Page last updated: 2024-08-17

aspartic acid and Affective Psychosis, Bipolar

aspartic acid has been researched along with Affective Psychosis, Bipolar in 113 studies

Research

Studies (113)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (4.42)	18.7374
1990's	4 (3.54)	18.2507
2000's	55 (48.67)	29.6817
2010's	43 (38.05)	24.3611
2020's	6 (5.31)	2.80

Authors

Authors	Studies
Christensen, G; Fiedorowicz, JG; Harmata, G; Long, JD; Magnotta, VA; Richards, JG; Sathyaputri, L; Shaffer, J; Taylor, E; Wemmie, J; Williams, A; Xu, J	1
Allauze, E; Chabert, J; Chassain, C; De Chazeron, I; Fossati, P; Llorca, PM; Pereira, B; Rotgé, JY; Samalin, L	1
Deep, R; Khandelwal, SK; Kumaran, SS; Mahal, P	1
Chen, F; Chen, G; Huang, H; Jia, Y; Lai, S; Luo, X; Ning, Y; Shan, Y; Shen, S; Wang, Y; Zhang, Y; Zhong, S	1
Brietzke, E; Carmona, NE; Cosgrove, VE; Hajek, T; Iacobucci, M; Kramer, NE; Lee, Y; Mansur, RB; McIntyre, RS; Nasri, F; Newport, J; Pan, Z; Rodrigues, N; Rosenblat, JD; Shekotikhina, M; Subramaniapillai, M; Suppes, T	1
Chen, J; Qu, Y; Ren, Y; Tang, X; Zhang, C; Zhang, Y; Zou, S	1
De Sousa, RT; Fernandes, F; Leite, CC; Machado-Vieira, R; Otaduy, MC; Scotti-Muzzi, E; Soeiro-de-Souza, MG	1
Bond, DJ; Honer, WG; Lam, RW; Lang, DJ; MacMillan, EL; Silveira, LE; Su, W; Torres, IJ; Yatham, LN	1
Clark, E; Huber, RS; Kondo, DG; Prescot, AP; Renshaw, PF; Shi, XF; Yurgelun-Todd, DA	1
Huang, J; Jia, Y; Lai, S; Liao, X; Sun, Y; Wang, Y; Zhang, S; Zhao, H; Zhong, S	1
Galińska-Skok, B; Gierus, J; Marcinowicz, P; Mosiolek, A; Szulc, A; Waszkiewicz, N; Wiedlocha, M	1
Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E	1
Lafer, B; Leite, C; Machado-Vieira, R; Moreno, RA; Nery, FG; Otaduy, MCG; Soeiro-de-Souza, MG	1
Chen, G; Jia, Y; Lai, S; Liao, X; Liu, T; Wang, Y; Zhong, S	1
Bustillo, JR; Chavez, L; Gasparovic, C; Jones, T; Lenroot, RK; Lin, D; Qualls, C	1
Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M	1
Adler, CM; Blom, TJ; Borgelt, L; Chu, WJ; DelBello, MP; Eliassen, JC; Komoroski, RA; Lee, JH; Rummelhoff, E; Strakowski, SM; Tallman, M; Weber, W; Welge, JA	1
Chen, X; Du, F; Fan, X; Huynh, P; Lewandowski, KE; Öngür, D	1
Adler, CM; Chu, WJ; DelBello, MP; Jarvis, KB; Kim, MJ; Lee, JH; Rummelhoff, E; Strakowski, SM; Weber, WA; Welge, J	1
Adler, CM; Chu, WJ; Delbello, MP; Jarvis, KB; Kim, MJ; Lee, JH; Norris, MM; Strakowski, SM; Weber, W	1
Anand, A; Dydak, U; Dzemidzic, M; Gunn, AD; Harezlak, J; Karne, HS; Nixon, J; Xu, J	1
Cowen, PJ; Godlewska, BR; Goodwin, GM; Near, J; Yip, SW	1
Gigante, AD; Lafer, B; Yatham, LN	1
Adleman, NE; Bararpour, L; Chang, KD; Howe, M; Jo, B; Kelley, RG; Singh, MK; Spielman, D	1
Alda, M; Blagdon, R; Calkin, C; Hajek, T; Slaney, C	1
Adler, CM; Bitter, SM; Chu, WJ; DelBello, MP; Eliassen, JC; Strakowski, SM; Weber, WA	1
Huang, L; Jia, Y; Ling, X; Liu, S; Wang, Y; Xiang, Q; Zhao, G; Zhong, S	1
Cohen, BM; Du, F; Goldbach, JR; Lewandowski, KE; Ongür, D; Sehovic, S; Sperry, SH	1
Algın, O; Atagün, MI; Can, SS; Çayköylü, A; Karakaş-Uğurlu, G; Moore, CM; Öngür, D; Phillips, ML; Şıkoğlu, EM; Ulusoy-Kaymak, S	1
Abulseoud, OA; Baruth, JM; Choi, DS; Croarkin, PE; Frye, MA; Port, JD; Thomas, MA	1
Ehrlich, A; Gallinat, J; Pehrs, C; Schubert, F	1
Bond, DJ; Bücker, J; Kapczinski, F; Kozicky, JM; MacMillan, EL; Muralidharan, K; Rosa, AR; Silveira, LE; Yatham, LN	1
Aydin, B; Gökmen, N; Olson, D; Renshaw, P; Yildiz, A; Yurt, A	1
Ghanizadeh, A; Lotfi, M; Razeghian, L; Shafiee, S; Sigaroudi, MO	1
Guan, JT; Guo, XB; Li, H; Liu, CF; Ou, SM; Shen, ZW; Tan, HZ; Wang, XQ; Wen, CH; Wu, RH; Xu, CT; Zhang, J; Zhang, YN	1
Chen, K; Guan, J; Li, H; Liang, C; Shen, Z; Wu, R; Xiao, B; Xu, C; Xu, H; Zhang, J; Zhang, Y	1
Jia, Y; Lai, S; Liao, X; Liu, T; Wang, B; Wang, Y; Zhong, S	1
Cohen, BM; Jensen, JE; Lundy, M; Öngür, D; Prescot, AP; Renshaw, PF; Stork, C	1
Backens, M; Bondy, B; Falkai, P; Gruber, O; Möller, HJ; Reith, W; Scherk, H; Schneider-Axmann, T; Usher, J; Wobrock, T; Zill, P	1
Berlow, YA; Finn, CT; Forester, BP; Moore, CM; Renshaw, PF; Wardrop, M	1
Adler, CM; Cecil, KM; DelBello, MP; Patel, NC; Strakowski, SM	1
Brotman, MA; Dickstein, DP; Knopf, L; Leibenluft, E; Onelio, L; Pine, DS; Rich, BA; Towbin, KE; Van Der Veen, JW	1
Erfurth, A; Michael, N; Pfleiderer, B	1
Renshaw, PF	1
Hall, GB; MacQueen, GM; Milne, AM; Senaratne, R	1
Chen, HH; Hatch, JP; Lafer, B; Monkul, ES; Nery, FG; Nicoletti, MA; Soares, JC; Stanley, JA	1
Deckersbach, T; Iosifescu, DV; Moore, CM; Nierenberg, AA; Ostacher, MJ; Sachs, GS; Tilley, CA	1
Cohen, BM; Jensen, JE; Olson, DP; Ongür, D; Prescot, AP; Renshaw, PF; Rouse, ED	1
Backens, M; Falkai, P; Gruber, O; Kemmer, C; Reith, W; Scherk, H; Schneider-Axmann, T; Usher, J	2
Adleman, N; Alegria, D; Chang, K; Howe, M; Reiss, A; Singh, M; Spielman, D	1
Reynolds, GP; Reynolds, LM	1
Halasz, S; Kliment, E; Sumegi, A	1
Caetano, SC; Chen, HH; Fonseca, M; Hatch, JP; Hunter, K; Lafer, B; Nicoletti, M; Olvera, RL; Pliszka, SR; Sanches, M; Soares, JC; Stanley, JA	1
