ascorbic-acid and Hypoproteinemia

Topics: Amyloidosis; Ascorbic Acid; Biopsy; Humans; Hypoproteinemia; Kidney; Kidney Diseases; Liver Extracts; Microscopy, Electron; Polyuria; Proteinuria

In chronic pancreatitis patients was found persistent state of oxidative stress on the level of malonic aldehyde, which ran against the lowered levels of antioxidant enzymatic and non-enzymatic composition, and it has been found in the state of hypoproteinemia proteinogram indices (P < 0.05). The use of complex treatment of patients with chronic pancreatitis multivitamin-aminoacid drug Moriamin forte contributes to a significant regression effects oxidative stress and reduces the effects of hypoproteinemia (P < 0.05).

Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amino Acids; Antioxidants; Ascorbic Acid; Catalase; Domperidone; Female; Gastrointestinal Agents; Humans; Hypoproteinemia; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Pancreatin; Pancreatitis, Chronic; Pantoprazole; Proton Pump Inhibitors; Superoxide Dismutase; Vitamin A; Vitamins

Oral administration of sodium fluoride (NaF; 40 mg/kg body weight) daily from day 6 of gestation to day 21 of lactation caused, compared with the distilled water control (group 2), significant reductions in body weight and feed consumption as well as concentration of glucose and protein in the serum of P- and F(1)-generation rats; however, sodium and potassium concentrations in the serum were significantly higher than those of the vehicle control (group 2). Administration of either vitamins C (50 mg/kg body weight/day), D (2 ng/0.2 ml olive oil/animal/day) or a combination of vitamins C+D+E along with NaF caused significant amelioration in body weight and feed consumption, as well as glucose, protein, sodium and potassium concentrations in the serum of P- and F(1)-generation rats compared with the NaF-only treated group. Withdrawal of NaF treatment during lactation caused significant amelioration in feed consumption (days 15-21 only), sodium, potassium, glucose and protein concentrations in the serum of both P- and F(1)-generation rats. Co- treatment with vitamin E (2 mg/0.2 ml olive oil/animal/day) caused significant amelioration in body weight (days 15 and 20 of gestation only), sodium, potassium, glucose (only in P-generation females) and protein (only in P-generation female) concentrations in the serum of rats than in NaF-treated rats alone. It is concluded that co-treatment with vitamins C, D and C+D+E were found more effective in ameliorating NaF-induced effects than vitamin E and withdrawal of NaF treatment during lactation.

Topics: Administration, Oral; Animals; Animals, Newborn; Animals, Suckling; Antioxidants; Ascorbic Acid; Blood Glucose; Blood Proteins; Body Weight; Drug Therapy, Combination; Eating; Female; Hypoglycemia; Hypoproteinemia; Lactation; Male; Potassium; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sodium; Sodium Fluoride; Vitamin D; Vitamin E; Vitamins

Nephrotoxicity of daunorubicin in rats and effect of tocopherol and ascorbic acid on lesions induced in kidneys by daunorubicin were examined. Daunorubicin induced nephrotic syndrome with proteinuria and hypoproteinemia. Histological changes in the glomeruli appeared as a dilatation of capillary loops and enlargement of the urinary space. The glomerular basement membrane showed minimal thickening. In tubuli protein casts were noticed. No beneficial influence of tocopherol and ascorbic acid on daunorubicin related nephrotoxicity was observed.

Topics: Animals; Ascorbic Acid; Daunorubicin; Hypoproteinemia; Kidney; Kidney Glomerulus; Male; Nephrotic Syndrome; Proteinuria; Rats; Rats, Wistar; Vitamin E

Topics: Abdomen; Adrenal Cortex Hormones; Ascorbic Acid; Humans; Hypoproteinemia; Postoperative Care; Statistics as Topic; Surgical Procedures, Operative; Surgical Wound Dehiscence; Wound Healing