aspartic acid has been researched along with Acidosis in 28 studies
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
L-aspartic acid : The L-enantiomer of aspartic acid.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe two cases of typical essential tremor with aspartic acidemia and mildly increased concentrations of plasma glutamic acid." | 8.95 | Essential Tremor with Aspartic Acidemia. ( Fujioka, R; Miura, S; Taniwaki, T, 2017) |
| "We describe two cases of typical essential tremor with aspartic acidemia and mildly increased concentrations of plasma glutamic acid." | 4.95 | Essential Tremor with Aspartic Acidemia. ( Fujioka, R; Miura, S; Taniwaki, T, 2017) |
| "The relationship between acidosis and the metabolism of glutamine and glutamate was studied in cultured astrocytes." | 3.70 | Acidosis and astrocyte amino acid metabolism. ( Daikhin, Y; Nissim, I; Yudkoff, M, 2000) |
| " In acidosis there was a significantly higher flux through glutaminase and through glutamate, 2-oxoglutarate, succinate and malate dehydrogenases as well as markedly enhanced 13C-glucose formation." | 3.68 | Adaptation of renal tricarboxylic acid cycle metabolism to various acid-base states: study with [3-13C,5-15N]glutamine. ( Nissim, I; Yudkoff, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (60.71) | 18.7374 |
| 1990's | 5 (17.86) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, R | 1 |
| Kitazawa, K | 1 |
| Sanada, D | 1 |
| Kato, N | 1 |
| Ohkoshi, T | 1 |
| Katsumata, Y | 1 |
| Yamaguchi, S | 1 |
| Azzopardi, D | 1 |
| Robertson, NJ | 1 |
| Bainbridge, A | 1 |
| Cady, E | 1 |
| Charles-Edwards, G | 1 |
| Deierl, A | 1 |
| Fagiolo, G | 1 |
| Franks, NP | 1 |
| Griffiths, J | 1 |
| Hajnal, J | 1 |
| Juszczak, E | 1 |
| Kapetanakis, B | 1 |
| Linsell, L | 1 |
| Maze, M | 1 |
| Omar, O | 1 |
| Strohm, B | 1 |
| Tusor, N | 1 |
| Edwards, AD | 1 |
| Bhowmick, S | 1 |
| Moore, JT | 1 |
| Kirschner, DL | 1 |
| Drew, KL | 1 |
| Miura, S | 1 |
| Fujioka, R | 1 |
| Taniwaki, T | 1 |
| Xue, Y | 1 |
| Liao, SF | 1 |
| Son, KW | 1 |
| Greenwood, SL | 1 |
| McBride, BW | 1 |
| Boling, JA | 1 |
| Matthews, JC | 1 |
| PILKINGTON, LA | 1 |
| WELCH, J | 1 |
| PITTS, RF | 2 |
| Kovacevic, Z | 1 |
| McGivan, JD | 1 |
| Bogusky, RT | 1 |
| Steele, K | 1 |
| Lowenstein, LM | 1 |
| Nissim, I | 6 |
| Cattano, C | 1 |
| Lin, Z | 1 |
| Mu, X | 1 |
| Welbourne, T | 1 |
| Gotoh, M | 1 |
| Davies, SE | 1 |
| Obrenovitch, TP | 1 |
| Atlante, A | 1 |
| Gagliardi, S | 1 |
| Passarella, S | 1 |
| Yudkoff, M | 2 |
| Daikhin, Y | 1 |
| Heidenreich, O | 1 |
| Beckers, G | 1 |
| Bennett, FI | 1 |
| Alleyne, GA | 2 |
| Kean, EA | 1 |
| Vinay, P | 1 |
| Lemieux, G | 1 |
| Gougoux, A | 1 |
| Halperin, M | 1 |
| Kühn, P | 1 |
| Koller, H | 1 |
| Kohn, P | 1 |
| Holzhey, P | 1 |
| Sauer, F | 2 |
| Sarkar, NK | 1 |
| Holub, P | 1 |
| Weiss, M | 1 |
| Inczinger, F | 1 |
| Gleichmann, U | 1 |
| Bergman, EN | 1 |
| Kaufman, CF | 1 |
| Wolff, JE | 1 |
| Williams, HH | 1 |
| List, WF | 1 |
| Dunkl, H | 1 |
| Kraft-Kinz, J | 1 |
| Erfle, JD | 1 |
| Binns, MR | 1 |
| Christophe, J | 1 |
| Winand, J | 1 |
| Kutzner, R | 1 |
