aspartic acid has been researched along with Absence Seizure in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (56.12) | 18.7374 |
| 1990's | 39 (19.90) | 18.2507 |
| 2000's | 25 (12.76) | 29.6817 |
| 2010's | 17 (8.67) | 24.3611 |
| 2020's | 5 (2.55) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, Q; Liu, L; Su, X; Tan, Q; Wan, X; Wang, W; Yang, X; Yue, Q; Zhang, S | 1 |
| Alexandre-Ribeiro, SR; Bernardi, MM; Bondan, EF; Coque, AC; Flório, JC; Garcia-Gomes, MSA; Gonçalves, FB; Kirsten, TB; Lebrun, I; Massironi, SMG; Mori, CMC; Sandini, TM; Silva-Sampaio, AC | 1 |
| Jiang, Z; Lin, Y; Zhao, C | 1 |
| Bikkamane Jayadev, N; Chang, JC; Hu, HH; Kodibagkar, VD; Vidya Shankar, R | 1 |
| Asadollahi, M; Raminfard, S; Roozbeh, M; Rostami, M; Ryan, F; Simani, L | 1 |
| Abe, M; Hirose, Y; Inamasu, J; Kumon, M; Kuwahara, K; Murayama, K; Nakae, S; Ohba, S; Sasaki, H; Yamada, S | 1 |
| Fujita, A; Hosoda, K; Kohmura, E; Kohta, M; Nagashima, H; Sasayama, T; Tanaka, J; Tanaka, K | 1 |
| Bisulli, F; Ferri, L; Gramegna, LL; Licchetta, L; Lodi, R; Naldi, I; Rizzo, G; Testa, C; Tinuper, P; Tonon, C | 1 |
| Brandt, C; Klein, J; Löscher, W; Meller, S; Theilmann, W | 1 |
| Jiang, Y; Xiang, J | 1 |
| Dahlberg, D; Hassel, B; Ivanovic, J | 1 |
| Loureiro, AI; Sierra-Marcuño, G; Sierra-Paredes, G; Soares-da-Silva, P; Wright, LC | 1 |
| Chiu, NC; Ho, CS; Hsu, CH; Huang, JK; Lin, YJ; Tseng, HS | 1 |
| Berretta, N; Cecconi, F; Cervelli, M; Cervetto, C; D'Amelio, M; Marcoli, M; Mariottini, P; Maura, G; Mercuri, N; Passalacqua, M; Ragazzoni, M; Venturini, A; Vergani, L; Voci, A | 1 |
| Du, M; Li, J; Ma, J; Tang, J; Wang, R; Wu, Y | 1 |
| Akabani, G; Aramayo, R; Clanton, RM; Wu, G | 1 |
| Fadaie, F; Fesharaki, SS; Habibabadi, JM; Harirchian, MH; Kharazi, HH; Mobarakeh, NM; Rad, HS | 1 |
| Choudhary, AK; Lee, YY | 1 |
| Barker, GJ; Duncan, JS; McLean, MA; Salmenpera, TM; Simister, RJ | 1 |
| Iezhitsa, IN; Kharitonova, MV; Kravchenko, MS; Spasov, AA | 3 |
| Alfaro-Sáez, A; Bernabéu, A | 1 |
| Hetherington, HP; Pan, JW; Spencer, DD; Spencer, SS; Zaveri, HP | 1 |
| Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM | 1 |
| Becker, L; Carmona, MA; Feddersen, B; Filosa, A; Gaitanos, L; Honsek, SD; Klein, R; Klopstock, T; Kullander, K; Paixão, S; Pasquale, EB; Rose, CR; Rudhard, Y; Schoepfer, R | 1 |
| de Freitas, RM; de Oliveira Silva, F; Jordán, J; Saldanha, GB | 1 |
| González-Ramírez, M; González-Trujano, ME; Orozco-Suarez, S; Razo-Juárez, LI; Salgado-Ceballos, H; Sauer-Ramírez, JL | 1 |
| Balestrieri, A; Barberini, L; Bortolato, M; Genugu, F; Gioi, G; Marrosu, F; Puligheddu, M | 1 |
| Clarke, SG; Lowenson, JD; MacKay, KB | 1 |
| Dezortová, M; Hájek, M; Liscák, R; Vladyka, V; Vymazal, J | 1 |
| LABORIT, H; WEBER, B | 2 |
| WATSON, WJ; WOOD, JD | 2 |
| CRAWFORD, JM | 1 |
| MASSIEU, GH; ORTEGA, BG; PASANTES, H; TAPIA, R | 1 |
| CARACCIOLI, MD; CIMINO, F; CITTADINI, D; SALVATORE, F | 1 |
| ROA, PD; STONE, WE; TEWS, JK | 1 |
| CREMER, JE | 1 |
| Aniksztejn, L; Becq, H; Ben-Ari, Y; Demarque, M; Manent, JB; Represa, A; Villeneuve, N | 1 |
| Ball, WS; Care, M; Cecil, KM; Makoroff, KL | 1 |
| During, MJ; Klugmann, M; Leichtlein, CB; Serikawa, T; Symes, CW; Young, D | 1 |
| Bordessoules, M; Brissaud, O; Brun, M; Chateil, JF | 1 |
| Chang, KH; Chung, CK; Kim, DW; Kim, KK; Lee, SK; Song, IC | 1 |
| Doelken, M; Doerfler, A; Engelhorn, T; Ganslandt, O; Hammen, T; Kerling, F; Nimsky, C; Schwarz, M; Stadlbauer, A; Stefan, H | 1 |
| Abdelmalik, PA; Burnham, WM; Carlen, PL; Liang, P; Samoilova, M; Weisspapir, M | 1 |
| Baumgartner, C; Bittsanský, M; Gruber, S; Kaya, M; Lehner-Baumgartner, E; Mlynárik, V; Moser, E; Riederer, F; Serles, W | 1 |
| Narita, S | 1 |
| Massieu, GH; Ortega, BG; Pasantes, H; Pérez de la Mora, M; Tapia, R | 1 |
| Haug, P; Nitsch, C; Schmude, B | 1 |
| Donzanti, BA; Uretsky, NJ | 1 |
| Collins, JF; Croucher, MJ; Curry, K; Czuczwar, SJ; Joseph, M; Meldrum, BS; Stone, TW | 1 |
| Chapman, AG; Meldrum, BS; Premachandra, M; Westerberg, E | 1 |
| Croucher, MJ; Jones, AW; Meldrum, BS; Watkins, JC | 1 |
| Craig, CR | 1 |
| Halsey, MJ; Meldrum, BS; Wardley-Smith, B | 2 |
| Bruni, J; Hammond, EJ; Wilder, BJ | 1 |
| Czuczwar, SJ; Meldrum, B | 1 |
| Perkins, MN; Stone, TW | 1 |
| Chapman, AG; Meldrum, BS; Mendes, E | 1 |
| Honda, T | 1 |
| Casper, ES; Gralla, RJ; Kemeny, N; Wiley, RG | 1 |
| Amir, J; Merlob, P; Reisner, SH; Weitz, R | 1 |
| Abdul-Ghani, AS; Bradford, HF; Collins, JF; Coutinho-Netto, J | 1 |
| Casper, ES; Gralla, RJ; Natale, RB; Yagoda, A; Young, CW | 1 |
| Hashimoto, H; Hirabayashi, H; Hoshida, T; Kurokawa, S; Nakase, H; Ohnishi, H; Sakaki, T; Tada, T | 1 |
| Bradford, HF; Croucher, MJ; Hughes, PD; Kaura, S; Young, AM | 1 |
| Blumsom, NL; Gardiner, KA; Laming, PR | 1 |
| Mori, N | 1 |
| Flavin, HJ; Seyfried, TN | 1 |
| Biggs, CS; Fowler, LJ; Pearce, BR; Whitton, PS | 1 |
| Hönack, D; Hörstermann, D; Löscher, W; Rundfeldt, C; Wahnschaffe, U | 1 |
| Haapalinna, A; Halonen, T; Riekkinen, P; Valtonen, P | 1 |
| During, MJ; Gluckman, PD; Gunn, AJ; Gunning, MI; Mallard, CE; Tan, WK; Williams, CE | 1 |
| Aharon-Peretz, J; Chapman, J; Davidson, M; Friedman, E; Goldman, B; Korczyn, AD; Reznik-Wolf, H; St George Hyslop, PH; Treves, TA | 1 |
| Comair, YG; Hong, SC; Lüders, HO; Najm, IM; Ng, TC; Wang, Y | 1 |
| Ebinger, G; Michotte, Y; Smolders, I; Van Belle, K | 1 |
| Bruhn, T; Christensen, T; Diemer, NH | 1 |
| Ito, M; Kishi, K; Sejima, H; Shiraishi, H; Tsuda, H | 1 |
| Clarke, S; Kim, E; Lowenson, JD; MacLaren, DC; Young, SG | 1 |
| Dorandeu, F; Fosbraey, P; Lallement, G; Pernot-Marino, I; Tattersall, JE; Wetherell, J | 1 |
| Budziszewska, B; Jaworska-Feil, L; Lasoń, W; Leśkiewicz, M; Siwanowicz, J | 1 |
| Comair, YG; Lüders, HO; Najm, IM; Ng, TC; Shedid, D; Wang, Y | 1 |
| Aguilar-Veiga, E; Galán-Valiente, J; Mendez-Alvarez, E; Sierra-Marcuño, G; Sierra-Paredes, G; Soto-Otero, R; Vazquez-Illanes, MD | 1 |
| Attwell, PJ; Bradford, HF; Croucher, MJ; Jane, DE; Singh Kent, N | 1 |
