asiatic acid has been researched along with Disease Models, Animal in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 16 (64.00) | 24.3611 |
| 2020's | 7 (28.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Pan, JC; Tu, LL; Yin, LN; Zhang, Y; Zhang, YW; Zheng, GL | 1 |
| Chen, X; Chen, Y; Wang, S; Yin, L; Zhang, Y; Zhao, P; Zhou, Y | 1 |
| Hu, Z; Liu, H; Shang, P; Tang, Q; Tang, S; Xu, J; Yu, X; Zheng, G | 1 |
| Chen, S; Feng, Z; Lao, L; Lin, X; Pang, L; Pang, X; Qiao, Q; Vonglorkham, S; Wang, D; Wei, J | 1 |
| Gold, D; Juszczak, K; Kluz, T; Misiek, M; Poleszak, E; Radziszewski, P; Rogowski, A; Sieńko, J; Stangel-Wójcikiewicz, K; Wróbel, A; Zapała, Ł | 1 |
| An, JH; Chung, KH; Kim, EK; Lee, KJ; Lee, Y; Moon, GH | 1 |
| Alfred, MG; Nkazimulo, MB; Tagumirwa, MC; Vuyisile, MM | 1 |
| Fan, Y; Guo, X; Han, L; Hou, Y; Liu, T; Luo, G; Ma, X; Matsabisa, M; Qin, L; Sun, W; Wu, L; Xu, G; Xu, T; Zhou, J | 1 |
| Kamble, SM; Patil, CR | 1 |
| Ayyanar, R; Mani, V; Nagappan, A; Namasivayam, N; Renganathan, S; Siddique, AI | 1 |
| Chaisawang, P; Pannangrong, W; Welbat, JU; Wigmore, P | 1 |
| Bai, F; Feng, Z; Lao, L; Lin, X; Pang, L; Pang, X; Qiao, Q; Sun, X; Wang, D; Wei, J | 1 |
| Dai, Y; Li, Y; Lv, Y; Qian, Y; Quan, M; Wang, Z; Xin, HB | 1 |
| Li, HY; Liu, YZ; Meng, Z; Si, CY; Teng, S | 1 |
| Bae, ON; Kassab, M; Lee, KY; Majid, A; Weinstock, S | 1 |
| Bailey, H; Ceremuga, TE; Criss, J; Fried, J; Johnson, AD; Kenner, C; Lathrop, K; Linton, J; Lucia, A; Padron, G; Stailey, O; Taylor, A; Valdivieso, D | 1 |
| Chen, YP; Liu, J; Lu, Q; Shang, J; Sun, HB; Wang, X; Yu, DS; Zhang, LY | 1 |
| Bunbupha, S; Kukongviriyapan, U; Kukongviriyapan, V; Pakdeechote, P; Prachaney, P; Welbat, JU | 1 |
| Mabandla, MV; Mavondo, GA; Mkhwananzi, BN | 1 |
| Bavbek, M; Bodur, E; Gurcan, O; Gurcay, AG; Karaca, EU; Kazanci, A; Senturk, S; Turkoglu, OF | 1 |
| Ahn, N; Frenkel, MB; Goudreau, J; Greenberg, EJ; Kassab, M; Krishnamurthy, RG; Majid, A; Min, J; Panickar, KS; Senut, MC; Yu, SW; Zemke, D | 1 |
| Gao, J; Liu, JK; Qian, JJ; Xiong, YY; Xu, MF; Zhu, L | 1 |
| Bae, ON; Baek, SH; Fitzgerald, SD; Goudreau, J; Hejabian, S; Kassab, M; Lee, KY; Majid, A; Moussa, A; Reeves, M; Rumbeiha, W; Serfozo, K; Stein, G | 1 |
| Bourdette, D; Gold, BG; Gold, SA; Koop, DR; Soumyanath, A; Yu, X; Zhong, YP | 1 |
1 trial(s) available for asiatic acid and Disease Models, Animal
| Article | Year |
|---|---|
Pre-infection administration of asiatic acid retards parasitaemia induction in Plasmodium berghei murine malaria infected Sprague-Dawley rats.
Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Malaria; Male; Mice; Parasitemia; Pentacyclic Triterpenes; Plasmodium berghei; Pre-Exposure Prophylaxis; Rats; Rats, Sprague-Dawley | 2016 |
24 other study(ies) available for asiatic acid and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Liver-targeted delivery of asiatic acid nanostructured lipid carrier for the treatment of liver fibrosis.
