ascorbic-acid and Peripheral-Nervous-System-Neoplasms

ascorbic-acid has been researched along with Peripheral-Nervous-System-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for ascorbic-acid and Peripheral-Nervous-System-Neoplasms

Article	Year
Inhibitory effect of sodium ascorbate on ethylurea and sodium nitrite carcinogensis and negative findings in progeny after intestinal inoculation of precursors into pregnant hamsters. Journal of the National Cancer Institute, 1975, Volume: 55, Issue:6 To assess their carcinogenic effects, the ethylnitrosourea (ENU) precursors, ethylurea and sodium nitrite, [were administered to pregnant hamsters as a single intragastic] dose on day 15 of gestation, or introduced into the cecum on day 14. Since sodium ascorbate (NaASC) inhibits the biosynthesis of nitrosamides, identical doses of the precursors were given concomitantly with NaASC. Progeny of mothers treater intragastrically developed significant incidences of neurogenic tumors of the peripheral nervous system, with a predominance in females. The concurrent administration of NaASC with ENU precursors prevented carcinogenic effects in the progency, whereas the simultaneous inoculation of the precursors into the cecum produced no carcinogenic effects in the offspring. Topics: Animals; Ascorbic Acid; Astrocytoma; Brain Neoplasms; Cecum; Cricetinae; Ethylnitrosourea; Female; Intubation, Gastrointestinal; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrites; Nitroso Compounds; Peripheral Nervous System Neoplasms; Pons; Pregnancy; Sex Factors; Urea	1975
[Ascorbic acid hinderance of the prenatal carcinogenic effect of ethylurea and nitrite]. Die Naturwissenschaften, 1973, Volume: 60, Issue:11 Topics: Animals; Ascorbic Acid; Brain Neoplasms; Carcinogens; Cranial Nerves; Drug Interactions; Female; Gestational Age; Nitrites; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms; Urea	1973

Article

Year

Inhibitory effect of sodium ascorbate on ethylurea and sodium nitrite carcinogensis and negative findings in progeny after intestinal inoculation of precursors into pregnant hamsters.

Journal of the National Cancer Institute, 1975, Volume: 55, Issue:6

To assess their carcinogenic effects, the ethylnitrosourea (ENU) precursors, ethylurea and sodium nitrite, [were administered to pregnant hamsters as a single intragastic] dose on day 15 of gestation, or introduced into the cecum on day 14. Since sodium ascorbate (NaASC) inhibits the biosynthesis of nitrosamides, identical doses of the precursors were given concomitantly with NaASC. Progeny of mothers treater intragastrically developed significant incidences of neurogenic tumors of the peripheral nervous system, with a predominance in females. The concurrent administration of NaASC with ENU precursors prevented carcinogenic effects in the progency, whereas the simultaneous inoculation of the precursors into the cecum produced no carcinogenic effects in the offspring.

Topics: Animals; Ascorbic Acid; Astrocytoma; Brain Neoplasms; Cecum; Cricetinae; Ethylnitrosourea; Female; Intubation, Gastrointestinal; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrites; Nitroso Compounds; Peripheral Nervous System Neoplasms; Pons; Pregnancy; Sex Factors; Urea

1975

[Ascorbic acid hinderance of the prenatal carcinogenic effect of ethylurea and nitrite].

Die Naturwissenschaften, 1973, Volume: 60, Issue:11

Topics: Animals; Ascorbic Acid; Brain Neoplasms; Carcinogens; Cranial Nerves; Drug Interactions; Female; Gestational Age; Nitrites; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms; Urea

1973