asparagine has been researched along with Experimental Neoplasms in 66 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 64 (96.97) | 18.7374 |
1990's | 1 (1.52) | 18.2507 |
2000's | 1 (1.52) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Abeles, RH; Foxman, BM; Stern, AM; Tashjian, AH | 1 |
BROOME, JD | 5 |
MCCOY, TA; ORR, GR; PATTERSON, MK | 1 |
LORINCZ, AB; RYAN, WL | 1 |
SCHINDLER, R | 1 |
MASHBURN, LT; WRISTON, JC | 1 |
Aldrich, CJ; Anthony, TG; Bunpo, P; Durden, DL; Goodwin, LO; McNurlan, MA; Mileva, I; Oberle, LM; Reinert, RB; Wang, XP; Wek, RC; Wek, SA | 1 |
Borella, L; Hiramoto, R; Journey, LJ | 1 |
Berezov, TT | 1 |
Dennis, JW; Schirrmacher, V; Waller, CA | 1 |
Chen, KY | 1 |
Logue, LW; Mokotoff, M | 1 |
Anderson, DR; Grimes, WJ | 1 |
Edman, P; Sjöholm, I | 1 |
Gabel, CA; Kornfeld, S | 1 |
Hageman, JJ; Koomen, GJ; Pandit, UK; Wanner, MJ | 1 |
Coleman, PS; Lavietes, BB | 1 |
Chakrabarty, SL; Manna, S; Sadhukhan, R; Sinha, A | 1 |
Banks, GT; Bascomb, S; Bettelheim, KA; Fleming, A; Skarstedt, MT | 1 |
Cooney, DA; Homan, ER; Jayaram, HN; Milman, HA; Rosenbluth, RJ | 1 |
Brynes, S; Burckart, GJ; Mokotoff, M | 1 |
Davidson, L; Kitto, GB; Mason, M; Smith, G; Thiet, TQ | 1 |
Davies, MR; Lambert, LP; Marshall, RD | 1 |
Bagaglio, JF; Mokotoff, M; Parikh, BS | 1 |
Bagaglio, JF; Brynes, S; Mokotoff, M | 1 |
Korus, RA; O'Driscoll, KF; Ohnuma, T; Walczack, IM | 1 |
Abuchowski, A; Davis, FF; McCoy, JR; Palczuk, NC; van Es, T | 1 |
Chlopkiewicz, B; Koziorowska, J | 1 |
Breitman, ML; Dennis, JW; Kerbel, RS; Laferté, S; Waghorne, C | 1 |
Arumugham, RG; Hsieh, TC; Laine, RA; Tanzer, ML | 1 |
Carver, JP; Dell, A; Dennis, JW; Fukuda, M; Laferté, S | 1 |
Alpar, HO; Lewis, DA | 1 |
Cooney, D; Hersh, LS; Murphy, GP; Sampson, D | 1 |
Cooney, DA; Milman, HA | 1 |
Orr, GR; Patterson, MK | 1 |
Baliga, BS; Borek, E; Srinivasan, PR; Weinstein, IB | 1 |
Abbondanza, A; Bonetti, E; Della Corte, E; Stirpe, F | 1 |
Knox, WE; Kupchik, HZ | 1 |
Grunberger, D; Morris, HP; Srinivasan, D; Srinivasan, PR; Weinstein, IB | 1 |
Chou, TC; Handschumacher, RE | 1 |
Summers, WP | 1 |
Ryan, WL; Sornson, HC | 1 |
Chang, PK; Handschumacher, RE; Sciarini, LJ | 1 |
Murthy, MR; Roux, H; Thenot, JP | 1 |
Chang, TM | 1 |
Cameron, T; Cooney, DA; Homan, E; Schaeppi, U | 1 |
Cook, MM; Hilleman, MR; Larson, VM; Shen, TY; Tytell, AA; Wagner, AF | 1 |
Bachynsky, N; Prager, MD | 1 |
Hayaishi, O; Honjo, T | 1 |
Jacobasch, KH | 1 |
Dworak, JE; Ryan, WL | 1 |
Boyd, JW; Phillips, AW | 1 |
Grossowicz, N; Lichtenstein, N; Schlesinger, M | 1 |
Chaudhuri, TK; Winchell, HS | 1 |
Broome, JD; Reeves, JY; Schwartz, JH | 1 |
Dixon, RL; Lee, IP; Woods, JS | 1 |
Capizzi, RL; Cooney, DA; Handschumacher, RE | 1 |
Gordon, CS; Mashburn, LT | 1 |
Dixon, RL; Woods, JS | 1 |
Kidd, JG; Sobin, LH | 1 |
Wriston, JC; Yellin, TO | 1 |
Hempel, K; Männl, HF | 1 |
4 review(s) available for asparagine and Experimental Neoplasms
Article | Year |
---|---|
[Asparagine biosynthesis and tumor growth].
