asparagine and Leukemia

asparagine has been researched along with Leukemia in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (68.18)	18.7374
1990's	2 (4.55)	18.2507
2000's	5 (11.36)	29.6817
2010's	2 (4.55)	24.3611
2020's	5 (11.36)	2.80

Authors

Authors	Studies
Manonmani, HK; Sindhu, R	1
Bornhauser, B; Bourquin, JP; Cario, G; Chiosis, G; Cinar, B; Degar, J; Eckert, C; Fehlhaber, B; Gutierrez, A; Hinze, L; Ibrahim, NK; Loxha, L; McGuckin, C; Ponimaskin, E; Schreek, S; Stanulla, M; Zeug, A	1
Gladilina, YA; Shishparenok, AN; Zhdanov, DD	1
Abdel-Wahab, O; Allis, CD; Barrows, D; Baudrier, L; Birsoy, K; Cantor, J; Carey, B; Carroll, T; Garcia-Bermudez, J; Gates, LA; Guarecuco, R; Jeewajee, S; La, K; Malik, S; Molina, H; Passarelli, MC; Prizer, B; Roeder, RG; Williams, RT; Zhu, XG	1
Bonetta, R; Borowski, T; Fenech, AG; Hunter, GJ; Hunter, T; Kulp, M; Tabares, LC; Trinh, CH; Un, S	1
Inokuchi, N; Itagaki, T; Kobayashi, H; Motoyoshi, N; Suzuki, M	1
Kelo, E; Mononen, I; Noronkoski, T	1
Gu, LJ; He, YY; Jiang, H; Li, BS; Luo, CY	1
Langebrake, C; Reinhardt, D; Ritter, J	1
FISCHER, GA; HALEY, EE; WELCH, AD	1
MASHBURN, LT; WRISTON, JC	1
Broome, JD; Ding, Y; Li, Z	1
Kamen, BA	1
Anand, S; Kaur, G; Kumar, K; Verma, N	1
Berezov, TT	1
Bendich, A; Kafkewitz, D	1
Abeles, RH; Stern, AM; Tashjian, AH	1
Henderson, ES; Koishi, T; Minowada, J; Ohnuma, T	1
Broome, JD	1
Holcenberg, JS	1
Sugimura, K; Sukemori, S	1
Brinck, U; Ciesiolka, T; Gabius, HJ; Gabius, S; Lüsebrink, T	1
Cooney, DA; Milman, HA	1
Boisseau, M; Labatut, M; Moreau, F; Roulaud, F	1
Capizzi, RL; Papirmeister, B; Summers, WP	1
Boyse, EA; Campbell, HA; Old, LJ	1
Gallmeier, WM; Schmidt, CG	1
Bachynsky, N; Prager, MD	1
Bernard, J; Boiron, M; Jacquillat, C; Tanzer, J; Weil, M	1
Canellos, GP; Cooney, DA; Hansen, HH; Haskell, CM	1
Reizenstein, P	1
Hayaishi, O; Honjo, T	1
Jacobasch, KH	1
Freeman, A; Holland, JF; Ohnuma, T; Sinks, LF	1
Canellos, GP; Haskell, CM	2
Alexander, P	1
Banerjee, SP; Gallmeier, WM; Schmidt, CG	1
Bertino, JR; Capizzi, RL; Creasey, WA; Handschumacher, RE; Olayon, C; Peterson, RG; Skeel, RT; Zanes, R	1
Holland, JF; Onuma, T; Waligunda, J	1
Bernard, J; Boiron, M; Bussel, A; Dreyfus, B; Jacquillat, C; Larrieu, MJ; Loisel, JP; Rouesse, T; Weil, M	1
Balis, ME; Krakoff, IH; Miller, HK; Salser, JS	1
Nahum, LH	1