Acquaye, T; Adams, E; Chang, KD; Howe, M; Kelley, R; Libby, A; Reiss, A; Singh, MK; Spielman, D	1
Backens, M; Ekawardhani, S; Falkai, P; Gruber, O; Hasan, A; Meyer, J; Reith, W; Scherk, H; Schmitt, A; Schneider-Axmann, T; Wobrock, T	1
Adler, C; Chu, WJ; Delbello, M; Fleck, D; Jarvis, K; Shahana, N; Strakowski, S; Welge, J	1
Alda, M; Bauer, M; Bohner, G; Cullis, J; Hajek, T; Klingebiel, R; Macqueen, GM; O'Donovan, C; Pfennig, A; Ploch, J; Young, LT	1
Adler, C; Bryan, H; Chang, K; Chu, WJ; Delbello, M; Eliassen, J; Garrett, A; Howe, M; Kelley, R; Mills, N; Spielman, D; Strakowski, SM	1
Duffy, S; Hermens, DF; Hickie, IB; Lagopoulos, J; Naismith, SL; Scott, E; Tobias-Webb, J; White, D	1
Cecil, KM; DelBello, MP; Morey, R; Strakowski, SM	1
Asghar, SJ; Hanstock, CC; O'Donnell, T; Silverstone, PH; Ulrich, M; Wu, RH	1
Arolt, V; Erfurth, A; Gössling, M; Heindel, W; Michael, N; Ohrmann, P; Pfleiderer, B	1
Anzalone, S; Deicken, RF; Feiwell, R; Pegues, MP; Soher, B	1
Bertolino, A; Callicott, JH; Frye, M; Mattay, VS; Post, R; Rakow, R; Shelton-Repella, J; Weinberger, DR	1
Adleman, N; Barnea-Goraly, N; Chang, K; Dienes, K; Ketter, T; Reiss, A	1
Nudmamud, S; Reynolds, GP; Reynolds, LM	1
Barnett, S; Belin, T; Davanzo, P; McCracken, J; Mintz, J; Santoro, E; Thomas, MA; Venkatraman, TN; Yue, K	1
Cecil, KM; DelBello, MP; Sellars, MC; Strakowski, SM	1
Berger, G; Desmond, P; McGorry, PD; Pantelis, C; Phillips, LJ; Velakoulis, D; Wood, SJ; Yung, AR	1
Altamura, M; Antonucci, N; Bertolino, A; Blasi, G; Brudaglio, F; Nardini, M; Scarabino, T; Sciota, D; Weinberger, DR	1
Folgierini, M; Frey, BN; Kapczinski, F; Machado-Vieira, R; Nicoletti, M; Soares, JC; Stanley, JA	1
Brambilla, P; Frank, E; Keshavan, MS; Kupfer, D; Mallinger, AG; Nicoletti, MA; Sassi, RB; Soares, JC; Stanley, JA	1
Axelson, D; Birmaher, B; Brambilla, P; Keshavan, MS; Nicoletti, MA; Ramos, RT; Ryan, N; Sassi, RB; Soares, JC; Stanley, JA	1
Adler, CM; Cecil, KM; Daniels, JP; DelBello, MP; Strakowski, SM	1
Chang, KD; Gallelli, KA; Howe, M; Karchemskiy, A; Reiss, A; Spielman, D; Wagner, CM	1
Ankerst, DP; Yildiz-Yesiloglu, A	1
Atmaca, M; Ogur, E; Ozdemir, H; Poyraz, AK; Tezcan, E; Yildirim, H	1
Coyle, JT; Frye, MA; Huggins, T; Post, RM; Tsai, GE	1
Amaral, JA; Caetano, SC; Cerri, GG; de Castro, CC; Issler, CK; Lafer, B; Tamada, RS	1
Frangou, S; Lewis, M; Simmons, A; Wollard, J	1
Adler, CM; Bryan, HS; Cecil, KM; DelBello, MP; Patel, NC; Stanford, KE; Strakowski, SM	1
Ashworth, F; Bhagwagar, Z; Cowen, PJ; Evans, J; Jezzard, P; Matthews, PM; Sule, A; Wylezinska, M	1
Kim, YK; Leonard, BE; Myint, AM; Park, SH; Scharpé, S; Steinbusch, HW; Verkerk, R	1
Binesh, N; Curran, JG; Davanzo, P; Frye, MA; Guze, B; Mintz, J; O'Neill, J; Thomas, MA; Ventura, J; Yue, K	1
Caetano, SC; Chen, HH; Frey, BN; Hatch, JP; Kapczinski, F; Monkul, ES; Nery, FG; Nicoletti, MA; Ortiz, O; Soares, JC; Stanley, JA	1
Ivanovski, B; Lagopoulos, J; Malhi, GS; Moss, K; Sachdev, P; Wen, W	1
Caetano, SC; Chen, HH; Fonseca, M; Hatch, JP; Hunter, K; Nicoletti, M; Olvera, RL; Pliszka, SR; Soares, JC; Stanley, JA	1
Bowden, CL; Escamilla, MA; Frey, BN; Hatch, JP; Matsuo, K; Nery, FG; Nicoletti, MA; Soares, JC; Stanley, JA; Walss-Bass, C	1
Benito, C; Desco, M; Leal, I; Molina, V; Palomo, T; Rebolledo, R; Reig, S; Sánchez, J; Sanz, J; Sarramea, F	1
Backens, M; Falkai, P; Gruber, O; Kemmer, C; Kraft, S; Meyer, J; Reith, W; Scherk, H; Schneider-Axmann, T; Usher, J	1
Marcus, SM; Mrazek, DA; Port, JD; Unal, SS	1
Bahn, S; Griffin, JL; Holmes, E; Huang, JT; Lan, MJ; Manji, H; McLoughlin, GA; Tsang, TM; Yuan, P	1
Bajbouj, M; Bubner, M; Colla, M; Heidenreich, JO; Heuser, I; Kronenberg, G; Luborzewski, A; Schubert, F; Seifert, F	1
Dickstein, DP; Knopf, L; Leibenluft, E; Pine, DS; Towbin, KE; van der Veen, JW	1
Albert, C; Cabaleiro, F; de Luxan, A; Galán, R; Leal, I; Luque, R; Molina, V; Osuna, MI; Prieto, D; Ruiz, M; Sarramea Crespo, F; Sau, P	1
Adler, CM; Cecil, KM; DelBello, MP; Patel, NC; Stanford, KE; Strakowski, SM	1
Kloos, A; Weller, EB; Weller, RA	1
Daunderer, M	1
Hamakawa, H; Kato, N; Kato, T; Murashita, J	1
Igarashi, Y; Isoda, H; Ochiai, M; Ohara, K; Suzuki, Y; Takeda, H; Takehara, Y	1
Adalsteinsson, E; Ketter, TA; Sachs, N; Spielman, D; Tate, DL; Winsberg, ME	1
Castillo, M; Courvoisie, H; Hooper, SR; Kwock, L	1
Bebchuk, JM; Chen, G; Faulk, MW; Glitz, DA; Hasanat, K; Jolkovsky, L; Koch, S; Manji, HK; Moore, GJ; Seraji-Bozorgzad, N; Wilds, IB	1
Bebchuk, JM; Chen, G; Manji, HK; Menji, HK; Moore, GJ; Wilds, IB	1
Belin, T; Davanzo, P; McCracken, J; Oshiro, T; Strober, M; Thomas, MA; Yue, K	1
Deicken, RF; Eliaz, Y; Feiwell, R; Schuff, N	1
Bárány, M; Davis, JM; Sharma, R; Venkatasubramanian, PN	1
Cohen, BM; Gonzalez, RG; Guimaraes, AR; Lafer, B; Miller, C; Renshaw, PF; Sachs, GS; Stoll, AL	1
Imiela, M; Müller-Oerlinghausen, B	1
Allsopp, MN; Hullin, RP; Rees, JR	1
Consbruch, U; Degkwitz, R; Orth, M	1
Jenner, FA	1

