Page last updated: 2024-08-17

aspartic acid and Acute Brain Injuries

aspartic acid has been researched along with Acute Brain Injuries in 117 studies

Research

Studies (117)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (2.56)	18.7374
1990's	17 (14.53)	18.2507
2000's	58 (49.57)	29.6817
2010's	34 (29.06)	24.3611
2020's	5 (4.27)	2.80

Authors

Authors	Studies
Ahn, S; Babb, JS; Bushnik, T; Chen, AM; Dehkharghani, S; Gajdošík, M; Gerhalter, T; Im, BS; Kirov, II; Madelin, G; Peralta, R; Sheriff, S; Silver, JM; Tordjman, M; Wall, SP; Zabludovsky, J; Zarate, A	1
Anazodo, UC; Dacey, M; Gomes, J; McIntyre, CW; Penny, JD; Poirier, SE; Théberge, J; van Ginkel, M; Wong, DY	1
Cao, B; Feng, WS; Hao, FX; Jiao, XM; Liang, XW; Zeng, MN; Zheng, XK	1
Gong, M; He, Z; Ling, X; Wang, W; Xu, M; Yue, Q	1
Gao, J; Han, D; Li, J; Li, Q; Liao, C; Luo, Y; Wang, R; Yang, J	1
Basu, SK; Chang, T; Kapse, K; Limperopoulos, C; McCarter, R; Murnick, J; Pradhan, S	1
Berkefeld, J; Güresir, E; Hattingen, E; Hildebrand, C; Jurcoane, A; Pilatus, U; Vatter, H; Wagner, M; Zanella, FE	1
Chang, C; Chang, L; Denny, K; Ernst, T; Green, D; O'Phelan, K; Park, D; Stenger, A	1
Bandak, F; de Lanerolle, NC; Hamid, H; Hetherington, HP; Kulas, J; Ling, G; Pan, JW	1
Bittšanský, M; Demková, A; Dobrota, D; Grossmann, J; Hnilicová, P; Kantorová, E; Kurča, E; Nosál', V; Sivák, Š; Siváková, J	1
Babb, JS; Gonen, O; Grossman, RI; Haemer, G; Kierans, AS; Kirov, II; Lui, YW; Nisenbaum, E	1
Amorini, AM; Belli, A; Di Pietro, V; Lazzarino, G; Logan, A; Signoretti, S; Tavazzi, B; Vagnozzi, R	1
Chen, WS; Hong, L; Li, CQ; Li, JJ; Wang, F; Xing, ZB; Zhang, JH	1
Fievisohn, EM; Hardy, WN; Sajja, VS; Vandevord, PJ	1
DiNapoli, VA; Gerhardt, GA; Hartings, JA; Hinzman, JM; Mahoney, EJ	1
Davitz, MS; Fieremans, E; Gonen, O; Grossman, EJ; Grossman, RI; Inglese, M; Kirov, II; Lui, YW; Novikov, DS	1
Han, L; Hao, S; Hou, Z; Liu, B; Mao, X; Tao, X; Tian, R; Zhang, Q; Zhu, Z	1
Carvalho, F; Carvalho, RA; Cunha, RA; Fonseca, R; Fontes Ribeiro, CA; Jarak, I; Köfalvi, A; Lemos, C; Pereira, FC; Pita, IR; Prediger, RD; Sequeira, AC; Silva, CD	1
Hoch, SE; Kirov, II; Tal, A	1
Gröhn, H; Gröhn, OH; Immonen, RJ; Kharatishvili, I; Niskanen, JP; Pitkänen, A	1
Campistol, J; Capdevila, A; De La Osa, A; García-Cazorla, A; Leist, A; Navarro-Sastre, A; Pérez-Dueñas, B; Pineda, M; Ribes, A; Serrano, M	1
Aygok, GA; Bullock, RM; Fatouros, P; Kettenmann, B; Marmarou, A	1
Fiskum, G; Hopkins, I; McKenna, M; O'Brien, J; Robertson, C; Scafidi, S	1
Amaro, E; Nucci-da-Silva, MP	1
Bigal, M; Brito, C; Jevoux, C; Moreira, P; Sarmento, E; Souza, J	1
Amorini, AM; Belli, A; D'Urso, S; Di Pietro, V; Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R	1
Chen, XR; Fulla-Oller, L; Gillet, B; Lescot, T; Marchand-Leroux, C; Meric, P; Plotkine, M; Po, C; Puybasset, L	1
Ariyannur, PS; Arun, P; Grunberg, NE; Hamilton, K; Ives, JA; Moffett, JR; Namboodiri, AM; Xing, G	1
Blamek, S; Ficek, K; Miszczyk, L; Sońta-Jakimczyk, D; Syguła, D; Tarnawski, R	1
Alger, JR; Asarnow, RF; Babikian, T; Cazalis, F; Copeland, S; Giza, CC; Hilleary, SM; Kernan, CL; Marion, SD; Mink, R; Newman, N; O'Neill, J; Vu, JA	1
Hasak, MP; Hsu, O; Luong, R; Mayer, D; Orduna, J; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM	1
Aaen, GS; Ashwal, S; Colbert, C; Holshouser, BA; Kido, D; McKenney, M; Sheridan, C	1
Arheart, KL; Falcone, S; Gold, S; Govind, V; Harris, L; Jagid, J; Kaliannan, K; Maudsley, AA; Saigal, G	1
Barker, PB; Bertrand, M; Degoankar, M; Horská, A; Munro, CA; Pham, D; Rao, V; Rosenberg, P; Ward, J; Yousem, DM	1
Capizzano, AA; Jorge, RE; Robinson, RG	1
Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R	1
Atkinson, JH; Clifford, D; Collier, AC; Ellis, RJ; Fennema-Notestine, C; Franklin, D; Gelman, B; Grant, I; Heaton, R; Jernigan, T; Lin, K; Marra, C; McArthur, J; McCutchan, A; Morgello, S; Simpson, D; Taylor, MJ	1
Deng-Bryant, Y; Harris, NG; Hovda, DA; Prins, ML	1
Amorini, AM; Barrios, L; Di Pietro, V; Marmarou, A; Marmarou, CR; Pascual, JM; Prieto, R; Tavazzi, B; Taya, K	1
Balakhadze, I; Eitzen, S; Fischer, B; Gorji, A; Greiner, C; Grimmelt, AC; Schiffbauer, H; Wölfer, J	1
Gay, M; Hallett, M; Horovitz, S; Johnson, B; Neuberger, T; Sebastianelli, W; Slobounov, S; Zhang, K	1
Geng, ZJ; Li, H; Li, JP; Lin, CG; Liu, XW; Mo, YX; Xie, CM; Zhang, R	1
Akhadov, TA; Lukovenkov, AV; Petryaykin, AV; Semenova, NA; Sidorin, SS; Varfolomeev, SD	1
Babb, JS; Gonen, O; Grossman, RI; Kirov, II; Lui, YW; Tal, A	1
Galloway, M; Ghoddoussi, F; Kepsel, A; Sajja, VS; VandeVord, P	1
Brinker, T; Samii, M; Schuhmann, MU; Skardelly, M; Stiller, D; Thomas, S	1
Beaumont, A; Bullock, R; Fatouros, P; Hoyle, R; Marmarou, A; Sawauchi, S; Signoretti, S; Young, H	1
Andrews, PJ; Easton, VJ; Macmillan, CS; Marshall, I; Wardlaw, JM; Wild, JM	1
Albayram, S; Aydin, S; Dashti, SG; Hanci, M; Kuday, C; Uzan, M	1