| Hebbelinck, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal Asphyxia[NCT00934700] | 92 participants (Actual) | Interventional | 2012-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Fractional anisotropy (FA) is a measure of tissue integrity in white matter tracts measured by diffusion tensor MRI, and it has been used in work in animals to assess potential neuroprotectants and can be used to predict subsequent neurological outcomes after birth asphyxia, including in infants treated with moderate hypothermia.~It is a scalar value between 0-1 that describe anisotropy of a diffusion process. A value of zero means that diffusion is unrestricted (or equally restricted) in all directions. A value of one means that diffusion occurs only along one axis and is fully restricted along all other directions or similar.~Fractional anisotropy data were extracted froma mask of the posterior limb of the internal capsule via tract-based spatial statistics. *Coefficient of variation=√(exp(var)-1), where var is the variance on the log scale" (NCT00934700)
Timeframe: 10 days
| Intervention | units on a scale (Mean) |
|---|---|
| Combination of Hypothermia and Xenon | 0.40 |
| Hypothermia and Standard Intensive Care | 0.40 |
Cerebral Lac/NAA ratio measured by magnetic resonance spectroscopy in patents (NCT00934700)
Timeframe: 10 days
| Intervention | ratio (Geometric Mean) |
|---|---|
| Combination of Hypothermia and Xenon | 0.25 |
| Hypothermia and Standard Intensive Care | 0.28 |
3 reviews available for aspartic acid and Acidosis
| Article | Year |
|---|---|
Essential Tremor with Aspartic Acidemia.
Topics: Acidosis; Adult; Aged; Aspartic Acid; Biomarkers; Essential Tremor; Female; Glutamic Acid; Humans; M | 2017 |
Mitochondrial metabolism of glutamine and glutamate and its physiological significance.
Topics: Acidosis; Animals; Aspartate Aminotransferases; Aspartic Acid; Brain; Cells, Cultured; Energy Metabo | 1983 |
Regulation of glutamine metabolism in dog kidney in vivo.
Topics: Acid-Base Equilibrium; Acidosis; Adenosine Triphosphate; Alanine; Ammonia; Animals; Aspartic Acid; B | 1986 |
2 trials available for aspartic acid and Acidosis
| Article | Year |
|---|---|
Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial.
Topics: Acidosis; Anesthetics, Inhalation; Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Combined Modalit | 2016 |
[Metabolic changes during anesthesia in intracardial operations].
Topics: Acid-Base Equilibrium; Acidosis; Anesthesia; Aspartic Acid; Benperidol; Blood Circulation; Child; Du | 1969 |
23 other studies available for aspartic acid and Acidosis
| Article | Year |
|---|---|
Diffuse Leukoencephalopathy Associated with Dialysis Disequilibrium Syndrome.
Topics: Acidosis; Aspartic Acid; Coma; Female; Humans; Leukoencephalopathies; Magnetic Resonance Imaging; Ma | 2015 |
Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernation season even when not hibernating and after ATP depletion, acidosis, and glutamate efflux.
Topics: Acidosis; Adenosine Triphosphate; Animals; Aspartic Acid; Cell Death; Glucose; Glutamic Acid; Hibern | 2017 |
Metabolic acidosis in sheep alters expression of renal and skeletal muscle amino acid enzymes and transporters.
Topics: Acidosis; Amino Acid Transport Systems; Amino Acids; Animals; Aspartate Aminotransferases; Aspartic | 2010 |
RELATIONSHIP OF PNH3 OF TUBULAR CELLS TO RENAL PRODUCTION OF AMMONIA.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Body Fluids; Dog | 1965 |
Glucose and ammonia formation in extracts of rat kidney cortex.
