asparagine and Liver Neoplasms

asparagine has been researched along with Liver Neoplasms in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199017 (53.13)18.7374
1990's5 (15.63)18.2507
2000's2 (6.25)29.6817
2010's6 (18.75)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Bai, J; Chang, J; Shi, J; Sun, C; Tang, R; Wang, H; Zhang, Q; Zhou, K1
Chen, L; Chen, Y; Guo, Y; Lei, Y; Li, L; Liu, H; Sha, F; Tian, X; Zhou, Q1
Gee, HY; Kang, J; Kim, I; Park, JW1
Ann, J; Apfel, V; Barretina, J; Clish, CB; Deik, A; Galli, GG; Garraway, LA; Ghandi, M; Giannakis, M; Gopal, S; Hahn, WC; Hernandez, D; Keskula, P; Kryukov, GV; Li, H; Ning, S; Pagliarini, RA; Pierce, K; Root, DE; Schreiber, SL; Sellers, WR; Shkoza, D; Souza, A; Tsherniak, A; Vazquez, F; Zou, Y1
Arcangeli, A; Armeanu-Ebinger, S; Armento, A; Barilli, A; Bianchi, MG; Bussolati, O; Campanini, N; Chiu, M; Dall'Asta, V; Fuchs, J; Missale, G; Pillozzi, S; Silini, EM; Tardito, S; Uggeri, J1
Cao, B; Chen, X; Cui, C; Jiang, J; Li, Y; Liu, C; Liu, Y; Lu, H; Ren, S; Wei, Y; Xie, L; Xing, Y; Yang, F1
Chen, ZN; Fu, ZG; Huang, W; Jiang, JL; Jing, L; Li, JH; Lin, P; Liu, ZY; Meng, Y; Shen, HM; Wu, B; Xu, BQ; Zhou, Y1
ERRERA, M; GREENSTEIN, JP1
Guo, Y; Li, YT; Liu, RM; Rao, FF; Si, MZ; Tang, WY; Xiong, Y; Zhang, JM1
LORINCZ, AB; RYAN, WL1
Cho, H; Choi, KO; Choi, SM; Park, H; Park, YK; Yang, EG1
Christensen, HN; Vadgama, JV1
Chen, HL; Dong, SC; Ju, TZ; Yang, XP1
Abramson, FP; Kusmierz, JJ1
Kato, S; Maeda, Y; Matsumoto, K; Yuki, H1
Hayashi, N; Hori, M; Miyoshi, E; Noda, K; Taniguchi, N; Uozumi, N1
Chen, HL; Guo, HB; Liu, F; Zhao, JH1
Brynes, S; Burckart, GJ; Mokotoff, M1
Bagaglio, JF; Mokotoff, M; Parikh, BS1
Bagaglio, JF; Brynes, S; Mokotoff, M1
Broze, GJ; Miletich, JP1
Fong, WF; Law, CL1
Bergenstal, R; Burg, A; Cooney, DA; Fleischman, R; Morrison, R; Yavelow, J; Zlotoff, R1
Cohen, L; Eagle, H; Levy, M; Washington, CL1
Orr, GR; Patterson, MK2
Baliga, BS; Borek, E; Srinivasan, PR; Weinstein, IB1
Abbondanza, A; Bonetti, E; Della Corte, E; Stirpe, F1
Knox, WE; Kupchik, HZ1
Grunberger, D; Morris, HP; Srinivasan, D; Srinivasan, PR; Weinstein, IB1
Chou, TC; Handschumacher, RE1
Hogan, BL; Murden, S1

Other Studies

32 other study(ies) available for asparagine and Liver Neoplasms

ArticleYear
An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma.
    BMC medical genomics, 2022, 10-25, Volume: 15, Issue:1

    Topics: Asparagine; Aspartate Aminotransferases; Biomarkers, Tumor; Carcinoma, Hepatocellular; Gene Expression Profiling; Glutamine; Humans; Liver Neoplasms; Prognosis; Tumor Microenvironment

2022
PTTG1 Reprograms Asparagine Metabolism to Promote Hepatocellular Carcinoma Progression.
    Cancer research, 2023, 07-14, Volume: 83, Issue:14

    Topics: Animals; Asparagine; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Hepatitis B virus; Liver Neoplasms; Mice; Prognosis; TOR Serine-Threonine Kinases

2023
A novel HIF1AN substrate KANK3 plays a tumor-suppressive role in hepatocellular carcinoma.
    Cell biology international, 2018, Volume: 42, Issue:3

