asialo-gm1-ganglioside and Graves-Disease

asialo-gm1-ganglioside has been researched along with Graves-Disease* in 2 studies

Other Studies

2 other study(ies) available for asialo-gm1-ganglioside and Graves-Disease

ArticleYear
Anti-fucosyl-GM1 ganglioside IgG and IgM autoantibodies in human serum: no link to pathology.
    Immunology letters, 1996, Volume: 52, Issue:2-3

    Anti-fucosyl-GM1 ganglioside antibodies were detected in sera of five persons: four patients with autoimmune neuropathies and more recently, IgG antibodies in one with Graves' disease (Adler et al., Autoimmunity 18, 149-152, 1994) [1]. In the latter case, we were unable to find any relation between the occurrence of antibodies and thyroid disease. Now we report a detailed study on the anti-glycolipid antibodies in this patient. We found that her serum contained not only IgG but also a high level of anti-FucGM1 IgM antibodies, with a titer stable over a period of 5 years of treatment and follow-up. The carbohydrate structure of the epitope recognized by IgG and some of IgM antibodies seems to consist of Fuc-Gal-GalNAc-Gal- or a part of this sequence. Moreover, this patient's serum contained other IgM antibodies active against FucGM1 and also asialo GM1 glycolipids. Our results indicate that anti-FucGM1 ganglioside antibodies of G and M classes occur in serum of this patient with no apparent adverse health effects.

    Topics: Antibody Specificity; Autoantibodies; Carbohydrate Sequence; Cross Reactions; Female; G(M1) Ganglioside; Graves Disease; Humans; Immunoglobulin G; Immunoglobulin M; Middle Aged; Molecular Sequence Data; Nervous System Diseases; Neutralization Tests

1996
Anti-asialo-GM1 antibody in sera from patients with Graves' disease and Hashimoto's thyroiditis.
    Lancet (London, England), 1980, Jul-26, Volume: 2, Issue:8187

    Topics: Autoantibodies; Complement Fixation Tests; G(M1) Ganglioside; Glycosphingolipids; Graves Disease; Humans; Thyroiditis, Autoimmune

1980