| Andermann, F; Arnold, DL; Cendes, F; Dubeau, F; Li, LM; Miller, SP; Tasch, E | 1 |
| Ji, FY; Kaneko, K; Moriya, T; Obata, K; Shibata, S; Stork, O; Stork, S; Yoshinobu, Y | 1 |
| Akimitsu, T; Kitada, K; Kondo, A; Kuramoto, T; Maihara, T; Sasa, M; Serikawa, T; Shigematsu, Y; Yokoi, N | 1 |
| Aguilar-Veiga, E; Galán-Valiente, J; Sierra-Marcuño, G; Sierra-Paredes, G; Vazquez-Illanes, MD | 1 |
| Arikan, K; Coskun, T; Guvener, B; Oran, O | 1 |
| Bourne, JA; Fosbraey, P; Halliday, J | 1 |
| Hada, J; Hayashi, Y; Jiang, MH; Kaku, T; Morimoto, K | 1 |
| el-Yamany, NA; Horn, E | 1 |
| Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ | 1 |
| Collins, RC; Mehta, S | 1 |
| Grove, J; Schechter, PJ; Tranier, Y | 1 |
| Battistin, L | 1 |
| Battistin, L; Lorenzi, AD; Varotto, M | 1 |
| Aquila, WJ; During, MJ; Ley, E; Tendler, D; Young, RS | 1 |
| Bixler, MA; Coyle, JT; Koller, KJ; Meyerhoff, JL; Robinson, MB | 1 |
| Berg, M; Bruhn, T; Cobo, M; Diemer, NH | 1 |
| Carlson, H; Hillered, L; Ronne-Engström, E; Ungerstedt, U | 1 |
| Eguchi, T; Hirabayashi, H; Morimoto, T; Nakase, H; Sakaki, T; Tada, T | 2 |
| Oles, RJ; Singh, L; Tricklebank, MD | 1 |
| Ciesielski, L; Clement, J; Mandel, P; Simler, S | 1 |
| Higashihara, Y; Hiramatsu, M; Mori, A | 1 |
| Brancati, A; D'Arcangelo, P | 1 |
| Donald, AE; Foster, AC; Hutson, PH; Iversen, LL; Iversen, SD; Kemp, JA; Leeson, PD; Marshall, GR; Oles, RJ; Singh, L | 1 |
| Colpaert, FC; Koek, W | 1 |
| Kesingland, AC; Singh, L; Tricklebank, MD; Wong, EH | 1 |
| Oles, R; Singh, L; Woodruff, G | 1 |
| Johnston, MV; McDonald, JW; Silverstein, FS | 2 |
| Cruz, LJ; Haack, JA; Mena, EE; Olivera, BM; Parks, TN; Rivier, J | 1 |
| Gennings, C; Kapetanovic, IM; Kupferberg, HJ; Torchin, CD | 1 |
| Kulkarni, SK; Mehta, AK; Ticku, MK | 1 |
| Dolin, SJ; Halsey, MJ; Hunter, AB; Little, HJ | 1 |
| Ahier, RG; Middlemiss, DN; Price, GW; Singh, L; Tricklebank, MD; Wong, EH | 1 |
| Borosky, S; Ellenberger, SR; Ferkany, JW; Guzewska, ME; Jones, SM; Kyle, DJ; Rzeszotarski, WJ; Sacaan, AI; Snell, LD; Willets, J | 1 |
| Iversen, SD; Oles, RJ; Preston, C; Singh, L; Tricklebank, MD | 1 |
| Curran, T; Hempstead, J; Macgregor-Leon, PF; Mitchelmore, C; Morgan, JI; Sonnenberg, JL | 1 |
| Halsey, MJ; Meldrum, BS; Millan, MH; Wardley-Smith, B | 1 |
| Bergmann, F; Feigenbaum, JJ; Kloog, Y; Mechoulam, R; Nadler, V; Richmond, SA; Sokolovsky, M | 1 |
| Drejer, J; Honoré, T; Jensen, LH; Sheardown, MJ; Stidsen, CE | 1 |
| Pierson, MG; Smith, KL; Swann, JW | 1 |
| Anderson, WW; Clark, S; Stasheff, SF; Wilson, WA | 1 |
| Moreau, JL; Pieri, L; Prud'hon, B | 1 |
| Turski, WA | 1 |
| Jacobson, AE; Mattson, MV; Rice, KC; Rogawski, MA; Thurkauf, A; Yamaguchi, S | 1 |
| Chapman, AG; Meldrum, BS | 1 |
| McCaslin, PP; Morgan, WW | 1 |
| Amrick, CL; Bennett, DA; Bernard, PS | 1 |
| Burton, NR; Stone, TW | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Wamil, A | 1 |
| Klockgether, T; Lehmann, J; Schwarz, M; Sontag, KH; Turski, L | 1 |
| Chapman, AG; Hutchison, A; Lehmann, J; Meldrum, BS; Tsai, C; Wood, PL | 1 |
| Meldrum, BS; Millan, MH; Patel, S | 1 |
| Collins, JF; Meldrum, BS; Turski, L | 1 |
| Chapman, AG; Cheetham, SC; Hart, GP; Meldrum, BS; Westerberg, E | 1 |
| Meldrum, B; Schwarcz, R | 1 |
| Goldberg, O; Teichberg, VI | 1 |
| Aleksandrov, VG; Lapin, IP; Mandel'shtam, IuE; Ryzhov, IV; Slepokurov, MV | 1 |
| Frenk, H; Liban, A; Teichberg, VI; Urca, G | 1 |
| Gale, K; Piredda, S | 1 |
| Sloviter, RS | 1 |
| Suzuki, S; Yamazaki, M | 1 |
| Bennett, DA; Bernard, P; Boehm, C; Lehmann, J; McPherson, S; Murphy, DE; Pastor, G; Schneider, J; Steel, DJ; Tsai, C | 1 |
| Breese, GR; Givens, BS; McCown, TJ | 1 |
| Choi, DW; Coulter, DA; Prince, DA; Wong, BY | 1 |
| Hutchison, AJ; Lehmann, J; McPherson, SE; Mondadori, C; Murphy, DE; Schmutz, M; Sinton, CM; Steel, DJ; Tsai, C; Williams, M | 1 |
| Chapman, AG; Hart, GP | 1 |
| Beitz, AJ; Larson, AA | 1 |
| Cavalheiro, EA; Turski, L | 1 |
| Cavalheiro, EA; Meldrum, BS; Turski, L; Turski, WA | 1 |
| Borosky, SA; Clissold, DB; Ferkany, JW; Pontecorvo, MJ | 1 |
| De Sarro, GB; Meldrum, BS; Patel, S | 1 |
| French, ED; Schwarcz, R; Ungerstedt, U; Vezzani, A | 1 |
| Chapman, AG; Engelsen, B; Meldrum, BS | 1 |
| Faingold, CL; Meldrum, BS; Millan, MH | 1 |
| Bonhaus, DW; McNamara, JO; Silver, JM | 1 |
| Balm, M; Coyle, JT; Markl, A; Zaczek, R | 1 |
| Klockgether, T; Meldrum, BS; Schwarz, M; Sontag, KH; Turski, L | 1 |
| Czuczwar, SJ; Frey, HH; Löscher, W | 1 |
| Chapman, AG; Hart, GP; Meldrum, BS; Turski, L; Watkins, JC | 1 |
| Bergenstal, R; Burg, A; Cooney, DA; Fleischman, R; Morrison, R; Yavelow, J; Zlotoff, R | 1 |
| Sacktor, B; Tiekert, CG; Wilson, JE | 1 |
| Okudera, N | 1 |
| Nordmann, J; Nordmann, R; Petit, MA | 1 |
| Brown, DJ; Stone, WE | 1 |
| Gallagher, BB; Reynolds, AP | 1 |
| Carl, JL; King, LJ; Lao, L | 1 |
| Brown, DJ; Stone, WE; Tews, JK; Whisler, KE | 1 |
| Knaape, HH; Wiechert, P | 1 |
| Dobkin, J | 1 |
| Koeppe, RE; Mushahwar, IK | 1 |
| Elliott, KA; Yoshino, Y | 3 |
| Hata, T; Kita, T; Murakami, T | 1 |
| Okudzhava, VM; Saradzhishvili, PM; Vetgoron, FG | 1 |
| Brancati, A; D'Arcangelo, P; Lino, A; Pacchieri, V | 1 |
| Koenig, H; Patel, A | 1 |
| Gómez, CJ; Pasquini, JM; Salomone, JR | 1 |
| Baumgartner, R; Hottinger, A; Scheidegger, S; Stalder, G | 1 |
| Göllnitz, G; Wiechert, P | 3 |
| Minard, FN; Richter, D | 1 |
| Cheema, PS; Malathi, K; Padmanaban, G; Sarma, PS | 1 |
| Macaione, S; Palma, MM; Pandolfo, I | 1 |
| Fleming, MC; Lowry, OH | 1 |
| Balestrieri, C; Cimino, F; Cittadini, D; De Cristofaro, D | 1 |
7 review(s) available for aspartic acid and Absence Seizure
| Article | Year |
|---|---|
Control of seizures by ketogenic diet-induced modulation of metabolic pathways.
Topics: Amino Acids, Essential; Aspartic Acid; Demyelinating Diseases; Diet, Ketogenic; Epilepsy; Fatty Acids, Volatile; Humans; Ketone Bodies; Malates; Metabolic Networks and Pathways; Mitochondria; Monocarboxylic Acid Transporters; Seizures | 2017 |
Neurophysiological symptoms and aspartame: What is the connection?