Reviews

6 review(s) available for aspartic acid and Affective Psychosis, Bipolar

Article	Year
Glutamatergic and N-Acetylaspartate Metabolites in Bipolar Disorder: A Systematic Review and Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies. International journal of molecular sciences, 2022, Aug-11, Volume: 23, Issue:16 Topics: Aspartic Acid; Bipolar Disorder; Depressive Disorder, Major; Glutamic Acid; Glutamine; Humans; Proton Magnetic Resonance Spectroscopy	2022
Proton magnetic resonance spectroscopy changes after lithium treatment. Systematic review. Psychiatry research. Neuroimaging, 2018, 03-30, Volume: 273 Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Choline; Cross-Sectional Studies; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Lithium Compounds; Proton Magnetic Resonance Spectroscopy; Treatment Outcome	2018
Metabolomics in patients with psychosis: A systematic review. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2018, Volume: 177, Issue:6 Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan	2018
Applications for magnetic resonance imaging in bipolar disorder. CNS spectrums, 2007, Volume: 12, Issue:6 Suppl 8 Topics: Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy	2007
Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: a systematic review of the in vivo proton magnetic resonance spectroscopy findings. Progress in neuro-psychopharmacology & biological psychiatry, 2006, Aug-30, Volume: 30, Issue:6 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy	2006
Biologic basis of bipolar disorder in children and adolescents. Current psychiatry reports, 2008, Volume: 10, Issue:2 Topics: Adolescent; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Child; Energy Metabolism; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Humans; Lithium Compounds; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuropsychological Tests	2008