Budd, SL; Gillessen, T; Lipton, SA	1
Arlien-Søborg, P; Christensen, PB; Danielsen, ER; Thomsen, C	1
Bernarding, J; Brinker, T; Klinge, PM; Samii, A; Samii, M; Schuhmann, MU; Skardelly, M; Stiller, D	1
Amorini, AM; Dunbar, J; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R	1
Chaseling, R; Joy, P; Kemp, A; Parry, L; Rae, C; Shores, A; Waugh, MC	1
Guo, YW; Xu, RX	1
Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K	1
Holshouser, BA; Shutter, L; Tong, KA	1
Amorini, AM; Cimatti, M; Delfini, R; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R	1
Brooks, WM; Hunter, JV; Levin, HS; Roberson, G; Swank, PR; Thornton, RJ; Wang, ZJ	1
Ball, WS; Care, M; Cecil, KM; Makoroff, KL	1
Fauvage, B; Francony, G; Le Bas, JF; Payen, JF	1
Choe, BY; Choi, CB; Han, DY; Han, YM; Jeun, SS; Kang, YW; Kim, HY	1
Amorini, AM; Cimatti, M; Delfini, R; Donzelli, S; Lazzarino, G; Signoretti, S; Tavazzi, B; Vagnozzi, R	1
Abrahamson, EE; Ciallella, JR; Clark, RS; DeKosky, ST; Flood, DG; Hope, CE; Ikonomovic, MD; Isanski, BA; Paljug, WR	1
Amorini, AM; Belli, A; Bellia, F; Kitchen, N; Lazzarino, G; Petzold, A; Russo, S; Sen, J; Signoretti, S; Smith, M; Tavazzi, B; Vagnozzi, R	1
Berman, RF; Bzdega, T; Jiang, J; Kozikowski, AP; Lyeth, BG; Neale, JH; O'Connor, WT; Smyth, A; Van, KC; Zhao, X; Zhong, C; Zhou, J	1
Ashwal, S; Ghamsary, M; Holshouser, BA; Oyoyo, U; Saunders, D; Shutter, L; Tong, KA	1
Brooks, WM; Jung, RE; Yeo, RA	1
Chao, L; Laxer, K; Meyerhoff, DJ; Mueller, S; Sacrey, DT; Schuff, N; Weiner, MW	1
Barker, PB; Degaonkar, M; Earley, CJ; Halbower, AC; Mahone, EM; Marcus, CL; Prahme, MC; Smith, PL	1
Ashwal, S; Babikian, T; Burley, T; Freier, MC; Holshouser, BA; Riggs, ML	1
Brooks, WM; Brown, AJ; Campbell, RC; Jung, RE; Phillips, JP; Yeo, RA	1
Cimatti, M	1
Ashwal, S; Babikian, T; Freier, MC; Gardner-Nichols, J; Holshouser, BA; Tong, KA	1
Nakabayashi, M; Suzaki, S; Tomita, H	1
Babb, JS; Cohen, BA; Gonen, O; Grossman, RI; Inglese, M; Rusinek, H	1
Castillo, M	1
Barrios, L; Cerdán, S; López-Larrubia, P; Pascual, JM; Prieto, R; Roda, JM; Solivera, J	1
Babb, JS; Fleysher, L; Gonen, O; Grossman, RI; Kirov, I; Silver, JM	1
Aygok, GA; Bullock, RM; Fatouros, PP; Marmarou, A; Portella, G; Signoretti, S	1
Casey, PA; Fiskum, G; McKenna, MC; Robertson, CL; Saraswati, M	1
Botscheller, ML; DeKosky, ST; Marion, DW; Palmer, AM; Styren, SD; Swedlow, PE	1
Danielsen, ER; Michaelis, T; Ross, BD	1
Botscheller, ML; Marion, DW; Palmer, AM; Redd, EE	1
Inao, S; Kuchiwaki, H; Sugita, K; Yamamoto, M; Yoshida, K	1
Ashwal, S; Bailey, L; Hinshaw, DB; Holshouser, BA; Schell, RM	1
Ashwal, S; Auld, KL; Hinshaw, DB; Holshouser, BA; Kahlon, S; Luh, GY; Perkin, RM; Shu, S; Tomasi, LG	1
Hagberg, H; Puka-Sundvall, M; Sandberg, M	1
Barbarella, G; Basaglia, N; Boldrini, P; Musi, P; Ricci, R; Trevisan, C	1
Cecil, K; Lenkinski, RE; McIntosh, TK; Rubin, Y; Smith, DH; Wehrli, S	1
Aggarwal, N; Baethmann, A; Eriskat, J; Plesnila, M; Stoffel, M	1
Başkaya, MK; Dempsey, RJ; Doğan, A; Rao, VL; Rothstein, JD	1
Cecil, KM; Lenkinski, RE; McIntosh, TK; Meaney, DF; Smith, DH	1
Bagley, LJ; Cecil, KM; Grossman, RI; Hills, EC; Lenkinski, RE; Mannon, LJ; McIntosh, TK; Sandel, ME; Sinson, GP; Smith, DH	1
Cecil, KM; Chen, XH; Gennarelli, TA; Lenkinski, RE; McIntosh, TK; Meaney, DF; Smith, DH	1
Bullock, R; Choi, S; Doppenberg, EM; Koura, SS; Marmarou, A; Young, HF	1
Amorini, AM; Caruso, I; Di Pierro, D; Fazzina, G; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R	1
Al-Samsam, RH; Alessandri, B; Bullock, R	1
Blamire, AM; Cadoux-Hudson, TA; Garnett, MR; Rajagopalan, B; Styles, P	1
Barlow, MA; Brooks, WM; Friedman, SD; Jung, RE; Petropoulos, H; Sibbitt, WL; Stidley, CA; Weers, DC; Yeo, RA	1
Blamire, AM; Cadoux-Hudson, TA; Corkill, RG; Garnett, MR; Rajagopalan, B; Styles, P	1
al-Samsam, R; Alessandri, B; Bullock, RM; Corwin, F; Fatouros, P; Young, HF	1
Adelson, PD; Bell, MJ; Clark, RS; Graham, SH; Kochanek, PM; Marion, DW; Rose, ME; Ruppel, RA; Wisniewski, SR	1
Bagley, LJ; Cecil, KM; Grossman, RI; Lenkinski, RE; McGowan, JC; McIntosh, TK; Sinson, G; Torchia, M	1
Blamire, AM; Cadoux-Hudson, TA; Corkill, RG; Garnett, MR; Manners, DN; Rajagopalan, B; Styles, P; Young, JD	1
Arfai, N; Feeney, DM; Gasparovic, C; Smid, N	1
Goodman, JC; Gopinath, SP; Robertson, CS; Valadka, AB	1
Bard, C; Boulanger, Y; Khiat, A; Lacroix, A; Yared, Z	1
Babb, JS; Fowble, BL; Gonen, O; Li, BS; Movsas, B; Nicolaou, N	1
Bullock, R; Doppenberg, EM; Gilman, C; Menzel, M; Soukup, J; Young, HF; Zauner, A	1
Doi, M; Kubo, Y; Kudo, A; Ogasawara, K; Ogawa, A; Sugawara, A; Suzuki, M; Suzuki, T; Yoshida, K	1
Graham, SH; Huerbin, MB; Kochanek, PM; Marion, DW; Melick, J; Palmer, AM; Rose, ME; Schiding, JK	1
Olney, JW	1
Chang, LH; Cohen, Y; James, TL; Litt, L; Nishimura, MC; Pitts, LH; Sanada, T; Weinstein, PR	1
Demediuk, P; Faden, AI; Panter, SS; Vink, R	1
Simon, RP	1
Faden, AI; McIntosh, TK; Vink, R	1