Reviews

8 review(s) available for asparagine and Leukemia

Article	Year
L-asparaginase-mediated Therapy in L-asparagine Auxotrophic Cancers: A Review. Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:13 Topics: Asparaginase; Asparagine; Child; Escherichia coli; Glutaminase; Glutamine; Humans; Leukemia	2022
Engineering and Expression Strategies for Optimization of L-Asparaginase Development and Production. International journal of molecular sciences, 2023, Oct-16, Volume: 24, Issue:20 Topics: Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Humans; Leukemia; Models, Biological	2023
Minimising the long-term adverse effects of childhood leukaemia therapy. Drug safety, 2002, Volume: 25, Issue:15 Topics: Alkylating Agents; Anthracyclines; Antimetabolites; Antineoplastic Agents; Asparaginase; Asparagine; Cardiovascular Diseases; Child; Clinical Trials as Topic; Glucocorticoids; Gonadal Disorders; Humans; Leukemia; Leukemia, Myeloid, Acute; Osteonecrosis; Podophyllotoxin; Polyethylene Glycols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tretinoin; Vinca Alkaloids	2002
[Asparagine biosynthesis and tumor growth]. Vestnik Akademii meditsinskikh nauk SSSR, 1982, Issue:3 Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases	1982
Enzyme-induced asparagine and glutamine depletion and immune system function. The American journal of clinical nutrition, 1983, Volume: 37, Issue:6 Topics: Ammonia; Animals; Asparaginase; Asparagine; Escherichia coli; Glutaminase; Glutamine; Humans; Immunosuppressive Agents; Leukemia; Lymphocytes; Polyethylene Glycols; Vibrio	1983
[Leukemia and nutrition--pathologic metabolism and distribution of protein, fat, folic acid, and iron]. Nordisk medicin, 1970, Jan-15, Volume: 83, Issue:3 Topics: Aged; Amino Acids; Asparagine; Fats; Folic Acid; Humans; Iron; Leukemia; Lymphoma; Middle Aged	1970
[Nutritional requirement of cancer cells: inhibition of the growth of cancer cells by L-asparaginase]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1970, Volume: 15, Issue:5 Topics: Animals; Asparaginase; Asparagine; Escherichia coli; Guinea Pigs; Humans; Leukemia; Mutation; Neoplasms; Neoplasms, Experimental	1970
[Enzyme therapy of malignant tumors]. Archiv fur Geschwulstforschung, 1969, Volume: 34, Issue:4 Topics: Animals; Asparaginase; Asparagine; Glutaminase; Guinea Pigs; Humans; Leukemia; Mice; Neoplasms; Neoplasms, Experimental; Rabbits; Rats	1969

