aspartic acid has been researched along with Ache in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (26.32) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 17 (44.74) | 29.6817 |
| 2010's | 8 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrés, E; Fayed, N; Garcia-Campayo, J; Modrego, PJ; Viguera, L | 1 |
| De Lange, FP; Geurts, DEM; Knoop, H; Roelofs, K; Schmits, IC; Toni, I; van der Meer, JWM; van der Schaaf, ME | 1 |
| Clemente, FR; Somers, DL | 1 |
| Geisslinger, G; Kettner, M; Lötsch, J; Oertel, BG; Renné, C; Roskam, B; Schmidt, PH; Scholich, K | 1 |
| Hernández, L; Páez, X; Quiñones, B; Silva, E | 1 |
| Radhakrishnan, R; Sluka, KA | 1 |
| Erdtel, M; Gussew, A; Kaiser, WA; Mentzel, HJ; Reichenbach, JR; Rzanny, R; Scholle, HC | 1 |
| Andres, E; Andrés-Bergareche, H; Beltrán, J; Fayed, N; Garcia-Campayo, J; Luciano, JV; Magallón, R | 1 |
| Dasilva, D; Freedman, SD; Fregni, F; Lenkinski, RE; Pascual-Leone, A; Potvin, K; Wang, X | 1 |
| Binkert, CA; Brügger, M; Ettlin, DA; Froehlich, JM; Graf, N; Gutzeit, A; Meier, D; Meier, ML; von Weymarn, C | 1 |
| Guan, X; Lu, W; Petralia, RS; Rothstein, JD; Tao, YX; Yaster, M | 1 |
| Constandil, L; Hernández, A; Laurido, C; Pelissier, T | 1 |
| Bai, ZT; Chen, B; Ji, YH; Shen, J; Zhang, JW; Zhang, XY | 1 |
| Apkarian, AV; Fredrickson, BE; Grachev, ID | 1 |
| Chang, YC; Cherng, CH; Tao, PL; Wang, JJ; Wen, ZH; Wong, CS | 1 |
| Dmitrieva, N; Hernández, L; Pérez, J; Rodríguez-Malaver, AJ | 1 |
| Binns, BC; Chu, Y; Johns, RA; Liaw, WJ; Rothstein, JD; Sepkuty, JP; Stephens, RL; Tao, YX | 1 |
| Fujita, T; Jin, YH; Nishioka, H; Wakabayashi, K; Yonehara, N | 1 |
| Hernández, L; Silva, E | 1 |
| Siddall, PJ; Sorensen, L; Trenell, MI; Yue, DK | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Ekblom, A; Ekman-Ordeberg, G; Irestedt, L; Nyberg, F; Olofsson, C; Ungerstedt, U; Wiklund, P | 1 |
| Cheng, JK; Lin, CR; Marsala, M; Tsai, PS; Wen, GH; Yang, LC | 1 |
| Ito, S; Matsumura, S; Minami, T; Mishina, M; Mori, H; Okuda-Ashitaka, E; Sakimura, K; Shimamoto, K | 1 |
| Apkarian, AV; Fredickson, BE; Grachev, ID | 1 |
| Freund, N; Gonzalez, LE; Hernandez, L; Quiñones, B; Silva, E | 1 |
| Grachev, ID; Ramachandran, TS; Thomas, PS | 1 |
| Hodkewitsch, E; Saurugg, D | 1 |
| Argyropoulos, G; Clarici, G; Heppner, F | 1 |
| Gebhart, GF; Sherman, AD | 1 |
| Larson, AA; Skilling, SR; Smullin, DH | 1 |
| DeLander, GE; Wahl, JJ | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Jacquet, YF | 1 |
| Elekes, I; Láng, T; Palkovits, M; Patthy, A | 1 |
| Raigorodsky, G; Urca, G | 1 |
| Caudle, RM; Isaac, L | 1 |
| Krüger, K | 1 |
3 trial(s) available for aspartic acid and Ache
| Article | Year |
|---|---|
Clinical effects and brain metabolic correlates in non-invasive cortical neuromodulation for visceral pain.