Topics: Affect; Animals; Aspartame; Aspartic Acid; Brain; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Free Radicals; Humans; Hydrocortisone; Migraine Disorders; Nervous System Diseases; Neurotransmitter Agents; Non-Nutritive Sweeteners; Norepinephrine; Oxidative Stress; Phenylalanine; Seizures; Serotonin; Sleep Initiation and Maintenance Disorders | 2018 |
Central actions of valproic acid in man and in experimental models of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Action Potentials; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Aspartic Acid; Brain; Cyclic GMP; Dyskinesia, Drug-Induced; Electric Stimulation; Electrophysiology; Epilepsies, Partial; gamma-Aminobutyric Acid; Glycine; Humans; Nervous System Diseases; Neurons; Seizures; Serotonin; Succinate-Semialdehyde Dehydrogenase; Succinates; Valproic Acid | 1981 |
Roles of excitatory amino acids in expression of secondarily generalized limbic seizures: observations in the kindling model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dimethyl Sulfoxide; Electric Stimulation; Glutamates; Glutamic Acid; Humans; Kindling, Neurologic; Seizures | 1993 |
NMDA receptors and ligands in the vertebrate CNS.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Behavior, Animal; Binding, Competitive; Central Nervous System; Evoked Potentials; Kinetics; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Anticonvulsant drug action and regional neurotransmitter amino acid changes.
Topics: Acetamides; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Neurotransmitter Agents; Seizures | 1988 |
More meditations of MSG.
Topics: Age Factors; Amino Acids; Animals; Aspartic Acid; Brain; Chickens; Food Additives; Glutamates; Glutamine; Haplorhini; Humans; Liver; Macaca; Potassium; Rats; Seizures; Sodium | 1973 |
1 trial(s) available for aspartic acid and Absence Seizure
| Article | Year |
|---|---|
Medial temporal lobe neuronal damage in temporal and extratemporal lesional epilepsy.
Topics: Action Potentials; Adolescent; Adult; Analysis of Variance; Aspartic Acid; Brain Neoplasms; Child; Creatine; Electroencephalography; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Ganglioglioma; Hippocampus; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Neurons; Oligodendroglioma; Seizures; Temporal Lobe | 2000 |
188 other study(ies) available for aspartic acid and Absence Seizure
| Article | Year |
|---|---|
1H-MRS reveals metabolic alterations in generalized tonic-clonic seizures before and after treatment.
Topics: Aspartic Acid; Creatine; Dorsolateral Prefrontal Cortex; Humans; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy; Seizures | 2022 |
Progressive tremor and motor impairment in seizure-prone mutant tremor mice are associated with neurotransmitter dysfunction.
Topics: Animals; Aspartic Acid; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Mice; Motor Disorders; Neurotransmitter Agents; Norepinephrine; Seizures; Serotonin; Tremor | 2023 |
Hypomagnesemia with Secondary Hypocalcemia (HSH): a Case Report.
Topics: Aspartic Acid; Calcitriol; Calcium; Calcium Carbonate; Child; Cholecalciferol; Humans; Hypocalcemia; Magnesium; Male; Potassium Chloride; Seizures; Tablets | 2023 |
2-D magnetic resonance spectroscopic imaging of the pediatric brain using compressed sensing.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Cohort Studies; Databases, Factual; Female; Humans; Image Interpretation, Computer-Assisted; Infant; Infant, Newborn; Magnetic Resonance Spectroscopy; Male; Radiation Exposure; Retrospective Studies; Risk Assessment; Seizures; Sensitivity and Specificity; Sex Factors; Time Factors | 2019 |
Neurochemicals of limbic system and thalamofrontal cortical network: Are they different between patients with idiopathic generalized epilepsy and psychogenic nonepileptic seizure?
Topics: Adult; Aspartic Acid; Choline; Creatine; Epilepsy, Generalized; Humans; Magnetic Resonance Spectroscopy; Seizures | 2020 |
Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytes; Brain Neoplasms; Female; Glioma; Glutamic Acid; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Multivariate Analysis; Mutation; Oligodendroglia; Seizures; Survival Analysis; Young Adult | 2021 |
Magnetic Resonance Spectroscopy Findings in Patients with Dural Arteriovenous Fistulas: Three Case Reports.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Central Nervous System Vascular Malformations; Cerebral Angiography; Creatine; Headache; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurosurgical Procedures; Seizures; Transverse Sinuses | 2017 |
Proton MR Spectroscopy in Patients With Sleep-Related Hypermotor Epilepsy (SHE): Evidence of Altered Cingulate Cortex Metabolism.
Topics: Adult; Aspartic Acid; Case-Control Studies; Creatine; Epilepsy; Female; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Seizures; Sleep; Thalamus | 2017 |
Commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and subsequent epileptogenesis in two rat models of temporal lobe epilepsy.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Female; Glutamic Acid; Hippocampus; Lysine; Microdialysis; Neurotransmitter Agents; Pilocarpine; Rats; Scopolamine; Seizures; Status Epilepticus; Temporal Lobe | 2019 |
Antiepileptic potential of matrine via regulation the levels of gamma-aminobutyric acid and glutamic acid in the brain.
Topics: Alkaloids; Animals; Anticonvulsants; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Glycine; Male; Matrines; Mice; Mice, Inbred ICR; Motor Activity; Pentylenetetrazole; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Seizures; Up-Regulation | 2013 |
High extracellular concentration of excitatory amino acids glutamate and aspartate in human brain abscess.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Abscess; Child; Child, Preschool; Extracellular Space; Female; Glutamic Acid; Humans; Male; Middle Aged; Seizures; Young Adult | 2014 |
Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus.
Topics: Acute Disease; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Chronic Disease; Dibenzazepines; Disease Models, Animal; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Seizures; Taurine; Thiazolidines | 2014 |
The Reversible Corpus Callosum Splenium Lesion in A Neonate with Hypoglycemia and Seizure.
Topics: Aspartic Acid; Corpus Callosum; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Seizures | 2015 |
Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse.
Topics: Animals; Aspartic Acid; Astrocytes; Benzodiazepines; Biogenic Polyamines; Calcium; Cerebral Cortex; Enzyme Induction; Genetic Predisposition to Disease; Gliosis; Hippocampus; Kainic Acid; Male; Metallothionein; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Neurotoxins; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Receptors, AMPA; Recombinant Fusion Proteins; Seizures; Synaptosomes; Up-Regulation | 2016 |
Dynamic transition of neuronal firing induced by abnormal astrocytic glutamate oscillation.
Topics: Aspartic Acid; Astrocytes; Glutamic Acid; Hippocampus; Humans; Neuroglia; Neurons; Receptors, N-Methyl-D-Aspartate; Seizures; Synapses | 2016 |
1H-MRS metabolite's ratios show temporal alternation in temporal lobe seizure: Comparison between interictal and postictal phases.
Topics: Adult; Aspartic Acid; Choline; Creatinine; Drug Resistant Epilepsy; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Magnetic Resonance Imaging; Male; Proton Magnetic Resonance Spectroscopy; Seizures; Temporal Lobe; Time Factors; Video Recording; Young Adult | 2016 |
The effect of epileptic seizures on proton MRS visible neurochemical concentrations.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Data Interpretation, Statistical; Dipeptides; Female; Glutamic Acid; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Protons; Seizures | 2008 |
[The characterization of central neuromediation in rats fed with magnesium-deprived diet before and after magnesium replenishment].
Topics: Animals; Aspartic Acid; Cations, Divalent; Diet; Magnesium; Magnesium Chloride; Magnesium Deficiency; Male; Motor Activity; Neurotransmitter Agents; Rats; Reaction Time; Seizures; Stereotyped Behavior; Vitamin B 6; Vitamins | 2008 |
[In vivo magnetic resonance spectroscopy in the measurement of mesial temporal sclerosis].
Topics: Aspartic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Sclerosis; Seizures; Sensitivity and Specificity; Temporal Lobe; Young Adult | 2009 |
Features of central neurotransmission in animals in conditions of dietary magnesium deficiency and after its correction.
Topics: Animals; Aspartic Acid; Cations, Divalent; Diet; Magnesium; Magnesium Chloride; Magnesium Deficiency; Male; Motor Activity; Neurotransmitter Agents; Rats; Reaction Time; Seizures; Stereotyped Behavior; Vitamin B 6; Vitamins | 2009 |
Intracranial EEG power and metabolism in human epilepsy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Creatine; Electrodes, Implanted; Electroencephalography; Energy Metabolism; Epilepsy; Female; Fourier Analysis; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Seizures | 2009 |
In vivo glutamate decline associated with kainic acid-induced status epilepticus.
Topics: Analysis of Variance; Animals; Aspartic Acid; Disease Progression; Glutamic Acid; Hippocampus; Image Processing, Computer-Assisted; Immunohistochemistry; Kainic Acid; Lactic Acid; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurons; Organ Size; Rats; Rats, Wistar; Seizures; Status Epilepticus; Time Factors | 2009 |
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport.
Topics: Animals; Animals, Newborn; Aspartic Acid; Biophysics; Disease Models, Animal; Electric Stimulation; Ephrin-A3; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroglia; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Pentylenetetrazole; Receptor, EphA4; Seizures; Signal Transduction; Synapses; Up-Regulation | 2009 |
Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dialysis; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Survival Analysis; Thioctic Acid | 2011 |
Anticonvulsive effect of vitamin C on pentylenetetrazol-induced seizures in immature rats.
