Page last updated: 2024-08-17

aspartic acid and Acute Relapsing Multiple Sclerosis

aspartic acid has been researched along with Acute Relapsing Multiple Sclerosis in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	32 (62.75)	29.6817
2010's	16 (31.37)	24.3611
2020's	3 (5.88)	2.80

Authors

Authors	Studies
Al-Iedani, O; Arm, J; Lea, R; Lechner-Scott, J; Ramadan, S; Ribbons, K	1
Cavey, A; Craner, M; DeLuca, GC; Emir, U; Everett, R; Kong, Y; Messina, S; Minne, R; Palace, J; Stagg, CJ; Tackley, G; Tracey, I; Weir, A; Winkler, A	1
Bailey, M; DeStefano, K; Fulbright, RK; Juchem, C; Kurada, AV; Pitt, D; Prinsen, H; Swanberg, KM	1
Gao, X; Li, X; Lin, P; Ni, L; Niu, C; Song, H; Sun, J; Yang, Y; Zhang, K	1
Bellenberg, B; Ellrichmann, G; Gold, R; Haghikia, A; Hoepner, R; Kolb, EM; Lukas, C; Schneider, R	1
Babb, JS; Davitz, MS; Gonen, O; Herbert, J; Kirov, II; Liu, S; Rusinek, H; Tal, A; Wu, WE	1
Fan, Y; Zhou, L	1
Friedrich, MG; Hancock, SE; Raftery, MJ; Truscott, RJ	1
Dönmez, H; Mirza, M; Yetkin, MF	1
Baranovičová, E; Bittšanský, M; Čierny, D; Hnilicová, P; Kantorová, E; Kurča, E; Nosáľ, V; Poláček, H; Sivák, Š; Zeleňák, K	1
Aksu, AO; Anlar, B; Haspolat, S; Karabulut, E; Kurne, A; Kurul, S; Oguz, KK; Senbil, N; Serdaroglu, A; Teber, S	1
Blom, HJ; Bouwman, F; Brundin, L; Dijkstra, CD; Iacobaeus, E; Jakobs, C; Khademi, M; Koel-Simmelink, MJ; Norgren, N; Schepens, M; Teunissen, CE; Twaalfhoven, HA	1
Benedetti, B; Bertolotto, A; Capra, R; Caputo, D; Comi, G; Filippi, M; Martinelli, V; Rocca, MA; Rovaris, M; Zaffaroni, M	1
Altmann, DR; Ciccarelli, O; McLean, MA; Miller, DH; Thompson, AJ; Wheeler-Kingshott, CA; Wimpey, K	1
Babb, JS; Fleysher, L; Fleysher, R; Gonen, O; Herbert, J; Kirov, II; Liu, S	1
aufm Kampe, K; Bartsch, A; Bendszus, M; Biller, A; Classen, J; Gentner, R; Rieckmann, P; Schütz, A; Stefan, K; Toyka, KV; Zeller, D	1
Amato, MP; Ceci, E; D'Amico, E; De Luca, G; Di Monte, E; Direnzo, V; Frigeri, A; Ghezzi, A; Hakiki, B; Iaffaldano, P; Livrea, P; Lugaresi, A; Mastrapasqua, M; Patti, F; Ruggieri, M; Simone, AM; Sola, P; Svelto, M; Tortorella, C; Trojano, M	1
Fekih-Mrissa, N; Gritli, N; Layouni, S; Messadi, A; Mrissa, R; Nsiri, B; Raies, A; Yedeas, M; Zaouali, J	1
Blinkenberg, M; Hanson, LG; Holm, S; Jønsson, A; Mathiesen, HK; Paulson, OB; Sellebjerg, F; Sorensen, PS; Svarer, C; Tscherning, T	1
Bagory, M; Comte, JC; Confavreux, C; Cotton, F; Durand-Dubief, F; Hannoun, S; Ibarrola, D; Sappey-Marinier, D	1
Babb, JS; Gonen, O; Gorynski, E; Grossman, RI; Herbert, J; Inglese, M; Kirov, II; Perry, NN; Rigotti, DJ	1
Babb, JS; Gonen, O; Herbert, J; Kirov, II; Tal, A	1
Bashir, K; Coyle, PK; Hetherington, HP; Krupp, LB; Pan, JW; Whitaker, JN	1
Babb, JS; Gonen, O; Grossman, RI; He, J; Jacobs, D; Li, BS; Listerud, J; Markowitz, CE; Moriarty, DM	1
Casanova, B; Celda, B; Coret, F; Landente, L; Martí-Bonmatí, L; Martínez-Bisbal, MC; Pascual, A; Valero, C	1
Gonen, O; Grossman, RI; Li, BS; Mannon, LJ; Regal, J; Soher, BJ	1
Alecci, M; Cifelli, A; Jezzard, P; Matthews, PM; Palace, J; Wylezinska, M	1
Casanova, B; Celda, B; Coret, F; Espert, R; Gadea, M; Marti-Bonmatí, L; Martínez-Bisbal, MC	1
Falini, A; Filippi, M; Ge, Y; Gonen, O; Grossman, RI; Inglese, M	1
Argente, J; Casado, A; Foronda, J; Izquierdo, G; Piñero, P; Ruiz-Peña, JL; Sellers, G; Uclés, A	1
Babb, JS; Gonen, O; Grossman, RI; Inglese, M; Liu, S; Mannon, LJ	1
Babb, JS; Gonen, O; Grossman, RI; He, J; Inglese, M; Li, BS	1
Hanson, LG; Larsson, HB; Mathiesen, HK; Paulson, OB; Rostrup, E; Sorensen, PS; Tscherning, T	1
De Keyser, J; Mostert, JP; Oudkerk, M; Sijens, PE	1
Altmann, DR; Chard, DT; Davies, G; Griffin, CM; McLean, MA; Miller, DH; Rashid, W; Sastre-Garriga, J; Thompson, AJ; Tiberio, M	1
Bao, F; Buccheister, A; Caon, C; Ching, W; Hu, J; Khan, O; Latif, Z; Lisak, R; Reznar, M; Shen, Y; Tselis, A	1
Andresen, J; Blinkenberg, M; Hanson, LG; Jonsson, A; Mathiesen, HK; Paulson, OB; Sorensen, PS; Tscherning, T	1
Babb, JS; Gonen, O; Grossman, RI; Herbert, J; Inglese, M; Oberndorfer, TA	1
Behrens, TE; Cader, S; Johansen-Berg, H; Matthews, PM; Palace, J; Smith, S; Wylezinska, M	1
