Compounds > asparagine

asparagine and Hypoxia

asparagine has been researched along with Hypoxia in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (63.64)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Jucht, AE; Pickel, C; Scholz, CC; Volkova, YL; Wenger, RH1
Cai, Y; Cao, T; Chen, J; Du, F; Fan, D; Han, W; Liu, H; Nie, Y; Qian, M; Tian, D; Wu, K; Xia, L; Yi, X1
Lee, SH; Ryu, SE1
Lee, BL; Lee, MK; Li, SH; Park, JW; Shin, DH; Yang, SW1
Davies, SL; Flashman, E; Schofield, CJ; Yeoh, KK1
McElwain, JC; Taylor, CT1
Gorman, JJ; Lando, D; Peet, DJ; Whitelaw, ML1
Bhasker, CR; Nanduri, J; Prabhakar, NR; Semenza, GL; Yuan, G1
Bhattacharya, S; Bullock, AN; Elkins, JM; Gleadle, JM; Hewitson, KS; McNeill, LA; Oldham, NJ; Pugh, CW; Ratcliffe, PJ; Riordan, MV; Schofield, CJ; Tian, YM; Welford, RW1
Kaelin, WG1
Bruick, RK; Gorman, JJ; Lando, D; Peet, DJ; Whelan, DA; Whitelaw, ML1

Reviews

4 review(s) available for asparagine and Hypoxia

ArticleYear
The Asparagine Hydroxylase FIH: A Unique Oxygen Sensor.
    Antioxidants & redox signaling, 2022, Volume: 37, Issue:13-15

    Topics: Asparagine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mixed Function Oxygenases; Oxygen; Repressor Proteins; Transcription Factors

2022
Ancient atmospheres and the evolution of oxygen sensing via the hypoxia-inducible factor in metazoans.
    Physiology (Bethesda, Md.), 2010, Volume: 25, Issue:5

    Topics: Adaptation, Physiological; Anaerobiosis; Animals; Asparagine; Atmosphere; Biological Evolution; Cell Hypoxia; History, Ancient; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Mixed Function Oxygenases; Oxygen; p300-CBP Transcription Factors; Procollagen-Proline Dioxygenase; Transcription, Genetic

2010
Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation.
    European journal of biochemistry, 2003, Volume: 270, Issue:5

    Topics: Asparagine; Hydroxylation; Hypoxia; Oxygen; Proline; Transcription Factors

2003
How oxygen makes its presence felt.
    Genes & development, 2002, Jun-15, Volume: 16, Issue:12

    Topics: Animals; Asparagine; DNA-Binding Proteins; Epidermal Growth Factor; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Models, Biological; Nuclear Proteins; Oxygen; Proline; Protein Structure, Tertiary; Transcription Factors; Transcriptional Activation

2002

Other Studies

7 other study(ies) available for asparagine and Hypoxia

ArticleYear
SOX12 promotes colorectal cancer cell proliferation and metastasis by regulating asparagine synthesis.
    Cell death & disease, 2019, 03-11, Volume: 10, Issue:3

    Topics: Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Biomarkers, Tumor; Caco-2 Cells; Cell Movement; Cell Proliferation; Cohort Studies; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glutaminase; HCT116 Cells; HT29 Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Prognosis; SOXC Transcription Factors; Transaminases; Transplantation, Heterologous; Up-Regulation

2019
Monoclonal antibody-based screening assay for factor inhibiting hypoxia-inducible factor inhibitors.
    Journal of biomolecular screening, 2008, Volume: 13, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Asparagine; Biological Assay; Enzyme-Linked Immunosorbent Assay; Freund's Adjuvant; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred BALB C; Rabbits; Repressor Proteins; Sensitivity and Specificity; Substrate Specificity

2008
Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.
    The FEBS journal, 2009, Volume: 276, Issue:13

    Topics: Animals; Asparagine; Cell Line; Erythropoietin; Gene Expression Regulation; Genes, Reporter; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; I-kappa B Proteins; Mixed Function Oxygenases; NF-kappa B; NF-KappaB Inhibitor alpha; Oxygen; Repressor Proteins; RNA, Small Interfering; Tumor Necrosis Factor-alpha; Two-Hybrid System Techniques

2009
Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
    The Biochemical journal, 2010, Mar-15, Volume: 427, Issue:1

    Topics: Ankyrin Repeat; Ascorbic Acid; Asparagine; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Ketoglutaric Acids; Peptide Fragments; Procollagen-Proline Dioxygenase; Reducing Agents; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2010
Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: Animals; Asparagine; Benzylamines; Blotting, Northern; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cell Nucleus; DNA; Dose-Response Relationship, Drug; E1A-Associated p300 Protein; Enzyme Activation; Gene Expression Regulation; Genes, Reporter; Glutathione Transferase; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; MAP Kinase Signaling System; Nuclear Proteins; Oligonucleotides; Oxygen; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction; Sulfonamides; Time Factors; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine 3-Monooxygenase

2005
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
    The Journal of biological chemistry, 2002, Jul-19, Volume: 277, Issue:29

    Topics: Amino Acid Sequence; Asparagine; Biological Evolution; Cloning, Molecular; Cobalt; DNA-Binding Proteins; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Ketoglutaric Acids; Mannose-6-Phosphate Isomerase; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Nuclear Proteins; Peptide Fragments; Protein Conformation; Repressor Proteins; Sequence Alignment; Spectrometry, Mass, Electrospray Ionization; Transcription Factors; Transcriptional Activation; Yeasts; Zinc

2002
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor.
    Genes & development, 2002, Jun-15, Volume: 16, Issue:12

    Topics: Amino Acid Sequence; Animals; Asparagine; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Glutathione Transferase; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Iron; Ketoglutaric Acids; Mass Spectrometry; Mice; Mixed Function Oxygenases; Molecular Sequence Data; Oxygen; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Repressor Proteins; Sequence Homology, Amino Acid; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection

2002