Topics: Adult; Analgesia; Aspartic Acid; Brain; Chronic Disease; Female; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pain; Pain Management; Pancreatitis, Chronic; Radionuclide Imaging; Severity of Illness Index; Somatosensory Cortex; Transcranial Magnetic Stimulation; Treatment Outcome | 2011 |
Brain chemistry reflects dual states of pain and anxiety in chronic low back pain.
Topics: Adult; Anxiety; Aspartic Acid; Biomarkers; Brain Chemistry; Female; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Low Back Pain; Magnetic Resonance Imaging; Male; Middle Aged; Pain; Pain Measurement; Thalamus | 2002 |
[Clinical experiences with an analgesic-acting infusion solution in neurological painful conditions].
Topics: Arthritis, Rheumatoid; Aspartic Acid; Dipyrone; Facial Neuralgia; Humans; Injections, Intravenous; Migraine Disorders; Nervous System Diseases; Pain; Pyridoxine; Reflex Sympathetic Dystrophy; Solutions | 1977 |
35 other study(ies) available for aspartic acid and Ache
| Article | Year |
|---|---|
Higher glutamate+glutamine and reduction of N-acetylaspartate in posterior cingulate according to age range in patients with cognitive impairment and/or pain.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aspartic Acid; Case-Control Studies; Cognition Disorders; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pain; Prospective Studies | 2014 |
Prefrontal Structure Varies as a Function of Pain Symptoms in Chronic Fatigue Syndrome.
Topics: Adolescent; Adult; Aspartic Acid; Creatine; Fatigue Syndrome, Chronic; Female; Glutamates; Gray Matter; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Middle Aged; Pain; Prefrontal Cortex; Severity of Illness Index; Young Adult | 2017 |
Contralateral high or a combination of high- and low-frequency transcutaneous electrical nerve stimulation reduces mechanical allodynia and alters dorsal horn neurotransmitter content in neuropathic rats.
Topics: Acupuncture Points; Amino Acids; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurotransmitter Agents; Pain; Pain Management; Pain Measurement; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Transcutaneous Electric Nerve Stimulation | 2009 |
A common human micro-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain.
Topics: Alleles; Amino Acid Substitution; Analgesics, Opioid; Asparagine; Aspartic Acid; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression Regulation; Homozygote; Humans; Pain; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Receptors, Opioid, mu; Somatosensory Cortex; Thalamus | 2009 |
[Effect of a simple morphine system injection in some aminoacids in the anterior cingulate cortex during acute pain].
Topics: Acute Disease; Amino Acids; Analgesics, Opioid; Animals; Arginine; Aspartic Acid; Cerebral Cortex; Disinfectants; Formaldehyde; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Male; Microdialysis; Morphine; Pain; Rats; Rats, Wistar | 2008 |
Increased glutamate and decreased glycine release in the rostral ventromedial medulla during induction of a pre-clinical model of chronic widespread muscle pain.
Topics: Acids; Analysis of Variance; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutamic Acid; Glycine; Male; Medulla Oblongata; Microdialysis; Muscle, Skeletal; Pain; Rats; Rats, Sprague-Dawley; Sensory System Agents; Sodium Chloride | 2009 |
Time-resolved functional 1H MR spectroscopic detection of glutamate concentration changes in the brain during acute heat pain stimulation.
Topics: Acute Disease; Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Glutamic Acid; Hot Temperature; Humans; Magnetic Resonance Spectroscopy; Male; Pain; Periodicity; Physical Stimulation; Protons; Time Factors | 2010 |
Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate.
Topics: Adult; Aspartic Acid; Brain; Cholic Acid; Cross-Sectional Studies; Diffusion Tensor Imaging; Female; Fibromyalgia; Glutamic Acid; Glutamine; Hippocampus; Humans; Inositol; Male; Middle Aged; Motor Cortex; Nuclear Magnetic Resonance, Biomolecular; Pain; Protons; Somatosensory Cortex | 2010 |
Insula-specific responses induced by dental pain. A proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Cerebral Cortex; Electrodes; Female; Glutamic Acid; Glutamine; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; Middle Aged; Models, Anatomic; Neurotransmitter Agents; Pain; Prospective Studies; Protons; Tooth Diseases; Trigeminal Nerve | 2011 |
Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Disease Models, Animal; Formaldehyde; Freund's Adjuvant; Glutamic Acid; Inflammation; Kainic Acid; Male; Nicotinic Acids; Pain; Phosphoserine; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2011 |
Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model.