Topics: Animals; Carbon Tetrachloride; Cell Line; Cell Proliferation; Chemistry, Pharmaceutical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug Liberation; Lipids; Liver; Liver Cirrhosis; Liver Function Tests; Male; Mice; Mice, Inbred ICR; Nanostructures; Particle Size; Pentacyclic Triterpenes; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Surface Properties; Ursodeoxycholic Acid | 2021 |
Preparation and evaluation of PEGylated asiatic acid nanostructured lipid carriers on anti-fibrosis effects.
Topics: Administration, Oral; Animals; Biological Availability; Centella; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Intestinal Absorption; Lipids; Liver Cirrhosis; Male; Mice; Mice, Inbred ICR; Nanostructures; Particle Size; Pentacyclic Triterpenes; Polyethylene Glycols; Rats; Rats, Sprague-Dawley | 2020 |
Asiatic acid ameliorates obesity-related osteoarthritis by inhibiting myeloid differentiation protein-2.
Topics: Animals; Anti-Inflammatory Agents; Cartilage; Cell Survival; Chondrocytes; Cytokines; Diet, High-Fat; Disease Models, Animal; Extracellular Matrix; Humans; Inflammation; Lymphocyte Antigen 96; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; NF-kappa B; Obesity; Osteoarthritis; Palmitates; Pentacyclic Triterpenes | 2020 |
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Proteins; Cell Cycle Checkpoints; Cell Line; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Endoplasmic Reticulum Stress; Galactosamine; Hepatocytes; Humans; Lipopolysaccharides; Liver; Male; Mice, Inbred C57BL; Pentacyclic Triterpenes | 2020 |
The Potential of Asiatic Acid in the Reversion of Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Biomarkers; Cyclophosphamide; Cystitis; Disease Models, Animal; Hemorrhage; Pentacyclic Triterpenes; Rats; Urothelium | 2021 |
Immunomodulatory and Anti-inflammatory Effects of Asiatic Acid in a DNCB-Induced Atopic Dermatitis Animal Model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Collagen; Cytokines; Dermatitis, Atopic; Dermis; Dinitrochlorobenzene; Disease Models, Animal; Epidermis; Female; Gene Expression Regulation; Humans; Immunologic Factors; Immunomodulation; Lymphoid Tissue; MAP Kinase Signaling System; Mast Cells; Mice; Mice, Inbred BALB C; NF-kappa B; Organ Size; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
ASIATIC ACID INFLUENCES GLUCOSE HOMEOSTASIS IN
Topics: Animals; Disease Models, Animal; Glucose; Glucose Tolerance Test; Homeostasis; Insulin; Lactic Acid; Malaria; Male; Parasitemia; Pentacyclic Triterpenes; Plasmodium berghei; Rats; Rats, Sprague-Dawley | 2016 |
Protective effects of asiatic acid in a spontaneous type 2 diabetic mouse model.
Topics: Animals; Biomarkers; Diabetes Mellitus, Type 2; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Hypoglycemic Agents; Lipid Metabolism; Lipids; Mice; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Pioglitazone; Proto-Oncogene Proteins c-akt; Signal Transduction; Thiazolidinediones | 2017 |
Asiatic Acid Ameliorates Doxorubicin-Induced Cardiac and Hepato-Renal Toxicities with Nrf2 Transcriptional Factor Activation in Rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Doxorubicin; Female; Heart Diseases; Heart Rate; HeLa Cells; Humans; Kidney; Kidney Diseases; Liver; Male; MCF-7 Cells; Myocardium; NF-E2-Related Factor 2; Oxidative Stress; Pentacyclic Triterpenes; Rats, Wistar; Signal Transduction | 2018 |
Asiatic acid abridges pre-neoplastic lesions, inflammation, cell proliferation and induces apoptosis in a rat model of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Cytochrome P-450 Enzyme System; Disease Models, Animal; Down-Regulation; Liver; Male; Pentacyclic Triterpenes; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Up-Regulation | 2017 |
Neuroprotective Properties of Asiatic Acid against 5-Fluorouracil Chemotherapy in the Hippocampus in an Adult Rat Model.
Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Behavior, Animal; Cell Cycle Checkpoints; Disease Models, Animal; Doublecortin Protein; Fluorouracil; Hippocampus; Male; Memory; Memory Disorders; Nerve Tissue Proteins; Neurogenesis; Neuroprotective Agents; Oxidative Stress; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Topics: Animals; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Endoplasmic Reticulum Stress; Hepatocytes; Humans; Lipid Metabolism; Male; Non-alcoholic Fatty Liver Disease; Pentacyclic Triterpenes; Potentilla; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Asiatic acid protests against myocardial ischemia/reperfusion injury via modulation of glycometabolism in rat cardiomyocyte.
Topics: Animals; Centella; Disease Models, Animal; Glucose Transporter Type 4; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Pentacyclic Triterpenes; PPAR gamma; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley | 2018 |
Asiatic acid inhibits cardiac fibrosis throughNrf2/HO-1 and TGF-β1/Smads signaling pathways in spontaneous hypertension rats.
Topics: Animals; Cells, Cultured; Collagen; Disease Models, Animal; Endomyocardial Fibrosis; Fibroblasts; Heme Oxygenase-1; Humans; Male; Membrane Proteins; Myocardium; NF-E2-Related Factor 2; Pentacyclic Triterpenes; Rats; Rats, Inbred WKY; RNA, Small Interfering; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta1 | 2019 |
Neuroprotective effect of asiatic acid in rat model of focal embolic stroke.
Topics: Animals; Apoptosis Inducing Factor; Cytochromes c; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Mitochondria; Neurons; Neuroprotective Agents; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Rats, Wistar | 2014 |
Evaluation of the anxiolytic and antidepressant effects of asiatic acid, a compound from Gotu kola or Centella asiatica, in the male Sprague Dawley rat.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Centella; Depression; Disease Models, Animal; Flumazenil; Male; Midazolam; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Plant Preparations; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triterpenes | 2015 |
Asiatic acid mitigates hyperglycemia and reduces islet fibrosis in Goto-Kakizaki rat, a spontaneous type 2 diabetic animal model.
Topics: Animals; Blood Glucose; Centella; Diabetes Mellitus, Type 2; Disease Models, Animal; Fibronectins; Fibrosis; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Islets of Langerhans; Male; Pancreatic Diseases; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Rats, Inbred Strains | 2015 |
Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension.
Topics: Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Collagen; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha; Vascular Remodeling; Ventricular Remodeling | 2015 |
Effect of Asiatic Acid on the Treatment of Spinal Cord Injury: An Experimental Study in Rats.
Topics: Animals; Disease Models, Animal; Laminectomy; Male; Neuroprotective Agents; Pentacyclic Triterpenes; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recovery of Function; Spinal Cord Injuries | 2017 |
Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Cell Line; Cell Survival; Cytochromes c; Disease Models, Animal; Glucose; Immunoglobulin G; Infarction, Middle Cerebral Artery; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Pentacyclic Triterpenes; Severity of Illness Index; Time Factors; Treatment Outcome; Triterpenes | 2009 |
Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells.
Topics: Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Blotting, Western; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cell Line, Tumor; Cell Survival; Centella; Cognition; Dementia; Disease Models, Animal; Dose-Response Relationship, Drug; Flow Cytometry; Glutathione; Heat-Shock Proteins; Humans; Lipid Peroxidation; Membrane Potential, Mitochondrial; Memory; Mice; Neuroblastoma; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Pentacyclic Triterpenes; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sirtuin 1; Sodium Glutamate; Superoxide Dismutase; Time Factors; Transcription Factors | 2012 |
Asiatic acid attenuates infarct volume, mitochondrial dysfunction, and matrix metalloproteinase-9 induction after focal cerebral ischemia.
Topics: Animals; Brain Infarction; Disease Models, Animal; Enzyme Activation; Enzyme Induction; Female; Male; Matrix Metalloproteinase 9; Mice; Mitochondria; Neuroprotective Agents; Pentacyclic Triterpenes; Rats; Rats, Sprague-Dawley; Stroke | 2012 |
Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.
Topics: Administration, Oral; Animals; Cell Line, Tumor; Centella; Disease Models, Animal; Ethanol; Flavonoids; Humans; Male; Medicine, Ayurvedic; Nerve Crush; Nerve Regeneration; Neurites; Pentacyclic Triterpenes; Plant Extracts; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Triterpenes | 2005 |