Trials

16 trial(s) available for aspartic acid and Affective Psychosis, Bipolar

Article	Year
Effects of infliximab on brain neurochemistry of adults with bipolar depression. Journal of affective disorders, 2021, 02-15, Volume: 281 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Glutamic Acid; Humans; Infliximab; Neurochemistry; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy	2021
A Magnetic Resonance Spectroscopy Study of Lovastatin for Treating Bipolar Mood Disorder: A 4-Week Randomized Double-Blind, Placebo- Controlled Clinical Trial. Recent patents on inflammation & allergy drug discovery, 2017, Volume: 10, Issue:2 Topics: Adolescent; Adult; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iran; Lovastatin; Magnetic Resonance Spectroscopy; Male; Middle Aged; Patents as Topic; Time Factors; Young Adult	2017
Brain lithium, N-acetyl aspartate and myo-inositol levels in older adults with bipolar disorder treated with lithium: a lithium-7 and proton magnetic resonance spectroscopy study. Bipolar disorders, 2008, Volume: 10, Issue:6 Topics: Aged; Aged, 80 and over; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Cross-Sectional Studies; Female; Humans; Inositol; Linear Models; Lithium Carbonate; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons	2008
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation. Journal of child and adolescent psychopharmacology, 2009, Volume: 19, Issue:1 Topics: Adolescent; Antimanic Agents; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Child; Creatine; Diagnosis, Differential; Double-Blind Method; Female; Glutamine; Humans; Inositol; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Mood Disorders; Single-Blind Method	2009
Galantamine-ER for cognitive dysfunction in bipolar disorder and correlation with hippocampal neuronal viability: a proof-of-concept study. CNS neuroscience & therapeutics, 2009,Winter, Volume: 15, Issue:4 Topics: Adolescent; Adult; Aged; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Cholinesterase Inhibitors; Cognition Disorders; Female; Galantamine; Humans; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Protons; Young Adult	2009
Neurometabolite effects of response to quetiapine and placebo in adolescents with bipolar depression. Journal of child and adolescent psychopharmacology, 2012, Volume: 22, Issue:4 Topics: Adolescent; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Child; Dibenzothiazepines; Female; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Psychiatric Status Rating Scales; Quetiapine Fumarate; Treatment Outcome	2012
Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients. International clinical psychopharmacology, 2003, Volume: 18, Issue:2 Topics: Adult; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Drug Administration Schedule; Female; Humans; Inositol; Lithium; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Valproic Acid	2003
Decreased N-acetylaspartate in children with familial bipolar disorder. Biological psychiatry, 2003, Jun-01, Volume: 53, Issue:11 Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Child; Creatine; Family Health; Female; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Reference Values	2003
Proton magnetic resonance spectroscopy of the frontal lobe and cerebellar vermis in children with a mood disorder and a familial risk for bipolar disorders. Journal of child and adolescent psychopharmacology, 2003,Winter, Volume: 13, Issue:4 Topics: Aspartic Acid; Bipolar Disorder; Brain Chemistry; Cerebellum; Child; Family; Female; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mood Disorders; Phosphocreatine; Protons; Psychiatric Status Rating Scales; Risk; Wechsler Scales	2003
Neurochemical effects of olanzapine in first-hospitalization manic adolescents: a proton magnetic resonance spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:6 Topics: Adolescent; Analysis of Variance; Antipsychotic Agents; Aspartic Acid; Benzodiazepines; Bipolar Disorder; Brain Chemistry; Case-Control Studies; Child; Female; Humans; Magnetic Resonance Spectroscopy; Male; Olanzapine; Prefrontal Cortex; Prospective Studies; Protons; Psychiatric Status Rating Scales; Time Factors	2006
Preliminary in vivo evidence of increased N-acetyl-aspartate following eicosapentanoic acid treatment in patients with bipolar disorder. Journal of psychopharmacology (Oxford, England), 2007, Volume: 21, Issue:4 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Double-Blind Method; Eicosapentaenoic Acid; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuroprotective Agents; Organ Specificity	2007
Lithium treatment effects on Myo-inositol in adolescents with bipolar depression. Biological psychiatry, 2006, Nov-01, Volume: 60, Issue:9 Topics: Adolescent; Antidepressive Agents; Aspartic Acid; Bipolar Disorder; Child; Female; Humans; Inositol; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Time Factors	2006
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation. Psychiatry research, 2008, May-30, Volume: 163, Issue:1 Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Brain Mapping; Cerebral Cortex; Chronic Disease; Creatine; Diagnosis, Differential; Dominance, Cerebral; Double-Blind Method; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Irritable Mood; Lithium Compounds; Magnetic Resonance Spectroscopy; Mood Disorders; Phosphocreatine	2008
Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects? Biological psychiatry, 2000, Jul-01, Volume: 48, Issue:1 Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain; Double-Blind Method; Female; Gene Expression Regulation; Genes, bcl-2; Humans; Lithium; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroprotective Agents; Prospective Studies	2000
Lithium-induced increase in human brain grey matter. Lancet (London, England), 2000, Oct-07, Volume: 356, Issue:9237 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain; Female; Humans; Lithium; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents	2000
Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4 Topics: Adolescent; Area Under Curve; Aspartic Acid; Bipolar Disorder; Child; Creatine; Demography; Drug Administration Schedule; Female; Gyrus Cinguli; Humans; Inositol; Lithium; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome	2001