Topics: Animals; Arthritis; Aspartic Acid; Disease Models, Animal; Enzyme Inhibitors; Pain; Racemases and Epimerases; Rats; Serine | 2012 |
Dynamic determination and possible mechanism of amino acid transmitter release from rat spinal dorsal horn induced by the venom and a neurotoxin (BmK I) of scorpion Buthus martensi Karsch.
Topics: Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Neurotransmitter Agents; Nociceptors; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Scorpion Venoms | 2002 |
Increasing of intrathecal CSF excitatory amino acids concentration following morphine challenge in morphine-tolerant rats.
Topics: Analgesics, Opioid; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Injections, Spinal; Male; Microdialysis; Morphine; Pain; Pain Measurement; Rats; Rats, Wistar; Time Factors | 2004 |
Differential release of neurotransmitters from superficial and deep layers of the dorsal horn in response to acute noxious stimulation and inflammation of the rat paw.
Topics: Afferent Pathways; Animals; Arginine; Aspartic Acid; Chondrus; Extracellular Fluid; Foot; gamma-Aminobutyric Acid; Glutamic Acid; Inflammation; Male; Microdialysis; Neurotransmitter Agents; Pain; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Wistar; Reaction Time; Synaptic Transmission; Up-Regulation | 2004 |
Spinal glutamate uptake is critical for maintaining normal sensory transmission in rat spinal cord.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamic Acid; Male; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission | 2005 |
Effect of morphine on the release of excitatory amino acids in the rat hind instep: Pain is modulated by the interaction between the peripheral opioid and glutamate systems.
Topics: Analgesics, Opioid; Animals; Aspartic Acid; Capsaicin; Disease Models, Animal; Drug Interactions; Electric Stimulation; Glutamic Acid; Hot Temperature; Male; Morphine; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Neural Conduction; Nociceptors; Opioid Peptides; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Opioid; Sensory Receptor Cells; Signal Transduction | 2006 |
[Extracellular aminoacids in the amygdala and nucleus accumbens in the rat during acute pain].
Topics: Acute Disease; Amygdala; Animals; Arginine; Aspartic Acid; Glutamic Acid; Male; Nucleus Accumbens; Pain; Rats; Rats, Wistar | 2007 |
Differences in metabolites in pain-processing brain regions in patients with diabetes and painful neuropathy.
Topics: Adult; Aged; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Diabetic Neuropathies; Female; Frontal Lobe; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pain; Reference Values; Sensory Thresholds; Thalamus | 2008 |
Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats.
Topics: Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Dinoprostone; Formaldehyde; Glutamic Acid; Hindlimb; Ibuprofen; Injections, Spinal; Male; Microdialysis; Pain; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 1995 |
Increased cerebrospinal fluid concentration of aspartate but decreased concentration of nitric oxide breakdown products in women experiencing visceral pain during active labour.
Topics: Adult; Aged; Analgesia; Aspartic Acid; Cesarean Section; Delivery, Obstetric; Enkephalin, Methionine; Female; Humans; Labor, Obstetric; Metalloendopeptidases; Middle Aged; Nitric Oxide; Pain; Postmenopause; Pregnancy; Reference Values; Substance P | 1997 |
Intrathecal magnesium sulfate attenuates algogenic behavior and spinal amino acids release after kainic acid receptor activation in rats.
Topics: Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Calcium Channel Blockers; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Kainic Acid; Magnesium Sulfate; Male; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Taurine | 2001 |
Characterization of the glutamatergic system for induction and maintenance of allodynia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; ATP-Binding Cassette Transporters; Capsaicin; Dinoprost; Dinoprostone; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Pain; Pain Measurement; Physical Stimulation; Posterior Horn Cells; Receptors, Glutamate; Synapses; Synaptic Transmission; Touch | 2001 |
Dissociating anxiety from pain: mapping the neuronal marker N-acetyl aspartate to perception distinguishes closely interrelated characteristics of chronic pain.