    Topics: Amino Acid Sequence; Ankyrin Repeat; Asparagine; Carcinoma, Hepatocellular; Carrier Proteins; Cell Hypoxia; Cell Line, Tumor; Down-Regulation; Genes, Tumor Suppressor; HEK293 Cells; Hep G2 Cells; Humans; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Mixed Function Oxygenases; Oxygen; Repressor Proteins

2018
The landscape of cancer cell line metabolism.
    Nature medicine, 2019, Volume: 25, Issue:5

    Topics: Animals; Asparaginase; Asparagine; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cell Line, Tumor; DNA Methylation; Female; Gene Knockdown Techniques; Humans; Kynurenine; Liver Neoplasms; Metabolome; Mice; Mice, Nude; Neoplasms; Stomach Neoplasms

2019
Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts.
    British journal of cancer, 2014, Sep-09, Volume: 111, Issue:6

    Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; beta Catenin; Cadherins; Carcinoma, Hepatocellular; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamine; Hep G2 Cells; Humans; Ki-67 Antigen; Liver Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Nude; Mutation; Tumor Burden; Xenograft Model Antitumor Assays

2014
Mutation of N-linked glycosylation at Asn548 in CD133 decreases its ability to promote hepatoma cell growth.
    Oncotarget, 2015, Aug-21, Volume: 6, Issue:24

    Topics: AC133 Antigen; Amino Acid Sequence; Antigens, CD; Asparagine; Carcinoma, Hepatocellular; Cell Growth Processes; Glycoproteins; Glycosylation; Hep G2 Cells; Humans; Liver Neoplasms; Molecular Sequence Data; Mutation; Peptides

2015
N-linked glycosylation at Asn152 on CD147 affects protein folding and stability: promoting tumour metastasis in hepatocellular carcinoma.
    Scientific reports, 2016, 11-21, Volume: 6

    Topics: Animals; Asparagine; Basigin; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum-Associated Degradation; Gene Expression Regulation, Neoplastic; Glycosylation; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Polysaccharides; Protein Folding; Proteolysis

2016
Desamidation of glutamine and asparagine in normal and neoplastic hepatic tissues.
    Journal of the National Cancer Institute, 1947, Volume: 7, Issue:4

    Topics: Amino Acids; Asparagine; Glutamine; Liver Neoplasms; Neoplasms

1947
[Analysis of surface enhanced Raman scattering spectra of oxyhemoglobin for liver cancer with combined multivariate statistics].
    Guang pu xue yu guang pu fen xi = Guang pu, 2012, Volume: 32, Issue:9

    Topics: Algorithms; Asparagine; Discriminant Analysis; Humans; Liver Neoplasms; Oxyhemoglobins; Phenylalanine; Principal Component Analysis; Silver; Spectrum Analysis, Raman; Tyrosine

2012
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
Clioquinol, a Cu(II)/Zn(II) chelator, inhibits both ubiquitination and asparagine hydroxylation of hypoxia-inducible factor-1alpha, leading to expression of vascular endothelial growth factor and erythropoietin in normoxic cells.
    The Journal of biological chemistry, 2006, Nov-10, Volume: 281, Issue:45

    Topics: Asparagine; Carcinoma, Hepatocellular; Cell Hypoxia; Chelating Agents; Clioquinol; Copper; Cyclic AMP Response Element-Binding Protein; Erythropoietin; Humans; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Immunoprecipitation; Liver Neoplasms; Neuroblastoma; Oxygen; Peptide Fragments; Procollagen-Proline Dioxygenase; Protein Binding; Protein Processing, Post-Translational; Tumor Cells, Cultured; Ubiquitin; Vascular Endothelial Growth Factor A; Von Hippel-Lindau Tumor Suppressor Protein; Zinc

2006
Comparison of system N in fetal hepatocytes and in related cell lines.
    The Journal of biological chemistry, 1983, May-25, Volume: 258, Issue:10

    Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Line; Ethylmaleimide; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Lithium; Liver; Liver Neoplasms; Sodium

1983
Effect of retinoic acid on the structure of N-glycans on the surface of human hepatocarcinoma cells and its enzymatic mechanism.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:7

    Topics: Asparagine; Carbohydrate Sequence; Carcinoma, Hepatocellular; Chromatography, Affinity; Fucose; Fucosyltransferases; Humans; Liver Neoplasms; Membrane Glycoproteins; Molecular Sequence Data; Molecular Structure; N-Acetylglucosaminyltransferases; Polysaccharides; Tretinoin; Tritium; Tumor Cells, Cultured