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Glutamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Liver Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Rats; Transaminases | 1982 |
Immobilization of enzymes, adsorbents, or both within semipermeable microcapsules (artificial cells) for clinical and experimental treatment of metabolite-related disorders.
Topics: Acatalasia; Administration, Oral; Animals; Asparaginase; Asparagine; Catalase; Disease Models, Animal; Enzymes; Injections, Intraperitoneal; Kidney Failure, Chronic; Kidneys, Artificial; Lymphoma, Non-Hodgkin; Membranes, Artificial; Metabolic Diseases; Mice; Neoplasms, Experimental; Permeability; Pharmaceutic Aids; Sarcoma, Experimental; Solubility; Urea; Urease; Uremia | 1973 |
[Nutritional requirement of cancer cells: inhibition of the growth of cancer cells by L-asparaginase].
Topics: Animals; Asparaginase; Asparagine; Escherichia coli; Guinea Pigs; Humans; Leukemia; Mutation; Neoplasms; Neoplasms, Experimental | 1970 |
[Enzyme therapy of malignant tumors].
Topics: Animals; Asparaginase; Asparagine; Glutaminase; Guinea Pigs; Humans; Leukemia; Mice; Neoplasms; Neoplasms, Experimental; Rabbits; Rats | 1969 |
62 other study(ies) available for asparagine and Experimental Neoplasms
Article | Year |
---|---|
DL-threo-beta-Fluoroaspartate and DL-threo-beta-fluoroasparagine: selective cytotoxic agents for mammalian cells in culture.
Topics: Amino Acids; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Cells, Cultured; Models, Molecular; Neoplasms, Experimental; Rats; Stereoisomerism; Structure-Activity Relationship; X-Ray Diffraction | 1982 |
Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. II. Lymphoma 6C3HED cells cultured in a medium devoid of L-asparagine lose their susceptibility to the effects of guinea pig serum in vivo.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Complement System Proteins; Disease Susceptibility; Endopeptidases; Guinea Pigs; Lymphocyte Count; Lymphoma; Mice; Neoplasms, Experimental; Pyrimidines | 1963 |
ASPARAGINE-C14 AND GLUTAMINE-C14 FROM ANIMAL CELL PROTEIN AND THEIR CHEMICAL DEGRADATION.
Topics: Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Chromatography; Glutamine; Ion Exchange Resins; Malates; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Proteins; Research; Sarcoma; Sarcoma, Experimental | 1963 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
QUANTITATIVE COLONIAL GROWTH OF MAMMALIAN CELLS IN FIBRIN CELLS.
Topics: Asparagine; Fibrin; Folic Acid; Immune Sera; Mast Cells; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Serine; Thrombin; Tissue Culture Techniques | 1964 |
TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Bacillus; Electrophoresis; Escherichia coli; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma; Sarcoma, Experimental | 1964 |
Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase.
Topics: Animals; Asparaginase; Asparagine; Escherichia coli; Female; Glutamine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Protein Serine-Threonine Kinases; Wolinella | 2006 |
In vivo and in vitro effects of the L-asparaginase fraction of guinea pig serum on the 6C3HED ascites lymphosarcoma.
