asparagine and Lung Neoplasms

asparagine has been researched along with Lung Neoplasms in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.64)18.7374
1990's2 (9.09)18.2507
2000's5 (22.73)29.6817
2010's7 (31.82)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Bu, Y; Cai, DJ; Deng, YZ; Hu, CP; Li, L; Li, M; Sun, LQ; Zhang, ZY1
Hanada, K; Itatani, Y; Kawada, K; Maekawa, H; Miyoshi, H; Nishikawa, G; Obama, K; Taketo, MM1
Chen, H; Cui, J; Fan, L; Fu, Y; Han, K; Hu, H; Yin, S; Zhao, C; Zhao, S1
Dohmae, N; Hattori, A; Hirano, Y; Ikeda, H; Kakeya, H; Nishio, K; Pan, Y; Sakai, K; Suzuki, T1
Dong, Z; Jiang, P; Li, D; Li, G; Li, L; Wu, J1
Chang, CC; Chang, TH; Changou, CA; Chen, YF; Chen, YL; Cheng, TM; Chiang, WF; Chuang, KH; Lee, KH; Pan, SH; Shieh, DB; Tsui, WL; Tu, CC; Wu, MH; Wu, SY1
Carey, LA; D'Santos, CS; Dickopf, S; Erard, N; Fish, L; Gable, AL; Goodarzi, H; Hannon, GJ; Harrell, JC; Khan, S; Kim, SY; Knott, SRV; Maceli, AR; Papachristou, EK; Perou, CM; Poulogiannis, G; Soto, M; Turgeon, MO; Wagenblast, E; Wagner, M; Wilkinson, JE1
Chen, M; Guo, J; Liang, G; Shi, L; Tan, X; Wang, Y; Xian, L1
Cao, Z; Fan, J; Ju, D; Shen, W; Xu, Z; Yang, P; Zhang, B; Zhang, X1
Chen, ZN; Fu, ZG; Huang, W; Jiang, JL; Jing, L; Li, JH; Lin, P; Liu, ZY; Meng, Y; Shen, HM; Wu, B; Xu, BQ; Zhou, Y1
Boev, RS; Burkova, VN; Kuznetsova, TI; Urazova, LN1
Ahn, JB; Choi, SH; Friedman, M; Im, NK; Kim, HJ; Kozukue, N; Levin, CE1
Liang, G; Lin, DX; Lu, WF; Miao, XP; Qi, J; Tan, W; Wu, M; Xing, DY; Yu, CY; Zhou, CN1
Oliver, J; Palou, A; Proenza, AM; Roca, P1
LORINCZ, AB; RYAN, WL1
Bougioukas, G; Bouros, D; Gatter, KC; Giatromanolaki, A; Harris, AL; Koukourakis, MI; Pezzella, F; Sivridis, E; Turley, H1
Hageman, JJ; Koomen, GJ; Pandit, UK; Wanner, MJ1
Chen, HL; Guo, HB; Liu, F; Zhao, JH1
Dorr, RT; Fanta, P; Hersh, EM; Salmon, SE; Taylor, CW1
Avilés, M; Ballesta, J; Castells, MT; Madrid, JF; Martínez-Menárguez, JA1
Debray, H; Dus, D; Montreuil, J; Strecker, G; Wieruszeski, JM1
Canellos, GP; Cooney, DA; Hansen, HH; Haskell, CM1

Reviews

1 review(s) available for asparagine and Lung Neoplasms

ArticleYear
Polymorphism of ERCC2 Asp312Asn with lung cancer risk: evidence from 20,101 subjects.
    Genetic testing and molecular biomarkers, 2014, Volume: 18, Issue:1

    Topics: Asparagine; Aspartic Acid; Case-Control Studies; Humans; Lung Neoplasms; Polymorphism, Genetic; Xeroderma Pigmentosum Group D Protein

2014

Trials

1 trial(s) available for asparagine and Lung Neoplasms

ArticleYear
A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:1

    Topics: Adult; Antineoplastic Agents; Asparaginase; Asparagine; Carcinoma, Non-Small-Cell Lung; Drug Screening Assays, Antitumor; Glutaminase; Humans; Lung Neoplasms; Melanoma; Neoplasm Proteins; Neoplasms; Polyethylene Glycols; Skin Neoplasms

