asparagine and Neoplasms

asparagine has been researched along with Neoplasms in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (47.83)	18.7374
1990's	2 (2.90)	18.2507
2000's	11 (15.94)	29.6817
2010's	16 (23.19)	24.3611
2020's	7 (10.14)	2.80

Authors

Authors	Studies
Batra, S; Chen, C; Davé, U; Fan, J; Jiang, J; Kapur, R; Liu, Y; Misra, J; Seim, G; Srivastava, S; Staschke, KA; Wek, RC; Zhang, C; Zhang, J; Zhong, M; Zhou, J; Zhou, L	1
Hlozkova, K; Safrhansova, L; Starkova, J	1
Oda, K; Wlodawer, A	1
Adams, CM; Cassel, TA; Chen, X; Fan, TW; Gnanaprakasam, JNR; Higashi, RM; Kang, S; Kushwaha, B; Lane, AN; Li, Z; Liu, L; Scott, DA; Wang, R; Wang, T; Xin, G; Yang, J; Zhang, J	1
Cinar, B; Dolgner, T; Fehlhaber, B; Forster, M; Hinze, L; Ibrahim, NK; Loxha, L; Niessen, J; Schreek, S; Stanulla, M; Stasche, AS	1
Chang, JH; Mou, CY; Mou, KY	1
Jiao, S; Wang, J; Wang, M; Wang, R; Wang, S; Zhang, J; Zhang, M	1
Harada, Y; Kizuka, Y; Ohkawa, Y; Taniguchi, N	1
Christofk, HR; Halbrook, CJ; Knott, SRV; Krall, AS; Lyssiotis, CA; Mittelman, SD; Momcilovic, M; Mullen, PJ; Schmid, EW; Shackelford, DB; Surjono, F; Thambundit, A	1
Bailly, C; Vergoten, G	1
Eoh, H; Gao, SJ; Jung, JU; Lee, JJ; Li, T; Lu, C; Ramos da Silva, S; Zhu, Y	1
Ho, M; Lemichez, E; Mettouchi, A; Wilson, BA	1
Bitencourt-Ferreira, G; de Azevedo, WF; Souto, AA; Volkart, PA	1
Hay, N; Terry, AR	1
Ann, J; Apfel, V; Barretina, J; Clish, CB; Deik, A; Galli, GG; Garraway, LA; Ghandi, M; Giannakis, M; Gopal, S; Hahn, WC; Hernandez, D; Keskula, P; Kryukov, GV; Li, H; Ning, S; Pagliarini, RA; Pierce, K; Root, DE; Schreiber, SL; Sellers, WR; Shkoza, D; Souza, A; Tsherniak, A; Vazquez, F; Zou, Y	1
Balasubramanian, MN; Butterworth, EA; Kilberg, MS	1
Chen, CY; Chen, HY; Chen, KB; Chen, KC	1
Chen, CY; Chen, HY; Chen, KC; Lee, WY	1
Cooper, AJ; Denton, TT; Deryabina, YI; Dorai, T; Isakova, EP; Krasnikov, BF; Pinto, JT; Shurubor, YI	1
Kim, HD; Kim, J; Kim, Y; Lee, MS	1