Topics: Aminohydrolases; Animals; Antineoplastic Agents; Asparagine; Carcinoma, Ehrlich Tumor; Guinea Pigs; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Microscopy, Electron; Microscopy, Fluorescence; Neoplasms, Experimental; Nucleosides; Spleen; Tritium | 1966 |
Identification of asparagine-linked oligosaccharides involved in tumor cell adhesion to laminin and type IV collagen.
Topics: Animals; Asparagine; Carbohydrate Conformation; Carbohydrate Sequence; Cell Adhesion; Cell Line; Collagen; Laminin; Lectins; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Oligosaccharides; Receptors, Collagen; Receptors, Immunologic; Receptors, Laminin | 1984 |
Differences in the mode of regulation of ornithine decarboxylase activity in undifferentiated versus differentiated mouse N-18 neuroblastoma cells.
Topics: Animals; Asparagine; Bucladesine; Carboxy-Lyases; Cell Differentiation; Cell Line; Culture Media; Enzyme Induction; Mice; Neoplasms, Experimental; Neuroblastoma; Neurons; Ornithine Decarboxylase | 1980 |
Potential inhibitors of L-asparagine biosynthesis. 5. Electrophilic amide analogues of (S)-2,3-diaminopropionic acid.
Topics: Alanine; Amides; Animals; Asparagine; beta-Alanine; Cells, Cultured; Chemical Phenomena; Chemistry; Depression, Chemical; Neoplasms, Experimental; Rats | 1981 |
Heterogeneity of asparagine-linked oligosaccharides of five glycosylation sites on immunoglobulin M heavy chain from mineral oil plasmacytoma 104E.
Topics: Amino Acid Sequence; Amino Acids; Animals; Asparagine; Carbohydrates; Cell Line; Glycopeptides; Humans; Immunoglobulin Heavy Chains; Immunoglobulin M; Mice; Mineral Oil; Neoplasms, Experimental; Oligosaccharides; Plasmacytoma; Species Specificity | 1982 |
Acrylic microspheres in vivo VI: antitumor effect of microparticles with immobilized L-asparaginase against 6C3HED lymphoma.
Topics: Acrylates; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Enzymes, Immobilized; Lymphoma; Mice; Microspheres; Neoplasms, Experimental; Time Factors | 1983 |
L-Asparaginase: discovery and development as a tumor-inhibitory agent.
Topics: Animals; Asparaginase; Asparagine; Cell Line; Escherichia coli; Guinea Pigs; Half-Life; History, 20th Century; Humans; Leukemia; Lymphoma; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Sarcoma, Experimental | 1981 |
Lysosomal enzyme phosphorylation in mouse lymphoma cell lines with altered asparagine-linked oligosaccharides.
Topics: Animals; Asparagine; Glycoside Hydrolases; Hydrolases; Lymphoma; Lysosomes; Mannosephosphates; Mice; Mutation; Neoplasms, Experimental; Oligosaccharides; Phosphorylation | 1982 |
Potential carcinostatics. 4. Synthesis and biological properties of erythro- and threo-beta-fluoroaspartic acid and erythro-beta-fluoroasparagine.
Topics: Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Female; Leukemia L5178; Lung Neoplasms; Male; Mice; Models, Molecular; Molecular Conformation; Neoplasms, Experimental | 1980 |
The role of lipid metabolism in neoplastic differentiation.
Topics: Animals; Asparagine; Cell Transformation, Neoplastic; Cholesterol; Citric Acid Cycle; Feedback; Glucose; Glutamine; Humans; Lipids; Models, Biological; Neoplasms, Experimental; Nitrogen; Oxygen Consumption; Polyamines | 1980 |
Purification, characterization and antitumor activity of L-asparaginase isolated from Pseudomonas stutzeri MB-405.
Topics: Amino Acids; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Isoelectric Point; Kinetics; Male; Metals; Mice; Molecular Weight; Neoplasms, Experimental; Pseudomonas; Substrate Specificity | 1995 |
The properties and large-scale production of L-asparaginase from citrobacter.