2001

Other Studies

20 other study(ies) available for asparagine and Lung Neoplasms

ArticleYear
Asparagine synthetase regulates lung-cancer metastasis by stabilizing the β-catenin complex and modulating mitochondrial response.
    Cell death & disease, 2022, 06-23, Volume: 13, Issue:6

    Topics: Asparagine; Aspartate-Ammonia Ligase; beta Catenin; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cell Line, Tumor; Humans; Lung; Lung Neoplasms

2022
Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells.
    Cells, 2022, 10-18, Volume: 11, Issue:20

    Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Proto-Oncogene Proteins p21(ras); RNA, Small Interfering; Spheroids, Cellular; Xenograft Model Antitumor Assays

2022
Methylseleninic acid overcomes gefitinib resistance through asparagine-MET-TOPK signaling axis in non-small cell lung cancer cells.
    Biochemical pharmacology, 2023, Volume: 215

    Topics: Antineoplastic Agents; Asparagine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Protein Kinase Inhibitors; Quinazolines

2023
Bisabosqual A: A novel asparagine synthetase inhibitor suppressing the proliferation and migration of human non-small cell lung cancer A549 cells.
    European journal of pharmacology, 2023, Dec-05, Volume: 960

    Topics: A549 Cells; Asparagine; Aspartate-Ammonia Ligase; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Phosphatidylinositol 3-Kinases

2023
Asparagine enhances LCK signalling to potentiate CD8
    Nature cell biology, 2021, Volume: 23, Issue:1

    Topics: Animals; Asparagine; CD8-Positive T-Lymphocytes; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Phosphorylation; Signal Transduction; src-Family Kinases; Tumor Cells, Cultured; Tyrosine

2021
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation.
    Oncogene, 2018, 01-04, Volume: 37, Issue:1

    Topics: Adult; Animals; Antigens, CD; Asparagine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; ErbB Receptors; Glycosylation; GPI-Linked Proteins; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Mouth Neoplasms; N-Acetylglucosaminyltransferases; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays

2018
Asparagine bioavailability governs metastasis in a model of breast cancer.
    Nature, 2018, 02-15, Volume: 554, Issue:7692

    Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Biological Availability; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Epithelial-Mesenchymal Transition; Female; Humans; Lung Neoplasms; Male; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Prostatic Neoplasms; Reproducibility of Results; RNA Interference

2018
Targeting asparagine and autophagy for pulmonary adenocarcinoma therapy.
    Applied microbiology and biotechnology, 2016, Volume: 100, Issue:21

    Topics: Adenocarcinoma; Apoptosis; Asparaginase; Asparagine; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Lung Neoplasms; Models, Biological; Reactive Oxygen Species

2016
N-linked glycosylation at Asn152 on CD147 affects protein folding and stability: promoting tumour metastasis in hepatocellular carcinoma.
    Scientific reports, 2016, 11-21, Volume: 6

    Topics: Animals; Asparagine; Basigin; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum-Associated Degradation; Gene Expression Regulation, Neoplastic; Glycosylation; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Polysaccharides; Protein Folding; Proteolysis

2016
Efficacy of natural L-asparagine in the complex therapy for malignant tumors in experimental studies.
    Experimental oncology, 2011, Volume: 33, Issue:2

    Topics: Animals; Arctium; Asparagine; Carcinoma, Lewis Lung; Cell Proliferation; Cyclophosphamide; Female; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Plant Roots; Tumor Cells, Cultured

2011
Changes in free amino acid, protein, and flavonoid content in jujube (Ziziphus jujube) fruit during eight stages of growth and antioxidative and cancer cell inhibitory effects by extracts.
    Journal of agricultural and food chemistry, 2012, Oct-17, Volume: 60, Issue:41

    Topics: Amino Acids; Antineoplastic Agents, Phytogenic; Antioxidants; Asparagine; Cell Line, Tumor; Dose-Response Relationship, Drug; Flavonoids; Fruit; HeLa Cells; Humans; Lung Neoplasms; Plant Extracts; Plant Proteins; U937 Cells; Ziziphus

