asparagine and Aging

asparagine has been researched along with Aging in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19908 (26.67)18.7374
1990's6 (20.00)18.2507
2000's7 (23.33)29.6817
2010's7 (23.33)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Cheng, ML; Hsu, WC; Lin, G; Lin, HT; Liu, FC; Lo, CJ1
Fang, ZZ; Feng, XF; Hou, RQ; Luo, HH; Yang, XL1
Ito, S; Kashiwagi, K; Kato, G; Maeda, S1
Cheng, L; Duong, DM; Hu, WT; Kang, SS; Kwon, IS; Levey, AI; Liu, X; Liu, Z; Seyfried, NT; Song, M; Sun, YE; Wang, JZ; Ye, K; Yu, SP; Zhang, Z1
Chalisova, NI; Zakutskii, AN1
Hains, PG; Truscott, RJ1
Calzia, D; Morelli, A; Panfoli, I; Ravera, S1
Fujii, N; Kawaguchi, T; Sasaki, H1
Chen, CC; Dall'Olio, F; Franceschi, C; Slagboom, PE; Vanhooren, V; Wuhrer, M1
Hooi, MY; Raftery, MJ; Truscott, RJ1
DENNEN, DW; NIEDERPRUEM, DJ1
Chalisova, NI; Penniiaĭnen, VA1
Aitchison, L; Baybutt, H; Cancellotti, E; Manson, JC; Monaghan, P; Simpson, J; Tuzi, NL; Wiseman, F1
Groebe, K; Schrattenholz, A; Soskić, V1
Oaks, A1
Christensen, HN; Vadgama, JV1
Baudry, M; Najm, I; Schreiber, SS1
Bloemendal, H; de Jong, WW; Groenen, PJ; van Dongen, MJ; Voorter, CE1
Fujii, N1
Takemoto, LJ1
Boyle, D; Takemoto, L1
Takemoto, L1
Helliger, W; Lindner, H1
Corvol, P; Kempf, H; Nishimura, H; Wideman, RF; Xi, Z; Zhang, L1
Hosbach, HA; Kubli, E1
McKerrow, JH1
Emmons, T; Takemoto, L1
Robinson, AB; Rudd, CJ1
Arcce, CA; Barra, HS; Caputto, R; Rodriguez, JA1
Graeber, W1

Reviews

6 review(s) available for asparagine and Aging

ArticleYear
N-glycomic biomarkers of biological aging and longevity: a link with inflammaging.
    Ageing research reviews, 2013, Volume: 12, Issue:2

    Topics: Aged; Aging; Animals; Asparagine; Autoimmune Diseases; Biomarkers; Complement Pathway, Mannose-Binding Lectin; Feedback, Physiological; Glycomics; Glycosylation; Humans; Immunoglobulin G; Inflammation; Mice; Models, Theoretical; Polysaccharides; Progeria; Protein Processing, Post-Translational

2013
Nonenzymatic posttranslational protein modifications in ageing.
    Experimental gerontology, 2008, Volume: 43, Issue:4

    Topics: Aging; Asparagine; Aspartic Acid; Deamination; Glycation End Products, Advanced; Humans; Maillard Reaction; Mass Spectrometry; Oxidative Stress; Peptide Mapping; Protein Carbonylation; Protein Processing, Post-Translational; Reactive Nitrogen Species; Reactive Oxygen Species; Succinimides

2008
[Simultaneous stereoinversion, racemization and isomerization at specific amino acid residues in the proteins during aging].
    Seikagaku. The Journal of Japanese Biochemical Society, 1996, Volume: 68, Issue:10

    Topics: Aging; Asparagine; Crystallins; Humans; Stereoisomerism

1996
Age-dependent deamidation of asparagine residues in proteins.
    Experimental gerontology, 2001, Volume: 36, Issue:9

    Topics: Aging; Animals; Asparagine; Humans; Proteins

2001
Non-enzymatic, post-translational, amino acid modifications in ageing. A brief review.
    Mechanisms of ageing and development, 1979, Volume: 10, Issue:6

    Topics: Aging; Amides; Amino Acids; Animals; Asparagine; Aspartic Acid; Glutamine; Half-Life; Isomerism; Models, Biological; Oligopeptides; Proteins; Rats; Structure-Activity Relationship

1979
Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.
    Current topics in cellular regulation, 1974, Volume: 8, Issue:0

