Compounds > asparagine

asparagine and Gaucher Disease

asparagine has been researched along with Gaucher Disease in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grabowski, GA; Liou, B1
Asano, N; Chang, HH; Fan, JQ; Ichikawa, Y; Ishii, S1
Chung, S; Do, H; Kornfeld, SA; Powe, A; Steet, RA; Wustman, B1
Ben Khelifa, S; Bonnet, V; Chkioua, L; Dandana, A; Ferchichi, S; Froissart, R; Jaidane, Z; Laradi, S; Maire, I; Miled, A; Monastiri, K1
Dorland, L; Hull, WE; Michalski, JC; Montreuil, J; Strecker, G; Van Halbeek, H; Veldink, GA; Vliegenthart, JF1
Aerts, JM; Barranger, JA; Sa Miranda, MC; Tager, JM; van den Berg, M; van Weely, S1

Other Studies

6 other study(ies) available for asparagine and Gaucher Disease

ArticleYear
Participation of asparagine 370 and glutamine 235 in the catalysis by acid beta-glucosidase: the enzyme deficient in Gaucher disease.
    Molecular genetics and metabolism, 2009, Volume: 97, Issue:1

    Topics: 2,4-Dinitrophenol; Amino Acid Substitution; Asparagine; Azides; Biocatalysis; Catalytic Domain; Enzyme Activation; Gaucher Disease; Glucosylceramidase; Glutamine; Glycosylation; Hydrogen-Ion Concentration; Hydrolysis; Mutant Proteins; Phosphatidylserines; Structure-Activity Relationship; Substrate Specificity; Taurocholic Acid

2009
Hydrophilic iminosugar active-site-specific chaperones increase residual glucocerebrosidase activity in fibroblasts from Gaucher patients.
    The FEBS journal, 2006, Volume: 273, Issue:17

    Topics: Amino Acid Substitution; Asparagine; Binding Sites; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Gaucher Disease; Glucosylceramidase; Humans; Imino Sugars; Molecular Chaperones; Serine

2006
The iminosugar isofagomine increases the activity of N370S mutant acid beta-glucosidase in Gaucher fibroblasts by several mechanisms.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-12, Volume: 103, Issue:37

    Topics: Asparagine; Binding Sites; Catalysis; Cells, Cultured; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gaucher Disease; Glucosylceramidase; Humans; Hydrogen-Ion Concentration; Imino Pyranoses; Lysosomes; Mutation; Piperidines; Protein Folding; Serine; Sodium Dodecyl Sulfate

2006
[Molecular analysis of the p.Asn 370 Ser mutation in Gaucher disease].
    Pathologie-biologie, 2008, Volume: 56, Issue:2

    Topics: Amino Acid Substitution; Asparagine; Diagnosis, Differential; DNA; DNA Primers; Exons; Gaucher Disease; Glucosylceramidase; Humans; Mutation; Polymerase Chain Reaction; Restriction Mapping; Serine

2008
Structure elucidation of oligomannoside-type asparagine-bound carbohydrate chains of glycoproteins by 500 MHz 1H NMR spectroscopy.
    FEBS letters, 1980, Nov-17, Volume: 121, Issue:1

    Topics: Asparagine; Gaucher Disease; Glycopeptides; Glycoproteins; Humans; Magnetic Resonance Spectroscopy; Mannosides

1980
Role of pH in determining the cell-type-specific residual activity of glucocerebrosidase in type 1 Gaucher disease.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:3

    Topics: Amino Acid Sequence; Asparagine; Cells, Cultured; Fibroblasts; Gaucher Disease; Genotype; Glucosylceramidase; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Kinetics; Mutation; Reference Values; Serine; Skin

1993