ascorbic-acid and Growth-Disorders

Topics: Adolescent; Arrhythmias, Cardiac; Ascorbic Acid; Blood Transfusion; Child; Cholelithiasis; Deferoxamine; Endocrine System Diseases; Female; Folic Acid; Growth Disorders; Heart Failure; Hematopoiesis; Humans; Iron; Leg Ulcer; Liver Diseases; Male; Pericarditis; Splenectomy; Thalassemia; Vitamin E

Topics: Adolescent; Adult; Ascorbic Acid; Blood Transfusion; Cardiomyopathies; Deferoxamine; Dose-Response Relationship, Drug; Ferritins; Growth Disorders; Heart Diseases; Hemosiderosis; Humans; Iron; Iron Chelating Agents; Liver; Liver Diseases; Pancreatic Diseases; Parathyroid Diseases; Pituitary Diseases; Thyroid Function Tests

Topics: Animal Feed; Animal Husbandry; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Chiroptera; Growth Disorders; Male; Nutritional Requirements; Weight Gain

Because of the high prevalence of iron-deficiency anemia in Brazil, individual control measures tend to be ineffective, and fortification of foods with iron is considered the most effective method to fight anemia.. To evaluate the effectiveness of fortification of drinking water with iron and vitamin C in the reduction of anemia in children in day-care centers in Belo Horizonte, Brazil.. This before-and-after study evaluated 318 children aged 6 to 74 months. Identification data and data on socioeconomic variables were collected; anthropometric and biochemical measurements were performed before and after 5 months of fortification of water with 5 mg of elemental iron and 50 mg of ascorbic acid per liter. The fortified water was used for drinking and cooking at the day-care center. Wilcoxon's nonparametric test was used to evaluate the differences in continuous variables, and McNemar's test was used to compare the prevalence rates of anemia.. The prevalence of anemia decreased significantly from 29.3% before fortification to 7.9% at the end of the study, with a significant increase in hemoglobin levels. Reductions in the prevalence rates of stunting and underweight were observed.. Fortification of water with iron and vitamin C significantly reduced the prevalence of anemia and improved nutritional status among children attending day-care centers.

Topics: Anemia, Iron-Deficiency; Ascorbic Acid; Brazil; Child; Child Day Care Centers; Child, Preschool; Drinking Water; Female; Growth Disorders; Hemoglobins; Humans; Infant; Iron, Dietary; Longitudinal Studies; Male; Nutritional Status; Prevalence; Thinness; Urban Health; Water Supply

The influence of extraneous supplementation of L-ascorbic acid in chronic chlordane toxicity has been studied in rats. Oral administration of chlordane brings about a marked growth retardative effect, stimulates vitamin C synthesis in the system, elevates the vitamin C status of the liver and kidney tissues and also the urinary excretion. It inhibits the activities of acid and alkaline phosphatases, SDH and Mg2+-ATPase of both hepatic and renal tissues. The activities of serum and mitochondrial GOT, serum alkaline phosphatase, and glucose-6-phosphatase of both hepatic and renal tissues are markedly stimulated. The normal histological patterns of both liver and kidney tissues are grossly altered under chlordane toxicity condition. There occurs marked increase in the hepatic lipid composition. Supplementation of L-ascorbic acid in high doses to the chlordane treated rats can effectively counteract some of these alterations in respect of enzyme activities, morphological characteristics and of hepatic lipid composition.

Topics: Animals; Ascorbic Acid; Chlordan; Diet; Growth Disorders; Hypertrophy; Kidney; Liver; Male; Rats; Stereoisomerism

1. Rats toxicated with vanadium pentoxide showed drastic retardation in growth rate and supplementation of L-ascorbic acid to these rats could not reverse this effect. The urinary excretion of L-ascorbic acid and D-glucuronic acid was decreased in the toxicated group of rats. 2. Considerable lowering of L-ascorbic acid content of the liver tissues of rats was observed under vanadium toxicated conditions. Supplementation of L-ascorbic acid to this group raised the tissue Vitamin C reserve considerably. 3. The normal histological patterns of the liver and kidney tissues of rats were severely disturbed under vanadium toxicated conditions. L-ascorbic acid supplementation to this group of rats showed marked signs of restoration in this respect. 4. Vanadium pentoxide treatment brought about a significant reduction in the biosynthetic capacity of L-ascorbic acid, along with an enhanced utilization of this vitamin. Subsequent supplementation of L-ascorbic acid to the toxicated group of rats was found to be effective in reversing these effects almost to the basal level.

Topics: Animals; Ascorbic Acid; Body Weight; Glucuronates; Growth Disorders; Hemoglobins; Kidney; Liver; Male; Organ Size; Rats; Time Factors; Vanadium

Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Chronic Disease; Female; Growth Disorders; Hematuria; Humans; Infant, Newborn; Liver; Liver Diseases; Male; Methionine; Pregnancy; Tyrosine

Topics: Animals; Ascorbic Acid; Collagen; Colorimetry; Diet; Elastin; Erythrocyte Count; FIGLU Test; Folic Acid Deficiency; Growth Disorders; Hematocrit; Hemoglobins; Hydroxylation; Hydroxyproline; Leukocyte Count; Male; Proline; Protein Biosynthesis; Rats; Skin; Trichloroacetic Acid; Tritium

Topics: Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Child Development; Chromatography, Paper; Diet Therapy; Fatigue; Feeding Behavior; Female; Growth Disorders; Humans; Infant, Newborn; Infant, Premature, Diseases; Intelligence; Intelligence Tests; Phenylalanine; Pregnancy; Pregnancy Complications; Tyrosine

Topics: Acoustic Stimulation; Adrenal Glands; Alcoholic Intoxication; Animals; Ascorbic Acid; Body Temperature; Chlorpromazine; Corticosterone; Depression, Chemical; Ethanol; Female; Growth Disorders; Humans; Hypothalamus; Hypothermia; Rats

Topics: Anemia; Ascorbic Acid; Deficiency Diseases; Growth Disorders; Hepatomegaly; Humans; Infant; Male; Rickets; Scurvy; Splenomegaly; Thrombocytopenia; Vitamin D

Feeding the environmental toxicant cadmium to young Japanese quail for 4 weeks produced growth retardation, severe anemia, low concentrations of iron in the liver, and high concentrations of cadmium in the liver. Dietary ascorbic acid supplements almost completely prevented the anemia and improved the growth rate but did not markedly alter concentrations of iron or cadmium in the liver.

Topics: Anemia; Animals; Ascorbic Acid; Birds; Cadmium; Copper; Drug Antagonism; Environmental Exposure; Female; Growth Disorders; Hematocrit; Iron; Liver; Male; Trace Elements; Zinc

Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Female; Growth Disorders; Humans; Pregnancy; Scurvy; Vitamins