Topics: Animals; Anticonvulsants; Ascorbic Acid; Aspartic Acid; Brain Chemistry; Chromatography, High Pressure Liquid; Convulsants; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; gamma-Aminobutyric Acid; Glutamates; Glutamine; Male; Pentylenetetrazole; Progesterone; Rats; Rats, Sprague-Dawley; Seizures; Vitamins | 2010 |
Dissociation between neurovegetative signs and subjective symptoms in a case of idiopathic pilomotor seizures.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Electroencephalography; Epilepsy, Complex Partial; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Piloerection; Seizures; Tachycardia | 2010 |
Wortmannin reduces insulin signaling and death in seizure-prone Pcmt1-/- mice.
Topics: Administration, Oral; Androstadienes; Animals; Asparagine; Aspartic Acid; Brain; Female; Insulin; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Organ Size; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Processing, Post-Translational; Seizures; Signal Transduction; Wortmannin | 2012 |
1H MR spectroscopy of mesial temporal lobe epilepsies treated with Gamma knife.
Topics: Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Epilepsy, Temporal Lobe; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lipid Metabolism; Lipids; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Postoperative Complications; Radiation Injuries; Radiation Tolerance; Radiosurgery; Seizures; Time Factors; Treatment Failure | 2003 |
[Protection of rats against isoniazid-induced convulsions by the potassium and magnesium salts of DL-aspartic acid].
Topics: Animals; Aspartic Acid; Isoniazid; Magnesium; Potassium; Rats; Salts; Seizures | 1959 |
GAMMA-AMINOBUTYRIC ACID LEVELS IN THE BRAIN OF RATS EXPOSED TO OXYGEN AT HIGH PRESSURES.
Topics: Aminobutyrates; Aspartic Acid; Atmospheric Pressure; Brain; gamma-Aminobutyric Acid; Glutamates; Metabolism; Oxygen; Pressure; Rats; Research; Seizures | 1963 |
THE EFFECT UPON MICE OF INTRAVENTRICULAR INJECTION OF EXCITANT AND DEPRESSANT AMINO ACIDS.
Topics: Amino Acids; Aminobutyrates; Aspartic Acid; Cerebral Ventricles; Glutamates; Hypnotics and Sedatives; Injections; Injections, Intraventricular; Mice; Pharmacology; Research; Seizures; Sulfonic Acids; Taurine; Toxicology | 1963 |
CONVULSANT EFFECT OF L-GLUTAMIC ACID-GAMMA-HYDRAZIDE BY SIMULTANEOUS TREATMENT WITH PYRIDOXAL PHOSPHATE.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain; Carboxy-Lyases; Convulsants; Glutamates; Glutamine; Hydrazines; Mice; Pharmacology; Proteins; Pyridoxal Phosphate; Research; Seizures; Toxicology | 1964 |
ON THE MECHANISM OF AMMONIA DETOXICATION BY L-ORNITHINE AND L-ASPARTATE.
Topics: Ammonia; Aspartic Acid; Blood Chemical Analysis; Enzyme Inhibitors; Ligases; Liver; Ornithine; Pharmacology; Rats; Research; Seizures; Toxicology; Urea | 1964 |
A NEUROCHEMICAL STUDY OF THIOSEMICARBAZIDE SEIZURES AND THEIR INHIBITION BY AMINO-OXYACETIC ACID.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Azides; Brain; Dogs; Electrophysiology; Glutamine; Lactates; Lysine; Nerve Tissue Proteins; Neurochemistry; Pentylenetetrazole; Pharmacology; Research; Seizures; Semicarbazides; Thiosemicarbazones; Toxicology; Tyrosine | 1964 |
AMINO ACID METABOLISM IN RAT BRAIN STUDIED WITH 14C-LABELLED GLUCOSE.
Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamates; Glutamine; Glycine; Lead; Nitrophenols; Proteins; Rats; Research; Seizures; Serine; Threonine; Tin; Toxicology | 1964 |
MOLECULAR STRUCTURE-ACTIVITY RELATIONSHIPS OF COMPOUNDS PROTECTING RATS AGAINST OXYGEN POISONING.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Antidotes; Arginine; Aspartic Acid; Blood-Brain Barrier; Dipeptides; Ethylamines; Glucose; Glutamates; Hyperbaric Oxygenation; Lysine; Oxygen; Pharmacology; Poisoning; Protective Agents; Rats; Research; Seizures; Sodium Chloride; Structure-Activity Relationship; Toxicology; Urea | 1964 |
[Protective effect of potassium and magnesium salts of DL-aspartic acid against convulsions caused by isoniazid and ammonium chloride in the rat].
Topics: Ammonium Chloride; Animals; Aspartic Acid; Isoniazid; Magnesium; Potassium; Rats; Salts; Seizures | 1959 |
Glutamate transporters prevent the generation of seizures in the developing rat neocortex.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Biological Clocks; Calcium Signaling; Excitatory Amino Acid Agonists; Glutamic Acid; N-Methylaspartate; Neocortex; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 2004 |
Elevated lactate as an early marker of brain injury in inflicted traumatic brain injury.
Topics: Aspartic Acid; Brain Chemistry; Brain Injuries; Critical Care; Female; Fractures, Bone; Frontal Lobe; Glasgow Outcome Scale; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn; Lactic Acid; Length of Stay; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurologic Examination; Occipital Lobe; Parietal Lobe; Prospective Studies; Retinal Hemorrhage; Seizures | 2005 |
Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease.
Topics: Amidohydrolases; Animals; Aspartic Acid; Canavan Disease; Central Nervous System; Dependovirus; Disease Models, Animal; Female; Gene Expression; Male; Motor Neurons; Myelin Sheath; Rats; Seizures | 2005 |
Chemical shift imaging and localised magnetic resonance spectroscopy in full-term asphyxiated neonates.
Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Brain; Choline; Creatine; Electroencephalography; Female; Humans; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; Male; Prospective Studies; Seizures | 2005 |
Effect of seizure on hippocampus in mesial temporal lobe epilepsy and neocortical epilepsy: an MRS study.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Epilepsy, Temporal Lobe; Female; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Neocortex; Protons; Radionuclide Imaging; Seizures | 2005 |
1H-MR spectroscopy indicates severity markers in temporal lobe epilepsy: correlations between metabolic alterations, seizures, and epileptic discharges in EEG.
Topics: Adult; Aspartic Acid; Biomarkers; Brain Mapping; Choline; Creatine; Dipeptides; Electroencephalography; Epilepsy, Temporal Lobe; Female; Functional Laterality; Glutamine; Hippocampus; Humans; Magnetic Resonance Spectroscopy; Male; Monitoring, Physiologic; Seizures; Severity of Illness Index; Temporal Lobe; Videotape Recording | 2007 |
Factors which abolish hypoglycemic seizures do not increase cerebral glycogen content in vitro.
Topics: Age Factors; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Aspartic Acid; Cerebellum; Disease Models, Animal; Drug Combinations; Excitatory Amino Acid Antagonists; Glucose; Glycogen; Hippocampus; Hypoglycemia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Seizures; Synaptic Transmission; Tetrodotoxin | 2008 |
Decrease of NAA with aging outside the seizure focus in mesial temporal lobe epilepsy--a proton-MRS study at 3 Tesla.
Topics: Adolescent; Adult; Aging; Aspartic Acid; Choline; Creatine; Drug Resistance; Epilepsy, Temporal Lobe; Female; Functional Laterality; Humans; Magnetic Resonance Spectroscopy; Male; Memory; Neuropsychological Tests; Protons; Seizures; Temporal Lobe; Verbal Learning | 2007 |
Effect of magnesium chloride and magnesium L-aspartate on seizure threshold in rats under conditions of dietary magnesium deficiency.
Topics: Animals; Anticonvulsants; Aspartic Acid; Magnesium Chloride; Magnesium Deficiency; Male; Pentylenetetrazole; Pyridoxine; Rats; Seizures | 2007 |
[Behavioral and electrographic changes during hippocampal--seizure induced by N-mechyl aspartic acid in cats].
Topics: Animals; Aspartic Acid; Behavior, Animal; Cats; Electroencephalography; Hippocampus; Seizures | 1966 |
Free amino acids and glutamate decarboxylase activity in brain of mice during drug-induced convulsions.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Carboxy-Lyases; Glutamates; Glutamine; Hydrazines; Insulin; Methionine; Methionine Sulfoximine; Mice; Pentylenetetrazole; Pyridoxal Phosphate; Seizures; Thiosemicarbazones; Transaminases | 1967 |
Alterations in the content of amino acid neurotransmitters before the onset and during the course of methoxypyridoxine-induced seizures in individual rabbit brain regions.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Neurotransmitter Agents; Pyridoxine; Rabbits; Seizures; Taurine; Tissue Distribution | 1983 |
Effects of excitatory amino acids on locomotor activity after bilateral microinjection into the rat nucleus accumbens: possible dependence on dopaminergic mechanisms.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Septal Nuclei; Synaptic Transmission | 1983 |
A comparison of the anticonvulsant potency of (+/-) 2-amino-5-phosphonopentanoic acid and (+/-) 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Valine | 1983 |
Changes in regional neurotransmitter amino acid levels in rat brain during seizures induced by L-allylglycine, bicuculline, and kainic acid.
