asparagine has been researched along with Neoplasms in 69 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 33 (47.83) | 18.7374 |
1990's | 2 (2.90) | 18.2507 |
2000's | 11 (15.94) | 29.6817 |
2010's | 16 (23.19) | 24.3611 |
2020's | 7 (10.14) | 2.80 |
Authors | Studies |
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Batra, S; Chen, C; Davé, U; Fan, J; Jiang, J; Kapur, R; Liu, Y; Misra, J; Seim, G; Srivastava, S; Staschke, KA; Wek, RC; Zhang, C; Zhang, J; Zhong, M; Zhou, J; Zhou, L | 1 |
Hlozkova, K; Safrhansova, L; Starkova, J | 1 |
Oda, K; Wlodawer, A | 1 |
Adams, CM; Cassel, TA; Chen, X; Fan, TW; Gnanaprakasam, JNR; Higashi, RM; Kang, S; Kushwaha, B; Lane, AN; Li, Z; Liu, L; Scott, DA; Wang, R; Wang, T; Xin, G; Yang, J; Zhang, J | 1 |
Cinar, B; Dolgner, T; Fehlhaber, B; Forster, M; Hinze, L; Ibrahim, NK; Loxha, L; Niessen, J; Schreek, S; Stanulla, M; Stasche, AS | 1 |
Chang, JH; Mou, CY; Mou, KY | 1 |
Jiao, S; Wang, J; Wang, M; Wang, R; Wang, S; Zhang, J; Zhang, M | 1 |
Harada, Y; Kizuka, Y; Ohkawa, Y; Taniguchi, N | 1 |
Christofk, HR; Halbrook, CJ; Knott, SRV; Krall, AS; Lyssiotis, CA; Mittelman, SD; Momcilovic, M; Mullen, PJ; Schmid, EW; Shackelford, DB; Surjono, F; Thambundit, A | 1 |
Bailly, C; Vergoten, G | 1 |
Eoh, H; Gao, SJ; Jung, JU; Lee, JJ; Li, T; Lu, C; Ramos da Silva, S; Zhu, Y | 1 |
Ho, M; Lemichez, E; Mettouchi, A; Wilson, BA | 1 |
Bitencourt-Ferreira, G; de Azevedo, WF; Souto, AA; Volkart, PA | 1 |
Hay, N; Terry, AR | 1 |
Ann, J; Apfel, V; Barretina, J; Clish, CB; Deik, A; Galli, GG; Garraway, LA; Ghandi, M; Giannakis, M; Gopal, S; Hahn, WC; Hernandez, D; Keskula, P; Kryukov, GV; Li, H; Ning, S; Pagliarini, RA; Pierce, K; Root, DE; Schreiber, SL; Sellers, WR; Shkoza, D; Souza, A; Tsherniak, A; Vazquez, F; Zou, Y | 1 |
Balasubramanian, MN; Butterworth, EA; Kilberg, MS | 1 |
Chen, CY; Chen, HY; Chen, KB; Chen, KC | 1 |
Chen, CY; Chen, HY; Chen, KC; Lee, WY | 1 |
Cooper, AJ; Denton, TT; Deryabina, YI; Dorai, T; Isakova, EP; Krasnikov, BF; Pinto, JT; Shurubor, YI | 1 |
Kim, HD; Kim, J; Kim, Y; Lee, MS | 1 |
Fellinger, K; Gires, O; Hofmann, T; Munz, M; Schmitt, B | 1 |
Bogyo, M; Lee, J | 1 |
ERRERA, M; GREENSTEIN, JP | 1 |
Bussolati, O; Chiarelli, LR; Covini, D; Digilio, R; Pasquetto, MV; Scotti, C; Tardito, S; Valentini, G | 1 |
Li, C; Thompson, CB | 1 |
