ascorbic-acid and HIV-Associated-Lipodystrophy-Syndrome

ascorbic-acid has been researched along with HIV-Associated-Lipodystrophy-Syndrome* in 1 studies

Trials

1 trial(s) available for ascorbic-acid and HIV-Associated-Lipodystrophy-Syndrome

Article	Year
Effect of antioxidants on glucose metabolism and plasma lipids in HIV-infected subjects with lipoatrophy. Journal of acquired immune deficiency syndromes (1999), 2003, Aug-15, Volume: 33, Issue:5 Ten HIV-infected nucleoside reverse transcriptase inhibitor-treated subjects with lipoatrophy or sustained hyperlactatemia were given antioxidants: vitamins C, E, and N-acetyl cysteine. After 24 weeks, anthropometrics did not change significantly, except for a modest decrease in the waist-to-hip ratio. Fasting low-density lipoprotein cholesterol trended toward lower values. Fasting glucose significantly increased along with a significant increase in homeostatic model assessment values, reflecting an increase in insulin resistance. Controlled trials are required to evaluate directly the effects of these agents on lipid and glucose metabolism. Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Body Composition; Cholesterol; Female; Glucose; HIV-Associated Lipodystrophy Syndrome; Hospitals, University; Humans; Lipids; Male; Middle Aged; Ohio; Pilot Projects; Reverse Transcriptase Inhibitors; Vitamin E	2003

Article

Year

Effect of antioxidants on glucose metabolism and plasma lipids in HIV-infected subjects with lipoatrophy.

Journal of acquired immune deficiency syndromes (1999), 2003, Aug-15, Volume: 33, Issue:5

Ten HIV-infected nucleoside reverse transcriptase inhibitor-treated subjects with lipoatrophy or sustained hyperlactatemia were given antioxidants: vitamins C, E, and N-acetyl cysteine. After 24 weeks, anthropometrics did not change significantly, except for a modest decrease in the waist-to-hip ratio. Fasting low-density lipoprotein cholesterol trended toward lower values. Fasting glucose significantly increased along with a significant increase in homeostatic model assessment values, reflecting an increase in insulin resistance. Controlled trials are required to evaluate directly the effects of these agents on lipid and glucose metabolism.

Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; Body Composition; Cholesterol; Female; Glucose; HIV-Associated Lipodystrophy Syndrome; Hospitals, University; Humans; Lipids; Male; Middle Aged; Ohio; Pilot Projects; Reverse Transcriptase Inhibitors; Vitamin E

2003