Topics: Allylglycine; Amino Acids; Animals; Aspartic Acid; Bicuculline; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Male; Neurotransmitter Agents; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Taurine | 1984 |
Suppression of audiogenic seizures in DBA/2 mice by two new dipeptide NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Glutamates; Glutamine; Mice; Mice, Inbred DBA; Seizures; Valine | 1984 |
Evidence for a role of neurotransmitters in the mechanism of topical convulsant models.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Aspartic Acid; Brain; Choline O-Acetyltransferase; Disease Models, Animal; Dopamine; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Neurotransmitter Agents; Norepinephrine; Rats; Seizures; Taurine | 1984 |
The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Fasting; Glutamates; Glutamic Acid; Male; Myoclonus; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission; Syndrome; Tremor | 1984 |
Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Seizures | 1982 |
On the interaction of 2-amino-7-phosphono-heptanoic acid and quinolinic acid in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Iontophoresis; Male; Mice; N-Methylaspartate; Neurons; Pyridines; Quinolinic Acids; Seizures | 1983 |
Acute anticonvulsant activity of structural analogues of valproic acid and changes in brain GABA and aspartate content.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Aspartic Acid; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Mice; Mice, Inbred DBA; Seizures; Structure-Activity Relationship; Valproic Acid | 1983 |
Amino acid metabolism in the brain with convulsive disorders. Part I: Free amino acid patterns in the brain of E1 mouse with convulsive seizure.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Cystathionine; gamma-Aminobutyric Acid; Glutamine; Mice; Mice, Inbred Strains; Ornithine; Seizures; Serine | 1984 |
Neurotoxicity of the pyrimidine synthesis inhibitor N-phosphonoacetyl-L-aspartate.
Topics: Adult; Aged; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Brain Diseases; Disease Models, Animal; Epilepsy; Female; Humans; Male; Middle Aged; Organophosphorus Compounds; Phosphonoacetic Acid; Rats; Rats, Inbred Strains; Seizures; Uridine | 1982 |
A possible role for aspartic acid in neonatal seizures.
Topics: Animals; Aspartic Acid; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mice; Rats; Seizures | 1981 |
Is glutamate a trigger factor in epileptic hyperactivity?
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Female; Glutamates; Organophosphorus Compounds; Rats; Seizures | 1981 |
Phase I trial of PALA.
Topics: Antineoplastic Agents; Aspartic Acid; Brain Diseases; Diarrhea; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Humans; Leukocyte Count; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Platelet Count; Seizures; Skin Diseases | 1980 |
Experimental study of the mechanism of seizure induction: changes in the concentrations of excitatory amino acids in the epileptic focus of the cat amygdaloid kindling model.
Topics: Amygdala; Animals; Aspartic Acid; Cats; Excitatory Amino Acids; Glutamic Acid; Seizures | 1994 |
Effect of amygdaloid kindling on the content and release of amino acids from the amygdaloid complex: in vivo and in vitro studies.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Cerebral Cortex; Dialysis; Electric Stimulation; Glutamic Acid; Glutamine; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Seizures | 1995 |
Brain amino acid levels are related to seizure propensity in the gerbil (Meriones unguiculatus).
Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Aspartic Acid; Behavior, Animal; Brain; Citrulline; Cysteine; Disease Susceptibility; Female; Gerbillinae; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Male; Seizures | 1993 |
Enhanced aspartate release related to epilepsy in (EL) mice.
Topics: Aging; Animals; Aspartic Acid; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Potassium; Seizures; Species Specificity | 1994 |
Effect of isonicotinic acid hydrazide on extracellular amino acids and convulsions in the rat: reversal of neurochemical and behavioural deficits by sodium valproate.
Topics: Amino Acids; Animals; Aspartic Acid; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Isoniazid; Kinetics; Male; Potassium; Rats; Rats, Wistar; Seizures; Taurine; Valproic Acid | 1994 |
Transmitter amino acid levels in rat brain regions after amygdala-kindling or chronic electrode implantation without kindling: evidence for a pro-kindling effect of prolonged electrode implantation.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Brain; Chromatography, High Pressure Liquid; Electric Stimulation; Electrodes; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kindling, Neurologic; Neurotransmitter Agents; Prostheses and Implants; Rats; Rats, Wistar; Seizures; Taurine | 1993 |
Effect of alpha 2-adrenergic drugs dexmedetomidine and atipamezole on extracellular amino acid levels in vivo.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amino Acids; Animals; Aspartic Acid; Calcium; Epilepsy; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Imidazoles; Male; Medetomidine; Microdialysis; Potassium; Rats; Rats, Wistar; Seizures; Spectrometry, Fluorescence | 1995 |
Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ischemic injury in late gestation fetal sheep.
Topics: Animals; Aspartic Acid; Brain Edema; Brain Ischemia; Cytotoxins; Electroencephalography; Extracellular Space; Female; Fetal Hypoxia; gamma-Aminobutyric Acid; Gestational Age; Glutamic Acid; Hypoxia, Brain; Nitric Oxide; Pregnancy; Reperfusion Injury; Seizures; Sheep; Time Factors | 1996 |
A novel mutation of presenilin 1 in familial Alzheimer's disease in Israel detected by denaturing gradient gel electrophoresis.
Topics: Alzheimer Disease; Aspartic Acid; Electrophoresis, Polyacrylamide Gel; Exons; Female; Glutamic Acid; Humans; Male; Membrane Proteins; Middle Aged; Pedigree; Presenilin-1; Seizures | 1996 |
Temporal changes in proton MRS metabolites after kainic acid-induced seizures in rat brain.
Topics: Animals; Aspartic Acid; Brain; Cell Count; Choline; Creatinine; Dipeptides; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neuropeptides; Protons; Rats; Rats, Sprague-Dawley; Seizures; Temporal Lobe | 1997 |
Hippocampal and cerebellar extracellular amino acids during pilocarpine-induced seizures in freely moving rats.
Topics: Amino Acids; Animals; Aspartic Acid; Carbamazepine; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures | 1997 |
Evidence for increased cellular uptake of glutamate and aspartate in the rat hippocampus during kainic acid seizures. A microdialysis study using the "indicator diffusion' method.
Topics: Animals; Aspartic Acid; Disease Models, Animal; Glutamic Acid; Hippocampus; Kainic Acid; Male; Microdialysis; Rats; Rats, Wistar; Seizures | 1997 |
Regional excitatory and inhibitory amino acid concentrations in pentylenetetrazol kindling and kindled rat brain.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Convulsants; gamma-Aminobutyric Acid; Glutamic Acid; Kindling, Neurologic; Male; Neural Inhibition; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Taurine | 1997 |
Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.
Topics: Animals; Asparagine; Aspartic Acid; Body Weight; Death, Sudden; DNA Primers; Female; Growth Disorders; Heterozygote; Humans; Infant, Newborn; Male; Mice; Mice, Knockout; Pentylenetetrazole; Polymerase Chain Reaction; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Methyltransferases; Proteins; Recombinant Proteins; Restriction Mapping; Seizures | 1997 |
Effects of excitatory amino acid antagonists on dendrotoxin-induced increases in neurotransmitter release and epileptiform bursting in rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Aspartic Acid; Dizocilpine Maleate; Elapid Venoms; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Neurotoxins; Neurotransmitter Agents; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures | 1997 |
Protective effects of neurosteroids against NMDA-induced seizures and lethality in mice.
Topics: Animals; Anticonvulsants; Aspartic Acid; Hippocampus; In Vitro Techniques; Lethal Dose 50; Male; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Seizures; Steroids | 1998 |
MRS metabolic markers of seizures and seizure-induced neuronal damage.
Topics: Animals; Aspartic Acid; Biomarkers; Brain; Cell Count; Choline; Creatine; Cycloheximide; Hippocampus; Kainic Acid; Lactates; Magnetic Resonance Spectroscopy; Male; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 1998 |
Extracellular amino acids in the rat hippocampus during picrotoxin threshold seizures in chronic microdialysis experiments.
Topics: Amino Acids; Animals; Aspartic Acid; Electroencephalography; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Microdialysis; Picrotoxin; Rats; Rats, Sprague-Dawley; Seizures; Taurine | 1998 |
Anticonvulsant and glutamate release-inhibiting properties of the highly potent metabotropic glutamate receptor agonist (2S,2'R, 3'R)-2-(2',3'-dicarboxycyclopropyl)glycine (DCG-IV).
Topics: Amygdala; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Cyclopropanes; Glutamic Acid; Glycine; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Synaptosomes; Triazines | 1998 |
Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65.
Topics: Age Factors; Aggression; Animals; Anxiety; Aspartic Acid; Brain; Brain Chemistry; Circadian Rhythm; Electroencephalography; Emotions; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Isoenzymes; Male; Mice; Mice, Knockout; Neurons; Neurotransmitter Agents; Seizures; Survival Rate | 2000 |
Accumulation of N-acetyl-L-aspartate in the brain of the tremor rat, a mutant exhibiting absence-like seizure and spongiform degeneration in the central nervous system.
Topics: Amidohydrolases; Animals; Aspartic Acid; Base Sequence; Blotting, Southern; Central Nervous System; Chromosome Mapping; Cloning, Molecular; Electroencephalography; Epilepsy, Absence; Gene Deletion; Genome; Injections, Intraventricular; Male; Mice; Molecular Sequence Data; Nerve Degeneration; Rats; Rats, Mutant Strains; Rats, Wistar; Seizures; Tremor | 2000 |
Effect of ionotropic glutamate receptors antagonists on the modifications in extracellular glutamate and aspartate levels during picrotoxin seizures: a microdialysis study in freely moving rats.
Topics: Animals; Anti-Anxiety Agents; Aspartic Acid; Benzodiazepines; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Seizures | 2000 |
Effects of ammonia on pentylenetetrazole-induced seizure threshold.