Topics: Animals; Asparaginase; Asparagine; Citrobacter; Culture Media; Drug Evaluation, Preclinical; Enterobacteriaceae; Fermentation; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Lymphoma, Non-Hodgkin; Mice; Molecular Weight; Neoplasms, Experimental; Oxygen; Stereoisomerism; Temperature; Zea mays | 1975 |
DON, CONV and DONV-II. Inhibition of L-'asparagine synthetase in vivo.
Topics: Amino Acids; Animals; Asparagine; Aspartate-Ammonia Ligase; Aspartic Acid; Azo Compounds; Cells, Cultured; Diazooxonorleucine; DNA; Formates; Glutamine; Levulinic Acids; Ligases; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Pancreas | 1976 |
Potential inhibitors of L-asparagine biosynthesis. 4. Substituted sulfonamide and sulfonylhydrazide analogues of L-asparagine.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Hydrazines; In Vitro Techniques; Leukemia, Experimental; Ligases; Liver Neoplasms; Mice; Neoplasms, Experimental; Rats; Structure-Activity Relationship; Sulfonamides | 1978 |
Tumor inhibitory and non-tumor inhibitory L-asparaginases from Pseudomonas geniculata.
Topics: Animals; Antigens, Bacterial; Asparaginase; Asparagine; Cross Reactions; Glutamine; Hydrogen-Ion Concentration; Mice; Molecular Weight; Neoplasms, Experimental; Pseudomonas; Substrate Specificity | 1979 |
L-asparaginyl-tRNA synthetase and L-asparagine synthetase activities of L-asparaginase-sensitive and -resistant forms of the mouse Gardner lymphoma 6C3HED.
Topics: Amino Acyl-tRNA Synthetases; Animals; Antineoplastic Agents; Ascitic Fluid; Asparaginase; Asparagine; Aspartate-Ammonia Ligase; Cell Transformation, Neoplastic; Cells, Cultured; Horses; Ligases; Lymphoma; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Time Factors | 1979 |
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
Topics: Animals; Asparagine; Aspartic Acid; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Hydroxy Acids; Ligases; Liver Neoplasms; Male; Molecular Conformation; Neoplasms, Experimental; Rats; Stereoisomerism; Structure-Activity Relationship | 1975 |
Potential inhibitors of L-asparagine biosynthesis. 3. Aromatic sulfonyl fluoride analogs of L-asparagine and L-glutamine.
Topics: Animals; Asparagine; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Depression, Chemical; Glutamine; Liver Neoplasms; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Sulfones | 1975 |
Gel entrapped L-asparaginase: kinetic behavior and antitumor activity.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Aspartic Acid; Drug Stability; Escherichia coli; Gels; Hydrogen-Ion Concentration; Kinetics; Lymphoma; Mice; Neoplasms, Experimental; Particle Size | 1975 |
Treatment of L5178Y tumor-bearing BDF1 mice with a nonimmunogenic L-glutaminase-L-asparaginase.
Topics: Amidohydrolases; Animals; Antibody Formation; Asparaginase; Asparagine; Drug Therapy, Combination; Glutaminase; Glutamine; Metabolic Clearance Rate; Mice; Neoplasms, Experimental; Polyethylene Glycols | 1979 |
Role of amino acid depletion in combined treatment of neoplastic cells with methotrexate and L-asparaginase.
Topics: Animals; Asparaginase; Asparagine; Autoradiography; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug; Haplorhini; L Cells; Leukemia L1210; Methotrexate; Neoplasms, Experimental | 1975 |
Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis.
Topics: Animals; Asparagine; Carbohydrate Conformation; Cell Line; Cell Transformation, Neoplastic; Glucosyltransferases; Glycosylation; Lysosomal Membrane Proteins; Membrane Glycoproteins; Membrane Proteins; Mice; Mutation; N-Acetylglucosaminyltransferases; Neoplasm Metastasis; Neoplasms, Experimental; Oligosaccharides; Structure-Activity Relationship | 1987 |
Structures of the asparagine-linked sugar chains of laminin.
Topics: Animals; Asparagine; Basement Membrane; Carbohydrate Conformation; Chromatography, Affinity; Chromatography, Gel; Galactose; Glucosamine; Glycopeptides; Laminin; Mice; Molecular Weight; Neoplasms, Experimental; Oligosaccharides | 1986 |
Asn-linked oligosaccharides in lectin-resistant tumor-cell mutants with varying metastatic potential.