Reviews

10 review(s) available for aspartic acid and Acute Brain Injuries

Article	Year
A systematic review of Magnetic Resonance Imaging and Spectroscopy in brain injury after drowning. Brain injury, 2009, Volume: 23, Issue:9 Topics: Aspartic Acid; Brain Injuries; Child; Child, Preschool; Drowning; Female; Humans; Hypoxia, Brain; Infant; Lactic Acid; Magnetic Resonance Spectroscopy; Male; United States	2009
Biochemical and neurochemical sequelae following mild traumatic brain injury: summary of experimental data and clinical implications. Neurosurgical focus, 2010, Volume: 29, Issue:5 Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Diffuse Axonal Injury; Disease Models, Animal; Humans; Magnetic Resonance Spectroscopy; Oxidative Stress; Rats	2010
Excitatory amino acid neurotoxicity. Advances in experimental medicine and biology, 2002, Volume: 513 Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Calcium; Epilepsy; Glutamic Acid; Humans; Mitochondria; Nervous System Diseases; Neurodegenerative Diseases; Reactive Nitrogen Species; Reactive Oxygen Species; Receptors, Glutamate; Signal Transduction	2002
[Contribution of magnetic resonance spectroscopy in predicting severity and outcome in traumatic brain injury]. Annales francaises d'anesthesie et de reanimation, 2005, Volume: 24, Issue:5 Topics: Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Injuries; Choline; Craniocerebral Trauma; Energy Metabolism; Glasgow Outcome Scale; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Animal; Prognosis; Rats; Wounds, Nonpenetrating	2005
NAA and higher cognitive function in humans. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Aspartic Acid; Brain; Brain Injuries; Cognition; Humans; Magnetic Resonance Spectroscopy	2006
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease. Advances in experimental medicine and biology, 2006, Volume: 576 Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cocaine; Creatine; Epilepsy; Ethanol; HIV Infections; Humans; Magnetic Resonance Imaging; Neurodegenerative Diseases; Neurons; Stress Disorders, Post-Traumatic	2006
Susceptibility-weighted imaging and proton magnetic resonance spectroscopy in assessment of outcome after pediatric traumatic brain injury. Archives of physical medicine and rehabilitation, 2006, Volume: 87, Issue:12 Suppl 2 Topics: Aspartic Acid; Axons; Brain Injuries; Child; Choline; Creatine; Humans; Imaging, Three-Dimensional; Injury Severity Score; Intracranial Hemorrhages; Magnetic Resonance Imaging; Neuropsychological Tests; Outcome Assessment, Health Care	2006
Whole-brain N-acetylaspartate: a marker of the severity of mild head trauma. AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:5 Topics: Aspartic Acid; Biomarkers; Brain Injuries; Humans; Magnetic Resonance Spectroscopy; Trauma Severity Indices	2007
Excitotoxin-mediated neuron death in youth and old age. Progress in brain research, 1990, Volume: 86 Topics: Aging; Alzheimer Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Calcium Channels; Cell Survival; Central Nervous System; Central Nervous System Diseases; Food; Food Additives; Glutamates; Glutamic Acid; Humans; Ion Channel Gating; Neurons; Neurotoxins; Rats; Receptors, N-Methyl-D-Aspartate	1990
Role of endogenous excitatory amino acid neurotransmitters in the pathogenesis and evolution of acute brain injury. The Pediatric infectious disease journal, 1989, Volume: 8, Issue:12 Topics: Acute Disease; Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Injuries; Calcium; Calcium Channels; Humans; Meningitis; N-Methylaspartate; Neurotransmitter Agents; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989

Trials

5 trial(s) available for aspartic acid and Acute Brain Injuries

Article	Year
An experimental study on acute brain radiation injury: dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology. European journal of radiology, 2012, Volume: 81, Issue:11 Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Magnetic Resonance Spectroscopy; Protons; Rabbits; Radiation Injuries, Experimental; Statistics as Topic	2012
Proton MR spectroscopy and MRI-volumetry in mild traumatic brain injury. AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:5 Topics: Adult; Age Factors; Aspartic Acid; Atrophy; Axons; Brain; Brain Injuries; Female; Glasgow Coma Scale; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Protons	2007
Assessment of mitochondrial impairment in traumatic brain injury using high-resolution proton magnetic resonance spectroscopy. Journal of neurosurgery, 2008, Volume: 108, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Follow-Up Studies; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondrial Diseases; Outcome Assessment, Health Care; Predictive Value of Tests; Time Factors	2008
Evidence for cellular damage in normal-appearing white matter correlates with injury severity in patients following traumatic brain injury: A magnetic resonance spectroscopy study. Brain : a journal of neurology, 2000, Volume: 123 ( Pt 7) Topics: Adolescent; Adult; Aged; Amnesia; Aspartic Acid; Axons; Brain Chemistry; Brain Injuries; Cerebral Cortex; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged	2000
Early proton magnetic resonance spectroscopy in normal-appearing brain correlates with outcome in patients following traumatic brain injury. Brain : a journal of neurology, 2000, Volume: 123 ( Pt 10) Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Choline; Creatine; Disability Evaluation; Female; Glasgow Outcome Scale; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Protons; Recovery of Function	2000