1995
Tracing 15N with chemical reaction interface mass spectrometry: a demonstration using 15N-labeled glutamine and asparagine substrates in cell culture.
    Biological mass spectrometry, 1994, Volume: 23, Issue:12

    Topics: Asparagine; Carcinoma, Hepatocellular; Culture Media; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Liver Neoplasms; Nitrogen Isotopes; Tumor Cells, Cultured

1994
Alteration of asparagine-linked glycosylation in serum transferrin of patients with hepatocellular carcinoma.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Jan-14, Volume: 224, Issue:1

    Topics: Asparagine; Biomarkers, Tumor; Carbohydrate Sequence; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Glucose; Glycoproteins; Glycoside Hydrolases; Humans; Hydrolysis; Liver Cirrhosis; Liver Neoplasms; Molecular Sequence Data; Oligosaccharides; Transferrin

1994
Expression of alpha1-6 fucosyltransferase in rat tissues and human cancer cell lines.
    International journal of cancer, 1997, Sep-17, Volume: 72, Issue:6

    Topics: Animals; Asparagine; Biomarkers, Tumor; Brain; Carbohydrate Conformation; Carbohydrate Sequence; Carcinoma, Hepatocellular; Cloning, Molecular; Diagnosis, Differential; Fucosyltransferases; Gene Expression Regulation, Enzymologic; Humans; Liver Neoplasms; Male; Molecular Sequence Data; Neural Cell Adhesion Molecules; Oligosaccharides; Organ Specificity; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialic Acids; Stomach Neoplasms; Swine; Transcription, Genetic; Tumor Cells, Cultured

1997
Down-regulation of N-acetylglucosaminyltransferase V by tumorigenesis- or metastasis-suppressor gene and its relation to metastatic potential of human hepatocarcinoma cells.
    Journal of cellular biochemistry, 2000, Sep-07, Volume: 79, Issue:3

    Topics: Adenocarcinoma; Asparagine; Carbohydrate Conformation; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Collagen; Cyclin-Dependent Kinase Inhibitor p16; Drug Combinations; Enzyme Induction; Fibronectins; Gene Expression Regulation, Neoplastic; Genes, p16; Genes, Tumor Suppressor; Glycoproteins; Humans; Laminin; Liver Neoplasms; Lung Neoplasms; Monomeric GTP-Binding Proteins; N-Acetylglucosaminyltransferases; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phenotype; Polysaccharides; Proteoglycans; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transcription Factors; Transfection; Tumor Cells, Cultured

2000
Potential inhibitors of L-asparagine biosynthesis. 4. Substituted sulfonamide and sulfonylhydrazide analogues of L-asparagine.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:1

    Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Hydrazines; In Vitro Techniques; Leukemia, Experimental; Ligases; Liver Neoplasms; Mice; Neoplasms, Experimental; Rats; Structure-Activity Relationship; Sulfonamides

1978
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:4

    Topics: Animals; Asparagine; Aspartic Acid; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Hydroxy Acids; Ligases; Liver Neoplasms; Male; Molecular Conformation; Neoplasms, Experimental; Rats; Stereoisomerism; Structure-Activity Relationship

1975
Potential inhibitors of L-asparagine biosynthesis. 3. Aromatic sulfonyl fluoride analogs of L-asparagine and L-glutamine.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:9

    Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Liver Neoplasms; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Sulfones

1975
Beta protein C is not glycosylated at asparagine 329. The rate of translation may influence the frequency of usage at asparagine-X-cysteine sites.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Amino Acid Sequence; Antibodies; Asparagine; Binding Sites; Blotting, Western; Carcinoma, Hepatocellular; Cysteine; Epitopes; Glycoside Hydrolases; Glycosylation; Humans; Liver Neoplasms; Molecular Sequence Data; Oligosaccharides; Protein Biosynthesis; Protein C; Thrombin; Tumor Cells, Cultured; Warfarin

1990
The induction of ornithine decarboxylase by L-asparagine and intracellular alkalinization.
    Biochemistry international, 1988, Volume: 16, Issue:2

    Topics: Ammonium Chloride; Asparagine; Carcinoma, Hepatocellular; Enzyme Induction; Hydrogen-Ion Concentration; Intracellular Fluid; Liver Neoplasms; Ornithine Decarboxylase; Tumor Cells, Cultured