Fellinger, K; Gires, O; Hofmann, T; Munz, M; Schmitt, B	1
Bogyo, M; Lee, J	1
ERRERA, M; GREENSTEIN, JP	1
Bussolati, O; Chiarelli, LR; Covini, D; Digilio, R; Pasquetto, MV; Scotti, C; Tardito, S; Valentini, G	1
Li, C; Thompson, CB	1
Ando, M; Hanioka, N; Jinno, H; Kaniwa, N; Minami, H; Ohtsu, A; Ozawa, S; Saeki, M; Sai, K; Saijo, N; Saito, Y; Sawada, J; Shirao, K; Tanaka-Kagawa, T; Yoshida, T	1
MCCOY, TA; NEUMAN, RE	1
MCCOY, TA; ORR, GR; PATTERSON, MK	1
CHRISTENSEN, HN	1
LORINCZ, AB; RYAN, WL	1
SCHINDLER, R	2
MASHBURN, LT; WRISTON, JC	1
CONWAY, E; MCCOY, TA; PATTERSON, MK; WHITTLE, W	1
KOEHLER, L; NIEPER, HA	1
NIEPER, HA	1
Fujii, Y; Fujimoto, Z; Horii, K; Mizuno, H; Morita, T; Okuda, D	1
Friedman, M	1
Gobel, BH	1
Cohen, AD; Duan, F; Engelhorn, ME; Guevara-Patiño, JA; Houghton, AN; Liu, C; Merghoub, T; Rizzuto, G; Turk, MJ; Wolchok, JD	1
Bronson, R; Edelmann, W; Fan, K; Kucherlapati, M; Kucherlapati, R; Kuraguchi, M; Lipkin, M; Nguyen, A; Wei, K; Yang, K	1
Asahi, M; Lee, SH; Li, W; Miyoshi, E; Osumi, D; Takahashi, M; Taniguchi, N; Yokoe, S	1
Coleman, PS; Lavietes, BB	1
Berezov, TT	1
Arkin, H; Holland, JF; Ohnuma, T	1
Riley, V	1
Riley, V; Spackman, DH	1
Buckhaults, P; Chen, L; Fregien, N; Pierce, M	1
Dorr, RT; Fanta, P; Hersh, EM; Salmon, SE; Taylor, CW	1
Doi, H; Komatsu, H; Nishihira, T; Satomi, S	1
Borella, LD; Camitta, BM; Holcenberg, JS; Ring, BJ	1
Qian, JK; Wang, BZ; Wen, XL; Yang, GH; Zhang, RJ	1
Dennis, JW; Laferté, S; Vanderelst, I	1
Hersh, EM	1
Canellos, GP; Cooney, DA; Hardesty, CT; Haskell, CM	1
Daill, M; Fink, E; Kronberger, L; Schindler, R	1
Oettgen, HF	1
Cooney, DA; Handschumacher, RE	1
Hayaishi, O; Honjo, T	1
Jacobasch, KH	1
Freeman, A; Holland, JF; Ohnuma, T; Sinks, LF	1
Hersh, EM; Ohno, R	1
Chaudhuri, TK; Winchell, HS	1
Boyse, EA; Brodey, RS; Campbell, HA; Fidler, J; Old, LJ; Teller, JD	1
Balis, ME; Krakoff, IH; Miller, HK; Salser, JS	1
Balis, ME; Miller, HK; Salser, JS	1
Menkès, G	1