Other Studies

102 other study(ies) available for aspartic acid and Acute Brain Injuries

Article	Year
Replicability of proton MR spectroscopic imaging findings in mild traumatic brain injury: Implications for clinical applications. NeuroImage. Clinical, 2023, Volume: 37 Topics: Adult; Aspartic Acid; Brain; Brain Concussion; Brain Injuries; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Middle Aged; Proton Magnetic Resonance Spectroscopy; Protons; Young Adult	2023
Hemodialysis-Related Acute Brain Injury Demonstrated by Application of Intradialytic Magnetic Resonance Imaging and Spectroscopy. Journal of the American Society of Nephrology : JASN, 2023, 06-01, Volume: 34, Issue:6 Topics: Aged; Aspartic Acid; Brain; Brain Injuries; Choline; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Renal Dialysis; Spectrum Analysis; White Matter	2023
[Effect of aqueous extract of Corni Fructus on Aβ_(25-35)-induced brain injury and neuroinflammation in mice with Alzheimer's disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023, Volume: 48, Issue:15 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aspartic Acid; Brain Injuries; Cornus; Cysteine; Disease Models, Animal; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Docking Simulation; Neuroinflammatory Diseases; Peptide Hydrolases; Tumor Necrosis Factor-alpha	2023
Wu-zhu-yu Decoction reduces early brain injury following subarachnoid hemorrhage in vivo and in vitro by activating the Nrf2 antioxidant system via SIRT6 targeting. Journal of ethnopharmacology, 2024, Jan-30, Volume: 319, Issue:Pt 3 Topics: Animals; Antioxidants; Apoptosis; Aspartic Acid; Brain Injuries; Caspase 3; Hemoglobins; Neuroprotective Agents; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Sirtuins; Subarachnoid Hemorrhage	2024
Hippocampal changes in inflammasomes, apoptosis, and MEMRI after radiation-induced brain injury in juvenile rats. Radiation oncology (London, England), 2020, Apr-10, Volume: 15, Issue:1 Topics: Animals; Apoptosis; Aspartic Acid; Brain Injuries; Caspases; Creatine; Hippocampus; Inflammasomes; Magnetic Resonance Imaging; Male; Manganese Compounds; Radiation Dosage; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley	2020
Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury. Scientific reports, 2019, 02-04, Volume: 9, Issue:1 Topics: Aspartic Acid; Brain; Brain Injuries; Cerebellum; Choline; Creatine; Female; Gestational Age; Gray Matter; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pregnancy; Pregnancy Trimester, Third; Premature Birth; Proton Magnetic Resonance Spectroscopy	2019
Metabolic changes in patients with aneurysmal subarachnoid hemorrhage apart from perfusion deficits: neuronal mitochondrial injury? AJNR. American journal of neuroradiology, 2013, Volume: 34, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Cerebrovascular Disorders; Female; Glutamine; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Neurons; Protons; Subarachnoid Hemorrhage	2013
Impact of methamphetamine on regional metabolism and cerebral blood flow after traumatic brain injury. Neurocritical care, 2013, Volume: 19, Issue:2 Topics: Adolescent; Adult; Amphetamine-Related Disorders; Aspartic Acid; Brain; Brain Injuries; Central Nervous System Stimulants; Cerebrovascular Circulation; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methamphetamine; Middle Aged; Perfusion Imaging; Prospective Studies; Young Adult	2013
MRSI of the medial temporal lobe at 7 T in explosive blast mild traumatic brain injury. Magnetic resonance in medicine, 2014, Volume: 71, Issue:4 Topics: Adult; Aspartic Acid; Biomarkers; Blast Injuries; Brain Injuries; Choline; Creatine; Explosions; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Military Personnel; Molecular Imaging; Reproducibility of Results; Sensitivity and Specificity; Temporal Lobe; Tissue Distribution; United States	2014
Clinical correlations of proton magnetic resonance spectroscopy findings in acute phase after mild traumatic brain injury. Brain injury, 2014, Volume: 28, Issue:3 Topics: Adult; Aspartic Acid; Biomarkers; Brain Injuries; Cognition Disorders; Creatine; Female; Frontal Lobe; Glasgow Coma Scale; Humans; Male; Middle Aged; Neuropsychological Tests; Proton Magnetic Resonance Spectroscopy; Sensitivity and Specificity	2014
Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury. Neurology, 2014, Feb-11, Volume: 82, Issue:6 Topics: Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Caudate Nucleus; Choline; Corpus Striatum; Creatine; Female; Globus Pallidus; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Fibers, Unmyelinated; Putamen; Thalamus; Young Adult	2014
The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury. Molecular medicine (Cambridge, Mass.), 2014, Mar-24, Volume: 20 Topics: Acetyltransferases; Adenosine Diphosphate; Adenosine Triphosphate; Amidohydrolases; Animals; Aspartic Acid; Brain; Brain Injuries; Disease Models, Animal; Male; Mitochondria; Phosphorylation; Rats; Rats, Wistar	2014
Magnetic resonance spectroscopic imaging of brain injury after nasopharyngeal cancer radiation in early delayed reaction. Genetics and molecular research : GMR, 2014, Aug-29, Volume: 13, Issue:3 Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nasopharyngeal Neoplasms; Prognosis; Radiation Injuries; Radiotherapy; Time Factors	2014
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes. Traffic injury prevention, 2014, Volume: 15 Suppl 1 Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Swine; Swine, Miniature	2014
Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions. Experimental neurology, 2015, Volume: 267 Topics: Analysis of Variance; Animals; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Injuries; Cerebral Cortex; Cortical Spreading Depression; Disease Models, Animal; Electrophysiology; Excitatory Amino Acid Agents; Female; Glutamic Acid; Humans; Infarction, Middle Cerebral Artery; Male; Microelectrodes; Rats; Rats, Sprague-Dawley	2015
N-acetyl-aspartate levels correlate with intra-axonal compartment parameters from diffusion MRI. NeuroImage, 2015, Volume: 118 Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Female; Humans; Inositol; Male; Models, Neurological; Proton Magnetic Resonance Spectroscopy; White Matter	2015
Neuroprotective efficacy of decompressive craniectomy after controlled cortical impact injury in rats: An MRI study. Brain research, 2015, Oct-05, Volume: 1622 Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Choline; Creatine; Decompressive Craniectomy; Disease Models, Animal; Lactic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Random Allocation; Rats, Sprague-Dawley; Treatment Outcome	2015
Methamphetamine Induces Anhedonic-Like Behavior and Impairs Frontal Cortical Energetics in Mice. CNS neuroscience & therapeutics, 2017, Volume: 23, Issue:2 Topics: Anhedonia; Animals; Aspartic Acid; Brain Injuries; Central Nervous System Stimulants; Cerebral Cortex; Disease Models, Animal; Exploratory Behavior; Food Preferences; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Glutamic Acid; Grooming; Male; Maze Learning; Methamphetamine; Mice; Mice, Inbred C57BL; Motor Activity	2017
When are metabolic ratios superior to absolute quantification? A statistical analysis. NMR in biomedicine, 2017, Volume: 30, Issue:7 Topics: Adult; Algorithms; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Data Interpretation, Statistical; Female; Humans; Magnetic Resonance Spectroscopy; Male; Metabolic Flux Analysis; Middle Aged; Reproducibility of Results; Sensitivity and Specificity	2017
Distinct MRI pattern in lesional and perilesional area after traumatic brain injury in rat--11 months follow-up. Experimental neurology, 2009, Volume: 215, Issue:1 Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffusion Magnetic Resonance Imaging; Dipeptides; Disease Models, Animal; Follow-Up Studies; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Statistics, Nonparametric; Time Factors	2009