Other Studies

36 other study(ies) available for asparagine and Leukemia

Article	Year
Supramolecular assembly of GSK3α as a cellular response to amino acid starvation. Molecular cell, 2022, 08-04, Volume: 82, Issue:15 Topics: Amino Acids; Asparaginase; Asparagine; Humans; Leukemia; Protein Serine-Threonine Kinases	2022
ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase. Cell metabolism, 2020, 04-07, Volume: 31, Issue:4 Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation; Humans; Leukemia; Mice, Inbred NOD; Mice, SCID; Repressor Proteins; Transcription, Genetic	2020
Substitution of histidine 30 by asparagine in manganese superoxide dismutase alters biophysical properties and supports proliferation in a K562 leukemia cell line. European biophysics journal : EBJ, 2021, Volume: 50, Issue:3-4 Topics: Animals; Asparagine; Binding Sites; Caenorhabditis elegans; Cell Proliferation; Crystallography, X-Ray; Histidine; Humans; K562 Cells; Leukemia; Protein Conformation; Superoxide Dismutase	2021
Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation. Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:2 Topics: Amino Acid Sequence; Amino Acid Substitution; Antineoplastic Agents; Asparagine; Aspartic Acid; Basidiomycota; Cell Proliferation; Glutamic Acid; Glutamine; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Leukemia; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Ribonucleases; Structure-Activity Relationship	2015
Depletion of L-asparagine supply and apoptosis of leukemia cells induced by human glycosylasparaginase. Leukemia, 2009, Volume: 23, Issue:6 Topics: Apoptosis; Asparagine; Aspartylglucosylaminase; Humans; Leukemia; Tumor Cells, Cultured	2009
[Relationship between the antileukemic activity of L-asparaginase and Asn level around leukemic cells]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2010, Volume: 12, Issue:7 Topics: Asparaginase; Asparagine; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Humans; Leukemia; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2010
The requirement for L-asparagine of mouse leukemia cells L5178Y in culture. Cancer research, 1961, Volume: 21 Topics: Animals; Asparagine; Leukemia; Leukemia, Experimental; Mice; Tissue Culture Techniques	1961
TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI. Archives of biochemistry and biophysics, 1964, Volume: 105 Topics: Amidohydrolases; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Bacillus; Electrophoresis; Escherichia coli; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Experimental	1964
Epigenetic changes in the repression and induction of asparagine synthetase in human leukemic cell lines. Leukemia, 2005, Volume: 19, Issue:3 Topics: Acetylation; Animals; Asparagine; Aspartate-Ammonia Ligase; Cell Division; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Coculture Techniques; Enzyme Induction; Epigenesis, Genetic; Gene Silencing; Histones; Humans; Leukemia; Macrophages; Methylation; Mice; Promoter Regions, Genetic	2005
L-asparaginase: old dog, more tricks and leukemia: not simply a liquid tumor. Journal of pediatric hematology/oncology, 2005, Volume: 27, Issue:5 Topics: Antineoplastic Agents; Asparagine; Humans; Leukemia	2005
E. coli K-12 asparaginase-based asparagine biosensor for leukemia. Artificial cells, blood substitutes, and immobilization biotechnology, 2007, Volume: 35, Issue:4 Topics: Alginates; Asparaginase; Asparagine; Biosensing Techniques; Collodion; Enzymes, Immobilized; Escherichia coli K12; Glucuronic Acid; Hexuronic Acids; Humans; Indicators and Reagents; Leukemia; Microspheres; Phenolsulfonphthalein; Silicon	2007
Antitumor activity of DL-threo-beta-fluoroasparagine against human leukemia cells in culture and L1210 cells in DBA mice. Cancer research, 1984, Volume: 44, Issue:12 Pt 1 Topics: Amino Acids; Animals; Antineoplastic Agents; Asparagine; Cell Division; Cell Line; Cell Survival; Drug Evaluation, Preclinical; Humans; Kinetics; Leukemia; Leukemia L1210; Mice; Structure-Activity Relationship	1984
Distinctive sensitivity of some T-leukemia cell lines to L-asparaginase. Gan, 1984, Volume: 75, Issue:3 Topics: Asparaginase; Asparagine; B-Lymphocytes; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Leukemia; Phenotype; T-Lymphocytes	1984
L-Asparaginase: discovery and development as a tumor-inhibitory agent. Cancer treatment reports, 1981, Volume: 65 Suppl 4 Topics: Animals; Asparaginase; Asparagine; Cell Line; Escherichia coli; Guinea Pigs; Half-Life; History, 20th Century; Humans; Leukemia; Lymphoma; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Sarcoma, Experimental	1981
Enzyme therapy of cancer, future studies. Cancer treatment reports, 1981, Volume: 65 Suppl 4 Topics: Adolescent; Amidohydrolases; Animals; Antineoplastic Agents; Arginine; Asparaginase; Asparagine; Child; Child, Preschool; Drug Evaluation; Drug Evaluation, Preclinical; Enzyme Therapy; Enzymes; Female; Glutaminase; Glutamine; Humans; Kinetics; Leukemia; Male; Mice	1981
Extracellular glutamine level reduction enhances 5-fluorouracil cytotoxicity. Cancer biochemistry biophysics, 1998, Volume: 16, Issue:1-2 Topics: Amino Acids; Animals; Asparagine; Cell Count; Dose-Response Relationship, Drug; Fluorouracil; Glutamine; Humans; Leukemia; Leukemia P388; Methotrexate; Mice; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured	1998
Glycopeptide-albumin derivative: it preparation and histochemical ligand properties. The Histochemical journal, 1991, Volume: 23, Issue:7 Topics: Asparagine; B-Lymphocytes; Binding Sites; Biotin; Breast Neoplasms; Cell Line; Concanavalin A; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Histocytochemistry; Humans; Leukemia; Mannose; Oligosaccharides; Pronase; Serum Albumin; Serum Albumin, Bovine; Staining and Labeling; Succinimides; T-Lymphocytes; Tumor Cells, Cultured	1991
Asparaginase and leukaemia. Lancet (London, England), 1968, May-18, Volume: 1, Issue:7551 Topics: Animals; Asparaginase; Asparagine; Escherichia coli; Guinea Pigs; Humans; Leukemia	1968