Topics: Anxiety; Aspartic Acid; Brain Chemistry; Brain Mapping; Chronic Disease; Humans; Neurons; Pain | 2001 |
Extracellular glutamate, aspartate and arginine increase in the ventral posterolateral thalamic nucleus during nociceptive stimulation.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Electrophoresis, Capillary; Extracellular Space; Glutamic Acid; Male; Microdialysis; Nociceptors; Pain; Pain Measurement; Rats; Rats, Wistar; Synaptic Transmission; Ventral Thalamic Nuclei | 2001 |
Decreased levels of N-acetylaspartate in dorsolateral prefrontal cortex in a case of intractable severe sympathetically mediated chronic pain (complex regional pain syndrome, type I).
Topics: Adult; Anxiety Disorders; Aspartic Acid; Chronic Disease; Depressive Disorder, Major; Female; Humans; Magnetic Resonance Imaging; Pain; Pain Measurement; Prefrontal Cortex | 2002 |
[Infusion therapy of pain in a series of neurological-neurosurgical patients].
Topics: Analgesics; Aspartic Acid; Dipyrone; Drug Combinations; Female; Humans; Magnesium; Male; Orphenadrine; Pain; Postoperative Complications; Potassium | 1976 |
Morphine and pain: effects on aspartate, GABA and glutamate in four discrete areas of mouse brain.
Topics: Aminobutyrates; Animals; Aspartic Acid; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Hypothalamus; Male; Mice; Morphine; Naloxone; Pain; Reticular Formation; Stress, Physiological | 1976 |
Interactions between substance P, calcitonin gene-related peptide, taurine and excitatory amino acids in the spinal cord.
Topics: Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Interactions; Glutamates; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Pain; Pain Measurement; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Self Mutilation; Spinal Cord; Substance P; Taurine | 1990 |
Behavior induced by putative nociceptive neurotransmitters is inhibited by adenosine or adenosine analogs coadministered intrathecally.
Topics: Adenosine; Animals; Aspartic Acid; Behavior, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Spinal; Male; Mice; N-Methylaspartate; Neurotransmitter Agents; Pain; Substance P | 1988 |
Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists.
Topics: Animals; Aspartic Acid; Enkephalins; Hot Temperature; Kainic Acid; Male; Mice; N-Methylaspartate; Narcotics; Nociceptors; Oxadiazoles; Pain; Phencyclidine; Phentolamine; Quisqualic Acid; Receptors, Opioid; Receptors, sigma; Spinal Cord | 1987 |
The NMDA receptor: central role in pain inhibition in rat periaqueductal gray.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Analgesia; Animals; Aspartic Acid; Kainic Acid; Male; Morphine; N-Methylaspartate; Oxadiazoles; Pain; Periaqueductal Gray; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
Distribution and stress-induced increase of glutamate and aspartate levels in discrete brain nuclei of rats.
Topics: Animals; Aspartic Acid; Brain Chemistry; Dextroamphetamine; Glutamates; Glutamic Acid; Male; Pain; Rats; Stress, Physiological | 1986 |
Intrathecal N-methyl-D-aspartate (NMDA) activates both nociceptive and antinociceptive systems.
Topics: 2-Amino-5-phosphonovalerate; Analgesia; Animals; Aspartic Acid; Behavior, Animal; Decerebrate State; Injections, Spinal; Male; N-Methylaspartate; Nociceptors; Pain; Rats; Valine | 1987 |
A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Aspartic Acid; Atropine; Binding, Competitive; Dipeptides; Dynorphins; Hot Temperature; Kinetics; Male; N-Methylaspartate; Pain; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
[Metabolic therapeutic possibilities of ischemic heart disease].
Topics: Angina Pectoris; Aspartic Acid; Coronary Disease; Electrocardiography; Female; Humans; Hypertension; Magnesium; Male; Middle Aged; Myocardium; Nitroglycerin; Pain; Potassium; Prenylamine | 1967 |