Brain injury in glutaric aciduria type I: the value of functional techniques in magnetic resonance imaging. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2009, Volume: 13, Issue:6 Topics: Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain; Brain Injuries; Brain Mapping; Creatine; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Infant; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Retrospective Studies	2009
Assessment of mitochondrial impairment and cerebral blood flow in severe brain injured patients. Acta neurochirurgica. Supplement, 2008, Volume: 102 Topics: Aspartic Acid; Blood Flow Velocity; Brain Injuries; Cerebrovascular Circulation; Diffusion Magnetic Resonance Imaging; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Spectroscopy; Mitochondrial Diseases; Protons; Regional Blood Flow	2008
Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats. Journal of neurochemistry, 2009, Volume: 109 Suppl 1 Topics: Amino Acids; Animals; Aspartic Acid; Brain Edema; Brain Injuries; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Nerve Tissue Proteins; Neurotransmitter Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley	2009
Proton spectroscopy in patients with post-traumatic headache attributed to mild head injury. Headache, 2009, Volume: 49, Issue:9 Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Brain Mapping; Cell Membrane; Choline; Chronic Disease; Craniocerebral Trauma; Female; Headache; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Severity of Illness Index; Young Adult	2009
Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat. Molecular and cellular biochemistry, 2010, Volume: 333, Issue:1-2 Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain Chemistry; Brain Injuries; Creatine; Energy Metabolism; Kinetics; Phosphates; Phosphocreatine; Rats	2010
Temporal and regional changes after focal traumatic brain injury. Journal of neurotrauma, 2010, Volume: 27, Issue:1 Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Brain Mapping; Cerebral Cortex; Choline; Creatine; Diffusion; Disease Models, Animal; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Time Factors	2010
Metabolic acetate therapy for the treatment of traumatic brain injury. Journal of neurotrauma, 2010, Volume: 27, Issue:1 Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Aspartic Acid; Brain; Brain Injuries; Disease Models, Animal; Energy Metabolism; Lipid Metabolism; Male; Membrane Lipids; Myelin Sheath; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome; Triacetin; Up-Regulation	2010
Evaluation of the late effects of CNS prophylactic treatment in childhood acute lymphoblastic leukemia (ALL) using magnetic resonance spectroscopy. Acta neurochirurgica. Supplement, 2010, Volume: 106 Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Child, Preschool; Choline; Cranial Irradiation; Creatine; Drug Administration Routes; Drug Therapy; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tissue Distribution	2010
Metabolic levels in the corpus callosum and their structural and behavioral correlates after moderate to severe pediatric TBI. Journal of neurotrauma, 2010, Volume: 27, Issue:3 Topics: Adolescent; Age Factors; Aging; Anisotropy; Aspartic Acid; Axons; Biomarkers; Brain Injuries; Child; Choline; Cognition Disorders; Corpus Callosum; Diffuse Axonal Injury; Diffusion Tensor Imaging; Female; Humans; Magnetic Resonance Spectroscopy; Male; Wallerian Degeneration	2010
Brain injury and recovery following binge ethanol: evidence from in vivo magnetic resonance spectroscopy. Biological psychiatry, 2010, May-01, Volume: 67, Issue:9 Topics: Alcoholism; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain Injuries; Brain Mapping; Central Nervous System Depressants; Cerebral Ventricles; Choline; Creatine; Ethanol; Hippocampus; Magnetic Resonance Spectroscopy; Male; Oxygen; Rats; Rats, Wistar; Recovery of Function; Statistics as Topic; Taurine; Time Factors	2010
Magnetic resonance spectroscopy predicts outcomes for children with nonaccidental trauma. Pediatrics, 2010, Volume: 125, Issue:2 Topics: Aspartic Acid; Brain Injuries; Cerebral Infarction; Child; Child, Preschool; Female; Glasgow Coma Scale; Humans; Lactates; Logistic Models; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Prognosis	2010
Whole-brain proton MR spectroscopic imaging of mild-to-moderate traumatic brain injury and correlation with neuropsychological deficits. Journal of neurotrauma, 2010, Volume: 27, Issue:3 Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cognition Disorders; Creatine; Diffuse Axonal Injury; Disability Evaluation; Female; Frontal Lobe; Glasgow Coma Scale; Humans; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Neuropsychological Tests; Wallerian Degeneration; Young Adult	2010
Neuroanatomical correlates of depression in post traumatic brain injury: preliminary results of a pilot study. The Journal of neuropsychiatry and clinical neurosciences, 2010,Spring, Volume: 22, Issue:2 Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Brain Injuries; Case-Control Studies; Choline; Cognition Disorders; Creatine; Depressive Disorder, Major; Frontal Lobe; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Neuropsychological Tests; Organ Size; Pilot Projects; Time Factors	2010
Limbic metabolic abnormalities in remote traumatic brain injury and correlation with psychiatric morbidity and social functioning. The Journal of neuropsychiatry and clinical neurosciences, 2010,Fall, Volume: 22, Issue:4 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Brain Mapping; Case-Control Studies; Choline; Female; Humans; Limbic System; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mental Disorders; Middle Aged; Social Adjustment; Statistics as Topic; Young Adult	2010
Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals. Journal of clinical and experimental neuropsychology, 2011, Volume: 33, Issue:3 Topics: Adult; Aspartic Acid; Brain Injuries; Cognition Disorders; Depression; Executive Function; Female; HIV Infections; Humans; Magnetic Resonance Spectroscopy; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Substance-Related Disorders	2011
Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury. Journal of neurotrauma, 2011, Volume: 28, Issue:9 Topics: 3-Hydroxybutyric Acid; Age Factors; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Diet, Ketogenic; Energy Metabolism; Magnetic Resonance Spectroscopy; Rats	2011
Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate. Brain research, 2011, Aug-02, Volume: 1404 Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Injuries; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Glutathione; Male; Models, Biological; NAD; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Lactate	2011
Closed traumatic brain injury model in sheep mimicking high-velocity, closed head trauma in humans. Central European neurosurgery, 2011, Volume: 72, Issue:3 Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Carbon Dioxide; Disease Models, Animal; Electron Spin Resonance Spectroscopy; gamma-Aminobutyric Acid; Glutamic Acid; Head Injuries, Closed; Humans; Image Processing, Computer-Assisted; Intracranial Pressure; Magnetic Resonance Imaging; Oxygen Consumption; Sheep; Sheep, Domestic	2011
Metabolic alterations in corpus callosum may compromise brain functional connectivity in MTBI patients: an 1H-MRS study. Neuroscience letters, 2012, Feb-10, Volume: 509, Issue:1 Topics: Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Corpus Callosum; Creatine; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Young Adult	2012