Topics: Ammonia; Animals; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Hepatic Encephalopathy; Linear Models; Male; Neurons; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1999 |
Changes in striatal electroencephalography and neurochemistry induced by kainic acid seizures are modified by dopamine receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Electroencephalography; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Homovanillic Acid; Kainic Acid; Neurochemistry; Receptors, Dopamine D1; Receptors, Dopamine D2; Seizures; Sulpiride | 2001 |
Sodium nitroprusside-induced seizures and adenosine release in rat hippocampus.
Topics: Adenosine; Animals; Aspartic Acid; Chelating Agents; Dithiothreitol; Ditiocarb; Hippocampus; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Wistar; Seizures; Vasodilator Agents | 2001 |
Time courses of aspartate and glutamate concentrations in the focus area during penicillin induced epileptiform activity in awake rats.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; Glutamic Acid; Male; Microdialysis; Penicillins; Rats; Rats, Wistar; Seizures; Time Factors | 2002 |
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pregnancy; Pregnancy Complications; Seizures; Syndrome; Tissue Distribution; Vision Disorders | 2002 |
Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures.
Topics: Acetates; Alanine; Aminooxyacetic Acid; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamates; Glutamine; Ketoglutaric Acids; Penicillins; Pyruvates; Rats; Seizures; Time Factors; Transaminases | 1978 |
Effect of n-dipropylacetate on amino acid concentrations in mouse brain: correlations with anti-convulsant activity.
Topics: Animals; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Kinetics; Male; Mice; Noise; Seizures; Valproic Acid | 1978 |
Cerebral permeability phenomena in epilepsy.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cell Membrane Permeability; Disease Models, Animal; Extracellular Space; Histidine; Methionine; Mice; Pentylenetetrazole; Rabbits; Seizures | 1976 |
Amino acid uptake in vivo by the mouse brain and by various regions of the rabbit brain after drug-induced convulsions.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Blood-Brain Barrier; Brain; Caudate Nucleus; Cerebral Cortex; Histidine; Hypothalamus; Isoleucine; Male; Mesencephalon; Methionine; Mice; Pentylenetetrazole; Phenylalanine; Rabbits; Seizures; Taurine; Thalamus | 1975 |
Hypoxia increases extracellular concentrations of excitatory and inhibitory neurotransmitters in subsequently induced seizure: in vivo microdialysis study in the rabbit.
Topics: Animals; Aspartic Acid; Bicuculline; Brain; Dialysis; Electroencephalography; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypoxia; Kinetics; Rabbits; Reference Values; Seizures; Taurine; Time Factors | 1992 |
Kindling increases brain levels of NAAG and seizures reduce activity of a NAAG-hydrolyzing enzyme, NAALADase.
Topics: Amygdala; Animals; Aspartic Acid; Brain; Brain Mapping; Dipeptidases; Dipeptides; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate Carboxypeptidase II; Glutamates; Glutamic Acid; Kindling, Neurologic; Male; Rats; Rats, Sprague-Dawley; Seizures | 1992 |
Limbic seizure-induced changes in extracellular amino acid levels in the hippocampal formation: a microdialysis study of freely moving rats.
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Brain Mapping; Chromatography, High Pressure Liquid; Dialysis; Extracellular Space; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Limbic System; Male; Rats; Rats, Wistar; Seizures; Serine; Synaptic Transmission | 1992 |
Seizure related elevations of extracellular amino acids in human focal epilepsy.
Topics: Amino Acids; Asparagine; Aspartic Acid; Cerebral Cortex; Dialysis; Electroencephalography; Epilepsies, Partial; Extracellular Space; Glutamates; Glycine; Humans; Seizures; Serine | 1992 |
[Sequential changes in content of excitatory amino acids in the epileptic focus during seizure].
Topics: Amino Acids; Amygdala; Animals; Aspartic Acid; Cats; Dialysis; Epilepsies, Partial; Extracellular Space; Glutamates; Glutamic Acid; Kindling, Neurologic; Seizures | 1991 |
Sequential changes in content of excitatory amino acids in the focus of epilepsy in seizure induction.
Topics: Amygdala; Animals; Aspartic Acid; Cats; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy; Evoked Potentials; Glutamates; Glutamic Acid; Kindling, Neurologic; Seizures | 1991 |
Modulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex.
Topics: Acoustic Stimulation; Animals; Aspartic Acid; Diazepam; Injections, Intraventricular; Ion Channels; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Piperazines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine | 1990 |
Amino acid neurotransmitter alterations in three sublines of Rb mice differing by their susceptibility to audiogenic seizures.
Topics: Acoustic Stimulation; Amino Acids; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Male; Mice; Mice, Mutant Strains; Neurotransmitter Agents; Seizures; Taurine; Temporal Lobe; Tissue Distribution | 1990 |
Aspartic acid release from cerebral cortical slices of E1 mice with high seizure susceptibility.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; Mice; Mice, Mutant Strains; Potassium; Seizures | 1990 |
Effects evoked by pentamethylenetetrazol-induced seizures upon N-acetylaspartate and N-acetylaspartylglutamate levels in different regions of the rat neuraxis.
Topics: Animals; Aspartic Acid; Brain; Brain Stem; Dipeptides; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Spinal Cord | 1991 |
Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative.
Topics: 4-Butyrolactone; Acoustic Stimulation; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dopamine; Furans; Glycine; In Vitro Techniques; Isomerism; Kinetics; Male; Membrane Potentials; Mice; Mice, Inbred DBA; Motor Activity; N-Methylaspartate; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Seizures; Serotonin | 1990 |
Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glycine; Kainic Acid; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Phencyclidine; Pyrrolidinones; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1990 |
Evidence against an involvement of the haloperidol-sensitive sigma recognition site in the discriminative stimulus properties of (+)-N-allylnormetazocine ((+)-SKF 10,047).
Topics: Animals; Aspartic Acid; Binding, Competitive; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Guanidines; Haloperidol; Male; Mice; N-Methylaspartate; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1990 |
In vivo interaction of a polyamine with the NMDA receptor.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; N-Methylaspartate; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Spermidine | 1990 |
Magnesium reduces N-methyl-D-aspartate (NMDA)-mediated brain injury in perinatal rats.
Topics: Animals; Aspartic Acid; Brain; Corpus Striatum; Dose-Response Relationship, Drug; Magnesium; Microinjections; N-Methylaspartate; Neurotoxins; Organ Size; Rats; Rats, Inbred Strains; Seizures | 1990 |
Conantokin-T. A gamma-carboxyglutamate containing peptide with N-methyl-d-aspartate antagonist activity.
Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Animals; Aspartic Acid; Benzofurans; Calcium; Cerebellum; Chromatography, Gel; Conotoxins; Fluorescent Dyes; Fura-2; Intercellular Signaling Peptides and Proteins; Mass Spectrometry; Mice; Molecular Sequence Data; Mollusk Venoms; N-Methylaspartate; Neurons; Peptides; Rats; Seizures; Sequence Homology, Nucleic Acid; Snails | 1990 |
Antagonism between intracerebroventricularly administered N-methyl-D-aspartate and bicuculline methiodide in induction of clonic seizures in mice.
Topics: Animals; Aspartic Acid; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Seizures | 1990 |
Comparison of anticonvulsant effect of ethanol against NMDA-, kainic acid- and picrotoxin-induced convulsions in rats.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Synergism; Ethanol; Kainic Acid; Male; N-Methylaspartate; Picrotoxin; Rats; Rats, Inbred Strains; Seizures | 1990 |
Anticonvulsant profile of the dihydropyridine calcium channel antagonists, nitrendipine and nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Aspartic Acid; Atmospheric Pressure; Calcium Channel Blockers; Electrophysiology; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Strychnine | 1988 |
In vivo labelling of the NMDA receptor channel complex by [3H]MK-801.
Topics: Affinity Labels; Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Binding, Competitive; Dibenzocycloheptenes; Dioxolanes; Dizocilpine Maleate; Ion Channels; Male; Mice; N-Methylaspartate; Phenazocine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Brain; Brain Ischemia; Cerebral Ventricles; Corpus Striatum; Electric Conductivity; Female; Gerbillinae; In Vitro Techniques; Male; Membranes; N-Methylaspartate; Oocytes; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Xenopus | 1989 |
The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor.
Topics: Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Binding, Competitive; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Male; Motor Activity; N-Methylaspartate; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1989 |
Glutamate receptor agonists increase the expression of Fos, Fra, and AP-1 DNA binding activity in the mammalian brain.
Topics: Animals; Anticonvulsants; Aspartic Acid; Binding, Competitive; Blotting, Northern; Convulsants; DNA-Binding Proteins; Electroshock; Gene Expression Regulation; Immunoblotting; Kainic Acid; Male; Mice; Mice, Inbred BALB C; N-Methylaspartate; Nucleic Acid Hybridization; Pentylenetetrazole; Picrotoxin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Seizures; Transcription Factors | 1989 |
Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Catalepsy; Globus Pallidus; Male; N-Methylaspartate; Nervous System Diseases; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Substantia Nigra; Syndrome | 1989 |
Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker.
Topics: Animals; Aspartic Acid; Cell Membrane; Cerebral Cortex; Dronabinol; Heart Rate; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Stereotyped Behavior; Tremor | 1989 |
A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties.