Other Studies

91 other study(ies) available for aspartic acid and Affective Psychosis, Bipolar

Article	Year
Metabolic abnormalities in the basal ganglia and cerebellum in bipolar disorder: A multi-modal MR study. Journal of affective disorders, 2022, 03-15, Volume: 301 Topics: Aspartic Acid; Basal Ganglia; Bipolar Disorder; Cerebellum; Creatine; Cross-Sectional Studies; Humans; Magnetic Resonance Imaging	2022
Elevated choline in dorsolateral prefrontal cortex of lithium responders with bipolar I disorder. Asian journal of psychiatry, 2023, Volume: 79 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dorsolateral Prefrontal Cortex; Humans; Lithium; Magnetic Resonance Spectroscopy; Prefrontal Cortex	2023
Altered biochemical metabolism and its lateralization in the cortico-striato-cerebellar circuit of unmedicated bipolar II depression. Journal of affective disorders, 2019, 12-01, Volume: 259 Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Cerebellum; Choline; Creatine; Cross-Sectional Studies; Female; Functional Laterality; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; White Matter; Young Adult	2019
Neurometabolic alterations in bipolar disorder with anxiety symptoms: A proton magnetic resonance spectroscopy study of the prefrontal whiter matter. Psychiatry research, 2021, Volume: 299 Topics: Anxiety; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Humans; Proton Magnetic Resonance Spectroscopy	2021
Anterior cingulate cortex neuro-metabolic changes underlying lithium-induced euthymia in bipolar depression: A longitudinal European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2021, Volume: 49 Topics: Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Gyrus Cinguli; Humans; Inositol; Lithium; Proton Magnetic Resonance Spectroscopy	2021
Diagnosis and body mass index effects on hippocampal volumes and neurochemistry in bipolar disorder. Translational psychiatry, 2017, 03-28, Volume: 7, Issue:3 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Body Mass Index; Brain; Case-Control Studies; Creatine; Dipeptides; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Obesity; Organ Size; Overweight; Phosphatidylcholines; Phosphocreatine; Young Adult	2017
Relationship of executive functioning deficits to N-acetyl aspartate (NAA) and gamma-aminobutyric acid (GABA) in youth with bipolar disorder. Journal of affective disorders, 2018, 01-01, Volume: 225 Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Brain; Case-Control Studies; Executive Function; Female; gamma-Aminobutyric Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Young Adult	2018
Biochemical abnormalities in basal ganglia and executive dysfunction in acute- and euthymic-episode patients with bipolar disorder: A proton magnetic resonance spectroscopy study. Journal of affective disorders, 2018, 01-01, Volume: 225 Topics: Adult; Aspartic Acid; Basal Ganglia; Biomarkers; Bipolar Disorder; Brain; Brain Chemistry; Case-Control Studies; Choline; Corpus Striatum; Creatine; Cyclothymic Disorder; Executive Function; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy	2018
Lithium-associated anterior cingulate neurometabolic profile in euthymic Bipolar I disorder: A Journal of affective disorders, 2018, 12-01, Volume: 241 Topics: Adult; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Brain; Brain Chemistry; Choline; Cyclothymic Disorder; Female; Gyrus Cinguli; Humans; Inositol; Lithium Compounds; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Treatment Outcome	2018
Associations between executive function impairment and biochemical abnormalities in bipolar disorder with suicidal ideation. Journal of affective disorders, 2018, 12-01, Volume: 241 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Case-Control Studies; Cerebral Cortex; Choline; Corpus Striatum; Creatine; Executive Function; Female; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Suicidal Ideation; Thalamus; Young Adult	2018
Proton magnetic resonance spectroscopic imaging of gray and white matter in bipolar-I and schizophrenia. Journal of affective disorders, 2019, 03-01, Volume: 246 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Female; Glutamine; Gray Matter; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; White Matter; Young Adult	2019
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:8 Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome	2019
Neurophysiological effects of multiple mood episodes in bipolar disorder. Bipolar disorders, 2019, Volume: 21, Issue:6 Topics: Adult; Affect; Amygdala; Aspartic Acid; Attention; Bipolar Disorder; Brain; Brain Mapping; Cerebral Cortex; Corpus Striatum; Emotions; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Prefrontal Cortex; Thalamus	2019
Role of glia in prefrontal white matter abnormalities in first episode psychosis or mania detected by diffusion tensor spectroscopy. Schizophrenia research, 2019, Volume: 209 Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Myelin Sheath; Neuroglia; Neurons; Prefrontal Cortex; Psychotic Disorders; Schizophrenia; White Matter; Young Adult	2019
Neurochemical effects of quetiapine in patients with bipolar mania: a proton magnetic resonance spectroscopy study. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:4 Topics: Adolescent; Adult; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Dibenzothiazepines; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Prospective Studies; Quetiapine Fumarate; Remission Induction; Time Factors; Treatment Outcome; Young Adult	2013
Magnetic resonance spectroscopy imaging of lactate in patients with bipolar disorder. Psychiatry research, 2013, Sep-30, Volume: 213, Issue:3 Topics: Adolescent; Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Young Adult	2013
Neurochemical abnormalities in unmedicated bipolar depression and mania: a 2D 1H MRS investigation. Psychiatry research, 2013, Sep-30, Volume: 213, Issue:3 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Tritium; Young Adult	2013
Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy. Psychopharmacology, 2014, Volume: 231, Issue:2 Topics: Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Female; Functional Neuroimaging; gamma-Aminobutyric Acid; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Pilot Projects; Prefrontal Cortex; Young Adult	2014
(1)H-MRS of hippocampus in patients after first manic episode. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2014, Volume: 15, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Glutamic Acid; Glutamine; Hippocampus; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscopy; Male; Neurons; Prospective Studies; Time Factors; Young Adult	2014
Prospective neurochemical characterization of child offspring of parents with bipolar disorder. Psychiatry research, 2013, Nov-30, Volume: 214, Issue:2 Topics: Adolescent; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Child; Child of Impaired Parents; Creatine; Family Health; Female; Humans; Inositol; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons	2013
Type 2 diabetes mellitus: a potentially modifiable risk factor for neurochemical brain changes in bipolar disorders. Biological psychiatry, 2015, Feb-01, Volume: 77, Issue:3 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Creatine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Risk Factors	2015
N-acetyl aspartate levels in adolescents with bipolar and/or cannabis use disorders. Journal of dual diagnosis, 2014, Volume: 10, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Female; Humans; Male; Marijuana Abuse; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Young Adult	2014
Similarities of biochemical abnormalities between major depressive disorder and bipolar depression: a proton magnetic resonance spectroscopy study. Journal of affective disorders, 2014, Volume: 168 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Young Adult	2014
