aspartic acid has been researched along with Affective Disorders in 10 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naismith, SL | 2 |
| Lagopoulos, J | 2 |
| Hermens, DF | 2 |
| White, D | 2 |
| Duffy, SL | 2 |
| Robillard, R | 1 |
| Scott, EM | 1 |
| Hickie, IB | 2 |
| Chitty, KM | 1 |
| Lee, RS | 1 |
| Tickell, A | 1 |
| Paquola, C | 1 |
| Poletti, S | 1 |
| Locatelli, C | 1 |
| Falini, A | 1 |
| Colombo, C | 1 |
| Benedetti, F | 1 |
| Dickstein, DP | 2 |
| Towbin, KE | 2 |
| Van Der Veen, JW | 2 |
| Rich, BA | 1 |
| Brotman, MA | 1 |
| Knopf, L | 2 |
| Onelio, L | 1 |
| Pine, DS | 2 |
| Leibenluft, E | 2 |
| Cecil, KM | 1 |
| DelBello, MP | 1 |
| Sellars, MC | 1 |
| Strakowski, SM | 1 |
| Capizzano, AA | 1 |
| Jorge, RE | 1 |
| Acion, LC | 1 |
| Robinson, RG | 1 |
| Hamakawa, H | 1 |
| Kato, T | 1 |
| Murashita, J | 1 |
| Kato, N | 1 |
| Rasgon, NL | 1 |
| Thomas, MA | 1 |
| Guze, BH | 1 |
| Fairbanks, LA | 1 |
| Yue, K | 1 |
| Curran, JG | 1 |
| Rapkin, AJ | 1 |
| Chouinard, G | 1 |
| Beauclair, L | 1 |
| Geiser, R | 1 |
| Etienne, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain[NCT01844700] | Phase 4 | 14 participants (Actual) | Interventional | 2013-07-31 | Terminated (stopped due to very slow recruitment, no sufficient results) | ||
| Estrogen Use in Protection From Cognitive Decline[NCT00097058] | 71 participants (Anticipated) | Observational | 2003-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | percentage of weight change (Mean) |
|---|---|
| Ziprasidone | 11.58 |
| Aripiprazole, Quetiapine, Risperidone | 5.66 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI percentile (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | 37.67 | 62.5 |
| Ziprasidone | 32 | 59 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | BMI z-score (Mean) | |
|---|---|---|
| baseline | week 12 (n=1, n=2) | |
| Aripiprazole, Quetiapine, Risperidone | -0.37 | 0.38 |
| Ziprasidone | -0.51 | 0.22 |
(NCT01844700)
Timeframe: baseline to week 12
| Intervention | lbs (Mean) | |
|---|---|---|
| baseline | week 12 (n=1,2) | |
| Aripiprazole, Quetiapine, Risperidone | 118.5 | 141 |
| Ziprasidone | 120.5 | 151 |
1 review available for aspartic acid and Affective Disorders
| Article | Year |
|---|---|
In vivo proton magnetic resonance spectroscopy in patients with mood disorders: a technically oriented review.
Topics: Aspartic Acid; Brain Chemistry; Creatine; Frontal Lobe; Glutamates; Hippocampus; Humans; Image Proce | 2007 |
3 trials available for aspartic acid and Affective Disorders
| Article | Year |
|---|---|
Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.
Topics: Adolescent; Antimanic Agents; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar | 2009 |
Proton magnetic resonance spectroscopy of the frontal lobe and cerebellar vermis in children with a mood disorder and a familial risk for bipolar disorders.
Topics: Aspartic Acid; Bipolar Disorder; Brain Chemistry; Cerebellum; Child; Family; Female; Frontal Lobe; H | 2003 |
Proton magnetic resonance spectroscopy in youth with severe mood dysregulation.
Topics: Antimanic Agents; Arousal; Aspartic Acid; Attention Deficit Disorder with Hyperactivity; Bipolar Dis | 2008 |
6 other studies available for aspartic acid and Affective Disorders
| Article | Year |
|---|---|
Delayed circadian phase is linked to glutamatergic functions in young people with affective disorders: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Female; Glutamic Acid; Glutathione; Gyrus Cinguli; Humans; Male; M | 2014 |
Cluster analysis reveals abnormal hippocampal neurometabolic profiles in young people with mood disorders.
Topics: Adolescent; Adult; Aspartic Acid; Cluster Analysis; Creatine; Female; Glutamic Acid; Hippocampus; Hu | 2015 |
Adverse childhood experiences associate to reduced glutamate levels in the hippocampus of patients affected by mood disorders.
Topics: Adolescent; Adult; Adult Survivors of Child Abuse; Aspartic Acid; Creatine; Female; Glutamic Acid; G | 2016 |
Quantitative proton magnetic resonance spectroscopy of the basal ganglia in patients with affective disorders.
Topics: Adult; Aspartic Acid; Basal Ganglia; Bipolar Disorder; Choline; Creatine; Depressive Disorder; Femal | 1998 |
Menstrual cycle-related brain metabolite changes using 1H magnetic resonance spectroscopy in premenopausal women: a pilot study.
Topics: Adolescent; Aspartic Acid; Brain; Creatine; Female; Frontal Lobe; Humans; Magnetic Resonance Spectro | 2001 |
A pilot study of magnesium aspartate hydrochloride (Magnesiocard) as a mood stabilizer for rapid cycling bipolar affective disorder patients.
Topics: Aspartic Acid; Calcium; Humans; Magnesium; Mood Disorders; Potassium; Research Design; Sodium | 1990 |