Topics: Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Cortical Spreading Depression; Female; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pregnancy; Pyrrolidinones; Quinoxalines; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine | 1989 |
A slow NMDA-mediated synaptic potential underlies seizures originating from midbrain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Bicuculline; In Vitro Techniques; Inferior Colliculi; N-Methylaspartate; Picrotoxin; Rats; Seizures; Valine | 1989 |
NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine | 1989 |
Convulsions induced by centrally administered NMDA in mice: effects of NMDA antagonists, benzodiazepines, minor tranquilizers and anticonvulsants.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Binding, Competitive; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Seizures | 1989 |
Homocysteic acid: convulsant action of stereoisomers in mice.
Topics: Animals; Aspartic Acid; Convulsants; Homocysteine; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Seizures; Stereoisomerism | 1989 |
Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline.
Topics: Animals; Anticonvulsants; Aspartic Acid; Brain; Cyclohexylamines; Isoquinolines; Male; Mice; Motor Activity; N-Methylaspartate; Phencyclidine; Seizures; Tetrahydroisoquinolines | 1989 |
Non-competitive N-methyl-D-aspartate antagonists protect against sound-induced seizures in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Body Temperature; Female; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Seizures; Time Factors | 1989 |
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |
A comparison of PCP-like compounds for NMDA antagonism in two in vivo models.
Topics: Animals; Aspartic Acid; Behavior, Animal; Dioxolanes; Dioxoles; Ketamine; Male; Mice; Motor Activity; N-Methylaspartate; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Inhibition of aminophylline-induced convulsions in mice by antiepileptic drugs and other agents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminophylline; Animals; Anticonvulsants; Aspartic Acid; Diazepam; Female; Mice; N-Methylaspartate; Phenobarbital; Seizures; Synaptic Transmission; Valproic Acid | 1987 |
Paradoxical convulsant action of a novel non-competitive N-methyl-D-aspartate (NMDA) antagonist, tiletamine.
Topics: Animals; Anticonvulsants; Aspartic Acid; Cyclohexanes; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reflex, Monosynaptic; Seizures; Tiletamine | 1988 |
CGS 19755 is a potent and competitive antagonist at NMDA-type receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Binding, Competitive; Blood-Brain Barrier; Cerebellum; Cyclic GMP; Harmaline; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Kainic Acid; Male; N-Methylaspartate; Olfactory Bulb; Oxadiazoles; Pilocarpine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Reference Values; Seizures | 1988 |
Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist?
Topics: Animals; Anticonvulsants; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Seizures; Stereoisomerism | 1985 |
Effects of two convulsant beta-carboline derivatives, DMCM and beta-CCM, on regional neurotransmitter amino acid levels and on in vitro D-[3H]aspartate release in rodents.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Carbolines; Cerebellum; Cerebral Cortex; Convulsants; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamine; Hippocampus; Indoles; Male; Mice; Mice, Inbred DBA; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Seizures | 1985 |
Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders.
Topics: Adult; Amino Acids; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Glutamates; Humans; Hypoxia, Brain; Infant; N-Methylaspartate; Nerve Degeneration; Neurotransmitter Agents; Quinolinic Acids; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1985 |
A dipeptide derived from kainic and L-glutamic acids: a selective antagonist of amino acid induced neuroexcitation with anticonvulsant properties.
Topics: Animals; Aspartic Acid; Cell Membrane Permeability; Corpus Striatum; Dipeptides; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Picrotoxin; Quisqualic Acid; Rats; Seizures; Sodium | 1985 |
[Effect of excitant amino acid antagonists on glutamate receptors in the locust and on convulsions induced by glutamate, aspartate, kynurenine and quinolinic acid in mice].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutamates; Glutamic Acid; Grasshoppers; Kynurenine; Male; Membrane Potentials; Mice; Muscles; Pyridines; Quinolinic Acid; Quinolinic Acids; Receptors, Glutamate; Receptors, Neurotransmitter; Seizures | 1986 |
Absence of side-effects in the anticonvulsant action of cortically applied antagonists of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dipeptides; Morphine; N-Methylaspartate; Picrotoxin; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Strychnine; Valine | 1986 |
Role of excitatory amino acid transmission in the genesis of seizures elicited from the deep prepiriform cortex.
Topics: Animals; Aspartic Acid; Bicuculline; Carbachol; Glutamates; Glutamic Acid; Kainic Acid; Limbic System; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Seizures | 1986 |
On the role of seizure activity and endogenous excitatory amino acids in mediating seizure-associated hippocampal damage.
Topics: Acetylcholine; Action Potentials; Amino Acids; Animals; Aspartic Acid; Cell Survival; Dendrites; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Kainic Acid; Neurotransmitter Agents; Seizures; Time Factors | 1986 |
Toxicology of tremorgenic mycotoxins, fumitremorgin A and B.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Haloperidol; Harmine; Indenes; Indoles; Lethal Dose 50; Male; Mice; Perphenazine; Posture; Reserpine; Seizures; Spiperone; Triflupromazine | 1986 |
CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.
Topics: Acetylcholine; Animals; Aspartic Acid; Cerebellum; Corpus Striatum; Cyclic GMP; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1987 |
Amino acid influences on seizures elicited within the inferior colliculus.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Inferior Colliculi; Male; Muscimol; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Taurine | 1987 |
Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Antitussive Agents; Aspartic Acid; Cerebral Cortex; Dextromethorphan; Dextrorphan; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Levorphanol; Morphinans; N-Methylaspartate; Seizures; Valine | 1988 |
CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist.
Topics: Acetylcholine; Aconitine; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Binding, Competitive; Darkness; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Pipecolic Acids; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Structure-Activity Relationship; Tetrodotoxin | 1988 |
Glycine potentiates strychnine-induced convulsions: role of NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Drug Synergism; Glycine; Injections, Spinal; Mice; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Strychnine; Valine | 1988 |
Intrastriatal N-methyl-D-aspartate prevents amygdala kindled seizures in rats.
Topics: Amygdala; Animals; Aspartic Acid; Corpus Striatum; Depression, Chemical; Kindling, Neurologic; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1986 |
Excitatory neurotransmission within substantia nigra pars reticulata regulates threshold for seizures produced by pilocarpine in rats: effects of intranigral 2-amino-7-phosphonoheptanoate and N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Electroencephalography; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Stereotaxic Techniques; Substantia Nigra; Synaptic Transmission | 1986 |
The effect of two novel dipeptide antagonists of excitatory amino acid neurotransmission on the high pressure neurological syndrome in the rat.
Topics: Animals; Aspartic Acid; Central Nervous System Diseases; Glutamates; Glutamine; High Pressure Neurological Syndrome; Kainic Acid; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1987 |
Dextromethorphan inhibits NMDA-induced convulsions.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dextromethorphan; Dibenzocycloheptenes; Dizocilpine Maleate; Levorphanol; Male; Mice; N-Methylaspartate; Psychomotor Performance; Seizures | 1988 |
Neurotoxicity of N-methyl-D-aspartate is markedly enhanced in developing rat central nervous system.
Topics: Aging; Animals; Aspartic Acid; Corpus Striatum; Hippocampus; Microinjections; N-Methylaspartate; Neurotoxins; Rats; Rats, Inbred Strains; Seizures | 1988 |
Regulation of seizure threshold by excitatory amino acids in the striatum and entopeduncular nucleus of rats.
Topics: Animals; Aspartic Acid; Corpus Striatum; Globus Pallidus; Kainic Acid; Male; N-Methylaspartate; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1988 |
In vivo brain dialysis of amino acids and simultaneous EEG measurements following intrahippocampal quinolinic acid injection: evidence for a dissociation between neurochemical changes and seizures.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Electroencephalography; gamma-Aminobutyric Acid; Glutamine; Glycine; Hippocampus; Humans; Injections, Intraventricular; Male; Niacin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Taurine | 1985 |
2-Amino-7-phosphonoheptanoic acid inhibits insulin-induced convulsions and striatal aspartate accumulation in rats with frontal cortical ablation.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Blood Glucose; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Glucose; Insulin; Male; Rats; Rats, Inbred Strains; Seizures | 1987 |
Induction of audiogenic seizure susceptibility by focal infusion of excitant amino acid or bicuculline into the inferior colliculus of normal rats.
Topics: Acoustic Stimulation; Animals; Aspartic Acid; Bicuculline; Inferior Colliculi; Male; Microinjections; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Superior Colliculi | 1986 |
Method of lesioning brainstem determines seizure probability.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Stem; Electric Injuries; Hot Temperature; Male; N-Methylaspartate; Neurology; Rats; Rats, Inbred Strains; Seizures | 1986 |
A simple method for quantitative electroencephalographic assessment of drugs with convulsant and anticonvulsant properties.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Convulsants; Diazepam; Electroencephalography; Hippocampus; Injections; Kainic Acid; Male; N-Methylaspartate; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1986 |
Unusual interactions of excitatory amino acid receptor agonists: alpha- and beta-kainate antagonize motor responses to N-methyl-D-aspartate in rodents.
Topics: Animals; Aspartic Acid; Electromyography; Kainic Acid; Male; Mice; Motor Activity; Muscle Spasticity; Muscle Tonus; N-Methylaspartate; Seizures; Stereoisomerism | 1987 |
Antagonism of N-methyl-D,L-aspartic acid-induced convulsions by antiepileptic drugs and other agents.
Topics: Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Subcutaneous; Male; Mice; N-Methylaspartate; Seizures | 1985 |
Anticonvulsant activity of two novel piperazine derivatives with potent kainate antagonist activity.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Kainic Acid; Mice; Mice, Inbred DBA; Mice, Inbred Strains; N-Methylaspartate; Oxadiazoles; Piperazines; Pyrrolidines; Quinolinic Acids; Quisqualic Acid; Seizures | 1985 |
Azotomycin--toxicologic, biochemical and pharmacologic studies in mice.