Metabolic dysfunction and relationship in human frontoparietal cortex in severe traumatic brain injury: single-voxel (1)H magnetic resonance spectroscopy study. Biochemistry. Biokhimiia, 2012, Volume: 77, Issue:4 Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine; Female; Humans; Inositol; Magnetic Resonance Imaging; Male; Radiography	2012
Diffuse axonal injury in mild traumatic brain injury: a 3D multivoxel proton MR spectroscopy study. Journal of neurology, 2013, Volume: 260, Issue:1 Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Brain Mapping; Choline; Creatine; Diffuse Axonal Injury; Female; Glasgow Coma Scale; Humans; Imaging, Three-Dimensional; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Protons; Young Adult	2013
Effects of blast-induced neurotrauma on the nucleus accumbens. Journal of neuroscience research, 2013, Volume: 91, Issue:4 Topics: Animals; Apoptosis; Aspartic Acid; bcl-2-Associated X Protein; Blast Injuries; Brain Injuries; Caspase 3; Glial Fibrillary Acidic Protein; Inflammation; Male; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Serotonin	2013
Long-time in-vivo metabolic monitoring following experimental brain contusion using proton magnetic resonance spectroscopy. Acta neurochirurgica. Supplement, 2002, Volume: 81 Topics: Animals; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Brain Injuries; Disease Models, Animal; Functional Laterality; Glutamic Acid; Hippocampus; Lactates; Magnetic Resonance Imaging; Male; Monitoring, Physiologic; Phosphocreatine; Rats; Rats, Sprague-Dawley; Reference Values; Taurine; Time Factors	2002
Application of chemical shift imaging for measurement of NAA in head injured patients. Acta neurochirurgica. Supplement, 2002, Volume: 81 Topics: Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatinine; Humans; Magnetic Resonance Imaging; Monitoring, Intraoperative; Neurochemistry; Reference Values; Time Factors; Treatment Outcome	2002
Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature. Acta neurochirurgica, 2002, Volume: 144, Issue:9 Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Child; Choline; Creatine; Critical Care; Diffuse Axonal Injury; Energy Metabolism; Female; Follow-Up Studies; Glasgow Coma Scale; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Subarachnoid Hemorrhage; Tomography, X-Ray Computed	2002
Thalamic proton magnetic resonance spectroscopy in vegetative state induced by traumatic brain injury. Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:1 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Child; Choline; Creatine; Diffuse Axonal Injury; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Persistent Vegetative State; Predictive Value of Tests; Protons; Recovery of Function; Reference Values; Thalamus	2003
Axonal recovery after severe traumatic brain injury demonstrated in vivo by 1H MR spectroscopy. Neuroradiology, 2003, Volume: 45, Issue:10 Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Cognition; Female; Humans; Magnetic Resonance Spectroscopy; Protons; Recovery of Function; Trauma Severity Indices	2003
Metabolic changes in the vicinity of brain contusions: a proton magnetic resonance spectroscopy and histology study. Journal of neurotrauma, 2003, Volume: 20, Issue:8 Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatine; Functional Laterality; Glutamic Acid; Immunohistochemistry; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Protons; Rats; Rats, Sprague-Dawley; Taurine; Time Factors	2003
The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury. Journal of neurotrauma, 2004, Volume: 21, Issue:9 Topics: Animals; Aspartic Acid; Brain Injuries; Cyclosporine; Drug Administration Schedule; Infusions, Intravenous; Injections, Spinal; Male; Mitochondria; Neuroprotective Agents; Rats; Rats, Sprague-Dawley	2004
An investigation of neuronal integrity in severe paediatric traumatic brain injury. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence, 2004, Volume: 10, Issue:4 Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Child; Choline; Cognition Disorders; Creatine; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Neurons; Neuropsychological Tests; Reaction Time; Reference Values; Severity of Illness Index; Statistics, Nonparametric	2004
[Detection of amino acid neurotransmitters in cerebrospinal fluid of patients in persistent vegetative state]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:1 Topics: Adolescent; Adult; Alanine; Aspartic Acid; Brain Injuries; Child; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Persistent Vegetative State	2005
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. Journal of neurotrauma, 2004, Volume: 21, Issue:11 Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Coma; Disease Progression; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Occipital Lobe; Parietal Lobe; Predictive Value of Tests; Recovery of Function; Up-Regulation	2004
Proton MRS in acute traumatic brain injury: role for glutamate/glutamine and choline for outcome prediction. Journal of neurotrauma, 2004, Volume: 21, Issue:12 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Cerebral Cortex; Choline; Creatinine; Evoked Potentials, Somatosensory; Female; Follow-Up Studies; Glasgow Outcome Scale; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Time Factors	2004
Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats. Neurosurgery, 2005, Volume: 56, Issue:3 Topics: Animals; Ascorbic Acid; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Energy Metabolism; Head Injuries, Closed; Hypotension; Hypoxia; Male; Malondialdehyde; NAD; NADP; Nucleosides; Oxidative Stress; Phosphates; Purines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2005
Late proton MR spectroscopy in children after traumatic brain injury: correlation with cognitive outcomes. AJNR. American journal of neuroradiology, 2005, Volume: 26, Issue:3 Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; Creatine; Dominance, Cerebral; Female; Frontal Lobe; Humans; Magnetic Resonance Spectroscopy; Male; Mathematics; Mental Processes; Osmolar Concentration; Wounds, Nonpenetrating	2005
Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury. Pediatric radiology, 2005, Volume: 35, Issue:7 Topics: Aspartic Acid; Brain Chemistry; Brain Injuries; Critical Care; Female; Fractures, Bone; Frontal Lobe; Glasgow Outcome Scale; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn; Lactic Acid; Length of Stay; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurologic Examination; Occipital Lobe; Parietal Lobe; Prospective Studies; Retinal Hemorrhage; Seizures	2005
In vivo 1H MR spectroscopic findings in traumatic contusion of ICR mouse brain induced by fluid percussion injury. European journal of radiology, 2005, Volume: 55, Issue:1 Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Creatine; Magnetic Resonance Spectroscopy; Male; Mice; Percussion; Signal Processing, Computer-Assisted	2005
Hypothesis of the postconcussive vulnerable brain: experimental evidence of its metabolic occurrence. Neurosurgery, 2005, Volume: 57, Issue:1 Topics: Adenosine Triphosphate; Animals; Apyrase; Aspartic Acid; Blood Gas Analysis; Brain; Brain Injuries; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Male; Rats; Rats, Wistar; Time Factors	2005
Caspase inhibition therapy abolishes brain trauma-induced increases in Abeta peptide: implications for clinical outcome. Experimental neurology, 2006, Volume: 197, Issue:2 Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Blotting, Western; Brain Injuries; Caspase 3; Caspase Inhibitors; Caspases; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Functional Laterality; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mice; Mice, Transgenic; Neural Inhibition; Peptide Fragments; Stilbamidines; Time Factors	2006
