asparagine and Cataract

asparagine has been researched along with Cataract in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's3 (18.75)18.2507
2000's3 (18.75)29.6817
2010's8 (50.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Ishikawa, Y; Kato, K; Kitamura, Y; Kurimoto, E; Nakayoshi, T; Oda, A1
Barbar, EJ; David, LL; Forsythe, HM; Jara, KA; Lampi, KJ; Reardon, PN; Vetter, CJ1
Wang, H; Wu, D; Zhang, J; Zhang, T1
Mokhor, N; Pande, A; Pande, J1
Hains, PG; Truscott, RJ1
Fu, Y; Jia, X; Liu, G; Lu, X; Wang, X; Xing, B; Yang, G; Yu, H; Zhao, J1
Fujii, N; Kawaguchi, T; Sasaki, H1
Lu, Y; Luo, Y; Wang, L; Wen, W; Zhang, S1
Hooi, MY; Raftery, MJ; Truscott, RJ1
Srivastava, K; Srivastava, OP1
Carter, DA; McFadden, PN1
Boyle, D; Takemoto, L2
Boyle, D; Fujii, N; Takemoto, L1
Emmons, T; Granstrom, D; Takemoto, L1
Graeber, W1

Other Studies

16 other study(ies) available for asparagine and Cataract

ArticleYear
Identification of the Most Impactful Asparagine Residues for γS-Crystallin Aggregation by Deamidation.
    Biochemistry, 2023, 06-06, Volume: 62, Issue:11

    Topics: Asparagine; Cataract; gamma-Crystallins; Humans; Lens, Crystalline; Mutation

2023
Altered Protein Dynamics and Increased Aggregation of Human γS-Crystallin Due to Cataract-Associated Deamidations.
    Biochemistry, 2019, 10-08, Volume: 58, Issue:40

    Topics: Aged, 80 and over; Asparagine; Cataract; gamma-Crystallins; Humans; Hydrolysis; Protein Conformation, alpha-Helical; Protein Multimerization; Protein Unfolding; Scattering, Radiation

2019
A novel beaded filament structural protein 1 (BFSP1) gene mutation associated with autosomal dominant congenital cataract in a Chinese family.
    Molecular vision, 2013, Volume: 19

    Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Animals; Asian People; Asparagine; Aspartic Acid; Case-Control Studies; Cataract; Exons; Eye Proteins; Female; Genetic Linkage; Genotype; Humans; Intermediate Filament Proteins; Lens, Crystalline; Male; Molecular Sequence Data; Mutation, Missense; Pedigree; Sequence Alignment; Sequence Analysis, DNA

2013
Deamidation of Human γS-Crystallin Increases Attractive Protein Interactions: Implications for Cataract.
    Biochemistry, 2015, Aug-11, Volume: 54, Issue:31

    Topics: Asparagine; Cataract; gamma-Crystallins; Glutamine; Humans; Models, Chemical; Protein Structure, Secondary; Protein Structure, Tertiary

2015
Age-dependent deamidation of lifelong proteins in the human lens.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Asparagine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Gestational Age; Glutamine; Humans; Lens, Crystalline; Middle Aged; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2010
A novel mutation in the GJA3 (connexin46) gene is associated with autosomal dominant congenital nuclear cataract in a Chinese family.
    Molecular vision, 2011, Apr-27, Volume: 17

    Topics: Amino Acid Sequence; Asian People; Asparagine; Aspartic Acid; Base Sequence; Cataract; Chromosomes, Human, Pair 13; Connexins; Female; Genes, Dominant; Genetic Linkage; Genotype; Haplotypes; Humans; Lens, Crystalline; Lod Score; Male; Microsatellite Repeats; Molecular Sequence Data; Mutation, Missense; Pedigree

2011
Simultaneous stereoinversion and isomerization at the Asp-4 residue in βB2-crystallin from the aged human eye lenses.
    Biochemistry, 2011, Oct-11, Volume: 50, Issue:40

    Topics: Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Asparagine; beta-Crystallin B Chain; Cataract; Female; Humans; Isomerism; Lens, Crystalline; Male; Stereoisomerism

2011
Another evidence for a D47N mutation in GJA8 associated with autosomal dominant congenital cataract.
    Molecular vision, 2011, Volume: 17

    Topics: Asian People; Asparagine; Aspartic Acid; Case-Control Studies; Cataract; Connexin 26; Connexins; DNA Mutational Analysis; Exons; Eye Proteins; Female; Genes, Dominant; Genetic Linkage; Humans; Male; Models, Molecular; Mutant Proteins; Mutation, Missense; Pedigree; Polymerase Chain Reaction; Thermodynamics

2011
Racemization of two proteins over our lifespan: deamidation of asparagine 76 in γS crystallin is greater in cataract than in normal lenses across the age range.
    Investigative ophthalmology & visual science, 2012, Jun-14, Volume: 53, Issue:7

    Topics: Aged; Aging; Asparagine; Cataract; Chromatography, High Pressure Liquid; Electrophoresis, Gel, Two-Dimensional; gamma-Crystallins; Humans; Lens, Crystalline; Middle Aged; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
Existence of deamidated alphaB-crystallin fragments in normal and cataractous human lenses.
    Molecular vision, 2003, Apr-16, Volume: 9

    Topics: Aged; Aged, 80 and over; alpha-Crystallin B Chain; Amino Acid Sequence; Asparagine; Blotting, Western; Cataract; Deamination; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gas Chromatography-Mass Spectrometry; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2003
Determination of beta-isomerized aspartic acid as the corresponding alcohol.
    Journal of protein chemistry, 1994, Volume: 13, Issue:1

    Topics: Aluminum Compounds; Amino Acids; Asparagine; Aspartic Acid; Boranes; Cataract; Chymotrypsin; Crystallins; Homoserine; Humans; Indicators and Reagents; Isomerism; Lithium Compounds; Ovalbumin; Proteins; Succinimides; Tetragastrin

1994
Deamidation of alpha-A crystallin from nuclei of cataractous and normal human lenses.
    Molecular vision, 1999, Feb-19, Volume: 5

    Topics: Aged; Amides; Amino Acid Sequence; Asparagine; Cataract; Chromatography; Crystallins; Glutamine; Humans; Lens, Crystalline; Middle Aged

1999
Increased deamidation of asparagine during human senile cataractogenesis.
    Molecular vision, 2000, Sep-05, Volume: 6

    Topics: Aged; Amino Acid Sequence; Asparagine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptide Fragments

2000
Mechanism of asparagine deamidation during human senile cataractogenesis.
    Experimental eye research, 2001, Volume: 72, Issue:5

    Topics: Asparagine; Aspartic Acid; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Humans; Succinimides

2001
The sequences of two peptides from cataract lenses suggest they arise by deamidation.
    Current eye research, 1990, Volume: 9, Issue:8

    Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Cataract; Cattle; Crystallins; Deamination; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptide Fragments; Peptides; Rabbits; Radioimmunoassay; Sequence Homology, Nucleic Acid; Trypsin

1990
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1966, Dec-15, Volume: 171, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine

1966