Boscá, I; Casanova, B; Celda, B; Coret, F; Marti-Bonmati, L; Martínez-Bisbal, MC; Martínez-Granados, B; Mir, A; Pascual, AM; Valero, C	1
Comi, G; Filippi, M; Judica, E; Martinelli, V; Pulizzi, A; Rovaris, M; Sormani, MP	1
Alonso, J; Montalban, X; Nos, C; Río, J; Rovira, A; Téllez, N; Tintoré, M	1
Cipolotti, L; Dalton, C; Fernando, K; Miller, DH; Ron, MA; Summers, M; Swanton, J	1
Antel, J; Arnold, DL; Duquette, P; Hoge, RD; Matthews, PM; Narayanan, S; Pike, GB; Reddy, H	1
Andersson, PB; Capizzano, AA; Goodkin, DE; Maudsley, AA; Rooney, WD; Soher, BJ; Suhy, J; Waubant, E; Weiner, MW	1
Hagberg, G; Kappos, L; Mader, I; Radue, EW; Roser, W; Seelig, J; Steinbrich, W	1
Barker, GJ; Chard, D; Griffin, CM; Kapeller, P; McLean, MA; Miller, DH; Parker, GJ; Thompson, AJ	1
Helms, G	1
Bisaga, GN; Odinak, MM; Pozdniakov, AV; Tiutin, LA	1
Babb, JS; Bonneville, F; Gonen, O; Grossman, RI; Li, BS; Moriarty, DM	1
Elster, C; Haas, J; Link, A; Mientus, S; Rinneberg, H; Schubert, F; Seifert, F; Walzel, M	1

Trials

6 trial(s) available for aspartic acid and Acute Relapsing Multiple Sclerosis

Article	Year
Randomized trial of erhuangfang for relapsing multiple sclerosis. Neurological research, 2015, Volume: 37, Issue:7 Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspartic Acid; Brain; Creatine; Disability Evaluation; Disease Progression; Drugs, Chinese Herbal; Female; Humans; Magnetic Resonance Spectroscopy; Male; Medicine, Chinese Traditional; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Prospective Studies; Young Adult	2015
Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis. AJNR. American journal of neuroradiology, 2009, Volume: 30, Issue:4 Topics: Adolescent; Age of Onset; Aspartic Acid; Child; Child, Preschool; Choline; Citrulline; Creatine; Demyelinating Diseases; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Myelin Sheath; Protons; Young Adult	2009
Magnetic resonance spectroscopy of normal appearing white matter in early relapsing-remitting multiple sclerosis: correlations between disability and spectroscopy. BMC neurology, 2004, Jun-10, Volume: 4 Topics: Adolescent; Adult; Aged; Aspartic Acid; Axons; Biomarkers; Brain; Creatine; Cross-Sectional Studies; Disability Evaluation; Female; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Predictive Value of Tests; Prospective Studies; Recurrence; Reference Values; Reproducibility of Results; Severity of Illness Index	2004
Axonal metabolic recovery and potential neuroprotective effect of glatiramer acetate in relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 2005, Volume: 11, Issue:6 Topics: Adult; Aspartic Acid; Axons; Creatine; Female; Glatiramer Acetate; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neuroprotective Agents; Peptides; Pilot Projects; Treatment Outcome	2005
Serial proton MR spectroscopy of contrast-enhancing multiple sclerosis plaques: absolute metabolic values over 2 years during a clinical pharmacological study. AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:7 Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Follow-Up Studies; Guanidines; Humans; Image Enhancement; Immunosuppressive Agents; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting	2000
Serial 1H-MRS in relapsing-remitting multiple sclerosis: effects of interferon-beta therapy on absolute metabolite concentrations. Magma (New York, N.Y.), 2002, Volume: 14, Issue:3 Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Image Enhancement; Interferon-beta; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Phantoms, Imaging; Phosphocreatine; Protons	2002

Other Studies

45 other study(ies) available for aspartic acid and Acute Relapsing Multiple Sclerosis

Article	Year
Biochemical Correlations with Fatigue in Multiple Sclerosis Detected by MR 2D Localized Correlated Spectroscopy. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2021, Volume: 31, Issue:3 Topics: Adult; Aspartic Acid; Carnosine; Choline; Creatine; Fatigue; Female; Glutathione; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Young Adult	2021