Ando, M; Hanioka, N; Jinno, H; Kaniwa, N; Minami, H; Ohtsu, A; Ozawa, S; Saeki, M; Sai, K; Saijo, N; Saito, Y; Sawada, J; Shirao, K; Tanaka-Kagawa, T; Yoshida, T | 1 |
MCCOY, TA; NEUMAN, RE | 1 |
MCCOY, TA; ORR, GR; PATTERSON, MK | 1 |
CHRISTENSEN, HN | 1 |
LORINCZ, AB; RYAN, WL | 1 |
SCHINDLER, R | 2 |
MASHBURN, LT; WRISTON, JC | 1 |
CONWAY, E; MCCOY, TA; PATTERSON, MK; WHITTLE, W | 1 |
KOEHLER, L; NIEPER, HA | 1 |
NIEPER, HA | 1 |
Fujii, Y; Fujimoto, Z; Horii, K; Mizuno, H; Morita, T; Okuda, D | 1 |
Friedman, M | 1 |
Gobel, BH | 1 |
Cohen, AD; Duan, F; Engelhorn, ME; Guevara-Patiño, JA; Houghton, AN; Liu, C; Merghoub, T; Rizzuto, G; Turk, MJ; Wolchok, JD | 1 |
Bronson, R; Edelmann, W; Fan, K; Kucherlapati, M; Kucherlapati, R; Kuraguchi, M; Lipkin, M; Nguyen, A; Wei, K; Yang, K | 1 |
Asahi, M; Lee, SH; Li, W; Miyoshi, E; Osumi, D; Takahashi, M; Taniguchi, N; Yokoe, S | 1 |
Coleman, PS; Lavietes, BB | 1 |
Berezov, TT | 1 |
Arkin, H; Holland, JF; Ohnuma, T | 1 |
Riley, V | 1 |
Riley, V; Spackman, DH | 1 |
Buckhaults, P; Chen, L; Fregien, N; Pierce, M | 1 |
Dorr, RT; Fanta, P; Hersh, EM; Salmon, SE; Taylor, CW | 1 |
Doi, H; Komatsu, H; Nishihira, T; Satomi, S | 1 |
Borella, LD; Camitta, BM; Holcenberg, JS; Ring, BJ | 1 |
Qian, JK; Wang, BZ; Wen, XL; Yang, GH; Zhang, RJ | 1 |
Dennis, JW; Laferté, S; Vanderelst, I | 1 |
Hersh, EM | 1 |
Canellos, GP; Cooney, DA; Hardesty, CT; Haskell, CM | 1 |
Daill, M; Fink, E; Kronberger, L; Schindler, R | 1 |
Oettgen, HF | 1 |
Cooney, DA; Handschumacher, RE | 1 |
Hayaishi, O; Honjo, T | 1 |
Jacobasch, KH | 1 |
Freeman, A; Holland, JF; Ohnuma, T; Sinks, LF | 1 |
Hersh, EM; Ohno, R | 1 |
Chaudhuri, TK; Winchell, HS | 1 |
Boyse, EA; Brodey, RS; Campbell, HA; Fidler, J; Old, LJ; Teller, JD | 1 |
Balis, ME; Krakoff, IH; Miller, HK; Salser, JS | 1 |
Balis, ME; Miller, HK; Salser, JS | 1 |
Menkès, G | 1 |
19 review(s) available for asparagine and Neoplasms
Article | Year |
---|---|
Targeting amino acid metabolism in cancer.
Topics: Amino Acids; Arginine; Asparagine; Cysteine; Humans; Methionine; Neoplasms | 2022 |
Overview of the Properties of Glutamic Peptidases That Are Present in Plant and Bacterial Pathogens and Play a Role in Celiac Disease and Cancer.
Topics: Asparagine; Bacteria; Celiac Disease; Glutamic Acid; Histidine; Humans; Neoplasms; Peptide Hydrolases | 2023 |
Oligosaccharyltransferase: A Gatekeeper of Health and Tumor Progression.