2012
[Association of genetic polymorphisms in the DNA repair gene XPD with risk of lung and esophageal cancer in a Chinese population in Beijing].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2003, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Asparagine; Aspartic Acid; Carcinoma, Squamous Cell; China; DNA; DNA Helicases; DNA Repair; DNA-Binding Proteins; Esophageal Neoplasms; Female; Gene Frequency; Genotype; Humans; Logistic Models; Lung Neoplasms; Male; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proteins; Risk Factors; Smoking; Transcription Factors; Xeroderma Pigmentosum Group D Protein

2003
Breast and lung cancer are associated with a decrease in blood cell amino acid content.
    The Journal of nutritional biochemistry, 2003, Volume: 14, Issue:3

    Topics: Adult; Aged; Amino Acids; Amino Acids, Essential; Asparagine; Blood Cells; Breast Neoplasms; Female; Glutamic Acid; Humans; Lung Neoplasms; Male; Middle Aged; Ornithine; Plasma; Proline; Valine

2003
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway.
    Cancer letters, 2008, Apr-08, Volume: 262, Issue:1

    Topics: Asparagine; Carcinoma, Non-Small-Cell Lung; Humans; Hypoxia-Inducible Factor 1; Lung Neoplasms; Mixed Function Oxygenases; Procollagen-Proline Dioxygenase; Repressor Proteins; Transcriptional Activation

2008
Potential carcinostatics. 4. Synthesis and biological properties of erythro- and threo-beta-fluoroaspartic acid and erythro-beta-fluoroasparagine.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:1

    Topics: Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Female; Leukemia L5178; Lung Neoplasms; Male; Mice; Models, Molecular; Molecular Conformation; Neoplasms, Experimental

1980
Down-regulation of N-acetylglucosaminyltransferase V by tumorigenesis- or metastasis-suppressor gene and its relation to metastatic potential of human hepatocarcinoma cells.
    Journal of cellular biochemistry, 2000, Sep-07, Volume: 79, Issue:3

    Topics: Adenocarcinoma; Asparagine; Carbohydrate Conformation; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Collagen; Cyclin-Dependent Kinase Inhibitor p16; Drug Combinations; Enzyme Induction; Fibronectins; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, Tumor Suppressor; Glycoproteins; Humans; Laminin; Liver Neoplasms; Lung Neoplasms; Monomeric GTP-Binding Proteins; N-Acetylglucosaminyltransferases; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phenotype; Polysaccharides; Proteoglycans; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transcription Factors; Transfection; Tumor Cells, Cultured

2000
Ultrastructural localization of glycoconjugates in human bronchial glands: the subcellular organization of N- and O-linked oligosaccharide chains.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1992, Volume: 40, Issue:2

    Topics: Asparagine; Bronchi; Carbohydrate Sequence; Cytoplasmic Granules; Disaccharides; Glycoconjugates; Golgi Apparatus; Humans; Immunoenzyme Techniques; Lectins; Lung Neoplasms; Molecular Sequence Data; Mucous Membrane; Oligosaccharides

1992
Structures of the alpha(1-3)-galactose-containing asparagine-linked glycans of a Lewis lung carcinoma cell subline resistant to Aleuria aurantia agglutinin: elucidation by 1H-NMR spectroscopy.
    Glycoconjugate journal, 1991, Volume: 8, Issue:1

    Topics: Animals; Asparagine; Carbohydrate Conformation; Carbohydrate Sequence; Drug Resistance; Galactose; Glycopeptides; Lectins; Lung Neoplasms; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligosaccharides; Polysaccharides; Protons; Sugar Alcohols; Tumor Cells, Cultured

1991
Biocmical and pharmacologic effects of L-asparaginase in man.
    The Journal of laboratory and clinical medicine, 1970, Volume: 75, Issue:5

    Topics: Asparaginase; Asparagine; Carcinoma, Squamous Cell; Escherichia coli; Head; Head and Neck Neoplasms; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lung Neoplasms; Melanoma; Neoplasm Metastasis; Plasma; Skin Neoplasms; Time Factors

1970