Reviews

19 review(s) available for asparagine and Neoplasms

Article	Year
Targeting amino acid metabolism in cancer. International review of cell and molecular biology, 2022, Volume: 373 Topics: Amino Acids; Arginine; Asparagine; Cysteine; Humans; Methionine; Neoplasms	2022
Overview of the Properties of Glutamic Peptidases That Are Present in Plant and Bacterial Pathogens and Play a Role in Celiac Disease and Cancer. Biochemistry, 2023, 02-07, Volume: 62, Issue:3 Topics: Asparagine; Bacteria; Celiac Disease; Glutamic Acid; Histidine; Humans; Neoplasms; Peptide Hydrolases	2023
Oligosaccharyltransferase: A Gatekeeper of Health and Tumor Progression. International journal of molecular sciences, 2019, Dec-02, Volume: 20, Issue:23 Topics: Amino Acid Sequence; Asparagine; Disease Progression; Drug Resistance, Neoplasm; Endoplasmic Reticulum; Glycosylation; Hexosyltransferases; Humans; Membrane Proteins; Neoplasms; Polysaccharides; Protein Processing, Post-Translational	2019
CNF1-like deamidase domains: common Lego bricks among cancer-promoting immunomodulatory bacterial virulence factors. Pathogens and disease, 2018, 07-01, Volume: 76, Issue:5 Topics: Amidohydrolases; Asparagine; Bacterial Toxins; Computational Biology; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli Proteins; Glutamine; Immunologic Factors; Neoplasms; rac1 GTP-Binding Protein; Virulence Factors	2018
Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review. Current drug targets, 2019, Volume: 20, Issue:7 Topics: Asparagine; Binding Sites; Cellular Senescence; Crystallography, X-Ray; Cyclin-Dependent Kinase 2; Drug Design; Humans; Leucine; Models, Molecular; Neoplasms; Protein Kinase Inhibitors	2019
Fuelling cancer cells. Nature reviews. Endocrinology, 2019, Volume: 15, Issue:2 Topics: Asparagine; Aspartic Acid; Disease Progression; Female; Humans; Lactic Acid; Male; Neoplasms; Oxygen Consumption; Proteins; Reference Values; Tumor Cells, Cultured; Tumor Microenvironment	2019
Asparagine synthetase: regulation by cell stress and involvement in tumor biology. American journal of physiology. Endocrinology and metabolism, 2013, Apr-15, Volume: 304, Issue:8 Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Stress, Physiological; Unfolded Protein Response	2013
ω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases. Amino acids, 2016, Volume: 48, Issue:1 Topics: Amidohydrolases; Animals; Asparagine; Glutamine; Humans; Hyperammonemia; Neoplasms; Nitrogen; Sulfur	2016
Expanding targets for a metabolic therapy of cancer: L-asparaginase. Recent patents on anti-cancer drug discovery, 2012, Volume: 7, Issue:1 Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Drug Delivery Systems; Glutaminase; Glutamine; Humans; Metabolic Networks and Pathways; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2012
Chemistry, biochemistry, and safety of acrylamide. A review. Journal of agricultural and food chemistry, 2003, Jul-30, Volume: 51, Issue:16 Topics: Acrylamide; Acrylic Resins; Alkylation; Animals; Asparagine; Environmental Exposure; Food Analysis; Food Handling; Humans; Maillard Reaction; Neoplasms; Nervous System; Reproduction; Risk Factors	2003
Chemotherapy-induced hypersensitivity reactions. Oncology nursing forum, 2005, Sep-01, Volume: 32, Issue:5 Topics: Antineoplastic Agents; Asparagine; Drug Hypersensitivity; Humans; Neoplasms; Oncology Nursing; Platinum Compounds; Podophyllotoxin; Risk Assessment; Risk Factors; Taxoids	2005
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia. CRC critical reviews in biochemistry, 1981, Volume: 11, Issue:4 Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cholesterol; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Glucose; Glutamates; Glutamic Acid; Glutamine; Lipid Bilayers; Liver Neoplasms, Experimental; Membrane Lipids; Mitochondria; Mitochondria, Liver; Models, Biological; Neoplasms; Oxygen Consumption; Phenotype; Purines; Pyrimidines; Pyruvates; Pyruvic Acid; Surface Properties	1981
[Asparagine biosynthesis and tumor growth]. Vestnik Akademii meditsinskikh nauk SSSR, 1982, Issue:3 Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases	1982
Regulation of N-acetylglucosaminyltransferase V and Asn-linked oligosaccharide beta(1,6) branching by a growth factor signaling pathway and effects on cell adhesion and metastatic potential. Glycoconjugate journal, 1997, Volume: 14, Issue:5 Topics: Animals; Asparagine; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Gene Expression Regulation, Enzymologic; Humans; N-Acetylglucosaminyltransferases; Neoplasm Metastasis; Neoplasms; Oligosaccharides; Signal Transduction	1997
[Anti-cancer therapy with amino acid imbalance]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 5 Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine	2001
[L-asparaginase: A new principle in the chemotherapy of malignant neoplasms]. Blut, 1969, Volume: 19, Issue:6 Topics: Animals; Antibodies; Asparaginase; Asparagine; Bone Marrow; Escherichia coli; Guinea Pigs; Humans; Leukemia, Lymphoid; Mice; Neoplasms; Serratia marcescens	1969
L-asparaginase and L-asparagine metabolism. Annual review of pharmacology, 1970, Volume: 10 Topics: Animals; Asparaginase; Asparagine; Chemical Phenomena; Chemistry; Dogs; Guinea Pigs; Humans; Mice; Neoplasms; Rats	1970
[Nutritional requirement of cancer cells: inhibition of the growth of cancer cells by L-asparaginase]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1970, Volume: 15, Issue:5 Topics: Animals; Asparaginase; Asparagine; Escherichia coli; Guinea Pigs; Humans; Leukemia; Mutation; Neoplasms; Neoplasms, Experimental	1970
[Enzyme therapy of malignant tumors]. Archiv fur Geschwulstforschung, 1969, Volume: 34, Issue:4 Topics: Animals; Asparaginase; Asparagine; Glutaminase; Guinea Pigs; Humans; Leukemia; Mice; Neoplasms; Neoplasms, Experimental; Rabbits; Rats	1969