Topics: Amino Acid Sequence; Asparagine; Disease Progression; Drug Resistance, Neoplasm; Endoplasmic Reticulum; Glycosylation; Hexosyltransferases; Humans; Membrane Proteins; Neoplasms; Polysaccharides; Protein Processing, Post-Translational | 2019 |
CNF1-like deamidase domains: common Lego bricks among cancer-promoting immunomodulatory bacterial virulence factors.
Topics: Amidohydrolases; Asparagine; Bacterial Toxins; Computational Biology; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Glutamine; Immunologic Factors; Neoplasms; rac1 GTP-Binding Protein; Virulence Factors | 2018 |
Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review.
Topics: Asparagine; Binding Sites; Cellular Senescence; Crystallography, X-Ray; Cyclin-Dependent Kinase 2; Drug Design; Humans; Leucine; Models, Molecular; Neoplasms; Protein Kinase Inhibitors | 2019 |
Fuelling cancer cells.
Topics: Asparagine; Aspartic Acid; Disease Progression; Female; Humans; Lactic Acid; Male; Neoplasms; Oxygen Consumption; Proteins; Reference Values; Tumor Cells, Cultured; Tumor Microenvironment | 2019 |
Asparagine synthetase: regulation by cell stress and involvement in tumor biology.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Stress, Physiological; Unfolded Protein Response | 2013 |
ω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases.
Topics: Amidohydrolases; Animals; Asparagine; Glutamine; Humans; Hyperammonemia; Neoplasms; Nitrogen; Sulfur | 2016 |
Expanding targets for a metabolic therapy of cancer: L-asparaginase.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Drug Delivery Systems; Glutaminase; Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 2012 |
Chemistry, biochemistry, and safety of acrylamide. A review.
Topics: Acrylamide; Acrylic Resins; Alkylation; Animals; Asparagine; Environmental Exposure; Food Analysis; Food Handling; Humans; Maillard Reaction; Neoplasms; Nervous System; Reproduction; Risk Factors | 2003 |
Chemotherapy-induced hypersensitivity reactions.
Topics: Antineoplastic Agents; Asparagine; Drug Hypersensitivity; Humans; Neoplasms; Oncology Nursing; Platinum Compounds; Podophyllotoxin; Risk Assessment; Risk Factors; Taxoids | 2005 |
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cholesterol; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Glucose; Glutamates; Glutamic Acid; Glutamine; Lipid Bilayers; Liver Neoplasms, Experimental; Membrane Lipids; Mitochondria; Mitochondria, Liver; Models, Biological; Neoplasms; Oxygen Consumption; Phenotype; Purines; Pyrimidines; Pyruvates; Pyruvic Acid; Surface Properties | 1981 |
[Asparagine biosynthesis and tumor growth].
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases | 1982 |
Regulation of N-acetylglucosaminyltransferase V and Asn-linked oligosaccharide beta(1,6) branching by a growth factor signaling pathway and effects on cell adhesion and metastatic potential.
Topics: Animals; Asparagine; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Gene Expression Regulation, Enzymologic; Humans; N-Acetylglucosaminyltransferases; Neoplasm Metastasis; Neoplasms; Oligosaccharides; Signal Transduction | 1997 |
[Anti-cancer therapy with amino acid imbalance].
Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine | 2001 |
[L-asparaginase: A new principle in the chemotherapy of malignant neoplasms].
Topics: Animals; Antibodies; Asparaginase; Asparagine; Bone Marrow; Escherichia coli; Guinea Pigs; Humans; Leukemia, Lymphoid; Mice; Neoplasms; Serratia marcescens | 1969 |
L-asparaginase and L-asparagine metabolism.
Topics: Animals; Asparaginase; Asparagine; Chemical Phenomena; Chemistry; Dogs; Guinea Pigs; Humans; Mice; Neoplasms; Rats | 1970 |
[Nutritional requirement of cancer cells: inhibition of the growth of cancer cells by L-asparaginase].