Extracellular N-acetylaspartate depletion in traumatic brain injury. Journal of neurochemistry, 2006, Volume: 96, Issue:3 Topics: Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Extracellular Space; Humans; Magnetic Resonance Spectroscopy; Microdialysis; Middle Aged; Postmortem Changes; Time Factors	2006
NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat. Journal of neurochemistry, 2006, Volume: 97, Issue:4 Topics: Animals; Aspartic Acid; Brain Injuries; Cytoprotection; Dipeptides; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamate Carboxypeptidase II; Glutamic Acid; Hippocampus; Male; Microdialysis; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Up-Regulation	2006
Prospective longitudinal proton magnetic resonance spectroscopic imaging in adult traumatic brain injury. Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:1 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Case-Control Studies; Corpus Callosum; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurology; Protons	2006
Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury. PLoS medicine, 2006, Volume: 3, Issue:8 Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Cerebral Cortex; Child; Choline; Cross-Sectional Studies; Demography; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Neurons; Neuropsychological Tests; Polysomnography; Radiography; Respiratory Function Tests; Sleep Apnea, Obstructive	2006
MR spectroscopy: predicting long-term neuropsychological outcome following pediatric TBI. Journal of magnetic resonance imaging : JMRI, 2006, Volume: 24, Issue:4 Topics: Adolescent; Aspartic Acid; Brain Injuries; Child; Child, Preschool; Creatine; Female; Glutamic Acid; Glutamine; Humans; Infant; Inositol; Linear Models; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Predictive Value of Tests; Recovery of Function; Statistics, Nonparametric	2006
Magnetic resonance spectroscopy detects brain injury and predicts cognitive functioning in children with brain injuries. Journal of neurotrauma, 2006, Volume: 23, Issue:10 Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Memory; Motor Activity	2006
Assessment of metabolic cerebral damage using proton magnetic resonance spectroscopy in mild traumatic brain injury. Journal of neurosurgical sciences, 2006, Volume: 50, Issue:4 Topics: Adult; Aspartic Acid; Boxing; Brain; Brain Injuries; Humans; Magnetic Resonance Spectroscopy; Male	2006
Neural injury and recovery near cortical contusions: a clinical magnetic resonance spectroscopy study. Journal of neurosurgery, 2007, Volume: 106, Issue:3 Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Longitudinal Studies; Magnetic Resonance Spectroscopy; Male; Middle Aged; Time Factors	2007
Time course of early metabolic changes following diffuse traumatic brain injury in rats as detected by (1)H NMR spectroscopy. Journal of neurotrauma, 2007, Volume: 24, Issue:6 Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Chemistry; Brain Injuries; Creatine; Diffuse Axonal Injury; Disease Models, Animal; Disease Progression; Inositol; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation; Water-Electrolyte Balance	2007
Characterizing 'mild' in traumatic brain injury with proton MR spectroscopy in the thalamus: Initial findings. Brain injury, 2007, Volume: 21, Issue:11 Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Thalamus; Trauma Severity Indices	2007
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats. Journal of neurotrauma, 2008, Volume: 25, Issue:6 Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; Choline; Creatine; Disease Progression; Energy Metabolism; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Nerve Degeneration; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors	2008
Traumatic brain injury-induced excitotoxicity assessed in a controlled cortical impact model. Journal of neurochemistry, 1993, Volume: 61, Issue:6 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Male; Microdialysis; Microinjections; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Serine	1993
Three methods of calibration in quantitative proton MR spectroscopy. Journal of magnetic resonance. Series B, 1995, Volume: 106, Issue:3 Topics: Adult; Aspartic Acid; Body Water; Brain; Brain Chemistry; Brain Injuries; Calibration; Choline; Creatine; Hepatic Encephalopathy; Humans; Inositol; Magnetic Resonance Spectroscopy; Models, Structural	1995
Therapeutic hypothermia is cytoprotective without attenuating the traumatic brain injury-induced elevations in interstitial concentrations of aspartate and glutamate. Journal of neurotrauma, 1993,Winter, Volume: 10, Issue:4 Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Histocytochemistry; Hypothermia, Induced; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence	1993
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury. Acta neurochirurgica. Supplementum, 1994, Volume: 60 Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats; Electroencephalography; Evoked Potentials; Freezing; Glutamic Acid; Methionine; Motor Cortex; Phenylalanine; Serine; Synaptic Transmission; Tyrosine; Valine	1994
Proton magnetic resonance spectroscopy in the evaluation of children with congenital heart disease and acute central nervous system injury. The Journal of thoracic and cardiovascular surgery, 1996, Volume: 112, Issue:2 Topics: Aspartic Acid; Brain; Brain Injuries; Cardiopulmonary Bypass; Case-Control Studies; Child, Preschool; Choline; Coma; Creatine; Follow-Up Studies; Forecasting; Glasgow Coma Scale; Heart Arrest; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Lactates; Magnetic Resonance Spectroscopy; Neurologic Examination; Patient Discharge; Phosphocreatine; Protons; Treatment Outcome	1996
Proton MR spectroscopy after acute central nervous system injury: outcome prediction in neonates, infants, and children. Radiology, 1997, Volume: 202, Issue:2 Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Brain Injuries; Child; Choline; Discriminant Analysis; Female; Humans; Infant; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Predictive Value of Tests; Prognosis	1997
Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine. Brain research, 1997, Mar-07, Volume: 750, Issue:1-2 Topics: Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Carotid Artery, Common; Cysteine; Excitatory Amino Acids; Extracellular Space; Factor Analysis, Statistical; Female; Glutamic Acid; Hypoxia, Brain; Ischemic Attack, Transient; Male; Microdialysis; Rats; Rats, Wistar; Reperfusion; Statistics, Nonparametric	1997
Localised proton MR spectroscopy of brain metabolism changes in vegetative patients. Neuroradiology, 1997, Volume: 39, Issue:5 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Persistent Vegetative State; Prognosis; Time Factors	1997
High-resolution 1H NMR spectroscopy following experimental brain trauma. Journal of neurotrauma, 1997, Volume: 14, Issue:7 Topics: Animals; Aspartic Acid; Brain Injuries; Disease Models, Animal; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Time Factors	1997
The penumbra zone of a traumatic cortical lesion: a microdialysis study of excitatory amino acid release. Acta neurochirurgica. Supplement, 1997, Volume: 70 Topics: Animals; Aspartic Acid; Brain Injuries; Excitatory Amino Acids; Glutamic Acid; Male; Microdialysis; Necrosis; Rats; Rats, Sprague-Dawley	1997
Traumatic brain injury down-regulates glial glutamate transporter (GLT-1 and GLAST) proteins in rat brain. Journal of neurochemistry, 1998, Volume: 70, Issue:5 Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Brain; Brain Injuries; Glucose Transporter Type 1; Male; Monosaccharide Transport Proteins; Neuroglia; Rats; Rats, Sprague-Dawley	1998
High-field proton magnetic resonance spectroscopy of a swine model for axonal injury. Journal of neurochemistry, 1998, Volume: 70, Issue:5 Topics: Animals; Aspartic Acid; Axons; Brain; Brain Injuries; Creatine; Disease Models, Animal; Female; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Sensitivity and Specificity; Swine; Swine, Miniature	1998
