asparagine and Pancreatic Neoplasms

asparagine has been researched along with Pancreatic Neoplasms in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's5 (33.33)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Hu, J; Li, G; Lu, Y; Wang, Z; Yang, S1
Curukovic, A; DeBerardinis, RJ; Huerta-Rosario, M; Jeong, MH; Jewell, JL; Lama-Sherpa, TD; Lewis, C; Melick, CH; Meng, D; Tiwary, S; Urquhart, G; Wang, H; Yang, Q; Zacharias, LG1
Anaraki, C; Andren, A; Batra, S; Beard, DA; Beutel, AK; Boyer, S; Christofk, HR; Crawford, HC; Digman, MA; Felton, C; Halbrook, CJ; Hong, HS; Jiménez, JA; Jorgensen, C; Kerk, SA; Krall, AS; Law, FV; Lin, L; Lyssiotis, CA; McCarthy, A; Morton, JP; Mullen, PJ; Nelson, BS; Pasca di Magliano, M; Sajjakulnukit, P; Scipioni, L; Singh, R; Stanger, BZ; Steele, NG; Thurston, G; Van Den Bergh, F; Viale, A; Zhang, J; Zhang, L1
Augustine, JJ; Dai, B; Deng, J; Fleming, JB; Kang, Y; Kim, MP; Li, X; Lorenzi, PL; Roife, D; Rusling, LA; Tan, L; Weinstein, JN1
Azuma, T; Goto, A; Hidaka, A; Hirata, Y; Inoue, M; Iwasaki, M; Kobayashi, T; Nakagawa, T; Nishiumi, S; Sawada, N; Shimazu, T; Tsugane, S; Yamaji, T; Yamanaka, K; Yoshida, M1
Nakata, D1
Fukutake, N; Hiraoka, N; Imaizumi, A; Ito, T; Katayama, K; Kikuchi, S; Ono, N; Saruki, N; Shimada, K; Shiraishi, K; Ueno, M; Yamakado, M; Yamamoto, H1
Aguera, K; Dufour, E; Gay, F; Godfrin, Y; Horand, F; Lorenzi, PL; Scoazec, JY1
Chen, CR; Kodra, JT; Liu, X; Yu, R1
Abbruzzese, JL; Bondy, ML; Evans, DB; Hassan, MM; Jiao, L; Li, D1
Asaka, M; Cui, H; Darmanin, S; Hamuro, J; Higashino, F; Kobayashi, M; Koide, H; Kondo, T; Nakagawa, K; Natsuisaka, M; Okada, F; Shindoh, M1
Dermadi Bebek, D; Greenblatt, M; Nyström, M; Ollila, S1
Heitz, PU; Klöppel, G; Komminoth, P; Li, WP; Roth, J; Zuber, C1
Arimura, GK; Wu, MC; Yunis, AA1
Freeze, HH; Kajiji, S; Quaranta, V; Sundblad, G; Varki, A1

Other Studies

15 other study(ies) available for asparagine and Pancreatic Neoplasms

ArticleYear
The edited UPF1 is correlated with elevated asparagine synthetase in pancreatic ductal adenocarcinomas.
    Molecular biology reports, 2022, Volume: 49, Issue:5

    Topics: Asparagine; Aspartate-Ammonia Ligase; beta-Globins; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Carcinoma, Pancreatic Ductal; Carrier Proteins; Humans; Mutagenesis, Site-Directed; Pancreatic Neoplasms; RNA Helicases; RNA, Messenger; Trans-Activators

2022
SNAT7 regulates mTORC1 via macropinocytosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 05-17, Volume: 119, Issue:20

    Topics: Amino Acid Transport Systems, Neutral; Asparagine; Glutamine; Humans; Lysosomes; Mechanistic Target of Rapamycin Complex 1; Pancreatic Neoplasms; Pinocytosis; Signal Transduction

2022
Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells.
    Nature cancer, 2022, Volume: 3, Issue:11

    Topics: Adenocarcinoma; Animals; Asparagine; Humans; Mice; Pancreatic Neoplasms; Symbiosis; Tumor Microenvironment

2022
Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway.
    Cell death & disease, 2021, 07-10, Volume: 12, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Asparagine; Aspartate-Ammonia Ligase; Cell Line, Tumor; Cell Proliferation; Elongation Factor 2 Kinase; Humans; Mice, Inbred NOD; Mice, SCID; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Pancreatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2021
Metabolome analysis for pancreatic cancer risk in nested case-control study: Japan Public Health Center-based prospective Study.
    Cancer science, 2018, Volume: 109, Issue:5