An In-vivo 1H-MRS short-echo time technique at 7T: Quantification of metabolites in chronic multiple sclerosis and neuromyelitis optica brain lesions and normal appearing brain tissue. NeuroImage, 2021, Volume: 238 Topics: Adult; Aquaporin 4; Aspartic Acid; Autoantibodies; Autoantigens; Brain Chemistry; Female; Gliosis; Glutamates; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nerve Tissue Proteins; Neuromyelitis Optica; Young Adult	2021
In vivo evidence of differential frontal cortex metabolic abnormalities in progressive and relapsing-remitting multiple sclerosis. NMR in biomedicine, 2021, Volume: 34, Issue:11 Topics: Adult; Aged; Aspartic Acid; Choline; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamine; Glutathione; Gray Matter; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neurotransmitter Agents; Young Adult	2021
Metabolic changes in normal appearing white matter in multiple sclerosis patients using multivoxel magnetic resonance spectroscopy imaging. Medicine, 2017, Volume: 96, Issue:14 Topics: Adult; Aspartic Acid; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Proton Magnetic Resonance Spectroscopy; Quality Improvement	2017
Metabolic profiles by 1H-magnetic resonance spectroscopy in natalizumab-associated post-PML lesions of multiple sclerosis patients who survived progressive multifocal leukoencephalopathy (PML). PloS one, 2017, Volume: 12, Issue:4 Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Immunologic Factors; JC Virus; Leukoencephalopathy, Progressive Multifocal; Lipids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Natalizumab; Viral Load	2017
Proton MR spectroscopy of lesion evolution in multiple sclerosis: Steady-state metabolism and its relationship to conventional imaging. Human brain mapping, 2017, Volume: 38, Issue:8 Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Cross-Sectional Studies; Disease Progression; Female; Follow-Up Studies; Humans; Inositol; Longitudinal Studies; Magnetic Resonance Imaging; Male; Multiple Sclerosis, Relapsing-Remitting; Organ Size; Proton Magnetic Resonance Spectroscopy; White Matter; Young Adult	2017
Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset? Acta neuropathologica communications, 2016, 08-12, Volume: 4, Issue:1 Topics: Adult; Aged; Aging; Arginine; Aspartic Acid; Cerebellum; Glutamine; Humans; Isoaspartic Acid; Mass Spectrometry; Middle Aged; Models, Molecular; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Protein Processing, Post-Translational; Proteolysis	2016
Monitoring interferon β treatment response with magnetic resonance spectroscopy in relapsing remitting multiple sclerosis. Medicine, 2016, Volume: 95, Issue:36 Topics: Adult; Aftercare; Aspartic Acid; Case-Control Studies; Chlorine; Creatine; Disability Evaluation; Female; Humans; Immunologic Factors; Interferon-beta; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Neurons; Treatment Outcome; White Matter; Young Adult	2016
Hypothalamic damage in multiple sclerosis correlates with disease activity, disability, depression, and fatigue. Neurological research, 2017, Volume: 39, Issue:4 Topics: Adult; Aging; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectional Studies; Depression; Disability Evaluation; Fatigue; Female; Glutamic Acid; Humans; Hypothalamus; Inositol; Male; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Proton Magnetic Resonance Spectroscopy; Psychiatric Status Rating Scales; Severity of Illness Index	2017
Combination of CSF N-acetylaspartate and neurofilaments in multiple sclerosis. Neurology, 2009, Apr-14, Volume: 72, Issue:15 Topics: Amino Acids; Aspartic Acid; Axons; Biomarkers; Cohort Studies; Disease Progression; Humans; Magnetic Resonance Imaging; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Nerve Degeneration; Neurofilament Proteins; tau Proteins	2009
In-vivo evidence for stable neuroaxonal damage in the brain of patients with benign multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England), 2009, Volume: 15, Issue:7 Topics: Adult; Aspartic Acid; Axons; Biomarkers; Brain; Brain Chemistry; Cell Survival; Cross-Sectional Studies; Disability Evaluation; Disease Progression; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Severity of Illness Index; Young Adult	2009