Topics: Asparagine; Cell Line; Chromatography, Affinity; Chromatography, High Pressure Liquid; Concanavalin A; Lectins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Mutation; Neoplasms, Experimental; Oligosaccharides; Phenotype | 1986 |
Therapeutic efficacy of asparaginase encapsulated in intact erythrocytes.
Topics: Animals; Asparaginase; Asparagine; Erythrocytes; Female; Glutamine; Lymphoma; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1985 |
A new technique employing extracorporeal chemotherapy.
Topics: Animals; Asparaginase; Asparagine; Chemotherapy, Cancer, Regional Perfusion; Dogs; Haplorhini; Immunosuppression Therapy; Lymphocytes; Methylmethacrylates; Mitogens; Neoplasms, Experimental; Papio; Thymidine; Tritium | 1972 |
The distribution of L-asparagine synthetase in the principal organs of several mammalian and avian species.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Autoanalysis; Brain; Carbon Radioisotopes; Cats; Cattle; Chickens; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Kidney; Leukemia; Ligases; Liver; Lung; Male; Mice; Neoplasms, Experimental; Ovary; Pancreas; Rabbits; Rats; Sheep; Spleen; Swine; Temperature; Testis; Turkeys | 1974 |
Asparagine biosynthesis by the Novikoff Hepatoma isolation, purification, property, and mechanism studies of the enzyme system.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Ammonium Chloride; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; Carcinoma, Hepatocellular; Diphosphates; Female; Glutamine; Hydrogen-Ion Concentration; Hydroxamic Acids; Hydroxylamines; Liver Neoplasms; Magnesium; Manganese; Neoplasms, Experimental; Potassium; Rats | 1968 |
Differences in the transfer RNA's of normal liver and Novikoff hepatoma.
Topics: Amino Acids; Animals; Asparagine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Ligases; Liver; Liver Neoplasms; Methods; Neoplasms, Experimental; Rats; RNA, Transfer; Tritium; Tyrosine | 1969 |
The regulation of L-asparaginase activity in rats and mice. Effects of normal and malignant growth, of sex and of dietary changes.
Topics: Age Factors; Animals; Animals, Newborn; Asparaginase; Asparagine; Carcinoma, Hepatocellular; Castration; Diet; Dietary Proteins; Estradiol; Female; Liver; Liver Neoplasms; Liver Regeneration; Male; Mice; Neoplasms, Experimental; Rats; Sex Factors; Starvation | 1969 |
Assays of glutamine and its aminotransferase with the enol-borate of phenylpyruvate.
Topics: Age Factors; Animals; Asparagine; Boric Acids; Carcinoma, Hepatocellular; Cold Temperature; Drug Stability; Female; Fetus; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver Neoplasms; Liver Regeneration; Male; Mammary Neoplasms, Experimental; Mathematics; Methods; Neoplasms, Experimental; Organ Specificity; Phenylpyruvic Acids; Rats; Sex Factors; Solubility; Spectrophotometry; Time Factors; Transaminases; Ultraviolet Rays | 1970 |
Alterations in specific transfer ribonucleic acids in a spectrum of hepatomas.
Topics: Animals; Asparagine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Diploidy; Escherichia coli; Genetic Code; Hindlimb; Histidine; Ligases; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Phenylalanine; Polynucleotides; Polyploidy; Rats; Ribosomes; RNA, Transfer; Tritium; Tyrosine; Ultracentrifugation | 1971 |
Production of L-asparagine by tumor cells and the effect of asparagine analogs.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Azo Compounds; Bromine; Carbon Isotopes; Carcinoma, Hepatocellular; Chlorine; Glutamine; Kinetics; Leukemia, Experimental; Liver Neoplasms; Lymphoma, Non-Hodgkin; Mast Cells; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma 180 | 1972 |
Chemically induced mutation of L-5178Y mouse leukemia cells from asparagine-dependence to asparagine-independence.