Myelin vs axon abnormalities in white matter in bipolar disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Mar-13, Volume: 40, Issue:5 Topics: Adult; Aspartic Acid; Axons; Bipolar Disorder; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Psychotic Disorders; White Matter	2015
Investigation of Heschl's gyrus and planum temporale in patients with schizophrenia and bipolar disorder: a proton magnetic resonance spectroscopy study. Schizophrenia research, 2015, Volume: 161, Issue:2-3 Topics: Adult; Analysis of Variance; Aspartic Acid; Auditory Cortex; Bipolar Disorder; Creatine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Schizophrenia; Temporal Lobe; Young Adult	2015
N-acetylaspartate normalization in bipolar depression after lamotrigine treatment. Bipolar disorders, 2015, Volume: 17, Issue:4 Topics: Adult; Aged; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Dipeptides; Female; Gyrus Cinguli; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Triazines	2015
Alterations of cerebral glutamate in the euthymic state of patients with bipolar disorder. Psychiatry research, 2015, Aug-30, Volume: 233, Issue:2 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Female; Glutamic Acid; Gyrus Cinguli; Hippocampus; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy	2015
Hippocampal neurochemical markers in bipolar disorder patients following the first-manic episode: A prospective 12-month proton magnetic resonance spectroscopy study. The Australian and New Zealand journal of psychiatry, 2017, Volume: 51, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Female; Glutamic Acid; Glutamine; Hippocampus; Humans; Male; Prospective Studies; Proton Magnetic Resonance Spectroscopy; Young Adult	2017
Trait-related alterations of N-acetylaspartate in euthymic bipolar patients: A longitudinal proton magnetic resonance spectroscopy study. Journal of affective disorders, 2016, Volume: 206 Topics: Adult; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Cyclothymic Disorder; Female; Frontal Lobe; Gyrus Cinguli; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Phosphocreatine; Prefrontal Cortex	2016
Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders. Scientific reports, 2016, 11-21, Volume: 6 Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Depressive Disorder, Major; Glutamine; Gray Matter; Humans; Inositol; Organ Specificity	2016
Differential neurometabolite alterations in brains of medication-free individuals with bipolar disorder and those with unipolar depression: a two-dimensional proton magnetic resonance spectroscopy study. Bipolar disorders, 2016, Volume: 18, Issue:7 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Female; Gyrus Cinguli; Humans; Inositol; Male; Middle Aged; Parietal Lobe; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Statistics as Topic	2016
A comparison of neurometabolites between remitted bipolar disorder and depressed bipolar disorder: A proton magnetic resonance spectroscopy study. Journal of affective disorders, 2017, Mar-15, Volume: 211 Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Female; Humans; Male; Middle Aged; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; White Matter	2017
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania. Biological psychiatry, 2008, Oct-15, Volume: 64, Issue:8 Topics: Acute Disease; Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Cerebral Cortex; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Neuroglia; Neurons; Neurotransmitter Agents; Occipital Lobe; Parietal Lobe; Pilot Projects; Reference Values; Schizophrenia; Synaptic Transmission; Young Adult	2008
SNAP-25 genotype influences NAA/Cho in left hippocampus. Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:11 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; DNA; Female; Genotype; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Obsessive-Compulsive Disorder; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Schizophrenia; Synaptosomal-Associated Protein 25	2008
Neurochemical alterations in adolescent bipolar depression: a proton magnetic resonance spectroscopy pilot study of the prefrontal cortex. Journal of child and adolescent psychopharmacology, 2008, Volume: 18, Issue:6 Topics: Adolescent; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Pilot Projects; Prefrontal Cortex	2008
Elevated metabolites within dorsolateral prefrontal cortex in rapid cycling bipolar disorder. Psychiatry research, 2009, Apr-30, Volume: 172, Issue:1 Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Functional Laterality; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex	2009
Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study. Psychiatry research, 2009, Jun-30, Volume: 172, Issue:3 Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Female; Frontal Lobe; Functional Laterality; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphorylcholine; Psychiatric Status Rating Scales; Severity of Illness Index	2009
Bipolar disorder comorbid with alcoholism: a 1H magnetic resonance spectroscopy study. Journal of psychiatric research, 2010, Volume: 44, Issue:5 Topics: Adult; Age Factors; Alcoholism; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain; Comorbidity; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Sex Factors	2010
T2 relaxation time abnormalities in bipolar disorder and schizophrenia. Magnetic resonance in medicine, 2010, Volume: 63, Issue:1 Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Schizophrenia; Tissue Distribution	2010
Cortical neurochemistry in euthymic patients with bipolar I disorder. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Topics: Adult; Affect; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Female; Gyrus Cinguli; Humans; Inositol; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Prefrontal Cortex; Reference Values; Sex Factors; Young Adult	2009
Brain glutamatergic characteristics of pediatric offspring of parents with bipolar disorder. Psychiatry research, 2010, May-30, Volume: 182, Issue:2 Topics: Adolescent; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Child; Child of Impaired Parents; Cohort Studies; Female; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Pediatrics; Protons; Psychiatric Status Rating Scales	2010
Differential regional N-acetylaspartate deficits in postmortem brain in schizophrenia, bipolar disorder and major depressive disorder. Journal of psychiatric research, 2011, Volume: 45, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Depressive Disorder, Major; Dipeptides; Female; Humans; Male; Middle Aged; Schizophrenia	2011
[Application of lamotrigine in bipolar disorder--3T MR spectroscopy follow up (part 1)]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2010, Volume: 12, Issue:3 Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Excitatory Amino Acid Antagonists; Female; Hippocampus; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Treatment Outcome; Triazines; Young Adult	2010
Lower N-acetyl-aspartate levels in prefrontal cortices in pediatric bipolar disorder: a ¹H magnetic resonance spectroscopy study. Journal of the American Academy of Child and Adolescent Psychiatry, 2011, Volume: 50, Issue:1 Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Diagnostic and Statistical Manual of Mental Disorders; Female; Glycerylphosphorylcholine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorylcholine; Prefrontal Cortex; Protons	2011
Neurochemical deficits in the cerebellar vermis in child offspring of parents with bipolar disorder. Bipolar disorders, 2011, Volume: 13, Issue:2 Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Cerebellum; Child; Choline; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Protons; Psychiatric Status Rating Scales	2011