Spinal cord repair in MS: does mitochondrial metabolism play a role? Neurology, 2010, Mar-02, Volume: 74, Issue:9 Topics: Adult; Aspartic Acid; Axons; Cervical Vertebrae; Disease Progression; Female; Follow-Up Studies; Humans; Linear Models; Logistic Models; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Mitochondria; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Nerve Degeneration; Organ Size; Reactive Oxygen Species; Spinal Cord; Time Factors	2010
Brain metabolite proton T2 mapping at 3.0 T in relapsing-remitting multiple sclerosis. Radiology, 2010, Volume: 254, Issue:3 Topics: Adult; Aspartic Acid; Brain Mapping; Choline; Creatine; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Prospective Studies; Statistics, Nonparametric	2010
Rapid-onset central motor plasticity in multiple sclerosis. Neurology, 2010, Mar-02, Volume: 74, Issue:9 Topics: Adult; Aspartic Acid; Creatine; Cross-Sectional Studies; Female; Humans; Learning; Male; Middle Aged; Motor Activity; Motor Cortex; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Neuronal Plasticity; Pyramidal Tracts; Time Factors; Young Adult	2010
Serum and CSF N-acetyl aspartate levels differ in multiple sclerosis and neuromyelitis optica. Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:12 Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Case-Control Studies; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neuromyelitis Optica	2011
[Implication of platelet-activating factor receptor A224D mutation in susceptibility to relapsing-remitting multiple sclerosis: A Tunisian population study]. Pathologie-biologie, 2012, Volume: 60, Issue:3 Topics: Adult; Alanine; Amino Acid Substitution; Aspartic Acid; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genetics, Population; Humans; Male; Multiple Sclerosis, Relapsing-Remitting; Mutation, Missense; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Severity of Illness Index; Tunisia; Young Adult	2012
Cerebral metabolism, magnetic resonance spectroscopy and cognitive dysfunction in early multiple sclerosis: an exploratory study. Neurological research, 2012, Volume: 34, Issue:1 Topics: Adult; Aspartic Acid; Brain; Cerebral Cortex; Cognition Disorders; Creatine; Female; Glucose; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Positron-Emission Tomography; Regression Analysis; Young Adult	2012
Correlation of diffusion and metabolic alterations in different clinical forms of multiple sclerosis. PloS one, 2012, Volume: 7, Issue:3 Topics: Adult; Aspartic Acid; Choline; Diffusion; Diffusion Tensor Imaging; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Reproducibility of Results; Sensitivity and Specificity	2012
Two-year serial whole-brain N-acetyl-L-aspartate in patients with relapsing-remitting multiple sclerosis. Neurology, 2012, May-01, Volume: 78, Issue:18 Topics: Adult; Aspartic Acid; Biomarkers; Brain; Cohort Studies; Disability Evaluation; Female; Humans; Least-Squares Analysis; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Neurons; Organ Size; Predictive Value of Tests; Prognosis; Statistics as Topic	2012
Serial proton MR spectroscopy of gray and white matter in relapsing-remitting MS. Neurology, 2013, Jan-01, Volume: 80, Issue:1 Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Disability Evaluation; Female; Follow-Up Studies; Functional Neuroimaging; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Protons	2013
Metabolic differences between multiple sclerosis subtypes measured by quantitative MR spectroscopy. Multiple sclerosis (Houndmills, Basingstoke, England), 2002, Volume: 8, Issue:3 Topics: Aspartic Acid; Brain; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting	2002
Relapsing-remitting multiple sclerosis and whole-brain N-acetylaspartate measurement: evidence for different clinical cohorts initial observations. Radiology, 2002, Volume: 225, Issue:1 Topics: Adult; Aspartic Acid; Brain Chemistry; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Prognosis	2002