Topics: Acridines; Animals; Asparagine; Cell Division; Cell Line; Cell Survival; Clone Cells; Gene Frequency; Leukemia, Lymphoid; Mesylates; Mice; Mutagens; Mutation; Neoplasms, Experimental; Nitrosoguanidines; Time Factors | 1973 |
Enhancement of asparaginase-induced regression of the 6C3HED lymphosarcoma by protein-free diet.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Diet Therapy; Dietary Proteins; Escherichia coli; Female; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred C3H; Neoplasms, Experimental | 1973 |
New asparagine analogs.
Topics: Amino Acids, Diamino; Animals; Asparaginase; Asparagine; Cells, Cultured; Escherichia coli; Kinetics; Leukemia, Experimental; Lymphoma; Neoplasms, Experimental; Stereoisomerism; Structure-Activity Relationship | 1973 |
Isoacceptor tRNAs for glutamate, glutamine, aspartate and asparagine in calf brain.
Topics: Animals; Asparagine; Aspartic Acid; Brain; Carbon Radioisotopes; Cattle; Chromatography; Chromatography, Gel; Escherichia coli; Glutamates; Glutamine; Humans; Liver; Liver Regeneration; Lymphocytes; Male; Mice; Neoplasms, Experimental; Organ Specificity; Plasmacytoma; Rats; RNA, Transfer; Species Specificity; Spectrophotometry, Ultraviolet | 1974 |
The measurement of 4-( 14 C)-L-asparagine in body fluids and tissues: methodology and application.
Topics: Amination; Animals; Asparaginase; Asparagine; Aspartate Aminotransferases; Aspartic Acid; Carbon Isotopes; Cyclophosphamide; Decarboxylation; Diet; Dogs; Female; Hydrolysis; Ketoglutaric Acids; Lymphoma; Lymphoma, Non-Hodgkin; Malate Dehydrogenase; Methods; Neoplasms, Experimental; Pronase; Proteins; Zinc | 1973 |
Failure of Shier's chemical vaccine to protect BALB-c mice against transplant and chemically induced tumors.
Topics: Age Factors; Animals; Asparagine; Cell Line; Female; Glycopeptides; Hemagglutination; Lectins; Male; Methylcholanthrene; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasm Transplantation; Neoplasms, Experimental; Vaccination; Vaccines | 1974 |
Studies on the mechanism of tumor inhibition by L-asparaginase. Effects of the enzyme on asparagine levels in the blood, normal tissues, and 6C3HED lymphomas of mice: differences in asparagine formation and utilization in asparaginase-sensitive and -resis
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Aspartic Acid; Cell-Free System; Culture Techniques; Escherichia coli; Female; Glutamine; Leucine; Lymphoma; Male; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rabbits; Rats | 1968 |
Factors which may influence the effectiveness of L-asparaginases as tumor inhibitors.
Topics: Animals; Antineoplastic Agents; Asparaginase; Asparagine; Escherichia coli; Kinetics; Liver; Lymphoma; Metabolic Clearance Rate; Mice; Neoplasms, Experimental; Rodentia; Spleen | 1968 |
Asparagine synthetase in normal and malignant tissues: correlation with tumor sensitivity to asparaginase.
Topics: Adenosine Triphosphate; Animals; Asparaginase; Asparagine; Cell Nucleus; Enzyme Repression; Escherichia coli; Feedback; Glutamine; Guinea Pigs; Hydrogen-Ion Concentration; Kidney; Leukemia; Ligases; Liver; Lymphoid Tissue; Lymphoma; Lymphoma, Non-Hodgkin; Lysosomes; Mice; Microsomes; Mitochondria, Liver; Neoplasms, Experimental; Puromycin; Spleen; Stimulation, Chemical | 1968 |
Amino acids of the 6C3HED lymphosarcoma following treatment with asparaginase.
Topics: Amino Acids; Ammonia; Animals; Asparaginase; Asparagine; Aspartic Acid; Escherichia coli; Female; Glutamates; Glutamine; Glycine; Liver; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Spleen | 1970 |
Purification and properties of L-asparaginase from Serratia marcescens.
