Page last updated: 2024-11-08

aspartic acid and Amphetamine-Related Disorders

aspartic acid has been researched along with Amphetamine-Related Disorders in 17 studies

Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.

Amphetamine-Related Disorders: Disorders related or resulting from use of amphetamines.

Research Excerpts

ExcerptRelevanceReference
" In the same brain region, glutamate+glutamine is lower in methamphetamine users than in controls and is negatively correlated with depression."3.91N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users. ( Alger, JR; Johnson, MC; London, ED; O'Neill, J; Shen, Z; Tang, J, 2019)
" Because findings from the animal literature have indicated that specific dosage regimens of MDMA can produce long-lasting alterations in serotonergic function, existing studies of MDMA effects in humans have examined brain serotonin (5-HT) transporters (5-HTT) and receptors or have examined brain structures or functions potentially affected by MDMA."2.44Neuroimaging research in human MDMA users: a review. ( Cowan, RL, 2007)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (41.18)29.6817
2010's10 (58.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Toriumi, K1
Tanaka, J1
Mamiya, T1
Alkam, T1
Kim, HC1
Nitta, A1
Nabeshima, T1
Burger, A1
Brooks, SJ1
Stein, DJ2
Howells, FM1
Tang, J1
O'Neill, J1
Alger, JR1
Shen, Z1
Johnson, MC1
London, ED1
Sung, YH3
Carey, PD1
Ferrett, HL1
Spottiswoode, BS1
Renshaw, PF4
Yurgelun-Todd, DA2
O'Phelan, K1
Ernst, T2
Park, D1
Stenger, A1
Denny, K1
Green, D1
Chang, C1
Chang, L2
Crocker, CE1
Bernier, DC1
Hanstock, CC1
Lakusta, B1
Purdon, SE1
Seres, P1
Tibbo, PG1
Kim, JE1
Kim, GH1
Hwang, J2
Kim, JY1
Kim, B1
Kang, I1
Jeon, S1
Ma, J1
Lyoo, IK3
Yoon, S1
Cowan, RL2
Joers, JM1
Dietrich, MS1
Yoon, SJ1
Kim, HJ1
Kim, TS1
Kim, N2
Lukas, SE1
Salo, R4
Buonocore, MH3
Leamon, M2
Natsuaki, Y2
Waters, C3
Moore, CD3
Galloway, GP3
Nordahl, TE4
Natsuaki, YT1
Leamon, MH1
Possin, K1
Gibson, DR1
Flynn, N1
Pfefferbaum, A1
Spielman, DM1
Adalsteinsson, E1
Sullivan, EV1
Speck, O1
Grob, CS1
Kile, S1
Cho, SC1
Kim, SJ1
Kim, H1
Bae, S1
Chang, KH1
Daniels, M1
Reneman, L1
Majoie, CB1
Schmand, B1
van den Brink, W1
den Heeten, GJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical and Imaging Biomarker Trial of Uridine for Veterans With Suicidal Ideation[NCT03265964]Phase 490 participants (Anticipated)Interventional2018-04-02Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aspartic acid and Amphetamine-Related Disorders

ArticleYear
Neuroimaging research in human MDMA users: a review.
    Psychopharmacology, 2007, Volume: 189, Issue:4

    Topics: Amphetamine-Related Disorders; Aspartic Acid; Attention; Biomedical Research; Brain; Cerebrovascular

2007

Trials

2 trials available for aspartic acid and Amphetamine-Related Disorders

ArticleYear
Neurochemical alterations in methamphetamine-dependent patients treated with cytidine-5'-diphosphate choline: a longitudinal proton magnetic resonance spectroscopy study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:5

    Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Central Nervous System Stimulants; Cytidine Dip

2010
Prefrontal N-acetylaspartate is strongly associated with memory performance in (abstinent) ecstasy users: preliminary report.
    Biological psychiatry, 2001, Oct-01, Volume: 50, Issue:7

    Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Humans; Magnetic Resonance Spectroscopy; Male;

