ascorbic-acid and Meniere-Disease

To perform a trial to assess the efficacy of radical scavengers, i.e. rebamipide, vitamin C and glutathione, for the treatment of Ménière's disease (MD).. Rebamipide (300 mg/day), vitamin C (600 mg/day) and/or glutathione (300 mg/day) were given orally for at least 8 weeks to 25 patients with poorly controlled MD.. Of 22 patients, 21 showed marked improvement of vertigo; 12/27 ears showed improvement of hearing disorders; 17/27 ears showed improvement of tinnitus; and 18/25 patients showed improvement of disability.. This study suggests that treatment using radical scavengers has the potential to become an effective new therapy for MD.

Topics: Adult; Aged; Alanine; Antioxidants; Ascorbic Acid; Female; Free Radical Scavengers; Glutathione; Hearing Loss; Humans; Male; Meniere Disease; Middle Aged; Pilot Projects; Quinolones; Tinnitus; Treatment Failure; Vertigo

Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Ascorbic Acid; Ear, Inner; Glycosaminoglycans; Hormones; Humans; Hyaluronoglucosaminidase; Labyrinthine Fluids; Meniere Disease; Prednisolone; Proteins; Vitamin B Complex

Topics: Adrenal Cortex Hormones; Adult; Ascorbic Acid; Carbohydrate Metabolism; Diet Therapy; Estrogens; Female; Glucose; Glucose Tolerance Test; Gonadal Steroid Hormones; Humans; Male; Meniere Disease; Middle Aged; Progesterone; Pyridoxine; Testosterone; Vitamin B 12

Topics: Ascorbic Acid; Choline; Deafness; Flavanones; Flavonoids; Glycosides; Inositol; Meniere Disease; Methionine; Niacin; Nicotinic Acids; Pantothenic Acid; Pyridoxine; Riboflavin; Thiamine; Vitamin B 12

Topics: Ascorbic Acid; Citrus; Deafness; Flavonoids; Folic Acid; Hearing Loss, Sensorineural; Meniere Disease; Vitamin B Complex; Vitamins

Topics: Ascorbic Acid; Diet; Flavonoids; Humans; Labyrinth Diseases; Labyrinthitis; Meniere Disease; Vitamins