Trials

2 trial(s) available for asparagine and Neoplasms

Article	Year
A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors. Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:1 Topics: Adult; Antineoplastic Agents; Asparaginase; Asparagine; Carcinoma, Non-Small-Cell Lung; Drug Screening Assays, Antitumor; Glutaminase; Humans; Lung Neoplasms; Melanoma; Neoplasm Proteins; Neoplasms; Polyethylene Glycols; Skin Neoplasms	2001
Phase I study of succinylated acinetobacter L-glutaminase-L-asparaginase. Cancer treatment reports, 1979, Volume: 63, Issue:6 Topics: Acinetobacter; Adolescent; Alkalosis, Respiratory; Amidohydrolases; Asparagine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Female; Glutamine; Humans; Hyperglycemia; Leukemia, Lymphoid; Male; Neoplasms	1979

Article

Year

A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors.

Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:1

Topics: Adult; Antineoplastic Agents; Asparaginase; Asparagine; Carcinoma, Non-Small-Cell Lung; Drug Screening Assays, Antitumor; Glutaminase; Humans; Lung Neoplasms; Melanoma; Neoplasm Proteins; Neoplasms; Polyethylene Glycols; Skin Neoplasms

2001

Phase I study of succinylated acinetobacter L-glutaminase-L-asparaginase.

Cancer treatment reports, 1979, Volume: 63, Issue:6

Topics: Acinetobacter; Adolescent; Alkalosis, Respiratory; Amidohydrolases; Asparagine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Female; Glutamine; Humans; Hyperglycemia; Leukemia, Lymphoid; Male; Neoplasms