    Topics: Adult; Aged; Asparagine; Case-Control Studies; Deoxyglucose; Female; Humans; Logistic Models; Male; Metabolome; Methionine; Middle Aged; Pancreatic Neoplasms; Prospective Studies; Risk

2018
Increased N-glycosylation of Asn⁸⁸ in serum pancreatic ribonuclease 1 is a novel diagnostic marker for pancreatic cancer.
    Scientific reports, 2014, Oct-22, Volume: 4

    Topics: Animals; Asparagine; Biomarkers, Tumor; Glycosylation; Humans; Mice; Pancreatic Neoplasms; Ribonuclease, Pancreatic

2014
A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Area Under Curve; Asparagine; Body Mass Index; Cross-Sectional Studies; Early Detection of Cancer; Fasting; Female; Histidine; Humans; Isoleucine; Japan; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis, Chronic; ROC Curve; Serine; Tryptophan; Young Adult

2015
Pancreatic tumor sensitivity to plasma L-asparagine starvation.
    Pancreas, 2012, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Erythrocytes; Humans; Immunohistochemistry; Injections, Intravenous; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2012
Rescue of a pathogenic mutant human glucagon receptor by pharmacological chaperones.
    Journal of molecular endocrinology, 2012, Volume: 49, Issue:2

    Topics: Alanine; Asparagine; Cell Membrane; Curcumin; Cyclic AMP; Drug Design; Glucagon; Green Fluorescent Proteins; HEK293 Cells; Humans; Molecular Chaperones; Mutation; Pancreatic Neoplasms; Protein Transport; Pyridines; Pyrroles; Receptors, Glucagon; Serine; Thapsigargin

2012
The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk.
    Cancer letters, 2007, Jan-08, Volume: 245, Issue:1-2

    Topics: Adenocarcinoma; Aged; Amino Acid Substitution; Asparagine; Aspartic Acid; Carcinoma, Pancreatic Ductal; Case-Control Studies; Female; Gene Frequency; Genotype; Glutamine; Haplotypes; Humans; Linkage Disequilibrium; Lysine; Male; Middle Aged; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Xeroderma Pigmentosum Group D Protein

2007
Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin.
    Cancer research, 2007, Apr-01, Volume: 67, Issue:7

    Topics: Apoptosis; Asparagine; Aspartate-Ammonia Ligase; Cell Line, Tumor; Cisplatin; Fluorouracil; Gene Expression Regulation, Neoplastic; Glucose; Humans; JNK Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; RNA, Small Interfering; Transfection

2007
Uncertain pathogenicity of MSH2 variants N127S and G322D challenges their classification.
    International journal of cancer, 2008, Aug-01, Volume: 123, Issue:3

    Topics: Asparagine; Aspartic Acid; Biliary Tract Neoplasms; Blotting, Western; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Mismatch Repair; DNA-Binding Proteins; Endometrial Neoplasms; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Glycine; Humans; Immunoprecipitation; MutS Homolog 2 Protein; Pancreatic Neoplasms; Serine; Uncertainty

2008
Can malignancy in insulinoma be predicted by the expression patterns of beta 1,6 branching of asparagine-linked oligosaccharides and polysialic acid of the neural cell adhesion molecule?
    Virchows Archiv : an international journal of pathology, 1996, Volume: 429, Issue:4-5

    Topics: Adult; Aged; Aged, 80 and over; Animals; Asparagine; Female; Humans; Immunohistochemistry; Insulinoma; Male; Middle Aged; Multicenter Studies as Topic; Neural Cell Adhesion Molecules; Oligosaccharides; Pancreas; Pancreatic Neoplasms; Phytohemagglutinins; Rats; Sialic Acids; Tumor Cells, Cultured

1996
Mechanism of sensitivity of cultured pancreatic carcinoma to asparaginase.
    International journal of cancer, 1978, Volume: 22, Issue:6

    Topics: Amino Acids; Asparaginase; Asparagine; Breast Neoplasms; Cell Line; Cell Survival; Cells, Cultured; DNA, Neoplasm; Escherichia coli; Female; Glutamine; Glycoproteins; Humans; Melanoma; Neoplasm Proteins; Pancreatic Neoplasms; RNA, Neoplasm; Vibrio

1978
Sulfated N-linked oligosaccharides in mammalian cells. III. Characterization of a pancreatic carcinoma cell surface glycoprotein with N- and O-sulfate esters on asparagine-linked glycans.
    The Journal of biological chemistry, 1988, Jun-25, Volume: 263, Issue:18

    Topics: Asparagine; Cell Membrane; Humans; Membrane Glycoproteins; Microscopy, Electron; Molecular Weight; Neuraminidase; Oligosaccharides; Pancreatic Neoplasms; Sulfuric Acids

1988