Topics: Animals; Asparaginase; Asparagine; Escherichia coli; Guinea Pigs; Humans; Leukemia; Mutation; Neoplasms; Neoplasms, Experimental | 1970 |
[Enzyme therapy of malignant tumors].
Topics: Animals; Asparaginase; Asparagine; Glutaminase; Guinea Pigs; Humans; Leukemia; Mice; Neoplasms; Neoplasms, Experimental; Rabbits; Rats | 1969 |
2 trial(s) available for asparagine and Neoplasms
Article | Year |
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A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors.
Topics: Adult; Antineoplastic Agents; Asparaginase; Asparagine; Carcinoma, Non-Small-Cell Lung; Drug Screening Assays, Antitumor; Glutaminase; Humans; Lung Neoplasms; Melanoma; Neoplasm Proteins; Neoplasms; Polyethylene Glycols; Skin Neoplasms | 2001 |
Phase I study of succinylated acinetobacter L-glutaminase-L-asparaginase.
Topics: Acinetobacter; Adolescent; Alkalosis, Respiratory; Amidohydrolases; Asparagine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Female; Glutamine; Humans; Hyperglycemia; Leukemia, Lymphoid; Male; Neoplasms | 1979 |
48 other study(ies) available for asparagine and Neoplasms
Article | Year |
---|---|
Asparagine bioavailability regulates the translation of MYC oncogene.
Topics: 3' Untranslated Regions; Amino Acids; Animals; Asparagine; Biological Availability; Genes, myc; Mice; Neoplasms; Proto-Oncogene Proteins c-myc | 2022 |
Asparagine restriction enhances CD8
Topics: Animals; Asparagine; CD8-Positive T-Lymphocytes; Glucose; Neoplasms; NF-E2-Related Factor 2 | 2023 |
GSK3α Regulates Temporally Dynamic Changes in Ribosomal Proteins upon Amino Acid Starvation in Cancer Cells.
Topics: Amino Acids; Asparagine; Glycogen Synthase Kinase 3; Humans; Neoplasms; Protein Serine-Threonine Kinases; Ribosomal Proteins | 2023 |
Sleeping Beauty Transposon-Mediated Asparaginase Gene Delivery by a Nanoparticle Platform.
Topics: A549 Cells; Antineoplastic Agents; Asparaginase; Asparagine; Cell Survival; Cisplatin; Combined Modality Therapy; DNA Transposable Elements; Doxorubicin; Drug Carriers; Gene Transfer Techniques; Genetic Therapy; Humans; Nanoparticles; Neoplasms; Plasmids; Silicon Dioxide; Transfection; Transposases | 2019 |
Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Affinity; Antigen-Antibody Complex; Antineoplastic Agents, Immunological; Asparagine; B7-H1 Antigen; Binding, Competitive; Crystallography, X-Ray; Epitopes; Female; Glycosylation; Humans; Mice; Mice, Inbred C57BL; Models, Molecular; Neoplasms; Nivolumab; Programmed Cell Death 1 Ligand 2 Protein; Programmed Cell Death 1 Receptor; Protein Interaction Domains and Motifs | 2019 |
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth.
Topics: Activating Transcription Factor 4; Animals; Asparagine; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Diet; Electron Transport Chain Complex Proteins; Humans; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Inbred NOD; Mitochondria; Neoplasms; Nucleotides; Survival Rate | 2021 |
Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach.
Topics: Asparagine; Child; Chloroquine; Fatty Acids; Humans; Hydroxychloroquine; Membrane Proteins; Neoplasms; Neuronal Ceroid-Lipofuscinoses; Palmitates; Thiolester Hydrolases | 2022 |
A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus.
Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Cell Proliferation; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Herpesvirus 8, Human; Humans; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Nucleotides | 2017 |
The landscape of cancer cell line metabolism.
Topics: Animals; Asparaginase; Asparagine; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cell Line, Tumor; DNA Methylation; Female; Gene Knockdown Techniques; Humans; Kynurenine; Liver Neoplasms; Metabolome; Mice; Mice, Nude; Neoplasms; Stomach Neoplasms | 2019 |
In silico investigation of potential pyruvate kinase M2 regulators from traditional Chinese medicine against cancers.