1979

Other Studies

48 other study(ies) available for asparagine and Neoplasms

Article	Year
Asparagine bioavailability regulates the translation of MYC oncogene. Oncogene, 2022, Volume: 41, Issue:44 Topics: 3' Untranslated Regions; Amino Acids; Animals; Asparagine; Biological Availability; Genes, myc; Mice; Neoplasms; Proto-Oncogene Proteins c-myc	2022
Asparagine restriction enhances CD8 Nature metabolism, 2023, Volume: 5, Issue:8 Topics: Animals; Asparagine; CD8-Positive T-Lymphocytes; Glucose; Neoplasms; NF-E2-Related Factor 2	2023
GSK3α Regulates Temporally Dynamic Changes in Ribosomal Proteins upon Amino Acid Starvation in Cancer Cells. International journal of molecular sciences, 2023, Aug-26, Volume: 24, Issue:17 Topics: Amino Acids; Asparagine; Glycogen Synthase Kinase 3; Humans; Neoplasms; Protein Serine-Threonine Kinases; Ribosomal Proteins	2023
Sleeping Beauty Transposon-Mediated Asparaginase Gene Delivery by a Nanoparticle Platform. Scientific reports, 2019, 08-07, Volume: 9, Issue:1 Topics: A549 Cells; Antineoplastic Agents; Asparaginase; Asparagine; Cell Survival; Cisplatin; Combined Modality Therapy; DNA Transposable Elements; Doxorubicin; Drug Carriers; Gene Transfer Techniques; Genetic Therapy; Humans; Nanoparticles; Neoplasms; Plasmids; Silicon Dioxide; Transfection; Transposases	2019
Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation. Communications biology, 2019, Volume: 2 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibody Affinity; Antigen-Antibody Complex; Antineoplastic Agents, Immunological; Asparagine; B7-H1 Antigen; Binding, Competitive; Crystallography, X-Ray; Epitopes; Female; Glycosylation; Humans; Mice; Mice, Inbred C57BL; Models, Molecular; Neoplasms; Nivolumab; Programmed Cell Death 1 Ligand 2 Protein; Programmed Cell Death 1 Receptor; Protein Interaction Domains and Motifs	2019
Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth. Cell metabolism, 2021, 05-04, Volume: 33, Issue:5 Topics: Activating Transcription Factor 4; Animals; Asparagine; Aspartic Acid; Cell Line, Tumor; Cell Proliferation; Diet; Electron Transport Chain Complex Proteins; Humans; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Mice, Inbred NOD; Mitochondria; Neoplasms; Nucleotides; Survival Rate	2021
Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach. Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:18 Topics: Asparagine; Child; Chloroquine; Fatty Acids; Humans; Hydroxychloroquine; Membrane Proteins; Neoplasms; Neuronal Ceroid-Lipofuscinoses; Palmitates; Thiolester Hydrolases	2022
A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus. mBio, 2017, 08-15, Volume: 8, Issue:4 Topics: Asparagine; Aspartate Aminotransferases; Aspartic Acid; Cell Proliferation; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Herpesvirus 8, Human; Humans; Metabolic Networks and Pathways; Neoplasms; Nitrogen; Nucleotides	2017
The landscape of cancer cell line metabolism. Nature medicine, 2019, Volume: 25, Issue:5 Topics: Animals; Asparaginase; Asparagine; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cell Line, Tumor; DNA Methylation; Female; Gene Knockdown Techniques; Humans; Kynurenine; Liver Neoplasms; Metabolome; Mice; Mice, Nude; Neoplasms; Stomach Neoplasms	2019
In silico investigation of potential pyruvate kinase M2 regulators from traditional Chinese medicine against cancers. BioMed research international, 2014, Volume: 2014 Topics: Asparagine; Binding Sites; Carrier Proteins; Chemistry, Pharmaceutical; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Hydrogen Bonding; Ligands; Lysine; Medicine, Chinese Traditional; Membrane Proteins; Mitosis; Molecular Dynamics Simulation; Neoplasms; Protein Conformation; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Tryptophan	2014
In silico investigation of potential TRAF6 inhibitor from traditional Chinese medicine against cancers. BioMed research international, 2014, Volume: 2014 Topics: Animals; Asparagine; Cattle; Crystallography, X-Ray; Diiodotyrosine; Humans; Hydrogen Bonding; Hypoxia-Inducible Factor 1, alpha Subunit; Ligands; Medicine, Chinese Traditional; Molecular Dynamics Simulation; Neoplasms; Neovascularization, Pathologic; Protein Binding; Protein Structure, Secondary; TNF Receptor-Associated Factor 6; Tryptophan	2014