Proton magnetic resonance spectroscopy for detection of axonal injury in the splenium of the corpus callosum of brain-injured patients. Journal of neurosurgery, 1998, Volume: 88, Issue:5 Topics: Acceleration; Accidents, Traffic; Adult; Aged; Aspartic Acid; Axons; Brain Concussion; Brain Diseases; Brain Injuries; Cell Survival; Cerebral Hemorrhage; Cognition Disorders; Corpus Callosum; Creatine; Deceleration; Female; Hematoma, Epidural, Cranial; Hematoma, Subdural; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurons; Protons; Rotation; Stress, Mechanical	1998
Magnetic resonance spectroscopy of diffuse brain trauma in the pig. Journal of neurotrauma, 1998, Volume: 15, Issue:9 Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Axons; Behavior, Animal; Brain Chemistry; Brain Injuries; Female; Lactic Acid; Magnesium; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Phosphorus; Protons; Swine; Swine, Miniature	1998
Relationship between excitatory amino acid release and outcome after severe human head injury. Acta neurochirurgica. Supplement, 1998, Volume: 71 Topics: Animals; Aspartic Acid; Brain Damage, Chronic; Brain Injuries; Cerebral Cortex; Excitatory Amino Acids; Glasgow Coma Scale; Glutamic Acid; Humans; Microdialysis; Outcome Assessment, Health Care; Prognosis; Rats	1998
Ion-pairing high-performance liquid chromatographic method for the detection of N-acetylaspartate and N-acetylglutamate in cerebral tissue extracts. Analytical biochemistry, 2000, Jan-01, Volume: 277, Issue:1 Topics: Animals; Aspartic Acid; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Glutamates; Male; Rats; Rats, Wistar; Tissue Extracts	2000
Extracellular N-acetyl-aspartate as a biochemical marker of the severity of neuronal damage following experimental acute traumatic brain injury. Journal of neurotrauma, 2000, Volume: 17, Issue:1 Topics: Animals; Aspartic Acid; Biomarkers; Blood Gas Analysis; Blood Pressure; Brain; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Disease Models, Animal; Extracellular Space; Hydrogen-Ion Concentration; Hypotension; Hypoxia, Brain; Magnetic Resonance Imaging; Male; Neurons; Rats; Rats, Sprague-Dawley	2000
Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study. Journal of neurotrauma, 2000, Volume: 17, Issue:8 Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Choline; Cognition Disorders; Creatinine; Cross-Sectional Studies; Female; Humans; Inositol; Logistic Models; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Protons; Statistics, Nonparametric	2000
Acute and late changes in N-acetyl-aspartate following diffuse axonal injury in rats: an MRI spectroscopy and microdialysis study. Neurological research, 2000, Volume: 22, Issue:7 Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Diffuse Axonal Injury; Magnetic Resonance Imaging; Male; Microdialysis; Rats; Rats, Sprague-Dawley	2000
Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse. The Journal of pediatrics, 2001, Volume: 138, Issue:1 Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Brain Ischemia; Case-Control Studies; Cerebral Ventricles; Child; Child Abuse; Child, Preschool; Disabled Persons; Excitatory Amino Acids; Glasgow Coma Scale; Glasgow Outcome Scale; Glutamic Acid; Glycine; Humans; Infant; Prognosis; Survival Analysis; Time Factors; Tomography, X-Ray Computed	2001
Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: correlation with clinical outcome after traumatic brain injury. AJNR. American journal of neuroradiology, 2001, Volume: 22, Issue:1 Topics: Aspartic Acid; Axons; Biomarkers; Brain; Brain Injuries; Brain Stem; Corpus Callosum; Creatine; Glasgow Coma Scale; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Time Factors	2001
Altered cellular metabolism following traumatic brain injury: a magnetic resonance spectroscopy study. Journal of neurotrauma, 2001, Volume: 18, Issue:3 Topics: Adenosine Triphosphate; Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Choline; Creatine; Female; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphates; Phosphocreatine	2001
Decrease and recovery of N-acetylaspartate/creatine in rat brain remote from focal injury. Journal of neurotrauma, 2001, Volume: 18, Issue:3 Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Creatine; Magnetic Resonance Spectroscopy; Occipital Lobe; Rats; Rats, Sprague-Dawley	2001
Extracellular glutamate and aspartate in head injured patients. Acta neurochirurgica. Supplement, 2000, Volume: 76 Topics: Adolescent; Adult; Aspartic Acid; Brain Edema; Brain Injuries; Extracellular Space; Female; Glasgow Outcome Scale; Glutamic Acid; Humans; Male; Microdialysis; Middle Aged; Prognosis	2000
Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy. Brain research, 2001, Aug-24, Volume: 911, Issue:2 Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Injuries; Cell Membrane; Choline; Creatine; Cushing Syndrome; Drug Administration Schedule; Energy Metabolism; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Degeneration; Neurons; Prednisone	2001
Quantifying radiation therapy-induced brain injury with whole-brain proton MR spectroscopy: initial observations. Radiology, 2001, Volume: 221, Issue:2 Topics: Adult; Aged; Aspartic Acid; Brain Injuries; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mental Status Schedule; Middle Aged; Radiation Injuries	2001
Relationship between brain temperature, brain chemistry and oxygen delivery after severe human head injury: the effect of mild hypothermia. Neurological research, 2002, Volume: 24, Issue:2 Topics: Adolescent; Adult; Aged; Aspartic Acid; Body Temperature; Brain; Brain Chemistry; Brain Injuries; Carbon Dioxide; Extracellular Space; Glucose; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Hypothermia, Induced; Intracranial Hypertension; Lactic Acid; Microdialysis; Middle Aged; Oxygen Consumption; Treatment Outcome	2002
Amino acid concentrations in the blood of the jugular vein and peripheral artery after traumatic brain injury: decreased release of glutamate into the jugular vein in the early phase. Journal of neurotrauma, 2002, Volume: 19, Issue:2 Topics: Adolescent; Adult; Aged; Amino Acids; Arteries; Aspartic Acid; Brain Injuries; Cystine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Jugular Veins; Male; Middle Aged	2002
Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury. Brain research, 2002, May-10, Volume: 935, Issue:1-2 Topics: Animals; Aspartic Acid; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acids; Extracellular Space; Glucose; Glutamic Acid; Glycine; Hippocampus; Male; Microdialysis; Neurons; Rats; Rats, Sprague-Dawley; Sodium Channels; Up-Regulation	2002
Surface coil spectroscopic imaging: time and spatial evolution of lactate production following fluid percussion brain injury. Magnetic resonance in medicine, 1991, Volume: 17, Issue:1 Topics: Animals; Aspartic Acid; Brain Concussion; Brain Edema; Brain Injuries; Deuterium; Fourier Analysis; Lactates; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Time Factors	1991
The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science (New York, N.Y.), 1989, May-19, Volume: 244, Issue:4906 Topics: Animals; Aspartic Acid; Binding, Competitive; Brain; Brain Injuries; Dextrorphan; Glutamates; Glutamic Acid; Magnesium; Magnetic Resonance Spectroscopy; Male; N-Methylaspartate; Phosphates; Phosphocreatine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989
Nonedited 1H NMR lactate/n-acetyl aspartate ratios and the in vivo determination of lactate concentration in brain. Magnetic resonance in medicine, 1988, Volume: 7, Issue:1 Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Lactates; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains	1988