Evidence of Wallerian degeneration in normal appearing white matter in the early stages of relapsing-remitting multiple sclerosis: a HMRS study. Journal of neurology, 2003, Volume: 250, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Brain; Creatinine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Radiography; Time Factors; Wallerian Degeneration	2003
Brain metabolite profiles of T1-hypointense lesions in relapsing-remitting multiple sclerosis. AJNR. American journal of neuroradiology, 2003, Volume: 24, Issue:1 Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Statistics as Topic	2003
Thalamic neurodegeneration in relapsing-remitting multiple sclerosis. Neurology, 2003, Jun-24, Volume: 60, Issue:12 Topics: Adult; Aspartic Acid; Atrophy; Biomarkers; Body Water; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nerve Degeneration; Nuclear Magnetic Resonance, Biomolecular; Thalamus	2003
Spectroscopic axonal damage of the right locus coeruleus relates to selective attention impairment in early stage relapsing-remitting multiple sclerosis. Brain : a journal of neurology, 2004, Volume: 127, Issue:Pt 1 Topics: Adult; Analysis of Variance; Aspartic Acid; Attention; Axons; Biomarkers; Cognition Disorders; Dichotic Listening Tests; Disability Evaluation; Female; Humans; Linear Models; Locus Coeruleus; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting	2004
Indirect evidence for early widespread gray matter involvement in relapsing-remitting multiple sclerosis. NeuroImage, 2004, Volume: 21, Issue:4 Topics: Adult; Aspartic Acid; Axons; Brain; Brain Mapping; Dominance, Cerebral; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neurons; Reference Values	2004
Three-dimensional proton spectroscopy of deep gray matter nuclei in relapsing-remitting MS. Neurology, 2004, Jul-13, Volume: 63, Issue:1 Topics: Adult; Aspartic Acid; Basal Ganglia; Choline; Creatine; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nuclear Magnetic Resonance, Biomolecular; Thalamic Nuclei	2004
Relapsing-remitting multiple sclerosis: metabolic abnormality in nonenhancing lesions and normal-appearing white matter at MR imaging: initial experience. Radiology, 2005, Volume: 234, Issue:1 Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting	2005
Multi-slice echo-planar spectroscopic MR imaging provides both global and local metabolite measures in multiple sclerosis. Magnetic resonance in medicine, 2005, Volume: 53, Issue:4 Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Echo-Planar Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting	2005
(1)H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings. European radiology, 2006, Volume: 16, Issue:2 Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mathematical Computing; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Reference Values; Software	2006
Metabolite changes in early relapsing-remitting multiple sclerosis. A two year follow-up study. Journal of neurology, 2006, Volume: 253, Issue:2 Topics: Adult; Aspartic Acid; Choline; Creatine; Dipeptides; Female; Follow-Up Studies; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Statistics, Nonparametric; Time Factors	2006
Correlation of global N-acetyl aspartate with cognitive impairment in multiple sclerosis. Archives of neurology, 2006, Volume: 63, Issue:4 Topics: Adult; Aspartic Acid; Brain; Cognition Disorders; Disability Evaluation; Echo-Planar Imaging; Female; Humans; Magnetic Resonance Imaging; Male; Multiple Sclerosis, Relapsing-Remitting; Neuropsychological Tests; Predictive Value of Tests	2006
Reproducibility of three whole-brain N-acetylaspartate decline cohorts in relapsing-remitting multiple sclerosis. AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:2 Topics: Adult; Aspartic Acid; Atrophy; Brain; Cohort Studies; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Reproducibility of Results	2007