Asparagine protects tumor cells from glutamine depletion-induced cell death. Cancer discovery, 2014, Volume: 4, Issue:11 Topics: Asparagine; Aspartate-Ammonia Ligase; Cell Death; Glutamine; Humans; Neoplasms; Transcription Factor CHOP	2014
Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated. Oncotarget, 2016, Dec-06, Volume: 7, Issue:49 Topics: Animals; Asparagine; Brefeldin A; Cell Line, Tumor; Cell Movement; Endoplasmic Reticulum; Glycosylation; Golgi Apparatus; Humans; Mice; Monensin; Neoplasm Invasiveness; Neoplasms; NIH 3T3 Cells; Point Mutation; Protein Processing, Post-Translational; Protein Transport; Ribosomal Proteins; Transfection; Tunicamycin	2016
Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM. Frontiers in bioscience : a journal and virtual library, 2008, May-01, Volume: 13 Topics: 3T3 Cells; Animals; Antigens, Neoplasm; Asparagine; Cell Adhesion Molecules; Cell Line; Epithelial Cell Adhesion Molecule; Glycoside Hydrolases; Glycosylation; Humans; Kidney; Mice; Mutation; Neoplasms	2008
Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain. ACS chemical biology, 2010, Feb-19, Volume: 5, Issue:2 Topics: Animals; Asparagine; Carbocyanines; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Epoxy Compounds; Fluorescent Dyes; Humans; Mice; Mice, Inbred Strains; Neoplasms; NIH 3T3 Cells; Spectroscopy, Near-Infrared; Xenograft Model Antitumor Assays	2010
Desamidation of glutamine and asparagine in normal and neoplastic hepatic tissues. Journal of the National Cancer Institute, 1947, Volume: 7, Issue:4 Topics: Amino Acids; Asparagine; Glutamine; Liver Neoplasms; Neoplasms	1947
Cancer. DNA damage, deamidation, and death. Science (New York, N.Y.), 2002, Nov-15, Volume: 298, Issue:5597 Topics: Antineoplastic Agents; Apoptosis; Asparagine; Aspartic Acid; bcl-X Protein; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA, Neoplasm; Genes, p53; Genes, Retinoblastoma; Humans; Models, Biological; Mutation; Neoplasms; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Retinoblastoma Protein; Tumor Suppressor Protein p53	2002
Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2 Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Camptothecin; COS Cells; Exons; Genetic Variation; Glucuronates; Glucuronic Acid; Glucuronosyltransferase; Humans; Irinotecan; Japan; Mutation; Neoplasms; Polymorphism, Single Nucleotide; Transfection; UDP-Glucuronosyltransferase 1A9	2003
Dual requirement of Walker carcinosarcoma 256 in vitro for asparagine and glutamine. Science (New York, N.Y.), 1956, Jul-20, Volume: 124, Issue:3212 Topics: Animals; Asparagine; Biochemical Phenomena; Carcinoma 256, Walker; Glutamine; Humans; In Vitro Techniques; Neoplasms	1956
ASPARAGINE-C14 AND GLUTAMINE-C14 FROM ANIMAL CELL PROTEIN AND THEIR CHEMICAL DEGRADATION. Analytical biochemistry, 1963, Volume: 6 Topics: Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Glutamine; Ion Exchange Resins; Malates; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Proteins; Research; Sarcoma; Sarcoma, Experimental	1963
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS. Proceedings of the National Academy of Sciences of the United States of America, 1964, Volume: 51 Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research	1964
FREE AMINO ACIDS OF HUMAN BREAST CANCER. The Nebraska state medical journal, 1964, Volume: 49 Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine	1964
QUANTITATIVE COLONIAL GROWTH OF MAMMALIAN CELLS IN FIBRIN CELLS. Experimental cell research, 1964, Volume: 34 Topics: Asparagine; Fibrin; Folic Acid; Immune Sera; Mast Cells; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Serine; Thrombin; Tissue Culture Techniques	1964
TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI. Archives of biochemistry and biophysics, 1964, Volume: 105 Topics: Amidohydrolases; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Bacillus; Electrophoresis; Escherichia coli; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Experimental	1964
