aspartic acid has been researched along with Amyloid Deposits in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, L; Gao, H; Qian, S; Qing, G; Wang, C; Wang, X; Zhang, X; Zhong, M | 1 |
| Krause, BJ; Kuhla, A; Lindner, T; Müller, L; Power Guerra, N; Rühlmann, C; Stenzel, J; Teipel, S; Vollmar, B | 1 |
| Robertson, DS | 1 |
| Cheglakov, IB; Kozin, SA; Kukharsky, MS; Kulikova, AA; Makarov, AA; Ovchinnikov, RK | 1 |
| Huang, W; Lei, H; Wang, X; Xu, W; Zhan, Y; Zhang, S | 1 |
| Cynis, H; Güttler, BH; Ludwig, HH; Porzel, A; Schilling, S; Seifert, F | 1 |
| Fukuda, H; Izumiyama, N; Murayama, S; Shimizu, T; Shirasawa, T | 1 |
| Anderson, VE; Atwood, CS; Carey, PR; Dong, J; Perry, G; Siedlak, SL; Smith, MA | 1 |
| Jacobsen, H; Künnecke, B; Loetscher, H; Metzger, F; Ozmen, L; Richards, JG; Steiner, G; von Kienlin, M | 1 |
| Cotman, CW; Fonseca, MI; Head, E; Tenner, AJ; Velazquez, P | 1 |
| Benson, MD; Kluve-Beckerman, B; Liepnieks, JJ; Orpiszewski, J; Schormann, N | 1 |
| Mori, H; Ogawara, M; Shimizu, T; Shirasawa, T; Watanabe, A | 1 |
| Kaneko, I; Kubo, T; Morimoto, K | 1 |
1 review(s) available for aspartic acid and Amyloid Deposits
| Article | Year |
|---|---|
Isoaspartate formation and neurodegeneration in Alzheimer's disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Aspartic Acid; Blood Vessels; Brain; Cerebrovascular Circulation; Humans; In Vitro Techniques; Isomerism; Mice; Mice, Knockout; Molecular Sequence Data; Nerve Degeneration; Plaque, Amyloid; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Protein Processing, Post-Translational; tau Proteins | 2000 |
12 other study(ies) available for aspartic acid and Amyloid Deposits
| Article | Year |
|---|---|
Aspartic Acid-Modified Phospholipids Regulate Cell Response and Rescue Memory Deficits in APP/PS1 Transgenic Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain; Disease Models, Animal; Liposomes; Memory Disorders; Mice; Mice, Transgenic; Phospholipids; Plaque, Amyloid; Presenilin-1 | 2022 |
Long-Term Caloric Restriction Attenuates β-Amyloid Neuropathology and Is Accompanied by Autophagy in APPswe/PS1delta9 Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Autophagy; Calcium-Binding Proteins; Caloric Restriction; Cerebral Cortex; Creatine; Disease Models, Animal; Fluorodeoxyglucose F18; Glucose; Hippocampus; Magnetic Resonance Spectroscopy; Maze Learning; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Microfilament Proteins; Neurons; Plaque, Amyloid; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals | 2021 |
Proposed biochemistry of Parkinson's and Alzheimer's diseases.
Topics: Aldehydes; Alzheimer Disease; Aspartic Acid; Betaine; Brain; Disease Progression; Humans; Kynurenine; Lewy Bodies; Models, Biological; Parkinson Disease; Plaque, Amyloid; Pyruvaldehyde; Quinolinic Acid; Treatment Outcome | 2017 |
Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Analysis of Variance; Animals; Aspartic Acid; Disease Models, Animal; Gene Expression Regulation; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Peptide Fragments; Plaque, Amyloid; Presenilin-1 | 2016 |
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA1 Region, Hippocampal; Creatine; Disease Models, Animal; Down-Regulation; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Nerve Degeneration; Plaque, Amyloid; Presenilin-1; Pyramidal Cells; Thiazoles | 2010 |
A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues.
Topics: Alzheimer Disease; Amino Acid Motifs; Amino Acid Sequence; Amyloid beta-Peptides; Asparagine; Aspartic Acid; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Isoaspartic Acid; Isomerism; Kinetics; Plaque, Amyloid; Protein Processing, Post-Translational | 2013 |
Isoaspartate formation at position 23 of amyloid beta peptide enhanced fibril formation and deposited onto senile plaques and vascular amyloids in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Aspartic Acid; Blood Vessels; Brain; Female; Humans; Immunohistochemistry; Isomerism; Male; Microscopy, Electron; Molecular Structure; Neurofibrillary Tangles; Plaque, Amyloid | 2002 |
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aspartic Acid; Binding Sites; Brain Chemistry; Cerebral Cortex; Copper; Female; Glutamic Acid; Humans; Iron; Metals, Heavy; Methionine; Microscopy; Oxidation-Reduction; Plaque, Amyloid; Protein Structure, Secondary; Spectrum Analysis, Raman; Tyrosine; Zinc | 2003 |
Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Biomarkers; Disease Models, Animal; Disease Progression; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Magnetic Resonance Imaging; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid; Presenilin-2; Spectrum Analysis | 2005 |
The presence of isoaspartic acid in beta-amyloid plaques indicates plaque age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Antibodies; Aspartic Acid; Autopsy; Biomarkers; Brain; Down Syndrome; Entorhinal Cortex; Female; Frontal Lobe; Humans; Immunohistochemistry; Male; Mental Status Schedule; Middle Aged; Organ Specificity; Plaque, Amyloid; Regression Analysis | 1999 |
Protein aging hypothesis of Alzheimer disease.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Aspartic Acid; Biopolymers; Cyclization; Humans; Isomerism; Models, Biological; Models, Molecular; Molecular Sequence Data; Plaque, Amyloid; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Solubility; Succinimides; Thermodynamics; Time Factors | 2000 |
Drastic neuronal loss in vivo by beta-amyloid racemized at Ser(26) residue: conversion of non-toxic [D-Ser(26)]beta-amyloid 1-40 to toxic and proteinase-resistant fragments.
Topics: Alzheimer Disease; Amino Acid Isomerases; Amino Acid Sequence; Aminopeptidases; Amyloid beta-Peptides; Animals; Aspartic Acid; Chymotrypsin; Coloring Agents; Endopeptidases; Excitatory Amino Acid Agonists; Hippocampus; Ibotenic Acid; Male; Nerve Degeneration; Neurofibrillary Tangles; Neurons; PC12 Cells; Peptide Fragments; Plaque, Amyloid; Rats; Rats, Sprague-Dawley; Serine | 2001 |