Association of the brain-derived neurotrophic factor val66met polymorphism with magnetic resonance spectroscopic markers in the human hippocampus: in vivo evidence for effects on the glutamate system. European archives of psychiatry and clinical neuroscience, 2012, Volume: 262, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Creatine; Female; Genetic Association Studies; Genotype; Glutamic Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Memory; Methionine; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Protons; Schizophrenia; Valine; Verbal Learning	2012
Neurochemical alteration in the caudate: implications for the pathophysiology of bipolar disorder. Psychiatry research, 2011, Aug-30, Volume: 193, Issue:2 Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Bipolar Disorder; Brain Mapping; Caudate Nucleus; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Young Adult	2011
Large positive effect of lithium on prefrontal cortex N-acetylaspartate in patients with bipolar disorder: 2-centre study. Journal of psychiatry & neuroscience : JPN, 2012, Volume: 37, Issue:3 Topics: Adult; Aspartic Acid; Bipolar Disorder; Cost of Illness; Female; Humans; Image Processing, Computer-Assisted; Lithium Compounds; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents; Prefrontal Cortex; Psychiatric Status Rating Scales	2012
In vivo glutathione levels in young persons with bipolar disorder: a magnetic resonance spectroscopy study. Journal of psychiatric research, 2013, Volume: 47, Issue:3 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Female; Glutathione; Humans; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Young Adult	2013
Frontal lobe differences in bipolar disorder as determined by proton MR spectroscopy. Bipolar disorders, 2002, Volume: 4, Issue:6 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Choline; Female; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Multivariate Analysis; Protons	2002
Acute mania is accompanied by elevated glutamate/glutamine levels within the left dorsolateral prefrontal cortex. Psychopharmacology, 2003, Volume: 168, Issue:3 Topics: Acute Disease; Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Receptors, Glutamate	2003
Lower concentration of hippocampal N-acetylaspartate in familial bipolar I disorder. The American journal of psychiatry, 2003, Volume: 160, Issue:5 Topics: Adult; Ambulatory Care; Aspartic Acid; Axons; Bipolar Disorder; Choline; Creatine; Family; Functional Laterality; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons	2003
Neuronal pathology in the hippocampal area of patients with bipolar disorder: a study with proton magnetic resonance spectroscopic imaging. Biological psychiatry, 2003, May-15, Volume: 53, Issue:10 Topics: Adult; Aspartic Acid; Bipolar Disorder; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Prefrontal Cortex; Protons	2003
N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: a postmortem study. Biological psychiatry, 2003, Jun-15, Volume: 53, Issue:12 Topics: Aspartic Acid; Autopsy; Biomarkers; Bipolar Disorder; Case-Control Studies; Chromatography, High Pressure Liquid; Depressive Disorder; Dipeptides; Frontal Lobe; Humans; Schizophrenia; Temporal Lobe	2003
Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents. The American journal of psychiatry, 2003, Volume: 160, Issue:8 Topics: Adolescent; Age Factors; Aspartic Acid; Bipolar Disorder; Child; Choline; Creatine; Diagnosis, Differential; Disruptive, Impulse Control, and Conduct Disorders; Female; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Phosphocreatine	2003
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals. Schizophrenia bulletin, 2003, Volume: 29, Issue:4 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Metabolism; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Net; Prefrontal Cortex; Psychotic Disorders; Reference Values; Risk; Schizophrenia; Schizotypal Personality Disorder; Temporal Lobe	2003
Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study. Psychiatry research, 2004, Jul-30, Volume: 131, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Female; Gyrus Cinguli; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Phosphocreatine; Psychiatric Status Rating Scales; Putamen; Reference Values; Thalamus	2004
A proton magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in acute mania. Human psychopharmacology, 2005, Volume: 20, Issue:2 Topics: Acute Disease; Adult; Antimanic Agents; Antipsychotic Agents; Aspartic Acid; Bipolar Disorder; Choline; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Inositol; Magnetic Resonance Imaging; Male; Middle Aged; Patient Selection; Phosphocreatine; Prefrontal Cortex	2005
1H magnetic resonance spectroscopy investigation of the dorsolateral prefrontal cortex in bipolar disorder patients. Journal of affective disorders, 2005, Volume: 86, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Prefrontal Cortex; Radiography	2005
Reduced NAA levels in the dorsolateral prefrontal cortex of young bipolar patients. The American journal of psychiatry, 2005, Volume: 162, Issue:11 Topics: Adolescent; Adult; Age Factors; Aspartic Acid; Bipolar Disorder; Child; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Phosphocreatine; Prefrontal Cortex; Recurrence	2005
N-acetylaspartate levels in bipolar offspring with and at high-risk for bipolar disorder. Bipolar disorders, 2005, Volume: 7, Issue:6 Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Child; Cohort Studies; Creatine; Demography; Family Health; Female; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Protons; Risk Factors	2005
Hippocampal 1H MRS in first-episode bipolar I patients. Progress in neuro-psychopharmacology & biological psychiatry, 2006, Sep-30, Volume: 30, Issue:7 Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Statistics as Topic	2006
Low cerebrospinal fluid glutamate and glycine in refractory affective disorder. Biological psychiatry, 2007, Jan-15, Volume: 61, Issue:2 Topics: Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Drug Resistance; Electroconvulsive Therapy; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; N-Methylaspartate; Statistics as Topic	2007
A 1HMRS study of the anterior cingulate gyrus in euthymic bipolar patients. Human psychopharmacology, 2006, Volume: 21, Issue:4 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Female; Gyrus Cinguli; Humans; Lithium; Magnetic Resonance Spectroscopy; Male; Middle Aged	2006
Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects. Biological psychiatry, 2007, Mar-15, Volume: 61, Issue:6 Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Brain Mapping; Depressive Disorder; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Middle Aged; Occipital Lobe; Reference Values	2007
Tryptophan breakdown pathway in bipolar mania. Journal of affective disorders, 2007, Volume: 102, Issue:1-3 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brief Psychiatric Rating Scale; Female; Gyrus Cinguli; Humans; Kynurenic Acid; Kynurenine; Male; Schizophrenia; Severity of Illness Index; Tryptophan	2007
Reduced concentrations of N-acetylaspartate (NAA) and the NAA-creatine ratio in the basal ganglia in bipolar disorder: a study using 3-Tesla proton magnetic resonance spectroscopy. Psychiatry research, 2007, Apr-15, Volume: 154, Issue:3 Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Creatine; Female; Hospitalization; Humans; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Parietal Lobe; Protons	2007
Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: an in vivo 1H MRS study. Bipolar disorders, 2007, Volume: 9 Suppl 1 Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Energy Metabolism; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Middle Aged; Phosphocreatine; Phospholipids; Prefrontal Cortex; Protons; Severity of Illness Index	2007
Measuring mania metabolites: a longitudinal proton spectroscopy study of hypomania. Acta psychiatrica Scandinavica. Supplementum, 2007, Issue:434 Topics: Adult; Affect; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Brain Mapping; Choline; Energy Metabolism; Female; Frontal Lobe; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Inositol; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Reference Values	2007