Topics: Asparagine; Binding Sites; Carrier Proteins; Chemistry, Pharmaceutical; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Hydrogen Bonding; Ligands; Lysine; Medicine, Chinese Traditional; Membrane Proteins; Mitosis; Molecular Dynamics Simulation; Neoplasms; Protein Conformation; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Tryptophan | 2014 |
In silico investigation of potential TRAF6 inhibitor from traditional Chinese medicine against cancers.
Topics: Animals; Asparagine; Cattle; Crystallography, X-Ray; Diiodotyrosine; Humans; Hydrogen Bonding; Hypoxia-Inducible Factor 1, alpha Subunit; Ligands; Medicine, Chinese Traditional; Molecular Dynamics Simulation; Neoplasms; Neovascularization, Pathologic; Protein Binding; Protein Structure, Secondary; TNF Receptor-Associated Factor 6; Tryptophan | 2014 |
Asparagine protects tumor cells from glutamine depletion-induced cell death.
Topics: Asparagine; Aspartate-Ammonia Ligase; Cell Death; Glutamine; Humans; Neoplasms; Transcription Factor CHOP | 2014 |
Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated.
Topics: Animals; Asparagine; Brefeldin A; Cell Line, Tumor; Cell Movement; Endoplasmic Reticulum; Glycosylation; Golgi Apparatus; Humans; Mice; Monensin; Neoplasm Invasiveness; Neoplasms; NIH 3T3 Cells; Point Mutation; Protein Processing, Post-Translational; Protein Transport; Ribosomal Proteins; Transfection; Tunicamycin | 2016 |
Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM.
Topics: 3T3 Cells; Animals; Antigens, Neoplasm; Asparagine; Cell Adhesion Molecules; Cell Line; Epithelial Cell Adhesion Molecule; Glycoside Hydrolases; Glycosylation; Humans; Kidney; Mice; Mutation; Neoplasms | 2008 |
Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain.
Topics: Animals; Asparagine; Carbocyanines; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Epoxy Compounds; Fluorescent Dyes; Humans; Mice; Mice, Inbred Strains; Neoplasms; NIH 3T3 Cells; Spectroscopy, Near-Infrared; Xenograft Model Antitumor Assays | 2010 |
Desamidation of glutamine and asparagine in normal and neoplastic hepatic tissues.
Topics: Amino Acids; Asparagine; Glutamine; Liver Neoplasms; Neoplasms | 1947 |
Cancer. DNA damage, deamidation, and death.
Topics: Antineoplastic Agents; Apoptosis; Asparagine; Aspartic Acid; bcl-X Protein; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA, Neoplasm; Genes, p53; Genes, Retinoblastoma; Humans; Models, Biological; Mutation; Neoplasms; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Retinoblastoma Protein; Tumor Suppressor Protein p53 | 2002 |
Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Camptothecin; COS Cells; Exons; Genetic Variation; Glucuronates; Glucuronic Acid; Glucuronosyltransferase; Humans; Irinotecan; Japan; Mutation; Neoplasms; Polymorphism, Single Nucleotide; Transfection; UDP-Glucuronosyltransferase 1A9 | 2003 |
Dual requirement of Walker carcinosarcoma 256 in vitro for asparagine and glutamine.
Topics: Animals; Asparagine; Biochemical Phenomena; Carcinoma 256, Walker; Glutamine; Humans; In Vitro Techniques; Neoplasms | 1956 |
ASPARAGINE-C14 AND GLUTAMINE-C14 FROM ANIMAL CELL PROTEIN AND THEIR CHEMICAL DEGRADATION.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Glutamine; Ion Exchange Resins; Malates; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Proteins; Research; Sarcoma; Sarcoma, Experimental | 1963 |
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
QUANTITATIVE COLONIAL GROWTH OF MAMMALIAN CELLS IN FIBRIN CELLS.