Topics: Acrylates; Ammonia; Animals; Asparaginase; Asparagine; Chromatography, DEAE-Cellulose; Cross Reactions; Culture Media; Electrophoresis, Disc; Escherichia coli; Female; Gels; Hydrogen-Ion Concentration; Hydroxyapatites; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Injections, Intraperitoneal; Lymphoma, Non-Hodgkin; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Rabbits; Sarcoma, Experimental; Serratia marcescens; Species Specificity; Spectrophotometry; Ultracentrifugation | 1971 |
Inhibition of murine tumors by carbobenzoxy derivatives of amino acids.
Topics: Amino Acids; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Benzyl Compounds; Carcinoma, Ehrlich Tumor; Cysteine; Formates; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Phenylalanine | 1971 |
Diminished oxidation of 14C-UL-L-asparagine to 14CO2 in mice and humans with tumors: a possible means for assessing efficacy of therapy?
Topics: Animals; Asparagine; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Humans; Injections, Intravenous; Leukemia, Lymphoid; Male; Mice; Multiple Myeloma; Neoplasms; Neoplasms, Experimental; Oxidation-Reduction | 1970 |
Two L-asparaginases from E. coli and their action against tumors.
Topics: Amidohydrolases; Animals; Asparagine; Escherichia coli; Lymphoma; Mice; Neoplasms, Experimental | 1966 |
L-asparaginase: early findings and current studies on the metabolism of L-asparagine in lymphoma cells.
Topics: Amino Acyl-tRNA Synthetases; Asparaginase; Asparagine; Aspartic Acid; Cell Line; Chromatography, DEAE-Cellulose; Drug Resistance; Kinetics; Leucine; Lymphoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Transfer | 1970 |
Asparagine incorporation into the DNA of hepatic and 6C3HED murine lymphosarcoma cells.
Topics: Amino Acids; Aminohydrolases; Animals; Asparagine; Aspartic Acid; Carbon Isotopes; DNA; DNA, Neoplasm; Liver; Lymphoma, Non-Hodgkin; Male; Mice; Neoplasms, Experimental | 1970 |
Evaluation of L-asparagine metabolism in animals and man.
Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Dogs; Erythrocytes; Fluorometry; Hepatectomy; Humans; Hypophysectomy; Leukemia, Experimental; Lymphoma; Lymphoma, Non-Hodgkin; Methods; Mice; Neoplasms, Experimental; Rats; Renal Dialysis; Spectrophotometry | 1970 |
The effects of L-asparaginase on the amino acid incorporation of mouse lymphoid tumors.
Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Carbon Isotopes; Leucine; Lymphoma; Mice; Neoplasms, Experimental; Tritium | 1968 |
Uptake of asparagine C-14 into the pyrimidine synthesis pathway of guinea pig serum sensitive 6C3HED lymphosarcoma cells.
Topics: Animals; Asparaginase; Asparagine; Aspartic Acid; Carbon Isotopes; Culture Techniques; DNA, Neoplasm; Guinea Pigs; Lymphoma, Non-Hodgkin; Male; Mice; Neoplasms, Experimental; Pyrimidines | 1968 |
The incorporation of l-asparagine-14C by lymphoma 6C3HED cells: its inhibition by guinea pig serum.
Topics: Animals; Asparagine; Blood; Carbon Isotopes; Guinea Pigs; Lymphoma; Neoplasms, Experimental; Radionuclide Imaging | 1966 |
Antagonism of purified asparaginase from guinea pig serum toward lymphoma.
Topics: Amidohydrolases; Animals; Asparagine; Electrophoresis; Guinea Pigs; Immunization, Passive; In Vitro Techniques; Lymphoma, Non-Hodgkin; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Ultracentrifugation | 1966 |
The conversion of [3H]tyrosine to [3H]DOPA in mouse melanoma in vivo.
Topics: Animals; Asparagine; Aspartic Acid; Chromatography, Paper; Dihydroxyphenylalanine; Electrophoresis; Glutamates; Glutamine; Melanoma; Mice; Neoplasms, Experimental; Tyrosine | 1966 |