Topics: Acidosis; Ammonia; Animals; Aspartic Acid; Cytosol; Gluconeogenesis; Glucose; Hypokalemia; Kidney Co | 1982 |
Acid-base regulation of hepatic glutamine metabolism and ureagenesis: study with 15N.
Topics: Acid-Base Equilibrium; Acidosis; Alanine; Alkalosis; Ammonia; Animals; Aspartic Acid; Glutamine; In | 1993 |
Response of LLC-PK1-F+ cells to metabolic acidosis.
Topics: Acidosis; Animals; Aspartic Acid; Bicarbonates; Biological Transport; gamma-Glutamyltransferase; Glu | 1996 |
Brain tissue acidosis: effects on the extracellular concentration of N-acetylaspartate.
Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Ammonium Chloride; Animals; Aspartic Acid; Brain; Electr | 1997 |
Fumarate permeation in normal and acidotic rat kidney mitochondria: fumarate/malate and fumarate/aspartate translocators.
Topics: Acidosis; Adenylosuccinate Lyase; Animals; Aspartic Acid; Biological Transport; Carrier Proteins; Fu | 1998 |
Acidosis and astrocyte amino acid metabolism.
Topics: Acidosis; Amino Acids; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Glutamic Acid; Glutamine | 2000 |
[The effect of potassium chloride and organic potassium salts on the acid-base equilibrium in normo and hypokalemic rats].
Topics: Acetates; Acid-Base Equilibrium; Acidosis; Alkalosis; Animals; Aspartic Acid; Hypokalemia; Infusions | 1975 |
Gluconeogenesis and ammoniagenesis in rat kidney: effect of 3-mercaptopicolinic acid.
Topics: Acidosis; Ammonia; Animals; Aspartic Acid; Biological Transport, Active; Blood Glucose; Gluconeogene | 1976 |
Adaptation of renal tricarboxylic acid cycle metabolism to various acid-base states: study with [3-13C,5-15N]glutamine.
Topics: Acid-Base Imbalance; Acidosis; Adaptation, Physiological; Alkalosis; Ammonia; Animals; Aspartic Acid | 1991 |
Commentary on a review on the mechanism of ackee-induced vomiting sickness.
Topics: Acidosis; Aspartic Acid; Cyclopropanes; Glutamates; Glutamic Acid; Humans; Hypoglycins; Plant Poison | 1988 |
[Arrhythmias in acute myocardial infarct].
Topics: Acidosis; Acute Disease; Arrhythmias, Cardiac; Aspartic Acid; Atrial Fibrillation; Atrial Flutter; B | 1973 |
The lethal effect of ethionine administered to guinea pigs.
Topics: Acetoacetates; Acidosis; Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspartic Acid; Blood | 1967 |
[Effect of Cardilan Spofa (K and Mg asparaginate) on the acid-base equilibrium during experimental isoprenaline lesions of the myocardium].
Topics: Acid-Base Equilibrium; Acidosis; Animals; Aspartic Acid; Cardiomyopathies; Heart; Isoproterenol; Mag | 1974 |
[Postoperative electrolyte and water balance after mitral valve replacement].
Topics: Acidosis; Aspartic Acid; Extracorporeal Circulation; Heart; Heart Valve Prosthesis; Humans; Hyperald | 1972 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulli | 1974 |
Renal metabolic response to acid-base changes. II. The early effects of metabolic acidosis on renal metabolism in the rat.
Topics: Acidosis; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Carbohydrates; Gluconeogenesis; Ketogl | 1970 |
Turnover rates and intracellular pool size distribution of citrate cycle intermediates in normal, diabetic and fat-fed rats estimated by computer analysis from specific activity decay data of 14C-labeled citrate cycle acids.
Topics: Acetates; Acetoacetates; Acidosis; Animals; Aspartic Acid; Carbon Isotopes; Carnitine; Chromatograph | 1970 |
Metabolism of amino acids by the perfused rat kidney.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Glucose; Glutamates; Glutamine; Gly | 1971 |
Amino acid levels in plasma, liver, muscle, and kidney during and after exercise in fasted and fed rats.
Topics: Acidosis; Alanine; Amino Acids; Animals; Aspartic Acid; Fasting; Gluconeogenesis; Glutamates; Glutam | 1971 |