." | 3.76 | Effect of acute psychological stress on prefrontal GABA concentration determined by proton magnetic resonance spectroscopy. ( Drevets, WC; Grillon, C; Hasler, G; Shen, J; van der Veen, JW, 2010) |
| "Symptoms of GAD overlap with those of major depressive disorder to such an extent that studying one disorder without studying the other may be impossible." | 2.45 | Neurobiology of generalized anxiety disorder. ( Stein, MB, 2009) |
| "Overweight was associated with reduced NAA concentrations in the hippocampus with a strong effect size." | 1.40 | Reduced hippocampal N-acetyl-aspartate (NAA) as a biomarker for overweight. ( Abdallah, CG; Coplan, JD; Fathy, HM; Kral, JG; Mao, X; Mathew, SJ; Ragab, SA; Shungu, DC, 2014) |
| "7 year; 4 females) received 12 weeks of open-label paroxetine treatment, flexibly dosed up to 60 mg/day." | 1.36 | A pilot study of the effects of chronic paroxetine administration on hippocampal N-acetylaspartate in generalized anxiety disorder. ( Amiel, JM; Coplan, JD; Mao, X; Mathew, SJ; Price, RB; Shungu, DC; Smith, EL, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 13 (76.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strawn, JR | 1 |
| Chu, WJ | 1 |
| Whitsel, RM | 1 |
| Weber, WA | 1 |
| Norris, MM | 1 |
| Adler, CM | 1 |
| Eliassen, JC | 1 |
| Phan, KL | 1 |
| Strakowski, SM | 1 |
| DelBello, MP | 1 |
| Coplan, JD | 7 |
| Fathy, HM | 1 |
| Abdallah, CG | 4 |
| Ragab, SA | 1 |
| Kral, JG | 1 |
| Mao, X | 7 |
| Shungu, DC | 7 |
| Mathew, SJ | 7 |
| Howells, FM | 1 |
| Hattingh, CJ | 1 |
| Syal, S | 1 |
| Breet, E | 1 |
| Stein, DJ | 1 |
| Lochner, C | 1 |
| Moon, CM | 3 |
| Kang, HK | 1 |
| Jeong, GW | 3 |
| Raparia, E | 1 |
| Hof, PR | 1 |
| Cordero, MI | 1 |
| Just, N | 1 |
| Poirier, GL | 1 |
| Sandi, C | 1 |
| Sundaram, T | 1 |
| Choi, NG | 1 |
| Price, RB | 2 |
| Smith, EL | 3 |
| Amiel, JM | 1 |
| Stein, MB | 1 |
| Hasler, G | 1 |
| van der Veen, JW | 1 |
| Grillon, C | 1 |
| Drevets, WC | 1 |
| Shen, J | 1 |
| Jackowski, A | 2 |
| Sato, JR | 2 |
| Yue, Q | 1 |
| Liu, M | 1 |
| Nie, X | 1 |
| Wu, Q | 1 |
| Li, J | 1 |
| Zhang, W | 1 |
| Huang, X | 1 |
| Gong, Q | 1 |
| Sackeim, HA | 1 |
| Gorman, JM | 1 |
| Charney, DS | 1 |
| Grachev, ID | 1 |
| Thomas, PS | 1 |
| Ramachandran, TS | 1 |
1 review available for aspartic acid and Anxiety Disorders
| Article | Year |
|---|---|
Neurobiology of generalized anxiety disorder.
Topics: Anxiety Disorders; Aspartic Acid; Brain; Cognition; Comorbidity; Creatine; Depressive Disorder, Majo | 2009 |
2 trials available for aspartic acid and Anxiety Disorders
| Article | Year |
|---|---|
Riluzole effect on occipital cortex: a structural and spectroscopy pilot study.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Aspartic Acid; Excitatory Amino Acid Antagonists; Fem | 2012 |
Hippocampal N-acetylaspartate concentration and response to riluzole in generalized anxiety disorder.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Aspartic Acid; Excitatory Amino Acid Antagonists; Fem | 2008 |
14 other studies available for aspartic acid and Anxiety Disorders
| Article | Year |
|---|---|
A pilot study of anterior cingulate cortex neurochemistry in adolescents with generalized anxiety disorder.
Topics: Adolescent; Anxiety Disorders; Aspartic Acid; Brain Chemistry; Case-Control Studies; Child; Creatine | 2013 |
Reduced hippocampal N-acetyl-aspartate (NAA) as a biomarker for overweight.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Biomarkers; Down-Regulation; Female; Hippocampus; Humans; M | 2014 |
(1)H-magnetic resonance spectroscopy in social anxiety disorder.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Creatine; Dipeptides; Female; Gyrus Cinguli; Humans; Male; | 2015 |
Metabolic change in the right dorsolateral prefrontal cortex and its correlation with symptom severity in patients with generalized anxiety disorder: Proton magnetic resonance spectroscopy at 3 Tesla.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Case-Control Studies; Choline; Creatine; Female; Gray Matte | 2015 |
Impact of childhood emotional abuse on neocortical neurometabolites and complex emotional processing in patients with generalized anxiety disorder.
Topics: Adult; Adult Survivors of Child Abuse; Anxiety Disorders; Aspartic Acid; Case-Control Studies; Choli | 2016 |
Brain morphological alterations and cellular metabolic changes in patients with generalized anxiety disorder: A combined DARTEL-based VBM and (1)H-MRS study.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Female; Fro | 2016 |
Effects of paternal and peripubertal stress on aggression, anxiety, and metabolic alterations in the lateral septum.
Topics: Age Factors; Aggression; Animals; Animals, Newborn; Anxiety Disorders; Aspartic Acid; Creatine; Dise | 2016 |
Working memory dysfunction associated with brain functional deficits and cellular metabolic changes in patients with generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Creati | 2016 |
A pilot study of the effects of chronic paroxetine administration on hippocampal N-acetylaspartate in generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Creatine; Female; Hippocampus; Humans; Male; Middle Aged; N | 2010 |
Effect of acute psychological stress on prefrontal GABA concentration determined by proton magnetic resonance spectroscopy.
Topics: Acute Disease; Adult; Animals; Anxiety; Anxiety Disorders; Aspartic Acid; Choline; Diagnostic and St | 2010 |
A pilot study of hippocampal volume and N-acetylaspartate (NAA) as response biomarkers in riluzole-treated patients with GAD.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Biomarkers; Female; Hippocampus; Humans; Male; Organ Size; | 2013 |
Quantitative 3.0T MR spectroscopy reveals decreased creatine concentration in the dorsolateral prefrontal cortex of patients with social anxiety disorder.
Topics: Anxiety Disorders; Aspartic Acid; Creatine; Energy Metabolism; Female; Functional Laterality; Humans | 2012 |
Dorsolateral prefrontal cortical pathology in generalized anxiety disorder: a proton magnetic resonance spectroscopic imaging study.
Topics: Adult; Anxiety Disorders; Aspartic Acid; Biomarkers; Child; Child Abuse; Creatine; Female; Functiona | 2004 |
Decreased levels of N-acetylaspartate in dorsolateral prefrontal cortex in a case of intractable severe sympathetically mediated chronic pain (complex regional pain syndrome, type I).
Topics: Adult; Anxiety Disorders; Aspartic Acid; Chronic Disease; Depressive Disorder, Major; Female; Humans | 2002 |