IN VITRO EFFECTS OF GUINEA PIG SERUM ON THE JENSEN, JA-1 AND JA-2 SARCOMAS. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119 Topics: Amidohydrolases; Animals; Asparagine; Blood; Culture Media; Guinea Pigs; In Vitro Techniques; Metabolism; Neoplasms; Pharmacology; Research; Research Design; Sarcoma; Sarcoma, Experimental; Tissue Culture Techniques	1965
[EXPERIMENTAL STUDIES AND CLINICAL USE OF ELECTROLYTE-CARRIER COMPOUNDS. 6. ORIENTATIONAL RESEARCH ON MAGNESIUM- AND POTASSIUM-NICOTINYL-ASPARAGINATE (MG + K - NA)]. Arztliche Forschung, 1964, Nov-10, Volume: 18 Topics: Asparagine; Biomedical Research; Drug Therapy; Electrolytes; Fatigue; Magnesium; Neoplasms; Pharmacology; Potassium; Rats; Research; Toxicology	1964
[Experimental principles and clinical use of electrolyte carrier compounds. 4. The normalizing effect of potassium and magnesium asparaginate on an atypical substrate balance appearing in cancer patients. The importance of the problem for the host organis Arztliche Forschung, 1961, Nov-10, Volume: 15 Topics: Asparagine; Electrolytes; Humans; Magnesium; Neoplasms; Potassium	1961
Crystal structure of trimestatin, a disintegrin containing a cell adhesion recognition motif RGD. Journal of molecular biology, 2003, Oct-03, Volume: 332, Issue:5 Topics: Amino Acid Motifs; Amino Acid Sequence; Angiogenesis Inhibitors; Antineoplastic Agents; Asparagine; Aspartic Acid; Blood Platelets; Cell Adhesion; Crystallography, X-Ray; Disintegrins; Integrin alphaVbeta3; Integrins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Neoplasms; Oligopeptides; Platelet Aggregation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Snake Venoms; Tryptophan	2003
Optimization of a self antigen for presentation of multiple epitopes in cancer immunity. The Journal of clinical investigation, 2006, Volume: 116, Issue:5 Topics: Animals; Antigen Presentation; Asparagine; Autoantigens; CD8-Positive T-Lymphocytes; Epitopes; Female; Mice; Mice, Inbred C57BL; Models, Biological; Neoplasms; Oxidoreductases; T-Lymphocytes	2006
Tumor progression in Apc(1638N) mice with Exo1 and Fen1 deficiencies. Oncogene, 2007, Sep-20, Volume: 26, Issue:43 Topics: Adenomatous Polyposis Coli Protein; Animals; Asparagine; Disease Progression; Exodeoxyribonucleases; Flap Endonucleases; Genes, APC; Mice; Mice, Transgenic; Mutation; Neoplasms; Survival Rate	2007
N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion. Biochimica et biophysica acta, 2008, Volume: 1780, Issue:3 Topics: Animals; Asparagine; Cricetinae; Cricetulus; Dimerization; Humans; Mice; Models, Biological; Mutant Proteins; Neoplasms; Polysaccharides; Protein Structure, Tertiary; Receptor, ErbB-3; Sequence Deletion	2008
Differences in chemotherapeutic susceptibility of human T-, B-, and non-T-/non-B-lymphocytes in culture. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 75 Topics: Asparaginase; Asparagine; B-Lymphocytes; Cell Line; Cytarabine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Lymphocytes; Neoplasms; T-Lymphocytes	1980
Hemodialysis of amino acids: basic studies in vitro. Nutrition and cancer, 1981, Volume: 2, Issue:3 Topics: Amino Acids; Asparagine; Dialysis; Humans; In Vitro Techniques; Kidneys, Artificial; Molecular Weight; Neoplasms; Renal Dialysis; Time Factors; Ultrafiltration; Urea	1981
Theoretical and practical considerations in the use of hemodialysis for the therapeutic removal of asparagine and other amino acids. Nutrition and cancer, 1981, Volume: 2, Issue:3 Topics: Amino Acids; Animals; Asparaginase; Asparagine; Dose-Response Relationship, Drug; Female; Humans; Kidneys, Artificial; Lactate dehydrogenase-elevating virus; Mice; Microchemistry; Neoplasms; Renal Dialysis	1981
Medicinal protection with Chinese herb-compound against radiation damage. Aviation, space, and environmental medicine, 1990, Volume: 61, Issue:8 Topics: Animals; Asparagine; Drugs, Chinese Herbal; Glucosides; Hemostatics; Humans; Incidence; Leukopenia; Mice; Neoplasms; Phenylpropionates; Radiation Injuries, Experimental; Radiotherapy; Sitosterols	1990