The distribution of L-asparagine synthetase in the principal organs of several mammalian and avian species. The Biochemical journal, 1974, Volume: 142, Issue:1 Topics: Amino Acids; Animals; Asparaginase; Asparagine; Autoanalysis; Brain; Carbon Radioisotopes; Cats; Cattle; Chickens; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Kidney; Leukemia; Ligases; Liver; Lung; Male; Mice; Neoplasms, Experimental; Ovary; Pancreas; Rabbits; Rats; Sheep; Spleen; Swine; Temperature; Testis; Turkeys	1974
[Urinary elimination of beta aminoisobutyric acid in malignant hemopathies]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1971, Volume: 165, Issue:1 Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aminoisobutyric Acids; Asparagine; Child; Female; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thymine; Vinblastine	1971
Use of the asparagine auxotroph of the L5178Y murine leukemia for the detection of chemical mutagens in vitro and in the host-mediated assay. Environmental health perspectives, 1973, Volume: 6 Topics: Acridines; Alkylating Agents; Animals; Asparagine; Aza Compounds; Cell Line; Cells, Cultured; Clone Cells; Culture Media; Genetic Techniques; Leukemia; Ligases; Male; Mesylates; Mice; Mice, Inbred Strains; Mutagens; Mutation; Nitrogen Mustard Compounds; Nitrosamines; Nitrosoguanidines	1973
L-asparagine and leukemia. Scientific American, 1968, Volume: 219, Issue:2 Topics: Animals; Asparaginase; Asparagine; Dogs; Escherichia coli; Guinea Pigs; Leukemia; Leukemia, Experimental; Mice; Neoplasm Transplantation	1968
[On the enzyme therapy of leukemias]. Deutsche medizinische Wochenschrift (1946), 1968, Nov-29, Volume: 93, Issue:48 Topics: Adolescent; Adult; Aged; Asparaginase; Asparagine; Blood Cell Count; Blood Sedimentation; Enzymes; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Follicular; Male; Plasmacytoma; Tritium; Uric Acid	1968
Asparagine synthetase in normal and malignant tissues: correlation with tumor sensitivity to asparaginase. Archives of biochemistry and biophysics, 1968, Sep-20, Volume: 127, Issue:1 Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Cell Nucleus; Enzyme Repression; Escherichia coli; Feedback; Glutamine; Guinea Pigs; Hydrogen-Ion Concentration; Kidney; Leukemia; Ligases; Liver; Lymphoid Tissue; Lymphoma; Lymphoma, Non-Hodgkin; Lysosomes; Mice; Microsomes; Mitochondria, Liver; Neoplasms, Experimental; Puromycin; Spleen; Stimulation, Chemical	1968
[Asparaginase]. La Presse medicale, 1968, Nov-16, Volume: 76, Issue:44 Topics: Asparaginase; Asparagine; Escherichia coli; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin	1968
Biocmical and pharmacologic effects of L-asparaginase in man. The Journal of laboratory and clinical medicine, 1970, Volume: 75, Issue:5 Topics: Asparaginase; Asparagine; Carcinoma, Squamous Cell; Escherichia coli; Head; Head and Neck Neoplasms; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lung Neoplasms; Melanoma; Neoplasm Metastasis; Plasma; Skin Neoplasms; Time Factors	1970
Biochemical and pharmacological studies with asparaginase in man. Cancer research, 1970, Volume: 30, Issue:9 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Child; Colonic Neoplasms; Escherichia coli; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Male; Melanoma; Metabolic Clearance Rate; Middle Aged; Multiple Myeloma; Neoplasms; Neuroblastoma; Osteosarcoma	1970
l-asparaginase resistance in human leukemia--asparagine synthetase. Biochemical pharmacology, 1969, Volume: 18, Issue:10 Topics: Acute Disease; Asparaginase; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Chronic Disease; Escherichia coli; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Ligases; Time Factors	1969
Studies of resistance to L-asparaginase in human leukemia. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33 Topics: Asparaginase; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Drug Resistance; Escherichia coli; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Leukocytes; Ligases	1970
Immunosuppressive action of L-asparaginase. Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:3 Topics: Animals; Antibody Formation; Antigens; Asparaginase; Asparagine; Bacteria; Guinea Pigs; Humans; Immunity; Immunity, Cellular; Leukemia; Lymphocyte Activation; Lymphocytes; Rats; Rodentia	1972
[Determination of asparagine synthetase in leukemic cells as indicator of successful enzyme therapy in hemoblastoses]. Deutsche medizinische Wochenschrift (1946), 1970, May-01, Volume: 95, Issue:18 Topics: Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Ligases; Mice; Thymidine; Tritium; Uridine; Valine	1970
L-asparaginase: clinical, biochemical, pharmacological, and immunological studies. Annals of internal medicine, 1971, Volume: 74, Issue:6 Topics: Adolescent; Adult; Antibody Formation; Antineoplastic Agents; Asparaginase; Asparagine; Bone Marrow Examination; Child; Child, Preschool; Cytarabine; Drug Hypersensitivity; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisone; Remission, Spontaneous	1971
Amino acid requirements in vitro of human leukemic cells. Cancer research, 1971, Volume: 31, Issue:11 Topics: Amino Acids; Asparaginase; Asparagine; Cells, Cultured; Culture Media; Cysteine; Female; Glutamine; Histidine; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Tritium; Tyrosine; Uridine	1971
Treatment of acute leukemia with L-asparaginase--preliminary results on 84 cases. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1970, Volume: 33 Topics: Acute Disease; Asparaginase; Asparagine; Blood Coagulation Disorders; Cells, Cultured; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Daunorubicin; Humans; Kidney Diseases; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Liver Function Tests; Methotrexate; Prednisone; Valine; Vincristine	1970
Sensitivity to L-asparaginase and amino acid metabolism. Journal of the National Cancer Institute, 1970, Volume: 44, Issue:5 Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; Culture Techniques; Female; Formates; Glutamine; Half-Life; Humans; Leukemia; Leukemia, Experimental; Male; Mice; Neoplasms; Rats; Spleen; Thymidine; Time Factors; Tritium	1970
Amino acid dependent cancers: L-asparagine in leukemia. Connecticut medicine, 1968, Volume: 32, Issue:8 Topics: Animals; Asparagine; Child; Guinea Pigs; Humans; Leukemia	1968