Topics: Animals; Antibiotics, Antineoplastic; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Ataxia; Azo Compounds; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Diarrhea; DNA; Formates; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Lethal Dose 50; Ligases; Liver Neoplasms; Malate Dehydrogenase; Mice; Mice, Inbred Strains; Protein Biosynthesis; Seizures; Spleen; Time Factors | 1974 |
Regulation of glycolysis in brain, in situ, during convulsions.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Brain; Brain Chemistry; Central Nervous System Stimulants; Citrates; Glutamates; Glycogen; Glycolysis; Hexokinase; Hexosephosphates; In Vitro Techniques; Lactates; Mice; Phosphocreatine; Phosphofructokinase-1; Seizures | 1966 |
[Mutal inhibitory effect between chlorpromazine and several convulsants on convulsion].
Topics: Aminobutyrates; Animals; Aspartic Acid; Central Nervous System Stimulants; Chlorpromazine; Dogs; Drug Antagonism; Glutamates; Injections; Injections, Intravenous; Methionine; Pentylenetetrazole; Seizures | 1971 |
[Mechanism of intrahepatic accumulation of dicarboxylic amino acids during ammonia poisoning].
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Citrates; Citrulline; Dicarboxylic Acids; Glutamates; Glutaminase; Glutamine; Liver; Malates; Ornithine; Pyruvates; Rats; Seizures; Urea | 1972 |
Glutamate and aspartate in cortical subarachnoid fluid in relation to convulsive activity.
Topics: Animals; Aspartic Acid; Azoles; Brain; Dogs; Glutamates; Methionine Sulfoximine; Picrotoxin; Seizures; Subarachnoid Space; Thiosemicarbazones | 1973 |
The effect of hexafluorodiethyl ether (flurothyl) on the metabolism of rat brain amino acids labelled by (U-14C)glucose.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Carbon Radioisotopes; Chromatography, Ion Exchange; Citric Acid Cycle; Ethyl Ethers; Fluorine; Glucose; Glutamates; Glutamine; Male; Myoclonus; Rats; Seizures; Time Factors | 1973 |
Brain amino acids during convulsions.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Electric Stimulation; Glutamates; Glutamine; Ketoglutaric Acids; Male; Mice; Phenobarbital; Seizures; Spectrometry, Fluorescence; Time Factors | 1974 |
Incorporation of carbon from glucose into cerebral amino acids, proteins and lipids, and alterations during recovery from hypoglycaemia.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cerebral Cortex; Cerebrosides; Cholesterol; Dogs; Electroencephalography; Gangliosides; Glucose; Glutamates; Glutamine; Hypoglycemia; Insulin; Lipid Metabolism; Male; Nerve Tissue Proteins; Phosphatidylethanolamines; Seizures; Serine | 1972 |
[Experimental seizures caused by derivatives of glutamic acid].
Topics: Adipates; Amines; Aminocaproates; Animals; Aspartic Acid; Cats; Cysteine; Dogs; Female; Glutamates; Injections; Ketoglutaric Acids; Male; Pimelic Acids; Rats; Rats, Inbred Strains; Seizures; Succinates | 1972 |
Effects of excitation and anaesthesia on the glutamine content of the rat brain with a reference to the administration of glutamine.
Topics: Ammonia; Animals; Aspartic Acid; Brain; Brain Chemistry; Delirium; Glutamates; Glutamine; Head; Humans; Male; Pentobarbital; Pentylenetetrazole; Rats; Seizures; Tissue Extracts; Trichloroacetic Acid | 1972 |
The toxicity of monosodium glutamate in young rats.
Topics: Age Factors; Animals; Aspartic Acid; Brain Chemistry; Glutamates; Glutamine; Glycine; Injections, Intraperitoneal; Intubation, Gastrointestinal; Rats; Seizures; Sodium; Stereoisomerism | 1971 |
Effects of various conditions on the movement of carbon atoms derived from glucose into and out of protein in rat brain.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Brain; Carbon Isotopes; Cerebral Cortex; Depression, Chemical; Glucose; Glutamates; Hypoxia; Injections, Intravenous; Insulin; Male; Metabolism; Nerve Tissue Proteins; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stimulation, Chemical; Time Factors | 1970 |
Incorporation of carbon atoms from glucose into free amino acids in brain under normal and altered conditions.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Autoanalysis; Brain; Carbon Isotopes; Depression, Chemical; Glucose; Glutamates; Glutamine; Glycolates; Hypoxia; Injections, Intravenous; Lactates; Male; Metabolism; Methods; Pentobarbital; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stimulation, Chemical; Time Factors | 1970 |
[Introduction of mass psychology of animals to pharmacology. IV. Biorhythm in convulsive seizure].
Topics: Animals; Aspartic Acid; Atmospheric Pressure; Biological Clocks; Electroshock; Mice; Psychology; Seizures; Time Factors | 1970 |
Protein-bound amide groups in brain.
Topics: Amides; Ammonia; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Cerebral Cortex; Glucose; Glutamates; Glutamine; Hydrochloric Acid; Nerve Tissue Proteins; Pentobarbital; Peptide Hydrolases; Picrotoxin; Protein Binding; Rats; Seizures; Streptomyces | 1970 |
[Changes in the levels of gamma-aminobutyric, glutamic and aspartic acids and glutamine in primary and reflected foci of epileptic activity].
Topics: Aminobutyrates; Animals; Aspartic Acid; Brain Chemistry; Electroencephalography; Epilepsy; Glutamates; Glutamine; Rabbits; Seizures | 1970 |
[Protective action of N-acetylaspartic acid and N-acetylaspartyl-glutamic acid in convulsive seizures induced with pentamethylene-tetrazole in rats].
Topics: Acetates; Aspartic Acid; Brain; Glutamates; Pentylenetetrazole; Seizures | 1970 |
Some neurochemical aspects of fluorocitrate intoxication.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Aminobutyrates; Ammonia; Animals; Aspartic Acid; Brain; Carbon Isotopes; Cats; Central Nervous System; Chromatography, Paper; Citrates; Colorimetry; Female; Fluorine; Glucose; Glutamates; Glutamine; Glycogen; Kidney; Liver; Lysine; Nerve Tissue Proteins; Poisoning; Rats; Seizures; Spectrophotometry; Spinal Cord | 1971 |
Amino acid changes in the mouse brain during audiogenic seizures and recovery.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Glutamates; Glutamine; Mice; Seizures; Sound; Time Factors | 1968 |
[Argininosuccinic aciduria disease of the newborn with lethal course].
Topics: Adult; Alanine; Amino Acids; Aminobutyrates; Anticonvulsants; Aspartic Acid; Brain Diseases; Chromatography, Ion Exchange; Chromatography, Thin Layer; Erythrocytes; Female; Glutamine; Hepatomegaly; Humans; Infant, Newborn; Kidney Diseases; Lyases; Male; Metabolism, Inborn Errors; Myocardium; Seizures; Succinates; Transaminases | 1968 |
[Metabolic investigations of epileptic seizures. The activity of the glutamate decarboxylase prior to and during experimentally produced convulsions].
Topics: Animals; Aspartic Acid; Brain; Carboxy-Lyases; Electroshock; Female; Glutamates; In Vitro Techniques; Male; Noise; Pentylenetetrazole; Pyridoxal Phosphate; Rats; Seizures | 1968 |
Electroshock-induced seizures and the turnover of brain protein in the rat.
Topics: Animals; Aspartic Acid; Body Weight; Brain; Carbon Isotopes; Chromatography; Electroshock; Glucose; Glutamates; Lipid Metabolism; Liver; Male; Nerve Tissue Proteins; Nucleic Acids; Rats; Seizures | 1968 |
[Metabolic investigations of epileptic seizures: the role of aminotransferases and glutamate dehydrogenase in convulsions].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspartic Acid; Azoles; Brain; Electroshock; Female; Glutamate Dehydrogenase; Glutamates; Male; Phosphates; Rats; Seizures; Transaminases | 1969 |
The neurotoxicity of beta-N-oxalyl-L-alphabeta-diaminopropionic acid, the neurotoxin from the pulse Lathyrus sativus.
Topics: Age Factors; Ammonia; Animals; Aspartic Acid; Brain; Brain Chemistry; Glutamates; Glutamine; Injections, Intraperitoneal; Lathyrism; Liver; Propionates; Rats; Seizures; Toxins, Biological; Urea | 1969 |
[Metabolic studies of epileptic seizures. The concentration of free amino acids in cerebral tissue prior to and during cerebral seizures].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Centrifugation; Chromatography, Paper; Electroshock; Female; Glutamates; Glutamine; Male; Noise; Pentylenetetrazole; Phosphates; Rats; Seizures | 1969 |
[Action of insulin on the amino acid content and enzymatic activity of the pigeon brain].
Topics: Alanine Transaminase; Aminobutyrates; Animals; Aspartate Aminotransferases; Aspartic Acid; Birds; Brain; Brain Chemistry; Carboxy-Lyases; Glutamates; Glutamine; Insulin; Seizures | 1964 |
The measurement of free and N-acetylated aspartic acids in the nervous system.
Topics: Animals; Aspartic Acid; Biological Assay; Brain Chemistry; Fluorometry; Histocytochemistry; In Vitro Techniques; Insulin; Mice; Rabbits; Seizures; Spectrophotometry | 1966 |
Carbamylaspartate, a new agent against acute ammonia intoxication.
Topics: Ammonia; Animals; Aspartic Acid; Carbamates; Male; Mortality; Rats; Seizures | 1966 |