ascorbic-acid and Foot-Diseases

Consumer concern on the quality of products and animal welfare has greatly increased during the past decades. Dietary synthetic antibiotic products used as growth promoters have been restricted or banned in many countries. Edible plants, essential oils, or their main components were suggested as natural feed supplements to improve growth, products' quality, and welfare-related parameters. Thymol (THY), a main component of oregano essential oil, has been proved as an effective antimicrobial and antioxidant compound. Tocopherol (TOC) evidenced antioxidant activity with potential as a growth promoter and a synergic antioxidant activity between TOC and ascorbyl palmitate (AP) has also been reported. Herein, we evaluated whether broiler diet supplementation with THY, and THY with a formulation mix containing TOC and AP (1:0.5:0.5, respectively) have potential as growth enhancers under commercial conditions. Potential protective effects against foot pad dermatitis and hock burns were also evaluated. Newly hatched male broiler chicks with similar body weight (BW) were randomly assigned to 1 of 7 groups (4 replicates each) as follows: Basal (no feed supplements added), Promotor (Basal + 6.26 μmol flavomycin/kg feed), BHT (Basal + 1.33 mmol of buthylated hidroxytoluene (BHT)/kg feed), Prom-BHT (Basal + 6.26 μmol flavomycin/kg feed + 1.33 mmol of BHT/kg feed), TOC-AP (Basal + 0.67 mmoles of TOC + 0.67 mmoles of AP/kg feed), THY (Basal + 1.33 mmoles of THY/kg feed), and THY-TOC-AP (Basal + 0.67 mmoles of THY + 0.67 mmoles of a mix 1:1 of TOC-AP). Along 7 wk, BW, feed intake, and feed conversion ratio were evaluated. Skin injuries were assessed at 35 d of age. At the end of the study (42 d), compared to Basal group, similarly enhanced final BW were observed in all groups but TOC-AP. No main differences between groups were detected in feed intake, feed conversion ratio, or skin injuries. Findings suggest that THY itself or in combination with TOC-AP may have value as a natural growth enhancer alternative for broilers.

Topics: alpha-Tocopherol; Animal Feed; Animals; Ascorbic Acid; Chickens; Diet; Dietary Supplements; Foot Diseases; Growth Substances; Male; Poultry Diseases; Random Allocation; Thymol

We report a case of scurvy, which is rarely encountered in Japan. A 75-year-old male was hospitalized with diffuse subcutaneous hemorrhaging of both feet, pain on walking, and shortness of breath. A remarkably low serum level of vitamin C was confirmed. Administration of ascorbic acid dramatically improved his clinical symptoms. Improvement paralleled the increase of serum vitamin C level. This case underscores the important role of vitamin C on the integrity function of the vessel wall.

Topics: Aged; Ascorbic Acid; Foot Diseases; Hemorrhage; Humans; Japan; Male; Pain; Scurvy; Skin

Topics: Ascorbic Acid; Drug Therapy; Foot; Foot Diseases; Hand Dermatoses; Humans; Nails; Niacin; Ointments; Psoriasis; Vitamin A

Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Flavonoids; Foot Diseases; Hesperidin; Nutrition Therapy; Vitamins

Topics: Antifibrinolytic Agents; Ascorbic Acid; Aspirin; Collagen; Collagen Diseases; Foot Diseases; Hemostatics; Humans; Vitamin K; Vitamins

Topics: Ascorbic Acid; Foot; Foot Diseases; Humans; Pantothenic Acid; Vitamins; Warts