    Topics: Aging; Amides; Amino Acid Sequence; Animals; Ascorbic Acid; Asparagine; Bacterial Proteins; Biological Evolution; Cytochrome c Group; Escherichia coli; Fructose-Bisphosphate Aldolase; Glutamine; Histones; Humans; Hydrogen-Ion Concentration; Hydrolysis; Muramidase; Oxygen; Peptides; Proteins; Temperature

1974

Other Studies

24 other study(ies) available for asparagine and Aging

ArticleYear
Exploring the aging process of cognitively healthy adults by analyzing cerebrospinal fluid metabolomics using liquid chromatography-tandem mass spectrometry.
    BMC geriatrics, 2023, 04-05, Volume: 23, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Asparagine; Chromatography, Liquid; Cognition; Cohort Studies; Cysteine; Fasting; Female; Healthy Volunteers; Humans; Hydroxyindoleacetic Acid; Male; Metabolome; Middle Aged; Pantothenic Acid; Tandem Mass Spectrometry; Young Adult

2023
Interactive effects of asparagine and aspartate homeostasis with sex and age for the risk of type 2 diabetes risk.
    Biology of sex differences, 2020, 10-22, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Aging; Asian People; Asparagine; Aspartic Acid; China; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Sex Factors; Young Adult

2020
A Ser75-to-Asp phospho-mimicking mutation in Src accelerates ageing-related loss of retinal ganglion cells in mice.
    Scientific reports, 2017, 12-01, Volume: 7, Issue:1

    Topics: Aging; Amino Acid Substitution; Animals; Apoptosis; Asparagine; Cell Count; Cell Survival; Mice; Mice, Knockout; Optic Nerve Diseases; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Retinal Ganglion Cells; Serine

2017
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.
    Nature medicine, 2014, Volume: 20, Issue:11

    Topics: Aged; Aging; Alzheimer Disease; Amino Acid Sequence; Animals; Asparagine; Brain; Calpain; Caspases; Cognition; Cysteine Endopeptidases; Gene Knockout Techniques; HEK293 Cells; Humans; Memory Disorders; Mice, Transgenic; Molecular Sequence Data; Neurofibrillary Tangles; Neurotoxins; Phosphorylation; Protein Structure, Tertiary; Solubility; Synapses; tau Proteins; Up-Regulation

2014
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
    Cell biology international, 2008, Volume: 32, Issue:12

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation

2008
Age-dependent deamidation of lifelong proteins in the human lens.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Asparagine; Cataract; Chromatography, High Pressure Liquid; Crystallins; Deamination; Gestational Age; Glutamine; Humans; Lens, Crystalline; Middle Aged; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2010
Accelerated removal of deamidated proteins and endogenous electric fields: possible implications.
    General physiology and biophysics, 2010, Volume: 29, Issue:3

    Topics: Aging; Asparagine; Biophysical Phenomena; Electricity; Glutamine; Isoelectric Point; Models, Biological; Peptide Hydrolases; Protein Folding; Proteins

2010
Simultaneous stereoinversion and isomerization at the Asp-4 residue in βB2-crystallin from the aged human eye lenses.
    Biochemistry, 2011, Oct-11, Volume: 50, Issue:40

    Topics: Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Asparagine; beta-Crystallin B Chain; Cataract; Female; Humans; Isomerism; Lens, Crystalline; Male; Stereoisomerism

2011
Racemization of two proteins over our lifespan: deamidation of asparagine 76 in γS crystallin is greater in cataract than in normal lenses across the age range.
    Investigative ophthalmology & visual science, 2012, Jun-14, Volume: 53, Issue:7

    Topics: Aged; Aging; Asparagine; Cataract; Chromatography, High Pressure Liquid; Electrophoresis, Gel, Two-Dimensional; gamma-Crystallins; Humans; Lens, Crystalline; Middle Aged; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
CONTROL OF GLUTAMATE DEHYDROGENASE IN THE BASIDIOMYCETE SCHIZOPHYLLUM COMMUNE.
    Life sciences (1962), 1965, Volume: 4

    Topics: Aging; Amino Acids; Asparagine; Basidiomycota; Glutamate Dehydrogenase; Metabolism; NAD; Research; Schizophyllum