Topics: Asparagine; Fibrin; Folic Acid; Immune Sera; Mast Cells; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Serine; Thrombin; Tissue Culture Techniques | 1964 |
TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Bacillus; Electrophoresis; Escherichia coli; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Experimental | 1964 |
IN VITRO EFFECTS OF GUINEA PIG SERUM ON THE JENSEN, JA-1 AND JA-2 SARCOMAS.
Topics: Amidohydrolases; Animals; Asparagine; Blood; Culture Media; Guinea Pigs; In Vitro Techniques; Metabolism; Neoplasms; Pharmacology; Research; Research Design; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques | 1965 |
[EXPERIMENTAL STUDIES AND CLINICAL USE OF ELECTROLYTE-CARRIER COMPOUNDS. 6. ORIENTATIONAL RESEARCH ON MAGNESIUM- AND POTASSIUM-NICOTINYL-ASPARAGINATE (MG + K - NA)].
Topics: Asparagine; Biomedical Research; Drug Therapy; Electrolytes; Fatigue; Magnesium; Neoplasms; Pharmacology; Potassium; Rats; Research; Toxicology | 1964 |
[Experimental principles and clinical use of electrolyte carrier compounds. 4. The normalizing effect of potassium and magnesium asparaginate on an atypical substrate balance appearing in cancer patients. The importance of the problem for the host organis
Topics: Asparagine; Electrolytes; Humans; Magnesium; Neoplasms; Potassium | 1961 |
Crystal structure of trimestatin, a disintegrin containing a cell adhesion recognition motif RGD.
Topics: Amino Acid Motifs; Amino Acid Sequence; Angiogenesis Inhibitors; Antineoplastic Agents; Asparagine; Aspartic Acid; Blood Platelets; Cell Adhesion; Crystallography, X-Ray; Disintegrins; Integrin alphaVbeta3; Integrins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Neoplasms; Oligopeptides; Platelet Aggregation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Snake Venoms; Tryptophan | 2003 |
Optimization of a self antigen for presentation of multiple epitopes in cancer immunity.
Topics: Animals; Antigen Presentation; Asparagine; Autoantigens; CD8-Positive T-Lymphocytes; Epitopes; Female; Mice; Mice, Inbred C57BL; Models, Biological; Neoplasms; Oxidoreductases; T-Lymphocytes | 2006 |
Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies.
Topics: Adenomatous Polyposis Coli Protein; Animals; Asparagine; Disease Progression; Exodeoxyribonucleases; Flap Endonucleases; Genes, APC; Mice; Mice, Transgenic; Mutation; Neoplasms; Survival Rate | 2007 |
N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.
Topics: Animals; Asparagine; Cricetinae; Cricetulus; Dimerization; Humans; Mice; Models, Biological; Mutant Proteins; Neoplasms; Polysaccharides; Protein Structure, Tertiary; Receptor, ErbB-3; Sequence Deletion | 2008 |
Differences in chemotherapeutic susceptibility of human T-, B-, and non-T-/non-B-lymphocytes in culture.
Topics: Asparaginase; Asparagine; B-Lymphocytes; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Lymphocytes; Neoplasms; T-Lymphocytes | 1980 |
Hemodialysis of amino acids: basic studies in vitro.
Topics: Amino Acids; Asparagine; Dialysis; Humans; In Vitro Techniques; Kidneys, Artificial; Molecular Weight; Neoplasms; Renal Dialysis; Time Factors; Ultrafiltration; Urea | 1981 |
Theoretical and practical considerations in the use of hemodialysis for the therapeutic removal of asparagine and other amino acids.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Dose-Response Relationship, Drug; Female; Humans; Kidneys, Artificial; Lactate dehydrogenase-elevating virus; Mice; Microchemistry; Neoplasms; Renal Dialysis | 1981 |
Medicinal protection with Chinese herb-compound against radiation damage.