2001

Other Studies

14 other studies available for aspartic acid and Amphetamine-Related Disorders

ArticleYear
Shati/Nat8l knockout mice show behavioral deficits ameliorated by atomoxetine and methylphenidate.
    Behavioural brain research, 2018, Feb-26, Volume: 339

    Topics: Acetyltransferases; Amphetamine-Related Disorders; Animals; Aspartic Acid; Atomoxetine Hydrochloride

2018
The impact of acute and short-term methamphetamine abstinence on brain metabolites: A proton magnetic resonance spectroscopy chemical shift imaging study.
    Drug and alcohol dependence, 2018, 04-01, Volume: 185

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dipeptide

2018
N-Acetyl and Glutamatergic Neurometabolites in Perisylvian Brain Regions of Methamphetamine Users.
    The international journal of neuropsychopharmacology, 2019, 01-01, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Anxiety; Aspartic Acid; Central Nervous System Sti

2019
Decreased frontal N-acetylaspartate levels in adolescents concurrently using both methamphetamine and marijuana.
    Behavioural brain research, 2013, Jun-01, Volume: 246

    Topics: Adolescent; Amphetamine-Related Disorders; Analysis of Variance; Aspartic Acid; Brain Mapping; Dipep

2013
Impact of methamphetamine on regional metabolism and cerebral blood flow after traumatic brain injury.
    Neurocritical care, 2013, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Brain Injuries; Central Nerv

2013
Prefrontal glutamate levels differentiate early phase schizophrenia and methamphetamine addiction: a (1)H MRS study at 3Tesla.
    Schizophrenia research, 2014, Volume: 157, Issue:1-3

    Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Glutamic Acid; Humans; Prefrontal C

2014
Metabolic alterations in the anterior cingulate cortex and related cognitive deficits in late adolescent methamphetamine users.
    Addiction biology, 2018, Volume: 23, Issue:1

    Topics: Adolescent; Amphetamine-Related Disorders; Aspartic Acid; Brain; Case-Control Studies; Cognitive Dys

2018
N-acetylaspartate (NAA) correlates inversely with cannabis use in a frontal language processing region of neocortex in MDMA (Ecstasy) polydrug users: a 3 T magnetic resonance spectroscopy study.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 92, Issue:1

    Topics: Amphetamine-Related Disorders; Aspartic Acid; Biomarkers; Brain Chemistry; Female; Hallucinogens; Hu

2009
Extended findings of brain metabolite normalization in MA-dependent subjects across sustained abstinence: a proton MRS study.
    Drug and alcohol dependence, 2011, Jan-15, Volume: 113, Issue:2-3

    Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Female; Gyrus Cinguli

2011
Spatial inhibition and the visual cortex: a magnetic resonance spectroscopy imaging study.
    Neuropsychologia, 2011, Volume: 49, Issue:5

    Topics: Adult; Amphetamine-Related Disorders; Analysis of Variance; Aspartic Acid; Attention; Brain Mapping;

2011
Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine-dependent subjects: a preliminary proton MRS study. Magnetic resonance spectroscopy.
    Psychiatry research, 2002, Nov-30, Volume: 116, Issue:1-2

    Topics: Adult; Age Factors; Amphetamine-Related Disorders; Aspartic Acid; Choline; Creatine; Dopamine; Front

2002
Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities.
    The American journal of psychiatry, 2005, Volume: 162, Issue:2

    Topics: Adult; Amphetamine-Related Disorders; Aspartic Acid; Basal Ganglia; Brain; Brain Diseases; Choline;

2005
Methamphetamine users in sustained abstinence: a proton magnetic resonance spectroscopy study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:4

    Topics: Adult; Ambulatory Care; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dopa

2005
Relationship between N-acetyl-aspartate in gray and white matter of abstinent methamphetamine abusers and their history of drug abuse: a proton magnetic resonance spectroscopy study.
    Drug and alcohol dependence, 2007, Apr-17, Volume: 88, Issue:1

    Topics: Adult; Amphetamine-Related Disorders; Analysis of Variance; Aspartic Acid; Basal Ganglia; Choline; C

2007