1965
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:5

    Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen

2003
Altered glycosylated PrP proteins can have different neuronal trafficking in brain but do not acquire scrapie-like properties.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: Aging; Alleles; Animals; Antibodies, Monoclonal; Asparagine; Blotting, Northern; Blotting, Southern; Blotting, Western; Brain; Carbohydrates; Cell Membrane; Cells, Cultured; Detergents; Disease Models, Animal; DNA; Embryo, Mammalian; Endopeptidase K; Endoplasmic Reticulum; Female; Genetic Vectors; Genotype; Glycoproteins; Glycosylation; Golgi Apparatus; Homozygote; Immunohistochemistry; Male; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Mice, Transgenic; Microscopy, Confocal; Models, Genetic; Mutation; Neurons; Phenotype; Polymerase Chain Reaction; Polysaccharides; Prions; Recombination, Genetic; RNA; RNA, Messenger; Scrapie; Solubility; Stem Cells; Threonine; Time Factors; Type C Phospholipases

2005
Asparagine synthesis in Zea mays.
    Biochimica et biophysica acta, 1967, Jul-25, Volume: 141, Issue:2

    Topics: Acetates; Aging; Asparagine; Biological Transport; Carbon Isotopes; Glucose; Ligases; Salts; Zea mays

1967
Comparison of system N in fetal hepatocytes and in related cell lines.
    The Journal of biological chemistry, 1983, May-25, Volume: 258, Issue:10

    Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Line; Ethylmaleimide; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Lithium; Liver; Liver Neoplasms; Sodium

1983
Transcriptional activation of ornithine decarboxylase in adult and neonatal hippocampal slices.
    Brain research. Developmental brain research, 1993, Aug-20, Volume: 74, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Asparagine; Blotting, Northern; Dactinomycin; Enzyme Activation; Female; Hippocampus; In Vitro Techniques; Kainic Acid; Ornithine Decarboxylase; Polyamines; Pregnancy; Rats; Rats, Sprague-Dawley; Seizures; Transcription, Genetic

1993
Age-dependent deamidation of alpha B-crystallin.
    FEBS letters, 1993, May-03, Volume: 322, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Amides; Amino Acid Sequence; Animals; Asparagine; Cattle; Crystallins; Humans; Molecular Sequence Data; Peptide Mapping

1993
Quantitation of asparagine-101 deamidation from alpha-A crystallin during aging of the human lens.
    Current eye research, 1998, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Asparagine; Child; Child, Preschool; Crystallins; Deamination; Humans; Infant; Lens, Crystalline; Middle Aged

1998
Determination of the in vivo deamidation rate of asparagine-101 from alpha-A crystallin using microdissected sections of the aging human lens.
    Experimental eye research, 1998, Volume: 67, Issue:1

    Topics: Adolescent; Adult; Aging; Amides; Asparagine; Child; Child, Preschool; Crystallins; Dissection; Glutamine; Half-Life; Humans; Lens, Crystalline

1998
Deamidation of Asn-143 of gamma S crystallin from protein aggregates of the human lens.
    Current eye research, 2001, Volume: 22, Issue:2

    Topics: Aging; Asparagine; Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallins; Deamination; Glutamine; Humans; Lens, Crystalline; Middle Aged; Molecular Weight

2001
Maturation-dependent neointima formation in fowl aorta.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2001, Volume: 130, Issue:1

    Topics: Actins; Aging; Animals; Aorta, Abdominal; Arginine; Asparagine; Blood Pressure; Chickens; Cholesterol; Female; Hyperplasia; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nitric Oxide; Ornithine; Phenylalanine; Tunica Intima

2001
Transfer RNA in aging Drosophila: II. Isoacceptor patterns.
    Mechanisms of ageing and development, 1979, Volume: 10, Issue:1-2

    Topics: Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Asparagine; Drosophila melanogaster; Histidine; Leucine; Male; RNA, Transfer; Tyrosine

1979
Age-dependent deamidation of the major intrinsic polypeptide from lens membranes.
    Current eye research, 1991, Volume: 10, Issue:9

    Topics: Aging; Amino Acid Sequence; Animals; Aquaporins; Asparagine; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Deamination; Eye Proteins; Lens, Crystalline; Membrane Glycoproteins; Molecular Sequence Data; Protein Processing, Post-Translational; Radioimmunoassay

1991
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
    Journal of neurochemistry, 1973, Volume: 21, Issue:5

    Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine

1973
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1966, Dec-15, Volume: 171, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine

1966