Discordant white matter N-acetylasparate and diffusion MRI measures suggest that chronic metabolic dysfunction contributes to axonal pathology in multiple sclerosis. NeuroImage, 2007, May-15, Volume: 36, Issue:1 Topics: Adult; Aspartic Acid; Axons; Brain; Corpus Callosum; Diffusion Magnetic Resonance Imaging; Dominance, Cerebral; Energy Metabolism; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Nerve Fibers, Myelinated; Reference Values	2007
Axonal loss is progressive and partly dissociated from lesion load in early multiple sclerosis. Neurology, 2007, Jul-03, Volume: 69, Issue:1 Topics: Adult; Aspartic Acid; Axons; Brain; Brain Chemistry; Choline; Creatine; Disease Progression; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Relapsing-Remitting; Prospective Studies; Severity of Illness Index	2007
Determinants of disability in multiple sclerosis at various disease stages: a multiparametric magnetic resonance study. Archives of neurology, 2007, Volume: 64, Issue:8 Topics: Adult; Aged; Anisotropy; Aspartic Acid; Brain; Cohort Studies; Cross-Sectional Studies; Diffusion Magnetic Resonance Imaging; Disability Evaluation; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Nervous System Diseases; Periaqueductal Gray; Syndrome; Time Factors	2007
The basal ganglia: a substrate for fatigue in multiple sclerosis. Neuroradiology, 2008, Volume: 50, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Choline; Corpus Striatum; Creatine; Disability Evaluation; Energy Metabolism; Fatigue; Female; Fourier Analysis; Frontal Lobe; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Reference Values; Risk Factors	2008
Cognitive impairment in multiple sclerosis can be predicted by imaging early in the disease. Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:8 Topics: Adolescent; Adult; Aspartic Acid; Atrophy; Brain; Cerebral Ventricles; Cognition Disorders; Cohort Studies; Dipeptides; Disability Evaluation; Female; Follow-Up Studies; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neurologic Examination; Neuropsychological Tests; Predictive Value of Tests; Prospective Studies	2008
Relating axonal injury to functional recovery in MS. Neurology, 2000, Jan-11, Volume: 54, Issue:1 Topics: Adult; Aspartic Acid; Axons; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Motor Cortex; Multiple Sclerosis, Relapsing-Remitting; Neuronal Plasticity; Recovery of Function; Somatosensory Cortex	2000
1H MRSI comparison of white matter and lesions in primary progressive and relapsing-remitting MS. Multiple sclerosis (Houndmills, Basingstoke, England), 2000, Volume: 6, Issue:3 Topics: Adult; Aspartic Acid; Brain; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Protons; Reference Values	2000
Preliminary evidence for neuronal damage in cortical grey matter and normal appearing white matter in short duration relapsing-remitting multiple sclerosis: a quantitative MR spectroscopic imaging study. Journal of neurology, 2001, Volume: 248, Issue:2 Topics: Adult; Aspartic Acid; Brain; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Nerve Degeneration; Time Factors	2001
Volume correction for edema in single-volume proton MR spectroscopy of contrast-enhancing multiple sclerosis lesions. Magnetic resonance in medicine, 2001, Volume: 46, Issue:2 Topics: Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Contrast Media; Creatine; Edema; Female; Gadolinium DTPA; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Regression Analysis; Signal Processing, Computer-Assisted	2001
[Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:4 Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Demyelinating Diseases; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Phosphocreatine; Severity of Illness Index	2001
Whole-brain N-acetylaspartate concentration: correlation with T2-weighted lesion volume and expanded disability status scale score in cases of relapsing-remitting multiple sclerosis. AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:3 Topics: Adult; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Disability Evaluation; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting	2002