Topics: Animals; Asparagine; Drugs, Chinese Herbal; Glucosides; Hemostatics; Humans; Incidence; Leukopenia; Mice; Neoplasms; Phenylpropionates; Radiation Injuries, Experimental; Radiotherapy; Sitosterols | 1990 |
Asparagine-linked oligosaccharides in malignant tumour growth.
Topics: Animals; Asparagine; Cell Adhesion; Cell Division; Cell Line; Extracellular Matrix; Humans; Neoplasm Metastasis; Neoplasms; Oligosaccharides; Tumor Cells, Cultured | 1989 |
Immunosuppressive enzymes.
Topics: Animals; Antigens; Asparaginase; Asparagine; Encephalomyelitis, Autoimmune, Experimental; Erythrocytes; Glutamine; Graft vs Host Reaction; Hemocyanins; Hemolytic Plaque Technique; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Mice; Mitogens; Neoplasms; Sheep; Skin Tests; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous | 1973 |
Pharmacologic studies in man with crystallized L-asparaginase (NSC-109229).
Topics: Amidohydrolases; Asparaginase; Asparagine; Crystallization; Escherichia coli; Humans; Hydrolysis; Kinetics; Neoplasms; Time Factors | 1972 |
[Urinary excretion of asparagne and aspartate in control subjects and patients with cancer before and after treatment with K-Mg-aspartate].
Topics: Adolescent; Adult; Aged; Asparagine; Aspartic Acid; Breast Neoplasms; Cholecystitis; Female; Humans; Magnesium; Male; Middle Aged; Neoplasms; Potassium; Stomach Neoplasms | 1972 |
[Molecular and cellular bases of cytostatic therapy].
Topics: Antibiotics, Antineoplastic; Antimetabolites; Asparaginase; Asparagine; Cell Division; Cell Line; Cells; DNA; DNA, Neoplasm; Humans; Methotrexate; Neoplasms; Nitrogen; Protein Biosynthesis; RNA; RNA, Neoplasm | 1974 |
Biochemical and pharmacological studies with asparaginase in man.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Colonic Neoplasms; Escherichia coli; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Melanoma; Metabolic Clearance Rate; Middle Aged; Multiple Myeloma; Neoplasms; Neuroblastoma; Osteosarcoma | 1970 |
[To what extent L-asparaginase affects the tumor cells? Press information of the Sektion Onkologie der Paul-Ehrlich-Gesellschaft für Chemotherapie].
Topics: Adult; Age Factors; Antineoplastic Agents; Asparaginase; Asparagine; Child; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Neoplasms | 1969 |
Immunosuppressive effects of L-asparaginase.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine | 1970 |
Diminished oxidation of 14C-UL-L-asparagine to 14CO2 in mice and humans with tumors: a possible means for assessing efficacy of therapy?
Topics: Animals; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Humans; Injections, Intravenous; Leukemia, Lymphoid; Male; Mice; Multiple Myeloma; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction | 1970 |
Treatment of lymphosarcoma in the dog with L-asparaginase.
Topics: Amidohydrolases; Animals; Asparagine; Dogs; Escherichia coli; Guinea Pigs; Lymphoma, Non-Hodgkin; Mice; Neoplasms; Ouabain | 1967 |
Sensitivity to L-asparaginase and amino acid metabolism.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; Culture Techniques; Female; Formates; Glutamine; Half-Life; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Neoplasms; Rats; Spleen; Thymidine; Time Factors; Tritium | 1970 |
Amino acid levels following L-asparagine amidohydrolase (EC.3.5.1.1) therapy.
Topics: Amidohydrolases; Amino Acids; Asparaginase; Asparagine; Female; Glutamates; Glutamine; Humans; Male; Neoplasms | 1969 |
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions].
Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Electrophoresis; Elements; Glutamates; Histidine; Humans; Metabolic Diseases; Methionine; Neoplasms; Quaternary Ammonium Compounds | 1966 |