Low levels of N-acetyl aspartate in the left dorsolateral prefrontal cortex of pediatric bipolar patients. Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:4 Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Child; Creatine; Female; Glycerylphosphorylcholine; Humans; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorylcholine; Prefrontal Cortex; Puberty	2007
Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder. Neuroreport, 2007, Oct-08, Volume: 18, Issue:15 Topics: Adult; Amino Acid Substitution; Aspartic Acid; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Creatine; Energy Metabolism; Female; Genotype; Humans; Magnetic Resonance Spectroscopy; Male; Methionine; Phosphocreatine; Polymorphism, Genetic; Prefrontal Cortex; Psychiatric Status Rating Scales; Valine	2007
Dorsolateral prefrontal N-acetyl-aspartate concentration in male patients with chronic schizophrenia and with chronic bipolar disorder. European psychiatry : the journal of the Association of European Psychiatrists, 2007, Volume: 22, Issue:8 Topics: Adult; Aspartic Acid; Bipolar Disorder; Cerebrospinal Fluid; Choline; Chronic Disease; Creatine; Fourier Analysis; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Prefrontal Cortex; Reference Values; Schizophrenia	2007
Dopamine transporter genotype influences N-acetyl-aspartate in the left putamen. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Dopamine Plasma Membrane Transport Proteins; Female; Frontal Lobe; Genotype; Gyrus Cinguli; Homozygote; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Minisatellite Repeats; Neurons; Obsessive-Compulsive Disorder; Prefrontal Cortex; Putamen; Reference Values; Young Adult	2009
Metabolic alterations in medication-free patients with bipolar disorder: a 3T CSF-corrected magnetic resonance spectroscopic imaging study. Psychiatry research, 2008, Feb-28, Volume: 162, Issue:2 Topics: Adolescent; Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Brain; Case-Control Studies; Caudate Nucleus; Corpus Striatum; Creatine; Cross-Sectional Studies; Dominance, Cerebral; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values	2008
Neurochemical pathology in hippocampus in euthymic patients with bipolar I disorder. Acta psychiatrica Scandinavica, 2008, Volume: 117, Issue:4 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dysthymic Disorder; Female; Hippocampus; Humans; Inositol; Male; Putamen; Thalamus	2008
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder. Molecular psychiatry, 2009, Volume: 14, Issue:3 Topics: Adult; Analysis of Variance; Animals; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Creatine; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Matched-Pair Analysis; Metabolomics; Middle Aged; Prefrontal Cortex; Rats; Rats, Inbred WKY; Reference Values	2009
Glutamate as a spectroscopic marker of hippocampal structural plasticity is elevated in long-term euthymic bipolar patients on chronic lithium therapy and correlates inversely with diurnal cortisol. Molecular psychiatry, 2009, Volume: 14, Issue:7 Topics: Adult; Aged; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Circadian Rhythm; Creatine; Female; Glutamic Acid; Hippocampus; Humans; Hydrocortisone; Linear Models; Lithium Chloride; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuronal Plasticity; Saliva	2009
Biochemical changes in the cingulum in patients with schizophrenia and chronic bipolar disorder. European archives of psychiatry and clinical neuroscience, 2008, Volume: 258, Issue:7 Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Choline; Chronic Disease; Creatine; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia, Paranoid	2008
Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium. Journal of child and adolescent psychopharmacology, 2008, Volume: 18, Issue:2 Topics: Adolescent; Affect; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Child; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Lithium Compounds; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Software	2008
[Lithium aspartate in drug dependence]. Fortschritte der Medizin, 1982, Sep-02, Volume: 100, Issue:33 Topics: Adult; Alcoholism; Aspartic Acid; Bipolar Disorder; Female; Humans; Lithium; Male; Middle Aged; Substance-Related Disorders	1982
Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders. European archives of psychiatry and clinical neuroscience, 1998, Volume: 248, Issue:1 Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mood Disorders; Phosphocreatine	1998
Proton magnetic resonance spectroscopy of the lenticular nuclei in bipolar I affective disorder. Psychiatry research, 1998, Dec-14, Volume: 84, Issue:2-3 Topics: Adult; Age Factors; Aspartic Acid; Bipolar Disorder; Brain Mapping; Cell Survival; Choline; Corpus Striatum; Creatine; Dominance, Cerebral; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Reference Values	1998
Decreased dorsolateral prefrontal N-acetyl aspartate in bipolar disorder. Biological psychiatry, 2000, Mar-15, Volume: 47, Issue:6 Topics: Adult; Aspartic Acid; Bipolar Disorder; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex	2000
Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations. AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:5 Topics: Aspartic Acid; Basal Ganglia; Bipolar Disorder; Child; Choline; Creatine; Energy Metabolism; Frontal Lobe; Glutamic Acid; Glutamine; Humans; Lipid Metabolism; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Reference Values; Temporal Lobe	2000
Increased thalamic N-acetylaspartate in male patients with familial bipolar I disorder. Psychiatry research, 2001, Feb-28, Volume: 106, Issue:1 Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Humans; Hypertrophy; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuroglia; Thalamus	2001
Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients. Schizophrenia research, 1992, Volume: 8, Issue:1 Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Phosphates; Phosphocreatine; Protons; Schizophrenia; Schizophrenic Psychology	1992
The human brain resonance of choline-containing compounds is similar in patients receiving lithium treatment and controls: an in vivo proton magnetic resonance spectroscopy study. Biological psychiatry, 1992, Nov-15, Volume: 32, Issue:10 Topics: Adult; Aspartic Acid; Bipolar Disorder; Brain; Choline; Corpus Callosum; Humans; Lithium Carbonate; Magnetic Resonance Spectroscopy; Male; Parietal Lobe; Phosphocreatine	1992
[Is lithium aspartate at low serum levels more effective than the usual lithium salts?]. Der Nervenarzt, 1986, Volume: 57, Issue:6 Topics: Adult; Aspartic Acid; Bipolar Disorder; Dose-Response Relationship, Drug; Erythrocytes; Humans; Kinetics; Lithium; Middle Aged	1986
Plasma concentrations of tryptophan and other amino acids in manic-depressive patients. Psychological medicine, 1974, Volume: 4, Issue:3 Topics: Alanine; Arginine; Aspartic Acid; Bipolar Disorder; Emotions; Glutamates; Glycine; Humans; Isoleucine; Leucine; Methionine; Psychology; Serine; Threonine; Tryptophan; Tyrosine	1974
[Clinical administration of lithiumaspartate]. Arzneimittel-Forschung, 1974, Volume: 24, Issue:8 Topics: Acetates; Administration, Oral; Adolescent; Adult; Aspartic Acid; Biopharmaceutics; Bipolar Disorder; Carbonates; Delayed-Action Preparations; Depression; Humans; Lithium; Sulfates; Time Factors	1974
Medical research council unit for metabolic studies in psychiatry, Sheffield. Psychological medicine, 1973, Volume: 3, Issue:3 Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Bipolar Disorder; Catatonia; Circadian Rhythm; Cysteine; Humans; Intellectual Disability; Lithium; Mass Spectrometry; Mental Disorders; Metabolism, Inborn Errors; Periodicity; Phenylketonurias; Sleep; Vasopressins	1973