1988
Azotomycin--toxicologic, biochemical and pharmacologic studies in mice.
    Biochemical pharmacology, 1974, Dec-15, Volume: 23, Issue:24

    Topics: Animals; Antibiotics, Antineoplastic; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Ataxia; Azo Compounds; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Diarrhea; DNA; Formates; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutaminase; Lethal Dose 50; Ligases; Liver Neoplasms; Malate Dehydrogenase; Mice; Mice, Inbred Strains; Protein Biosynthesis; Seizures; Spleen; Time Factors

1974
The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize. II. Glutamic acid and glutamine; aspartic acid and asparagine.
    The Journal of biological chemistry, 1966, Nov-10, Volume: 241, Issue:21

    Topics: Animals; Asparagine; Aspartic Acid; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Culture Techniques; Glucose; Glutamates; Glutamine; Liver Neoplasms; Rats; Sarcoma, Experimental

1966
Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system.
    The Journal of biological chemistry, 1968, Jan-25, Volume: 243, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonium Chloride; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Carcinoma, Hepatocellular; Diphosphates; Female; Glutamine; Hydrogen-Ion Concentration; Hydroxamic Acids; Hydroxylamines; Liver Neoplasms; Magnesium; Manganese; Neoplasms, Experimental; Potassium; Rats

1968
Differences in the transfer RNA's of normal liver and Novikoff hepatoma.
    Proceedings of the National Academy of Sciences of the United States of America, 1969, Volume: 62, Issue:3

    Topics: Amino Acids; Animals; Asparagine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Ligases; Liver; Liver Neoplasms; Methods; Neoplasms, Experimental; Rats; RNA, Transfer; Tritium; Tyrosine

1969
The regulation of L-asparaginase activity in rats and mice. Effects of normal and malignant growth, of sex and of dietary changes.
    The Biochemical journal, 1969, Volume: 115, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Asparaginase; Asparagine; Carcinoma, Hepatocellular; Castration; Diet; Dietary Proteins; Estradiol; Female; Liver; Liver Neoplasms; Liver Regeneration; Male; Mice; Neoplasms, Experimental; Rats; Sex Factors; Starvation

1969
Assays of glutamine and its aminotransferase with the enol-borate of phenylpyruvate.
    Archives of biochemistry and biophysics, 1970, Volume: 136, Issue:1

    Topics: Age Factors; Animals; Asparagine; Boric Acids; Carcinoma, Hepatocellular; Cold Temperature; Drug Stability; Female; Fetus; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver Neoplasms; Liver Regeneration; Male; Mammary Neoplasms, Experimental; Mathematics; Methods; Neoplasms, Experimental; Organ Specificity; Phenylpyruvic Acids; Rats; Sex Factors; Solubility; Spectrophotometry; Time Factors; Transaminases; Ultraviolet Rays

1970
Alterations in specific transfer ribonucleic acids in a spectrum of hepatomas.
    Biochemistry, 1971, May-25, Volume: 10, Issue:11

    Topics: Animals; Asparagine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Diploidy; Escherichia coli; Genetic Code; Hindlimb; Histidine; Ligases; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Phenylalanine; Polynucleotides; Polyploidy; Rats; Ribosomes; RNA, Transfer; Tritium; Tyrosine; Ultracentrifugation

1971
Production of L-asparagine by tumor cells and the effect of asparagine analogs.
    Biochemical pharmacology, 1972, Volume: 21, Issue:1

    Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Azo Compounds; Bromine; Carbon Isotopes; Carcinoma, Hepatocellular; Chlorine; Glutamine; Kinetics; Leukemia, Experimental; Liver Neoplasms; Lymphoma, Non-Hodgkin; Mast Cells; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma 180

1972
Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply.
    Journal of cellular physiology, 1974, Volume: 83, Issue:3

    Topics: Amino Acids; Animals; Arginine; Asparagine; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Culture Media; Cycloheximide; Drug Synergism; Glutamine; Glycine; Immune Sera; Leucine; Liver Neoplasms; Neoplasm Proteins; Ornithine; Proline; Pyridoxal; Rats; Serine; Stimulation, Chemical; Time Factors

1974
Regeneration, tumor, dietary, and L-asparaginase effects on asparagine biosynthesis in rat liver.
    Cancer research, 1969, Volume: 29, Issue:6

    Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Escherichia coli; Female; Ligases; Liver; Liver Neoplasms; Liver Regeneration; Nutritional Requirements; Organ Size; Rats; Spleen

1969