Asparagine-linked oligosaccharides in malignant tumour growth. Biochemical Society transactions, 1989, Volume: 17, Issue:1 Topics: Animals; Asparagine; Cell Adhesion; Cell Division; Cell Line; Extracellular Matrix; Humans; Neoplasm Metastasis; Neoplasms; Oligosaccharides; Tumor Cells, Cultured	1989
Immunosuppressive enzymes. Transplantation proceedings, 1973, Volume: 5, Issue:3 Topics: Animals; Antigens; Asparaginase; Asparagine; Encephalomyelitis, Autoimmune, Experimental; Erythrocytes; Glutamine; Graft vs Host Reaction; Hemocyanins; Hemolytic Plaque Technique; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Mice; Mitogens; Neoplasms; Sheep; Skin Tests; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous	1973
Pharmacologic studies in man with crystallized L-asparaginase (NSC-109229). Cancer chemotherapy reports, 1972, Volume: 56, Issue:5 Topics: Amidohydrolases; Asparaginase; Asparagine; Crystallization; Escherichia coli; Humans; Hydrolysis; Kinetics; Neoplasms; Time Factors	1972
[Urinary excretion of asparagne and aspartate in control subjects and patients with cancer before and after treatment with K-Mg-aspartate]. Wiener klinische Wochenschrift, 1972, Nov-10, Volume: 84, Issue:45 Topics: Adolescent; Adult; Aged; Asparagine; Aspartic Acid; Breast Neoplasms; Cholecystitis; Female; Humans; Magnesium; Male; Middle Aged; Neoplasms; Potassium; Stomach Neoplasms	1972
[Molecular and cellular bases of cytostatic therapy]. Schweizerische medizinische Wochenschrift, 1974, Feb-23, Volume: 104, Issue:8 Topics: Antibiotics, Antineoplastic; Antimetabolites; Asparaginase; Asparagine; Cell Division; Cell Line; Cells; DNA; DNA, Neoplasm; Humans; Methotrexate; Neoplasms; Nitrogen; Protein Biosynthesis; RNA; RNA, Neoplasm	1974
Biochemical and pharmacological studies with asparaginase in man. Cancer research, 1970, Volume: 30, Issue:9 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Colonic Neoplasms; Escherichia coli; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Melanoma; Metabolic Clearance Rate; Middle Aged; Multiple Myeloma; Neoplasms; Neuroblastoma; Osteosarcoma	1970
[To what extent L-asparaginase affects the tumor cells? Press information of the Sektion Onkologie der Paul-Ehrlich-Gesellschaft für Chemotherapie]. Munchener medizinische Wochenschrift (1950), 1969, Sep-12, Volume: 111, Issue:37 Topics: Adult; Age Factors; Antineoplastic Agents; Asparaginase; Asparagine; Child; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Neoplasms	1969
Immunosuppressive effects of L-asparaginase. Cancer research, 1970, Volume: 30, Issue:6 Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine	1970
Diminished oxidation of 14C-UL-L-asparagine to 14CO2 in mice and humans with tumors: a possible means for assessing efficacy of therapy? Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1970, Volume: 11, Issue:10 Topics: Animals; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Humans; Injections, Intravenous; Leukemia, Lymphoid; Male; Mice; Multiple Myeloma; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction	1970
Treatment of lymphosarcoma in the dog with L-asparaginase. Cancer, 1967, Volume: 20, Issue:7 Topics: Amidohydrolases; Animals; Asparagine; Dogs; Escherichia coli; Guinea Pigs; Lymphoma, Non-Hodgkin; Mice; Neoplasms; Ouabain	1967
Sensitivity to L-asparaginase and amino acid metabolism. Journal of the National Cancer Institute, 1970, Volume: 44, Issue:5 Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; Culture Techniques; Female; Formates; Glutamine; Half-Life; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Neoplasms; Rats; Spleen; Thymidine; Time Factors; Tritium	1970
Amino acid levels following L-asparagine amidohydrolase (EC.3.5.1.1) therapy. Cancer research, 1969, Volume: 29, Issue:1 Topics: Amidohydrolases; Amino Acids; Asparaginase; Asparagine; Female; Glutamates; Glutamine; Humans; Male; Neoplasms	1969
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions]. Journal of chromatography, 1966, Volume: 25, Issue:1 Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Electrophoresis; Elements; Glutamates; Histidine; Humans; Metabolic Diseases; Methionine; Neoplasms; Quaternary Ammonium Compounds	1966